Gene: ERBB2
Ensembl ID : ENSG00000141736
Description: erb-b2 receptor tyrosine kinase 2
Gene Synonyms: C-ERB-2,C-ERB2,CD340,HER-2,HER2,MLN-19,NEU,NGL,P185(ERBB2)
39 APIs:
200 Possible Orthologues:

Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Drug resistance in ERBB2 KD mutants R-HSA-9665230
ERBB2 Regulates Cell Motility R-HSA-6785631
PI3K events in ERBB2 signaling R-HSA-1963642
Disease R-HSA-1643685
Signaling by ERBB2 KD Mutants R-HSA-9664565
Intracellular signaling by second messengers R-HSA-9006925
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Sema4D in semaphorin signaling R-HSA-400685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by ERBB2 ECD mutants R-HSA-9665348
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
SHC1 events in ERBB2 signaling R-HSA-1250196
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signaling by ERBB2 in Cancer R-HSA-1227990
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 R-HSA-1227986
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK1/MAPK3 signaling R-HSA-5684996
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Generic Transcription Pathway R-HSA-212436
GRB7 events in ERBB2 signaling R-HSA-1306955
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
MAPK family signaling cascades R-HSA-5683057
Signaling by PTK6 R-HSA-8848021
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Semaphorin interactions R-HSA-373755
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
PI3K/AKT Signaling in Cancer R-HSA-2219528
Negative regulation of the PI3K/AKT network R-HSA-199418
Developmental Biology R-HSA-1266738
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
MAPK family signaling cascades R-HSA-5683057
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
RNA Polymerase II Transcription R-HSA-73857
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by ERBB2 KD Mutants R-HSA-9664565
PI3K events in ERBB2 signaling R-HSA-1963642
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
GRB7 events in ERBB2 signaling R-HSA-1306955
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by ERBB2 in Cancer R-HSA-1227990
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Nervous system development R-HSA-9675108
PI3K/AKT Signaling in Cancer R-HSA-2219528
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Semaphorin interactions R-HSA-373755
Intracellular signaling by second messengers R-HSA-9006925
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
RAF/MAP kinase cascade R-HSA-5673001
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Sema4D in semaphorin signaling R-HSA-400685
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Downregulation of ERBB2 signaling R-HSA-8863795
Disease R-HSA-1643685
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK1/MAPK3 signaling R-HSA-5684996
PLCG1 events in ERBB2 signaling R-HSA-1251932
Axon guidance R-HSA-422475
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Signaling by ERBB2 R-HSA-1227986
RAF/MAP kinase cascade R-HSA-5673001
Downregulation of ERBB2 signaling R-HSA-8863795
Signal Transduction R-HSA-162582
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by PTK6 R-HSA-8848021
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 KD Mutants R-HSA-9664565
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Sema4D in semaphorin signaling R-HSA-400685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 in Cancer R-HSA-1227990
PI3K events in ERBB2 signaling R-HSA-1963642
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Nervous system development R-HSA-9675108
PLCG1 events in ERBB2 signaling R-HSA-1251932
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Signaling by ERBB2 R-HSA-1227986
Generic Transcription Pathway R-HSA-212436
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Signaling by ERBB2 ECD mutants R-HSA-9665348
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Drug resistance in ERBB2 KD mutants R-HSA-9665230
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
Gene expression (Transcription) R-HSA-74160
GRB7 events in ERBB2 signaling R-HSA-1306955
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
PI3K/AKT Signaling in Cancer R-HSA-2219528
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
GRB2 events in ERBB2 signaling R-HSA-1963640
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Semaphorin interactions R-HSA-373755
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
ERBB2 Regulates Cell Motility R-HSA-6785631
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Signal Transduction R-HSA-162582
Downregulation of ERBB2 signaling R-HSA-8863795
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Sema4D in semaphorin signaling R-HSA-400685
Drug resistance in ERBB2 KD mutants R-HSA-9665230
GRB2 events in ERBB2 signaling R-HSA-1963640
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Semaphorin interactions R-HSA-373755
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ERBB2 in Cancer R-HSA-1227990
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Developmental Biology R-HSA-1266738
PLCG1 events in ERBB2 signaling R-HSA-1251932
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Gene expression (Transcription) R-HSA-74160
Signaling by ERBB2 ECD mutants R-HSA-9665348
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by ERBB2 R-HSA-1227986
Intracellular signaling by second messengers R-HSA-9006925
Axon guidance R-HSA-422475
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
GRB7 events in ERBB2 signaling R-HSA-1306955
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC1 events in ERBB2 signaling R-HSA-1250196
Disease R-HSA-1643685
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by PTK6 R-HSA-8848021
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
MAPK family signaling cascades R-HSA-5683057
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signaling by PTK6 R-HSA-8848021
ERBB2 Regulates Cell Motility R-HSA-6785631
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of the PI3K/AKT network R-HSA-199418
Disease R-HSA-1643685
Signaling by ERBB2 KD Mutants R-HSA-9664565
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Semaphorin interactions R-HSA-373755
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
Sema4D in semaphorin signaling R-HSA-400685
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
GRB7 events in ERBB2 signaling R-HSA-1306955
PI3K events in ERBB2 signaling R-HSA-1963642
PLCG1 events in ERBB2 signaling R-HSA-1251932
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by ERBB2 ECD mutants R-HSA-9665348
Downregulation of ERBB2 signaling R-HSA-8863795
Gene expression (Transcription) R-HSA-74160
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Generic Transcription Pathway R-HSA-212436
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Nervous system development R-HSA-9675108
Signaling by ERBB2 in Cancer R-HSA-1227990
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by ERBB2 R-HSA-1227986
SHC1 events in ERBB2 signaling R-HSA-1250196
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
ERBB2 Activates PTK6 Signaling R-HSA-8847993
GRB2 events in ERBB2 signaling R-HSA-1963640
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 KD Mutants R-HSA-9664565
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
Sema4D in semaphorin signaling R-HSA-400685
Axon guidance R-HSA-422475
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
SHC1 events in ERBB2 signaling R-HSA-1250196
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
GRB7 events in ERBB2 signaling R-HSA-1306955
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PLCG1 events in ERBB2 signaling R-HSA-1251932
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by ERBB2 ECD mutants R-HSA-9665348
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by PTK6 R-HSA-8848021
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Developmental Biology R-HSA-1266738
Semaphorin interactions R-HSA-373755
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
MAPK1/MAPK3 signaling R-HSA-5684996
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB2 in Cancer R-HSA-1227990
PI3K events in ERBB2 signaling R-HSA-1963642
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Axon guidance R-HSA-422475
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB2 R-HSA-1227986
Sema4D in semaphorin signaling R-HSA-400685
Signaling by ERBB2 in Cancer R-HSA-1227990
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Semaphorin interactions R-HSA-373755
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Signaling by PTK6 R-HSA-8848021
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Signaling by ERBB2 KD Mutants R-HSA-9664565
GRB2 events in ERBB2 signaling R-HSA-1963640
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Generic Transcription Pathway R-HSA-212436
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
SHC1 events in ERBB2 signaling R-HSA-1250196
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by ERBB2 ECD mutants R-HSA-9665348
Disease R-HSA-1643685
Downregulation of ERBB2 signaling R-HSA-8863795
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K events in ERBB2 signaling R-HSA-1963642
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
MAPK family signaling cascades R-HSA-5683057
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
ERBB2 Regulates Cell Motility R-HSA-6785631
GRB7 events in ERBB2 signaling R-HSA-1306955
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
PLCG1 events in ERBB2 signaling R-HSA-1251932
RNA Polymerase II Transcription R-HSA-73857
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
PI3K/AKT Signaling in Cancer R-HSA-2219528
RAF/MAP kinase cascade R-HSA-5673001
Semaphorin interactions R-HSA-373755
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
MAPK family signaling cascades R-HSA-5683057
PLCG1 events in ERBB2 signaling R-HSA-1251932
Axon guidance R-HSA-422475
GRB7 events in ERBB2 signaling R-HSA-1306955
RNA Polymerase II Transcription R-HSA-73857
GRB2 events in ERBB2 signaling R-HSA-1963640
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by ERBB2 in Cancer R-HSA-1227990
Generic Transcription Pathway R-HSA-212436
Signaling by ERBB2 R-HSA-1227986
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Disease R-HSA-1643685
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
ERBB2 Regulates Cell Motility R-HSA-6785631
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ERBB2 ECD mutants R-HSA-9665348
Downregulation of ERBB2 signaling R-HSA-8863795
SHC1 events in ERBB2 signaling R-HSA-1250196
PIP3 activates AKT signaling R-HSA-1257604
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Negative regulation of the PI3K/AKT network R-HSA-199418
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Sema4D in semaphorin signaling R-HSA-400685
Gene expression (Transcription) R-HSA-74160
Signaling by PTK6 R-HSA-8848021
Drug resistance in ERBB2 KD mutants R-HSA-9665230
PI3K events in ERBB2 signaling R-HSA-1963642
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Developmental Biology R-HSA-1266738
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Signal Transduction R-HSA-162582
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
SHC1 events in ERBB2 signaling R-HSA-1250196
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
GRB7 events in ERBB2 signaling R-HSA-1306955
Intracellular signaling by second messengers R-HSA-9006925
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Drug resistance in ERBB2 KD mutants R-HSA-9665230
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Developmental Biology R-HSA-1266738
Signaling by ERBB2 ECD mutants R-HSA-9665348
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
Signaling by ERBB2 R-HSA-1227986
Sema4D in semaphorin signaling R-HSA-400685
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 KD Mutants R-HSA-9664565
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
ERBB2 Regulates Cell Motility R-HSA-6785631
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K events in ERBB2 signaling R-HSA-1963642
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Disease R-HSA-1643685
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
PLCG1 events in ERBB2 signaling R-HSA-1251932
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downregulation of ERBB2 signaling R-HSA-8863795
Semaphorin interactions R-HSA-373755
Signaling by PTK6 R-HSA-8848021
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
Drug resistance in ERBB2 KD mutants R-HSA-9665230
GRB7 events in ERBB2 signaling R-HSA-1306955
Downregulation of ERBB2 signaling R-HSA-8863795
PIP3 activates AKT signaling R-HSA-1257604
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247
MAPK1/MAPK3 signaling R-HSA-5684996
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233
RNA Polymerase II Transcription R-HSA-73857
Signaling by ERBB2 KD Mutants R-HSA-9664565
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282
Negative regulation of the PI3K/AKT network R-HSA-199418
Developmental Biology R-HSA-1266738
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Semaphorin interactions R-HSA-373755
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244
MAPK family signaling cascades R-HSA-5683057
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Intracellular signaling by second messengers R-HSA-9006925
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by ERBB2 in Cancer R-HSA-1227990
Sema4D in semaphorin signaling R-HSA-400685
Axon guidance R-HSA-422475
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251
Nervous system development R-HSA-9675108
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
SHC1 events in ERBB2 signaling R-HSA-1250196
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910
PLCG1 events in ERBB2 signaling R-HSA-1251932
Signaling by ERBB2 R-HSA-1227986
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245
Gene expression (Transcription) R-HSA-74160
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000141736
LRG display in Ensembl gene LRG_724
NCBI gene (formerly Entrezgene) 2064
GeneCards 3430
HGNC Symbol HGNC:3430
MIM gene 164870
MIM morbid 619465
UniProtKB Gene Name X5DNK3
WikiGene 2064
Gene: LCK
Ensembl ID : ENSG00000182866
Description: LCK proto-oncogene, Src family tyrosine kinase
Gene Synonyms:
2 APIs:
120 Possible Orthologues:

Generation of second messenger molecules R-HSA-202433
Negative regulation of the PI3K/AKT network R-HSA-199418
Cell surface interactions at the vascular wall R-HSA-202733
Infectious disease R-HSA-5663205
Adaptive Immune System R-HSA-1280218
GPVI-mediated activation cascade R-HSA-114604
CD28 co-stimulation R-HSA-389356
Intracellular signaling by second messengers R-HSA-9006925
Platelet activation, signaling and aggregation R-HSA-76002
FLT3 signaling through SRC family kinases R-HSA-9706374
Interleukin-2 signaling R-HSA-9020558
Immune System R-HSA-168256
CD28 dependent PI3K/Akt signaling R-HSA-389357
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Host Interactions of HIV factors R-HSA-162909
RHOH GTPase cycle R-HSA-9013407
TCR signaling R-HSA-202403
Costimulation by the CD28 family R-HSA-388841
Signaling by KIT in disease R-HSA-9669938
DAP12 interactions R-HSA-2172127
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Cytokine Signaling in Immune system R-HSA-1280215
Nef and signal transduction R-HSA-164944
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
RHO GTPase cycle R-HSA-9012999
Interleukin-2 family signaling R-HSA-451927
Nef Mediated CD4 Down-regulation R-HSA-167590
Signaling by Rho GTPases R-HSA-194315
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
PD-1 signaling R-HSA-389948
PIP3 activates AKT signaling R-HSA-1257604
Regulation of KIT signaling R-HSA-1433559
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream TCR signaling R-HSA-202424
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
CD28 dependent Vav1 pathway R-HSA-389359
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by SCF-KIT R-HSA-1433557
FLT3 Signaling R-HSA-9607240
DAP12 signaling R-HSA-2424491
CTLA4 inhibitory signaling R-HSA-389513
PECAM1 interactions R-HSA-210990
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
RHO GTPase cycle R-HSA-9012999
Nef Mediated CD4 Down-regulation R-HSA-167590
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Infectious disease R-HSA-5663205
Signaling by SCF-KIT R-HSA-1433557
PIP3 activates AKT signaling R-HSA-1257604
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
PECAM1 interactions R-HSA-210990
FLT3 Signaling R-HSA-9607240
Intracellular signaling by second messengers R-HSA-9006925
Costimulation by the CD28 family R-HSA-388841
PD-1 signaling R-HSA-389948
Generation of second messenger molecules R-HSA-202433
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
RHOH GTPase cycle R-HSA-9013407
Adaptive Immune System R-HSA-1280218
Signaling by KIT in disease R-HSA-9669938
TCR signaling R-HSA-202403
DAP12 signaling R-HSA-2424491
Interleukin-2 family signaling R-HSA-451927
Innate Immune System R-HSA-168249
GPVI-mediated activation cascade R-HSA-114604
Signal Transduction R-HSA-162582
Downstream TCR signaling R-HSA-202424
CD28 dependent Vav1 pathway R-HSA-389359
Interleukin-2 signaling R-HSA-9020558
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
CD28 dependent PI3K/Akt signaling R-HSA-389357
CD28 co-stimulation R-HSA-389356
Hemostasis R-HSA-109582
Host Interactions of HIV factors R-HSA-162909
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cell surface interactions at the vascular wall R-HSA-202733
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Regulation of KIT signaling R-HSA-1433559
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
HIV Infection R-HSA-162906
Nef and signal transduction R-HSA-164944
FLT3 signaling through SRC family kinases R-HSA-9706374
CTLA4 inhibitory signaling R-HSA-389513
DAP12 interactions R-HSA-2172127
CTLA4 inhibitory signaling R-HSA-389513
CD28 dependent Vav1 pathway R-HSA-389359
Host Interactions of HIV factors R-HSA-162909
GPVI-mediated activation cascade R-HSA-114604
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
DAP12 interactions R-HSA-2172127
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by KIT in disease R-HSA-9669938
Nef Mediated CD4 Down-regulation R-HSA-167590
Hemostasis R-HSA-109582
RHOH GTPase cycle R-HSA-9013407
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Signal Transduction R-HSA-162582
DAP12 signaling R-HSA-2424491
Interleukin-2 family signaling R-HSA-451927
Intracellular signaling by second messengers R-HSA-9006925
PECAM1 interactions R-HSA-210990
PD-1 signaling R-HSA-389948
Interleukin-2 signaling R-HSA-9020558
Generation of second messenger molecules R-HSA-202433
FLT3 Signaling R-HSA-9607240
RHO GTPase cycle R-HSA-9012999
Adaptive Immune System R-HSA-1280218
Nef and signal transduction R-HSA-164944
CD28 dependent PI3K/Akt signaling R-HSA-389357
Regulation of KIT signaling R-HSA-1433559
HIV Infection R-HSA-162906
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
PI3K/AKT Signaling in Cancer R-HSA-2219528
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Cell surface interactions at the vascular wall R-HSA-202733
Innate Immune System R-HSA-168249
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream TCR signaling R-HSA-202424
Signaling by SCF-KIT R-HSA-1433557
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Interleukins R-HSA-449147
FLT3 signaling through SRC family kinases R-HSA-9706374
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
Disease R-HSA-1643685
Signaling by Rho GTPases R-HSA-194315
CD28 co-stimulation R-HSA-389356
Hemostasis R-HSA-109582
Interleukin-2 signaling R-HSA-9020558
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nef and signal transduction R-HSA-164944
CD28 co-stimulation R-HSA-389356
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Adaptive Immune System R-HSA-1280218
FLT3 signaling through SRC family kinases R-HSA-9706374
Signaling by SCF-KIT R-HSA-1433557
CTLA4 inhibitory signaling R-HSA-389513
Cell surface interactions at the vascular wall R-HSA-202733
HIV Infection R-HSA-162906
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPase cycle R-HSA-9012999
Costimulation by the CD28 family R-HSA-388841
Signaling by Interleukins R-HSA-449147
RHOH GTPase cycle R-HSA-9013407
GPVI-mediated activation cascade R-HSA-114604
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
Immune System R-HSA-168256
CD28 dependent Vav1 pathway R-HSA-389359
Negative regulation of the PI3K/AKT network R-HSA-199418
DAP12 signaling R-HSA-2424491
PECAM1 interactions R-HSA-210990
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream TCR signaling R-HSA-202424
Generation of second messenger molecules R-HSA-202433
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
TCR signaling R-HSA-202403
Regulation of KIT signaling R-HSA-1433559
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Signaling by KIT in disease R-HSA-9669938
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
FLT3 Signaling R-HSA-9607240
Signaling by Rho GTPases R-HSA-194315
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Interleukin-2 family signaling R-HSA-451927
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Nef Mediated CD4 Down-regulation R-HSA-167590
PD-1 signaling R-HSA-389948
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Innate Immune System R-HSA-168249
DAP12 interactions R-HSA-2172127
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
CD28 dependent Vav1 pathway R-HSA-389359
DAP12 interactions R-HSA-2172127
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Infectious disease R-HSA-5663205
Host Interactions of HIV factors R-HSA-162909
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
Interleukin-2 family signaling R-HSA-451927
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nef and signal transduction R-HSA-164944
Cell surface interactions at the vascular wall R-HSA-202733
Nef Mediated CD4 Down-regulation R-HSA-167590
PD-1 signaling R-HSA-389948
Signaling by SCF-KIT R-HSA-1433557
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signaling by KIT in disease R-HSA-9669938
GPVI-mediated activation cascade R-HSA-114604
HIV Infection R-HSA-162906
RHOH GTPase cycle R-HSA-9013407
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
PIP3 activates AKT signaling R-HSA-1257604
Regulation of KIT signaling R-HSA-1433559
FLT3 signaling through SRC family kinases R-HSA-9706374
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
PI3K/AKT Signaling in Cancer R-HSA-2219528
FLT3 Signaling R-HSA-9607240
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
Costimulation by the CD28 family R-HSA-388841
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Signaling by Interleukins R-HSA-449147
Signaling by Rho GTPases R-HSA-194315
Interleukin-2 signaling R-HSA-9020558
CTLA4 inhibitory signaling R-HSA-389513
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
CD28 dependent PI3K/Akt signaling R-HSA-389357
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
PECAM1 interactions R-HSA-210990
Generation of second messenger molecules R-HSA-202433
Cytokine Signaling in Immune system R-HSA-1280215
DAP12 signaling R-HSA-2424491
CD28 co-stimulation R-HSA-389356
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nef Mediated CD4 Down-regulation R-HSA-167590
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Cytokine Signaling in Immune system R-HSA-1280215
DAP12 interactions R-HSA-2172127
Nef and signal transduction R-HSA-164944
Negative regulation of the PI3K/AKT network R-HSA-199418
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
CD28 dependent PI3K/Akt signaling R-HSA-389357
GPVI-mediated activation cascade R-HSA-114604
RHO GTPase cycle R-HSA-9012999
DAP12 signaling R-HSA-2424491
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
FLT3 Signaling R-HSA-9607240
Cell surface interactions at the vascular wall R-HSA-202733
FLT3 signaling through SRC family kinases R-HSA-9706374
Adaptive Immune System R-HSA-1280218
Hemostasis R-HSA-109582
Signaling by Rho GTPases R-HSA-194315
Interleukin-2 family signaling R-HSA-451927
CD28 dependent Vav1 pathway R-HSA-389359
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
HIV Infection R-HSA-162906
Signaling by KIT in disease R-HSA-9669938
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
Interleukin-2 signaling R-HSA-9020558
PD-1 signaling R-HSA-389948
Generation of second messenger molecules R-HSA-202433
CD28 co-stimulation R-HSA-389356
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
PECAM1 interactions R-HSA-210990
RHOH GTPase cycle R-HSA-9013407
Downstream TCR signaling R-HSA-202424
Host Interactions of HIV factors R-HSA-162909
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Signaling by SCF-KIT R-HSA-1433557
Disease R-HSA-1643685
Costimulation by the CD28 family R-HSA-388841
CTLA4 inhibitory signaling R-HSA-389513
Immune System R-HSA-168256
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of KIT signaling R-HSA-1433559
DAP12 interactions R-HSA-2172127
Costimulation by the CD28 family R-HSA-388841
Cell surface interactions at the vascular wall R-HSA-202733
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
RHO GTPase cycle R-HSA-9012999
CTLA4 inhibitory signaling R-HSA-389513
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
Nef and signal transduction R-HSA-164944
Signaling by KIT in disease R-HSA-9669938
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
PD-1 signaling R-HSA-389948
Platelet activation, signaling and aggregation R-HSA-76002
Immune System R-HSA-168256
Signaling by SCF-KIT R-HSA-1433557
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
Regulation of KIT signaling R-HSA-1433559
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Interleukin-2 signaling R-HSA-9020558
Signal Transduction R-HSA-162582
HIV Infection R-HSA-162906
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Hemostasis R-HSA-109582
Generation of second messenger molecules R-HSA-202433
Intracellular signaling by second messengers R-HSA-9006925
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
Interleukin-2 family signaling R-HSA-451927
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
CD28 dependent Vav1 pathway R-HSA-389359
RHOH GTPase cycle R-HSA-9013407
Innate Immune System R-HSA-168249
FLT3 Signaling R-HSA-9607240
FLT3 signaling through SRC family kinases R-HSA-9706374
GPVI-mediated activation cascade R-HSA-114604
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Downstream TCR signaling R-HSA-202424
Nef Mediated CD4 Down-regulation R-HSA-167590
Host Interactions of HIV factors R-HSA-162909
CD28 co-stimulation R-HSA-389356
DAP12 signaling R-HSA-2424491
PECAM1 interactions R-HSA-210990
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream TCR signaling R-HSA-202424
GPVI-mediated activation cascade R-HSA-114604
Negative regulation of the PI3K/AKT network R-HSA-199418
Translocation of ZAP-70 to Immunological synapse R-HSA-202430
Signaling by SCF-KIT R-HSA-1433557
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Generation of second messenger molecules R-HSA-202433
CD28 dependent Vav1 pathway R-HSA-389359
Interleukin-2 family signaling R-HSA-451927
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by KIT in disease R-HSA-9669938
Cytokine Signaling in Immune system R-HSA-1280215
PI3K/AKT Signaling in Cancer R-HSA-2219528
DAP12 interactions R-HSA-2172127
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Immune System R-HSA-168256
FLT3 signaling through SRC family kinases R-HSA-9706374
Interleukin-2 signaling R-HSA-9020558
CTLA4 inhibitory signaling R-HSA-389513
PECAM1 interactions R-HSA-210990
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
CD28 co-stimulation R-HSA-389356
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell surface interactions at the vascular wall R-HSA-202733
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
HIV Infection R-HSA-162906
Signaling by Rho GTPases R-HSA-194315
Nef and signal transduction R-HSA-164944
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Interleukins R-HSA-449147
Costimulation by the CD28 family R-HSA-388841
Disease R-HSA-1643685
CD28 dependent PI3K/Akt signaling R-HSA-389357
Nef Mediated CD4 Down-regulation R-HSA-167590
FLT3 Signaling R-HSA-9607240
Regulation of KIT signaling R-HSA-1433559
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952
RHO GTPase cycle R-HSA-9012999
PD-1 signaling R-HSA-389948
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOH GTPase cycle R-HSA-9013407
TCR signaling R-HSA-202403
DAP12 signaling R-HSA-2424491

Expression Atlas ENSG00000182866
LRG display in Ensembl gene LRG_153
NCBI gene (formerly Entrezgene) 3932
GeneCards 6524
HGNC Symbol HGNC:6524
MIM gene 153390
MIM morbid 615758
UniProtKB Gene Name P06239
WikiGene 3932
Gene: PIK3R3
Ensembl ID : ENSG00000117461
Description: phosphoinositide-3-kinase regulatory subunit 3
Gene Synonyms: P55
26 APIs:
276 Possible Orthologues:

Metabolism of lipids R-HSA-556833
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Metabolism R-HSA-1430728
Phospholipid metabolism R-HSA-1483257
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
PI Metabolism R-HSA-1483255
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Axon guidance R-HSA-422475
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin receptor SHC signaling R-HSA-912526
Developmental Biology R-HSA-1266738
PI3K/AKT Signaling in Cancer R-HSA-2219528
Synthesis of PIPs at the plasma membrane R-HSA-1660499
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAC1 GTPase cycle R-HSA-9013149
PIP3 activates AKT signaling R-HSA-1257604
Signaling by SCF-KIT R-HSA-1433557
G alpha (q) signalling events R-HSA-416476
CD28 co-stimulation R-HSA-389356
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-7 signaling R-HSA-1266695
ESR-mediated signaling R-HSA-8939211
Signaling by GPCR R-HSA-372790
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Interleukin-2 family signaling R-HSA-451927
GPVI-mediated activation cascade R-HSA-114604
Adaptive Immune System R-HSA-1280218
Negative regulation of the PI3K/AKT network R-HSA-199418
RAC2 GTPase cycle R-HSA-9013404
RHO GTPase cycle R-HSA-9012999
Disease R-HSA-1643685
RET signaling R-HSA-8853659
Costimulation by the CD28 family R-HSA-388841
Regulation of signaling by CBL R-HSA-912631
CD28 dependent PI3K/Akt signaling R-HSA-389357
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by KIT in disease R-HSA-9669938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
CD28 co-stimulation R-HSA-389356
Signaling by GPCR R-HSA-372790
Interleukin receptor SHC signaling R-HSA-912526
Metabolism R-HSA-1430728
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G alpha (q) signalling events R-HSA-416476
RAC2 GTPase cycle R-HSA-9013404
Signaling by Nuclear Receptors R-HSA-9006931
GPVI-mediated activation cascade R-HSA-114604
PI Metabolism R-HSA-1483255
Interleukin-7 signaling R-HSA-1266695
GPCR downstream signalling R-HSA-388396
Extra-nuclear estrogen signaling R-HSA-9009391
Nervous system development R-HSA-9675108
Costimulation by the CD28 family R-HSA-388841
Signaling by KIT in disease R-HSA-9669938
Axon guidance R-HSA-422475
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
RHO GTPase cycle R-HSA-9012999
CD28 dependent PI3K/Akt signaling R-HSA-389357
Immune System R-HSA-168256
RET signaling R-HSA-8853659
PI3K/AKT Signaling in Cancer R-HSA-2219528
Hemostasis R-HSA-109582
RAC1 GTPase cycle R-HSA-9013149
Regulation of signaling by CBL R-HSA-912631
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by SCF-KIT R-HSA-1433557
PIP3 activates AKT signaling R-HSA-1257604
Phospholipid metabolism R-HSA-1483257
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of lipids R-HSA-556833
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Phospholipid metabolism R-HSA-1483257
Interleukin-7 signaling R-HSA-1266695
RAC1 GTPase cycle R-HSA-9013149
CD28 dependent PI3K/Akt signaling R-HSA-389357
Disease R-HSA-1643685
GPCR downstream signalling R-HSA-388396
ESR-mediated signaling R-HSA-8939211
Signaling by GPCR R-HSA-372790
PI Metabolism R-HSA-1483255
Costimulation by the CD28 family R-HSA-388841
Signaling by Nuclear Receptors R-HSA-9006931
Axon guidance R-HSA-422475
CD28 co-stimulation R-HSA-389356
Adaptive Immune System R-HSA-1280218
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
GPVI-mediated activation cascade R-HSA-114604
G alpha (q) signalling events R-HSA-416476
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Platelet activation, signaling and aggregation R-HSA-76002
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
Negative regulation of the PI3K/AKT network R-HSA-199418
RHO GTPase cycle R-HSA-9012999
Interleukin receptor SHC signaling R-HSA-912526
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by KIT in disease R-HSA-9669938
Signal Transduction R-HSA-162582
Metabolism of lipids R-HSA-556833
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Hemostasis R-HSA-109582
Regulation of signaling by CBL R-HSA-912631
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-2 family signaling R-HSA-451927
RAC2 GTPase cycle R-HSA-9013404
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RET signaling R-HSA-8853659
Signaling by SCF-KIT R-HSA-1433557
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Negative regulation of the PI3K/AKT network R-HSA-199418
Hemostasis R-HSA-109582
CD28 co-stimulation R-HSA-389356
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
GPCR downstream signalling R-HSA-388396
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by SCF-KIT R-HSA-1433557
Signaling by GPCR R-HSA-372790
RHO GTPase cycle R-HSA-9012999
Metabolism R-HSA-1430728
PI3K/AKT Signaling in Cancer R-HSA-2219528
RET signaling R-HSA-8853659
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Developmental Biology R-HSA-1266738
Signaling by KIT in disease R-HSA-9669938
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Phospholipid metabolism R-HSA-1483257
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Rho GTPases R-HSA-194315
Interleukin-2 family signaling R-HSA-451927
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
RAC2 GTPase cycle R-HSA-9013404
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Nervous system development R-HSA-9675108
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Interleukins R-HSA-449147
CD28 dependent PI3K/Akt signaling R-HSA-389357
Interleukin-7 signaling R-HSA-1266695
Axon guidance R-HSA-422475
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Metabolism of lipids R-HSA-556833
Regulation of signaling by CBL R-HSA-912631
ESR-mediated signaling R-HSA-8939211
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAC1 GTPase cycle R-HSA-9013149
PIP3 activates AKT signaling R-HSA-1257604
Phospholipid metabolism R-HSA-1483257
Signaling by Interleukins R-HSA-449147
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Interleukin receptor SHC signaling R-HSA-912526
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Interleukin-2 family signaling R-HSA-451927
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Signaling by SCF-KIT R-HSA-1433557
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-7 signaling R-HSA-1266695
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Hemostasis R-HSA-109582
Negative regulation of the PI3K/AKT network R-HSA-199418
RHO GTPase cycle R-HSA-9012999
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism R-HSA-1430728
Costimulation by the CD28 family R-HSA-388841
Signaling by Rho GTPases R-HSA-194315
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Signaling by Nuclear Receptors R-HSA-9006931
Intracellular signaling by second messengers R-HSA-9006925
Adaptive Immune System R-HSA-1280218
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by GPCR R-HSA-372790
CD28 co-stimulation R-HSA-389356
G alpha (q) signalling events R-HSA-416476
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
RAC2 GTPase cycle R-HSA-9013404
Developmental Biology R-HSA-1266738
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAC1 GTPase cycle R-HSA-9013149
Axon guidance R-HSA-422475
Metabolism of lipids R-HSA-556833
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
RET signaling R-HSA-8853659
PIP3 activates AKT signaling R-HSA-1257604
Regulation of signaling by CBL R-HSA-912631
Extra-nuclear estrogen signaling R-HSA-9009391
PI3K/AKT Signaling in Cancer R-HSA-2219528
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet activation, signaling and aggregation R-HSA-76002
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CD28 dependent PI3K/Akt signaling R-HSA-389357
RHO GTPase cycle R-HSA-9012999
Hemostasis R-HSA-109582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Metabolism of lipids R-HSA-556833
Disease R-HSA-1643685
RET signaling R-HSA-8853659
Phospholipid metabolism R-HSA-1483257
PI3K/AKT Signaling in Cancer R-HSA-2219528
GPVI-mediated activation cascade R-HSA-114604
PI Metabolism R-HSA-1483255
Adaptive Immune System R-HSA-1280218
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Nervous system development R-HSA-9675108
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAC2 GTPase cycle R-HSA-9013404
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of signaling by CBL R-HSA-912631
Interleukin-2 family signaling R-HSA-451927
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
CD28 co-stimulation R-HSA-389356
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Negative regulation of the PI3K/AKT network R-HSA-199418
Interleukin receptor SHC signaling R-HSA-912526
Signaling by SCF-KIT R-HSA-1433557
Interleukin-7 signaling R-HSA-1266695
Signaling by Interleukins R-HSA-449147
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Signaling by KIT in disease R-HSA-9669938
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Rho GTPases R-HSA-194315
ESR-mediated signaling R-HSA-8939211
RAC1 GTPase cycle R-HSA-9013149
Interleukin receptor SHC signaling R-HSA-912526
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RET signaling R-HSA-8853659
Hemostasis R-HSA-109582
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Metabolism of lipids R-HSA-556833
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHO GTPase cycle R-HSA-9012999
G alpha (q) signalling events R-HSA-416476
Axon guidance R-HSA-422475
Immune System R-HSA-168256
RAC1 GTPase cycle R-HSA-9013149
Signaling by Interleukins R-HSA-449147
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by SCF-KIT R-HSA-1433557
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Costimulation by the CD28 family R-HSA-388841
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CD28 co-stimulation R-HSA-389356
Intracellular signaling by second messengers R-HSA-9006925
Adaptive Immune System R-HSA-1280218
Phospholipid metabolism R-HSA-1483257
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by GPCR R-HSA-372790
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
GPCR downstream signalling R-HSA-388396
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-2 family signaling R-HSA-451927
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI Metabolism R-HSA-1483255
CD28 dependent PI3K/Akt signaling R-HSA-389357
RAC2 GTPase cycle R-HSA-9013404
Regulation of signaling by CBL R-HSA-912631
Interleukin-7 signaling R-HSA-1266695
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Immune System R-HSA-168256
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by KIT in disease R-HSA-9669938
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Costimulation by the CD28 family R-HSA-388841
PI Metabolism R-HSA-1483255
Signaling by GPCR R-HSA-372790
Interleukin-2 family signaling R-HSA-451927
Hemostasis R-HSA-109582
RHO GTPase cycle R-HSA-9012999
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin receptor SHC signaling R-HSA-912526
Regulation of signaling by CBL R-HSA-912631
Signal Transduction R-HSA-162582
Signaling by Nuclear Receptors R-HSA-9006931
Platelet activation, signaling and aggregation R-HSA-76002
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RAC2 GTPase cycle R-HSA-9013404
PI3K/AKT Signaling in Cancer R-HSA-2219528
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
CD28 co-stimulation R-HSA-389356
RET signaling R-HSA-8853659
G alpha (q) signalling events R-HSA-416476
Signaling by Interleukins R-HSA-449147
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RAC1 GTPase cycle R-HSA-9013149
Nervous system development R-HSA-9675108
Phospholipid metabolism R-HSA-1483257
Interleukin-7 signaling R-HSA-1266695
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Developmental Biology R-HSA-1266738
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
GPVI-mediated activation cascade R-HSA-114604
ESR-mediated signaling R-HSA-8939211
Adaptive Immune System R-HSA-1280218
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
GPCR downstream signalling R-HSA-388396
Interleukin-2 family signaling R-HSA-451927
Metabolism of lipids R-HSA-556833
Signaling by KIT in disease R-HSA-9669938
ESR-mediated signaling R-HSA-8939211
Metabolism R-HSA-1430728
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
G alpha (q) signalling events R-HSA-416476
Nervous system development R-HSA-9675108
Costimulation by the CD28 family R-HSA-388841
Phospholipid metabolism R-HSA-1483257
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RAC1 GTPase cycle R-HSA-9013149
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Hemostasis R-HSA-109582
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
GPCR downstream signalling R-HSA-388396
Interleukin receptor SHC signaling R-HSA-912526
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of signaling by CBL R-HSA-912631
RAC2 GTPase cycle R-HSA-9013404
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
PI Metabolism R-HSA-1483255
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
GPVI-mediated activation cascade R-HSA-114604
RHO GTPase cycle R-HSA-9012999
RET signaling R-HSA-8853659
CD28 co-stimulation R-HSA-389356
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI3K/AKT Signaling in Cancer R-HSA-2219528
Axon guidance R-HSA-422475
Interleukin-7 signaling R-HSA-1266695
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by SCF-KIT R-HSA-1433557
Intracellular signaling by second messengers R-HSA-9006925
RHO GTPase cycle R-HSA-9012999
Signaling by Interleukins R-HSA-449147
Interleukin-2 family signaling R-HSA-451927
Axon guidance R-HSA-422475
PI Metabolism R-HSA-1483255
Signaling by KIT in disease R-HSA-9669938
GPVI-mediated activation cascade R-HSA-114604
Negative regulation of the PI3K/AKT network R-HSA-199418
RAC2 GTPase cycle R-HSA-9013404
G alpha (q) signalling events R-HSA-416476
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Costimulation by the CD28 family R-HSA-388841
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Nuclear Receptors R-HSA-9006931
Interleukin-7 signaling R-HSA-1266695
Hemostasis R-HSA-109582
ESR-mediated signaling R-HSA-8939211
Adaptive Immune System R-HSA-1280218
GPCR downstream signalling R-HSA-388396
CD28 dependent PI3K/Akt signaling R-HSA-389357
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
RET signaling R-HSA-8853659
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Regulation of signaling by CBL R-HSA-912631
PIP3 activates AKT signaling R-HSA-1257604
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of lipids R-HSA-556833
RAC1 GTPase cycle R-HSA-9013149
Interleukin receptor SHC signaling R-HSA-912526
CD28 co-stimulation R-HSA-389356
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipid metabolism R-HSA-1483257

Expression Atlas ENSG00000117461
NCBI gene (formerly Entrezgene) 8503
GeneCards 8981
HGNC Symbol HGNC:8981
MIM gene 606076
UniProtKB Gene Name Q92569
WikiGene 8503
Gene: PIK3R1
Ensembl ID : ENSG00000145675
Description: phosphoinositide-3-kinase regulatory subunit 1
Gene Synonyms: GRB1,P85,P85-ALPHA,P85ALPHA
26 APIs:
259 Possible Orthologues:

Signaling by FGFR1 R-HSA-5654736
Disease R-HSA-1643685
Role of phospholipids in phagocytosis R-HSA-2029485
PI-3K cascade:FGFR3 R-HSA-5654710
RHO GTPase cycle R-HSA-9012999
Downstream signaling of activated FGFR2 R-HSA-5654696
Disease R-HSA-1643685
DAP12 interactions R-HSA-2172127
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by GPCR R-HSA-372790
Signaling by FGFR in disease R-HSA-1226099
RHOA GTPase cycle R-HSA-8980692
Cell-Cell communication R-HSA-1500931
Signaling by Nuclear Receptors R-HSA-9006931
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by EGFR R-HSA-177929
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RHOV GTPase cycle R-HSA-9013424
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB2 KD Mutants R-HSA-9664565
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Erythropoietin R-HSA-9006335
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFR in Cancer R-HSA-1643713
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by NTRK1 (TRKA) R-HSA-187037
Intracellular signaling by second messengers R-HSA-9006925
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RHOJ GTPase cycle R-HSA-9013409
Insulin receptor signalling cascade R-HSA-74751
Nervous system development R-HSA-9675108
PI-3K cascade:FGFR1 R-HSA-5654689
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
RND2 GTPase cycle R-HSA-9696270
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ESR-mediated signaling R-HSA-8939211
Nephrin family interactions R-HSA-373753
Signal Transduction R-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Adaptive Immune System R-HSA-1280218
Phospholipid metabolism R-HSA-1483257
Signaling by VEGF R-HSA-194138
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PIP3 activates AKT signaling R-HSA-1257604
Metabolism R-HSA-1430728
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Signaling by SCF-KIT R-HSA-1433557
RHOU GTPase cycle R-HSA-9013420
Extra-nuclear estrogen signaling R-HSA-9009391
Hemostasis R-HSA-109582
Interleukin receptor SHC signaling R-HSA-912526
RHOF GTPase cycle R-HSA-9035034
CD28 co-stimulation R-HSA-389356
RAC1 GTPase cycle R-HSA-9013149
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Regulation of signaling by CBL R-HSA-912631
Signaling by NTRKs R-HSA-166520
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by KIT in disease R-HSA-9669938
Interleukin-7 signaling R-HSA-1266695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by FGFR3 R-HSA-5654741
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
Downstream TCR signaling R-HSA-202424
RHOB GTPase cycle R-HSA-9013026
GPCR downstream signalling R-HSA-388396
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by EGFRvIII in Cancer R-HSA-5637812
PI Metabolism R-HSA-1483255
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR1 in disease R-HSA-5655302
GAB1 signalosome R-HSA-180292
Immune System R-HSA-168256
CD28 dependent PI3K/Akt signaling R-HSA-389357
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Metabolism of lipids R-HSA-556833
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by FLT3 fusion proteins R-HSA-9703465
Downstream signal transduction R-HSA-186763
Interleukin-2 family signaling R-HSA-451927
Signaling by ALK fusions and activated point mutants R-HSA-9725370
IGF1R signaling cascade R-HSA-2428924
PI3K/AKT Signaling in Cancer R-HSA-2219528
Costimulation by the CD28 family R-HSA-388841
Signaling by FGFR1 R-HSA-5654736
Activated NTRK3 signals through PI3K R-HSA-9603381
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR4 R-HSA-5654743
RND3 GTPase cycle R-HSA-9696264
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Downstream signaling of activated FGFR3 R-HSA-5654708
RET signaling R-HSA-8853659
Tie2 Signaling R-HSA-210993
Signaling by ERBB2 R-HSA-1227986
RHOC GTPase cycle R-HSA-9013106
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
IRS-mediated signalling R-HSA-112399
RND1 GTPase cycle R-HSA-9696273
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RHOD GTPase cycle R-HSA-9013405
CDC42 GTPase cycle R-HSA-9013148
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by Interleukins R-HSA-449147
FLT3 signaling in disease R-HSA-9682385
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by NTRK3 (TRKC) R-HSA-9034015
Constitutive Signaling by EGFRvIII R-HSA-5637810
GPVI-mediated activation cascade R-HSA-114604
Signaling by FGFR2 R-HSA-5654738
Signaling by ALK R-HSA-201556
PI3K events in ERBB2 signaling R-HSA-1963642
Axon guidance R-HSA-422475
DAP12 signaling R-HSA-2424491
FLT3 Signaling R-HSA-9607240
Downstream signaling of activated FGFR1 R-HSA-5654687
PI-3K cascade:FGFR4 R-HSA-5654720
TCR signaling R-HSA-202403
Signaling by MET R-HSA-6806834
Signaling by PDGFR in disease R-HSA-9671555
MET activates PI3K/AKT signaling R-HSA-8851907
Negative regulation of the PI3K/AKT network R-HSA-199418
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RAC3 GTPase cycle R-HSA-9013423
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by PDGF R-HSA-186797
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GP1b-IX-V activation signalling R-HSA-430116
Signaling by ERBB2 ECD mutants R-HSA-9665348
RAC2 GTPase cycle R-HSA-9013404
Signaling by Rho GTPases R-HSA-194315
RHOG GTPase cycle R-HSA-9013408
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT activation R-HSA-198203
Developmental Biology R-HSA-1266738
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by ALK in cancer R-HSA-9700206
Signaling by FGFR R-HSA-190236
Signaling by NTRK2 (TRKB) R-HSA-9006115
PI3K Cascade R-HSA-109704
Innate Immune System R-HSA-168249
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PI-3K cascade:FGFR2 R-HSA-5654695
RND3 GTPase cycle R-HSA-9696264
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Rho GTPases R-HSA-194315
Signaling by Erythropoietin R-HSA-9006335
RHOA GTPase cycle R-HSA-8980692
Signal Transduction R-HSA-162582
RAC2 GTPase cycle R-HSA-9013404
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RHOC GTPase cycle R-HSA-9013106
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Insulin receptor signalling cascade R-HSA-74751
Downstream signal transduction R-HSA-186763
Activated NTRK3 signals through PI3K R-HSA-9603381
RHOB GTPase cycle R-HSA-9013026
Signaling by FGFR1 in disease R-HSA-5655302
G alpha (q) signalling events R-HSA-416476
Signaling by FGFR in disease R-HSA-1226099
Regulation of signaling by CBL R-HSA-912631
Signaling by ALK in cancer R-HSA-9700206
Interleukin receptor SHC signaling R-HSA-912526
Signaling by NTRKs R-HSA-166520
Costimulation by the CD28 family R-HSA-388841
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by ERBB2 R-HSA-1227986
RHOD GTPase cycle R-HSA-9013405
Signaling by MET R-HSA-6806834
Developmental Biology R-HSA-1266738
Signaling by FLT3 fusion proteins R-HSA-9703465
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RHOV GTPase cycle R-HSA-9013424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 KD Mutants R-HSA-9664565
Downstream TCR signaling R-HSA-202424
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by EGFR R-HSA-177929
Signaling by FGFR4 R-HSA-5654743
Signaling by EGFRvIII in Cancer R-HSA-5637812
RAF/MAP kinase cascade R-HSA-5673001
ESR-mediated signaling R-HSA-8939211
Adaptive Immune System R-HSA-1280218
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by KIT in disease R-HSA-9669938
PI3K events in ERBB4 signaling R-HSA-1250342
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by VEGF R-HSA-194138
PI3K events in ERBB2 signaling R-HSA-1963642
DAP12 signaling R-HSA-2424491
CD28 co-stimulation R-HSA-389356
CDC42 GTPase cycle R-HSA-9013148
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by FGFR4 in disease R-HSA-5655291
RHOU GTPase cycle R-HSA-9013420
Signaling by FGFR3 R-HSA-5654741
PI-3K cascade:FGFR1 R-HSA-5654689
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by FGFR3 in disease R-HSA-5655332
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by PDGFR in disease R-HSA-9671555
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FLT3 Signaling R-HSA-9607240
PI3K/AKT activation R-HSA-198203
Signaling by ERBB4 R-HSA-1236394
RHOF GTPase cycle R-HSA-9035034
IRS-mediated signalling R-HSA-112399
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK family signaling cascades R-HSA-5683057
Interleukin-2 family signaling R-HSA-451927
MAPK1/MAPK3 signaling R-HSA-5684996
Cell-Cell communication R-HSA-1500931
Cytokine Signaling in Immune system R-HSA-1280215
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
VEGFA-VEGFR2 Pathway R-HSA-4420097
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHOG GTPase cycle R-HSA-9013408
PI3K Cascade R-HSA-109704
RAC3 GTPase cycle R-HSA-9013423
RHO GTPase cycle R-HSA-9012999
Tie2 Signaling R-HSA-210993
RAC1 GTPase cycle R-HSA-9013149
Interleukin-7 signaling R-HSA-1266695
CD28 dependent PI3K/Akt signaling R-HSA-389357
IRS-related events triggered by IGF1R R-HSA-2428928
Axon guidance R-HSA-422475
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by SCF-KIT R-HSA-1433557
RET signaling R-HSA-8853659
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
GP1b-IX-V activation signalling R-HSA-430116
Signaling by FGFR2 R-HSA-5654738
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by GPCR R-HSA-372790
RND1 GTPase cycle R-HSA-9696273
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR1 R-HSA-5654736
PI3K/AKT Signaling in Cancer R-HSA-2219528
GAB1 signalosome R-HSA-180292
Signaling by FGFR R-HSA-190236
GPVI-mediated activation cascade R-HSA-114604
Signaling by ERBB2 ECD mutants R-HSA-9665348
TCR signaling R-HSA-202403
Signaling by ALK R-HSA-201556
FLT3 signaling in disease R-HSA-9682385
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by NTRK3 (TRKC) R-HSA-9034015
Signaling by FGFR2 in disease R-HSA-5655253
PI Metabolism R-HSA-1483255
Disease R-HSA-1643685
Signaling by ERBB2 in Cancer R-HSA-1227990
GPCR downstream signalling R-HSA-388396
DAP12 interactions R-HSA-2172127
Signaling by Interleukins R-HSA-449147
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell surface interactions at the vascular wall R-HSA-202733
Hemostasis R-HSA-109582
IGF1R signaling cascade R-HSA-2428924
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by PDGF R-HSA-186797
RHOJ GTPase cycle R-HSA-9013409
Immune System R-HSA-168256
Nephrin family interactions R-HSA-373753
RND2 GTPase cycle R-HSA-9696270
Metabolism of lipids R-HSA-556833
Downstream signaling of activated FGFR1 R-HSA-5654687
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Activated NTRK2 signals through PI3K R-HSA-9028335
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by NTRK1 (TRKA) R-HSA-187037
Intracellular signaling by second messengers R-HSA-9006925
Phospholipid metabolism R-HSA-1483257
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream signaling of activated FGFR4 R-HSA-5654716
PI3K Cascade R-HSA-109704
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RAC1 GTPase cycle R-HSA-9013149
CD28 dependent PI3K/Akt signaling R-HSA-389357
Downstream signal transduction R-HSA-186763
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by FGFR in disease R-HSA-1226099
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
CD28 co-stimulation R-HSA-389356
PI Metabolism R-HSA-1483255
Cytokine Signaling in Immune system R-HSA-1280215
RHOD GTPase cycle R-HSA-9013405
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by Rho GTPases R-HSA-194315
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RHOV GTPase cycle R-HSA-9013424
Constitutive Signaling by EGFRvIII R-HSA-5637810
Metabolism of lipids R-HSA-556833
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signal Transduction R-HSA-162582
RHOG GTPase cycle R-HSA-9013408
Costimulation by the CD28 family R-HSA-388841
Signaling by SCF-KIT R-HSA-1433557
RND3 GTPase cycle R-HSA-9696264
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FLT3 fusion proteins R-HSA-9703465
RHOU GTPase cycle R-HSA-9013420
Regulation of signaling by CBL R-HSA-912631
Innate Immune System R-HSA-168249
Platelet activation, signaling and aggregation R-HSA-76002
MAPK family signaling cascades R-HSA-5683057
Nephrin family interactions R-HSA-373753
Signaling by ERBB2 in Cancer R-HSA-1227990
PI-3K cascade:FGFR4 R-HSA-5654720
RAF/MAP kinase cascade R-HSA-5673001
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
IRS-mediated signalling R-HSA-112399
PI-3K cascade:FGFR1 R-HSA-5654689
Developmental Biology R-HSA-1266738
Signaling by NTRK1 (TRKA) R-HSA-187037
IGF1R signaling cascade R-HSA-2428924
Signaling by EGFRvIII in Cancer R-HSA-5637812
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by ALK R-HSA-201556
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NTRKs R-HSA-166520
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by NTRK3 (TRKC) R-HSA-9034015
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by FGFR3 R-HSA-5654741
RAC2 GTPase cycle R-HSA-9013404
Signaling by GPCR R-HSA-372790
FLT3 Signaling R-HSA-9607240
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RET signaling R-HSA-8853659
RHOA GTPase cycle R-HSA-8980692
RHO GTPase cycle R-HSA-9012999
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 R-HSA-1227986
PI-3K cascade:FGFR3 R-HSA-5654710
Interleukin receptor SHC signaling R-HSA-912526
Signaling by ERBB4 R-HSA-1236394
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by FGFR2 R-HSA-5654738
Disease R-HSA-1643685
RHOF GTPase cycle R-HSA-9035034
TCR signaling R-HSA-202403
Signaling by Insulin receptor R-HSA-74752
Metabolism R-HSA-1430728
Signaling by FGFR R-HSA-190236
Signaling by KIT in disease R-HSA-9669938
Signaling by EGFR R-HSA-177929
Adaptive Immune System R-HSA-1280218
PI3K events in ERBB4 signaling R-HSA-1250342
Phospholipid metabolism R-HSA-1483257
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FLT3 signaling in disease R-HSA-9682385
Signaling by FGFR4 R-HSA-5654743
PI3K/AKT activation R-HSA-198203
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
RND1 GTPase cycle R-HSA-9696273
CDC42 GTPase cycle R-HSA-9013148
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
PI-3K cascade:FGFR2 R-HSA-5654695
Role of phospholipids in phagocytosis R-HSA-2029485
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Activated NTRK2 signals through PI3K R-HSA-9028335
Hemostasis R-HSA-109582
Insulin receptor signalling cascade R-HSA-74751
Signaling by Interleukins R-HSA-449147
Downstream signaling of activated FGFR3 R-HSA-5654708
ESR-mediated signaling R-HSA-8939211
Signaling by PDGFR in disease R-HSA-9671555
GPVI-mediated activation cascade R-HSA-114604
GPCR downstream signalling R-HSA-388396
RAC3 GTPase cycle R-HSA-9013423
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Activated NTRK3 signals through PI3K R-HSA-9603381
RHOB GTPase cycle R-HSA-9013026
DAP12 interactions R-HSA-2172127
Interleukin-7 signaling R-HSA-1266695
RND2 GTPase cycle R-HSA-9696270
RHOC GTPase cycle R-HSA-9013106
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by MET R-HSA-6806834
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
DAP12 signaling R-HSA-2424491
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-2 family signaling R-HSA-451927
Axon guidance R-HSA-422475
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RHOJ GTPase cycle R-HSA-9013409
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by PDGF R-HSA-186797
Nervous system development R-HSA-9675108
Cell-Cell communication R-HSA-1500931
GP1b-IX-V activation signalling R-HSA-430116
Downstream TCR signaling R-HSA-202424
Signaling by ERBB2 ECD mutants R-HSA-9665348
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Tie2 Signaling R-HSA-210993
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by Erythropoietin R-HSA-9006335
Signaling by Nuclear Receptors R-HSA-9006931
PIP3 activates AKT signaling R-HSA-1257604
Extra-nuclear estrogen signaling R-HSA-9009391
GAB1 signalosome R-HSA-180292
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ALK in cancer R-HSA-9700206
MET activates PI3K/AKT signaling R-HSA-8851907
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ERBB2 R-HSA-1227986
Signaling by FGFR1 R-HSA-5654736
Signaling by FLT3 fusion proteins R-HSA-9703465
Extra-nuclear estrogen signaling R-HSA-9009391
PI-3K cascade:FGFR1 R-HSA-5654689
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR4 R-HSA-5654720
Costimulation by the CD28 family R-HSA-388841
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ESR-mediated signaling R-HSA-8939211
RHOG GTPase cycle R-HSA-9013408
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ALK in cancer R-HSA-9700206
MAPK1/MAPK3 signaling R-HSA-5684996
RHOU GTPase cycle R-HSA-9013420
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RET signaling R-HSA-8853659
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Downstream signaling of activated FGFR1 R-HSA-5654687
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRS-related events triggered by IGF1R R-HSA-2428928
GPVI-mediated activation cascade R-HSA-114604
Signaling by Nuclear Receptors R-HSA-9006931
Immune System R-HSA-168256
GPCR downstream signalling R-HSA-388396
PI3K Cascade R-HSA-109704
Insulin receptor signalling cascade R-HSA-74751
Signaling by EGFRvIII in Cancer R-HSA-5637812
FGFR1 mutant receptor activation R-HSA-1839124
Cell surface interactions at the vascular wall R-HSA-202733
RHOJ GTPase cycle R-HSA-9013409
Axon guidance R-HSA-422475
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by FGFR2 R-HSA-5654738
G alpha (q) signalling events R-HSA-416476
RHOD GTPase cycle R-HSA-9013405
Signaling by NTRK3 (TRKC) R-HSA-9034015
PI Metabolism R-HSA-1483255
Signaling by FGFR3 R-HSA-5654741
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Signaling by Insulin receptor R-HSA-74752
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Developmental Biology R-HSA-1266738
Constitutive Signaling by EGFRvIII R-HSA-5637810
RAC2 GTPase cycle R-HSA-9013404
Downstream signaling of activated FGFR3 R-HSA-5654708
PI3K events in ERBB4 signaling R-HSA-1250342
RAC3 GTPase cycle R-HSA-9013423
PI-3K cascade:FGFR3 R-HSA-5654710
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Nephrin family interactions R-HSA-373753
PI3K/AKT activation R-HSA-198203
Signaling by EGFR R-HSA-177929
FLT3 Signaling R-HSA-9607240
Regulation of signaling by CBL R-HSA-912631
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream TCR signaling R-HSA-202424
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by NTRKs R-HSA-166520
FLT3 signaling in disease R-HSA-9682385
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
IRS-mediated signalling R-HSA-112399
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Tie2 Signaling R-HSA-210993
GAB1 signalosome R-HSA-180292
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by GPCR R-HSA-372790
Signaling by FGFR R-HSA-190236
Nervous system development R-HSA-9675108
Signaling by FGFR in disease R-HSA-1226099
Phospholipid metabolism R-HSA-1483257
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by KIT in disease R-HSA-9669938
Metabolism of lipids R-HSA-556833
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Interleukins R-HSA-449147
Signaling by NTRK2 (TRKB) R-HSA-9006115
Interleukin-2 family signaling R-HSA-451927
RHOC GTPase cycle R-HSA-9013106
Adaptive Immune System R-HSA-1280218
CDC42 GTPase cycle R-HSA-9013148
DAP12 interactions R-HSA-2172127
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
GP1b-IX-V activation signalling R-HSA-430116
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by PDGFR in disease R-HSA-9671555
MET activates PI3K/AKT signaling R-HSA-8851907
CD28 dependent PI3K/Akt signaling R-HSA-389357
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RHOV GTPase cycle R-HSA-9013424
RAC1 GTPase cycle R-HSA-9013149
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
RND3 GTPase cycle R-HSA-9696264
Signaling by NTRK1 (TRKA) R-HSA-187037
RND1 GTPase cycle R-HSA-9696273
RHO GTPase cycle R-HSA-9012999
Downstream signal transduction R-HSA-186763
Signaling by ERBB2 KD Mutants R-HSA-9664565
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by FGFR4 R-HSA-5654743
TCR signaling R-HSA-202403
Signaling by SCF-KIT R-HSA-1433557
Signaling by Erythropoietin R-HSA-9006335
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Synthesis of PIPs at the plasma membrane R-HSA-1660499
MAPK family signaling cascades R-HSA-5683057
Interleukin receptor SHC signaling R-HSA-912526
RHOB GTPase cycle R-HSA-9013026
RND2 GTPase cycle R-HSA-9696270
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cell-Cell communication R-HSA-1500931
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-7 signaling R-HSA-1266695
Signaling by MET R-HSA-6806834
RAF/MAP kinase cascade R-HSA-5673001
RHOA GTPase cycle R-HSA-8980692
DAP12 signaling R-HSA-2424491
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by FGFR4 in disease R-HSA-5655291
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
Signaling by FGFR3 in disease R-HSA-5655332
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases R-HSA-194315
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by VEGF R-HSA-194138
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ERBB4 R-HSA-1236394
CD28 co-stimulation R-HSA-389356
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by ALK R-HSA-201556
Metabolism R-HSA-1430728
RHOF GTPase cycle R-HSA-9035034
Signaling by PDGF R-HSA-186797
Signaling by ERBB2 R-HSA-1227986
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by PDGFR in disease R-HSA-9671555
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by NTRKs R-HSA-166520
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
IRS-related events triggered by IGF1R R-HSA-2428928
RHOJ GTPase cycle R-HSA-9013409
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR1 in disease R-HSA-5655302
GAB1 signalosome R-HSA-180292
Role of phospholipids in phagocytosis R-HSA-2029485
Downstream signaling of activated FGFR1 R-HSA-5654687
RHOU GTPase cycle R-HSA-9013420
GP1b-IX-V activation signalling R-HSA-430116
Signaling by EGFR R-HSA-177929
Tie2 Signaling R-HSA-210993
PI3K events in ERBB2 signaling R-HSA-1963642
DAP12 interactions R-HSA-2172127
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
GPCR downstream signalling R-HSA-388396
RAC2 GTPase cycle R-HSA-9013404
IGF1R signaling cascade R-HSA-2428924
RND2 GTPase cycle R-HSA-9696270
PI-3K cascade:FGFR4 R-HSA-5654720
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
PI3K Cascade R-HSA-109704
Signaling by VEGF R-HSA-194138
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Activated NTRK3 signals through PI3K R-HSA-9603381
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Downstream signaling of activated FGFR3 R-HSA-5654708
Interleukin receptor SHC signaling R-HSA-912526
Axon guidance R-HSA-422475
Signaling by FGFR R-HSA-190236
PI Metabolism R-HSA-1483255
RHOD GTPase cycle R-HSA-9013405
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
RAC1 GTPase cycle R-HSA-9013149
Signaling by FGFR4 R-HSA-5654743
Downstream signal transduction R-HSA-186763
Signaling by NTRK1 (TRKA) R-HSA-187037
IRS-mediated signalling R-HSA-112399
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Erythropoietin R-HSA-9006335
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by GPCR R-HSA-372790
Signaling by FGFR2 R-HSA-5654738
TCR signaling R-HSA-202403
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Signaling by FLT3 fusion proteins R-HSA-9703465
CDC42 GTPase cycle R-HSA-9013148
Immune System R-HSA-168256
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by FGFR3 R-HSA-5654741
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by KIT in disease R-HSA-9669938
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nephrin family interactions R-HSA-373753
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
RHOG GTPase cycle R-HSA-9013408
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by ERBB2 ECD mutants R-HSA-9665348
Developmental Biology R-HSA-1266738
FLT3 signaling in disease R-HSA-9682385
Signaling by ALK R-HSA-201556
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-7 signaling R-HSA-1266695
RHOA GTPase cycle R-HSA-8980692
Downstream TCR signaling R-HSA-202424
Innate Immune System R-HSA-168249
GPVI-mediated activation cascade R-HSA-114604
Costimulation by the CD28 family R-HSA-388841
RAC3 GTPase cycle R-HSA-9013423
DAP12 signaling R-HSA-2424491
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Rho GTPases R-HSA-194315
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by FGFR1 R-HSA-5654736
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by ERBB4 R-HSA-1236394
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downstream signaling of activated FGFR2 R-HSA-5654696
ESR-mediated signaling R-HSA-8939211
Metabolism of lipids R-HSA-556833
Signaling by FGFR2 in disease R-HSA-5655253
Regulation of signaling by CBL R-HSA-912631
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Extra-nuclear estrogen signaling R-HSA-9009391
Cytokine Signaling in Immune system R-HSA-1280215
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by Insulin receptor R-HSA-74752
Cell-Cell communication R-HSA-1500931
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Interleukin-2 family signaling R-HSA-451927
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by MET R-HSA-6806834
Constitutive Signaling by EGFRvIII R-HSA-5637810
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NTRK2 signals through PI3K R-HSA-9028335
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by FGFR in disease R-HSA-1226099
Signaling by NTRK3 (TRKC) R-HSA-9034015
PI3K/AKT activation R-HSA-198203
Adaptive Immune System R-HSA-1280218
RND3 GTPase cycle R-HSA-9696264
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by ERBB2 KD Mutants R-HSA-9664565
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by ALK in cancer R-HSA-9700206
RET signaling R-HSA-8853659
Phospholipid metabolism R-HSA-1483257
RHO GTPase cycle R-HSA-9012999
Signaling by Interleukins R-HSA-449147
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by FGFR3 in disease R-HSA-5655332
FLT3 Signaling R-HSA-9607240
CD28 co-stimulation R-HSA-389356
RHOV GTPase cycle R-HSA-9013424
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by NTRK2 (TRKB) R-HSA-9006115
RHOB GTPase cycle R-HSA-9013026
RHOF GTPase cycle R-HSA-9035034
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
RND1 GTPase cycle R-HSA-9696273
MET activates PI3K/AKT signaling R-HSA-8851907
Hemostasis R-HSA-109582
Signaling by Erythropoietin R-HSA-9006335
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by MET R-HSA-6806834
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by FLT3 fusion proteins R-HSA-9703465
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 KD Mutants R-HSA-9664565
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI-3K cascade:FGFR2 R-HSA-5654695
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHO GTPase cycle R-HSA-9012999
MET activates PI3K/AKT signaling R-HSA-8851907
Insulin receptor signalling cascade R-HSA-74751
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
CD28 co-stimulation R-HSA-389356
Signaling by FGFR3 in disease R-HSA-5655332
Immune System R-HSA-168256
Signaling by NTRKs R-HSA-166520
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin receptor SHC signaling R-HSA-912526
PI3K/AKT activation R-HSA-198203
Metabolism R-HSA-1430728
Signaling by ERBB2 R-HSA-1227986
DAP12 signaling R-HSA-2424491
RHOB GTPase cycle R-HSA-9013026
RHOG GTPase cycle R-HSA-9013408
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PIP3 activates AKT signaling R-HSA-1257604
DAP12 interactions R-HSA-2172127
Signaling by Rho GTPases R-HSA-194315
RAC1 GTPase cycle R-HSA-9013149
RHOV GTPase cycle R-HSA-9013424
Nephrin family interactions R-HSA-373753
IRS-related events triggered by IGF1R R-HSA-2428928
Innate Immune System R-HSA-168249
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
RHOF GTPase cycle R-HSA-9035034
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Costimulation by the CD28 family R-HSA-388841
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
PI3K/AKT Signaling in Cancer R-HSA-2219528
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by PDGFR in disease R-HSA-9671555
PI3K events in ERBB2 signaling R-HSA-1963642
Cytokine Signaling in Immune system R-HSA-1280215
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by KIT in disease R-HSA-9669938
Signaling by FGFR4 R-HSA-5654743
Signaling by Interleukins R-HSA-449147
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by NTRK3 (TRKC) R-HSA-9034015
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
PI Metabolism R-HSA-1483255
TCR signaling R-HSA-202403
Signaling by GPCR R-HSA-372790
RHOA GTPase cycle R-HSA-8980692
Downstream signal transduction R-HSA-186763
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by FGFR3 R-HSA-5654741
RHOD GTPase cycle R-HSA-9013405
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
MAPK family signaling cascades R-HSA-5683057
RAC2 GTPase cycle R-HSA-9013404
Phospholipid metabolism R-HSA-1483257
RND2 GTPase cycle R-HSA-9696270
CDC42 GTPase cycle R-HSA-9013148
Signaling by SCF-KIT R-HSA-1433557
ESR-mediated signaling R-HSA-8939211
Signaling by NTRK1 (TRKA) R-HSA-187037
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Axon guidance R-HSA-422475
Signaling by EGFR in Cancer R-HSA-1643713
PI3K Cascade R-HSA-109704
Signaling by FGFR R-HSA-190236
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Interleukin-7 signaling R-HSA-1266695
Negative regulation of the PI3K/AKT network R-HSA-199418
Metabolism of lipids R-HSA-556833
Interleukin-2 family signaling R-HSA-451927
IGF1R signaling cascade R-HSA-2428924
Signal Transduction R-HSA-162582
Regulation of signaling by CBL R-HSA-912631
Platelet activation, signaling and aggregation R-HSA-76002
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
RHOC GTPase cycle R-HSA-9013106
Signaling by ALK in cancer R-HSA-9700206
Downstream signaling of activated FGFR2 R-HSA-5654696
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by EGFRvIII in Cancer R-HSA-5637812
Cell-Cell communication R-HSA-1500931
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FLT3 signaling in disease R-HSA-9682385
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
G alpha (q) signalling events R-HSA-416476
Signaling by PDGF R-HSA-186797
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by FGFR2 in disease R-HSA-5655253
RND3 GTPase cycle R-HSA-9696264
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
CD28 dependent PI3K/Akt signaling R-HSA-389357
FLT3 Signaling R-HSA-9607240
Signaling by ALK R-HSA-201556
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by FGFR2 R-HSA-5654738
RET signaling R-HSA-8853659
RHOU GTPase cycle R-HSA-9013420
Downstream TCR signaling R-HSA-202424
PI-3K cascade:FGFR1 R-HSA-5654689
RHOJ GTPase cycle R-HSA-9013409
Role of phospholipids in phagocytosis R-HSA-2029485
GPCR downstream signalling R-HSA-388396
Signaling by Nuclear Receptors R-HSA-9006931
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by EGFR R-HSA-177929
IRS-mediated signalling R-HSA-112399
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
RAC3 GTPase cycle R-HSA-9013423
Signaling by FGFR1 R-HSA-5654736
Signaling by FGFR in disease R-HSA-1226099
Signaling by ERBB4 R-HSA-1236394
PI3K events in ERBB4 signaling R-HSA-1250342
RND1 GTPase cycle R-HSA-9696273
Activated NTRK2 signals through PI3K R-HSA-9028335
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Downstream signaling of activated FGFR1 R-HSA-5654687
GAB1 signalosome R-HSA-180292
Signaling by VEGF R-HSA-194138
Tie2 Signaling R-HSA-210993
GP1b-IX-V activation signalling R-HSA-430116
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by ERBB2 ECD mutants R-HSA-9665348
IRS-mediated signalling R-HSA-112399
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Interleukins R-HSA-449147
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Platelet activation, signaling and aggregation R-HSA-76002
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by FGFR in disease R-HSA-1226099
Signaling by VEGF R-HSA-194138
FGFR1 mutant receptor activation R-HSA-1839124
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
Downstream TCR signaling R-HSA-202424
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 R-HSA-5654743
RHOJ GTPase cycle R-HSA-9013409
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR4 in disease R-HSA-5655291
CD28 dependent PI3K/Akt signaling R-HSA-389357
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by EGFR in Cancer R-HSA-1643713
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by NTRK3 (TRKC) R-HSA-9034015
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI-3K cascade:FGFR2 R-HSA-5654695
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
TCR signaling R-HSA-202403
Downstream signaling of activated FGFR4 R-HSA-5654716
PI-3K cascade:FGFR3 R-HSA-5654710
Activated NTRK3 signals through PI3K R-HSA-9603381
RHOG GTPase cycle R-HSA-9013408
Metabolism of lipids R-HSA-556833
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Metabolism R-HSA-1430728
Signaling by KIT in disease R-HSA-9669938
Signaling by FLT3 fusion proteins R-HSA-9703465
RHOB GTPase cycle R-HSA-9013026
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FGFR1 R-HSA-5654736
Signaling by PDGFR in disease R-HSA-9671555
DAP12 interactions R-HSA-2172127
Nephrin family interactions R-HSA-373753
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by GPCR R-HSA-372790
Signaling by EGFRvIII in Cancer R-HSA-5637812
RHOF GTPase cycle R-HSA-9035034
Signaling by FGFR3 R-HSA-5654741
Regulation of signaling by CBL R-HSA-912631
Signaling by FGFR1 in disease R-HSA-5655302
PI-3K cascade:FGFR4 R-HSA-5654720
Intracellular signaling by second messengers R-HSA-9006925
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by ERBB2 KD Mutants R-HSA-9664565
RND3 GTPase cycle R-HSA-9696264
Developmental Biology R-HSA-1266738
GP1b-IX-V activation signalling R-HSA-430116
RHOV GTPase cycle R-HSA-9013424
Downstream signaling of activated FGFR1 R-HSA-5654687
MET activates PI3K/AKT signaling R-HSA-8851907
RHOU GTPase cycle R-HSA-9013420
G alpha (q) signalling events R-HSA-416476
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by EGFRvIII R-HSA-5637810
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RAC3 GTPase cycle R-HSA-9013423
Interleukin-7 signaling R-HSA-1266695
RHOA GTPase cycle R-HSA-8980692
GPCR downstream signalling R-HSA-388396
Signaling by FGFR2 in disease R-HSA-5655253
PI3K Cascade R-HSA-109704
PI3K/AKT activation R-HSA-198203
Insulin receptor signalling cascade R-HSA-74751
Nervous system development R-HSA-9675108
Signaling by Erythropoietin R-HSA-9006335
Signaling by Insulin receptor R-HSA-74752
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
FLT3 Signaling R-HSA-9607240
Signaling by ERBB2 R-HSA-1227986
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by Nuclear Receptors R-HSA-9006931
DAP12 signaling R-HSA-2424491
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
GAB1 signalosome R-HSA-180292
IGF1R signaling cascade R-HSA-2428924
CD28 co-stimulation R-HSA-389356
Phospholipid metabolism R-HSA-1483257
Signaling by FGFR R-HSA-190236
Adaptive Immune System R-HSA-1280218
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Rho GTPases R-HSA-194315
Signaling by EGFR R-HSA-177929
Cell surface interactions at the vascular wall R-HSA-202733
Extra-nuclear estrogen signaling R-HSA-9009391
RAC1 GTPase cycle R-HSA-9013149
CDC42 GTPase cycle R-HSA-9013148
Signaling by ERBB4 R-HSA-1236394
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RND1 GTPase cycle R-HSA-9696273
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Activated NTRK2 signals through PI3K R-HSA-9028335
RND2 GTPase cycle R-HSA-9696270
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NTRKs R-HSA-166520
VEGFA-VEGFR2 Pathway R-HSA-4420097
Immune System R-HSA-168256
Signaling by MET R-HSA-6806834
RHOD GTPase cycle R-HSA-9013405
Costimulation by the CD28 family R-HSA-388841
PI3K events in ERBB2 signaling R-HSA-1963642
RHOC GTPase cycle R-HSA-9013106
RET signaling R-HSA-8853659
Innate Immune System R-HSA-168249
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Downstream signal transduction R-HSA-186763
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
RAC2 GTPase cycle R-HSA-9013404
Signaling by ALK R-HSA-201556
Tie2 Signaling R-HSA-210993
Downstream signaling of activated FGFR3 R-HSA-5654708
FLT3 signaling in disease R-HSA-9682385
Signaling by ALK in cancer R-HSA-9700206
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by FGFR2 R-HSA-5654738
Interleukin receptor SHC signaling R-HSA-912526
Signal Transduction R-HSA-162582
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RHO GTPase cycle R-HSA-9012999
Signaling by NTRK2 (TRKB) R-HSA-9006115
Hemostasis R-HSA-109582
PI Metabolism R-HSA-1483255
PI-3K cascade:FGFR1 R-HSA-5654689
ESR-mediated signaling R-HSA-8939211
Signaling by ERBB2 in Cancer R-HSA-1227990
Cell-Cell communication R-HSA-1500931
Disease R-HSA-1643685
Interleukin-2 family signaling R-HSA-451927
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Downstream signal transduction R-HSA-186763
MAPK family signaling cascades R-HSA-5683057
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by ERBB2 KD Mutants R-HSA-9664565
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by Rho GTPases R-HSA-194315
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by PDGF R-HSA-186797
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by VEGF R-HSA-194138
MET activates PI3K/AKT signaling R-HSA-8851907
CDC42 GTPase cycle R-HSA-9013148
PI-3K cascade:FGFR2 R-HSA-5654695
RHOJ GTPase cycle R-HSA-9013409
RHOG GTPase cycle R-HSA-9013408
Signaling by Erythropoietin R-HSA-9006335
Signaling by GPCR R-HSA-372790
Signaling by ERBB2 R-HSA-1227986
RAC2 GTPase cycle R-HSA-9013404
Signaling by ERBB2 ECD mutants R-HSA-9665348
Phospholipid metabolism R-HSA-1483257
RHOV GTPase cycle R-HSA-9013424
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Costimulation by the CD28 family R-HSA-388841
Signaling by ERBB2 in Cancer R-HSA-1227990
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
PI Metabolism R-HSA-1483255
Signaling by PDGFR in disease R-HSA-9671555
PI-3K cascade:FGFR4 R-HSA-5654720
Hemostasis R-HSA-109582
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by NTRK3 (TRKC) R-HSA-9034015
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by FGFR2 in disease R-HSA-5655253
RHOB GTPase cycle R-HSA-9013026
TCR signaling R-HSA-202403
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRK2 (TRKB) R-HSA-9006115
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by ALK R-HSA-201556
Signaling by FGFR R-HSA-190236
Signaling by FGFR1 R-HSA-5654736
Interleukin-7 signaling R-HSA-1266695
RAC3 GTPase cycle R-HSA-9013423
Regulation of signaling by CBL R-HSA-912631
Signaling by Nuclear Receptors R-HSA-9006931
Extra-nuclear estrogen signaling R-HSA-9009391
RHOF GTPase cycle R-HSA-9035034
IRS-related events triggered by IGF1R R-HSA-2428928
G alpha (q) signalling events R-HSA-416476
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by KIT in disease R-HSA-9669938
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Interleukin-2 family signaling R-HSA-451927
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by ALK in cancer R-HSA-9700206
RHOC GTPase cycle R-HSA-9013106
DAP12 interactions R-HSA-2172127
Signaling by FGFR3 R-HSA-5654741
Signaling by EGFR R-HSA-177929
VEGFA-VEGFR2 Pathway R-HSA-4420097
FLT3 Signaling R-HSA-9607240
RAC1 GTPase cycle R-HSA-9013149
Tie2 Signaling R-HSA-210993
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FLT3 fusion proteins R-HSA-9703465
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by EGFR in Cancer R-HSA-1643713
PI3K Cascade R-HSA-109704
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FGFR1 mutant receptor activation R-HSA-1839124
Immune System R-HSA-168256
Metabolism R-HSA-1430728
IRS-mediated signalling R-HSA-112399
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
RND1 GTPase cycle R-HSA-9696273
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Interleukin receptor SHC signaling R-HSA-912526
Signaling by NTRKs R-HSA-166520
Nephrin family interactions R-HSA-373753
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Role of phospholipids in phagocytosis R-HSA-2029485
CD28 co-stimulation R-HSA-389356
MAPK1/MAPK3 signaling R-HSA-5684996
RND3 GTPase cycle R-HSA-9696264
Signaling by FGFR in disease R-HSA-1226099
Signaling by SCF-KIT R-HSA-1433557
PI3K events in ERBB4 signaling R-HSA-1250342
RHOD GTPase cycle R-HSA-9013405
GP1b-IX-V activation signalling R-HSA-430116
RHO GTPase cycle R-HSA-9012999
PI-3K cascade:FGFR1 R-HSA-5654689
Activated NTRK3 signals through PI3K R-HSA-9603381
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
PI3K/AKT activation R-HSA-198203
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by MET R-HSA-6806834
Constitutive Signaling by EGFRvIII R-HSA-5637810
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Axon guidance R-HSA-422475
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by FGFR4 R-HSA-5654743
RHOA GTPase cycle R-HSA-8980692
RHOU GTPase cycle R-HSA-9013420
Activated NTRK2 signals through PI3K R-HSA-9028335
RET signaling R-HSA-8853659
Nervous system development R-HSA-9675108
Cell-Cell communication R-HSA-1500931
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of lipids R-HSA-556833
FLT3 signaling in disease R-HSA-9682385
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR2 R-HSA-5654738
Adaptive Immune System R-HSA-1280218
GPCR downstream signalling R-HSA-388396
Downstream TCR signaling R-HSA-202424
GAB1 signalosome R-HSA-180292
DAP12 signaling R-HSA-2424491
RND2 GTPase cycle R-HSA-9696270
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by Insulin receptor R-HSA-74752
Signaling by ERBB4 R-HSA-1236394
Signaling by FGFR3 in disease R-HSA-5655332
Developmental Biology R-HSA-1266738
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FLT3 fusion proteins R-HSA-9703465
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Metabolism R-HSA-1430728
Signaling by ERBB2 KD Mutants R-HSA-9664565
Axon guidance R-HSA-422475
Nephrin family interactions R-HSA-373753
Immune System R-HSA-168256
Costimulation by the CD28 family R-HSA-388841
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR3 R-HSA-5654710
Disease R-HSA-1643685
TCR signaling R-HSA-202403
VEGFA-VEGFR2 Pathway R-HSA-4420097
Interleukin-7 signaling R-HSA-1266695
Phospholipid metabolism R-HSA-1483257
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by PDGFR in disease R-HSA-9671555
Downstream signaling of activated FGFR2 R-HSA-5654696
DAP12 interactions R-HSA-2172127
Developmental Biology R-HSA-1266738
Constitutive Signaling by EGFRvIII R-HSA-5637810
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by KIT in disease R-HSA-9669938
Adaptive Immune System R-HSA-1280218
Signaling by FGFR1 in disease R-HSA-5655302
Cell-Cell communication R-HSA-1500931
ESR-mediated signaling R-HSA-8939211
PI3K Cascade R-HSA-109704
Interleukin-2 family signaling R-HSA-451927
RHOV GTPase cycle R-HSA-9013424
RHOU GTPase cycle R-HSA-9013420
Negative regulation of the PI3K/AKT network R-HSA-199418
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR3 R-HSA-5654741
Extra-nuclear estrogen signaling R-HSA-9009391
RHOA GTPase cycle R-HSA-8980692
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CDC42 GTPase cycle R-HSA-9013148
Signaling by MET R-HSA-6806834
FLT3 Signaling R-HSA-9607240
RAC2 GTPase cycle R-HSA-9013404
PIP3 activates AKT signaling R-HSA-1257604
G alpha (q) signalling events R-HSA-416476
Downstream signaling of activated FGFR3 R-HSA-5654708
PI3K events in ERBB4 signaling R-HSA-1250342
Metabolism of lipids R-HSA-556833
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by NTRK3 (TRKC) R-HSA-9034015
Interleukin receptor SHC signaling R-HSA-912526
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGF R-HSA-186797
DAP12 signaling R-HSA-2424491
Signaling by EGFR R-HSA-177929
Cytokine Signaling in Immune system R-HSA-1280215
RHOF GTPase cycle R-HSA-9035034
Signaling by EGFRvIII in Cancer R-HSA-5637812
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by NTRKs R-HSA-166520
RND3 GTPase cycle R-HSA-9696264
Activated NTRK2 signals through PI3K R-HSA-9028335
CD28 co-stimulation R-HSA-389356
Signaling by Insulin receptor R-HSA-74752
Signaling by NTRK2 (TRKB) R-HSA-9006115
Downstream signaling of activated FGFR4 R-HSA-5654716
RAC3 GTPase cycle R-HSA-9013423
Signaling by FGFR in disease R-HSA-1226099
Regulation of signaling by CBL R-HSA-912631
Signaling by ERBB2 ECD mutants R-HSA-9665348
Role of phospholipids in phagocytosis R-HSA-2029485
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by FGFR4 in disease R-HSA-5655291
Tie2 Signaling R-HSA-210993
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PI3K events in ERBB2 signaling R-HSA-1963642
RET signaling R-HSA-8853659
MAPK family signaling cascades R-HSA-5683057
RHOC GTPase cycle R-HSA-9013106
Signaling by FGFR R-HSA-190236
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by ALK R-HSA-201556
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by FGFR2 R-HSA-5654738
Signaling by ERBB2 R-HSA-1227986
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FLT3 signaling in disease R-HSA-9682385
GPCR downstream signalling R-HSA-388396
MAPK1/MAPK3 signaling R-HSA-5684996
RHOJ GTPase cycle R-HSA-9013409
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by FGFR3 in disease R-HSA-5655332
Platelet activation, signaling and aggregation R-HSA-76002
RHOB GTPase cycle R-HSA-9013026
Hemostasis R-HSA-109582
PI Metabolism R-HSA-1483255
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by ALK in cancer R-HSA-9700206
PI3K/AKT activation R-HSA-198203
RAC1 GTPase cycle R-HSA-9013149
Downstream TCR signaling R-HSA-202424
RHO GTPase cycle R-HSA-9012999
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GP1b-IX-V activation signalling R-HSA-430116
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB4 R-HSA-1236394
RND2 GTPase cycle R-HSA-9696270
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
RHOG GTPase cycle R-HSA-9013408
Signaling by GPCR R-HSA-372790
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Nervous system development R-HSA-9675108
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MET activates PI3K/AKT signaling R-HSA-8851907
Insulin receptor signalling cascade R-HSA-74751
RHOD GTPase cycle R-HSA-9013405
Signaling by FGFR1 R-HSA-5654736
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI-3K cascade:FGFR1 R-HSA-5654689
Signal Transduction R-HSA-162582
RND1 GTPase cycle R-HSA-9696273
Cell surface interactions at the vascular wall R-HSA-202733
RAF/MAP kinase cascade R-HSA-5673001
Downstream signal transduction R-HSA-186763
PI-3K cascade:FGFR2 R-HSA-5654695
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI-3K cascade:FGFR4 R-HSA-5654720
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by VEGF R-HSA-194138
Signaling by Erythropoietin R-HSA-9006335
IRS-mediated signalling R-HSA-112399
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
GPVI-mediated activation cascade R-HSA-114604
GAB1 signalosome R-HSA-180292
Intracellular signaling by second messengers R-HSA-9006925
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Constitutive Signaling by EGFRvIII R-HSA-5637810
RHOJ GTPase cycle R-HSA-9013409
Axon guidance R-HSA-422475
Signaling by PDGFR in disease R-HSA-9671555
RHOG GTPase cycle R-HSA-9013408
PI-3K cascade:FGFR3 R-HSA-5654710
Interleukin receptor SHC signaling R-HSA-912526
Innate Immune System R-HSA-168249
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ALK R-HSA-201556
GP1b-IX-V activation signalling R-HSA-430116
RHOD GTPase cycle R-HSA-9013405
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Insulin receptor signalling cascade R-HSA-74751
Signaling by KIT in disease R-HSA-9669938
Disease R-HSA-1643685
RHOB GTPase cycle R-HSA-9013026
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by FGFR2 R-HSA-5654738
RAC3 GTPase cycle R-HSA-9013423
G alpha (q) signalling events R-HSA-416476
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Interleukins R-HSA-449147
Costimulation by the CD28 family R-HSA-388841
Signaling by FGFR3 R-HSA-5654741
Interleukin-2 family signaling R-HSA-451927
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
FLT3 signaling in disease R-HSA-9682385
Adaptive Immune System R-HSA-1280218
DAP12 signaling R-HSA-2424491
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI-3K cascade:FGFR4 R-HSA-5654720
FLT3 Signaling R-HSA-9607240
RND1 GTPase cycle R-HSA-9696273
Nephrin family interactions R-HSA-373753
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Rho GTPases R-HSA-194315
Signaling by ERBB4 R-HSA-1236394
IGF1R signaling cascade R-HSA-2428924
RHOA GTPase cycle R-HSA-8980692
PI3K events in ERBB4 signaling R-HSA-1250342
ESR-mediated signaling R-HSA-8939211
Cell surface interactions at the vascular wall R-HSA-202733
RAC2 GTPase cycle R-HSA-9013404
GPCR downstream signalling R-HSA-388396
Signaling by Insulin receptor R-HSA-74752
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PI Metabolism R-HSA-1483255
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RAC1 GTPase cycle R-HSA-9013149
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling of activated FGFR4 R-HSA-5654716
Tie2 Signaling R-HSA-210993
Signaling by GPCR R-HSA-372790
Metabolism of lipids R-HSA-556833
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by FGFR R-HSA-190236
Signaling by PDGF R-HSA-186797
Developmental Biology R-HSA-1266738
Interleukin-7 signaling R-HSA-1266695
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR1 R-HSA-5654736
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
PI3K/AKT activation R-HSA-198203
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by FGFR3 in disease R-HSA-5655332
Phospholipid metabolism R-HSA-1483257
Signaling by FGFR4 in disease R-HSA-5655291
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downstream signaling of activated FGFR1 R-HSA-5654687
Negative regulation of the PI3K/AKT network R-HSA-199418
CD28 dependent PI3K/Akt signaling R-HSA-389357
Intracellular signaling by second messengers R-HSA-9006925
GPVI-mediated activation cascade R-HSA-114604
Signaling by MET R-HSA-6806834
RHOV GTPase cycle R-HSA-9013424
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR2 in disease R-HSA-5655253
Downstream TCR signaling R-HSA-202424
Cell-Cell communication R-HSA-1500931
Signaling by ERBB2 R-HSA-1227986
RHOF GTPase cycle R-HSA-9035034
Signaling by SCF-KIT R-HSA-1433557
Immune System R-HSA-168256
Metabolism R-HSA-1430728
TCR signaling R-HSA-202403
DAP12 interactions R-HSA-2172127
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
IRS-mediated signalling R-HSA-112399
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Erythropoietin R-HSA-9006335
RND3 GTPase cycle R-HSA-9696264
Signaling by FGFR in disease R-HSA-1226099
VEGFA-VEGFR2 Pathway R-HSA-4420097
Role of phospholipids in phagocytosis R-HSA-2029485
PI3K Cascade R-HSA-109704
RHO GTPase cycle R-HSA-9012999
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by NTRK3 (TRKC) R-HSA-9034015
MAPK family signaling cascades R-HSA-5683057
RHOU GTPase cycle R-HSA-9013420
FGFR1 mutant receptor activation R-HSA-1839124
Hemostasis R-HSA-109582
Signaling by ERBB2 in Cancer R-HSA-1227990
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by EGFR R-HSA-177929
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by NTRKs R-HSA-166520
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
GAB1 signalosome R-HSA-180292
MET activates PI3K/AKT signaling R-HSA-8851907
RHOC GTPase cycle R-HSA-9013106
Regulation of signaling by CBL R-HSA-912631
RND2 GTPase cycle R-HSA-9696270
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Cytokine Signaling in Immune system R-HSA-1280215
PI3K events in ERBB2 signaling R-HSA-1963642
Nervous system development R-HSA-9675108
CD28 co-stimulation R-HSA-389356
IRS-related events triggered by IGF1R R-HSA-2428928
Downstream signal transduction R-HSA-186763
Signaling by ALK in cancer R-HSA-9700206
RET signaling R-HSA-8853659
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR1 in disease R-HSA-5655302
CDC42 GTPase cycle R-HSA-9013148
Signaling by VEGF R-HSA-194138
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet activation, signaling and aggregation R-HSA-76002

Expression Atlas ENSG00000145675
LRG display in Ensembl gene LRG_453
NCBI gene (formerly Entrezgene) 5295
GeneCards 8979
HGNC Symbol HGNC:8979
MIM gene 171833
MIM morbid 616005
UniProtKB Gene Name P27986
WikiGene 5295
Gene: ATR
Ensembl ID : ENSG00000175054
Description: ATR serine/threonine kinase
Gene Synonyms: FRP1,MEC1,SCKL,SCKL1
4 APIs:
207 Possible Orthologues:

Disease R-HSA-1643685
Cell Cycle Checkpoints R-HSA-69620
Cellular response to heat stress R-HSA-3371556
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Transcriptional Regulation by TP53 R-HSA-3700989
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Diseases of DNA repair R-HSA-9675135
DNA Repair R-HSA-73894
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Disease R-HSA-1643685
Cellular responses to stimuli R-HSA-8953897
Fanconi Anemia Pathway R-HSA-6783310
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Meiotic synapsis R-HSA-1221632
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
G2/M Checkpoints R-HSA-69481
HDR through Homologous Recombination (HRR) R-HSA-5685942
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
G2/M DNA damage checkpoint R-HSA-69473
Processing of DNA double-strand break ends R-HSA-5693607
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
DNA Double-Strand Break Repair R-HSA-5693532
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Reproduction R-HSA-1474165
Meiosis R-HSA-1500620
Activation of ATR in response to replication stress R-HSA-176187
Homology Directed Repair R-HSA-5693538
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stress R-HSA-2262752
Cell Cycle R-HSA-1640170
DNA Repair R-HSA-73894
G2/M DNA damage checkpoint R-HSA-69473
Reproduction R-HSA-1474165
Meiosis R-HSA-1500620
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Homology Directed Repair R-HSA-5693538
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Fanconi Anemia Pathway R-HSA-6783310
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Regulation of HSF1-mediated heat shock response R-HSA-3371453
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
HDR through Homologous Recombination (HRR) R-HSA-5685942
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Processing of DNA double-strand break ends R-HSA-5693607
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Regulation of TP53 Activity R-HSA-5633007
DNA Double-Strand Break Repair R-HSA-5693532
Cell Cycle Checkpoints R-HSA-69620
Disease R-HSA-1643685
Meiotic synapsis R-HSA-1221632
Transcriptional Regulation by TP53 R-HSA-3700989
G2/M Checkpoints R-HSA-69481
Activation of ATR in response to replication stress R-HSA-176187
Diseases of DNA repair R-HSA-9675135
Cellular responses to stimuli R-HSA-8953897
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Cellular response to heat stress R-HSA-3371556
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Regulation of HSF1-mediated heat shock response R-HSA-3371453
HDR through Homologous Recombination (HRR) R-HSA-5685942
Reproduction R-HSA-1474165
Fanconi Anemia Pathway R-HSA-6783310
Homology Directed Repair R-HSA-5693538
Cellular response to heat stress R-HSA-3371556
Activation of ATR in response to replication stress R-HSA-176187
Processing of DNA double-strand break ends R-HSA-5693607
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
G2/M DNA damage checkpoint R-HSA-69473
Diseases of DNA repair R-HSA-9675135
Meiotic synapsis R-HSA-1221632
DNA Double-Strand Break Repair R-HSA-5693532
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Meiosis R-HSA-1500620
Gene expression (Transcription) R-HSA-74160
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Cell Cycle R-HSA-1640170
DNA Repair R-HSA-73894
G2/M Checkpoints R-HSA-69481
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Repair R-HSA-73894
G2/M Checkpoints R-HSA-69481
Homology Directed Repair R-HSA-5693538
Processing of DNA double-strand break ends R-HSA-5693607
HDR through Homologous Recombination (HRR) R-HSA-5685942
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
Fanconi Anemia Pathway R-HSA-6783310
RNA Polymerase II Transcription R-HSA-73857
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Meiosis R-HSA-1500620
DNA Double-Strand Break Repair R-HSA-5693532
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Meiotic synapsis R-HSA-1221632
Cellular responses to stimuli R-HSA-8953897
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular response to heat stress R-HSA-3371556
Reproduction R-HSA-1474165
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Impaired BRCA2 binding to RAD51 R-HSA-9709570
G2/M DNA damage checkpoint R-HSA-69473
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Diseases of DNA repair R-HSA-9675135
Activation of ATR in response to replication stress R-HSA-176187
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stress R-HSA-2262752
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
RNA Polymerase II Transcription R-HSA-73857
Homology Directed Repair R-HSA-5693538
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Disease R-HSA-1643685
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Processing of DNA double-strand break ends R-HSA-5693607
G2/M DNA damage checkpoint R-HSA-69473
Fanconi Anemia Pathway R-HSA-6783310
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Cell Cycle Checkpoints R-HSA-69620
Transcriptional Regulation by TP53 R-HSA-3700989
Activation of ATR in response to replication stress R-HSA-176187
DNA Repair R-HSA-73894
Diseases of DNA repair R-HSA-9675135
DNA Double-Strand Break Repair R-HSA-5693532
Cellular responses to stimuli R-HSA-8953897
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Regulation of TP53 Activity R-HSA-5633007
Meiosis R-HSA-1500620
Generic Transcription Pathway R-HSA-212436
Reproduction R-HSA-1474165
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Cellular response to heat stress R-HSA-3371556
HDR through Homologous Recombination (HRR) R-HSA-5685942
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Meiotic synapsis R-HSA-1221632
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Gene expression (Transcription) R-HSA-74160
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Processing of DNA double-strand break ends R-HSA-5693607
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Activation of ATR in response to replication stress R-HSA-176187
Diseases of DNA repair R-HSA-9675135
Cell Cycle Checkpoints R-HSA-69620
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
G2/M DNA damage checkpoint R-HSA-69473
Meiosis R-HSA-1500620
HDR through Homologous Recombination (HRR) R-HSA-5685942
Cell Cycle R-HSA-1640170
DNA Repair R-HSA-73894
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Fanconi Anemia Pathway R-HSA-6783310
Cellular responses to stimuli R-HSA-8953897
Meiotic synapsis R-HSA-1221632
DNA Double-Strand Break Repair R-HSA-5693532
Homology Directed Repair R-HSA-5693538
Reproduction R-HSA-1474165
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity R-HSA-5633007
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cellular response to heat stress R-HSA-3371556
Transcriptional Regulation by TP53 R-HSA-3700989
HDR through Single Strand Annealing (SSA) R-HSA-5685938
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Cellular responses to stress R-HSA-2262752
Activation of ATR in response to replication stress R-HSA-176187
G2/M DNA damage checkpoint R-HSA-69473
Gene expression (Transcription) R-HSA-74160
Meiotic synapsis R-HSA-1221632
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
DNA Repair R-HSA-73894
DNA Double-Strand Break Repair R-HSA-5693532
Cellular response to heat stress R-HSA-3371556
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Homology Directed Repair R-HSA-5693538
Regulation of TP53 Activity R-HSA-5633007
Cell Cycle Checkpoints R-HSA-69620
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Reproduction R-HSA-1474165
Fanconi Anemia Pathway R-HSA-6783310
Generic Transcription Pathway R-HSA-212436
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Meiosis R-HSA-1500620
Diseases of DNA repair R-HSA-9675135
HDR through Homologous Recombination (HRR) R-HSA-5685942
Processing of DNA double-strand break ends R-HSA-5693607
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Cellular responses to stress R-HSA-2262752
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Regulation of TP53 Activity R-HSA-5633007
Diseases of DNA repair R-HSA-9675135
G2/M DNA damage checkpoint R-HSA-69473
Homology Directed Repair R-HSA-5693538
Processing of DNA double-strand break ends R-HSA-5693607
Fanconi Anemia Pathway R-HSA-6783310
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double-Strand Break Repair R-HSA-5693532
Generic Transcription Pathway R-HSA-212436
Activation of ATR in response to replication stress R-HSA-176187
Regulation of HSF1-mediated heat shock response R-HSA-3371453
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Meiotic synapsis R-HSA-1221632
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
Cellular response to heat stress R-HSA-3371556
Meiosis R-HSA-1500620
Reproduction R-HSA-1474165
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
HDR through Homologous Recombination (HRR) R-HSA-5685942
Cell Cycle R-HSA-1640170
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Gene expression (Transcription) R-HSA-74160
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Meiosis R-HSA-1500620
Fanconi Anemia Pathway R-HSA-6783310
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Diseases of DNA repair R-HSA-9675135
Activation of ATR in response to replication stress R-HSA-176187
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
Reproduction R-HSA-1474165
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
G2/M DNA damage checkpoint R-HSA-69473
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
HDR through Single Strand Annealing (SSA) R-HSA-5685938
DNA Repair R-HSA-73894
Meiotic synapsis R-HSA-1221632
Cellular response to heat stress R-HSA-3371556
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Cellular responses to stimuli R-HSA-8953897
RNA Polymerase II Transcription R-HSA-73857
Homology Directed Repair R-HSA-5693538
HDR through Homologous Recombination (HRR) R-HSA-5685942
Processing of DNA double-strand break ends R-HSA-5693607
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
G2/M Checkpoints R-HSA-69481
DNA Double-Strand Break Repair R-HSA-5693532
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Cellular response to heat stress R-HSA-3371556
Gene expression (Transcription) R-HSA-74160
Meiotic synapsis R-HSA-1221632
Cell Cycle R-HSA-1640170
Cellular responses to stress R-HSA-2262752
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Cell Cycle Checkpoints R-HSA-69620
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Diseases of DNA repair R-HSA-9675135
Cellular responses to stimuli R-HSA-8953897
Processing of DNA double-strand break ends R-HSA-5693607
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Impaired BRCA2 binding to RAD51 R-HSA-9709570
G2/M DNA damage checkpoint R-HSA-69473
DNA Repair R-HSA-73894
Disease R-HSA-1643685
Regulation of TP53 Activity R-HSA-5633007
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Activation of ATR in response to replication stress R-HSA-176187
G2/M Checkpoints R-HSA-69481
Meiosis R-HSA-1500620
Reproduction R-HSA-1474165
HDR through Homologous Recombination (HRR) R-HSA-5685942
Generic Transcription Pathway R-HSA-212436
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional Regulation by TP53 R-HSA-3700989
HDR through Single Strand Annealing (SSA) R-HSA-5685938
RNA Polymerase II Transcription R-HSA-73857
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Homology Directed Repair R-HSA-5693538
Fanconi Anemia Pathway R-HSA-6783310
Homology Directed Repair R-HSA-5693538
Fanconi Anemia Pathway R-HSA-6783310
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Meiosis R-HSA-1500620
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle Checkpoints R-HSA-69620
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Regulation of TP53 Activity R-HSA-5633007
Activation of ATR in response to replication stress R-HSA-176187
Cellular response to heat stress R-HSA-3371556
HDR through Homologous Recombination (HRR) R-HSA-5685942
Gene expression (Transcription) R-HSA-74160
Processing of DNA double-strand break ends R-HSA-5693607
Reproduction R-HSA-1474165
G2/M Checkpoints R-HSA-69481
Diseases of DNA repair R-HSA-9675135
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Meiotic synapsis R-HSA-1221632
DNA Repair R-HSA-73894
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Disease R-HSA-1643685
Regulation of HSF1-mediated heat shock response R-HSA-3371453
DNA Double-Strand Break Repair R-HSA-5693532
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989

Expression Atlas ENSG00000175054
LRG display in Ensembl gene LRG_1403
NCBI gene (formerly Entrezgene) 545
GeneCards 882
HGNC Symbol HGNC:882
MIM gene 601215
MIM morbid 614564
UniProtKB Gene Name Q13535
WikiGene 545
Gene: AKT2
Ensembl ID : ENSG00000105221
Description: AKT serine/threonine kinase 2
Gene Synonyms: PKBB
14 APIs:
257 Possible Orthologues:

Cell Cycle R-HSA-1640170
Regulation of TP53 Expression and Degradation R-HSA-6806003
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AKT-mediated inactivation of FOXO1A R-HSA-211163
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
Downregulation of ERBB2 signaling R-HSA-8863795
Immune System R-HSA-168256
Activation of BH3-only proteins R-HSA-114452
VEGFR2 mediated vascular permeability R-HSA-5218920
S Phase R-HSA-69242
Cellular responses to stress R-HSA-2262752
Signaling by ERBB2 R-HSA-1227986
Cyclin E associated events during G1/S transition R-HSA-69202
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
AKT phosphorylates targets in the cytosol R-HSA-198323
Adaptive Immune System R-HSA-1280218
Regulation of PTEN stability and activity R-HSA-8948751
SARS-CoV-2 Infection R-HSA-9694516
GPCR downstream signalling R-HSA-388396
FLT3 Signaling R-HSA-9607240
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Intracellular signaling by second messengers R-HSA-9006925
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by GPCR R-HSA-372790
CTLA4 inhibitory signaling R-HSA-389513
Insulin receptor signalling cascade R-HSA-74751
PDE3B signalling R-HSA-165160
CD28 co-stimulation R-HSA-389356
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
IRS-related events triggered by IGF1R R-HSA-2428928
Regulation of TP53 Activity R-HSA-5633007
G-protein beta:gamma signalling R-HSA-397795
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Cell Cycle, Mitotic R-HSA-69278
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of beta-cell development R-HSA-186712
Activation of BAD and translocation to mitochondria R-HSA-111447
CD28 dependent PI3K/Akt signaling R-HSA-389357
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by WNT R-HSA-195721
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Membrane Trafficking R-HSA-199991
FOXO-mediated transcription R-HSA-9614085
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Nuclear Receptors R-HSA-9006931
SARS-CoV Infections R-HSA-9679506
Apoptosis R-HSA-109581
Disease R-HSA-1643685
TP53 Regulates Metabolic Genes R-HSA-5628897
Extra-nuclear estrogen signaling R-HSA-9009391
PI3K Cascade R-HSA-109704
Regulation of gene expression in beta cells R-HSA-210745
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by VEGF R-HSA-194138
Vesicle-mediated transport R-HSA-5653656
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of localization of FOXO transcription factors R-HSA-9614399
Transcriptional Regulation by TP53 R-HSA-3700989
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
AKT phosphorylates targets in the nucleus R-HSA-198693
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Signal Transduction R-HSA-162582
PTEN Regulation R-HSA-6807070
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Cellular responses to stimuli R-HSA-8953897
Activation of AKT2 R-HSA-165158
Developmental Biology R-HSA-1266738
SARS-CoV-2-host interactions R-HSA-9705683
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Signaling by Insulin receptor R-HSA-74752
Costimulation by the CD28 family R-HSA-388841
Inhibition of TSC complex formation by PKB R-HSA-165181
RNA Polymerase II Transcription R-HSA-73857
PKB-mediated events R-HSA-109703
Regulation of TP53 Degradation R-HSA-6804757
MTOR signalling R-HSA-165159
Rab regulation of trafficking R-HSA-9007101
IGF1R signaling cascade R-HSA-2428924
Transcriptional regulation by RUNX2 R-HSA-8878166
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
ESR-mediated signaling R-HSA-8939211
G1/S Transition R-HSA-69206
IRS-mediated signalling R-HSA-112399
VEGFA-VEGFR2 Pathway R-HSA-4420097
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of beta-cell development R-HSA-186712
Signal Transduction R-HSA-162582
IRS-mediated signalling R-HSA-112399
Activation of BH3-only proteins R-HSA-114452
MTOR signalling R-HSA-165159
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Intracellular signaling by second messengers R-HSA-9006925
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
Apoptosis R-HSA-109581
PI3K Cascade R-HSA-109704
Regulation of TP53 Degradation R-HSA-6804757
G-protein beta:gamma signalling R-HSA-397795
Signaling by VEGF R-HSA-194138
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Expression and Degradation R-HSA-6806003
Costimulation by the CD28 family R-HSA-388841
SARS-CoV Infections R-HSA-9679506
Extra-nuclear estrogen signaling R-HSA-9009391
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Signaling by GPCR R-HSA-372790
CD28 dependent PI3K/Akt signaling R-HSA-389357
Disease R-HSA-1643685
VEGFA-VEGFR2 Pathway R-HSA-4420097
Mitotic G1 phase and G1/S transition R-HSA-453279
IRS-related events triggered by IGF1R R-HSA-2428928
IGF1R signaling cascade R-HSA-2428924
FLT3 Signaling R-HSA-9607240
Cell Cycle R-HSA-1640170
Activation of AKT2 R-HSA-165158
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CD28 co-stimulation R-HSA-389356
AKT phosphorylates targets in the cytosol R-HSA-198323
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
TP53 Regulates Metabolic Genes R-HSA-5628897
Adaptive Immune System R-HSA-1280218
PDE3B signalling R-HSA-165160
SARS-CoV-2 Infection R-HSA-9694516
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
PTEN Regulation R-HSA-6807070
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Cytokine Signaling in Immune system R-HSA-1280215
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by ERBB2 R-HSA-1227986
Developmental Biology R-HSA-1266738
VEGFR2 mediated vascular permeability R-HSA-5218920
Rab regulation of trafficking R-HSA-9007101
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of TP53 Activity R-HSA-5633007
Downregulation of ERBB2 signaling R-HSA-8863795
PKB-mediated events R-HSA-109703
Regulation of localization of FOXO transcription factors R-HSA-9614399
Insulin receptor signalling cascade R-HSA-74751
RNA Polymerase II Transcription R-HSA-73857
Signaling by WNT R-HSA-195721
Vesicle-mediated transport R-HSA-5653656
AKT phosphorylates targets in the nucleus R-HSA-198693
Negative regulation of the PI3K/AKT network R-HSA-199418
GPCR downstream signalling R-HSA-388396
Gene expression (Transcription) R-HSA-74160
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Regulation of PTEN stability and activity R-HSA-8948751
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Programmed Cell Death R-HSA-5357801
AKT-mediated inactivation of FOXO1A R-HSA-211163
Membrane Trafficking R-HSA-199991
Inhibition of TSC complex formation by PKB R-HSA-165181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cellular responses to stress R-HSA-2262752
SARS-CoV-2-host interactions R-HSA-9705683
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of gene expression in beta cells R-HSA-210745
Generic Transcription Pathway R-HSA-212436
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Activation of BAD and translocation to mitochondria R-HSA-111447
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
FOXO-mediated transcription R-HSA-9614085
Cellular response to chemical stress R-HSA-9711123
CTLA4 inhibitory signaling R-HSA-389513
TCF dependent signaling in response to WNT R-HSA-201681
Membrane Trafficking R-HSA-199991
Cell Cycle, Mitotic R-HSA-69278
Signaling by ERBB2 R-HSA-1227986
Cyclin E associated events during G1/S transition R-HSA-69202
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
G-protein beta:gamma signalling R-HSA-397795
AKT-mediated inactivation of FOXO1A R-HSA-211163
IRS-mediated signalling R-HSA-112399
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-2-host interactions R-HSA-9705683
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Insulin receptor R-HSA-74752
G beta:gamma signalling through PI3Kgamma R-HSA-392451
CTLA4 inhibitory signaling R-HSA-389513
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCF dependent signaling in response to WNT R-HSA-201681
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
FOXO-mediated transcription R-HSA-9614085
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular response to chemical stress R-HSA-9711123
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
TP53 Regulates Metabolic Genes R-HSA-5628897
PI3K Cascade R-HSA-109704
Regulation of gene expression in beta cells R-HSA-210745
Vesicle-mediated transport R-HSA-5653656
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Downregulation of ERBB2 signaling R-HSA-8863795
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
SARS-CoV-2 Infection R-HSA-9694516
Activation of AKT2 R-HSA-165158
Signaling by VEGF R-HSA-194138
Rab regulation of trafficking R-HSA-9007101
Intrinsic Pathway for Apoptosis R-HSA-109606
PKB-mediated events R-HSA-109703
IGF1R signaling cascade R-HSA-2428924
Cellular responses to stimuli R-HSA-8953897
VEGFA-VEGFR2 Pathway R-HSA-4420097
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Negative regulation of the PI3K/AKT network R-HSA-199418
Cytokine Signaling in Immune system R-HSA-1280215
MTOR signalling R-HSA-165159
Regulation of TP53 Activity through Acetylation R-HSA-6804758
IRS-related events triggered by IGF1R R-HSA-2428928
Costimulation by the CD28 family R-HSA-388841
G1/S Transition R-HSA-69206
Regulation of TP53 Degradation R-HSA-6804757
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Gene expression (Transcription) R-HSA-74160
Activation of BH3-only proteins R-HSA-114452
Signaling by GPCR R-HSA-372790
Regulation of PTEN stability and activity R-HSA-8948751
AKT phosphorylates targets in the nucleus R-HSA-198693
VEGFR2 mediated vascular permeability R-HSA-5218920
SARS-CoV Infections R-HSA-9679506
Cell Cycle R-HSA-1640170
Inhibition of TSC complex formation by PKB R-HSA-165181
GPCR downstream signalling R-HSA-388396
Programmed Cell Death R-HSA-5357801
FLT3 Signaling R-HSA-9607240
Adaptive Immune System R-HSA-1280218
CD28 dependent PI3K/Akt signaling R-HSA-389357
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Regulation of TP53 Expression and Degradation R-HSA-6806003
AKT phosphorylates targets in the cytosol R-HSA-198323
PTEN Regulation R-HSA-6807070
Infectious disease R-HSA-5663205
Regulation of localization of FOXO transcription factors R-HSA-9614399
RNA Polymerase II Transcription R-HSA-73857
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of TP53 Activity R-HSA-5633007
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Transcriptional regulation by RUNX2 R-HSA-8878166
S Phase R-HSA-69242
Regulation of beta-cell development R-HSA-186712
Signaling by Nuclear Receptors R-HSA-9006931
Insulin receptor signalling cascade R-HSA-74751
CD28 co-stimulation R-HSA-389356
PDE3B signalling R-HSA-165160
ESR-mediated signaling R-HSA-8939211
Activation of BAD and translocation to mitochondria R-HSA-111447
Mitotic G1 phase and G1/S transition R-HSA-453279
TP53 Regulates Metabolic Genes R-HSA-5628897
Insulin receptor signalling cascade R-HSA-74751
Rab regulation of trafficking R-HSA-9007101
MTOR signalling R-HSA-165159
Regulation of localization of FOXO transcription factors R-HSA-9614399
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Transcriptional Regulation by TP53 R-HSA-3700989
Membrane Trafficking R-HSA-199991
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by WNT R-HSA-195721
Regulation of TP53 Expression and Degradation R-HSA-6806003
CD28 co-stimulation R-HSA-389356
G-protein beta:gamma signalling R-HSA-397795
Regulation of PTEN stability and activity R-HSA-8948751
CD28 dependent PI3K/Akt signaling R-HSA-389357
Negative regulation of the PI3K/AKT network R-HSA-199418
Infectious disease R-HSA-5663205
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
SARS-CoV-2-host interactions R-HSA-9705683
Cellular responses to stimuli R-HSA-8953897
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Insulin receptor R-HSA-74752
RNA Polymerase II Transcription R-HSA-73857
VEGFA-VEGFR2 Pathway R-HSA-4420097
PI3K/AKT Signaling in Cancer R-HSA-2219528
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
IGF1R signaling cascade R-HSA-2428924
CTLA4 inhibitory signaling R-HSA-389513
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Cytokine Signaling in Immune system R-HSA-1280215
PKB-mediated events R-HSA-109703
Gene expression (Transcription) R-HSA-74160
PI3K Cascade R-HSA-109704
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of beta-cell development R-HSA-186712
SARS-CoV-2 Infection R-HSA-9694516
Cellular response to chemical stress R-HSA-9711123
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Activation of BH3-only proteins R-HSA-114452
SARS-CoV Infections R-HSA-9679506
FLT3 Signaling R-HSA-9607240
Intrinsic Pathway for Apoptosis R-HSA-109606
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
AKT phosphorylates targets in the nucleus R-HSA-198693
Signaling by ERBB2 R-HSA-1227986
PTEN Regulation R-HSA-6807070
FOXO-mediated transcription R-HSA-9614085
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
S Phase R-HSA-69242
Costimulation by the CD28 family R-HSA-388841
Cellular responses to stress R-HSA-2262752
Activation of BAD and translocation to mitochondria R-HSA-111447
Developmental Biology R-HSA-1266738
Downregulation of ERBB2 signaling R-HSA-8863795
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
G1/S Transition R-HSA-69206
AKT phosphorylates targets in the cytosol R-HSA-198323
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
G beta:gamma signalling through PI3Kgamma R-HSA-392451
PDE3B signalling R-HSA-165160
Cyclin E associated events during G1/S transition R-HSA-69202
Vesicle-mediated transport R-HSA-5653656
Activation of AKT2 R-HSA-165158
AKT-mediated inactivation of FOXO1A R-HSA-211163
Signaling by Nuclear Receptors R-HSA-9006931
IRS-related events triggered by IGF1R R-HSA-2428928
Apoptosis R-HSA-109581
Inhibition of TSC complex formation by PKB R-HSA-165181
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Regulation of gene expression in beta cells R-HSA-210745
PIP3 activates AKT signaling R-HSA-1257604
ESR-mediated signaling R-HSA-8939211
Signaling by GPCR R-HSA-372790
Mitotic G1 phase and G1/S transition R-HSA-453279
IRS-mediated signalling R-HSA-112399
Signaling by VEGF R-HSA-194138
CTLA4 inhibitory signaling R-HSA-389513
IRS-related events triggered by IGF1R R-HSA-2428928
SARS-CoV-2 Infection R-HSA-9694516
CD28 dependent PI3K/Akt signaling R-HSA-389357
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
IRS-mediated signalling R-HSA-112399
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
Downregulation of ERBB2 signaling R-HSA-8863795
S Phase R-HSA-69242
Intracellular signaling by second messengers R-HSA-9006925
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
IGF1R signaling cascade R-HSA-2428924
Insulin receptor signalling cascade R-HSA-74751
Regulation of TP53 Activity R-HSA-5633007
PI3K/AKT Signaling in Cancer R-HSA-2219528
G1/S Transition R-HSA-69206
Rab regulation of trafficking R-HSA-9007101
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of AKT2 R-HSA-165158
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX2 R-HSA-8878166
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Extra-nuclear estrogen signaling R-HSA-9009391
Transcriptional Regulation by TP53 R-HSA-3700989
Disease R-HSA-1643685
AKT-mediated inactivation of FOXO1A R-HSA-211163
VEGFR2 mediated vascular permeability R-HSA-5218920
G-protein beta:gamma signalling R-HSA-397795
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
PDE3B signalling R-HSA-165160
AKT phosphorylates targets in the cytosol R-HSA-198323
Signaling by Insulin receptor R-HSA-74752
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FLT3 Signaling R-HSA-9607240
PI3K Cascade R-HSA-109704
Membrane Trafficking R-HSA-199991
ESR-mediated signaling R-HSA-8939211
Programmed Cell Death R-HSA-5357801
CD28 co-stimulation R-HSA-389356
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by VEGF R-HSA-194138
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle R-HSA-1640170
Cellular response to chemical stress R-HSA-9711123
PTEN Regulation R-HSA-6807070
Regulation of localization of FOXO transcription factors R-HSA-9614399
Negative regulation of the PI3K/AKT network R-HSA-199418
GPCR downstream signalling R-HSA-388396
SARS-CoV-2-host interactions R-HSA-9705683
PKB-mediated events R-HSA-109703
AKT phosphorylates targets in the nucleus R-HSA-198693
Signaling by GPCR R-HSA-372790
Activation of BAD and translocation to mitochondria R-HSA-111447
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of TP53 Degradation R-HSA-6804757
Inhibition of TSC complex formation by PKB R-HSA-165181
Developmental Biology R-HSA-1266738
TP53 Regulates Metabolic Genes R-HSA-5628897
Vesicle-mediated transport R-HSA-5653656
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Costimulation by the CD28 family R-HSA-388841
Regulation of gene expression in beta cells R-HSA-210745
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
MTOR signalling R-HSA-165159
Cell Cycle, Mitotic R-HSA-69278
FOXO-mediated transcription R-HSA-9614085
Regulation of beta-cell development R-HSA-186712
SARS-CoV Infections R-HSA-9679506
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of BH3-only proteins R-HSA-114452
Infectious disease R-HSA-5663205
Adaptive Immune System R-HSA-1280218
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by ERBB2 R-HSA-1227986
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cellular responses to stress R-HSA-2262752
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
Regulation of PTEN stability and activity R-HSA-8948751
G1/S Transition R-HSA-69206
Adaptive Immune System R-HSA-1280218
Signaling by Nuclear Receptors R-HSA-9006931
Rab regulation of trafficking R-HSA-9007101
IGF1R signaling cascade R-HSA-2428924
Mitotic G1 phase and G1/S transition R-HSA-453279
PTEN Regulation R-HSA-6807070
Regulation of TP53 Expression and Degradation R-HSA-6806003
Inhibition of TSC complex formation by PKB R-HSA-165181
PKB-mediated events R-HSA-109703
MTOR signalling R-HSA-165159
Downregulation of ERBB2 signaling R-HSA-8863795
Generic Transcription Pathway R-HSA-212436
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Cellular responses to stress R-HSA-2262752
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional Regulation by TP53 R-HSA-3700989
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Membrane Trafficking R-HSA-199991
Immune System R-HSA-168256
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
IRS-mediated signalling R-HSA-112399
PI3K Cascade R-HSA-109704
Apoptosis R-HSA-109581
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by WNT R-HSA-195721
PI3K/AKT Signaling in Cancer R-HSA-2219528
Costimulation by the CD28 family R-HSA-388841
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Regulation of PTEN stability and activity R-HSA-8948751
Intrinsic Pathway for Apoptosis R-HSA-109606
PIP3 activates AKT signaling R-HSA-1257604
GPCR downstream signalling R-HSA-388396
Programmed Cell Death R-HSA-5357801
Intracellular signaling by second messengers R-HSA-9006925
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
SARS-CoV-2 Infection R-HSA-9694516
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Infectious disease R-HSA-5663205
Activation of AKT2 R-HSA-165158
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Vesicle-mediated transport R-HSA-5653656
Cellular responses to stimuli R-HSA-8953897
G-protein beta:gamma signalling R-HSA-397795
SARS-CoV Infections R-HSA-9679506
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Insulin receptor R-HSA-74752
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ERBB2 R-HSA-1227986
Cell Cycle R-HSA-1640170
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
VEGFR2 mediated vascular permeability R-HSA-5218920
Regulation of localization of FOXO transcription factors R-HSA-9614399
Activation of BAD and translocation to mitochondria R-HSA-111447
KEAP1-NFE2L2 pathway R-HSA-9755511
CD28 dependent PI3K/Akt signaling R-HSA-389357
SARS-CoV-2-host interactions R-HSA-9705683
IRS-related events triggered by IGF1R R-HSA-2428928
FLT3 Signaling R-HSA-9607240
TP53 Regulates Metabolic Genes R-HSA-5628897
CD28 co-stimulation R-HSA-389356
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by GPCR R-HSA-372790
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to chemical stress R-HSA-9711123
RNA Polymerase II Transcription R-HSA-73857
Regulation of beta-cell development R-HSA-186712
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Activation of BH3-only proteins R-HSA-114452
TCF dependent signaling in response to WNT R-HSA-201681
Extra-nuclear estrogen signaling R-HSA-9009391
AKT phosphorylates targets in the cytosol R-HSA-198323
FOXO-mediated transcription R-HSA-9614085
Signaling by VEGF R-HSA-194138
CTLA4 inhibitory signaling R-HSA-389513
AKT phosphorylates targets in the nucleus R-HSA-198693
ESR-mediated signaling R-HSA-8939211
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of TP53 Activity R-HSA-5633007
S Phase R-HSA-69242
Regulation of gene expression in beta cells R-HSA-210745
Regulation of TP53 Degradation R-HSA-6804757
AKT-mediated inactivation of FOXO1A R-HSA-211163
Cell Cycle, Mitotic R-HSA-69278
Insulin receptor signalling cascade R-HSA-74751
PDE3B signalling R-HSA-165160
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of gene expression in beta cells R-HSA-210745
Signaling by WNT R-HSA-195721
Activation of AKT2 R-HSA-165158
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Nuclear Receptors R-HSA-9006931
G1/S Transition R-HSA-69206
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
VEGFR2 mediated vascular permeability R-HSA-5218920
Apoptosis R-HSA-109581
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Regulation of localization of FOXO transcription factors R-HSA-9614399
IRS-mediated signalling R-HSA-112399
MTOR signalling R-HSA-165159
Signal Transduction R-HSA-162582
Activation of BAD and translocation to mitochondria R-HSA-111447
KEAP1-NFE2L2 pathway R-HSA-9755511
SARS-CoV-2 Infection R-HSA-9694516
VEGFA-VEGFR2 Pathway R-HSA-4420097
AKT-mediated inactivation of FOXO1A R-HSA-211163
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PDE3B signalling R-HSA-165160
Vesicle-mediated transport R-HSA-5653656
Cellular responses to stress R-HSA-2262752
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Degradation R-HSA-6804757
AKT phosphorylates targets in the nucleus R-HSA-198693
Cellular responses to stimuli R-HSA-8953897
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
SARS-CoV-2-host interactions R-HSA-9705683
Cellular response to chemical stress R-HSA-9711123
TP53 Regulates Metabolic Genes R-HSA-5628897
Rab regulation of trafficking R-HSA-9007101
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ERBB2 R-HSA-1227986
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Activation of BH3-only proteins R-HSA-114452
Intrinsic Pathway for Apoptosis R-HSA-109606
RUNX2 regulates genes involved in cell migration R-HSA-8941332
G-protein beta:gamma signalling R-HSA-397795
PI3K/AKT Signaling in Cancer R-HSA-2219528
Cytokine Signaling in Immune system R-HSA-1280215
FOXO-mediated transcription R-HSA-9614085
S Phase R-HSA-69242
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Membrane Trafficking R-HSA-199991
Regulation of beta-cell development R-HSA-186712
IGF1R signaling cascade R-HSA-2428924
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
RNA Polymerase II Transcription R-HSA-73857
IRS-related events triggered by IGF1R R-HSA-2428928
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX2 R-HSA-8878166
AKT phosphorylates targets in the cytosol R-HSA-198323
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Signaling by VEGF R-HSA-194138
Signaling by Insulin receptor R-HSA-74752
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Cell Cycle, Mitotic R-HSA-69278
Downregulation of ERBB2 signaling R-HSA-8863795
PI3K Cascade R-HSA-109704
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
FLT3 Signaling R-HSA-9607240
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Regulation of TP53 Activity R-HSA-5633007
PKB-mediated events R-HSA-109703
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Costimulation by the CD28 family R-HSA-388841
Insulin receptor signalling cascade R-HSA-74751
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
CD28 co-stimulation R-HSA-389356
Regulation of TP53 Activity through Acetylation R-HSA-6804758
CTLA4 inhibitory signaling R-HSA-389513
CD28 dependent PI3K/Akt signaling R-HSA-389357
ESR-mediated signaling R-HSA-8939211
Inhibition of TSC complex formation by PKB R-HSA-165181
Gene expression (Transcription) R-HSA-74160
Signaling by GPCR R-HSA-372790
SARS-CoV Infections R-HSA-9679506
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
SARS-CoV-2 Infection R-HSA-9694516
Cellular responses to stress R-HSA-2262752
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
SARS-CoV-2-host interactions R-HSA-9705683
CTLA4 inhibitory signaling R-HSA-389513
Developmental Biology R-HSA-1266738
GPCR downstream signalling R-HSA-388396
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Gene expression (Transcription) R-HSA-74160
TP53 Regulates Metabolic Genes R-HSA-5628897
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
MTOR signalling R-HSA-165159
Mitotic G1 phase and G1/S transition R-HSA-453279
IRS-related events triggered by IGF1R R-HSA-2428928
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Activity R-HSA-5633007
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Inhibition of TSC complex formation by PKB R-HSA-165181
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of localization of FOXO transcription factors R-HSA-9614399
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Membrane Trafficking R-HSA-199991
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
PDE3B signalling R-HSA-165160
Costimulation by the CD28 family R-HSA-388841
Regulation of gene expression in beta cells R-HSA-210745
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Nuclear Receptors R-HSA-9006931
Apoptosis R-HSA-109581
AKT-mediated inactivation of FOXO1A R-HSA-211163
Programmed Cell Death R-HSA-5357801
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by ERBB2 R-HSA-1227986
Generic Transcription Pathway R-HSA-212436
Signaling by GPCR R-HSA-372790
Cellular response to chemical stress R-HSA-9711123
Regulation of beta-cell development R-HSA-186712
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PKB-mediated events R-HSA-109703
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
CD28 co-stimulation R-HSA-389356
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of TP53 Degradation R-HSA-6804757
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
IRS-mediated signalling R-HSA-112399
Disease R-HSA-1643685
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Acetylation R-HSA-6804758
G-protein beta:gamma signalling R-HSA-397795
Downregulation of ERBB2 signaling R-HSA-8863795
S Phase R-HSA-69242
Extra-nuclear estrogen signaling R-HSA-9009391
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Cell Cycle R-HSA-1640170
IGF1R signaling cascade R-HSA-2428924
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of TP53 Expression and Degradation R-HSA-6806003
SARS-CoV Infections R-HSA-9679506
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Activation of BAD and translocation to mitochondria R-HSA-111447
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
CD28 dependent PI3K/Akt signaling R-HSA-389357
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Rab regulation of trafficking R-HSA-9007101
FLT3 Signaling R-HSA-9607240
PI3K/AKT Signaling in Cancer R-HSA-2219528
FOXO-mediated transcription R-HSA-9614085
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
AKT phosphorylates targets in the nucleus R-HSA-198693
Signaling by Insulin receptor R-HSA-74752
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
Vesicle-mediated transport R-HSA-5653656
PIP3 activates AKT signaling R-HSA-1257604
AKT phosphorylates targets in the cytosol R-HSA-198323
Activation of AKT2 R-HSA-165158
Cell Cycle, Mitotic R-HSA-69278
PI3K Cascade R-HSA-109704
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Regulation of localization of FOXO transcription factors R-HSA-9614399
TCF dependent signaling in response to WNT R-HSA-201681
AKT phosphorylates targets in the cytosol R-HSA-198323
ESR-mediated signaling R-HSA-8939211
Downregulation of ERBB2 signaling R-HSA-8863795
CD28 co-stimulation R-HSA-389356
MTOR signalling R-HSA-165159
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by ERBB2 R-HSA-1227986
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of beta-cell development R-HSA-186712
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
S Phase R-HSA-69242
Programmed Cell Death R-HSA-5357801
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Metabolic Genes R-HSA-5628897
Gene expression (Transcription) R-HSA-74160
Cell Cycle R-HSA-1640170
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Extra-nuclear estrogen signaling R-HSA-9009391
AKT phosphorylates targets in the nucleus R-HSA-198693
IRS-related events triggered by IGF1R R-HSA-2428928
Insulin receptor signalling cascade R-HSA-74751
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Developmental Biology R-HSA-1266738
Signaling by Nuclear Receptors R-HSA-9006931
G beta:gamma signalling through PI3Kgamma R-HSA-392451
SARS-CoV-2 Infection R-HSA-9694516
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AKT-mediated inactivation of FOXO1A R-HSA-211163
Cyclin E associated events during G1/S transition R-HSA-69202
CD28 dependent PI3K/Akt signaling R-HSA-389357
FOXO-mediated transcription R-HSA-9614085
Generic Transcription Pathway R-HSA-212436
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Membrane Trafficking R-HSA-199991
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates genes involved in cell migration R-HSA-8941332
PI3K/AKT Signaling in Cancer R-HSA-2219528
IRS-mediated signalling R-HSA-112399
Costimulation by the CD28 family R-HSA-388841
Rab regulation of trafficking R-HSA-9007101
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
VEGFR2 mediated vascular permeability R-HSA-5218920
CTLA4 inhibitory signaling R-HSA-389513
Regulation of gene expression in beta cells R-HSA-210745
Signaling by VEGF R-HSA-194138
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
IGF1R signaling cascade R-HSA-2428924
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Negative regulation of the PI3K/AKT network R-HSA-199418
VEGFA-VEGFR2 Pathway R-HSA-4420097
GPCR downstream signalling R-HSA-388396
FLT3 Signaling R-HSA-9607240
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Activation of BAD and translocation to mitochondria R-HSA-111447
Apoptosis R-HSA-109581
Regulation of TP53 Degradation R-HSA-6804757
Signaling by GPCR R-HSA-372790
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV Infections R-HSA-9679506
Activation of AKT2 R-HSA-165158
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
G1/S Transition R-HSA-69206
Intrinsic Pathway for Apoptosis R-HSA-109606
PI3K Cascade R-HSA-109704
Activation of BH3-only proteins R-HSA-114452
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
Cellular responses to stress R-HSA-2262752
PDE3B signalling R-HSA-165160
PKB-mediated events R-HSA-109703
Mitotic G1 phase and G1/S transition R-HSA-453279
Inhibition of TSC complex formation by PKB R-HSA-165181
Vesicle-mediated transport R-HSA-5653656
Regulation of TP53 Activity R-HSA-5633007
Signaling by WNT R-HSA-195721
G-protein beta:gamma signalling R-HSA-397795
KEAP1-NFE2L2 pathway R-HSA-9755511
SARS-CoV-2-host interactions R-HSA-9705683
Immune System R-HSA-168256
Activation of BH3-only proteins R-HSA-114452
VEGFR2 mediated vascular permeability R-HSA-5218920
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148
IRS-mediated signalling R-HSA-112399
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV Infections R-HSA-9679506
Apoptosis R-HSA-109581
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of BAD and translocation to mitochondria R-HSA-111447
Costimulation by the CD28 family R-HSA-388841
Vesicle-mediated transport R-HSA-5653656
Regulation of TP53 Expression and Degradation R-HSA-6806003
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803
Activation of AKT2 R-HSA-165158
G-protein beta:gamma signalling R-HSA-397795
Membrane Trafficking R-HSA-199991
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Insulin receptor R-HSA-74752
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Developmental Biology R-HSA-1266738
TCF dependent signaling in response to WNT R-HSA-201681
TP53 Regulates Metabolic Genes R-HSA-5628897
IRS-related events triggered by IGF1R R-HSA-2428928
AKT phosphorylates targets in the cytosol R-HSA-198323
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
PI3K Cascade R-HSA-109704
Signaling by WNT R-HSA-195721
Regulation of PTEN stability and activity R-HSA-8948751
Programmed Cell Death R-HSA-5357801
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
CD28 co-stimulation R-HSA-389356
IGF1R signaling cascade R-HSA-2428924
S Phase R-HSA-69242
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Infectious disease R-HSA-5663205
MTOR signalling R-HSA-165159
CD28 dependent PI3K/Akt signaling R-HSA-389357
FLT3 Signaling R-HSA-9607240
AKT-mediated inactivation of FOXO1A R-HSA-211163
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
Inhibition of TSC complex formation by PKB R-HSA-165181
ESR-mediated signaling R-HSA-8939211
GPCR downstream signalling R-HSA-388396
Transcriptional regulation by RUNX2 R-HSA-8878166
SARS-CoV-2-host interactions R-HSA-9705683
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Rab regulation of trafficking R-HSA-9007101
Signaling by ERBB2 R-HSA-1227986
Intrinsic Pathway for Apoptosis R-HSA-109606
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Regulation of beta-cell development R-HSA-186712
Deactivation of the beta-catenin transactivating complex R-HSA-3769402
Signaling by GPCR R-HSA-372790
Intracellular signaling by second messengers R-HSA-9006925
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
RUNX2 regulates genes involved in cell migration R-HSA-8941332
Regulation of gene expression in beta cells R-HSA-210745
Regulation of localization of FOXO transcription factors R-HSA-9614399
Regulation of TP53 Degradation R-HSA-6804757
PIP3 activates AKT signaling R-HSA-1257604
AKT phosphorylates targets in the nucleus R-HSA-198693
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
CTLA4 inhibitory signaling R-HSA-389513
Negative regulation of the PI3K/AKT network R-HSA-199418
Adaptive Immune System R-HSA-1280218
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
FOXO-mediated transcription R-HSA-9614085
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Extra-nuclear estrogen signaling R-HSA-9009391
G1/S Transition R-HSA-69206
Regulation of TP53 Activity R-HSA-5633007
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-2 Infection R-HSA-9694516
Insulin receptor signalling cascade R-HSA-74751
Signaling by VEGF R-HSA-194138
Downregulation of ERBB2 signaling R-HSA-8863795
PDE3B signalling R-HSA-165160
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PKB-mediated events R-HSA-109703

Expression Atlas ENSG00000105221
LRG display in Ensembl gene LRG_1391
NCBI gene (formerly Entrezgene) 208
GeneCards 392
HGNC Symbol HGNC:392
MIM gene 164731
MIM morbid 240900
UniProtKB Gene Name P31751
WikiGene 208
Gene: AURKC
Ensembl ID : ENSG00000105146
Description: aurora kinase C
Gene Synonyms: ARK3,AURC,STK13
1 APIs:
99 Possible Orthologues:

Expression Atlas ENSG00000105146
NCBI gene (formerly Entrezgene) 6795
GeneCards 11391
HGNC Symbol HGNC:11391
MIM gene 603495
MIM morbid 243060
UniProtKB Gene Name Q9UQB9
WikiGene 6795
Gene: ACVRL1
Ensembl ID : ENSG00000139567
Description: activin A receptor like type 1
Gene Synonyms: ACVRLK1,ALK1,HHT,HHT2,ORW2
2 APIs:
358 Possible Orthologues:

Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signaling by TGFB family members R-HSA-9006936
Signaling by BMP R-HSA-201451
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000139567
LRG display in Ensembl gene LRG_543
NCBI gene (formerly Entrezgene) 94
GeneCards 175
HGNC Symbol HGNC:175
MIM gene 601284
MIM morbid 600376
UniProtKB Gene Name P37023
WikiGene 94