Gene: ATP1A1
Ensembl ID : ENSG00000163399
Description: ATPase Na+/K+ transporting subunit alpha 1
Gene Synonyms:
6 APIs:
328 Possible Orthologues:

Cardiac conduction R-HSA-5576891
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
SARS-CoV Infections R-HSA-9679506
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Ion transport by P-type ATPases R-HSA-936837
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
Cardiac conduction R-HSA-5576891
Ion channel transport R-HSA-983712
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Ion homeostasis R-HSA-5578775
Transport of small molecules R-HSA-382551
Cardiac conduction R-HSA-5576891
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Ion transport by P-type ATPases R-HSA-936837
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Ion channel transport R-HSA-983712
Muscle contraction R-HSA-397014
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Potential therapeutics for SARS R-HSA-9679191
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Ion channel transport R-HSA-983712
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837

Expression Atlas ENSG00000163399
NCBI gene (formerly Entrezgene) 476
GeneCards 799
HGNC Symbol HGNC:799
MIM gene 182310
MIM morbid 618314
UniProtKB Gene Name Q5TC05
WikiGene 476
Gene: SI
Ensembl ID : ENSG00000090402
Description: sucrase-isomaltase
Gene Synonyms:
2 APIs:
201 Possible Orthologues:

Digestion and absorption R-HSA-8963743
Digestion of dietary carbohydrate R-HSA-189085
Digestion R-HSA-8935690
Diseases of metabolism R-HSA-5668914
Diseases of carbohydrate metabolism R-HSA-5663084
Disease R-HSA-1643685
Intestinal saccharidase deficiencies R-HSA-5659898
Digestion and absorption R-HSA-8963743
Intestinal saccharidase deficiencies R-HSA-5659898
Disease R-HSA-1643685
Diseases of carbohydrate metabolism R-HSA-5663084
Diseases of metabolism R-HSA-5668914
Digestion of dietary carbohydrate R-HSA-189085
Digestion R-HSA-8935690
Digestion of dietary carbohydrate R-HSA-189085
Disease R-HSA-1643685
Diseases of carbohydrate metabolism R-HSA-5663084
Digestion R-HSA-8935690
Intestinal saccharidase deficiencies R-HSA-5659898
Digestion and absorption R-HSA-8963743
Diseases of metabolism R-HSA-5668914
Digestion and absorption R-HSA-8963743
Intestinal saccharidase deficiencies R-HSA-5659898
Digestion R-HSA-8935690
Diseases of carbohydrate metabolism R-HSA-5663084
Diseases of metabolism R-HSA-5668914
Digestion of dietary carbohydrate R-HSA-189085
Disease R-HSA-1643685
Intestinal saccharidase deficiencies R-HSA-5659898
Disease R-HSA-1643685
Digestion and absorption R-HSA-8963743
Diseases of carbohydrate metabolism R-HSA-5663084
Diseases of metabolism R-HSA-5668914
Digestion of dietary carbohydrate R-HSA-189085
Digestion R-HSA-8935690
Digestion of dietary carbohydrate R-HSA-189085
Digestion R-HSA-8935690
Intestinal saccharidase deficiencies R-HSA-5659898
Diseases of carbohydrate metabolism R-HSA-5663084
Disease R-HSA-1643685
Digestion and absorption R-HSA-8963743
Diseases of metabolism R-HSA-5668914
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Digestion R-HSA-8935690
Digestion of dietary carbohydrate R-HSA-189085
Digestion and absorption R-HSA-8963743
Diseases of carbohydrate metabolism R-HSA-5663084
Intestinal saccharidase deficiencies R-HSA-5659898

Expression Atlas ENSG00000090402
NCBI gene (formerly Entrezgene) 6476
GeneCards 10856
HGNC Symbol HGNC:10856
MIM gene 609845
MIM morbid 222900
UniProtKB Gene Name P14410
WikiGene 6476
Gene: PLA2G7
Ensembl ID : ENSG00000146070
Description: phospholipase A2 group VII
Gene Synonyms: LDL-PLA2,PAFAH
2 APIs:
206 Possible Orthologues:

Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Peptide hormone metabolism R-HSA-2980736
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Peptide hormone metabolism R-HSA-2980736
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Metabolism of proteins R-HSA-392499
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736

Expression Atlas ENSG00000146070
NCBI gene (formerly Entrezgene) 7941
GeneCards 9040
HGNC Symbol HGNC:9040
MIM gene 601690
MIM morbid 614278
UniProtKB Gene Name Q13093
WikiGene 7941
Gene: MGAM
Ensembl ID : ENSG00000257335
Description: maltase-glucoamylase
Gene Synonyms: MGA
4 APIs:
312 Possible Orthologues:

Digestion R-HSA-8935690
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Digestion and absorption R-HSA-8963743
Digestion R-HSA-8935690
Digestion of dietary carbohydrate R-HSA-189085
Digestion and absorption R-HSA-8963743
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Digestion of dietary carbohydrate R-HSA-189085
Digestion R-HSA-8935690
Immune System R-HSA-168256
Digestion and absorption R-HSA-8963743
Digestion R-HSA-8935690
Innate Immune System R-HSA-168249
Digestion of dietary carbohydrate R-HSA-189085
Neutrophil degranulation R-HSA-6798695
Neutrophil degranulation R-HSA-6798695
Digestion of dietary carbohydrate R-HSA-189085
Digestion R-HSA-8935690
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Digestion and absorption R-HSA-8963743
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Digestion and absorption R-HSA-8963743
Digestion of dietary carbohydrate R-HSA-189085
Immune System R-HSA-168256
Immune System R-HSA-168256
Digestion and absorption R-HSA-8963743
Digestion of dietary carbohydrate R-HSA-189085
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Digestion R-HSA-8935690
Digestion of dietary carbohydrate R-HSA-189085
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Digestion R-HSA-8935690
Digestion and absorption R-HSA-8963743
Innate Immune System R-HSA-168249

Expression Atlas ENSG00000257335
NCBI gene (formerly Entrezgene) 8972
GeneCards 7043
HGNC Symbol HGNC:7043
MIM gene 154360
UniProtKB Gene Name O43451
WikiGene 8972
Gene: MALT1
Ensembl ID : ENSG00000172175
Description: MALT1 paracaspase
Gene Synonyms: MLT,PCASP1
1 APIs:
197 Possible Orthologues:

Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Immune System R-HSA-168256
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
CLEC7A/inflammasome pathway R-HSA-5660668
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A/inflammasome pathway R-HSA-5660668
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A/inflammasome pathway R-HSA-5660668
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TCR signaling R-HSA-202403
CLEC7A/inflammasome pathway R-HSA-5660668
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of NF-kappaB in B cells R-HSA-1169091
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream TCR signaling R-HSA-202424

Expression Atlas ENSG00000172175
LRG display in Ensembl gene LRG_1221
NCBI gene (formerly Entrezgene) 10892
GeneCards 6819
HGNC Symbol HGNC:6819
MIM gene 604860
MIM morbid 615468
UniProtKB Gene Name Q9UDY8
WikiGene 10892
Gene: TOP1
Ensembl ID : ENSG00000198900
Description: DNA topoisomerase I
Gene Synonyms:
17 APIs:
273 Possible Orthologues:

Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation of DNA replication proteins R-HSA-4615885
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
SUMOylation of DNA replication proteins R-HSA-4615885
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation of DNA replication proteins R-HSA-4615885
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
SUMOylation of DNA replication proteins R-HSA-4615885

Expression Atlas ENSG00000198900
NCBI gene (formerly Entrezgene) 7150
GeneCards 11986
HGNC Symbol HGNC:11986
MIM gene 126420
UniProtKB Gene Name P11387
WikiGene 7150
Gene: FKBP1A
Ensembl ID : ENSG00000088832
Description: FKBP prolyl isomerase 1A
Gene Synonyms: FKBP-12,FKBP1,FKBP12,FKBP12C,PKC12,PPIASE
7 APIs:
159 Possible Orthologues:

Calcineurin activates NFAT R-HSA-2025928
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
SARS-CoV-1 Infection R-HSA-9678108
mTORC1-mediated signalling R-HSA-166208
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MTOR signalling R-HSA-165159
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1-host interactions R-HSA-9692914
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Disease R-HSA-1643685
MTOR signalling R-HSA-165159
Adaptive Immune System R-HSA-1280218
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Immune System R-HSA-168256
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Infectious disease R-HSA-5663205
mTORC1-mediated signalling R-HSA-166208
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
Calcineurin activates NFAT R-HSA-2025928
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV Infections R-HSA-9679506
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
MTOR signalling R-HSA-165159
mTORC1-mediated signalling R-HSA-166208
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Calcineurin activates NFAT R-HSA-2025928
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
SARS-CoV-1-host interactions R-HSA-9692914
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by TGFB family members R-HSA-9006936
Immune System R-HSA-168256
SARS-CoV Infections R-HSA-9679506
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Signaling by TGFB family members R-HSA-9006936
mTORC1-mediated signalling R-HSA-166208
SARS-CoV Infections R-HSA-9679506
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-1 Infection R-HSA-9678108
TGF-beta receptor signaling activates SMADs R-HSA-2173789
MTOR signalling R-HSA-165159
Signaling by TGF-beta Receptor Complex R-HSA-170834
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
SARS-CoV-1-host interactions R-HSA-9692914
Signal Transduction R-HSA-162582
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Immune System R-HSA-168256
SARS-CoV Infections R-HSA-9679506
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Calcineurin activates NFAT R-HSA-2025928
Infectious disease R-HSA-5663205
mTORC1-mediated signalling R-HSA-166208
Disease R-HSA-1643685
Signaling by TGF-beta Receptor Complex R-HSA-170834
MTOR signalling R-HSA-165159
Signaling by TGFB family members R-HSA-9006936
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1-host interactions R-HSA-9692914
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
MTOR signalling R-HSA-165159
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Calcineurin activates NFAT R-HSA-2025928
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Signal Transduction R-HSA-162582
mTORC1-mediated signalling R-HSA-166208
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
Potential therapeutics for SARS R-HSA-9679191
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling activates SMADs R-HSA-2173789
MTOR signalling R-HSA-165159
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Calcineurin activates NFAT R-HSA-2025928
Immune System R-HSA-168256
Signaling by TGFB family members R-HSA-9006936
SARS-CoV-1 Infection R-HSA-9678108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV-1-host interactions R-HSA-9692914
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Signal Transduction R-HSA-162582
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
SARS-CoV Infections R-HSA-9679506
mTORC1-mediated signalling R-HSA-166208
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
mTORC1-mediated signalling R-HSA-166208
SARS-CoV Infections R-HSA-9679506
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TGF-beta receptor signaling activates SMADs R-HSA-2173789
SARS-CoV-1-host interactions R-HSA-9692914
Potential therapeutics for SARS R-HSA-9679191
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351
Signaling by TGF-beta Receptor Complex R-HSA-170834
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Calcineurin activates NFAT R-HSA-2025928
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by TGFB family members R-HSA-9006936
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
SARS-CoV-1 Infection R-HSA-9678108
MTOR signalling R-HSA-165159
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791
Signaling by TGF-beta Receptor Complex R-HSA-170834
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Signaling by TGFB family members R-HSA-9006936
SARS-CoV Infections R-HSA-9679506
TGFBR1 LBD Mutants in Cancer R-HSA-3656535
Adaptive Immune System R-HSA-1280218
Potential therapeutics for SARS R-HSA-9679191
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
MTOR signalling R-HSA-165159
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TGF-beta receptor signaling activates SMADs R-HSA-2173789
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Calcineurin activates NFAT R-HSA-2025928
mTORC1-mediated signalling R-HSA-166208
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Loss of Function of TGFBR1 in Cancer R-HSA-3656534
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351

Expression Atlas ENSG00000088832
NCBI gene (formerly Entrezgene) 2280
GeneCards 3711
HGNC Symbol HGNC:3711
MIM gene 186945
UniProtKB Gene Name Q5W0X3
WikiGene 2280
Gene: TOP2A
Ensembl ID : ENSG00000131747
Description: DNA topoisomerase II alpha
Gene Synonyms: TOP2,TOP2ALPHA,TOPIIA
21 APIs:
206 Possible Orthologues:

Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
G0 and Early G1 R-HSA-1538133
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
SUMOylation of DNA replication proteins R-HSA-4615885
SUMOylation of DNA replication proteins R-HSA-4615885
Cell Cycle R-HSA-1640170
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Mitotic G1 phase and G1/S transition R-HSA-453279
G0 and Early G1 R-HSA-1538133
Cell Cycle, Mitotic R-HSA-69278
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation of DNA replication proteins R-HSA-4615885
SUMOylation R-HSA-2990846
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of proteins R-HSA-392499
Cell Cycle, Mitotic R-HSA-69278
G0 and Early G1 R-HSA-1538133
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
Cell Cycle R-HSA-1640170
SUMOylation R-HSA-2990846
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
SUMOylation of DNA replication proteins R-HSA-4615885
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
G0 and Early G1 R-HSA-1538133
Metabolism of proteins R-HSA-392499
G0 and Early G1 R-HSA-1538133
Metabolism of proteins R-HSA-392499
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
Mitotic G1 phase and G1/S transition R-HSA-453279
SUMOylation R-HSA-2990846
SUMOylation of DNA replication proteins R-HSA-4615885
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
Cell Cycle R-HSA-1640170
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
G0 and Early G1 R-HSA-1538133
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Cell Cycle R-HSA-1640170
G0 and Early G1 R-HSA-1538133
Cell Cycle, Mitotic R-HSA-69278
SUMOylation of DNA replication proteins R-HSA-4615885
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
SUMOylation of DNA replication proteins R-HSA-4615885
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cell Cycle, Mitotic R-HSA-69278
SUMOylation R-HSA-2990846
G0 and Early G1 R-HSA-1538133
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
SUMOylation of DNA replication proteins R-HSA-4615885
SUMOylation R-HSA-2990846
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
G0 and Early G1 R-HSA-1538133
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
SUMOylation of DNA replication proteins R-HSA-4615885
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cell Cycle, Mitotic R-HSA-69278
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277
G0 and Early G1 R-HSA-1538133
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846

Expression Atlas ENSG00000131747
NCBI gene (formerly Entrezgene) 7153
GeneCards 11989
HGNC Symbol HGNC:11989
MIM gene 126430
UniProtKB Gene Name P11388
WikiGene 7153