Gene: CXCR2
Ensembl ID : ENSG00000180871
Description: C-X-C motif chemokine receptor 2
Gene Synonyms: CD182,CMKAR2,IL8RB
6 APIs:
238 Possible Orthologues:

Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Immune System R-HSA-168256
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Chemokine receptors bind chemokines R-HSA-380108
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Neutrophil degranulation R-HSA-6798695
GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
G alpha (i) signalling events R-HSA-418594
Chemokine receptors bind chemokines R-HSA-380108
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Neutrophil degranulation R-HSA-6798695
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Immune System R-HSA-168256
Chemokine receptors bind chemokines R-HSA-380108
Innate Immune System R-HSA-168249
Innate Immune System R-HSA-168249
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Chemokine receptors bind chemokines R-HSA-380108
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Neutrophil degranulation R-HSA-6798695
Chemokine receptors bind chemokines R-HSA-380108
G alpha (i) signalling events R-HSA-418594
Chemokine receptors bind chemokines R-HSA-380108
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Immune System R-HSA-168256
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Chemokine receptors bind chemokines R-HSA-380108
GPCR downstream signalling R-HSA-388396
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Innate Immune System R-HSA-168249
Chemokine receptors bind chemokines R-HSA-380108
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Innate Immune System R-HSA-168249
Chemokine receptors bind chemokines R-HSA-380108
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
G alpha (i) signalling events R-HSA-418594
Immune System R-HSA-168256
G alpha (i) signalling events R-HSA-418594
Chemokine receptors bind chemokines R-HSA-380108
Innate Immune System R-HSA-168249
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Neutrophil degranulation R-HSA-6798695
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276

Expression Atlas ENSG00000180871
NCBI gene (formerly Entrezgene) 3579
GeneCards 6027
HGNC Symbol HGNC:6027
MIM gene 146928
MIM morbid 619407
UniProtKB Gene Name Q53PC4
WikiGene 3579
Gene: HTR3A
Ensembl ID : ENSG00000166736
Description: 5-hydroxytryptamine receptor 3A
Gene Synonyms: 5-HT3A,5-HT3R,HTR3
19 APIs:
207 Possible Orthologues:

Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Neuronal System R-HSA-112316
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315

Expression Atlas ENSG00000166736
NCBI gene (formerly Entrezgene) 3359
GeneCards 5297
HGNC Symbol HGNC:5297
MIM gene 182139
UniProtKB Gene Name P46098
WikiGene 3359
Gene: ADRA2C
Ensembl ID : ENSG00000184160
Description: adrenoceptor alpha 2C
Gene Synonyms: ADRA2L2,ADRA2RL2,ADRARL2
30 APIs:
227 Possible Orthologues:

G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (z) signalling events R-HSA-418597
Integration of energy metabolism R-HSA-163685
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Amine ligand-binding receptors R-HSA-375280
Regulation of insulin secretion R-HSA-422356
GPCR ligand binding R-HSA-500792
Metabolism R-HSA-1430728
Hemostasis R-HSA-109582
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Adrenoceptors R-HSA-390696
Platelet activation, signaling and aggregation R-HSA-76002
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Signaling by GPCR R-HSA-372790
Metabolism of proteins R-HSA-392499
Surfactant metabolism R-HSA-5683826
Platelet Aggregation (Plug Formation) R-HSA-76009
Hemostasis R-HSA-109582
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Adrenoceptors R-HSA-390696
Regulation of insulin secretion R-HSA-422356
Amine ligand-binding receptors R-HSA-375280
Platelet Aggregation (Plug Formation) R-HSA-76009
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Metabolism R-HSA-1430728
Surfactant metabolism R-HSA-5683826
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (z) signalling events R-HSA-418597
G alpha (i) signalling events R-HSA-418594
Platelet activation, signaling and aggregation R-HSA-76002
Integration of energy metabolism R-HSA-163685
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Metabolism of proteins R-HSA-392499
G alpha (i) signalling events R-HSA-418594
Metabolism R-HSA-1430728
Regulation of insulin secretion R-HSA-422356
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Surfactant metabolism R-HSA-5683826
Platelet Aggregation (Plug Formation) R-HSA-76009
GPCR ligand binding R-HSA-500792
Amine ligand-binding receptors R-HSA-375280
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
Platelet activation, signaling and aggregation R-HSA-76002
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Metabolism of proteins R-HSA-392499
Integration of energy metabolism R-HSA-163685
Adrenoceptors R-HSA-390696
Integration of energy metabolism R-HSA-163685
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Regulation of insulin secretion R-HSA-422356
Adrenoceptors R-HSA-390696
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Platelet Aggregation (Plug Formation) R-HSA-76009
Surfactant metabolism R-HSA-5683826
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Amine ligand-binding receptors R-HSA-375280
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
G alpha (z) signalling events R-HSA-418597
GPCR ligand binding R-HSA-500792
Metabolism R-HSA-1430728
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Regulation of insulin secretion R-HSA-422356
G alpha (z) signalling events R-HSA-418597
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Metabolism of proteins R-HSA-392499
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Adrenoceptors R-HSA-390696
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Integration of energy metabolism R-HSA-163685
Platelet Aggregation (Plug Formation) R-HSA-76009
Amine ligand-binding receptors R-HSA-375280
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism R-HSA-1430728
Surfactant metabolism R-HSA-5683826
G alpha (z) signalling events R-HSA-418597
Amine ligand-binding receptors R-HSA-375280
Platelet Aggregation (Plug Formation) R-HSA-76009
Platelet activation, signaling and aggregation R-HSA-76002
Regulation of insulin secretion R-HSA-422356
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Integration of energy metabolism R-HSA-163685
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Adrenoceptors R-HSA-390696
Metabolism R-HSA-1430728
Surfactant metabolism R-HSA-5683826
Hemostasis R-HSA-109582
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Metabolism of proteins R-HSA-392499
Platelet Aggregation (Plug Formation) R-HSA-76009
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023
Regulation of insulin secretion R-HSA-422356
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Surfactant metabolism R-HSA-5683826
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042
Adrenoceptors R-HSA-390696
Signaling by GPCR R-HSA-372790
Platelet activation, signaling and aggregation R-HSA-76002
Integration of energy metabolism R-HSA-163685
Amine ligand-binding receptors R-HSA-375280
G alpha (z) signalling events R-HSA-418597
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000184160
NCBI gene (formerly Entrezgene) 152
GeneCards 283
HGNC Symbol HGNC:283
MIM gene 104250
MIM morbid 104250
UniProtKB Gene Name Q4W594
WikiGene 152
Gene: PTGFR
Ensembl ID : ENSG00000122420
Description: prostaglandin F receptor
Gene Synonyms: FP
8 APIs:
195 Possible Orthologues:

GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Prostanoid ligand receptors R-HSA-391908
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Eicosanoid ligand-binding receptors R-HSA-391903
Eicosanoid ligand-binding receptors R-HSA-391903
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Prostanoid ligand receptors R-HSA-391908
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Prostanoid ligand receptors R-HSA-391908
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Eicosanoid ligand-binding receptors R-HSA-391903
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Prostanoid ligand receptors R-HSA-391908
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Eicosanoid ligand-binding receptors R-HSA-391903
Prostanoid ligand receptors R-HSA-391908
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Eicosanoid ligand-binding receptors R-HSA-391903
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Prostanoid ligand receptors R-HSA-391908
Eicosanoid ligand-binding receptors R-HSA-391903
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Eicosanoid ligand-binding receptors R-HSA-391903
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Prostanoid ligand receptors R-HSA-391908
Eicosanoid ligand-binding receptors R-HSA-391903
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Prostanoid ligand receptors R-HSA-391908
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Eicosanoid ligand-binding receptors R-HSA-391903
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Prostanoid ligand receptors R-HSA-391908
Signal Transduction R-HSA-162582
Eicosanoid ligand-binding receptors R-HSA-391903
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Prostanoid ligand receptors R-HSA-391908
Prostanoid ligand receptors R-HSA-391908
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Eicosanoid ligand-binding receptors R-HSA-391903

Expression Atlas ENSG00000122420
NCBI gene (formerly Entrezgene) 5737
GeneCards 9600
HGNC Symbol HGNC:9600
MIM gene 600563
UniProtKB Gene Name P43088
WikiGene 5737
Gene: FFAR1
Ensembl ID : ENSG00000126266
Description: free fatty acid receptor 1
Gene Synonyms: FFA1R,GPR40
2 APIs:
76 Possible Orthologues:

GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Peptide hormone metabolism R-HSA-2980736
Free fatty acids regulate insulin secretion R-HSA-400451
Integration of energy metabolism R-HSA-163685
Regulation of insulin secretion R-HSA-422356
Metabolism of proteins R-HSA-392499
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511
Metabolism R-HSA-1430728
Free fatty acid receptors R-HSA-444209
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Incretin synthesis, secretion, and inactivation R-HSA-400508
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771
Free fatty acid receptors R-HSA-444209
Signaling by GPCR R-HSA-372790
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316
Incretin synthesis, secretion, and inactivation R-HSA-400508
Integration of energy metabolism R-HSA-163685
Peptide hormone metabolism R-HSA-2980736
GPCR ligand binding R-HSA-500792
Metabolism of proteins R-HSA-392499
Free fatty acids regulate insulin secretion R-HSA-400451
Regulation of insulin secretion R-HSA-422356
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316
Integration of energy metabolism R-HSA-163685
Free fatty acids regulate insulin secretion R-HSA-400451
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Free fatty acid receptors R-HSA-444209
Incretin synthesis, secretion, and inactivation R-HSA-400508
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Regulation of insulin secretion R-HSA-422356
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Incretin synthesis, secretion, and inactivation R-HSA-400508
Regulation of insulin secretion R-HSA-422356
Metabolism R-HSA-1430728
Integration of energy metabolism R-HSA-163685
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771
Free fatty acids regulate insulin secretion R-HSA-400451
Signaling by GPCR R-HSA-372790
Metabolism of proteins R-HSA-392499
Free fatty acid receptors R-HSA-444209
G alpha (q) signalling events R-HSA-416476
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511
GPCR downstream signalling R-HSA-388396
Peptide hormone metabolism R-HSA-2980736
Metabolism R-HSA-1430728
Regulation of insulin secretion R-HSA-422356
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511
Integration of energy metabolism R-HSA-163685
Incretin synthesis, secretion, and inactivation R-HSA-400508
Peptide hormone metabolism R-HSA-2980736
Free fatty acids regulate insulin secretion R-HSA-400451
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771
GPCR downstream signalling R-HSA-388396
Free fatty acid receptors R-HSA-444209
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316
Incretin synthesis, secretion, and inactivation R-HSA-400508
Signaling by GPCR R-HSA-372790
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511
Metabolism of proteins R-HSA-392499
Integration of energy metabolism R-HSA-163685
GPCR ligand binding R-HSA-500792
Free fatty acid receptors R-HSA-444209
G alpha (q) signalling events R-HSA-416476
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771
Free fatty acids regulate insulin secretion R-HSA-400451
Signal Transduction R-HSA-162582
Peptide hormone metabolism R-HSA-2980736
GPCR downstream signalling R-HSA-388396
Regulation of insulin secretion R-HSA-422356
Metabolism R-HSA-1430728
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Integration of energy metabolism R-HSA-163685
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771
Incretin synthesis, secretion, and inactivation R-HSA-400508
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316
Metabolism R-HSA-1430728
Peptide hormone metabolism R-HSA-2980736
GPCR ligand binding R-HSA-500792
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Free fatty acid receptors R-HSA-444209
Free fatty acids regulate insulin secretion R-HSA-400451
Regulation of insulin secretion R-HSA-422356
Metabolism of proteins R-HSA-392499

Expression Atlas ENSG00000126266
NCBI gene (formerly Entrezgene) 2864
GeneCards 4498
HGNC Symbol HGNC:4498
MIM gene 603820
UniProtKB Gene Name O14842
WikiGene 2864
Gene: PTAFR
Ensembl ID : ENSG00000169403
Description: platelet activating factor receptor
Gene Synonyms:
2 APIs:
224 Possible Orthologues:

Signaling by GPCR R-HSA-372790
Cytokine Signaling in Immune system R-HSA-1280215
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Interleukin-10 signaling R-HSA-6783783
Neutrophil degranulation R-HSA-6798695
Signal Transduction R-HSA-162582
Interferon Signaling R-HSA-913531
Immune System R-HSA-168256
Interferon gamma signaling R-HSA-877300
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signaling by Interleukins R-HSA-449147
Interferon gamma signaling R-HSA-877300
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
Interferon Signaling R-HSA-913531
Interleukin-10 signaling R-HSA-6783783
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Interferon gamma signaling R-HSA-877300
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Interleukin-10 signaling R-HSA-6783783
G alpha (q) signalling events R-HSA-416476
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
GPCR ligand binding R-HSA-500792
Interferon gamma signaling R-HSA-877300
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
GPCR downstream signalling R-HSA-388396
Signaling by Interleukins R-HSA-449147
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Interleukin-10 signaling R-HSA-6783783
Interferon Signaling R-HSA-913531
Signal Transduction R-HSA-162582
Interferon gamma signaling R-HSA-877300
Immune System R-HSA-168256
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Neutrophil degranulation R-HSA-6798695
Interleukin-10 signaling R-HSA-6783783
Signaling by GPCR R-HSA-372790
Cytokine Signaling in Immune system R-HSA-1280215
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
Signaling by Interleukins R-HSA-449147
G alpha (q) signalling events R-HSA-416476
Interleukin-10 signaling R-HSA-6783783
Interferon gamma signaling R-HSA-877300
Immune System R-HSA-168256
Interferon Signaling R-HSA-913531
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
GPCR ligand binding R-HSA-500792
Interleukin-10 signaling R-HSA-6783783
Interferon gamma signaling R-HSA-877300
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Interferon Signaling R-HSA-913531
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signaling by GPCR R-HSA-372790
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Interferon gamma signaling R-HSA-877300
Innate Immune System R-HSA-168249
Signaling by GPCR R-HSA-372790
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
Interferon Signaling R-HSA-913531
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Neutrophil degranulation R-HSA-6798695
GPCR downstream signalling R-HSA-388396
Interleukin-10 signaling R-HSA-6783783
Cytokine Signaling in Immune system R-HSA-1280215
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
Signaling by GPCR R-HSA-372790
Signaling by Interleukins R-HSA-449147
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Interferon Signaling R-HSA-913531
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
GPCR ligand binding R-HSA-500792
Interleukin-10 signaling R-HSA-6783783
G alpha (q) signalling events R-HSA-416476
Interferon gamma signaling R-HSA-877300
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
GPCR ligand binding R-HSA-500792
Immune System R-HSA-168256
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Neutrophil degranulation R-HSA-6798695
Signal Transduction R-HSA-162582
Interferon gamma signaling R-HSA-877300
Interferon Signaling R-HSA-913531
Signaling by GPCR R-HSA-372790
Interleukin-10 signaling R-HSA-6783783
G alpha (q) signalling events R-HSA-416476
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000169403
NCBI gene (formerly Entrezgene) 5724
GeneCards 9582
HGNC Symbol HGNC:9582
MIM gene 173393
UniProtKB Gene Name P25105
WikiGene 5724
Gene: ADORA2B
Ensembl ID : ENSG00000170425
Description: adenosine A2b receptor
Gene Synonyms:
5 APIs:
201 Possible Orthologues:

Surfactant metabolism R-HSA-5683826
Nucleotide-like (purinergic) receptors R-HSA-418038
Adenosine P1 receptors R-HSA-417973
Signal Transduction R-HSA-162582
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Infectious disease R-HSA-5663205
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Leishmania parasite growth and survival R-HSA-9664433
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Leishmania infection R-HSA-9658195
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Nucleotide-like (purinergic) receptors R-HSA-418038
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Leishmania parasite growth and survival R-HSA-9664433
Leishmania infection R-HSA-9658195
Adenosine P1 receptors R-HSA-417973
Infectious disease R-HSA-5663205
Surfactant metabolism R-HSA-5683826
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Adenosine P1 receptors R-HSA-417973
Infectious disease R-HSA-5663205
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Nucleotide-like (purinergic) receptors R-HSA-418038
Leishmania parasite growth and survival R-HSA-9664433
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Surfactant metabolism R-HSA-5683826
Metabolism of proteins R-HSA-392499
Adenosine P1 receptors R-HSA-417973
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Signaling by GPCR R-HSA-372790
Nucleotide-like (purinergic) receptors R-HSA-418038
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Leishmania parasite growth and survival R-HSA-9664433
G alpha (s) signalling events R-HSA-418555
Leishmania infection R-HSA-9658195
GPCR ligand binding R-HSA-500792
Surfactant metabolism R-HSA-5683826
Disease R-HSA-1643685
Disease R-HSA-1643685
Adenosine P1 receptors R-HSA-417973
Signaling by GPCR R-HSA-372790
Leishmania infection R-HSA-9658195
Leishmania parasite growth and survival R-HSA-9664433
G alpha (s) signalling events R-HSA-418555
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Surfactant metabolism R-HSA-5683826
Nucleotide-like (purinergic) receptors R-HSA-418038
Infectious disease R-HSA-5663205
Leishmania parasite growth and survival R-HSA-9664433
Metabolism of proteins R-HSA-392499
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
G alpha (s) signalling events R-HSA-418555
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Disease R-HSA-1643685
GPCR downstream signalling R-HSA-388396
Adenosine P1 receptors R-HSA-417973
Signaling by GPCR R-HSA-372790
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Surfactant metabolism R-HSA-5683826
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Nucleotide-like (purinergic) receptors R-HSA-418038
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Leishmania parasite growth and survival R-HSA-9664433
Surfactant metabolism R-HSA-5683826
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Infectious disease R-HSA-5663205
GPCR downstream signalling R-HSA-388396
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR ligand binding R-HSA-500792
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Metabolism of proteins R-HSA-392499
G alpha (s) signalling events R-HSA-418555
Adenosine P1 receptors R-HSA-417973
Infectious disease R-HSA-5663205
GPCR ligand binding R-HSA-500792
Metabolism of proteins R-HSA-392499
Leishmania infection R-HSA-9658195
G alpha (s) signalling events R-HSA-418555
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Leishmania parasite growth and survival R-HSA-9664433
Disease R-HSA-1643685
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Signaling by GPCR R-HSA-372790
Surfactant metabolism R-HSA-5683826
Nucleotide-like (purinergic) receptors R-HSA-418038
Adenosine P1 receptors R-HSA-417973
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signal Transduction R-HSA-162582
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Leishmania parasite growth and survival R-HSA-9664433
Metabolism of proteins R-HSA-392499
Leishmania infection R-HSA-9658195
Adenosine P1 receptors R-HSA-417973
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
G alpha (s) signalling events R-HSA-418555
Nucleotide-like (purinergic) receptors R-HSA-418038
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Surfactant metabolism R-HSA-5683826
GPCR downstream signalling R-HSA-388396
Metabolism of proteins R-HSA-392499
Signaling by GPCR R-HSA-372790
Adenosine P1 receptors R-HSA-417973
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Surfactant metabolism R-HSA-5683826
G alpha (s) signalling events R-HSA-418555
Infectious disease R-HSA-5663205
Leishmania parasite growth and survival R-HSA-9664433
Leishmania infection R-HSA-9658195
Nucleotide-like (purinergic) receptors R-HSA-418038
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Disease R-HSA-1643685
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851
GPCR ligand binding R-HSA-500792
Adenosine P1 receptors R-HSA-417973
Nucleotide-like (purinergic) receptors R-HSA-418038
Leishmania infection R-HSA-9658195
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Surfactant metabolism R-HSA-5683826
Metabolism of proteins R-HSA-392499
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821
Disease R-HSA-1643685
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Infectious disease R-HSA-5663205
Leishmania parasite growth and survival R-HSA-9664433
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851

Expression Atlas ENSG00000170425
NCBI gene (formerly Entrezgene) 136
GeneCards 264
HGNC Symbol HGNC:264
MIM gene 600446
UniProtKB Gene Name P29275
WikiGene 136
Gene: MTNR1B
Ensembl ID : ENSG00000134640
Description: melatonin receptor 1B
Gene Synonyms:
5 APIs:
107 Possible Orthologues:

Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076

Expression Atlas ENSG00000134640
NCBI gene (formerly Entrezgene) 4544
GeneCards 7464
HGNC Symbol HGNC:7464
MIM gene 600804
MIM morbid 125853
UniProtKB Gene Name P49286
WikiGene 4544