Gene: RET
Ensembl ID : ENSG00000165731
Description: ret proto-oncogene
Gene Synonyms: CDHF12,CDHR16,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET51
14 APIs:
205 Possible Orthologues:

Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Transcriptional Regulation by NPAS4 R-HSA-9634815
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
MAPK1/MAPK3 signaling R-HSA-5684996
RET signaling R-HSA-8853659
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by NPAS4 R-HSA-9634815
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
NPAS4 regulates expression of target genes R-HSA-9768919
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
RET signaling R-HSA-8853659
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
RET signaling R-HSA-8853659
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
RET signaling R-HSA-8853659
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
NPAS4 regulates expression of target genes R-HSA-9768919
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
Axon guidance R-HSA-422475
NPAS4 regulates expression of target genes R-HSA-9768919
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
RET signaling R-HSA-8853659
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Axon guidance R-HSA-422475
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
NPAS4 regulates expression of target genes R-HSA-9768919
RET signaling R-HSA-8853659
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional Regulation by NPAS4 R-HSA-9634815
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
NPAS4 regulates expression of target genes R-HSA-9768919
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
RET signaling R-HSA-8853659
Transcriptional Regulation by NPAS4 R-HSA-9634815
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
NPAS4 regulates expression of target genes R-HSA-9768919
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by NPAS4 R-HSA-9634815
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659

Expression Atlas ENSG00000165731
LRG display in Ensembl gene LRG_518
NCBI gene (formerly Entrezgene) 5979
GeneCards 9967
HGNC Symbol HGNC:9967
MIM gene 164761
MIM morbid 171400
UniProtKB Gene Name P07949
WikiGene 5979
Gene: PSMA1
Ensembl ID : ENSG00000129084
Description: proteasome 20S subunit alpha 1
Gene Synonyms: HC2,MGC14542,MGC14575,MGC14751,MGC1667,MGC21459,MGC22853,MGC23915,NU,PROS30
6 APIs:
237 Possible Orthologues:

TCF dependent signaling in response to WNT R-HSA-201681
S Phase R-HSA-69242
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Neddylation R-HSA-8951664
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
S Phase R-HSA-69242
TCR signaling R-HSA-202403
MAPK family signaling cascades R-HSA-5683057
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Deubiquitination R-HSA-5688426
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK6/MAPK4 signaling R-HSA-5687128
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing-Cross presentation R-HSA-1236975
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RAS by GAPs R-HSA-5658442
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
UCH proteinases R-HSA-5689603
Degradation of beta-catenin by the destruction complex R-HSA-195253
PTEN Regulation R-HSA-6807070
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Negative regulation of NOTCH4 signaling R-HSA-9604323
Infectious disease R-HSA-5663205
ABC-family proteins mediated transport R-HSA-382556
Signaling by ROBO receptors R-HSA-376176
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
Post-translational protein modification R-HSA-597592
Signaling by Hedgehog R-HSA-5358351
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK1/MAPK3 signaling R-HSA-5684996
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
Activation of NF-kappaB in B cells R-HSA-1169091
Synthesis of DNA R-HSA-69239
Hedgehog 'off' state R-HSA-5610787
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Vpu mediated degradation of CD4 R-HSA-180534
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
p53-Independent DNA Damage Response R-HSA-69610
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX3 expression and activity R-HSA-8941858
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of DVL R-HSA-4641258
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Nervous system development R-HSA-9675108
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Beta-catenin independent WNT signaling R-HSA-3858494
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication Pre-Initiation R-HSA-69002
Transport of small molecules R-HSA-382551
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cytokine Signaling in Immune system R-HSA-1280215
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Post-translational protein modification R-HSA-597592
Cell Cycle Checkpoints R-HSA-69620
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
UCH proteinases R-HSA-5689603
Signaling by WNT R-HSA-195721
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of RNA R-HSA-8953854
CLEC7A (Dectin-1) signaling R-HSA-5607764
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
DNA Replication R-HSA-69306
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Apoptosis R-HSA-109581
Host Interactions of HIV factors R-HSA-162909
ER-Phagosome pathway R-HSA-1236974
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
PCP/CE pathway R-HSA-4086400
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism R-HSA-1430728
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Asymmetric localization of PCP proteins R-HSA-4608870
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Assembly of the pre-replicative complex R-HSA-68867
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Checkpoints R-HSA-69481
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by Interleukins R-HSA-449147
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of GLI2 by the proteasome R-HSA-5610783
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
KEAP1-NFE2L2 pathway R-HSA-9755511
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Programmed Cell Death R-HSA-5357801
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
TCF dependent signaling in response to WNT R-HSA-201681
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK family signaling cascades R-HSA-5683057
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Switching of origins to a post-replicative state R-HSA-69052
C-type lectin receptors (CLRs) R-HSA-5621481
Developmental Biology R-HSA-1266738
ABC-family proteins mediated transport R-HSA-382556
Regulation of mitotic cell cycle R-HSA-453276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH4 R-HSA-9013694
UCH proteinases R-HSA-5689603
PCP/CE pathway R-HSA-4086400
Infectious disease R-HSA-5663205
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hh mutants are degraded by ERAD R-HSA-5362768
Downstream TCR signaling R-HSA-202424
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Checkpoints R-HSA-69481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transport of small molecules R-HSA-382551
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication R-HSA-69306
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'on' state R-HSA-5632684
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'off' state R-HSA-5610787
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle Checkpoints R-HSA-69620
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Asymmetric localization of PCP proteins R-HSA-4608870
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Deubiquitination R-HSA-5688426
Adaptive Immune System R-HSA-1280218
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Regulation of RAS by GAPs R-HSA-5658442
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
Hh mutants abrogate ligand secretion R-HSA-5387390
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Assembly of the pre-replicative complex R-HSA-68867
Generic Transcription Pathway R-HSA-212436
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
Metabolism of polyamines R-HSA-351202
G1/S DNA Damage Checkpoints R-HSA-69615
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI2 by the proteasome R-HSA-5610783
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Degradation of GLI1 by the proteasome R-HSA-5610780
HIV Infection R-HSA-162906
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
PCP/CE pathway R-HSA-4086400
Hedgehog 'off' state R-HSA-5610787
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of RNA R-HSA-8953854
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
Stabilization of p53 R-HSA-69541
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication R-HSA-69306
Programmed Cell Death R-HSA-5357801
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ROBO receptors R-HSA-376176
RAF/MAP kinase cascade R-HSA-5673001
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
UCH proteinases R-HSA-5689603
Signaling by NOTCH R-HSA-157118
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Apoptosis R-HSA-109581
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
Cellular response to chemical stress R-HSA-9711123
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Interleukin-1 signaling R-HSA-9020702
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
Orc1 removal from chromatin R-HSA-68949
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
HIV Infection R-HSA-162906
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH R-HSA-157118
Hedgehog 'off' state R-HSA-5610787
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
Asymmetric localization of PCP proteins R-HSA-4608870
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Generic Transcription Pathway R-HSA-212436
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
Host Interactions of HIV factors R-HSA-162909
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
FCERI mediated NF-kB activation R-HSA-2871837
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
RNA Polymerase II Transcription R-HSA-73857
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
M Phase R-HSA-68886
Degradation of DVL R-HSA-4641258
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism R-HSA-1430728
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Interleukins R-HSA-449147
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Switching of origins to a post-replicative state R-HSA-69052
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of RNA R-HSA-8953854
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin E associated events during G1/S transition R-HSA-69202
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to chemical stress R-HSA-9711123
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK1/MAPK3 signaling R-HSA-5684996
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
UCH proteinases R-HSA-5689603
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle R-HSA-1640170
ABC-family proteins mediated transport R-HSA-382556
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream TCR signaling R-HSA-202424
Signaling by Hedgehog R-HSA-5358351
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Separation of Sister Chromatids R-HSA-2467813
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing-Cross presentation R-HSA-1236975
G2/M Checkpoints R-HSA-69481
S Phase R-HSA-69242
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
G1/S Transition R-HSA-69206
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
Synthesis of DNA R-HSA-69239
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PCP/CE pathway R-HSA-4086400
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
KEAP1-NFE2L2 pathway R-HSA-9755511
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'off' state R-HSA-5610787
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S DNA Damage Checkpoints R-HSA-69615
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Regulation of mitotic cell cycle R-HSA-453276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of DVL R-HSA-4641258
ABC-family proteins mediated transport R-HSA-382556
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Intracellular signaling by second messengers R-HSA-9006925
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK family signaling cascades R-HSA-5683057
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
Nuclear events mediated by NFE2L2 R-HSA-9759194
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
S Phase R-HSA-69242
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by Interleukins R-HSA-449147
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Metaphase and Anaphase R-HSA-2555396
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Degradation of AXIN R-HSA-4641257
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX3 R-HSA-8878159
Stabilization of p53 R-HSA-69541
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Signaling by Hedgehog R-HSA-5358351
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
Transport of small molecules R-HSA-382551
Separation of Sister Chromatids R-HSA-2467813
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Downstream TCR signaling R-HSA-202424
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of Apoptosis R-HSA-169911
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX3 expression and activity R-HSA-8941858
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stimuli R-HSA-8953897
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Axon guidance R-HSA-422475
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of AXIN R-HSA-4641257
Intracellular signaling by second messengers R-HSA-9006925
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of DVL R-HSA-4641258
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
Ub-specific processing proteases R-HSA-5689880
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
PCP/CE pathway R-HSA-4086400
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog ligand biogenesis R-HSA-5358346
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Regulation of RAS by GAPs R-HSA-5658442
MAPK family signaling cascades R-HSA-5683057
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neddylation R-HSA-8951664
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Gene expression (Transcription) R-HSA-74160
Interleukin-1 signaling R-HSA-9020702
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Hedgehog 'on' state R-HSA-5632684
Mitotic Anaphase R-HSA-68882
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Hedgehog R-HSA-5358351
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TCR signaling R-HSA-202403
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
Programmed Cell Death R-HSA-5357801
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Synthesis of DNA R-HSA-69239
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Assembly of the pre-replicative complex R-HSA-68867
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-1 signaling R-HSA-9020702
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX2 R-HSA-8878166
RAF/MAP kinase cascade R-HSA-5673001
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
Cellular response to chemical stress R-HSA-9711123
Mitotic Anaphase R-HSA-68882
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC transporter disorders R-HSA-5619084
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle, Mitotic R-HSA-69278
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Infectious disease R-HSA-5663205
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
HIV Infection R-HSA-162906
Regulation of RAS by GAPs R-HSA-5658442
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Intracellular signaling by second messengers R-HSA-9006925
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX3 R-HSA-8878159
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle Checkpoints R-HSA-69620
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Ub-specific processing proteases R-HSA-5689880
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
M Phase R-HSA-68886
HIV Infection R-HSA-162906
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disorders of transmembrane transporters R-HSA-5619115
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Axon guidance R-HSA-422475
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Nervous system development R-HSA-9675108
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
Mitotic G2-G2/M phases R-HSA-453274
Host Interactions of HIV factors R-HSA-162909
Metabolism of amino acids and derivatives R-HSA-71291
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of RNA R-HSA-8953854
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
G2/M Checkpoints R-HSA-69481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic Anaphase R-HSA-68882
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to hypoxia R-HSA-1234174
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH R-HSA-157118
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 signaling R-HSA-9020702
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Cellular responses to stress R-HSA-2262752
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
Stabilization of p53 R-HSA-69541
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Post-translational protein modification R-HSA-597592
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cyclin E associated events during G1/S transition R-HSA-69202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH4 R-HSA-9013694
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
DNA Replication R-HSA-69306
Neddylation R-HSA-8951664
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Nuclear events mediated by NFE2L2 R-HSA-9759194
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Gene expression (Transcription) R-HSA-74160
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of GLI1 by the proteasome R-HSA-5610780
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Switching of origins to a post-replicative state R-HSA-69052
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
CLEC7A (Dectin-1) signaling R-HSA-5607764
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
Host Interactions of HIV factors R-HSA-162909
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
Regulation of PTEN stability and activity R-HSA-8948751
Vpu mediated degradation of CD4 R-HSA-180534
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
RNA Polymerase II Transcription R-HSA-73857
p53-Independent DNA Damage Response R-HSA-69610
Developmental Biology R-HSA-1266738
Cell Cycle, Mitotic R-HSA-69278
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication R-HSA-69306
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Assembly of the pre-replicative complex R-HSA-68867
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Immune System R-HSA-168256
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Anaphase R-HSA-68882
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
Signal Transduction R-HSA-162582
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI2 by the proteasome R-HSA-5610783
M Phase R-HSA-68886
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
C-type lectin receptors (CLRs) R-HSA-5621481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH4 R-HSA-9013694
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Axon guidance R-HSA-422475
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK family signaling cascades R-HSA-5683057
Stabilization of p53 R-HSA-69541
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
M Phase R-HSA-68886
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants are degraded by ERAD R-HSA-5362768
Host Interactions of HIV factors R-HSA-162909
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
G2/M Checkpoints R-HSA-69481
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
DNA Replication Pre-Initiation R-HSA-69002
Downstream TCR signaling R-HSA-202424
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Beta-catenin independent WNT signaling R-HSA-3858494
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
Regulation of PTEN stability and activity R-HSA-8948751
DNA Replication R-HSA-69306
Cellular responses to stimuli R-HSA-8953897
G1/S DNA Damage Checkpoints R-HSA-69615
ER-Phagosome pathway R-HSA-1236974
Signaling by Hedgehog R-HSA-5358351
Infectious disease R-HSA-5663205
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nervous system development R-HSA-9675108
Cell Cycle R-HSA-1640170
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Adaptive Immune System R-HSA-1280218
Neddylation R-HSA-8951664
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signal Transduction R-HSA-162582
Vpu mediated degradation of CD4 R-HSA-180534
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Degradation of GLI1 by the proteasome R-HSA-5610780
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 family signaling R-HSA-446652
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
Synthesis of DNA R-HSA-69239
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Gene expression (Transcription) R-HSA-74160
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ROBO receptors R-HSA-376176
Switching of origins to a post-replicative state R-HSA-69052
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI2 by the proteasome R-HSA-5610783
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PCP/CE pathway R-HSA-4086400
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
G2/M Transition R-HSA-69275
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Transport of small molecules R-HSA-382551
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
Developmental Biology R-HSA-1266738
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Mitotic G2-G2/M phases R-HSA-453274
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114

Expression Atlas ENSG00000129084
NCBI gene (formerly Entrezgene) 5682
GeneCards 9530
HGNC Symbol HGNC:9530
MIM gene 602854
UniProtKB Gene Name P25786
WikiGene 5682
Gene: PSMB2
Ensembl ID : ENSG00000126067
Description: proteasome 20S subunit beta 2
Gene Synonyms: HC7-I
6 APIs:
218 Possible Orthologues:

G1/S Transition R-HSA-69206
Signaling by NOTCH R-HSA-157118
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle Checkpoints R-HSA-69620
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of RNA R-HSA-8953854
MAPK1/MAPK3 signaling R-HSA-5684996
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Apoptosis R-HSA-109581
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Antigen processing-Cross presentation R-HSA-1236975
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of proteins R-HSA-392499
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RAS by GAPs R-HSA-5658442
TCR signaling R-HSA-202403
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G2-G2/M phases R-HSA-453274
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
Immune System R-HSA-168256
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Beta-catenin independent WNT signaling R-HSA-3858494
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
G1/S DNA Damage Checkpoints R-HSA-69615
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Anaphase R-HSA-68882
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
Antigen processing-Cross presentation R-HSA-1236975
UCH proteinases R-HSA-5689603
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
p53-Independent DNA Damage Response R-HSA-69610
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cytokine Signaling in Immune system R-HSA-1280215
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Deubiquitination R-HSA-5688426
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transport of small molecules R-HSA-382551
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
RAF/MAP kinase cascade R-HSA-5673001
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Immune System R-HSA-168256
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Cyclin E associated events during G1/S transition R-HSA-69202
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Checkpoints R-HSA-69481
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CLEC7A (Dectin-1) signaling R-HSA-5607764
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nervous system development R-HSA-9675108
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Synthesis of DNA R-HSA-69239
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX2 R-HSA-8878166
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Activation of NF-kappaB in B cells R-HSA-1169091
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Hedgehog 'off' state R-HSA-5610787
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Regulation of RAS by GAPs R-HSA-5658442
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 family signaling R-HSA-446652
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Vpu mediated degradation of CD4 R-HSA-180534
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Disorders of transmembrane transporters R-HSA-5619115
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
TCR signaling R-HSA-202403
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Beta-catenin independent WNT signaling R-HSA-3858494
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing-Cross presentation R-HSA-1236975
MAPK family signaling cascades R-HSA-5683057
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
ER-Phagosome pathway R-HSA-1236974
RNA Polymerase II Transcription R-HSA-73857
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by WNT R-HSA-195721
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PIP3 activates AKT signaling R-HSA-1257604
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Cytokine Signaling in Immune system R-HSA-1280215
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH4 R-HSA-9013694
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle Checkpoints R-HSA-69620
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin E associated events during G1/S transition R-HSA-69202
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
p53-Independent DNA Damage Response R-HSA-69610
Disease R-HSA-1643685
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Downstream TCR signaling R-HSA-202424
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Infectious disease R-HSA-5663205
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Axon guidance R-HSA-422475
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants are degraded by ERAD R-HSA-5362768
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Stabilization of p53 R-HSA-69541
Programmed Cell Death R-HSA-5357801
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Switching of origins to a post-replicative state R-HSA-69052
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Interleukin-1 signaling R-HSA-9020702
Degradation of DVL R-HSA-4641258
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Apoptosis R-HSA-109581
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S DNA Damage Checkpoints R-HSA-69615
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK1/MAPK3 signaling R-HSA-5684996
Class I MHC mediated antigen processing & presentation R-HSA-983169
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
Immune System R-HSA-168256
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Apoptosis R-HSA-109581
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of Apoptosis R-HSA-169911
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ER-Phagosome pathway R-HSA-1236974
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
HIV Infection R-HSA-162906
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Host Interactions of HIV factors R-HSA-162909
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'on' state R-HSA-5632684
Programmed Cell Death R-HSA-5357801
Cellular responses to stress R-HSA-2262752
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
DNA Replication R-HSA-69306
p53-Dependent G1 DNA Damage Response R-HSA-69563
Vpu mediated degradation of CD4 R-HSA-180534
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
MAPK1/MAPK3 signaling R-HSA-5684996
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
Signaling by Hedgehog R-HSA-5358351
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent DNA Damage Response R-HSA-69610
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
HIV Infection R-HSA-162906
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCF dependent signaling in response to WNT R-HSA-201681
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Signaling by NOTCH4 R-HSA-9013694
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
Metabolism of proteins R-HSA-392499
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'on' state R-HSA-5632684
Gene expression (Transcription) R-HSA-74160
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Adaptive Immune System R-HSA-1280218
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing-Cross presentation R-HSA-1236975
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
RAF/MAP kinase cascade R-HSA-5673001
Class I MHC mediated antigen processing & presentation R-HSA-983169
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants are degraded by ERAD R-HSA-5362768
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to chemical stress R-HSA-9711123
Post-translational protein modification R-HSA-597592
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
Transport of small molecules R-HSA-382551
Intracellular signaling by second messengers R-HSA-9006925
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Infectious disease R-HSA-5663205
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ABC-family proteins mediated transport R-HSA-382556
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Post-translational protein modification R-HSA-597592
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
Host Interactions of HIV factors R-HSA-162909
S Phase R-HSA-69242
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin E associated events during G1/S transition R-HSA-69202
Programmed Cell Death R-HSA-5357801
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Hh mutants abrogate ligand secretion R-HSA-5387390
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX2 expression and activity R-HSA-8939902
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
Regulation of mitotic cell cycle R-HSA-453276
Synthesis of DNA R-HSA-69239
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stress R-HSA-2262752
Disorders of transmembrane transporters R-HSA-5619115
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
PCP/CE pathway R-HSA-4086400
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cell Cycle, Mitotic R-HSA-69278
Neddylation R-HSA-8951664
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation by RUNX1 R-HSA-8878171
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Innate Immune System R-HSA-168249
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vpu mediated degradation of CD4 R-HSA-180534
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
M Phase R-HSA-68886
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Regulation of PTEN stability and activity R-HSA-8948751
Nervous system development R-HSA-9675108
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX2 R-HSA-8878166
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of AXIN R-HSA-4641257
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
G2/M Transition R-HSA-69275
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
G1/S Transition R-HSA-69206
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
G2/M Checkpoints R-HSA-69481
Activation of NF-kappaB in B cells R-HSA-1169091
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI1 by the proteasome R-HSA-5610780
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic G1 phase and G1/S transition R-HSA-453279
Assembly of the pre-replicative complex R-HSA-68867
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
Hh mutants are degraded by ERAD R-HSA-5362768
Disorders of transmembrane transporters R-HSA-5619115
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nuclear events mediated by NFE2L2 R-HSA-9759194
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Apoptosis R-HSA-109581
Cellular response to hypoxia R-HSA-1234174
Regulation of RUNX3 expression and activity R-HSA-8941858
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC transporter disorders R-HSA-5619084
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1 DNA Damage Response R-HSA-69563
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'on' state R-HSA-5632684
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Generic Transcription Pathway R-HSA-212436
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
S Phase R-HSA-69242
RAF/MAP kinase cascade R-HSA-5673001
Deubiquitination R-HSA-5688426
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'off' state R-HSA-5610787
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Mitotic Metaphase and Anaphase R-HSA-2555396
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
ER-Phagosome pathway R-HSA-1236974
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
Intracellular signaling by second messengers R-HSA-9006925
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Activation of NF-kappaB in B cells R-HSA-1169091
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle Checkpoints R-HSA-69620
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Metaphase and Anaphase R-HSA-2555396
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
PCP/CE pathway R-HSA-4086400
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Anaphase R-HSA-68882
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular response to hypoxia R-HSA-1234174
MAPK6/MAPK4 signaling R-HSA-5687128
Switching of origins to a post-replicative state R-HSA-69052
Signaling by WNT R-HSA-195721
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Activation of NF-kappaB in B cells R-HSA-1169091
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
KEAP1-NFE2L2 pathway R-HSA-9755511
Assembly of the pre-replicative complex R-HSA-68867
Axon guidance R-HSA-422475
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RUNX3 expression and activity R-HSA-8941858
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
Transport of small molecules R-HSA-382551
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Apoptosis R-HSA-109581
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hh mutants are degraded by ERAD R-HSA-5362768
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ER-Phagosome pathway R-HSA-1236974
Infectious disease R-HSA-5663205
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI1 by the proteasome R-HSA-5610780
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Signal Transduction R-HSA-162582
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Disorders of transmembrane transporters R-HSA-5619115
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH4 R-HSA-9013694
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vpu mediated degradation of CD4 R-HSA-180534
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
Degradation of AXIN R-HSA-4641257
Signaling by Interleukins R-HSA-449147
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX3 expression and activity R-HSA-8941858
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK6/MAPK4 signaling R-HSA-5687128
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323

Expression Atlas ENSG00000126067
NCBI gene (formerly Entrezgene) 5690
GeneCards 9539
HGNC Symbol HGNC:9539
MIM gene 602175
UniProtKB Gene Name P49721
WikiGene 5690
Gene: PSMB3
Ensembl ID : ENSG00000277791
Description: proteasome 20S subunit beta 3
Gene Synonyms: HC10-II,MGC4147
6 APIs:
240 Possible Orthologues:

Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
S Phase R-HSA-69242
Metabolism of proteins R-HSA-392499
Orc1 removal from chromatin R-HSA-68949
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Disease R-HSA-1643685
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by Hedgehog R-HSA-5358351
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle, Mitotic R-HSA-69278
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
PTEN Regulation R-HSA-6807070
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
M Phase R-HSA-68886
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Cellular responses to stress R-HSA-2262752
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by WNT R-HSA-195721
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of RNA R-HSA-8953854
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Signaling by ROBO receptors R-HSA-376176
Nervous system development R-HSA-9675108
Stabilization of p53 R-HSA-69541
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
C-type lectin receptors (CLRs) R-HSA-5621481
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Hedgehog ligand biogenesis R-HSA-5358346
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
Cell Cycle R-HSA-1640170
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Post-translational protein modification R-HSA-597592
TCF dependent signaling in response to WNT R-HSA-201681
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PCP/CE pathway R-HSA-4086400
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication R-HSA-69306
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ABC transporter disorders R-HSA-5619084
KEAP1-NFE2L2 pathway R-HSA-9755511
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Host Interactions of HIV factors R-HSA-162909
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Developmental Biology R-HSA-1266738
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Checkpoints R-HSA-69481
Neddylation R-HSA-8951664
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RAF/MAP kinase cascade R-HSA-5673001
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH R-HSA-157118
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of DVL R-HSA-4641258
PCP/CE pathway R-HSA-4086400
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
Beta-catenin independent WNT signaling R-HSA-3858494
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI2 by the proteasome R-HSA-5610783
Developmental Biology R-HSA-1266738
G1/S Transition R-HSA-69206
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Orc1 removal from chromatin R-HSA-68949
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
TCR signaling R-HSA-202403
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
UCH proteinases R-HSA-5689603
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Interleukin-1 family signaling R-HSA-446652
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Axon guidance R-HSA-422475
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FCERI mediated NF-kB activation R-HSA-2871837
Apoptosis R-HSA-109581
Mitotic Anaphase R-HSA-68882
Degradation of GLI1 by the proteasome R-HSA-5610780
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX2 R-HSA-8878166
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
PIP3 activates AKT signaling R-HSA-1257604
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication Pre-Initiation R-HSA-69002
Generic Transcription Pathway R-HSA-212436
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RNA Polymerase II Transcription R-HSA-73857
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Interleukin-1 signaling R-HSA-9020702
Host Interactions of HIV factors R-HSA-162909
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RUNX2 expression and activity R-HSA-8939902
Immune System R-HSA-168256
Disease R-HSA-1643685
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Generic Transcription Pathway R-HSA-212436
Disorders of transmembrane transporters R-HSA-5619115
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX2 R-HSA-8878166
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RUNX2 expression and activity R-HSA-8939902
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog 'on' state R-HSA-5632684
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
Assembly of the pre-replicative complex R-HSA-68867
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of DVL R-HSA-4641258
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Axon guidance R-HSA-422475
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic G1 phase and G1/S transition R-HSA-453279
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Cell Cycle Checkpoints R-HSA-69620
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Programmed Cell Death R-HSA-5357801
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of RNA R-HSA-8953854
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Stabilization of p53 R-HSA-69541
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants abrogate ligand secretion R-HSA-5387390
TCR signaling R-HSA-202403
Immune System R-HSA-168256
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Checkpoints R-HSA-69481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular response to chemical stress R-HSA-9711123
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by ROBO receptors R-HSA-376176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Axon guidance R-HSA-422475
Post-translational protein modification R-HSA-597592
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX1 R-HSA-8878171
ER-Phagosome pathway R-HSA-1236974
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RAS by GAPs R-HSA-5658442
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
Synthesis of DNA R-HSA-69239
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
S Phase R-HSA-69242
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX3 R-HSA-8878159
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G1 phase and G1/S transition R-HSA-453279
PIP3 activates AKT signaling R-HSA-1257604
Degradation of DVL R-HSA-4641258
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
Apoptosis R-HSA-109581
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Hh mutants are degraded by ERAD R-HSA-5362768
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
Nervous system development R-HSA-9675108
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Metaphase and Anaphase R-HSA-2555396
PCP/CE pathway R-HSA-4086400
Cell Cycle R-HSA-1640170
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Stabilization of p53 R-HSA-69541
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Orc1 removal from chromatin R-HSA-68949
Asymmetric localization of PCP proteins R-HSA-4608870
Innate Immune System R-HSA-168249
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle Checkpoints R-HSA-69620
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
Cytokine Signaling in Immune system R-HSA-1280215
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PTEN Regulation R-HSA-6807070
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by NOTCH R-HSA-157118
Interleukin-1 family signaling R-HSA-446652
Cellular response to chemical stress R-HSA-9711123
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Switching of origins to a post-replicative state R-HSA-69052
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle R-HSA-1640170
Hedgehog 'on' state R-HSA-5632684
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Signaling by Hedgehog R-HSA-5358351
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S Transition R-HSA-69206
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RAF/MAP kinase cascade R-HSA-5673001
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ABC transporter disorders R-HSA-5619084
Mitotic Anaphase R-HSA-68882
Nervous system development R-HSA-9675108
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC-family proteins mediated transport R-HSA-382556
MAPK family signaling cascades R-HSA-5683057
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Separation of Sister Chromatids R-HSA-2467813
Regulation of PTEN stability and activity R-HSA-8948751
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
S Phase R-HSA-69242
Signaling by ROBO receptors R-HSA-376176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle, Mitotic R-HSA-69278
Axon guidance R-HSA-422475
Antigen processing-Cross presentation R-HSA-1236975
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX3 expression and activity R-HSA-8941858
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle Checkpoints R-HSA-69620
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stress R-HSA-2262752
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disease R-HSA-1643685
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Host Interactions of HIV factors R-HSA-162909
Signaling by NOTCH4 R-HSA-9013694
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ub-specific processing proteases R-HSA-5689880
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
TCF dependent signaling in response to WNT R-HSA-201681
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Metabolism R-HSA-1430728
M Phase R-HSA-68886
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by WNT R-HSA-195721
Transport of small molecules R-HSA-382551
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Adaptive Immune System R-HSA-1280218
Ub-specific processing proteases R-HSA-5689880
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
G1/S DNA Damage Checkpoints R-HSA-69615
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by Interleukins R-HSA-449147
Separation of Sister Chromatids R-HSA-2467813
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication R-HSA-69306
Vif-mediated degradation of APOBEC3G R-HSA-180585
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle, Mitotic R-HSA-69278
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by WNT R-HSA-195721
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Antigen processing-Cross presentation R-HSA-1236975
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of polyamines R-HSA-351202
Developmental Biology R-HSA-1266738
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'on' state R-HSA-5632684
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PTEN Regulation R-HSA-6807070
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of GLI1 by the proteasome R-HSA-5610780
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle Checkpoints R-HSA-69620
Cytokine Signaling in Immune system R-HSA-1280215
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RNA Polymerase II Transcription R-HSA-73857
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
Downstream TCR signaling R-HSA-202424
Innate Immune System R-HSA-168249
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
Post-translational protein modification R-HSA-597592
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 family signaling R-HSA-446652
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Intracellular signaling by second messengers R-HSA-9006925
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
M Phase R-HSA-68886
Metabolism R-HSA-1430728
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of DVL R-HSA-4641258
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX3 R-HSA-8878159
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH4 R-HSA-9013694
Metabolism R-HSA-1430728
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of proteins R-HSA-392499
ABC transporter disorders R-HSA-5619084
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disease R-HSA-1643685
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Separation of Sister Chromatids R-HSA-2467813
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
G2/M Checkpoints R-HSA-69481
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants are degraded by ERAD R-HSA-5362768
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
DNA Replication Pre-Initiation R-HSA-69002
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog ligand biogenesis R-HSA-5358346
Post-translational protein modification R-HSA-597592
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
M Phase R-HSA-68886
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle Checkpoints R-HSA-69620
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
G1/S Transition R-HSA-69206
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of DVL R-HSA-4641258
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
Developmental Biology R-HSA-1266738
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Nervous system development R-HSA-9675108
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Apoptosis R-HSA-109581
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
PIP3 activates AKT signaling R-HSA-1257604
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
UCH proteinases R-HSA-5689603
PTEN Regulation R-HSA-6807070
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Post-translational protein modification R-HSA-597592
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
PTEN Regulation R-HSA-6807070
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
Signaling by NOTCH R-HSA-157118
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX3 expression and activity R-HSA-8941858
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of polyamines R-HSA-351202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Adaptive Immune System R-HSA-1280218
PCP/CE pathway R-HSA-4086400
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Interleukin-1 signaling R-HSA-9020702
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stress R-HSA-2262752
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
Signal Transduction R-HSA-162582
Apoptosis R-HSA-109581
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RAS by GAPs R-HSA-5658442
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular response to chemical stress R-HSA-9711123
G1/S Transition R-HSA-69206
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK family signaling cascades R-HSA-5683057
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'off' state R-HSA-5610787
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
Synthesis of DNA R-HSA-69239
Hh mutants abrogate ligand secretion R-HSA-5387390
Disease R-HSA-1643685
Host Interactions of HIV factors R-HSA-162909
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Developmental Biology R-HSA-1266738
Degradation of DVL R-HSA-4641258
Disorders of transmembrane transporters R-HSA-5619115
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic G2-G2/M phases R-HSA-453274
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
Interleukin-1 family signaling R-HSA-446652
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of PTEN stability and activity R-HSA-8948751
Transport of small molecules R-HSA-382551
Axon guidance R-HSA-422475
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vif-mediated degradation of APOBEC3G R-HSA-180585
Adaptive Immune System R-HSA-1280218
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
Class I MHC mediated antigen processing & presentation R-HSA-983169
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
HIV Infection R-HSA-162906
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH4 R-HSA-9013694
Neddylation R-HSA-8951664
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
PIP3 activates AKT signaling R-HSA-1257604
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S Transition R-HSA-69206
PCP/CE pathway R-HSA-4086400
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Metabolism of polyamines R-HSA-351202
Mitotic Metaphase and Anaphase R-HSA-2555396
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mitotic cell cycle R-HSA-453276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
Metabolism of RNA R-HSA-8953854
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Anaphase R-HSA-68882
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Cytokine Signaling in Immune system R-HSA-1280215
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle, Mitotic R-HSA-69278
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Signaling by Hedgehog R-HSA-5358351
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication Pre-Initiation R-HSA-69002
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of beta-catenin by the destruction complex R-HSA-195253
PTEN Regulation R-HSA-6807070
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Generic Transcription Pathway R-HSA-212436
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to chemical stress R-HSA-9711123
Cellular response to hypoxia R-HSA-1234174
Cellular responses to stress R-HSA-2262752
Hedgehog 'off' state R-HSA-5610787
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
M Phase R-HSA-68886
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Degradation of GLI1 by the proteasome R-HSA-5610780
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
S Phase R-HSA-69242
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
Assembly of the pre-replicative complex R-HSA-68867
Nuclear events mediated by NFE2L2 R-HSA-9759194
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic Anaphase R-HSA-68882
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of polyamines R-HSA-351202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI2 by the proteasome R-HSA-5610783
Vif-mediated degradation of APOBEC3G R-HSA-180585
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Gene expression (Transcription) R-HSA-74160
Infectious disease R-HSA-5663205
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1 DNA Damage Response R-HSA-69563
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
S Phase R-HSA-69242
Hedgehog 'off' state R-HSA-5610787
Cyclin E associated events during G1/S transition R-HSA-69202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Transcriptional regulation by RUNX1 R-HSA-8878171
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Orc1 removal from chromatin R-HSA-68949
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Asymmetric localization of PCP proteins R-HSA-4608870
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of DVL R-HSA-4641258
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
Nuclear events mediated by NFE2L2 R-HSA-9759194
Beta-catenin independent WNT signaling R-HSA-3858494
Nervous system development R-HSA-9675108
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 signaling R-HSA-9020702
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Transport of small molecules R-HSA-382551
Post-translational protein modification R-HSA-597592
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Stabilization of p53 R-HSA-69541
Transcriptional regulation by RUNX2 R-HSA-8878166
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Signaling by ROBO receptors R-HSA-376176
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G2-G2/M phases R-HSA-453274
Adaptive Immune System R-HSA-1280218
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stimuli R-HSA-8953897
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Disorders of transmembrane transporters R-HSA-5619115
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1 DNA Damage Response R-HSA-69563
M Phase R-HSA-68886
Intracellular signaling by second messengers R-HSA-9006925
Beta-catenin independent WNT signaling R-HSA-3858494
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Neddylation R-HSA-8951664
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mitotic cell cycle R-HSA-453276
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Mitotic Anaphase R-HSA-68882
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of AXIN R-HSA-4641257
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
ABC-family proteins mediated transport R-HSA-382556
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX1 R-HSA-8878171
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
ER-Phagosome pathway R-HSA-1236974
Metabolism of amino acids and derivatives R-HSA-71291
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Programmed Cell Death R-HSA-5357801
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication Pre-Initiation R-HSA-69002
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
MAPK family signaling cascades R-HSA-5683057
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ROBO receptors R-HSA-376176
G2/M Transition R-HSA-69275
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Interleukin-1 signaling R-HSA-9020702
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC transporter disorders R-HSA-5619084
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Post-translational protein modification R-HSA-597592
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
G1/S Transition R-HSA-69206
Signaling by NOTCH4 R-HSA-9013694
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091

Expression Atlas ENSG00000277791
NCBI gene (formerly Entrezgene) 5691
GeneCards 9540
HGNC Symbol HGNC:9540
MIM gene 602176
UniProtKB Gene Name P49720
WikiGene 5691
Gene: PSMB9
Ensembl ID : ENSG00000240065
Description: proteasome 20S subunit beta 9
Gene Synonyms: BETA1I,LMP2,PSMB6I,RING12
6 APIs:
214 Possible Orthologues:

HIV Infection R-HSA-162906
HIV Infection R-HSA-162906
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PIP3 activates AKT signaling R-HSA-1257604
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
DNA Replication R-HSA-69306
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
ER-Phagosome pathway R-HSA-1236974
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RNA Polymerase II Transcription R-HSA-73857
Signaling by Hedgehog R-HSA-5358351
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by WNT R-HSA-195721
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by NOTCH4 R-HSA-9013694
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of DVL R-HSA-4641258
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Neddylation R-HSA-8951664
Hedgehog ligand biogenesis R-HSA-5358346
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog 'on' state R-HSA-5632684
G1/S Transition R-HSA-69206
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Interleukin-1 signaling R-HSA-9020702
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Anaphase R-HSA-68882
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
Transport of small molecules R-HSA-382551
Gene expression (Transcription) R-HSA-74160
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Intracellular signaling by second messengers R-HSA-9006925
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI2 by the proteasome R-HSA-5610783
Class I MHC mediated antigen processing & presentation R-HSA-983169
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RAS by GAPs R-HSA-5658442
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Hedgehog 'off' state R-HSA-5610787
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to chemical stress R-HSA-9711123
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
HIV Infection R-HSA-162906
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
Antigen processing-Cross presentation R-HSA-1236975
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism R-HSA-1430728
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of RNA R-HSA-8953854
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S Transition R-HSA-69206
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hedgehog 'off' state R-HSA-5610787
Asymmetric localization of PCP proteins R-HSA-4608870
ER-Phagosome pathway R-HSA-1236974
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 family signaling R-HSA-446652
Stabilization of p53 R-HSA-69541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G2/M Checkpoints R-HSA-69481
Cell Cycle, Mitotic R-HSA-69278
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
RAF/MAP kinase cascade R-HSA-5673001
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
Switching of origins to a post-replicative state R-HSA-69052
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Transition R-HSA-69275
Nuclear events mediated by NFE2L2 R-HSA-9759194
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
S Phase R-HSA-69242
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
Deubiquitination R-HSA-5688426
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Developmental Biology R-HSA-1266738
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Axon guidance R-HSA-422475
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Interleukin-1 signaling R-HSA-9020702
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
RNA Polymerase II Transcription R-HSA-73857
Degradation of DVL R-HSA-4641258
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX3 R-HSA-8878159
Post-translational protein modification R-HSA-597592
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
M Phase R-HSA-68886
MAPK1/MAPK3 signaling R-HSA-5684996
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of NF-kappaB in B cells R-HSA-1169091
Synthesis of DNA R-HSA-69239
Mitotic G1 phase and G1/S transition R-HSA-453279
Hh mutants are degraded by ERAD R-HSA-5362768
Class I MHC mediated antigen processing & presentation R-HSA-983169
M Phase R-HSA-68886
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Axon guidance R-HSA-422475
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1 DNA Damage Response R-HSA-69563
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Separation of Sister Chromatids R-HSA-2467813
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication R-HSA-69306
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Innate Immune System R-HSA-168249
Hedgehog 'on' state R-HSA-5632684
Metabolism R-HSA-1430728
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication Pre-Initiation R-HSA-69002
Degradation of AXIN R-HSA-4641257
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
PIP3 activates AKT signaling R-HSA-1257604
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI2 by the proteasome R-HSA-5610783
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
Disorders of transmembrane transporters R-HSA-5619115
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
Signal Transduction R-HSA-162582
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
ABC-family proteins mediated transport R-HSA-382556
MAPK6/MAPK4 signaling R-HSA-5687128
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular responses to stress R-HSA-2262752
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
Ub-specific processing proteases R-HSA-5689880
TCF dependent signaling in response to WNT R-HSA-201681
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 family signaling R-HSA-446652
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Hedgehog 'off' state R-HSA-5610787
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NOTCH R-HSA-157118
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
G1/S DNA Damage Checkpoints R-HSA-69615
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
Transport of small molecules R-HSA-382551
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PTEN Regulation R-HSA-6807070
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
G2/M Transition R-HSA-69275
Developmental Biology R-HSA-1266738
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Asymmetric localization of PCP proteins R-HSA-4608870
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH R-HSA-157118
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
KEAP1-NFE2L2 pathway R-HSA-9755511
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Antigen processing-Cross presentation R-HSA-1236975
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by NOTCH4 R-HSA-9013694
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Activation of NF-kappaB in B cells R-HSA-1169091
UCH proteinases R-HSA-5689603
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S Transition R-HSA-69206
ER-Phagosome pathway R-HSA-1236974
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
MAPK6/MAPK4 signaling R-HSA-5687128
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of Apoptosis R-HSA-169911
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mitotic cell cycle R-HSA-453276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ABC transporter disorders R-HSA-5619084
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog ligand biogenesis R-HSA-5358346
Beta-catenin independent WNT signaling R-HSA-3858494
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vif-mediated degradation of APOBEC3G R-HSA-180585
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nervous system development R-HSA-9675108
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
DNA Replication Pre-Initiation R-HSA-69002
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Signaling by ROBO receptors R-HSA-376176
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Synthesis of DNA R-HSA-69239
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC-family proteins mediated transport R-HSA-382556
Gene expression (Transcription) R-HSA-74160
Degradation of DVL R-HSA-4641258
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
Degradation of AXIN R-HSA-4641257
Switching of origins to a post-replicative state R-HSA-69052
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Interleukin-1 signaling R-HSA-9020702
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin E associated events during G1/S transition R-HSA-69202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
M Phase R-HSA-68886
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
G1/S DNA Damage Checkpoints R-HSA-69615
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to hypoxia R-HSA-1234174
Defective CFTR causes cystic fibrosis R-HSA-5678895
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cytokine Signaling in Immune system R-HSA-1280215
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Degradation of GLI2 by the proteasome R-HSA-5610783
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Nuclear events mediated by NFE2L2 R-HSA-9759194
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Signaling by Hedgehog R-HSA-5358351
DNA Replication Pre-Initiation R-HSA-69002
Separation of Sister Chromatids R-HSA-2467813
Gene expression (Transcription) R-HSA-74160
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by Interleukins R-HSA-449147
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
MAPK1/MAPK3 signaling R-HSA-5684996
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vpu mediated degradation of CD4 R-HSA-180534
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular response to chemical stress R-HSA-9711123
PCP/CE pathway R-HSA-4086400
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX2 expression and activity R-HSA-8939902
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Disease R-HSA-1643685
M Phase R-HSA-68886
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI1 by the proteasome R-HSA-5610780
Innate Immune System R-HSA-168249
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Adaptive Immune System R-HSA-1280218
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle Checkpoints R-HSA-69620
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
UCH proteinases R-HSA-5689603
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Metabolism R-HSA-1430728
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
ABC-family proteins mediated transport R-HSA-382556
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants are degraded by ERAD R-HSA-5362768
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
Programmed Cell Death R-HSA-5357801
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
Synthesis of DNA R-HSA-69239
Signaling by WNT R-HSA-195721
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Generic Transcription Pathway R-HSA-212436
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
Class I MHC mediated antigen processing & presentation R-HSA-983169
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
Separation of Sister Chromatids R-HSA-2467813
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog ligand biogenesis R-HSA-5358346
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX1 R-HSA-8878171
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of PTEN stability and activity R-HSA-8948751
ABC-family proteins mediated transport R-HSA-382556
Regulation of mitotic cell cycle R-HSA-453276
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'on' state R-HSA-5632684
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by Hedgehog R-HSA-5358351
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Nuclear events mediated by NFE2L2 R-HSA-9759194
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Activation of NF-kappaB in B cells R-HSA-1169091
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
Transport of small molecules R-HSA-382551
Cellular responses to stimuli R-HSA-8953897
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Programmed Cell Death R-HSA-5357801
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Orc1 removal from chromatin R-HSA-68949
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
NIK-->noncanonical NF-kB signaling R-HSA-5676590
DNA Replication R-HSA-69306
Cellular response to chemical stress R-HSA-9711123
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Post-translational protein modification R-HSA-597592
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
p53-Independent DNA Damage Response R-HSA-69610
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of Apoptosis R-HSA-169911
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by WNT R-HSA-195721
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of AXIN R-HSA-4641257
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Gene expression (Transcription) R-HSA-74160
Cellular response to chemical stress R-HSA-9711123
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nervous system development R-HSA-9675108
UCH proteinases R-HSA-5689603
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog ligand biogenesis R-HSA-5358346
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Checkpoints R-HSA-69481
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RNA Polymerase II Transcription R-HSA-73857
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
Developmental Biology R-HSA-1266738
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
PCP/CE pathway R-HSA-4086400
Stabilization of p53 R-HSA-69541
Nuclear events mediated by NFE2L2 R-HSA-9759194
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
Host Interactions of HIV factors R-HSA-162909
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
Axon guidance R-HSA-422475
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK1/MAPK3 signaling R-HSA-5684996
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Adaptive Immune System R-HSA-1280218
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G1/S DNA Damage Checkpoints R-HSA-69615
Downstream TCR signaling R-HSA-202424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Disease R-HSA-1643685
G2/M Transition R-HSA-69275
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of Apoptosis R-HSA-169911
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog 'off' state R-HSA-5610787
Regulation of RAS by GAPs R-HSA-5658442
G1/S Transition R-HSA-69206
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of proteins R-HSA-392499
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Apoptosis R-HSA-109581
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK family signaling cascades R-HSA-5683057
C-type lectin receptors (CLRs) R-HSA-5621481
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to hypoxia R-HSA-1234174
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Independent DNA Damage Response R-HSA-69610
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
PCP/CE pathway R-HSA-4086400
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
S Phase R-HSA-69242
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
DNA Replication Pre-Initiation R-HSA-69002
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
UCH proteinases R-HSA-5689603
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Deubiquitination R-HSA-5688426
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
M Phase R-HSA-68886
Ub-specific processing proteases R-HSA-5689880
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
PIP3 activates AKT signaling R-HSA-1257604
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G2/M Checkpoints R-HSA-69481
Degradation of DVL R-HSA-4641258
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Transition R-HSA-69275
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Disorders of transmembrane transporters R-HSA-5619115
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle R-HSA-1640170
Cyclin E associated events during G1/S transition R-HSA-69202
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Post-translational protein modification R-HSA-597592
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX1 R-HSA-8878171
Vif-mediated degradation of APOBEC3G R-HSA-180585
Developmental Biology R-HSA-1266738
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle, Mitotic R-HSA-69278
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of RNA R-HSA-8953854
Neddylation R-HSA-8951664
Immune System R-HSA-168256
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Disease R-HSA-1643685
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular response to chemical stress R-HSA-9711123
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants abrogate ligand secretion R-HSA-5387390
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular response to hypoxia R-HSA-1234174
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Infectious disease R-HSA-5663205
Regulation of Apoptosis R-HSA-169911
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Axon guidance R-HSA-422475
Immune System R-HSA-168256
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ABC-family proteins mediated transport R-HSA-382556
Regulation of RAS by GAPs R-HSA-5658442
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent DNA Damage Response R-HSA-69610
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ub-specific processing proteases R-HSA-5689880
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
HIV Infection R-HSA-162906
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic Metaphase and Anaphase R-HSA-2555396
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
Metabolism of RNA R-HSA-8953854
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Post-translational protein modification R-HSA-597592
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
Regulation of mitotic cell cycle R-HSA-453276
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH4 R-HSA-9013694
Transport of small molecules R-HSA-382551
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
DNA Replication R-HSA-69306
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Gene expression (Transcription) R-HSA-74160
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
Beta-catenin independent WNT signaling R-HSA-3858494
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle R-HSA-1640170
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274

Expression Atlas ENSG00000240065
NCBI gene (formerly Entrezgene) 5698
GeneCards 9546
HGNC Symbol HGNC:9546
MIM gene 177045
MIM morbid 617591
UniProtKB Gene Name P28065
WikiGene 5698
Gene: MCL1
Ensembl ID : ENSG00000143384
Description: MCL1 apoptosis regulator, BCL2 family member
Gene Synonyms: BCL2L3,MCL-1
1 APIs:
243 Possible Orthologues:

Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256

Expression Atlas ENSG00000143384
NCBI gene (formerly Entrezgene) 574406
GeneCards 6943
HGNC Symbol HGNC:6943
MIM gene 159552
UniProtKB Gene Name Q07820
WikiGene 574406
Gene: PSMC1
Ensembl ID : ENSG00000100764
Description: proteasome 26S subunit, ATPase 1
Gene Synonyms: P56,RPT2,S4
5 APIs:
264 Possible Orthologues:

S Phase R-HSA-69242
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism of RNA R-HSA-8953854
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX3 R-HSA-8878159
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Cyclin E associated events during G1/S transition R-HSA-69202
Separation of Sister Chromatids R-HSA-2467813
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication R-HSA-69306
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
C-type lectin receptors (CLRs) R-HSA-5621481
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cellular response to hypoxia R-HSA-1234174
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'on' state R-HSA-5632684
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Cellular responses to stress R-HSA-2262752
Vif-mediated degradation of APOBEC3G R-HSA-180585
Orc1 removal from chromatin R-HSA-68949
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Developmental Biology R-HSA-1266738
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism R-HSA-1430728
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream TCR signaling R-HSA-202424
Cell Cycle Checkpoints R-HSA-69620
Nuclear events mediated by NFE2L2 R-HSA-9759194
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Axon guidance R-HSA-422475
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
Asparagine N-linked glycosylation R-HSA-446203
Disorders of transmembrane transporters R-HSA-5619115
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Apoptosis R-HSA-109581
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
Host Interactions of HIV factors R-HSA-162909
Programmed Cell Death R-HSA-5357801
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
PCP/CE pathway R-HSA-4086400
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by WNT R-HSA-195721
Regulation of mitotic cell cycle R-HSA-453276
ER-Phagosome pathway R-HSA-1236974
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of GLI1 by the proteasome R-HSA-5610780
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
HIV Infection R-HSA-162906
Disease R-HSA-1643685
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of polyamines R-HSA-351202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Apoptosis R-HSA-109581
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
ER-Phagosome pathway R-HSA-1236974
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH R-HSA-157118
Metabolism of proteins R-HSA-392499
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication R-HSA-69306
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
M Phase R-HSA-68886
G1/S Transition R-HSA-69206
Beta-catenin independent WNT signaling R-HSA-3858494
Assembly of the pre-replicative complex R-HSA-68867
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
RAF/MAP kinase cascade R-HSA-5673001
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
Cell Cycle, Mitotic R-HSA-69278
Asparagine N-linked glycosylation R-HSA-446203
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ROBO receptors R-HSA-376176
Cellular response to hypoxia R-HSA-1234174
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
ABC-family proteins mediated transport R-HSA-382556
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
UCH proteinases R-HSA-5689603
MAPK family signaling cascades R-HSA-5683057
ABC transporter disorders R-HSA-5619084
Hh mutants abrogate ligand secretion R-HSA-5387390
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
PTEN Regulation R-HSA-6807070
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
Infectious disease R-HSA-5663205
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCR signaling R-HSA-202403
Negative regulation of NOTCH4 signaling R-HSA-9604323
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of RNA R-HSA-8953854
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vpu mediated degradation of CD4 R-HSA-180534
Intracellular signaling by second messengers R-HSA-9006925
Stabilization of p53 R-HSA-69541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'on' state R-HSA-5632684
Antigen processing-Cross presentation R-HSA-1236975
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by WNT R-HSA-195721
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI1 by the proteasome R-HSA-5610780
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog ligand biogenesis R-HSA-5358346
Separation of Sister Chromatids R-HSA-2467813
MAPK6/MAPK4 signaling R-HSA-5687128
Cell Cycle R-HSA-1640170
Degradation of DVL R-HSA-4641258
Deubiquitination R-HSA-5688426
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RAS by GAPs R-HSA-5658442
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCF dependent signaling in response to WNT R-HSA-201681
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of amino acids and derivatives R-HSA-71291
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mitotic cell cycle R-HSA-453276
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
Mitotic G2-G2/M phases R-HSA-453274
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Innate Immune System R-HSA-168249
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
UCH proteinases R-HSA-5689603
Disease R-HSA-1643685
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 signaling R-HSA-9020702
PCP/CE pathway R-HSA-4086400
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Apoptosis R-HSA-109581
Ub-specific processing proteases R-HSA-5689880
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Regulation of Apoptosis R-HSA-169911
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Negative regulation of NOTCH4 signaling R-HSA-9604323
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Cell Cycle Checkpoints R-HSA-69620
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
PIP3 activates AKT signaling R-HSA-1257604
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Asparagine N-linked glycosylation R-HSA-446203
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Synthesis of DNA R-HSA-69239
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
G1/S DNA Damage Checkpoints R-HSA-69615
Asymmetric localization of PCP proteins R-HSA-4608870
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Switching of origins to a post-replicative state R-HSA-69052
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism R-HSA-1430728
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH R-HSA-157118
C-type lectin receptors (CLRs) R-HSA-5621481
RNA Polymerase II Transcription R-HSA-73857
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
Mitotic Anaphase R-HSA-68882
G1/S Transition R-HSA-69206
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to chemical stress R-HSA-9711123
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Hedgehog R-HSA-5358351
DNA Replication Pre-Initiation R-HSA-69002
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'on' state R-HSA-5632684
Signal Transduction R-HSA-162582
Assembly of the pre-replicative complex R-HSA-68867
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Axon guidance R-HSA-422475
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Host Interactions of HIV factors R-HSA-162909
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
TCR signaling R-HSA-202403
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'off' state R-HSA-5610787
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nervous system development R-HSA-9675108
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Separation of Sister Chromatids R-HSA-2467813
G1/S Transition R-HSA-69206
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
CLEC7A (Dectin-1) signaling R-HSA-5607764
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
PCP/CE pathway R-HSA-4086400
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
DNA Replication R-HSA-69306
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
Cellular responses to stimuli R-HSA-8953897
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism R-HSA-1430728
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing-Cross presentation R-HSA-1236975
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Apoptosis R-HSA-109581
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Disorders of transmembrane transporters R-HSA-5619115
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
Asparagine N-linked glycosylation R-HSA-446203
Deubiquitination R-HSA-5688426
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
Gene expression (Transcription) R-HSA-74160
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Vpu mediated degradation of CD4 R-HSA-180534
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RNA Polymerase II Transcription R-HSA-73857
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCF dependent signaling in response to WNT R-HSA-201681
Transport of small molecules R-HSA-382551
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular responses to stress R-HSA-2262752
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
TCF dependent signaling in response to WNT R-HSA-201681
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of DVL R-HSA-4641258
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Post-translational protein modification R-HSA-597592
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Ub-specific processing proteases R-HSA-5689880
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Innate Immune System R-HSA-168249
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism R-HSA-1430728
PCP/CE pathway R-HSA-4086400
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transport of small molecules R-HSA-382551
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX3 R-HSA-8878159
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 signaling R-HSA-9020702
Signaling by ROBO receptors R-HSA-376176
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
G2/M Transition R-HSA-69275
Mitotic Anaphase R-HSA-68882
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Independent DNA Damage Response R-HSA-69610
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
Asparagine N-linked glycosylation R-HSA-446203
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
ER-Phagosome pathway R-HSA-1236974
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants are degraded by ERAD R-HSA-5362768
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by Hedgehog R-HSA-5358351
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FCERI mediated NF-kB activation R-HSA-2871837
M Phase R-HSA-68886
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of GLI2 by the proteasome R-HSA-5610783
Programmed Cell Death R-HSA-5357801
Cell Cycle Checkpoints R-HSA-69620
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
S Phase R-HSA-69242
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cytokine Signaling in Immune system R-HSA-1280215
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 family signaling R-HSA-446652
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Asymmetric localization of PCP proteins R-HSA-4608870
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic G1 phase and G1/S transition R-HSA-453279
ABC-family proteins mediated transport R-HSA-382556
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Disease R-HSA-1643685
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of Apoptosis R-HSA-169911
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Cellular response to chemical stress R-HSA-9711123
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of NF-kappaB in B cells R-HSA-1169091
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cytokine Signaling in Immune system R-HSA-1280215
Cell Cycle, Mitotic R-HSA-69278
G1/S Transition R-HSA-69206
Asparagine N-linked glycosylation R-HSA-446203
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Intracellular signaling by second messengers R-HSA-9006925
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Checkpoints R-HSA-69481
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Transition R-HSA-69275
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by ROBO receptors R-HSA-376176
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stress R-HSA-2262752
Switching of origins to a post-replicative state R-HSA-69052
Post-translational protein modification R-HSA-597592
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC transporter disorders R-HSA-5619084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of DVL R-HSA-4641258
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Synthesis of DNA R-HSA-69239
M Phase R-HSA-68886
PTEN Regulation R-HSA-6807070
Host Interactions of HIV factors R-HSA-162909
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Anaphase R-HSA-68882
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
ER-Phagosome pathway R-HSA-1236974
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mitotic cell cycle R-HSA-453276
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Interleukin-1 signaling R-HSA-9020702
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Interleukins R-HSA-449147
Signaling by WNT R-HSA-195721
Cell Cycle R-HSA-1640170
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
Regulation of RAS by GAPs R-HSA-5658442
Downstream TCR signaling R-HSA-202424
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX2 expression and activity R-HSA-8939902
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Asparagine N-linked glycosylation R-HSA-446203
Hedgehog ligand biogenesis R-HSA-5358346
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of proteins R-HSA-392499
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vif-mediated degradation of APOBEC3G R-HSA-180585
Class I MHC mediated antigen processing & presentation R-HSA-983169
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of polyamines R-HSA-351202
Axon guidance R-HSA-422475
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of DVL R-HSA-4641258
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Assembly of the pre-replicative complex R-HSA-68867
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Degradation of GLI2 by the proteasome R-HSA-5610783
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Deubiquitination R-HSA-5688426
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH R-HSA-157118
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX2 R-HSA-8878166
RAF/MAP kinase cascade R-HSA-5673001
ABC transporter disorders R-HSA-5619084
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Metaphase and Anaphase R-HSA-2555396
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transport of small molecules R-HSA-382551
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle R-HSA-1640170
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
G2/M Transition R-HSA-69275
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX2 expression and activity R-HSA-8939902
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Adaptive Immune System R-HSA-1280218
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 signaling R-HSA-9020702
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to chemical stress R-HSA-9711123
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Developmental Biology R-HSA-1266738
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
RAF/MAP kinase cascade R-HSA-5673001
Regulation of Apoptosis R-HSA-169911
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
ER-Phagosome pathway R-HSA-1236974
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Cellular responses to stress R-HSA-2262752
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of AXIN R-HSA-4641257
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
Immune System R-HSA-168256
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cyclin E associated events during G1/S transition R-HSA-69202
Asymmetric localization of PCP proteins R-HSA-4608870
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Asparagine N-linked glycosylation R-HSA-446203
Host Interactions of HIV factors R-HSA-162909
Degradation of DVL R-HSA-4641258
MAPK6/MAPK4 signaling R-HSA-5687128
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle R-HSA-1640170
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
M Phase R-HSA-68886
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Axon guidance R-HSA-422475
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Synthesis of DNA R-HSA-69239
G1/S Transition R-HSA-69206
Cellular response to hypoxia R-HSA-1234174
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G1 phase and G1/S transition R-HSA-453279
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle, Mitotic R-HSA-69278
Vif-mediated degradation of APOBEC3G R-HSA-180585
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RNA Polymerase II Transcription R-HSA-73857
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
CLEC7A (Dectin-1) signaling R-HSA-5607764
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX2 expression and activity R-HSA-8939902
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Separation of Sister Chromatids R-HSA-2467813
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Defective CFTR causes cystic fibrosis R-HSA-5678895
TCF dependent signaling in response to WNT R-HSA-201681
Developmental Biology R-HSA-1266738
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular responses to stimuli R-HSA-8953897
Degradation of AXIN R-HSA-4641257
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Regulation of RAS by GAPs R-HSA-5658442
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH4 R-HSA-9013694
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Axon guidance R-HSA-422475
Signaling by WNT R-HSA-195721
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
Stabilization of p53 R-HSA-69541
Intracellular signaling by second messengers R-HSA-9006925
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent DNA Damage Response R-HSA-69610
S Phase R-HSA-69242
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK family signaling cascades R-HSA-5683057
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Anaphase R-HSA-68882
PTEN Regulation R-HSA-6807070
ABC-family proteins mediated transport R-HSA-382556
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of RNA R-HSA-8953854
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Asparagine N-linked glycosylation R-HSA-446203
TCR signaling R-HSA-202403
Regulation of RUNX3 expression and activity R-HSA-8941858
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Hedgehog R-HSA-5358351
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream TCR signaling R-HSA-202424
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 signaling R-HSA-9020702
Post-translational protein modification R-HSA-597592
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S DNA Damage Checkpoints R-HSA-69615
HIV Infection R-HSA-162906
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
RAF/MAP kinase cascade R-HSA-5673001
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Assembly of the pre-replicative complex R-HSA-68867
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog ligand biogenesis R-HSA-5358346
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stress R-HSA-2262752
G1/S Transition R-HSA-69206
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
Metabolism R-HSA-1430728
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX2 expression and activity R-HSA-8939902
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism of proteins R-HSA-392499
G2/M Checkpoints R-HSA-69481
Signaling by Hedgehog R-HSA-5358351
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
Hedgehog 'off' state R-HSA-5610787
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Switching of origins to a post-replicative state R-HSA-69052
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Activation of NF-kappaB in B cells R-HSA-1169091
Assembly of the pre-replicative complex R-HSA-68867
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Asparagine N-linked glycosylation R-HSA-446203
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Adaptive Immune System R-HSA-1280218
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Intracellular signaling by second messengers R-HSA-9006925
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Apoptosis R-HSA-109581
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent DNA Damage Response R-HSA-69610
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
S Phase R-HSA-69242
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Host Interactions of HIV factors R-HSA-162909
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants are degraded by ERAD R-HSA-5362768
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of Apoptosis R-HSA-169911
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication R-HSA-69306
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Post-translational protein modification R-HSA-597592
G2/M Transition R-HSA-69275
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular response to chemical stress R-HSA-9711123
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
G1/S Transition R-HSA-69206
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of AXIN R-HSA-4641257
UCH proteinases R-HSA-5689603
Disorders of transmembrane transporters R-HSA-5619115
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
Mitotic G1 phase and G1/S transition R-HSA-453279
DNA Replication Pre-Initiation R-HSA-69002
MAPK6/MAPK4 signaling R-HSA-5687128
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
M Phase R-HSA-68886
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication R-HSA-69306
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Activation of NF-kappaB in B cells R-HSA-1169091
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Hedgehog R-HSA-5358351
MAPK6/MAPK4 signaling R-HSA-5687128
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Deubiquitination R-HSA-5688426
Hedgehog 'off' state R-HSA-5610787
Vif-mediated degradation of APOBEC3G R-HSA-180585
PIP3 activates AKT signaling R-HSA-1257604
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism R-HSA-1430728
S Phase R-HSA-69242
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
Apoptosis R-HSA-109581
TCF dependent signaling in response to WNT R-HSA-201681
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of RUNX3 expression and activity R-HSA-8941858
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of DVL R-HSA-4641258
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
Cytokine Signaling in Immune system R-HSA-1280215
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
RNA Polymerase II Transcription R-HSA-73857
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Hedgehog 'on' state R-HSA-5632684
Asparagine N-linked glycosylation R-HSA-446203
Signaling by WNT R-HSA-195721
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
PTEN Regulation R-HSA-6807070
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Metaphase and Anaphase R-HSA-2555396
Developmental Biology R-HSA-1266738
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of proteins R-HSA-392499
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neddylation R-HSA-8951664
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Generic Transcription Pathway R-HSA-212436
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of polyamines R-HSA-351202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Host Interactions of HIV factors R-HSA-162909
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of mitotic cell cycle R-HSA-453276
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
DNA Replication Pre-Initiation R-HSA-69002
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Synthesis of DNA R-HSA-69239
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Mitotic Anaphase R-HSA-68882
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Interleukin-1 signaling R-HSA-9020702
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114

Expression Atlas ENSG00000100764
NCBI gene (formerly Entrezgene) 5700
GeneCards 9547
HGNC Symbol HGNC:9547
MIM gene 602706
MIM morbid 620071
UniProtKB Gene Name Q53XL8
WikiGene 5700
Gene: PSMB8
Ensembl ID : ENSG00000204264
Description: proteasome 20S subunit beta 8
Gene Synonyms: BETA5I,D6S216E,LMP7,PSMB5I,RING10
6 APIs:
221 Possible Orthologues:

Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Synthesis of DNA R-HSA-69239
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
Switching of origins to a post-replicative state R-HSA-69052
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Interleukin-1 family signaling R-HSA-446652
Regulation of Apoptosis R-HSA-169911
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK family signaling cascades R-HSA-5683057
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Metabolism of amino acids and derivatives R-HSA-71291
MAPK1/MAPK3 signaling R-HSA-5684996
S Phase R-HSA-69242
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog ligand biogenesis R-HSA-5358346
Developmental Biology R-HSA-1266738
Orc1 removal from chromatin R-HSA-68949
Stabilization of p53 R-HSA-69541
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Cytokine Signaling in Immune system R-HSA-1280215
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
HIV Infection R-HSA-162906
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by WNT R-HSA-195721
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
G1/S Transition R-HSA-69206
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Mitotic G1 phase and G1/S transition R-HSA-453279
ER-Phagosome pathway R-HSA-1236974
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
Signaling by Interleukins R-HSA-449147
Interferon alpha/beta signaling R-HSA-909733
PIP3 activates AKT signaling R-HSA-1257604
UCH proteinases R-HSA-5689603
Cell Cycle Checkpoints R-HSA-69620
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Vpu mediated degradation of CD4 R-HSA-180534
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of polyamines R-HSA-351202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle, Mitotic R-HSA-69278
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
TCR signaling R-HSA-202403
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Independent DNA Damage Response R-HSA-69610
Interferon Signaling R-HSA-913531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
PCP/CE pathway R-HSA-4086400
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Defective CFTR causes cystic fibrosis R-HSA-5678895
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
M Phase R-HSA-68886
Degradation of AXIN R-HSA-4641257
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
DNA Replication Pre-Initiation R-HSA-69002
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Apoptosis R-HSA-109581
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
Vpu mediated degradation of CD4 R-HSA-180534
Neddylation R-HSA-8951664
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to chemical stress R-HSA-9711123
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Hedgehog R-HSA-5358351
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog ligand biogenesis R-HSA-5358346
Interferon Signaling R-HSA-913531
Generic Transcription Pathway R-HSA-212436
Interferon alpha/beta signaling R-HSA-909733
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Asymmetric localization of PCP proteins R-HSA-4608870
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
S Phase R-HSA-69242
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
Intracellular signaling by second messengers R-HSA-9006925
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of Apoptosis R-HSA-169911
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
FCERI mediated NF-kB activation R-HSA-2871837
Assembly of the pre-replicative complex R-HSA-68867
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH R-HSA-157118
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
Ub-specific processing proteases R-HSA-5689880
Degradation of DVL R-HSA-4641258
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
PCP/CE pathway R-HSA-4086400
Hh mutants are degraded by ERAD R-HSA-5362768
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Synthesis of DNA R-HSA-69239
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Gene expression (Transcription) R-HSA-74160
MAPK family signaling cascades R-HSA-5683057
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Beta-catenin independent WNT signaling R-HSA-3858494
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disorders of transmembrane transporters R-HSA-5619115
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ub-specific processing proteases R-HSA-5689880
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Transport of small molecules R-HSA-382551
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
Interferon alpha/beta signaling R-HSA-909733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interferon Signaling R-HSA-913531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Anaphase R-HSA-68882
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication Pre-Initiation R-HSA-69002
G1/S Transition R-HSA-69206
Developmental Biology R-HSA-1266738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
S Phase R-HSA-69242
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
p53-Independent DNA Damage Response R-HSA-69610
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
Hedgehog 'on' state R-HSA-5632684
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
Switching of origins to a post-replicative state R-HSA-69052
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
Metabolism of polyamines R-HSA-351202
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
Mitotic Metaphase and Anaphase R-HSA-2555396
Hedgehog ligand biogenesis R-HSA-5358346
Immune System R-HSA-168256
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PTEN Regulation R-HSA-6807070
M Phase R-HSA-68886
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Degradation of DVL R-HSA-4641258
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH R-HSA-157118
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Antigen processing-Cross presentation R-HSA-1236975
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
Adaptive Immune System R-HSA-1280218
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Interferon alpha/beta signaling R-HSA-909733
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of RUNX3 expression and activity R-HSA-8941858
G2/M Transition R-HSA-69275
MAPK6/MAPK4 signaling R-HSA-5687128
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Disorders of transmembrane transporters R-HSA-5619115
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Signaling by Interleukins R-HSA-449147
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
M Phase R-HSA-68886
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PCP/CE pathway R-HSA-4086400
Mitotic Anaphase R-HSA-68882
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Axon guidance R-HSA-422475
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX1 R-HSA-8878171
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Hedgehog 'on' state R-HSA-5632684
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neddylation R-HSA-8951664
Mitotic G2-G2/M phases R-HSA-453274
Post-translational protein modification R-HSA-597592
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PTEN Regulation R-HSA-6807070
Signaling by NOTCH4 R-HSA-9013694
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interferon Signaling R-HSA-913531
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Degradation of GLI1 by the proteasome R-HSA-5610780
Transport of small molecules R-HSA-382551
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
Interferon alpha/beta signaling R-HSA-909733
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Orc1 removal from chromatin R-HSA-68949
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RAF/MAP kinase cascade R-HSA-5673001
Ub-specific processing proteases R-HSA-5689880
Regulation of RAS by GAPs R-HSA-5658442
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PTEN Regulation R-HSA-6807070
Signaling by WNT R-HSA-195721
Regulation of PTEN stability and activity R-HSA-8948751
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
HIV Infection R-HSA-162906
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
Generic Transcription Pathway R-HSA-212436
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Vif-mediated degradation of APOBEC3G R-HSA-180585
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Synthesis of DNA R-HSA-69239
Signaling by NOTCH4 R-HSA-9013694
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
Switching of origins to a post-replicative state R-HSA-69052
MAPK1/MAPK3 signaling R-HSA-5684996
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 signaling R-HSA-9020702
Negative regulation of NOTCH4 signaling R-HSA-9604323
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 family signaling R-HSA-446652
PCP/CE pathway R-HSA-4086400
Transcriptional regulation by RUNX2 R-HSA-8878166
Nervous system development R-HSA-9675108
Interferon Signaling R-HSA-913531
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G1 phase and G1/S transition R-HSA-453279
Apoptosis R-HSA-109581
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin E associated events during G1/S transition R-HSA-69202
Neddylation R-HSA-8951664
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of AXIN R-HSA-4641257
Cellular response to hypoxia R-HSA-1234174
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Transition R-HSA-69275
G2/M Checkpoints R-HSA-69481
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G2/M Checkpoints R-HSA-69481
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RAS by GAPs R-HSA-5658442
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Interferon Signaling R-HSA-913531
Activation of NF-kappaB in B cells R-HSA-1169091
Antigen processing-Cross presentation R-HSA-1236975
Interferon alpha/beta signaling R-HSA-909733
Signaling by Hedgehog R-HSA-5358351
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
G2/M Transition R-HSA-69275
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mitotic cell cycle R-HSA-453276
RAF/MAP kinase cascade R-HSA-5673001
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of Apoptosis R-HSA-169911
Developmental Biology R-HSA-1266738
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Axon guidance R-HSA-422475
M Phase R-HSA-68886
Degradation of beta-catenin by the destruction complex R-HSA-195253
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle Checkpoints R-HSA-69620
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK1/MAPK3 signaling R-HSA-5684996
Post-translational protein modification R-HSA-597592
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
ABC transporter disorders R-HSA-5619084
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
PTEN Regulation R-HSA-6807070
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Signaling by NOTCH4 R-HSA-9013694
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Hedgehog ligand biogenesis R-HSA-5358346
S Phase R-HSA-69242
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK family signaling cascades R-HSA-5683057
TCF dependent signaling in response to WNT R-HSA-201681
UCH proteinases R-HSA-5689603
Interleukin-1 family signaling R-HSA-446652
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ub-specific processing proteases R-HSA-5689880
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Interferon Signaling R-HSA-913531
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interferon alpha/beta signaling R-HSA-909733
PTEN Regulation R-HSA-6807070
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Generic Transcription Pathway R-HSA-212436
Interleukin-1 signaling R-HSA-9020702
Infectious disease R-HSA-5663205
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Signaling by Interleukins R-HSA-449147
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Regulation of Apoptosis R-HSA-169911
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G1 phase and G1/S transition R-HSA-453279
Switching of origins to a post-replicative state R-HSA-69052
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Separation of Sister Chromatids R-HSA-2467813
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
KEAP1-NFE2L2 pathway R-HSA-9755511
Intracellular signaling by second messengers R-HSA-9006925
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Transition R-HSA-69275
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PIP3 activates AKT signaling R-HSA-1257604
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism of polyamines R-HSA-351202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'off' state R-HSA-5610787
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of RNA R-HSA-8953854
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of proteins R-HSA-392499
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of AXIN R-HSA-4641257
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
PIP3 activates AKT signaling R-HSA-1257604
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Host Interactions of HIV factors R-HSA-162909
Cell Cycle, Mitotic R-HSA-69278
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Apoptosis R-HSA-109581
Interferon Signaling R-HSA-913531
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Post-translational protein modification R-HSA-597592
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog ligand biogenesis R-HSA-5358346
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
G1/S Transition R-HSA-69206
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Generic Transcription Pathway R-HSA-212436
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RAF/MAP kinase cascade R-HSA-5673001
G2/M Transition R-HSA-69275
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
S Phase R-HSA-69242
Signaling by NOTCH4 R-HSA-9013694
Regulation of mitotic cell cycle R-HSA-453276
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Interferon alpha/beta signaling R-HSA-909733
Interleukin-1 family signaling R-HSA-446652
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
RNA Polymerase II Transcription R-HSA-73857
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic G2-G2/M phases R-HSA-453274
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
p53-Dependent G1 DNA Damage Response R-HSA-69563
Switching of origins to a post-replicative state R-HSA-69052
Developmental Biology R-HSA-1266738
Separation of Sister Chromatids R-HSA-2467813
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by WNT R-HSA-195721
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX3 expression and activity R-HSA-8941858
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
Cellular responses to stress R-HSA-2262752
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Metaphase and Anaphase R-HSA-2555396
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Cellular response to chemical stress R-HSA-9711123
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
Downstream TCR signaling R-HSA-202424
G1/S Transition R-HSA-69206
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Metabolism of amino acids and derivatives R-HSA-71291
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular responses to stimuli R-HSA-8953897
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
C-type lectin receptors (CLRs) R-HSA-5621481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Metabolism R-HSA-1430728
Interferon Signaling R-HSA-913531
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
Hh mutants are degraded by ERAD R-HSA-5362768
G2/M Checkpoints R-HSA-69481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interferon alpha/beta signaling R-HSA-909733
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Axon guidance R-HSA-422475
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
Cyclin E associated events during G1/S transition R-HSA-69202
Developmental Biology R-HSA-1266738
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
Host Interactions of HIV factors R-HSA-162909
Signaling by Hedgehog R-HSA-5358351
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signal Transduction R-HSA-162582
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Degradation of AXIN R-HSA-4641257
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
p53-Independent DNA Damage Response R-HSA-69610
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Programmed Cell Death R-HSA-5357801
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX3 R-HSA-8878159
Interferon alpha/beta signaling R-HSA-909733
Signaling by Hedgehog R-HSA-5358351
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
S Phase R-HSA-69242
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
Signaling by NOTCH4 R-HSA-9013694
TCR signaling R-HSA-202403
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of proteins R-HSA-392499
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI2 by the proteasome R-HSA-5610783
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Vpu mediated degradation of CD4 R-HSA-180534
Axon guidance R-HSA-422475
Interferon Signaling R-HSA-913531
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to hypoxia R-HSA-1234174
Host Interactions of HIV factors R-HSA-162909
Signaling by ROBO receptors R-HSA-376176
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Ub-specific processing proteases R-HSA-5689880
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hedgehog 'off' state R-HSA-5610787
Activation of NF-kappaB in B cells R-HSA-1169091
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by WNT R-HSA-195721
PTEN Regulation R-HSA-6807070
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Apoptosis R-HSA-109581
DNA Replication R-HSA-69306
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX1 R-HSA-8878171
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
PCP/CE pathway R-HSA-4086400

Expression Atlas ENSG00000204264
LRG display in Ensembl gene LRG_1328
NCBI gene (formerly Entrezgene) 5696
GeneCards 9545
HGNC Symbol HGNC:9545
MIM gene 177046
MIM morbid 256040
UniProtKB Gene Name X5D2R7
WikiGene 5696