Gene: PIK3CA
Ensembl ID : ENSG00000121879
Description: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Gene Synonyms: PI3K
36 APIs:
272 Possible Orthologues:

Hemostasis R-HSA-109582
PI3K Cascade R-HSA-109704
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by Insulin receptor R-HSA-74752
IRS-mediated signalling R-HSA-112399
Activated NTRK3 signals through PI3K R-HSA-9603381
RAC1 GTPase cycle R-HSA-9013149
Signaling by NTRK2 (TRKB) R-HSA-9006115
VEGFA-VEGFR2 Pathway R-HSA-4420097
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by ERBB2 in Cancer R-HSA-1227990
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI-3K cascade:FGFR3 R-HSA-5654710
Hemostasis R-HSA-109582
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR2 R-HSA-5654738
Interleukin receptor SHC signaling R-HSA-912526
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by FGFR1 in disease R-HSA-5655302
IGF1R signaling cascade R-HSA-2428924
Interleukin-2 family signaling R-HSA-451927
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by NTRK1 (TRKA) R-HSA-187037
Role of phospholipids in phagocytosis R-HSA-2029485
RET signaling R-HSA-8853659
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
PI-3K cascade:FGFR2 R-HSA-5654695
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by NTRK3 (TRKC) R-HSA-9034015
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
RAF/MAP kinase cascade R-HSA-5673001
Phospholipid metabolism R-HSA-1483257
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by Interleukins R-HSA-449147
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI-3K cascade:FGFR1 R-HSA-5654689
Downstream TCR signaling R-HSA-202424
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by ALK R-HSA-201556
CD28 co-stimulation R-HSA-389356
Disease R-HSA-1643685
Nephrin family interactions R-HSA-373753
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ESR-mediated signaling R-HSA-8939211
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by SCF-KIT R-HSA-1433557
Signaling by ALK in cancer R-HSA-9700206
PI3K Cascade R-HSA-109704
MET activates PI3K/AKT signaling R-HSA-8851907
DAP12 interactions R-HSA-2172127
Regulation of signaling by CBL R-HSA-912631
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by Rho GTPases R-HSA-194315
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
DAP12 signaling R-HSA-2424491
Signaling by MET R-HSA-6806834
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by FGFR R-HSA-190236
RAC2 GTPase cycle R-HSA-9013404
GPVI-mediated activation cascade R-HSA-114604
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by PDGFR in disease R-HSA-9671555
Signaling by EGFR in Cancer R-HSA-1643713
GAB1 signalosome R-HSA-180292
Signaling by NTRKs R-HSA-166520
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR in disease R-HSA-1226099
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
Signaling by FGFR1 R-HSA-5654736
Immune System R-HSA-168256
Signaling by ERBB4 R-HSA-1236394
Downstream signaling of activated FGFR1 R-HSA-5654687
FLT3 signaling in disease R-HSA-9682385
TCR signaling R-HSA-202403
Signaling by FGFR3 R-HSA-5654741
Signaling by Erythropoietin R-HSA-9006335
FLT3 Signaling R-HSA-9607240
Cell-Cell communication R-HSA-1500931
PI3K events in ERBB4 signaling R-HSA-1250342
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Activated NTRK2 signals through PI3K R-HSA-9028335
G alpha (q) signalling events R-HSA-416476
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Extra-nuclear estrogen signaling R-HSA-9009391
Costimulation by the CD28 family R-HSA-388841
Signaling by FGFR2 in disease R-HSA-5655253
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FLT3 fusion proteins R-HSA-9703465
CD28 dependent PI3K/Akt signaling R-HSA-389357
MAPK1/MAPK3 signaling R-HSA-5684996
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Signaling by GPCR R-HSA-372790
Tie2 Signaling R-HSA-210993
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by KIT in disease R-HSA-9669938
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by PDGF R-HSA-186797
Downstream signal transduction R-HSA-186763
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
Signaling by ERBB2 R-HSA-1227986
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by EGFR R-HSA-177929
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
PIP3 activates AKT signaling R-HSA-1257604
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by FGFR4 R-HSA-5654743
Developmental Biology R-HSA-1266738
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
PI3K/AKT activation R-HSA-198203
PI Metabolism R-HSA-1483255
Metabolism of lipids R-HSA-556833
Signaling by VEGF R-HSA-194138
PI-3K cascade:FGFR1 R-HSA-5654689
Adaptive Immune System R-HSA-1280218
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by GPCR R-HSA-372790
Signaling by KIT in disease R-HSA-9669938
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by ALK in cancer R-HSA-9700206
Signaling by Insulin receptor R-HSA-74752
Signaling by PDGFR in disease R-HSA-9671555
CD28 dependent PI3K/Akt signaling R-HSA-389357
PI3K/AKT activation R-HSA-198203
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by NTRK2 (TRKB) R-HSA-9006115
PI3K events in ERBB2 signaling R-HSA-1963642
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by ERBB2 R-HSA-1227986
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by ERBB2 in Cancer R-HSA-1227990
Immune System R-HSA-168256
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Downstream signaling of activated FGFR2 R-HSA-5654696
DAP12 interactions R-HSA-2172127
Signaling by Rho GTPases R-HSA-194315
FLT3 Signaling R-HSA-9607240
Metabolism of lipids R-HSA-556833
Signaling by FGFR4 R-HSA-5654743
GPVI-mediated activation cascade R-HSA-114604
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
DAP12 signaling R-HSA-2424491
FLT3 signaling in disease R-HSA-9682385
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI3K events in ERBB4 signaling R-HSA-1250342
PI Metabolism R-HSA-1483255
Activated NTRK3 signals through PI3K R-HSA-9603381
IGF1R signaling cascade R-HSA-2428924
ESR-mediated signaling R-HSA-8939211
Downstream signaling of activated FGFR3 R-HSA-5654708
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Signaling by PDGF R-HSA-186797
Signaling by FGFR4 in disease R-HSA-5655291
GAB1 signalosome R-HSA-180292
Disease R-HSA-1643685
Regulation of signaling by CBL R-HSA-912631
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Costimulation by the CD28 family R-HSA-388841
Signaling by SCF-KIT R-HSA-1433557
Signaling by FGFR R-HSA-190236
Developmental Biology R-HSA-1266738
Signaling by NTRKs R-HSA-166520
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Intracellular signaling by second messengers R-HSA-9006925
Tie2 Signaling R-HSA-210993
Activated NTRK2 signals through PI3K R-HSA-9028335
RET signaling R-HSA-8853659
Downstream TCR signaling R-HSA-202424
GPCR downstream signalling R-HSA-388396
MAPK1/MAPK3 signaling R-HSA-5684996
Role of phospholipids in phagocytosis R-HSA-2029485
CD28 co-stimulation R-HSA-389356
VEGFA-VEGFR2 Pathway R-HSA-4420097
TCR signaling R-HSA-202403
Interleukin receptor SHC signaling R-HSA-912526
Signaling by EGFRvIII in Cancer R-HSA-5637812
RAC1 GTPase cycle R-HSA-9013149
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by FGFR3 in disease R-HSA-5655332
RHO GTPase cycle R-HSA-9012999
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Nuclear Receptors R-HSA-9006931
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NTRK3 (TRKC) R-HSA-9034015
Innate Immune System R-HSA-168249
Phospholipid metabolism R-HSA-1483257
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by FGFR in disease R-HSA-1226099
Signaling by MET R-HSA-6806834
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by FGFR1 R-HSA-5654736
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Cell-Cell communication R-HSA-1500931
IRS-related events triggered by IGF1R R-HSA-2428928
Nervous system development R-HSA-9675108
Interleukin-2 family signaling R-HSA-451927
Signaling by Interleukins R-HSA-449147
Negative regulation of the PI3K/AKT network R-HSA-199418
Nephrin family interactions R-HSA-373753
Cytokine Signaling in Immune system R-HSA-1280215
Platelet activation, signaling and aggregation R-HSA-76002
IRS-mediated signalling R-HSA-112399
Signal Transduction R-HSA-162582
Signaling by ERBB4 R-HSA-1236394
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Signaling by EGFR R-HSA-177929
PI3K Cascade R-HSA-109704
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by ALK R-HSA-201556
FGFR1 mutant receptor activation R-HSA-1839124
MAPK family signaling cascades R-HSA-5683057
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream signal transduction R-HSA-186763
Constitutive Signaling by EGFRvIII R-HSA-5637810
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by FLT3 fusion proteins R-HSA-9703465
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FGFR2 R-HSA-5654738
Signaling by ERBB2 KD Mutants R-HSA-9664565
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI-3K cascade:FGFR3 R-HSA-5654710
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by FGFR3 R-HSA-5654741
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by VEGF R-HSA-194138
RAC2 GTPase cycle R-HSA-9013404
G alpha (q) signalling events R-HSA-416476
Signaling by Erythropoietin R-HSA-9006335
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by FGFR in disease R-HSA-1226099
Signaling by ALK in cancer R-HSA-9700206
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by FGFR4 in disease R-HSA-5655291
Cell surface interactions at the vascular wall R-HSA-202733
DAP12 signaling R-HSA-2424491
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by ALK R-HSA-201556
Metabolism of lipids R-HSA-556833
MAPK family signaling cascades R-HSA-5683057
PI-3K cascade:FGFR2 R-HSA-5654695
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by ERBB4 R-HSA-1236394
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by FGFR R-HSA-190236
Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
CD28 dependent PI3K/Akt signaling R-HSA-389357
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by GPCR R-HSA-372790
Downstream TCR signaling R-HSA-202424
Signaling by ERBB2 ECD mutants R-HSA-9665348
FLT3 Signaling R-HSA-9607240
Signaling by EGFR R-HSA-177929
PI3K/AKT Signaling in Cancer R-HSA-2219528
Immune System R-HSA-168256
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by PDGF R-HSA-186797
Adaptive Immune System R-HSA-1280218
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by FGFR2 R-HSA-5654738
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
G alpha (q) signalling events R-HSA-416476
Signaling by Rho GTPases R-HSA-194315
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
FLT3 signaling in disease R-HSA-9682385
Interleukin receptor SHC signaling R-HSA-912526
RET signaling R-HSA-8853659
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by FGFR3 in disease R-HSA-5655332
Nervous system development R-HSA-9675108
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by EGFRvIII in Cancer R-HSA-5637812
Constitutive Signaling by EGFRvIII R-HSA-5637810
IGF1R signaling cascade R-HSA-2428924
GAB1 signalosome R-HSA-180292
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RHO GTPase cycle R-HSA-9012999
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by MET R-HSA-6806834
Downstream signal transduction R-HSA-186763
Signaling by NTRK3 (TRKC) R-HSA-9034015
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by VEGF R-HSA-194138
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR1 R-HSA-5654736
Cell-Cell communication R-HSA-1500931
Signaling by FGFR4 R-HSA-5654743
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
Role of phospholipids in phagocytosis R-HSA-2029485
IRS-mediated signalling R-HSA-112399
Signaling by Interleukins R-HSA-449147
Signaling by Erythropoietin R-HSA-9006335
Activated NTRK2 signals through PI3K R-HSA-9028335
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Signaling by KIT in disease R-HSA-9669938
MET activates PI3K/AKT signaling R-HSA-8851907
RAF/MAP kinase cascade R-HSA-5673001
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Axon guidance R-HSA-422475
Hemostasis R-HSA-109582
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by NTRKs R-HSA-166520
Signaling by PDGFR in disease R-HSA-9671555
Intracellular signaling by second messengers R-HSA-9006925
Regulation of signaling by CBL R-HSA-912631
ESR-mediated signaling R-HSA-8939211
Developmental Biology R-HSA-1266738
Signaling by SCF-KIT R-HSA-1433557
GPVI-mediated activation cascade R-HSA-114604
DAP12 interactions R-HSA-2172127
CD28 co-stimulation R-HSA-389356
Costimulation by the CD28 family R-HSA-388841
Platelet activation, signaling and aggregation R-HSA-76002
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RAC2 GTPase cycle R-HSA-9013404
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PI3K/AKT activation R-HSA-198203
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Insulin receptor R-HSA-74752
Nephrin family interactions R-HSA-373753
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Interleukin-2 family signaling R-HSA-451927
Downstream signaling of activated FGFR2 R-HSA-5654696
Activated NTRK3 signals through PI3K R-HSA-9603381
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PI3K Cascade R-HSA-109704
PI3K events in ERBB4 signaling R-HSA-1250342
PI-3K cascade:FGFR3 R-HSA-5654710
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RAC1 GTPase cycle R-HSA-9013149
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 in disease R-HSA-5655253
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by EGFR in Cancer R-HSA-1643713
Insulin receptor signalling cascade R-HSA-74751
Tie2 Signaling R-HSA-210993
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FGFR3 R-HSA-5654741
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Metabolism R-HSA-1430728
PI3K events in ERBB2 signaling R-HSA-1963642
Disease R-HSA-1643685
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by ERBB2 KD Mutants R-HSA-9664565
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR3 R-HSA-5654741
Downstream signal transduction R-HSA-186763
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by FGFR4 in disease R-HSA-5655291
Downstream signaling of activated FGFR1 R-HSA-5654687
FLT3 Signaling R-HSA-9607240
Downstream TCR signaling R-HSA-202424
CD28 dependent PI3K/Akt signaling R-HSA-389357
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Signaling by KIT in disease R-HSA-9669938
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by FGFR1 in disease R-HSA-5655302
Developmental Biology R-HSA-1266738
Signaling by PDGF R-HSA-186797
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Signaling by FGFR3 in disease R-HSA-5655332
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by SCF-KIT R-HSA-1433557
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by FGFR4 R-HSA-5654743
FLT3 signaling in disease R-HSA-9682385
FGFR1 mutant receptor activation R-HSA-1839124
IRS-mediated signalling R-HSA-112399
Axon guidance R-HSA-422475
Downstream signaling of activated FGFR4 R-HSA-5654716
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Tie2 Signaling R-HSA-210993
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Costimulation by the CD28 family R-HSA-388841
Signaling by PDGFR in disease R-HSA-9671555
Role of phospholipids in phagocytosis R-HSA-2029485
Negative regulation of the PI3K/AKT network R-HSA-199418
G alpha (q) signalling events R-HSA-416476
Signaling by FGFR2 in disease R-HSA-5655253
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ALK in cancer R-HSA-9700206
Interleukin-2 family signaling R-HSA-451927
Signaling by EGFR R-HSA-177929
DAP12 interactions R-HSA-2172127
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RAC1 GTPase cycle R-HSA-9013149
PI3K Cascade R-HSA-109704
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by FGFR R-HSA-190236
Nephrin family interactions R-HSA-373753
Interleukin receptor SHC signaling R-HSA-912526
RHO GTPase cycle R-HSA-9012999
Signaling by EGFRvIII in Cancer R-HSA-5637812
TCR signaling R-HSA-202403
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by NTRK3 (TRKC) R-HSA-9034015
RAC2 GTPase cycle R-HSA-9013404
Nervous system development R-HSA-9675108
GPVI-mediated activation cascade R-HSA-114604
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
GPCR downstream signalling R-HSA-388396
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
DAP12 signaling R-HSA-2424491
Signaling by NTRKs R-HSA-166520
Insulin receptor signalling cascade R-HSA-74751
Signaling by GPCR R-HSA-372790
Signaling by ERBB4 R-HSA-1236394
Signaling by ALK R-HSA-201556
Signaling by Interleukins R-HSA-449147
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR in disease R-HSA-1226099
CD28 co-stimulation R-HSA-389356
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by NTRK2 (TRKB) R-HSA-9006115
GAB1 signalosome R-HSA-180292
Signaling by NTRK1 (TRKA) R-HSA-187037
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR1 R-HSA-5654736
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
RET signaling R-HSA-8853659
Downstream signaling of activated FGFR2 R-HSA-5654696
Constitutive Signaling by EGFRvIII R-HSA-5637810
Downstream signaling of activated FGFR3 R-HSA-5654708
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 R-HSA-5654738
Signaling by EGFR in Cancer R-HSA-1643713
PI-3K cascade:FGFR1 R-HSA-5654689
Activated NTRK3 signals through PI3K R-HSA-9603381
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by ERBB2 R-HSA-1227986
Signaling by VEGF R-HSA-194138
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by Erythropoietin R-HSA-9006335
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by MET R-HSA-6806834
PIP3 activates AKT signaling R-HSA-1257604
Cell-Cell communication R-HSA-1500931
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by Rho GTPases R-HSA-194315
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI Metabolism R-HSA-1483255
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ERBB2 ECD mutants R-HSA-9665348
Phospholipid metabolism R-HSA-1483257
PI3K/AKT activation R-HSA-198203
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
PI3K events in ERBB2 signaling R-HSA-1963642
Regulation of signaling by CBL R-HSA-912631
MET activates PI3K/AKT signaling R-HSA-8851907
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by FGFR2 R-HSA-5654738
Signaling by NTRK2 (TRKB) R-HSA-9006115
RAC1 GTPase cycle R-HSA-9013149
DAP12 interactions R-HSA-2172127
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
FGFR1 mutant receptor activation R-HSA-1839124
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Role of phospholipids in phagocytosis R-HSA-2029485
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
RET signaling R-HSA-8853659
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MET activates PI3K/AKT signaling R-HSA-8851907
FLT3 Signaling R-HSA-9607240
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR1 in disease R-HSA-5655302
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by ERBB2 ECD mutants R-HSA-9665348
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Rho GTPases R-HSA-194315
Signaling by FGFR1 R-HSA-5654736
MAPK family signaling cascades R-HSA-5683057
Signaling by ERBB2 in Cancer R-HSA-1227990
Signal Transduction R-HSA-162582
Signaling by Insulin receptor R-HSA-74752
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Interleukin-2 family signaling R-HSA-451927
PI-3K cascade:FGFR1 R-HSA-5654689
GPCR downstream signalling R-HSA-388396
CD28 dependent PI3K/Akt signaling R-HSA-389357
Insulin receptor signalling cascade R-HSA-74751
Platelet activation, signaling and aggregation R-HSA-76002
IGF1R signaling cascade R-HSA-2428924
MAPK1/MAPK3 signaling R-HSA-5684996
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by ERBB2 R-HSA-1227986
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by FGFR3 R-HSA-5654741
Regulation of signaling by CBL R-HSA-912631
Immune System R-HSA-168256
Signaling by NTRK3 (TRKC) R-HSA-9034015
Signaling by ALK in cancer R-HSA-9700206
Signaling by ALK R-HSA-201556
Cell-Cell communication R-HSA-1500931
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K events in ERBB4 signaling R-HSA-1250342
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by PDGFR in disease R-HSA-9671555
Signaling by PDGF R-HSA-186797
Signaling by KIT in disease R-HSA-9669938
Signaling by ERBB2 KD Mutants R-HSA-9664565
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by GPCR R-HSA-372790
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI3K/AKT activation R-HSA-198203
Developmental Biology R-HSA-1266738
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
RAC2 GTPase cycle R-HSA-9013404
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signal transduction R-HSA-186763
Signaling by Interleukins R-HSA-449147
IRS-related events triggered by IGF1R R-HSA-2428928
CD28 co-stimulation R-HSA-389356
Signaling by FGFR2 in disease R-HSA-5655253
Metabolism of lipids R-HSA-556833
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Adaptive Immune System R-HSA-1280218
Signaling by NTRK1 (TRKA) R-HSA-187037
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Axon guidance R-HSA-422475
Signaling by EGFR R-HSA-177929
GPVI-mediated activation cascade R-HSA-114604
FLT3 signaling in disease R-HSA-9682385
Signaling by FGFR4 R-HSA-5654743
Nephrin family interactions R-HSA-373753
Signaling by FGFR3 in disease R-HSA-5655332
Nervous system development R-HSA-9675108
G alpha (q) signalling events R-HSA-416476
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Costimulation by the CD28 family R-HSA-388841
Activated NTRK3 signals through PI3K R-HSA-9603381
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
TCR signaling R-HSA-202403
Downstream signaling of activated FGFR4 R-HSA-5654716
PI Metabolism R-HSA-1483255
Signaling by FGFR R-HSA-190236
PIP3 activates AKT signaling R-HSA-1257604
Signaling by SCF-KIT R-HSA-1433557
GAB1 signalosome R-HSA-180292
IRS-mediated signalling R-HSA-112399
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by VEGF R-HSA-194138
Tie2 Signaling R-HSA-210993
Signaling by MET R-HSA-6806834
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Extra-nuclear estrogen signaling R-HSA-9009391
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Intracellular signaling by second messengers R-HSA-9006925
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by EGFRvIII in Cancer R-HSA-5637812
PI3K Cascade R-HSA-109704
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Phospholipid metabolism R-HSA-1483257
Downstream TCR signaling R-HSA-202424
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by NTRKs R-HSA-166520
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Interleukin receptor SHC signaling R-HSA-912526
DAP12 signaling R-HSA-2424491
Signaling by Erythropoietin R-HSA-9006335
RHO GTPase cycle R-HSA-9012999
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR in disease R-HSA-1226099
Cell surface interactions at the vascular wall R-HSA-202733
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by EGFR R-HSA-177929
Signaling by PDGF R-HSA-186797
Metabolism R-HSA-1430728
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by FGFR1 in disease R-HSA-5655302
PIP3 activates AKT signaling R-HSA-1257604
Activated NTRK3 signals through PI3K R-HSA-9603381
Role of phospholipids in phagocytosis R-HSA-2029485
Adaptive Immune System R-HSA-1280218
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRK1 (TRKA) R-HSA-187037
Signal Transduction R-HSA-162582
PI-3K cascade:FGFR4 R-HSA-5654720
ESR-mediated signaling R-HSA-8939211
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by ALK R-HSA-201556
Cell surface interactions at the vascular wall R-HSA-202733
Costimulation by the CD28 family R-HSA-388841
Signaling by ALK in cancer R-HSA-9700206
Signaling by ERBB2 R-HSA-1227986
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by GPCR R-HSA-372790
DAP12 interactions R-HSA-2172127
Signaling by VEGF R-HSA-194138
Metabolism of lipids R-HSA-556833
Signaling by FGFR1 R-HSA-5654736
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by EGFR in Cancer R-HSA-1643713
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Erythropoietin R-HSA-9006335
Signaling by FGFR in disease R-HSA-1226099
Signaling by FGFR3 R-HSA-5654741
Intracellular signaling by second messengers R-HSA-9006925
PI Metabolism R-HSA-1483255
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
RAF/MAP kinase cascade R-HSA-5673001
IRS-mediated signalling R-HSA-112399
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
FLT3 Signaling R-HSA-9607240
DAP12 signaling R-HSA-2424491
Interleukin receptor SHC signaling R-HSA-912526
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by NTRK3 (TRKC) R-HSA-9034015
FGFR1 mutant receptor activation R-HSA-1839124
Cell-Cell communication R-HSA-1500931
Hemostasis R-HSA-109582
RAC1 GTPase cycle R-HSA-9013149
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by FGFR4 R-HSA-5654743
Developmental Biology R-HSA-1266738
PI3K Cascade R-HSA-109704
PI3K events in ERBB4 signaling R-HSA-1250342
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Cytokine Signaling in Immune system R-HSA-1280215
Nephrin family interactions R-HSA-373753
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FLT3 signaling in disease R-HSA-9682385
IGF1R signaling cascade R-HSA-2428924
Signaling by ERBB4 R-HSA-1236394
Immune System R-HSA-168256
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by NTRK2 (TRKB) R-HSA-9006115
RET signaling R-HSA-8853659
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by FLT3 fusion proteins R-HSA-9703465
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by NTRKs R-HSA-166520
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by SCF-KIT R-HSA-1433557
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by PDGFR in disease R-HSA-9671555
PI-3K cascade:FGFR3 R-HSA-5654710
G alpha (q) signalling events R-HSA-416476
RAC2 GTPase cycle R-HSA-9013404
Signaling by MET R-HSA-6806834
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Rho GTPases R-HSA-194315
GPCR downstream signalling R-HSA-388396
Signaling by FGFR2 R-HSA-5654738
Innate Immune System R-HSA-168249
Interleukin-2 family signaling R-HSA-451927
Downstream signaling of activated FGFR3 R-HSA-5654708
Downstream signaling of activated FGFR1 R-HSA-5654687
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by Insulin receptor R-HSA-74752
RHO GTPase cycle R-HSA-9012999
Signaling by ERBB2 in Cancer R-HSA-1227990
CD28 co-stimulation R-HSA-389356
Activated NTRK2 signals through PI3K R-HSA-9028335
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Interleukins R-HSA-449147
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR3 in disease R-HSA-5655332
Downstream signal transduction R-HSA-186763
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR2 in disease R-HSA-5655253
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by EGFRvIII R-HSA-5637810
Nervous system development R-HSA-9675108
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR R-HSA-190236
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by ERBB2 ECD mutants R-HSA-9665348
Tie2 Signaling R-HSA-210993
Signaling by EGFRvIII in Cancer R-HSA-5637812
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by FGFR4 in disease R-HSA-5655291
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of signaling by CBL R-HSA-912631
Axon guidance R-HSA-422475
Signaling by KIT in disease R-HSA-9669938
Insulin receptor signalling cascade R-HSA-74751
Phospholipid metabolism R-HSA-1483257
Signaling by ERBB2 KD Mutants R-HSA-9664565
PI3K/AKT activation R-HSA-198203
Downstream TCR signaling R-HSA-202424
GAB1 signalosome R-HSA-180292
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Signaling by ALK in cancer R-HSA-9700206
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by ERBB2 ECD mutants R-HSA-9665348
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR1 R-HSA-5654689
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Erythropoietin R-HSA-9006335
G alpha (q) signalling events R-HSA-416476
Signaling by EGFR in Cancer R-HSA-1643713
Downstream signaling of activated FGFR1 R-HSA-5654687
GAB1 signalosome R-HSA-180292
Cell surface interactions at the vascular wall R-HSA-202733
Downstream signaling of activated FGFR2 R-HSA-5654696
PI3K Cascade R-HSA-109704
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream signal transduction R-HSA-186763
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Hemostasis R-HSA-109582
PI-3K cascade:FGFR4 R-HSA-5654720
RHO GTPase cycle R-HSA-9012999
IGF1R signaling cascade R-HSA-2428924
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
DAP12 signaling R-HSA-2424491
RAC1 GTPase cycle R-HSA-9013149
Signaling by SCF-KIT R-HSA-1433557
DAP12 interactions R-HSA-2172127
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR in disease R-HSA-1226099
RAC2 GTPase cycle R-HSA-9013404
Nephrin family interactions R-HSA-373753
Downstream TCR signaling R-HSA-202424
Signaling by ALK R-HSA-201556
Signaling by Interleukins R-HSA-449147
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NTRK3 (TRKC) R-HSA-9034015
Costimulation by the CD28 family R-HSA-388841
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 in disease R-HSA-5655253
Interleukin-2 family signaling R-HSA-451927
Signaling by FGFR4 R-HSA-5654743
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
RET signaling R-HSA-8853659
PI3K events in ERBB2 signaling R-HSA-1963642
Interleukin receptor SHC signaling R-HSA-912526
IRS-related events triggered by IGF1R R-HSA-2428928
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by FGFR R-HSA-190236
Signaling by PDGF R-HSA-186797
Signaling by ERBB2 R-HSA-1227986
PIP3 activates AKT signaling R-HSA-1257604
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by ERBB2 KD Mutants R-HSA-9664565
Adaptive Immune System R-HSA-1280218
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
MET activates PI3K/AKT signaling R-HSA-8851907
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Insulin receptor signalling cascade R-HSA-74751
IRS-mediated signalling R-HSA-112399
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by PDGFR in disease R-HSA-9671555
Axon guidance R-HSA-422475
Activated NTRK2 signals through PI3K R-HSA-9028335
Phospholipid metabolism R-HSA-1483257
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by VEGF R-HSA-194138
Tie2 Signaling R-HSA-210993
Cell-Cell communication R-HSA-1500931
Metabolism of lipids R-HSA-556833
Developmental Biology R-HSA-1266738
Signaling by GPCR R-HSA-372790
PI3K/AKT Signaling in Cancer R-HSA-2219528
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by KIT in disease R-HSA-9669938
GPVI-mediated activation cascade R-HSA-114604
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
FLT3 Signaling R-HSA-9607240
RAF/MAP kinase cascade R-HSA-5673001
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
PI-3K cascade:FGFR2 R-HSA-5654695
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
FLT3 signaling in disease R-HSA-9682385
Signal Transduction R-HSA-162582
Signaling by EGFR R-HSA-177929
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by Nuclear Receptors R-HSA-9006931
TCR signaling R-HSA-202403
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by ERBB4 R-HSA-1236394
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by MET R-HSA-6806834
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI-3K cascade:FGFR3 R-HSA-5654710
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
CD28 co-stimulation R-HSA-389356
Metabolism R-HSA-1430728
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by FGFR2 R-HSA-5654738
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Regulation of signaling by CBL R-HSA-912631
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Rho GTPases R-HSA-194315
Signaling by FGFR1 R-HSA-5654736
ESR-mediated signaling R-HSA-8939211
Signaling by FGFR3 R-HSA-5654741
PI Metabolism R-HSA-1483255
Disease R-HSA-1643685
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by EGFRvIII in Cancer R-HSA-5637812
Activated NTRK3 signals through PI3K R-HSA-9603381
Nervous system development R-HSA-9675108
Signaling by NTRKs R-HSA-166520
PI3K/AKT activation R-HSA-198203
Cytokine Signaling in Immune system R-HSA-1280215
Downstream signaling of activated FGFR4 R-HSA-5654716
Role of phospholipids in phagocytosis R-HSA-2029485
Intracellular signaling by second messengers R-HSA-9006925
Signaling by GPCR R-HSA-372790
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHO GTPase cycle R-HSA-9012999
DAP12 interactions R-HSA-2172127
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI-3K cascade:FGFR3 R-HSA-5654710
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by EGFRvIII in Cancer R-HSA-5637812
Downstream signaling of activated FGFR4 R-HSA-5654716
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Insulin receptor R-HSA-74752
Signaling by EGFR R-HSA-177929
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK in cancer R-HSA-9700206
PI3K/AKT Signaling in Cancer R-HSA-2219528
GPCR downstream signalling R-HSA-388396
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 family signaling R-HSA-451927
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by ERBB2 KD Mutants R-HSA-9664565
Hemostasis R-HSA-109582
RAC2 GTPase cycle R-HSA-9013404
Disease R-HSA-1643685
CD28 dependent PI3K/Akt signaling R-HSA-389357
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI3K Cascade R-HSA-109704
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by FGFR2 R-HSA-5654738
Interleukin receptor SHC signaling R-HSA-912526
Signaling by VEGF R-HSA-194138
IRS-mediated signalling R-HSA-112399
RAF/MAP kinase cascade R-HSA-5673001
TCR signaling R-HSA-202403
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by Interleukins R-HSA-449147
Signaling by FGFR1 in disease R-HSA-5655302
Metabolism of lipids R-HSA-556833
Nervous system development R-HSA-9675108
RET signaling R-HSA-8853659
FLT3 Signaling R-HSA-9607240
Signaling by NTRK3 (TRKC) R-HSA-9034015
Nephrin family interactions R-HSA-373753
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by FGFR4 R-HSA-5654743
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by FGFR R-HSA-190236
Signaling by Erythropoietin R-HSA-9006335
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR3 R-HSA-5654741
Downstream signaling of activated FGFR1 R-HSA-5654687
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NTRKs R-HSA-166520
G alpha (q) signalling events R-HSA-416476
PI-3K cascade:FGFR4 R-HSA-5654720
PI3K/AKT activation R-HSA-198203
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of signaling by CBL R-HSA-912631
Signaling by PDGF R-HSA-186797
Platelet activation, signaling and aggregation R-HSA-76002
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by FGFR1 R-HSA-5654736
Signaling by KIT in disease R-HSA-9669938
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by FGFR in disease R-HSA-1226099
FLT3 signaling in disease R-HSA-9682385
DAP12 signaling R-HSA-2424491
Signaling by ERBB4 R-HSA-1236394
Signaling by Rho GTPases R-HSA-194315
Signaling by ERBB2 ECD mutants R-HSA-9665348
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Costimulation by the CD28 family R-HSA-388841
ESR-mediated signaling R-HSA-8939211
PI-3K cascade:FGFR2 R-HSA-5654695
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
Signaling by NTRK2 (TRKB) R-HSA-9006115
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by EGFR in Cancer R-HSA-1643713
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
IGF1R signaling cascade R-HSA-2428924
Activated NTRK3 signals through PI3K R-HSA-9603381
Signal Transduction R-HSA-162582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Tie2 Signaling R-HSA-210993
Adaptive Immune System R-HSA-1280218
Signaling by FGFR4 in disease R-HSA-5655291
PI-3K cascade:FGFR1 R-HSA-5654689
Metabolism R-HSA-1430728
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
PI Metabolism R-HSA-1483255
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Axon guidance R-HSA-422475
Cell-Cell communication R-HSA-1500931
Signaling by NTRK1 (TRKA) R-HSA-187037
Innate Immune System R-HSA-168249
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by ERBB2 in Cancer R-HSA-1227990
Downstream signal transduction R-HSA-186763
GAB1 signalosome R-HSA-180292
Constitutive Signaling by EGFRvIII R-HSA-5637810
Insulin receptor signalling cascade R-HSA-74751
Signaling by FLT3 fusion proteins R-HSA-9703465
PI3K events in ERBB2 signaling R-HSA-1963642
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by MET R-HSA-6806834
Phospholipid metabolism R-HSA-1483257
Signaling by ALK R-HSA-201556
Signaling by PDGFR in disease R-HSA-9671555
Signaling by ERBB2 R-HSA-1227986
CD28 co-stimulation R-HSA-389356
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Cell surface interactions at the vascular wall R-HSA-202733
GPVI-mediated activation cascade R-HSA-114604
Signaling by SCF-KIT R-HSA-1433557
RAC1 GTPase cycle R-HSA-9013149
Signaling by FGFR3 in disease R-HSA-5655332
Negative regulation of the PI3K/AKT network R-HSA-199418
Nephrin family interactions R-HSA-373753
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ALK R-HSA-201556
Signaling by FGFR2 in disease R-HSA-5655253
Innate Immune System R-HSA-168249
MET activates PI3K/AKT signaling R-HSA-8851907
RAC1 GTPase cycle R-HSA-9013149
Downstream signaling of activated FGFR4 R-HSA-5654716
FLT3 Signaling R-HSA-9607240
PI-3K cascade:FGFR2 R-HSA-5654695
IRS-related events triggered by IGF1R R-HSA-2428928
Interleukin-2 family signaling R-HSA-451927
Signaling by NTRKs R-HSA-166520
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by FLT3 fusion proteins R-HSA-9703465
Metabolism R-HSA-1430728
Phospholipid metabolism R-HSA-1483257
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ERBB4 R-HSA-1236394
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by KIT in disease R-HSA-9669938
TCR signaling R-HSA-202403
Signaling by ERBB2 KD Mutants R-HSA-9664565
Tie2 Signaling R-HSA-210993
GPVI-mediated activation cascade R-HSA-114604
PI-3K cascade:FGFR4 R-HSA-5654720
Intracellular signaling by second messengers R-HSA-9006925
Developmental Biology R-HSA-1266738
GPCR downstream signalling R-HSA-388396
Costimulation by the CD28 family R-HSA-388841
RET signaling R-HSA-8853659
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Downstream signaling of activated FGFR1 R-HSA-5654687
Role of phospholipids in phagocytosis R-HSA-2029485
G alpha (q) signalling events R-HSA-416476
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
GAB1 signalosome R-HSA-180292
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Downstream TCR signaling R-HSA-202424
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR3 R-HSA-5654741
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Downstream signal transduction R-HSA-186763
PI Metabolism R-HSA-1483255
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by PDGF R-HSA-186797
PI3K events in ERBB2 signaling R-HSA-1963642
RHO GTPase cycle R-HSA-9012999
Regulation of signaling by CBL R-HSA-912631
Signaling by FGFR in disease R-HSA-1226099
Signaling by PDGFR in disease R-HSA-9671555
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
Cell-Cell communication R-HSA-1500931
ESR-mediated signaling R-HSA-8939211
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by ERBB2 R-HSA-1227986
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Activated NTRK2 signals through PI3K R-HSA-9028335
Interleukin receptor SHC signaling R-HSA-912526
Signaling by MET R-HSA-6806834
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
PI3K/AKT Signaling in Cancer R-HSA-2219528
Synthesis of PIPs at the plasma membrane R-HSA-1660499
FLT3 signaling in disease R-HSA-9682385
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by EGFR R-HSA-177929
Signaling by FGFR1 R-HSA-5654736
Cytokine Signaling in Immune system R-HSA-1280215
Cell surface interactions at the vascular wall R-HSA-202733
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Interleukins R-HSA-449147
Signaling by ERBB2 in Cancer R-HSA-1227990
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DAP12 signaling R-HSA-2424491
Signaling by NTRK2 (TRKB) R-HSA-9006115
MAPK1/MAPK3 signaling R-HSA-5684996
Insulin receptor signalling cascade R-HSA-74751
Signaling by Insulin receptor R-HSA-74752
Signaling by ERBB2 ECD mutants R-HSA-9665348
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Signaling by FGFR2 R-HSA-5654738
RAC2 GTPase cycle R-HSA-9013404
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Rho GTPases R-HSA-194315
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of lipids R-HSA-556833
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT activation R-HSA-198203
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by FGFR4 R-HSA-5654743
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
IRS-mediated signalling R-HSA-112399
PI3K events in ERBB4 signaling R-HSA-1250342
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Erythropoietin R-HSA-9006335
Signaling by FGFR R-HSA-190236
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by EGFRvIII in Cancer R-HSA-5637812
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by NTRK3 (TRKC) R-HSA-9034015
PI3K Cascade R-HSA-109704
Signaling by ALK in cancer R-HSA-9700206
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Platelet activation, signaling and aggregation R-HSA-76002
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR3 R-HSA-5654710
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PIP3 activates AKT signaling R-HSA-1257604
DAP12 interactions R-HSA-2172127
Axon guidance R-HSA-422475
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by SCF-KIT R-HSA-1433557
CD28 co-stimulation R-HSA-389356
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Downstream signaling of activated FGFR3 R-HSA-5654708
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by FGFR in disease R-HSA-1226099
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by NTRK3 (TRKC) R-HSA-9034015
PI-3K cascade:FGFR1 R-HSA-5654689
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by GPCR R-HSA-372790
Interleukin receptor SHC signaling R-HSA-912526
Signaling by FGFR3 in disease R-HSA-5655332
FGFR1 mutant receptor activation R-HSA-1839124
ESR-mediated signaling R-HSA-8939211
Signaling by Interleukins R-HSA-449147
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Insulin receptor signalling cascade R-HSA-74751
Phospholipid metabolism R-HSA-1483257
Signaling by Insulin receptor R-HSA-74752
RHO GTPase cycle R-HSA-9012999
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MAPK family signaling cascades R-HSA-5683057
Signaling by KIT in disease R-HSA-9669938
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
DAP12 interactions R-HSA-2172127
FLT3 Signaling R-HSA-9607240
IGF1R signaling cascade R-HSA-2428924
Signaling by ALK in cancer R-HSA-9700206
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by EGFR R-HSA-177929
Regulation of signaling by CBL R-HSA-912631
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Adaptive Immune System R-HSA-1280218
Interleukin-2 family signaling R-HSA-451927
Signaling by Erythropoietin R-HSA-9006335
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by NTRKs R-HSA-166520
G alpha (q) signalling events R-HSA-416476
Extra-nuclear estrogen signaling R-HSA-9009391
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Costimulation by the CD28 family R-HSA-388841
Signaling by ERBB2 in Cancer R-HSA-1227990
DAP12 signaling R-HSA-2424491
Signaling by SCF-KIT R-HSA-1433557
Axon guidance R-HSA-422475
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of lipids R-HSA-556833
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by EGFR in Cancer R-HSA-1643713
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by FGFR2 R-HSA-5654738
Tie2 Signaling R-HSA-210993
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by EGFRvIII in Cancer R-HSA-5637812
Activated NTRK2 signals through PI3K R-HSA-9028335
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Activated NTRK3 signals through PI3K R-HSA-9603381
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by NTRK2 (TRKB) R-HSA-9006115
CD28 co-stimulation R-HSA-389356
GPCR downstream signalling R-HSA-388396
Nephrin family interactions R-HSA-373753
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by ERBB2 R-HSA-1227986
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by FGFR R-HSA-190236
GAB1 signalosome R-HSA-180292
PI-3K cascade:FGFR2 R-HSA-5654695
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Immune System R-HSA-168256
PI-3K cascade:FGFR4 R-HSA-5654720
Metabolism R-HSA-1430728
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by PDGFR in disease R-HSA-9671555
Hemostasis R-HSA-109582
Signaling by VEGF R-HSA-194138
RET signaling R-HSA-8853659
Signaling by FGFR2 in disease R-HSA-5655253
PI Metabolism R-HSA-1483255
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PIP3 activates AKT signaling R-HSA-1257604
GPVI-mediated activation cascade R-HSA-114604
Signaling by FGFR3 R-HSA-5654741
Signaling by PDGF R-HSA-186797
VEGFA-VEGFR2 Pathway R-HSA-4420097
PI-3K cascade:FGFR3 R-HSA-5654710
CD28 dependent PI3K/Akt signaling R-HSA-389357
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RAC2 GTPase cycle R-HSA-9013404
Signaling by FGFR1 R-HSA-5654736
FLT3 signaling in disease R-HSA-9682385
Signaling by ERBB4 R-HSA-1236394
RAC1 GTPase cycle R-HSA-9013149
PI3K/AKT activation R-HSA-198203
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by ERBB2 ECD mutants R-HSA-9665348
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Rho GTPases R-HSA-194315
TCR signaling R-HSA-202403
Cell-Cell communication R-HSA-1500931
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by MET R-HSA-6806834
Signaling by NTRK1 (TRKA) R-HSA-187037
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ALK R-HSA-201556
Signaling by FGFR4 R-HSA-5654743
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Downstream signal transduction R-HSA-186763
IRS-mediated signalling R-HSA-112399
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Downstream signaling of activated FGFR3 R-HSA-5654708
Nervous system development R-HSA-9675108

Expression Atlas ENSG00000121879
LRG display in Ensembl gene LRG_310
NCBI gene (formerly Entrezgene) 5290
GeneCards 8975
HGNC Symbol HGNC:8975
MIM gene 171834
MIM morbid 619538
UniProtKB Gene Name P42336
WikiGene 5290
Gene: PARP1
Ensembl ID : ENSG00000143799
Description: poly(ADP-ribose) polymerase 1
Gene Synonyms: ADPRT,ARTD1,PARP,PARS,POLY-PARP,PPOL
10 APIs:
206 Possible Orthologues:

SUMOylation of DNA damage response and repair proteins R-HSA-3108214
DNA Damage Recognition in GG-NER R-HSA-5696394
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
vRNA Synthesis R-HSA-192814
Gene expression (Transcription) R-HSA-74160
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Signaling by TGFB family members R-HSA-9006936
Nucleotide Excision Repair R-HSA-5696398
Influenza Infection R-HSA-168255
Formation of Incision Complex in GG-NER R-HSA-5696395
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Metabolism of proteins R-HSA-392499
Homology Directed Repair R-HSA-5693538
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Dual Incision in GG-NER R-HSA-5696400
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Influenza Viral RNA Transcription and Replication R-HSA-168273
SUMOylation R-HSA-2990846
DNA Repair R-HSA-73894
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Resolution of Abasic Sites (AP sites) R-HSA-73933
Signaling by TGF-beta Receptor Complex R-HSA-170834
Generic Transcription Pathway R-HSA-212436
Base Excision Repair R-HSA-73884
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Base Excision Repair R-HSA-73884
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Dual Incision in GG-NER R-HSA-5696400
Disease R-HSA-1643685
DNA Double-Strand Break Repair R-HSA-5693532
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Signaling by TGF-beta Receptor Complex R-HSA-170834
DNA Repair R-HSA-73894
Formation of Incision Complex in GG-NER R-HSA-5696395
Homology Directed Repair R-HSA-5693538
Resolution of Abasic Sites (AP sites) R-HSA-73933
RNA Polymerase II Transcription R-HSA-73857
vRNA Synthesis R-HSA-192814
DNA Damage Recognition in GG-NER R-HSA-5696394
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signaling by TGFB family members R-HSA-9006936
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Influenza Viral RNA Transcription and Replication R-HSA-168273
Nucleotide Excision Repair R-HSA-5696398
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Metabolism of proteins R-HSA-392499
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Influenza Infection R-HSA-168255
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
SUMOylation R-HSA-2990846
SUMOylation R-HSA-2990846
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Signal Transduction R-HSA-162582
Resolution of Abasic Sites (AP sites) R-HSA-73933
Infectious disease R-HSA-5663205
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by TGF-beta Receptor Complex R-HSA-170834
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
DNA Damage Recognition in GG-NER R-HSA-5696394
RNA Polymerase II Transcription R-HSA-73857
Signaling by TGFB family members R-HSA-9006936
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Base Excision Repair R-HSA-73884
Dual Incision in GG-NER R-HSA-5696400
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Formation of Incision Complex in GG-NER R-HSA-5696395
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Nucleotide Excision Repair R-HSA-5696398
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Influenza Viral RNA Transcription and Replication R-HSA-168273
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
vRNA Synthesis R-HSA-192814
Homology Directed Repair R-HSA-5693538
Influenza Infection R-HSA-168255
DNA Damage Recognition in GG-NER R-HSA-5696394
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Generic Transcription Pathway R-HSA-212436
Base Excision Repair R-HSA-73884
Resolution of Abasic Sites (AP sites) R-HSA-73933
RNA Polymerase II Transcription R-HSA-73857
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Signaling by TGFB family members R-HSA-9006936
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
Nucleotide Excision Repair R-HSA-5696398
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Signaling by TGF-beta Receptor Complex R-HSA-170834
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
SUMOylation R-HSA-2990846
DNA Double-Strand Break Repair R-HSA-5693532
Homology Directed Repair R-HSA-5693538
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Influenza Viral RNA Transcription and Replication R-HSA-168273
Gene expression (Transcription) R-HSA-74160
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Dual Incision in GG-NER R-HSA-5696400
vRNA Synthesis R-HSA-192814
Influenza Infection R-HSA-168255
Formation of Incision Complex in GG-NER R-HSA-5696395
DNA Repair R-HSA-73894
vRNA Synthesis R-HSA-192814
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Base Excision Repair R-HSA-73884
Resolution of Abasic Sites (AP sites) R-HSA-73933
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
DNA Damage Recognition in GG-NER R-HSA-5696394
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Gene expression (Transcription) R-HSA-74160
Influenza Infection R-HSA-168255
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Homology Directed Repair R-HSA-5693538
DNA Double-Strand Break Repair R-HSA-5693532
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Influenza Viral RNA Transcription and Replication R-HSA-168273
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
Nucleotide Excision Repair R-HSA-5696398
Formation of Incision Complex in GG-NER R-HSA-5696395
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by TGFB family members R-HSA-9006936
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Post-translational protein modification R-HSA-597592
DNA Repair R-HSA-73894
Dual Incision in GG-NER R-HSA-5696400
DNA Double-Strand Break Repair R-HSA-5693532
vRNA Synthesis R-HSA-192814
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Metabolism of proteins R-HSA-392499
Influenza Viral RNA Transcription and Replication R-HSA-168273
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Formation of Incision Complex in GG-NER R-HSA-5696395
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Homology Directed Repair R-HSA-5693538
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Influenza Infection R-HSA-168255
Dual Incision in GG-NER R-HSA-5696400
Nucleotide Excision Repair R-HSA-5696398
DNA Damage Recognition in GG-NER R-HSA-5696394
Generic Transcription Pathway R-HSA-212436
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
RNA Polymerase II Transcription R-HSA-73857
DNA Repair R-HSA-73894
Base Excision Repair R-HSA-73884
Resolution of Abasic Sites (AP sites) R-HSA-73933
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
Disease R-HSA-1643685
Signaling by TGF-beta Receptor Complex R-HSA-170834
SUMOylation R-HSA-2990846
Nucleotide Excision Repair R-HSA-5696398
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Signaling by TGF-beta Receptor Complex R-HSA-170834
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Base Excision Repair R-HSA-73884
Formation of Incision Complex in GG-NER R-HSA-5696395
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
DNA Damage Recognition in GG-NER R-HSA-5696394
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Dual Incision in GG-NER R-HSA-5696400
Homology Directed Repair R-HSA-5693538
Influenza Infection R-HSA-168255
vRNA Synthesis R-HSA-192814
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
RNA Polymerase II Transcription R-HSA-73857
Resolution of Abasic Sites (AP sites) R-HSA-73933
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Generic Transcription Pathway R-HSA-212436
Signaling by TGFB family members R-HSA-9006936
Influenza Viral RNA Transcription and Replication R-HSA-168273
Metabolism of proteins R-HSA-392499
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
DNA Damage Recognition in GG-NER R-HSA-5696394
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Dual Incision in GG-NER R-HSA-5696400
DNA Double-Strand Break Repair R-HSA-5693532
vRNA Synthesis R-HSA-192814
Resolution of Abasic Sites (AP sites) R-HSA-73933
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Influenza Infection R-HSA-168255
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Generic Transcription Pathway R-HSA-212436
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Base Excision Repair R-HSA-73884
Signaling by TGFB family members R-HSA-9006936
Formation of Incision Complex in GG-NER R-HSA-5696395
Signal Transduction R-HSA-162582
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Nucleotide Excision Repair R-HSA-5696398
Signaling by TGF-beta Receptor Complex R-HSA-170834
Homology Directed Repair R-HSA-5693538
Disease R-HSA-1643685
Influenza Viral RNA Transcription and Replication R-HSA-168273
Gene expression (Transcription) R-HSA-74160
DNA Repair R-HSA-73894
SUMOylation R-HSA-2990846
SUMOylation R-HSA-2990846
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
Base Excision Repair R-HSA-73884
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Post-translational protein modification R-HSA-597592
vRNA Synthesis R-HSA-192814
Homology Directed Repair R-HSA-5693538
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Gene expression (Transcription) R-HSA-74160
Dual Incision in GG-NER R-HSA-5696400
Resolution of Abasic Sites (AP sites) R-HSA-73933
Nucleotide Excision Repair R-HSA-5696398
Signaling by TGF-beta Receptor Complex R-HSA-170834
Influenza Infection R-HSA-168255
DNA Double-Strand Break Repair R-HSA-5693532
Signal Transduction R-HSA-162582
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Signaling by TGFB family members R-HSA-9006936
Metabolism of proteins R-HSA-392499
DNA Damage Recognition in GG-NER R-HSA-5696394
Formation of Incision Complex in GG-NER R-HSA-5696395
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Disease R-HSA-1643685
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Repair R-HSA-73894
Influenza Viral RNA Transcription and Replication R-HSA-168273
Signal Transduction R-HSA-162582
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Base Excision Repair R-HSA-73884
Influenza Infection R-HSA-168255
Signaling by TGF-beta Receptor Complex R-HSA-170834
RNA Polymerase II Transcription R-HSA-73857
Resolution of Abasic Sites (AP sites) R-HSA-73933
Influenza Viral RNA Transcription and Replication R-HSA-168273
DNA Damage Recognition in GG-NER R-HSA-5696394
Signaling by TGFB family members R-HSA-9006936
Disease R-HSA-1643685
Homology Directed Repair R-HSA-5693538
DNA Double-Strand Break Repair R-HSA-5693532
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
Nucleotide Excision Repair R-HSA-5696398
Generic Transcription Pathway R-HSA-212436
DNA Repair R-HSA-73894
Dual Incision in GG-NER R-HSA-5696400
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
vRNA Synthesis R-HSA-192814
Formation of Incision Complex in GG-NER R-HSA-5696395
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Infectious disease R-HSA-5663205
SUMOylation R-HSA-2990846
Base Excision Repair R-HSA-73884
Dual Incision in GG-NER R-HSA-5696400
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Formation of Incision Complex in GG-NER R-HSA-5696395
Homology Directed Repair R-HSA-5693538
Signal Transduction R-HSA-162582
Resolution of Abasic Sites (AP sites) R-HSA-73933
Gene expression (Transcription) R-HSA-74160
Influenza Viral RNA Transcription and Replication R-HSA-168273
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
DNA Repair R-HSA-73894
Signaling by TGFB family members R-HSA-9006936
Influenza Infection R-HSA-168255
RNA Polymerase II Transcription R-HSA-73857
vRNA Synthesis R-HSA-192814
Signaling by TGF-beta Receptor Complex R-HSA-170834
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
DNA Double-Strand Break Repair R-HSA-5693532
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
SUMOylation of DNA damage response and repair proteins R-HSA-3108214
DNA Damage Recognition in GG-NER R-HSA-5696394
Generic Transcription Pathway R-HSA-212436
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Nucleotide Excision Repair R-HSA-5696398

Expression Atlas ENSG00000143799
NCBI gene (formerly Entrezgene) 142
GeneCards 270
HGNC Symbol HGNC:270
MIM gene 173870
UniProtKB Gene Name P09874
WikiGene 142
Gene: MMP2
Ensembl ID : ENSG00000087245
Description: matrix metallopeptidase 2
Gene Synonyms: CLG4,CLG4A,TBE-1
1 APIs:
210 Possible Orthologues:

Extracellular matrix organization R-HSA-1474244
EPH-Ephrin signaling R-HSA-2682334
Degradation of the extracellular matrix R-HSA-1474228
Axon guidance R-HSA-422475
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Metabolism of proteins R-HSA-392499
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
Nervous system development R-HSA-9675108
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
Collagen degradation R-HSA-1442490
Extra-nuclear estrogen signaling R-HSA-9009391
MAPK6/MAPK4 signaling R-HSA-5687128
Collagen degradation R-HSA-1442490
Activation of Matrix Metalloproteinases R-HSA-1592389
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Nuclear Receptors R-HSA-9006931
Extracellular matrix organization R-HSA-1474244
EPH-Ephrin signaling R-HSA-2682334
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Cytokine Signaling in Immune system R-HSA-1280215
EPH-Ephrin signaling R-HSA-2682334
ESR-mediated signaling R-HSA-8939211
Nervous system development R-HSA-9675108
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Collagen degradation R-HSA-1442490
MAPK family signaling cascades R-HSA-5683057
Immune System R-HSA-168256
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Extracellular matrix organization R-HSA-1474244
Extra-nuclear estrogen signaling R-HSA-9009391
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by Nuclear Receptors R-HSA-9006931
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Axon guidance R-HSA-422475
Extracellular matrix organization R-HSA-1474244
MAPK family signaling cascades R-HSA-5683057
Metabolism of proteins R-HSA-392499
EPH-Ephrin signaling R-HSA-2682334
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Collagen degradation R-HSA-1442490
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Nuclear Receptors R-HSA-9006931
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Extracellular matrix organization R-HSA-1474244
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
EPH-ephrin mediated repulsion of cells R-HSA-3928665
ESR-mediated signaling R-HSA-8939211
EPH-Ephrin signaling R-HSA-2682334
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Extra-nuclear estrogen signaling R-HSA-9009391
Developmental Biology R-HSA-1266738
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Nervous system development R-HSA-9675108
Signaling by Nuclear Receptors R-HSA-9006931
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Extra-nuclear estrogen signaling R-HSA-9009391
Cytokine Signaling in Immune system R-HSA-1280215
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
Extracellular matrix organization R-HSA-1474244
Collagen degradation R-HSA-1442490
EPH-Ephrin signaling R-HSA-2682334
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
MAPK family signaling cascades R-HSA-5683057
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
EPH-ephrin mediated repulsion of cells R-HSA-3928665
MAPK family signaling cascades R-HSA-5683057
Extracellular matrix organization R-HSA-1474244
Signaling by Interleukins R-HSA-449147
ESR-mediated signaling R-HSA-8939211
Signaling by Nuclear Receptors R-HSA-9006931
Nervous system development R-HSA-9675108
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Metabolism of proteins R-HSA-392499
Degradation of the extracellular matrix R-HSA-1474228
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
Collagen degradation R-HSA-1442490
Developmental Biology R-HSA-1266738
Activation of Matrix Metalloproteinases R-HSA-1592389
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Extra-nuclear estrogen signaling R-HSA-9009391
MAPK6/MAPK4 signaling R-HSA-5687128
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by Interleukins R-HSA-449147
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Activation of Matrix Metalloproteinases R-HSA-1592389
Extra-nuclear estrogen signaling R-HSA-9009391
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
ESR-mediated signaling R-HSA-8939211
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Developmental Biology R-HSA-1266738
Signaling by Nuclear Receptors R-HSA-9006931
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
MAPK family signaling cascades R-HSA-5683057
EPH-ephrin mediated repulsion of cells R-HSA-3928665
EPH-Ephrin signaling R-HSA-2682334
Signaling by Nuclear Receptors R-HSA-9006931
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Interleukins R-HSA-449147
Extracellular matrix organization R-HSA-1474244
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of proteins R-HSA-392499
Collagen degradation R-HSA-1442490
ESR-mediated signaling R-HSA-8939211
Axon guidance R-HSA-422475
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Cytokine Signaling in Immune system R-HSA-1280215
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Extracellular matrix organization R-HSA-1474244
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Nuclear Receptors R-HSA-9006931
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
Activation of Matrix Metalloproteinases R-HSA-1592389
Axon guidance R-HSA-422475
Metabolism of proteins R-HSA-392499
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
EPH-Ephrin signaling R-HSA-2682334
ESR-mediated signaling R-HSA-8939211

Expression Atlas ENSG00000087245
NCBI gene (formerly Entrezgene) 4313
GeneCards 7166
HGNC Symbol HGNC:7166
MIM gene 120360
MIM morbid 259600
UniProtKB Gene Name P08253
WikiGene 4313
Gene: PDE7A
Ensembl ID : ENSG00000205268
Description: phosphodiesterase 7A
Gene Synonyms: HCP1
1 APIs:
240 Possible Orthologues:

GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (s) signalling events R-HSA-418555
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555
G alpha (s) signalling events R-HSA-418555
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
G alpha (s) signalling events R-HSA-418555

Expression Atlas ENSG00000205268
NCBI gene (formerly Entrezgene) 5150
GeneCards 8791
HGNC Symbol HGNC:8791
MIM gene 171885
UniProtKB Gene Name Q13946
WikiGene 5150
Gene: PLG
Ensembl ID : ENSG00000122194
Description: plasminogen
Gene Synonyms:
12 APIs:
263 Possible Orthologues:

Signaling by PDGF R-HSA-186797
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Platelet degranulation R-HSA-114608
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Degradation of the extracellular matrix R-HSA-1474228
Dissolution of Fibrin Clot R-HSA-75205
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by PDGF R-HSA-186797
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Extracellular matrix organization R-HSA-1474244
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Platelet degranulation R-HSA-114608
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of proteins R-HSA-392499
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Dissolution of Fibrin Clot R-HSA-75205
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Platelet degranulation R-HSA-114608
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Activation of Matrix Metalloproteinases R-HSA-1592389
Dissolution of Fibrin Clot R-HSA-75205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Extracellular matrix organization R-HSA-1474244
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Activation of Matrix Metalloproteinases R-HSA-1592389
Platelet degranulation R-HSA-114608
Extracellular matrix organization R-HSA-1474244
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Dissolution of Fibrin Clot R-HSA-75205
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Degradation of the extracellular matrix R-HSA-1474228
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by PDGF R-HSA-186797
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Activation of Matrix Metalloproteinases R-HSA-1592389
Hemostasis R-HSA-109582
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Dissolution of Fibrin Clot R-HSA-75205
Metabolism of proteins R-HSA-392499
Platelet degranulation R-HSA-114608
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet activation, signaling and aggregation R-HSA-76002
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Extracellular matrix organization R-HSA-1474244
Signaling by PDGF R-HSA-186797
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Degradation of the extracellular matrix R-HSA-1474228
Hemostasis R-HSA-109582
Platelet degranulation R-HSA-114608
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by PDGF R-HSA-186797
Platelet activation, signaling and aggregation R-HSA-76002
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Dissolution of Fibrin Clot R-HSA-75205
Platelet degranulation R-HSA-114608
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Degradation of the extracellular matrix R-HSA-1474228
Platelet degranulation R-HSA-114608
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Dissolution of Fibrin Clot R-HSA-75205
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Platelet degranulation R-HSA-114608
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Hemostasis R-HSA-109582
Dissolution of Fibrin Clot R-HSA-75205
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Metabolism of proteins R-HSA-392499

Expression Atlas ENSG00000122194
LRG display in Ensembl gene LRG_571
NCBI gene (formerly Entrezgene) 5340
GeneCards 9071
HGNC Symbol HGNC:9071
MIM gene 173350
MIM morbid 619360
UniProtKB Gene Name Q5TEH5
WikiGene 5340
Gene: PSMA7
Ensembl ID : ENSG00000101182
Description: proteasome 20S subunit alpha 7
Gene Synonyms: C6,HSPC,RC6-1,XAPC7
6 APIs:
153 Possible Orthologues:

Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Anaphase R-HSA-68882
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by Interleukins R-HSA-449147
Assembly of the pre-replicative complex R-HSA-68867
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of Apoptosis R-HSA-169911
Cell Cycle R-HSA-1640170
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Cell Cycle, Mitotic R-HSA-69278
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Metabolism R-HSA-1430728
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
Beta-catenin independent WNT signaling R-HSA-3858494
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants abrogate ligand secretion R-HSA-5387390
Developmental Biology R-HSA-1266738
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
p53-Independent DNA Damage Response R-HSA-69610
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
S Phase R-HSA-69242
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stress R-HSA-2262752
Ub-specific processing proteases R-HSA-5689880
Immune System R-HSA-168256
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
M Phase R-HSA-68886
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cyclin E associated events during G1/S transition R-HSA-69202
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Dependent G1 DNA Damage Response R-HSA-69563
Downstream TCR signaling R-HSA-202424
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RAS by GAPs R-HSA-5658442
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Separation of Sister Chromatids R-HSA-2467813
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of AXIN R-HSA-4641257
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
Activation of NF-kappaB in B cells R-HSA-1169091
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Class I MHC mediated antigen processing & presentation R-HSA-983169
TCF dependent signaling in response to WNT R-HSA-201681
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PCP/CE pathway R-HSA-4086400
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Hedgehog R-HSA-5358351
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
UCH proteinases R-HSA-5689603
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mitotic cell cycle R-HSA-453276
ABC-family proteins mediated transport R-HSA-382556
ER-Phagosome pathway R-HSA-1236974
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing-Cross presentation R-HSA-1236975
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of proteins R-HSA-392499
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
RAF/MAP kinase cascade R-HSA-5673001
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
KEAP1-NFE2L2 pathway R-HSA-9755511
Vif-mediated degradation of APOBEC3G R-HSA-180585
ER-Phagosome pathway R-HSA-1236974
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Signaling by WNT R-HSA-195721
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Separation of Sister Chromatids R-HSA-2467813
Post-translational protein modification R-HSA-597592
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
UCH proteinases R-HSA-5689603
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Assembly of the pre-replicative complex R-HSA-68867
PCP/CE pathway R-HSA-4086400
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
DNA Replication Pre-Initiation R-HSA-69002
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
MAPK1/MAPK3 signaling R-HSA-5684996
ABC-family proteins mediated transport R-HSA-382556
Hedgehog 'off' state R-HSA-5610787
Gene expression (Transcription) R-HSA-74160
G2/M Checkpoints R-HSA-69481
Cellular response to chemical stress R-HSA-9711123
FCERI mediated NF-kB activation R-HSA-2871837
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Programmed Cell Death R-HSA-5357801
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Intracellular signaling by second messengers R-HSA-9006925
Stabilization of p53 R-HSA-69541
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of PTEN stability and activity R-HSA-8948751
S Phase R-HSA-69242
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Regulation of RAS by GAPs R-HSA-5658442
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mitotic cell cycle R-HSA-453276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
Switching of origins to a post-replicative state R-HSA-69052
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Interleukins R-HSA-449147
PIP3 activates AKT signaling R-HSA-1257604
G2/M Transition R-HSA-69275
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
Defective CFTR causes cystic fibrosis R-HSA-5678895
M Phase R-HSA-68886
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
Nervous system development R-HSA-9675108
Beta-catenin independent WNT signaling R-HSA-3858494
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
G1/S DNA Damage Checkpoints R-HSA-69615
CLEC7A (Dectin-1) signaling R-HSA-5607764
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
S Phase R-HSA-69242
Signaling by ROBO receptors R-HSA-376176
Cell Cycle Checkpoints R-HSA-69620
Host Interactions of HIV factors R-HSA-162909
Regulation of Apoptosis R-HSA-169911
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
Hh mutants abrogate ligand secretion R-HSA-5387390
Vif-mediated degradation of APOBEC3G R-HSA-180585
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic Anaphase R-HSA-68882
Regulation of expression of SLITs and ROBOs R-HSA-9010553
p53-Independent DNA Damage Response R-HSA-69610
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
TCR signaling R-HSA-202403
Hedgehog 'on' state R-HSA-5632684
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH R-HSA-157118
Interleukin-1 signaling R-HSA-9020702
DNA Replication R-HSA-69306
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
Axon guidance R-HSA-422475
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of PTEN stability and activity R-HSA-8948751
Asymmetric localization of PCP proteins R-HSA-4608870
Assembly of the pre-replicative complex R-HSA-68867
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK1/MAPK3 signaling R-HSA-5684996
Developmental Biology R-HSA-1266738
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Programmed Cell Death R-HSA-5357801
Deubiquitination R-HSA-5688426
M Phase R-HSA-68886
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Degradation of AXIN R-HSA-4641257
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G1 phase and G1/S transition R-HSA-453279
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle, Mitotic R-HSA-69278
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nervous system development R-HSA-9675108
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of polyamines R-HSA-351202
Class I MHC mediated antigen processing & presentation R-HSA-983169
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Cellular response to hypoxia R-HSA-1234174
Beta-catenin independent WNT signaling R-HSA-3858494
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of RNA R-HSA-8953854
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism R-HSA-1430728
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of RAS by GAPs R-HSA-5658442
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular responses to stimuli R-HSA-8953897
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PCP/CE pathway R-HSA-4086400
PTEN Regulation R-HSA-6807070
Generic Transcription Pathway R-HSA-212436
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic Metaphase and Anaphase R-HSA-2555396
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S Transition R-HSA-69206
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
DNA Replication Pre-Initiation R-HSA-69002
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
S Phase R-HSA-69242
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
p53-Dependent G1 DNA Damage Response R-HSA-69563
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Assembly of the pre-replicative complex R-HSA-68867
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
Cellular response to hypoxia R-HSA-1234174
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic Metaphase and Anaphase R-HSA-2555396
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Negative regulation of NOTCH4 signaling R-HSA-9604323
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog 'off' state R-HSA-5610787
Metabolism of polyamines R-HSA-351202
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of beta-catenin by the destruction complex R-HSA-195253
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
Regulation of RAS by GAPs R-HSA-5658442
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants abrogate ligand secretion R-HSA-5387390
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular responses to stimuli R-HSA-8953897
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Apoptosis R-HSA-109581
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Nervous system development R-HSA-9675108
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Vpu mediated degradation of CD4 R-HSA-180534
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
HIV Infection R-HSA-162906
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Synthesis of DNA R-HSA-69239
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Mitotic G2-G2/M phases R-HSA-453274
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'on' state R-HSA-5632684
Cell Cycle, Mitotic R-HSA-69278
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Apoptosis R-HSA-109581
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of polyamines R-HSA-351202
Degradation of DVL R-HSA-4641258
Hedgehog 'off' state R-HSA-5610787
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication Pre-Initiation R-HSA-69002
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism R-HSA-1430728
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RNA Polymerase II Transcription R-HSA-73857
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog ligand biogenesis R-HSA-5358346
Axon guidance R-HSA-422475
Signaling by Hedgehog R-HSA-5358351
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by ROBO receptors R-HSA-376176
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of beta-catenin by the destruction complex R-HSA-195253
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Antigen processing-Cross presentation R-HSA-1236975
Host Interactions of HIV factors R-HSA-162909
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
Intracellular signaling by second messengers R-HSA-9006925
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Negative regulation of NOTCH4 signaling R-HSA-9604323
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Assembly of the pre-replicative complex R-HSA-68867
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
TCF dependent signaling in response to WNT R-HSA-201681
Deubiquitination R-HSA-5688426
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Beta-catenin independent WNT signaling R-HSA-3858494
Programmed Cell Death R-HSA-5357801
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
Transport of small molecules R-HSA-382551
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
NIK-->noncanonical NF-kB signaling R-HSA-5676590
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
Adaptive Immune System R-HSA-1280218
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PTEN Regulation R-HSA-6807070
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Mitotic Metaphase and Anaphase R-HSA-2555396
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
Disease R-HSA-1643685
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of beta-catenin by the destruction complex R-HSA-195253
Switching of origins to a post-replicative state R-HSA-69052
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
ABC-family proteins mediated transport R-HSA-382556
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CLEC7A (Dectin-1) signaling R-HSA-5607764
HIV Infection R-HSA-162906
Degradation of DVL R-HSA-4641258
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Nuclear events mediated by NFE2L2 R-HSA-9759194
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Neddylation R-HSA-8951664
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
DNA Replication Pre-Initiation R-HSA-69002
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
Synthesis of DNA R-HSA-69239
Regulation of Apoptosis R-HSA-169911
Regulation of PTEN stability and activity R-HSA-8948751
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX3 expression and activity R-HSA-8941858
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle Checkpoints R-HSA-69620
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vpu mediated degradation of CD4 R-HSA-180534
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
p53-Independent DNA Damage Response R-HSA-69610
RNA Polymerase II Transcription R-HSA-73857
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
Degradation of GLI1 by the proteasome R-HSA-5610780
Cytokine Signaling in Immune system R-HSA-1280215
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
PTEN Regulation R-HSA-6807070
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
PCP/CE pathway R-HSA-4086400
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Deubiquitination R-HSA-5688426
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC transporter disorders R-HSA-5619084
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Programmed Cell Death R-HSA-5357801
Metabolism of amino acids and derivatives R-HSA-71291
Generic Transcription Pathway R-HSA-212436
Nervous system development R-HSA-9675108
Regulation of mitotic cell cycle R-HSA-453276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
Metabolism of polyamines R-HSA-351202
Vif-mediated degradation of APOBEC3G R-HSA-180585
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Signaling by Hedgehog R-HSA-5358351
Disease R-HSA-1643685
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Ub-specific processing proteases R-HSA-5689880
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Deubiquitination R-HSA-5688426
Signaling by Hedgehog R-HSA-5358351
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Assembly of the pre-replicative complex R-HSA-68867
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Synthesis of DNA R-HSA-69239
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RAS by GAPs R-HSA-5658442
Degradation of AXIN R-HSA-4641257
Signaling by WNT R-HSA-195721
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RNA Polymerase II Transcription R-HSA-73857
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Infectious disease R-HSA-5663205
Hedgehog 'off' state R-HSA-5610787
Hedgehog ligand biogenesis R-HSA-5358346
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle R-HSA-1640170
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic Metaphase and Anaphase R-HSA-2555396
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
M Phase R-HSA-68886
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of proteins R-HSA-392499
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic Anaphase R-HSA-68882
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
G1/S Transition R-HSA-69206
Signaling by NOTCH4 R-HSA-9013694
Separation of Sister Chromatids R-HSA-2467813
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Beta-catenin independent WNT signaling R-HSA-3858494
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
DNA Replication Pre-Initiation R-HSA-69002
DNA Replication R-HSA-69306
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Class I MHC mediated antigen processing & presentation R-HSA-983169
Activation of NF-kappaB in B cells R-HSA-1169091
Switching of origins to a post-replicative state R-HSA-69052
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of polyamines R-HSA-351202
Vif-mediated degradation of APOBEC3G R-HSA-180585
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Apoptosis R-HSA-109581
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
G1/S Transition R-HSA-69206
Regulation of RUNX3 expression and activity R-HSA-8941858
Vpu mediated degradation of CD4 R-HSA-180534
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Degradation of GLI1 by the proteasome R-HSA-5610780
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing-Cross presentation R-HSA-1236975
Infectious disease R-HSA-5663205
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of Apoptosis R-HSA-169911
C-type lectin receptors (CLRs) R-HSA-5621481
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
Degradation of DVL R-HSA-4641258
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Assembly of the pre-replicative complex R-HSA-68867
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Metabolism R-HSA-1430728
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX3 R-HSA-8878159
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of RAS by GAPs R-HSA-5658442
Mitotic G2-G2/M phases R-HSA-453274
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
KEAP1-NFE2L2 pathway R-HSA-9755511
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TCF dependent signaling in response to WNT R-HSA-201681
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mitotic cell cycle R-HSA-453276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Adaptive Immune System R-HSA-1280218
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Orc1 removal from chromatin R-HSA-68949
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Checkpoints R-HSA-69481
p53-Independent DNA Damage Response R-HSA-69610
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ER-Phagosome pathway R-HSA-1236974
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of AXIN R-HSA-4641257
Metabolism of polyamines R-HSA-351202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
DNA Replication R-HSA-69306
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI2 by the proteasome R-HSA-5610783
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by NOTCH R-HSA-157118
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cyclin E associated events during G1/S transition R-HSA-69202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of proteins R-HSA-392499
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
Host Interactions of HIV factors R-HSA-162909
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Orc1 removal from chromatin R-HSA-68949
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Nuclear events mediated by NFE2L2 R-HSA-9759194
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Switching of origins to a post-replicative state R-HSA-69052
Cyclin E associated events during G1/S transition R-HSA-69202
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX2 R-HSA-8878166
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of amino acids and derivatives R-HSA-71291
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
Signal Transduction R-HSA-162582
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular responses to stimuli R-HSA-8953897
Deubiquitination R-HSA-5688426
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCF dependent signaling in response to WNT R-HSA-201681
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
G2/M Transition R-HSA-69275
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Post-translational protein modification R-HSA-597592
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication Pre-Initiation R-HSA-69002
FCERI mediated NF-kB activation R-HSA-2871837
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by NOTCH R-HSA-157118
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
TCR signaling R-HSA-202403
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Gene expression (Transcription) R-HSA-74160
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX3 R-HSA-8878159
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
Assembly of the pre-replicative complex R-HSA-68867
Programmed Cell Death R-HSA-5357801
ABC-family proteins mediated transport R-HSA-382556
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants are degraded by ERAD R-HSA-5362768
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S Transition R-HSA-69206
Mitotic Anaphase R-HSA-68882
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
UCH proteinases R-HSA-5689603
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
Downstream TCR signaling R-HSA-202424
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Nervous system development R-HSA-9675108
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
PIP3 activates AKT signaling R-HSA-1257604
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PTEN Regulation R-HSA-6807070
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle Checkpoints R-HSA-69620
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cell Cycle R-HSA-1640170
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
Signaling by ROBO receptors R-HSA-376176
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Adaptive Immune System R-HSA-1280218
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
Negative regulation of NOTCH4 signaling R-HSA-9604323
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to hypoxia R-HSA-1234174
TCR signaling R-HSA-202403
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Hh mutants abrogate ligand secretion R-HSA-5387390
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Hedgehog 'off' state R-HSA-5610787
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Apoptosis R-HSA-109581
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication R-HSA-69306
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ABC transporter disorders R-HSA-5619084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of RNA R-HSA-8953854
Stabilization of p53 R-HSA-69541
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
PCP/CE pathway R-HSA-4086400
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication Pre-Initiation R-HSA-69002
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Signaling by WNT R-HSA-195721
Infectious disease R-HSA-5663205
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814

Expression Atlas ENSG00000101182
NCBI gene (formerly Entrezgene) 5688
GeneCards 9536
HGNC Symbol HGNC:9536
MIM gene 606607
UniProtKB Gene Name O14818
WikiGene 5688
Gene: AOC3
Ensembl ID : ENSG00000131471
Description: amine oxidase copper containing 3
Gene Synonyms: HPAO,VAP-1,VAP1
1 APIs:
317 Possible Orthologues:

Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859

Expression Atlas ENSG00000131471
NCBI gene (formerly Entrezgene) 8639
GeneCards 550
HGNC Symbol HGNC:550
MIM gene 603735
UniProtKB Gene Name Q16853
WikiGene 8639
Gene: PRKDC
Ensembl ID : ENSG00000253729
Description: protein kinase, DNA-activated, catalytic subunit
Gene Synonyms: DNA-PKC,DNA-PKCS,DNAPK,DNAPKC,DNPK1,HYRC,HYRC1,P350,P460,XRCC7
1 APIs:
187 Possible Orthologues:

Immune System R-HSA-168256
Protein ubiquitination R-HSA-8852135
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Repair R-HSA-73894
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
IRF3-mediated induction of type I IFN R-HSA-3270619
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
Metabolism of proteins R-HSA-392499
STING mediated induction of host immune responses R-HSA-1834941
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
IRF3-mediated induction of type I IFN R-HSA-3270619
Metabolism of proteins R-HSA-392499
DNA Double-Strand Break Repair R-HSA-5693532
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Post-translational protein modification R-HSA-597592
DNA Repair R-HSA-73894
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
STING mediated induction of host immune responses R-HSA-1834941
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
IRF3-mediated induction of type I IFN R-HSA-3270619
STING mediated induction of host immune responses R-HSA-1834941
DNA Repair R-HSA-73894
Immune System R-HSA-168256
DNA Double-Strand Break Repair R-HSA-5693532
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
DNA Repair R-HSA-73894
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
IRF3-mediated induction of type I IFN R-HSA-3270619
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
DNA Double-Strand Break Repair R-HSA-5693532
Innate Immune System R-HSA-168249
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
STING mediated induction of host immune responses R-HSA-1834941
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Post-translational protein modification R-HSA-597592
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
STING mediated induction of host immune responses R-HSA-1834941
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
DNA Repair R-HSA-73894
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
STING mediated induction of host immune responses R-HSA-1834941
DNA Double-Strand Break Repair R-HSA-5693532
IRF3-mediated induction of type I IFN R-HSA-3270619
Immune System R-HSA-168256
DNA Repair R-HSA-73894
Innate Immune System R-HSA-168249
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
IRF3-mediated induction of type I IFN R-HSA-3270619
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Repair R-HSA-73894
DNA Double-Strand Break Repair R-HSA-5693532
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135
Post-translational protein modification R-HSA-597592
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Post-translational protein modification R-HSA-597592
STING mediated induction of host immune responses R-HSA-1834941
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Innate Immune System R-HSA-168249
DNA Repair R-HSA-73894
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Innate Immune System R-HSA-168249
Metabolism of proteins R-HSA-392499
IRF3-mediated induction of type I IFN R-HSA-3270619
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
DNA Double-Strand Break Repair R-HSA-5693532
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135

Expression Atlas ENSG00000253729
LRG display in Ensembl gene LRG_162
NCBI gene (formerly Entrezgene) 5591
GeneCards 9413
HGNC Symbol HGNC:9413
MIM gene 600899
MIM morbid 615966
UniProtKB Gene Name P78527
WikiGene 5591