Gene: PSMC6
Ensembl ID : ENSG00000100519
Description: proteasome 26S subunit, ATPase 6
Gene Synonyms: P42,RPT5
5 APIs:
229 Possible Orthologues:

DNA Replication R-HSA-69306
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
HIV Infection R-HSA-162906
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH4 R-HSA-9013694
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream TCR signaling R-HSA-202424
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX3 R-HSA-8878159
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RNA Polymerase II Transcription R-HSA-73857
Neddylation R-HSA-8951664
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Host Interactions of HIV factors R-HSA-162909
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
SARS-CoV-1-host interactions R-HSA-9692914
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
ABC transporter disorders R-HSA-5619084
Developmental Biology R-HSA-1266738
SARS-CoV Infections R-HSA-9679506
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of Apoptosis R-HSA-169911
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of AXIN R-HSA-4641257
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
p53-Independent DNA Damage Response R-HSA-69610
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Vpu mediated degradation of CD4 R-HSA-180534
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
SARS-CoV-1-host interactions R-HSA-9692914
UCH proteinases R-HSA-5689603
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of Apoptosis R-HSA-169911
Regulation of PTEN stability and activity R-HSA-8948751
Synthesis of DNA R-HSA-69239
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
G2/M Transition R-HSA-69275
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of amino acids and derivatives R-HSA-71291
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Developmental Biology R-HSA-1266738
Post-translational protein modification R-HSA-597592
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream TCR signaling R-HSA-202424
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1 DNA Damage Response R-HSA-69563
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1 Infection R-HSA-9678108
HIV Infection R-HSA-162906
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G2-G2/M phases R-HSA-453274
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants abrogate ligand secretion R-HSA-5387390
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Assembly of the pre-replicative complex R-HSA-68867
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Vpu mediated degradation of CD4 R-HSA-180534
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Innate Immune System R-HSA-168249
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
SARS-CoV-1 Infection R-HSA-9678108
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'off' state R-HSA-5610787
G1/S Transition R-HSA-69206
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of beta-catenin by the destruction complex R-HSA-195253
Developmental Biology R-HSA-1266738
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV Infections R-HSA-9679506
Signaling by Hedgehog R-HSA-5358351
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by WNT R-HSA-195721
HIV Infection R-HSA-162906
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Post-translational protein modification R-HSA-597592
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Beta-catenin independent WNT signaling R-HSA-3858494
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Deubiquitination R-HSA-5688426
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Cell Cycle, Mitotic R-HSA-69278
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Degradation of AXIN R-HSA-4641257
Regulation of RAS by GAPs R-HSA-5658442
Orc1 removal from chromatin R-HSA-68949
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Adaptive Immune System R-HSA-1280218
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
SARS-CoV-1 Infection R-HSA-9678108
Cellular responses to stimuli R-HSA-8953897
Signaling by NOTCH R-HSA-157118
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle R-HSA-1640170
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cyclin E associated events during G1/S transition R-HSA-69202
M Phase R-HSA-68886
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SARS-CoV Infections R-HSA-9679506
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
Negative regulation of NOTCH4 signaling R-HSA-9604323
SARS-CoV-1-host interactions R-HSA-9692914
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC-family proteins mediated transport R-HSA-382556
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX2 expression and activity R-HSA-8939902
Transport of small molecules R-HSA-382551
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of DVL R-HSA-4641258
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'off' state R-HSA-5610787
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Interleukin-1 signaling R-HSA-9020702
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Checkpoints R-HSA-69481
SARS-CoV-1 Infection R-HSA-9678108
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FCERI mediated NF-kB activation R-HSA-2871837
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disorders of transmembrane transporters R-HSA-5619115
SARS-CoV-1-host interactions R-HSA-9692914
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
SARS-CoV Infections R-HSA-9679506
ER-Phagosome pathway R-HSA-1236974
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Synthesis of DNA R-HSA-69239
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism R-HSA-1430728
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of mitotic cell cycle R-HSA-453276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
Adaptive Immune System R-HSA-1280218
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
KEAP1-NFE2L2 pathway R-HSA-9755511
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Interleukins R-HSA-449147
p53-Independent DNA Damage Response R-HSA-69610
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular responses to stimuli R-HSA-8953897
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Separation of Sister Chromatids R-HSA-2467813
Axon guidance R-HSA-422475
SARS-CoV-1 Infection R-HSA-9678108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Regulation of Apoptosis R-HSA-169911
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PTEN Regulation R-HSA-6807070
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
HIV Infection R-HSA-162906
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SARS-CoV Infections R-HSA-9679506
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Asymmetric localization of PCP proteins R-HSA-4608870
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
Regulation of Apoptosis R-HSA-169911
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream TCR signaling R-HSA-202424
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic Metaphase and Anaphase R-HSA-2555396
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants are degraded by ERAD R-HSA-5362768
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PTEN stability and activity R-HSA-8948751
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
p53-Independent DNA Damage Response R-HSA-69610
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stimuli R-HSA-8953897
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
SARS-CoV Infections R-HSA-9679506
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH R-HSA-157118
SARS-CoV-1 Infection R-HSA-9678108
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Asymmetric localization of PCP proteins R-HSA-4608870
CLEC7A (Dectin-1) signaling R-HSA-5607764
Neddylation R-HSA-8951664
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Post-translational protein modification R-HSA-597592
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PTEN Regulation R-HSA-6807070
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Cytokine Signaling in Immune system R-HSA-1280215
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Synthesis of DNA R-HSA-69239
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
S Phase R-HSA-69242
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Adaptive Immune System R-HSA-1280218
Nervous system development R-HSA-9675108
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by WNT R-HSA-195721
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism R-HSA-1430728
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
RAF/MAP kinase cascade R-HSA-5673001
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 signaling R-HSA-9020702
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle Checkpoints R-HSA-69620
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Gene expression (Transcription) R-HSA-74160
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle, Mitotic R-HSA-69278
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Developmental Biology R-HSA-1266738
SARS-CoV-1 Infection R-HSA-9678108
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX1 R-HSA-8878171
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G2-G2/M phases R-HSA-453274
Degradation of GLI1 by the proteasome R-HSA-5610780
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH R-HSA-157118
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Deubiquitination R-HSA-5688426
Neddylation R-HSA-8951664
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 signaling R-HSA-9020702
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Hh mutants are degraded by ERAD R-HSA-5362768
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
SARS-CoV-1 Infection R-HSA-9678108
DNA Replication R-HSA-69306
M Phase R-HSA-68886
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
SARS-CoV-1-host interactions R-HSA-9692914
Apoptosis R-HSA-109581
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
UCH proteinases R-HSA-5689603
Degradation of GLI2 by the proteasome R-HSA-5610783
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
SARS-CoV Infections R-HSA-9679506
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of beta-catenin by the destruction complex R-HSA-195253
S Phase R-HSA-69242
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Disorders of transmembrane transporters R-HSA-5619115
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of amino acids and derivatives R-HSA-71291
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of mitotic cell cycle R-HSA-453276
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
Transport of small molecules R-HSA-382551
Beta-catenin independent WNT signaling R-HSA-3858494
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
Metabolism of polyamines R-HSA-351202
SARS-CoV-1 Infection R-HSA-9678108
DNA Replication Pre-Initiation R-HSA-69002
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
G1/S Transition R-HSA-69206
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RAF/MAP kinase cascade R-HSA-5673001
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
Neddylation R-HSA-8951664
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
SARS-CoV-1-host interactions R-HSA-9692914
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Stabilization of p53 R-HSA-69541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants are degraded by ERAD R-HSA-5362768
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SARS-CoV-1 Infection R-HSA-9678108
Metabolism of amino acids and derivatives R-HSA-71291
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Cell Cycle R-HSA-1640170
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Host Interactions of HIV factors R-HSA-162909
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH4 R-HSA-9013694
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX2 expression and activity R-HSA-8939902
Transport of small molecules R-HSA-382551
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Negative regulation of NOTCH4 signaling R-HSA-9604323
Assembly of the pre-replicative complex R-HSA-68867
SARS-CoV Infections R-HSA-9679506
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCF dependent signaling in response to WNT R-HSA-201681
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603

Expression Atlas ENSG00000100519
NCBI gene (formerly Entrezgene) 5706
GeneCards 9553
HGNC Symbol HGNC:9553
MIM gene 602708
UniProtKB Gene Name P62333
WikiGene 5706
Ensembl ID : ENSG00000096384
Description: heat shock protein 90 alpha family class B member 1
Gene Synonyms: HSPC2,HSPCB
9 APIs:
198 Possible Orthologues:

Biological oxidations R-HSA-211859
RHOBTB GTPase Cycle R-HSA-9706574
ESR-mediated signaling R-HSA-8939211
Innate Immune System R-HSA-168249
Signaling by Nuclear Receptors R-HSA-9006931
Uptake and function of diphtheria toxin R-HSA-5336415
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Attenuation phase R-HSA-3371568
Disease R-HSA-1643685
RHOBTB GTPase Cycle R-HSA-9706574
Cell Cycle, Mitotic R-HSA-69278
Chaperone Mediated Autophagy R-HSA-9613829
Cell Cycle R-HSA-1640170
Cellular response to heat stress R-HSA-3371556
SARS-CoV-2 Infection R-HSA-9694516
G2/M Transition R-HSA-69275
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Phase I - Functionalization of compounds R-HSA-211945
RHO GTPase cycle R-HSA-9012999
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Semaphorin interactions R-HSA-373755
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Aryl hydrocarbon receptor signalling R-HSA-8937144
Estrogen-dependent gene expression R-HSA-9018519
Sema3A PAK dependent Axon repulsion R-HSA-399954
HSF1-dependent transactivation R-HSA-3371571
Biological oxidations R-HSA-211859
Uptake and actions of bacterial toxins R-HSA-5339562
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Autophagy R-HSA-9612973
Cellular responses to stress R-HSA-2262752
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
The NLRP3 inflammasome R-HSA-844456
SARS-CoV Infections R-HSA-9679506
HSF1 activation R-HSA-3371511
Inflammasomes R-HSA-622312
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Developmental Biology R-HSA-1266738
Mitotic G2-G2/M phases R-HSA-453274
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Leishmania infection R-HSA-9658195
RHOBTB2 GTPase cycle R-HSA-9013418
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Immune System R-HSA-168256
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Attenuation phase R-HSA-3371568
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G2-G2/M phases R-HSA-453274
Semaphorin interactions R-HSA-373755
Autophagy R-HSA-9612973
Infectious disease R-HSA-5663205
Chaperone Mediated Autophagy R-HSA-9613829
Aryl hydrocarbon receptor signalling R-HSA-8937144
Leishmania infection R-HSA-9658195
Cell recruitment (pro-inflammatory response) R-HSA-9664424
SARS-CoV-2 Infection R-HSA-9694516
G2/M Transition R-HSA-69275
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Metabolism R-HSA-1430728
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
HSF1-dependent transactivation R-HSA-3371571
Inflammasomes R-HSA-622312
Uptake and function of diphtheria toxin R-HSA-5336415
Signaling by Nuclear Receptors R-HSA-9006931
Cell Cycle, Mitotic R-HSA-69278
SARS-CoV-2-host interactions R-HSA-9705683
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Potential therapeutics for SARS R-HSA-9679191
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
RHOBTB GTPase Cycle R-HSA-9706574
Phase I - Functionalization of compounds R-HSA-211945
Cellular response to heat stress R-HSA-3371556
SARS-CoV Infections R-HSA-9679506
The NLRP3 inflammasome R-HSA-844456
RHO GTPase cycle R-HSA-9012999
Uptake and actions of bacterial toxins R-HSA-5339562
Sema3A PAK dependent Axon repulsion R-HSA-399954
Signal Transduction R-HSA-162582
Neutrophil degranulation R-HSA-6798695
HSF1 activation R-HSA-3371511
Cellular responses to stimuli R-HSA-8953897
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nervous system development R-HSA-9675108
Signaling by Rho GTPases R-HSA-194315
Estrogen-dependent gene expression R-HSA-9018519
RHOBTB2 GTPase cycle R-HSA-9013418
Cell Cycle R-HSA-1640170
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
ESR-mediated signaling R-HSA-8939211
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
The NLRP3 inflammasome R-HSA-844456
Metabolism R-HSA-1430728
HSF1 activation R-HSA-3371511
Potential therapeutics for SARS R-HSA-9679191
Cellular responses to stimuli R-HSA-8953897
SARS-CoV-2 Infection R-HSA-9694516
Cellular response to heat stress R-HSA-3371556
Autophagy R-HSA-9612973
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Inflammasomes R-HSA-622312
RHOBTB GTPase Cycle R-HSA-9706574
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Attenuation phase R-HSA-3371568
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
SARS-CoV Infections R-HSA-9679506
Uptake and actions of bacterial toxins R-HSA-5339562
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Leishmania infection R-HSA-9658195
RHOBTB2 GTPase cycle R-HSA-9013418
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Uptake and function of diphtheria toxin R-HSA-5336415
Signal Transduction R-HSA-162582
Aryl hydrocarbon receptor signalling R-HSA-8937144
Developmental Biology R-HSA-1266738
Cell recruitment (pro-inflammatory response) R-HSA-9664424
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Phase I - Functionalization of compounds R-HSA-211945
Sema3A PAK dependent Axon repulsion R-HSA-399954
HSF1-dependent transactivation R-HSA-3371571
Cell Cycle, Mitotic R-HSA-69278
Signaling by Rho GTPases R-HSA-194315
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Infectious disease R-HSA-5663205
G2/M Transition R-HSA-69275
Biological oxidations R-HSA-211859
Immune System R-HSA-168256
RHO GTPase cycle R-HSA-9012999
SARS-CoV-2-host interactions R-HSA-9705683
Semaphorin interactions R-HSA-373755
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
ESR-mediated signaling R-HSA-8939211
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cellular responses to stress R-HSA-2262752
Chaperone Mediated Autophagy R-HSA-9613829
Estrogen-dependent gene expression R-HSA-9018519
Semaphorin interactions R-HSA-373755
Cellular response to heat stress R-HSA-3371556
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
The NLRP3 inflammasome R-HSA-844456
SARS-CoV Infections R-HSA-9679506
Immune System R-HSA-168256
HSF1 activation R-HSA-3371511
Innate Immune System R-HSA-168249
Inflammasomes R-HSA-622312
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Signaling by Nuclear Receptors R-HSA-9006931
HSF1-dependent transactivation R-HSA-3371571
Biological oxidations R-HSA-211859
SARS-CoV-2 Infection R-HSA-9694516
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Autophagy R-HSA-9612973
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Potential therapeutics for SARS R-HSA-9679191
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases R-HSA-194315
Aryl hydrocarbon receptor signalling R-HSA-8937144
G2/M Transition R-HSA-69275
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Purinergic signaling in leishmaniasis infection R-HSA-9660826
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Infectious disease R-HSA-5663205
RHO GTPase cycle R-HSA-9012999
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Phase I - Functionalization of compounds R-HSA-211945
SARS-CoV-2-host interactions R-HSA-9705683
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Estrogen-dependent gene expression R-HSA-9018519
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Mitotic G2-G2/M phases R-HSA-453274
Sema3A PAK dependent Axon repulsion R-HSA-399954
Nervous system development R-HSA-9675108
Uptake and actions of bacterial toxins R-HSA-5339562
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Attenuation phase R-HSA-3371568
Cellular responses to stress R-HSA-2262752
Uptake and function of diphtheria toxin R-HSA-5336415
Neutrophil degranulation R-HSA-6798695
RHOBTB2 GTPase cycle R-HSA-9013418
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism R-HSA-1430728
Chaperone Mediated Autophagy R-HSA-9613829
Cell Cycle R-HSA-1640170
HSF1 activation R-HSA-3371511
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Neutrophil degranulation R-HSA-6798695
SARS-CoV Infections R-HSA-9679506
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Autophagy R-HSA-9612973
Immune System R-HSA-168256
Uptake and actions of bacterial toxins R-HSA-5339562
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Biological oxidations R-HSA-211859
Mitotic G2-G2/M phases R-HSA-453274
Cellular response to heat stress R-HSA-3371556
Semaphorin interactions R-HSA-373755
HSF1-dependent transactivation R-HSA-3371571
Axon guidance R-HSA-422475
RHO GTPase cycle R-HSA-9012999
Sema3A PAK dependent Axon repulsion R-HSA-399954
Leishmania infection R-HSA-9658195
SARS-CoV-2 Infection R-HSA-9694516
RHOBTB2 GTPase cycle R-HSA-9013418
Cellular responses to stimuli R-HSA-8953897
Potential therapeutics for SARS R-HSA-9679191
ESR-mediated signaling R-HSA-8939211
Cell Cycle R-HSA-1640170
SARS-CoV-2-host interactions R-HSA-9705683
Infectious disease R-HSA-5663205
Attenuation phase R-HSA-3371568
Disease R-HSA-1643685
RHOBTB GTPase Cycle R-HSA-9706574
Nervous system development R-HSA-9675108
Signaling by Rho GTPases R-HSA-194315
Aryl hydrocarbon receptor signalling R-HSA-8937144
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle, Mitotic R-HSA-69278
The NLRP3 inflammasome R-HSA-844456
G2/M Transition R-HSA-69275
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
Inflammasomes R-HSA-622312
Uptake and function of diphtheria toxin R-HSA-5336415
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by Nuclear Receptors R-HSA-9006931
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Estrogen-dependent gene expression R-HSA-9018519
Chaperone Mediated Autophagy R-HSA-9613829
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Innate Immune System R-HSA-168249
Phase I - Functionalization of compounds R-HSA-211945
Chaperone Mediated Autophagy R-HSA-9613829
Potential therapeutics for SARS R-HSA-9679191
Cell Cycle R-HSA-1640170
The NLRP3 inflammasome R-HSA-844456
Immune System R-HSA-168256
RHOBTB GTPase Cycle R-HSA-9706574
ESR-mediated signaling R-HSA-8939211
RHO GTPase cycle R-HSA-9012999
Nervous system development R-HSA-9675108
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism R-HSA-1430728
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cellular response to heat stress R-HSA-3371556
Uptake and function of diphtheria toxin R-HSA-5336415
Uptake and actions of bacterial toxins R-HSA-5339562
HSF1-dependent transactivation R-HSA-3371571
Semaphorin interactions R-HSA-373755
Signal Transduction R-HSA-162582
HSF1 activation R-HSA-3371511
SARS-CoV-2 Infection R-HSA-9694516
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell Cycle, Mitotic R-HSA-69278
Axon guidance R-HSA-422475
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Attenuation phase R-HSA-3371568
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Neutrophil degranulation R-HSA-6798695
Cellular responses to stimuli R-HSA-8953897
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Inflammasomes R-HSA-622312
Biological oxidations R-HSA-211859
Signaling by Nuclear Receptors R-HSA-9006931
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Phase I - Functionalization of compounds R-HSA-211945
Leishmania infection R-HSA-9658195
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Aryl hydrocarbon receptor signalling R-HSA-8937144
G2/M Transition R-HSA-69275
Autophagy R-HSA-9612973
Cellular responses to stress R-HSA-2262752
Infectious disease R-HSA-5663205
Sema3A PAK dependent Axon repulsion R-HSA-399954
RHOBTB2 GTPase cycle R-HSA-9013418
Mitotic G2-G2/M phases R-HSA-453274
Estrogen-dependent gene expression R-HSA-9018519
Purinergic signaling in leishmaniasis infection R-HSA-9660826
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Rho GTPases R-HSA-194315
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Estrogen-dependent gene expression R-HSA-9018519
Infectious disease R-HSA-5663205
RHO GTPase cycle R-HSA-9012999
Semaphorin interactions R-HSA-373755
Autophagy R-HSA-9612973
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
The NLRP3 inflammasome R-HSA-844456
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Biological oxidations R-HSA-211859
Mitotic G2-G2/M phases R-HSA-453274
SARS-CoV Infections R-HSA-9679506
Aryl hydrocarbon receptor signalling R-HSA-8937144
RHOBTB GTPase Cycle R-HSA-9706574
Chaperone Mediated Autophagy R-HSA-9613829
Signaling by Nuclear Receptors R-HSA-9006931
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
SARS-CoV-2-host interactions R-HSA-9705683
Cell Cycle, Mitotic R-HSA-69278
HSF1 activation R-HSA-3371511
SARS-CoV-2 Infection R-HSA-9694516
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Leishmania infection R-HSA-9658195
Phase I - Functionalization of compounds R-HSA-211945
Potential therapeutics for SARS R-HSA-9679191
Uptake and actions of bacterial toxins R-HSA-5339562
RHOBTB2 GTPase cycle R-HSA-9013418
Inflammasomes R-HSA-622312
Axon guidance R-HSA-422475
Uptake and function of diphtheria toxin R-HSA-5336415
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Attenuation phase R-HSA-3371568
G2/M Transition R-HSA-69275
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Developmental Biology R-HSA-1266738
Sema3A PAK dependent Axon repulsion R-HSA-399954
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cell Cycle R-HSA-1640170
HSF1-dependent transactivation R-HSA-3371571
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Cellular response to heat stress R-HSA-3371556
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
ESR-mediated signaling R-HSA-8939211
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cellular responses to stress R-HSA-2262752
ESR-mediated signaling R-HSA-8939211
SARS-CoV-2-host interactions R-HSA-9705683
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Inflammasomes R-HSA-622312
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Infectious disease R-HSA-5663205
RHOBTB GTPase Cycle R-HSA-9706574
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Sema3A PAK dependent Axon repulsion R-HSA-399954
Semaphorin interactions R-HSA-373755
Cellular responses to stimuli R-HSA-8953897
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-2 Infection R-HSA-9694516
RHO GTPase cycle R-HSA-9012999
G2/M Transition R-HSA-69275
Uptake and function of diphtheria toxin R-HSA-5336415
Signal Transduction R-HSA-162582
Chaperone Mediated Autophagy R-HSA-9613829
HSF1 activation R-HSA-3371511
HSF1-dependent transactivation R-HSA-3371571
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Innate Immune System R-HSA-168249
The NLRP3 inflammasome R-HSA-844456
Uptake and actions of bacterial toxins R-HSA-5339562
Developmental Biology R-HSA-1266738
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Cellular response to heat stress R-HSA-3371556
Neutrophil degranulation R-HSA-6798695
Cell Cycle R-HSA-1640170
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Signaling by Nuclear Receptors R-HSA-9006931
Potential therapeutics for SARS R-HSA-9679191
Biological oxidations R-HSA-211859
Estrogen-dependent gene expression R-HSA-9018519
Cell Cycle, Mitotic R-HSA-69278
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Aryl hydrocarbon receptor signalling R-HSA-8937144
Immune System R-HSA-168256
Leishmania infection R-HSA-9658195
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RHOBTB2 GTPase cycle R-HSA-9013418
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nervous system development R-HSA-9675108
Attenuation phase R-HSA-3371568
Autophagy R-HSA-9612973
SARS-CoV Infections R-HSA-9679506
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
Potential therapeutics for SARS R-HSA-9679191
Biological oxidations R-HSA-211859
HSF1 activation R-HSA-3371511
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular responses to stress R-HSA-2262752
Phase I - Functionalization of compounds R-HSA-211945
SARS-CoV Infections R-HSA-9679506
Uptake and actions of bacterial toxins R-HSA-5339562
The NLRP3 inflammasome R-HSA-844456
ESR-mediated signaling R-HSA-8939211
Estrogen-dependent gene expression R-HSA-9018519
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
Neutrophil degranulation R-HSA-6798695
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Inflammasomes R-HSA-622312
Signaling by Nuclear Receptors R-HSA-9006931
Immune System R-HSA-168256
Chaperone Mediated Autophagy R-HSA-9613829
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Infectious disease R-HSA-5663205
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
SARS-CoV-2-host interactions R-HSA-9705683
Aryl hydrocarbon receptor signalling R-HSA-8937144
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Attenuation phase R-HSA-3371568
Disease R-HSA-1643685
Cellular response to heat stress R-HSA-3371556
Autophagy R-HSA-9612973
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497
Signaling by Rho GTPases R-HSA-194315
RHOBTB2 GTPase cycle R-HSA-9013418
RHO GTPase cycle R-HSA-9012999
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Leishmania infection R-HSA-9658195
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cell Cycle R-HSA-1640170
Uptake and function of diphtheria toxin R-HSA-5336415
Signal Transduction R-HSA-162582
HSF1-dependent transactivation R-HSA-3371571
RHOBTB GTPase Cycle R-HSA-9706574
Cell Cycle, Mitotic R-HSA-69278
Sema3A PAK dependent Axon repulsion R-HSA-399954
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Semaphorin interactions R-HSA-373755
SARS-CoV-2 Infection R-HSA-9694516
G2/M Transition R-HSA-69275
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480

Expression Atlas ENSG00000096384
NCBI gene (formerly Entrezgene) 3326
GeneCards 5258
HGNC Symbol HGNC:5258
MIM gene 140572
UniProtKB Gene Name P08238
WikiGene 3326
Gene: PSMB1
Ensembl ID : ENSG00000008018
Description: proteasome 20S subunit beta 1
Gene Synonyms: HC5,PMSB1
6 APIs:
217 Possible Orthologues:

Metabolism R-HSA-1430728
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Innate Immune System R-HSA-168249
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog ligand biogenesis R-HSA-5358346
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of RAS by GAPs R-HSA-5658442
Transport of small molecules R-HSA-382551
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of proteins R-HSA-392499
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Separation of Sister Chromatids R-HSA-2467813
Hedgehog 'off' state R-HSA-5610787
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
DNA Replication Pre-Initiation R-HSA-69002
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
Adaptive Immune System R-HSA-1280218
Degradation of DVL R-HSA-4641258
Intracellular signaling by second messengers R-HSA-9006925
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PTEN Regulation R-HSA-6807070
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
M Phase R-HSA-68886
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of PTEN stability and activity R-HSA-8948751
Defective CFTR causes cystic fibrosis R-HSA-5678895
CLEC7A (Dectin-1) signaling R-HSA-5607764
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Mitotic G2-G2/M phases R-HSA-453274
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI1 by the proteasome R-HSA-5610780
Signal Transduction R-HSA-162582
Metabolism of polyamines R-HSA-351202
Vif-mediated degradation of APOBEC3G R-HSA-180585
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle Checkpoints R-HSA-69620
Metabolism R-HSA-1430728
ABC transporter disorders R-HSA-5619084
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
FCERI mediated NF-kB activation R-HSA-2871837
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH4 R-HSA-9013694
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Apoptosis R-HSA-109581
Cell Cycle R-HSA-1640170
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Orc1 removal from chromatin R-HSA-68949
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Metaphase and Anaphase R-HSA-2555396
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 family signaling R-HSA-446652
G2/M Transition R-HSA-69275
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cell Cycle, Mitotic R-HSA-69278
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Stabilization of p53 R-HSA-69541
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Transcriptional regulation by RUNX2 R-HSA-8878166
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'on' state R-HSA-5632684
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of RNA R-HSA-8953854
M Phase R-HSA-68886
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
HIV Infection R-HSA-162906
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 family signaling R-HSA-446652
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Activation of NF-kappaB in B cells R-HSA-1169091
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Neutrophil degranulation R-HSA-6798695
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of proteins R-HSA-392499
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of NOTCH4 signaling R-HSA-9604323
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Neddylation R-HSA-8951664
PTEN Regulation R-HSA-6807070
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Apoptosis R-HSA-109581
Hedgehog 'off' state R-HSA-5610787
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
FCERI mediated NF-kB activation R-HSA-2871837
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism R-HSA-1430728
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
RAF/MAP kinase cascade R-HSA-5673001
C-type lectin receptors (CLRs) R-HSA-5621481
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Orc1 removal from chromatin R-HSA-68949
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ub-specific processing proteases R-HSA-5689880
Transcriptional regulation by RUNX3 R-HSA-8878159
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX1 R-HSA-8878171
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by WNT R-HSA-195721
Signaling by Interleukins R-HSA-449147
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
G2/M Transition R-HSA-69275
Disease R-HSA-1643685
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
Cellular responses to stress R-HSA-2262752
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transport of small molecules R-HSA-382551
DNA Replication R-HSA-69306
Signal Transduction R-HSA-162582
Cellular response to hypoxia R-HSA-1234174
Regulation of PTEN stability and activity R-HSA-8948751
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
TCF dependent signaling in response to WNT R-HSA-201681
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Generic Transcription Pathway R-HSA-212436
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of beta-catenin by the destruction complex R-HSA-195253
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Hedgehog R-HSA-5358351
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Intracellular signaling by second messengers R-HSA-9006925
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX2 R-HSA-8878166
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX3 expression and activity R-HSA-8941858
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'on' state R-HSA-5632684
Metabolism of polyamines R-HSA-351202
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by Hedgehog R-HSA-5358351
TCF dependent signaling in response to WNT R-HSA-201681
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
Infectious disease R-HSA-5663205
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle, Mitotic R-HSA-69278
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by ROBO receptors R-HSA-376176
Transcriptional regulation by RUNX3 R-HSA-8878159
TCR signaling R-HSA-202403
KEAP1-NFE2L2 pathway R-HSA-9755511
Interleukin-1 signaling R-HSA-9020702
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of GLI1 by the proteasome R-HSA-5610780
Separation of Sister Chromatids R-HSA-2467813
Signaling by Interleukins R-HSA-449147
Regulation of Apoptosis R-HSA-169911
HIV Infection R-HSA-162906
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
Innate Immune System R-HSA-168249
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants are degraded by ERAD R-HSA-5362768
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Cytokine Signaling in Immune system R-HSA-1280215
G1/S Transition R-HSA-69206
Disorders of transmembrane transporters R-HSA-5619115
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH R-HSA-157118
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
RAF/MAP kinase cascade R-HSA-5673001
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Host Interactions of HIV factors R-HSA-162909
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ABC transporter disorders R-HSA-5619084
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular response to hypoxia R-HSA-1234174
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Signaling by WNT R-HSA-195721
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Activation of NF-kappaB in B cells R-HSA-1169091
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ub-specific processing proteases R-HSA-5689880
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stress R-HSA-2262752
Degradation of GLI2 by the proteasome R-HSA-5610783
Axon guidance R-HSA-422475
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Stabilization of p53 R-HSA-69541
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mitotic cell cycle R-HSA-453276
Vif-mediated degradation of APOBEC3G R-HSA-180585
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic G1 phase and G1/S transition R-HSA-453279
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RNA Polymerase II Transcription R-HSA-73857
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Separation of Sister Chromatids R-HSA-2467813
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of beta-catenin by the destruction complex R-HSA-195253
Mitotic G2-G2/M phases R-HSA-453274
Nervous system development R-HSA-9675108
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Metaphase and Anaphase R-HSA-2555396
Cytokine Signaling in Immune system R-HSA-1280215
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
C-type lectin receptors (CLRs) R-HSA-5621481
DNA Replication Pre-Initiation R-HSA-69002
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RAS by GAPs R-HSA-5658442
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
G1/S Transition R-HSA-69206
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to chemical stress R-HSA-9711123
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of Apoptosis R-HSA-169911
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Programmed Cell Death R-HSA-5357801
Orc1 removal from chromatin R-HSA-68949
Stabilization of p53 R-HSA-69541
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
PTEN Regulation R-HSA-6807070
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Interleukin-1 signaling R-HSA-9020702
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of DVL R-HSA-4641258
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by Hedgehog R-HSA-5358351
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Immune System R-HSA-168256
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disorders of transmembrane transporters R-HSA-5619115
Generic Transcription Pathway R-HSA-212436
Assembly of the pre-replicative complex R-HSA-68867
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Host Interactions of HIV factors R-HSA-162909
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle, Mitotic R-HSA-69278
Metabolism R-HSA-1430728
Hedgehog 'on' state R-HSA-5632684
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Independent DNA Damage Response R-HSA-69610
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Gene expression (Transcription) R-HSA-74160
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Degradation of AXIN R-HSA-4641257
Signaling by NOTCH R-HSA-157118
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
Signaling by WNT R-HSA-195721
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of DVL R-HSA-4641258
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Intracellular signaling by second messengers R-HSA-9006925
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Mitotic G1 phase and G1/S transition R-HSA-453279
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Assembly of the pre-replicative complex R-HSA-68867
p53-Dependent G1 DNA Damage Response R-HSA-69563
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Nervous system development R-HSA-9675108
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Cellular responses to stimuli R-HSA-8953897
Downstream TCR signaling R-HSA-202424
Signaling by Interleukins R-HSA-449147
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cytokine Signaling in Immune system R-HSA-1280215
Cell Cycle Checkpoints R-HSA-69620
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication R-HSA-69306
Mitotic Anaphase R-HSA-68882
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Deubiquitination R-HSA-5688426
Signaling by ROBO receptors R-HSA-376176
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Nuclear events mediated by NFE2L2 R-HSA-9759194
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of polyamines R-HSA-351202
Regulation of RAS by GAPs R-HSA-5658442
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX2 expression and activity R-HSA-8939902
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCERI mediated NF-kB activation R-HSA-2871837
Disorders of transmembrane transporters R-HSA-5619115
MAPK6/MAPK4 signaling R-HSA-5687128
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
G1/S Transition R-HSA-69206
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Degradation of GLI2 by the proteasome R-HSA-5610783
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Transition R-HSA-69275
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX1 R-HSA-8878171
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by NOTCH R-HSA-157118
Host Interactions of HIV factors R-HSA-162909
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Regulation of PTEN stability and activity R-HSA-8948751
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
UCH proteinases R-HSA-5689603
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hh mutants abrogate ligand secretion R-HSA-5387390
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of proteins R-HSA-392499
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neutrophil degranulation R-HSA-6798695
RAF/MAP kinase cascade R-HSA-5673001
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of AXIN R-HSA-4641257
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication Pre-Initiation R-HSA-69002
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
Cellular response to chemical stress R-HSA-9711123
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
ABC-family proteins mediated transport R-HSA-382556
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
Ub-specific processing proteases R-HSA-5689880
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1 DNA Damage Response R-HSA-69563
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Stabilization of p53 R-HSA-69541
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by WNT R-HSA-195721
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism of proteins R-HSA-392499
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Host Interactions of HIV factors R-HSA-162909
Cell Cycle R-HSA-1640170
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of expression of SLITs and ROBOs R-HSA-9010553
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism R-HSA-1430728
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
DNA Replication Pre-Initiation R-HSA-69002
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Downstream TCR signaling R-HSA-202424
Synthesis of DNA R-HSA-69239
Signaling by ROBO receptors R-HSA-376176
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Independent DNA Damage Response R-HSA-69610
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nuclear events mediated by NFE2L2 R-HSA-9759194
Adaptive Immune System R-HSA-1280218
Developmental Biology R-HSA-1266738
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RUNX2 expression and activity R-HSA-8939902
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stimuli R-HSA-8953897
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
G1/S Transition R-HSA-69206
Signaling by Hedgehog R-HSA-5358351
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
M Phase R-HSA-68886
Cellular response to hypoxia R-HSA-1234174
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Anaphase R-HSA-68882
MAPK family signaling cascades R-HSA-5683057
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle Checkpoints R-HSA-69620
Regulation of RAS by GAPs R-HSA-5658442
ER-Phagosome pathway R-HSA-1236974
Signaling by Interleukins R-HSA-449147
UCH proteinases R-HSA-5689603
Orc1 removal from chromatin R-HSA-68949
Transport of small molecules R-HSA-382551
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Metabolism of polyamines R-HSA-351202
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
S Phase R-HSA-69242
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Axon guidance R-HSA-422475
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Asymmetric localization of PCP proteins R-HSA-4608870
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 signaling R-HSA-9020702
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of GLI1 by the proteasome R-HSA-5610780
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cytokine Signaling in Immune system R-HSA-1280215
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
PTEN Regulation R-HSA-6807070
ABC transporter disorders R-HSA-5619084
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX2 expression and activity R-HSA-8939902
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX2 R-HSA-8878166
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
TCF dependent signaling in response to WNT R-HSA-201681
Asymmetric localization of PCP proteins R-HSA-4608870
Cellular responses to stress R-HSA-2262752
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Vpu mediated degradation of CD4 R-HSA-180534
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Checkpoints R-HSA-69481
Signaling by NOTCH R-HSA-157118
Degradation of DVL R-HSA-4641258
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Synthesis of DNA R-HSA-69239
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Cellular response to hypoxia R-HSA-1234174
Infectious disease R-HSA-5663205
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
Regulation of mitotic cell cycle R-HSA-453276
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Interleukin-1 family signaling R-HSA-446652
Hh mutants are degraded by ERAD R-HSA-5362768
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Separation of Sister Chromatids R-HSA-2467813
Axon guidance R-HSA-422475
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of RAS by GAPs R-HSA-5658442
Generic Transcription Pathway R-HSA-212436
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of NF-kappaB in B cells R-HSA-1169091
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
Adaptive Immune System R-HSA-1280218
Cellular responses to stimuli R-HSA-8953897
Metabolism of polyamines R-HSA-351202
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
Generic Transcription Pathway R-HSA-212436
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog 'on' state R-HSA-5632684
Degradation of AXIN R-HSA-4641257
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Developmental Biology R-HSA-1266738
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Interleukin-1 family signaling R-HSA-446652
RAF/MAP kinase cascade R-HSA-5673001
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of Apoptosis R-HSA-169911
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Switching of origins to a post-replicative state R-HSA-69052
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Metaphase and Anaphase R-HSA-2555396
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stress R-HSA-2262752
Assembly of the pre-replicative complex R-HSA-68867
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
Intracellular signaling by second messengers R-HSA-9006925
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC transporter disorders R-HSA-5619084
DNA Replication Pre-Initiation R-HSA-69002
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G1 phase and G1/S transition R-HSA-453279
Programmed Cell Death R-HSA-5357801
KEAP1-NFE2L2 pathway R-HSA-9755511
Host Interactions of HIV factors R-HSA-162909
PCP/CE pathway R-HSA-4086400
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'off' state R-HSA-5610787
M Phase R-HSA-68886
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Interleukin-1 signaling R-HSA-9020702
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH4 R-HSA-9013694
Regulation of PTEN stability and activity R-HSA-8948751
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
PIP3 activates AKT signaling R-HSA-1257604
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
G1/S Transition R-HSA-69206
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transport of small molecules R-HSA-382551
Metabolism of RNA R-HSA-8953854
Axon guidance R-HSA-422475
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of DVL R-HSA-4641258
Ub-specific processing proteases R-HSA-5689880
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by Hedgehog R-HSA-5358351
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Activation of NF-kappaB in B cells R-HSA-1169091
Orc1 removal from chromatin R-HSA-68949
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of RNA R-HSA-8953854
G2/M Transition R-HSA-69275
DNA Replication R-HSA-69306
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Separation of Sister Chromatids R-HSA-2467813
MAPK1/MAPK3 signaling R-HSA-5684996
Beta-catenin independent WNT signaling R-HSA-3858494
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'on' state R-HSA-5632684
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX3 R-HSA-8878159
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX2 expression and activity R-HSA-8939902
Vpu mediated degradation of CD4 R-HSA-180534
Synthesis of DNA R-HSA-69239
Programmed Cell Death R-HSA-5357801
Neddylation R-HSA-8951664
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin E associated events during G1/S transition R-HSA-69202
ABC-family proteins mediated transport R-HSA-382556
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RNA Polymerase II Transcription R-HSA-73857
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism R-HSA-1430728
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Regulation of RUNX3 expression and activity R-HSA-8941858
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
FCERI mediated NF-kB activation R-HSA-2871837
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
p53-Independent DNA Damage Response R-HSA-69610
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
Apoptosis R-HSA-109581
Mitotic G1 phase and G1/S transition R-HSA-453279
HIV Infection R-HSA-162906
Switching of origins to a post-replicative state R-HSA-69052
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Innate Immune System R-HSA-168249
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of DVL R-HSA-4641258
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RAF/MAP kinase cascade R-HSA-5673001
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
Developmental Biology R-HSA-1266738
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Degradation of GLI2 by the proteasome R-HSA-5610783
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
Neutrophil degranulation R-HSA-6798695
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC transporter disorders R-HSA-5619084
Cellular responses to stress R-HSA-2262752
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Stabilization of p53 R-HSA-69541
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Ub-specific processing proteases R-HSA-5689880
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Orc1 removal from chromatin R-HSA-68949
Immune System R-HSA-168256
Cellular response to hypoxia R-HSA-1234174
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RAS by GAPs R-HSA-5658442
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Regulation of mitotic cell cycle R-HSA-453276
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by NOTCH R-HSA-157118
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of NF-kappaB in B cells R-HSA-1169091
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Degradation of AXIN R-HSA-4641257
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication R-HSA-69306
Host Interactions of HIV factors R-HSA-162909
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by WNT R-HSA-195721
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to hypoxia R-HSA-1234174
PTEN Regulation R-HSA-6807070
UCH proteinases R-HSA-5689603
MAPK family signaling cascades R-HSA-5683057
Cellular response to chemical stress R-HSA-9711123
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Metaphase and Anaphase R-HSA-2555396
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Asymmetric localization of PCP proteins R-HSA-4608870
Class I MHC mediated antigen processing & presentation R-HSA-983169
FCERI mediated NF-kB activation R-HSA-2871837
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of RNA R-HSA-8953854
Cyclin E associated events during G1/S transition R-HSA-69202
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Degradation of GLI2 by the proteasome R-HSA-5610783
PCP/CE pathway R-HSA-4086400
Ub-specific processing proteases R-HSA-5689880
Cell Cycle, Mitotic R-HSA-69278
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stimuli R-HSA-8953897
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RAS by GAPs R-HSA-5658442
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Signaling by Hedgehog R-HSA-5358351
G2/M Transition R-HSA-69275
Metabolism R-HSA-1430728
Hedgehog 'off' state R-HSA-5610787
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Gene expression (Transcription) R-HSA-74160
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Disorders of transmembrane transporters R-HSA-5619115
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Neddylation R-HSA-8951664
Cell Cycle R-HSA-1640170
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Immune System R-HSA-168256
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
Switching of origins to a post-replicative state R-HSA-69052
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S Transition R-HSA-69206
Nervous system development R-HSA-9675108
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional regulation by RUNX2 R-HSA-8878166
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Transition R-HSA-69275
MAPK family signaling cascades R-HSA-5683057
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Metabolism of polyamines R-HSA-351202
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Hedgehog 'on' state R-HSA-5632684
Switching of origins to a post-replicative state R-HSA-69052
Stabilization of p53 R-HSA-69541
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog ligand biogenesis R-HSA-5358346
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Transport of small molecules R-HSA-382551
Cytokine Signaling in Immune system R-HSA-1280215
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
ER-Phagosome pathway R-HSA-1236974
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC-family proteins mediated transport R-HSA-382556
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Neutrophil degranulation R-HSA-6798695
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
Host Interactions of HIV factors R-HSA-162909
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Degradation of AXIN R-HSA-4641257
RNA Polymerase II Transcription R-HSA-73857
Vpu mediated degradation of CD4 R-HSA-180534
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Apoptosis R-HSA-109581
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism R-HSA-1430728
p53-Independent DNA Damage Response R-HSA-69610
Separation of Sister Chromatids R-HSA-2467813
Regulation of RAS by GAPs R-HSA-5658442
PCP/CE pathway R-HSA-4086400
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Mitotic Metaphase and Anaphase R-HSA-2555396
Transcriptional regulation by RUNX3 R-HSA-8878159
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
DNA Replication R-HSA-69306
Antigen processing-Cross presentation R-HSA-1236975
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX2 expression and activity R-HSA-8939902
Downstream TCR signaling R-HSA-202424
Cellular responses to stress R-HSA-2262752
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G1 phase and G1/S transition R-HSA-453279
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCF dependent signaling in response to WNT R-HSA-201681
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH4 R-HSA-9013694
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of PTEN stability and activity R-HSA-8948751
Generic Transcription Pathway R-HSA-212436
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin E associated events during G1/S transition R-HSA-69202

Expression Atlas ENSG00000008018
NCBI gene (formerly Entrezgene) 5689
GeneCards 9537
HGNC Symbol HGNC:9537
MIM gene 602017
MIM morbid 620038
UniProtKB Gene Name P20618
WikiGene 5689
Gene: ADRM1
Ensembl ID : ENSG00000130706
Description: ADRM1 26S proteasome ubiquitin receptor
Gene Synonyms: ARM1,GP110,PSMD16,RPN13
5 APIs:
261 Possible Orthologues:

Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Deubiquitination R-HSA-5688426
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592

Expression Atlas ENSG00000130706
NCBI gene (formerly Entrezgene) 11047
GeneCards 15759
HGNC Symbol HGNC:15759
MIM gene 610650
UniProtKB Gene Name Q16186
WikiGene 11047
Gene: ABL1
Ensembl ID : ENSG00000097007
Description: ABL proto-oncogene 1, non-receptor tyrosine kinase
Gene Synonyms: ABL,C-ABL,JTK7,P150
21 APIs:
204 Possible Orthologues:

Parasite infection R-HSA-9664407
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Homology Directed Repair R-HSA-5693538
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Axon guidance R-HSA-422475
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nervous system development R-HSA-9675108
Parasite infection R-HSA-9664407
Transcriptional regulation by RUNX1 R-HSA-8878171
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Leishmania infection R-HSA-9658195
Innate Immune System R-HSA-168249
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Cell Cycle, Mitotic R-HSA-69278
RHO GTPase Effectors R-HSA-195258
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
DNA Repair R-HSA-73894
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
FCGR3A-mediated phagocytosis R-HSA-9664422
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Disease R-HSA-1643685
Cyclin D associated events in G1 R-HSA-69231
Leishmania phagocytosis R-HSA-9664417
RNA Polymerase II Transcription R-HSA-73857
Myogenesis R-HSA-525793
RUNX2 regulates bone development R-HSA-8941326
Infectious disease R-HSA-5663205
Hemostasis R-HSA-109582
G1 Phase R-HSA-69236
DNA Double Strand Break Response R-HSA-5693606
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
Gene expression (Transcription) R-HSA-74160
Role of ABL in ROBO-SLIT signaling R-HSA-428890
DNA Repair R-HSA-73894
Signaling by Rho GTPases R-HSA-194315
DNA Double-Strand Break Repair R-HSA-5693532
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Leishmania phagocytosis R-HSA-9664417
Transcriptional regulation by RUNX1 R-HSA-8878171
Generic Transcription Pathway R-HSA-212436
DNA Double Strand Break Response R-HSA-5693606
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Cyclin D associated events in G1 R-HSA-69231
Nervous system development R-HSA-9675108
G1 Phase R-HSA-69236
Role of ABL in ROBO-SLIT signaling R-HSA-428890
Immune System R-HSA-168256
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Myogenesis R-HSA-525793
Homology Directed Repair R-HSA-5693538
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX2 R-HSA-8878166
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RUNX2 regulates bone development R-HSA-8941326
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hemostasis R-HSA-109582
FCGR3A-mediated phagocytosis R-HSA-9664422
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RHO GTPase Effectors R-HSA-195258
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RNA Polymerase II Transcription R-HSA-73857
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
DNA Double-Strand Break Repair R-HSA-5693532
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
DNA Double Strand Break Response R-HSA-5693606
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Parasite infection R-HSA-9664407
Transcriptional regulation by RUNX2 R-HSA-8878166
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin D associated events in G1 R-HSA-69231
Cell Cycle, Mitotic R-HSA-69278
Leishmania infection R-HSA-9658195
RUNX2 regulates bone development R-HSA-8941326
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Transcriptional regulation by RUNX1 R-HSA-8878171
FCGR3A-mediated phagocytosis R-HSA-9664422
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Gene expression (Transcription) R-HSA-74160
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
Leishmania phagocytosis R-HSA-9664417
Axon guidance R-HSA-422475
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Homology Directed Repair R-HSA-5693538
Role of ABL in ROBO-SLIT signaling R-HSA-428890
G1 Phase R-HSA-69236
Hemostasis R-HSA-109582
Myogenesis R-HSA-525793
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
RHO GTPase Effectors R-HSA-195258
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Nervous system development R-HSA-9675108
DNA Repair R-HSA-73894
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
RHO GTPase Effectors R-HSA-195258
G1 Phase R-HSA-69236
Cyclin D associated events in G1 R-HSA-69231
RUNX2 regulates osteoblast differentiation R-HSA-8940973
RUNX2 regulates bone development R-HSA-8941326
Hemostasis R-HSA-109582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Signaling by ROBO receptors R-HSA-376176
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
Homology Directed Repair R-HSA-5693538
Myogenesis R-HSA-525793
Parasite infection R-HSA-9664407
Leishmania phagocytosis R-HSA-9664417
RNA Polymerase II Transcription R-HSA-73857
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
FCGR3A-mediated phagocytosis R-HSA-9664422
Cell Cycle, Mitotic R-HSA-69278
DNA Repair R-HSA-73894
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Role of ABL in ROBO-SLIT signaling R-HSA-428890
DNA Double Strand Break Response R-HSA-5693606
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Leishmania infection R-HSA-9658195
Cell Cycle R-HSA-1640170
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Generic Transcription Pathway R-HSA-212436
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
Innate Immune System R-HSA-168249
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Infectious disease R-HSA-5663205
Mitotic G1 phase and G1/S transition R-HSA-453279
RUNX2 regulates bone development R-HSA-8941326
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
FCGR3A-mediated phagocytosis R-HSA-9664422
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Parasite infection R-HSA-9664407
Signaling by ROBO receptors R-HSA-376176
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Leishmania infection R-HSA-9658195
Role of ABL in ROBO-SLIT signaling R-HSA-428890
Cyclin D associated events in G1 R-HSA-69231
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Leishmania phagocytosis R-HSA-9664417
DNA Repair R-HSA-73894
Immune System R-HSA-168256
Developmental Biology R-HSA-1266738
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RUNX2 regulates osteoblast differentiation R-HSA-8940973
DNA Double-Strand Break Repair R-HSA-5693532
Myogenesis R-HSA-525793
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
DNA Double Strand Break Response R-HSA-5693606
Cell Cycle, Mitotic R-HSA-69278
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Axon guidance R-HSA-422475
Hemostasis R-HSA-109582
Homology Directed Repair R-HSA-5693538
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
HDR through Single Strand Annealing (SSA) R-HSA-5685938
G1 Phase R-HSA-69236
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
DNA Double Strand Break Response R-HSA-5693606
Transcriptional regulation by RUNX1 R-HSA-8878171
Leishmania phagocytosis R-HSA-9664417
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Repair R-HSA-73894
FCGR3A-mediated phagocytosis R-HSA-9664422
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Cyclin D associated events in G1 R-HSA-69231
Nervous system development R-HSA-9675108
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by Rho GTPases R-HSA-194315
Factors involved in megakaryocyte development and platelet production R-HSA-983231
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
RHO GTPase Effectors R-HSA-195258
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates bone development R-HSA-8941326
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Myogenesis R-HSA-525793
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signal Transduction R-HSA-162582
Cell Cycle R-HSA-1640170
Developmental Biology R-HSA-1266738
Homology Directed Repair R-HSA-5693538
RNA Polymerase II Transcription R-HSA-73857
Immune System R-HSA-168256
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Parasite infection R-HSA-9664407
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
G1 Phase R-HSA-69236
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Mitotic G1 phase and G1/S transition R-HSA-453279
Leishmania infection R-HSA-9658195
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Role of ABL in ROBO-SLIT signaling R-HSA-428890
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
RHO GTPase Effectors R-HSA-195258
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by Rho GTPases R-HSA-194315
Factors involved in megakaryocyte development and platelet production R-HSA-983231
DNA Double Strand Break Response R-HSA-5693606
Cyclin D associated events in G1 R-HSA-69231
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Parasite infection R-HSA-9664407
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle, Mitotic R-HSA-69278
G1 Phase R-HSA-69236
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Transcriptional regulation by RUNX1 R-HSA-8878171
DNA Double-Strand Break Repair R-HSA-5693532
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Role of ABL in ROBO-SLIT signaling R-HSA-428890
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Nervous system development R-HSA-9675108
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by ROBO receptors R-HSA-376176
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
RUNX2 regulates bone development R-HSA-8941326
FCGR3A-mediated phagocytosis R-HSA-9664422
Homology Directed Repair R-HSA-5693538
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Axon guidance R-HSA-422475
DNA Repair R-HSA-73894
Hemostasis R-HSA-109582
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Innate Immune System R-HSA-168249
Leishmania infection R-HSA-9658195
Myogenesis R-HSA-525793
Leishmania phagocytosis R-HSA-9664417
Mitotic G1 phase and G1/S transition R-HSA-453279
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Myogenesis R-HSA-525793
Developmental Biology R-HSA-1266738
Cyclin D associated events in G1 R-HSA-69231
Role of ABL in ROBO-SLIT signaling R-HSA-428890
Cell Cycle R-HSA-1640170
Hemostasis R-HSA-109582
HDR through Single Strand Annealing (SSA) R-HSA-5685938
DNA Double Strand Break Response R-HSA-5693606
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Innate Immune System R-HSA-168249
Leishmania phagocytosis R-HSA-9664417
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
Leishmania infection R-HSA-9658195
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by ROBO receptors R-HSA-376176
Parasite infection R-HSA-9664407
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional regulation by RUNX2 R-HSA-8878166
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
DNA Repair R-HSA-73894
FCGR3A-mediated phagocytosis R-HSA-9664422
Axon guidance R-HSA-422475
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RHO GTPase Effectors R-HSA-195258
Infectious disease R-HSA-5663205
G1 Phase R-HSA-69236
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
RUNX2 regulates bone development R-HSA-8941326
Homology Directed Repair R-HSA-5693538
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
DNA Repair R-HSA-73894
Leishmania phagocytosis R-HSA-9664417
Innate Immune System R-HSA-168249
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Leishmania infection R-HSA-9658195
Hemostasis R-HSA-109582
Myogenesis R-HSA-525793
FCGR3A-mediated phagocytosis R-HSA-9664422
RHO GTPase Effectors R-HSA-195258
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
Immune System R-HSA-168256
DNA Double-Strand Break Repair R-HSA-5693532
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
G1 Phase R-HSA-69236
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Infectious disease R-HSA-5663205
RUNX2 regulates bone development R-HSA-8941326
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Homology Directed Repair R-HSA-5693538
Signaling by Rho GTPases R-HSA-194315
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Parasite infection R-HSA-9664407
Axon guidance R-HSA-422475
Disease R-HSA-1643685
DNA Double Strand Break Response R-HSA-5693606
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cyclin D associated events in G1 R-HSA-69231
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Role of ABL in ROBO-SLIT signaling R-HSA-428890
Generic Transcription Pathway R-HSA-212436
Signaling by Rho GTPases R-HSA-194315
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX2 regulates bone development R-HSA-8941326
Innate Immune System R-HSA-168249
RHO GTPase Effectors R-HSA-195258
Infectious disease R-HSA-5663205
Signaling by ROBO receptors R-HSA-376176
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Myogenesis R-HSA-525793
Mitotic G1 phase and G1/S transition R-HSA-453279
Leishmania infection R-HSA-9658195
DNA Double Strand Break Response R-HSA-5693606
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Axon guidance R-HSA-422475
Immune System R-HSA-168256
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
DNA Repair R-HSA-73894
RUNX2 regulates osteoblast differentiation R-HSA-8940973
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
G1 Phase R-HSA-69236
Cell Cycle, Mitotic R-HSA-69278
Hemostasis R-HSA-109582
HDR through Single Strand Annealing (SSA) R-HSA-5685938
Cyclin D associated events in G1 R-HSA-69231
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Leishmania phagocytosis R-HSA-9664417
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Parasite infection R-HSA-9664407
FCGR3A-mediated phagocytosis R-HSA-9664422
Role of ABL in ROBO-SLIT signaling R-HSA-428890
Homology Directed Repair R-HSA-5693538

Expression Atlas ENSG00000097007
LRG display in Ensembl gene LRG_769
NCBI gene (formerly Entrezgene) 25
GeneCards 76
HGNC Symbol HGNC:76
MIM gene 189980
MIM morbid 617602
UniProtKB Gene Name R4GRW0
WikiGene 25
Gene: NFKB1
Ensembl ID : ENSG00000109320
Description: nuclear factor kappa B subunit 1
Gene Synonyms: KBF1,NF-KAPPAB,NF-KB1,NFKAPPAB,NFKB-P50,P105,P50
1 APIs:
204 Possible Orthologues:

SARS-CoV-1 Infection R-HSA-9678108
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
HCMV Early Events R-HSA-9609690
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
TRAF6 mediated NF-kB activation R-HSA-933542
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
C-type lectin receptors (CLRs) R-HSA-5621481
p75 NTR receptor-mediated signalling R-HSA-193704
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Diseases of Immune System R-HSA-5260271
SARS-CoV Infections R-HSA-9679506
PKMTs methylate histone lysines R-HSA-3214841
Cell recruitment (pro-inflammatory response) R-HSA-9664424
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Regulated proteolysis of p75NTR R-HSA-193692
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Interleukin-17 signaling R-HSA-448424
Cellular responses to stress R-HSA-2262752
p75NTR signals via NF-kB R-HSA-193639
Innate Immune System R-HSA-168249
MyD88 dependent cascade initiated on endosome R-HSA-975155
IkBA variant leads to EDA-ID R-HSA-5603029
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular Senescence R-HSA-2559583
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Interleukin-1 family signaling R-HSA-446652
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Interleukin-1 processing R-HSA-448706
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP kinase activation R-HSA-450294
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Death Receptor Signaling R-HSA-73887
Transcriptional Regulation by VENTX R-HSA-8853884
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Inflammasomes R-HSA-622312
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin organization R-HSA-4839726
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
HCMV Infection R-HSA-9609646
Infectious disease R-HSA-5663205
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
CLEC7A/inflammasome pathway R-HSA-5660668
Leishmania infection R-HSA-9658195
CD209 (DC-SIGN) signaling R-HSA-5621575
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases associated with the TLR signaling cascade R-HSA-5602358
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Neutrophil degranulation R-HSA-6798695
SARS-CoV-1-host interactions R-HSA-9692914
TCR signaling R-HSA-202403
Chromatin modifying enzymes R-HSA-3247509
The NLRP3 inflammasome R-HSA-844456
MyD88-independent TLR4 cascade R-HSA-166166
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Interleukin-1 signaling R-HSA-9020702
Toll-like Receptor Cascades R-HSA-168898
SARS-CoV-1 Infection R-HSA-9678108
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cellular responses to stress R-HSA-2262752
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Neutrophil degranulation R-HSA-6798695
Leishmania infection R-HSA-9658195
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Gene expression (Transcription) R-HSA-74160
Diseases of Immune System R-HSA-5260271
p75NTR signals via NF-kB R-HSA-193639
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular Senescence R-HSA-2559583
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
PKMTs methylate histone lysines R-HSA-3214841
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Chromatin organization R-HSA-4839726
Infectious disease R-HSA-5663205
Interleukin-17 signaling R-HSA-448424
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
TRAF6 mediated NF-kB activation R-HSA-933542
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Immune System R-HSA-168256
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Chromatin modifying enzymes R-HSA-3247509
NF-kB is activated and signals survival R-HSA-209560
HCMV Early Events R-HSA-9609690
Interleukin-1 processing R-HSA-448706
HCMV Infection R-HSA-9609646
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
Inflammasomes R-HSA-622312
CLEC7A/inflammasome pathway R-HSA-5660668
Generic Transcription Pathway R-HSA-212436
p75 NTR receptor-mediated signalling R-HSA-193704
Transcriptional Regulation by VENTX R-HSA-8853884
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
Cell recruitment (pro-inflammatory response) R-HSA-9664424
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The NLRP3 inflammasome R-HSA-844456
Regulated proteolysis of p75NTR R-HSA-193692
MyD88 dependent cascade initiated on endosome R-HSA-975155
IkBA variant leads to EDA-ID R-HSA-5603029
Activation of NF-kappaB in B cells R-HSA-1169091
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Death Receptor Signaling R-HSA-73887
Diseases associated with the TLR signaling cascade R-HSA-5602358
TCR signaling R-HSA-202403
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RNA Polymerase II Transcription R-HSA-73857
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
SARS-CoV Infections R-HSA-9679506
MAP kinase activation R-HSA-450294
Neutrophil degranulation R-HSA-6798695
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
MyD88 cascade initiated on plasma membrane R-HSA-975871
MAP kinase activation R-HSA-450294
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Generic Transcription Pathway R-HSA-212436
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 processing R-HSA-448706
CLEC7A/inflammasome pathway R-HSA-5660668
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
PKMTs methylate histone lysines R-HSA-3214841
p75 NTR receptor-mediated signalling R-HSA-193704
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
NF-kB is activated and signals survival R-HSA-209560
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Downstream TCR signaling R-HSA-202424
Chromatin modifying enzymes R-HSA-3247509
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
The NLRP3 inflammasome R-HSA-844456
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Activation of NF-kappaB in B cells R-HSA-1169091
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
C-type lectin receptors (CLRs) R-HSA-5621481
Transcriptional Regulation by VENTX R-HSA-8853884
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Purinergic signaling in leishmaniasis infection R-HSA-9660826
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated NF-kB activation R-HSA-2871837
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Death Receptor Signaling R-HSA-73887
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Regulated proteolysis of p75NTR R-HSA-193692
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
HCMV Infection R-HSA-9609646
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
TRAF6 mediated NF-kB activation R-HSA-933542
Leishmania infection R-HSA-9658195
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular responses to stimuli R-HSA-8953897
Inflammasomes R-HSA-622312
Gene expression (Transcription) R-HSA-74160
Toll-like Receptor Cascades R-HSA-168898
p75NTR signals via NF-kB R-HSA-193639
Signaling by Interleukins R-HSA-449147
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-17 signaling R-HSA-448424
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Chromatin organization R-HSA-4839726
Interleukin-1 signaling R-HSA-9020702
HCMV Early Events R-HSA-9609690
Diseases associated with the TLR signaling cascade R-HSA-5602358
IkBA variant leads to EDA-ID R-HSA-5603029
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV Infections R-HSA-9679506
RNA Polymerase II Transcription R-HSA-73857
Cellular Senescence R-HSA-2559583
Diseases of Immune System R-HSA-5260271
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
SARS-CoV-1 Infection R-HSA-9678108
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
MyD88 dependent cascade initiated on endosome R-HSA-975155
Diseases associated with the TLR signaling cascade R-HSA-5602358
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-17 signaling R-HSA-448424
Interleukin-1 processing R-HSA-448706
Inflammasomes R-HSA-622312
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCERI mediated NF-kB activation R-HSA-2871837
p75NTR signals via NF-kB R-HSA-193639
Cellular responses to stimuli R-HSA-8953897
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Diseases of Immune System R-HSA-5260271
Regulated proteolysis of p75NTR R-HSA-193692
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Cellular responses to stress R-HSA-2262752
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
IkBA variant leads to EDA-ID R-HSA-5603029
SARS-CoV Infections R-HSA-9679506
Activation of NF-kappaB in B cells R-HSA-1169091
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
HCMV Early Events R-HSA-9609690
Leishmania infection R-HSA-9658195
Chromatin organization R-HSA-4839726
PKMTs methylate histone lysines R-HSA-3214841
Neutrophil degranulation R-HSA-6798695
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
SARS-CoV-1 Infection R-HSA-9678108
TRAF6 mediated NF-kB activation R-HSA-933542
Transcriptional Regulation by VENTX R-HSA-8853884
TCR signaling R-HSA-202403
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Chromatin modifying enzymes R-HSA-3247509
Signaling by Interleukins R-HSA-449147
MyD88 cascade initiated on plasma membrane R-HSA-975871
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
CLEC7A/inflammasome pathway R-HSA-5660668
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Death Receptor Signaling R-HSA-73887
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Infectious disease R-HSA-5663205
HCMV Infection R-HSA-9609646
Toll-like Receptor Cascades R-HSA-168898
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Disease R-HSA-1643685
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
NF-kB is activated and signals survival R-HSA-209560
Gene expression (Transcription) R-HSA-74160
The NLRP3 inflammasome R-HSA-844456
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
The NLRP3 inflammasome R-HSA-844456
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated NF-kB activation R-HSA-933542
Neutrophil degranulation R-HSA-6798695
Developmental Biology R-HSA-1266738
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
SARS-CoV-1-host interactions R-HSA-9692914
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TCR signaling R-HSA-202403
PKMTs methylate histone lysines R-HSA-3214841
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Generic Transcription Pathway R-HSA-212436
p75NTR signals via NF-kB R-HSA-193639
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Diseases associated with the TLR signaling cascade R-HSA-5602358
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stress R-HSA-2262752
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
IkBA variant leads to EDA-ID R-HSA-5603029
FCERI mediated NF-kB activation R-HSA-2871837
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Chromatin modifying enzymes R-HSA-3247509
Inflammasomes R-HSA-622312
Death Receptor Signaling R-HSA-73887
Leishmania infection R-HSA-9658195
SARS-CoV-1 Infection R-HSA-9678108
Disease R-HSA-1643685
Interleukin-17 signaling R-HSA-448424
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Regulated proteolysis of p75NTR R-HSA-193692
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
Purinergic signaling in leishmaniasis infection R-HSA-9660826
CLEC7A/inflammasome pathway R-HSA-5660668
HCMV Infection R-HSA-9609646
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Diseases of Immune System R-HSA-5260271
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Interleukin-1 family signaling R-HSA-446652
Chromatin organization R-HSA-4839726
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Activation of NF-kappaB in B cells R-HSA-1169091
SARS-CoV Infections R-HSA-9679506
Cytokine Signaling in Immune system R-HSA-1280215
CD209 (DC-SIGN) signaling R-HSA-5621575
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
HCMV Early Events R-HSA-9609690
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
C-type lectin receptors (CLRs) R-HSA-5621481
Cell recruitment (pro-inflammatory response) R-HSA-9664424
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Transcriptional Regulation by VENTX R-HSA-8853884
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Diseases associated with the TLR signaling cascade R-HSA-5602358
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
MyD88-independent TLR4 cascade R-HSA-166166
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Death Receptor Signaling R-HSA-73887
Interleukin-1 family signaling R-HSA-446652
SARS-CoV-1-host interactions R-HSA-9692914
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Developmental Biology R-HSA-1266738
Cytokine Signaling in Immune system R-HSA-1280215
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Downstream TCR signaling R-HSA-202424
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Signaling by Interleukins R-HSA-449147
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
HCMV Early Events R-HSA-9609690
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
IkBA variant leads to EDA-ID R-HSA-5603029
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Inflammasomes R-HSA-622312
CLEC7A/inflammasome pathway R-HSA-5660668
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll-like Receptor Cascades R-HSA-168898
NF-kB is activated and signals survival R-HSA-209560
The NLRP3 inflammasome R-HSA-844456
TCR signaling R-HSA-202403
Transcriptional Regulation by VENTX R-HSA-8853884
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Signal Transduction R-HSA-162582
CLEC7A (Dectin-1) signaling R-HSA-5607764
CD209 (DC-SIGN) signaling R-HSA-5621575
PKMTs methylate histone lysines R-HSA-3214841
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Leishmania infection R-HSA-9658195
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP kinase activation R-HSA-450294
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
SARS-CoV Infections R-HSA-9679506
Regulated proteolysis of p75NTR R-HSA-193692
Infectious disease R-HSA-5663205
p75NTR signals via NF-kB R-HSA-193639
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 cascade initiated on plasma membrane R-HSA-975871
SARS-CoV-1 Infection R-HSA-9678108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Chromatin organization R-HSA-4839726
Interleukin-1 processing R-HSA-448706
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
C-type lectin receptors (CLRs) R-HSA-5621481
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
HCMV Infection R-HSA-9609646
p75 NTR receptor-mediated signalling R-HSA-193704
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin modifying enzymes R-HSA-3247509
Diseases of Immune System R-HSA-5260271
Infectious disease R-HSA-5663205
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
CLEC7A/inflammasome pathway R-HSA-5660668
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Purinergic signaling in leishmaniasis infection R-HSA-9660826
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
Cellular Senescence R-HSA-2559583
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Chromatin organization R-HSA-4839726
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
SARS-CoV-1 Infection R-HSA-9678108
C-type lectin receptors (CLRs) R-HSA-5621481
Interleukin-1 processing R-HSA-448706
Innate Immune System R-HSA-168249
Inflammasomes R-HSA-622312
Generic Transcription Pathway R-HSA-212436
p75 NTR receptor-mediated signalling R-HSA-193704
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
CD209 (DC-SIGN) signaling R-HSA-5621575
Cellular responses to stress R-HSA-2262752
Regulated proteolysis of p75NTR R-HSA-193692
Chromatin modifying enzymes R-HSA-3247509
Leishmania infection R-HSA-9658195
Diseases associated with the TLR signaling cascade R-HSA-5602358
MAP kinase activation R-HSA-450294
Adaptive Immune System R-HSA-1280218
IkBA variant leads to EDA-ID R-HSA-5603029
Developmental Biology R-HSA-1266738
Death Receptor Signaling R-HSA-73887
p75NTR signals via NF-kB R-HSA-193639
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of Immune System R-HSA-5260271
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PKMTs methylate histone lysines R-HSA-3214841
SARS-CoV-1-host interactions R-HSA-9692914
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
The NLRP3 inflammasome R-HSA-844456
HCMV Early Events R-HSA-9609690
Signaling by Interleukins R-HSA-449147
TCR signaling R-HSA-202403
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Transcriptional Regulation by VENTX R-HSA-8853884
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Toll-like Receptor Cascades R-HSA-168898
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
NF-kB is activated and signals survival R-HSA-209560
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cell recruitment (pro-inflammatory response) R-HSA-9664424
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated NF-kB activation R-HSA-933542
Cellular responses to stimuli R-HSA-8953897
HCMV Infection R-HSA-9609646
Neutrophil degranulation R-HSA-6798695
Interleukin-17 signaling R-HSA-448424
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated NF-kB activation R-HSA-2871837
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
HCMV Early Events R-HSA-9609690
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Transcriptional Regulation by VENTX R-HSA-8853884
Inflammasomes R-HSA-622312
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 processing R-HSA-448706
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
Activation of NF-kappaB in B cells R-HSA-1169091
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Neutrophil degranulation R-HSA-6798695
Diseases associated with the TLR signaling cascade R-HSA-5602358
TCR signaling R-HSA-202403
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
HCMV Infection R-HSA-9609646
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
p75NTR signals via NF-kB R-HSA-193639
Infectious disease R-HSA-5663205
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Downstream TCR signaling R-HSA-202424
SARS-CoV-1 Infection R-HSA-9678108
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin organization R-HSA-4839726
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Diseases of Immune System R-HSA-5260271
SARS-CoV-1-host interactions R-HSA-9692914
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
TRAF6 mediated NF-kB activation R-HSA-933542
MAP kinase activation R-HSA-450294
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulated proteolysis of p75NTR R-HSA-193692
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
CD209 (DC-SIGN) signaling R-HSA-5621575
Signaling by Interleukins R-HSA-449147
Chromatin modifying enzymes R-HSA-3247509
Leishmania infection R-HSA-9658195
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Cellular responses to stress R-HSA-2262752
MyD88-independent TLR4 cascade R-HSA-166166
Cell recruitment (pro-inflammatory response) R-HSA-9664424
p75 NTR receptor-mediated signalling R-HSA-193704
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-17 signaling R-HSA-448424
CLEC7A/inflammasome pathway R-HSA-5660668
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
The NLRP3 inflammasome R-HSA-844456
PKMTs methylate histone lysines R-HSA-3214841
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
Disease R-HSA-1643685
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Interleukin-1 family signaling R-HSA-446652
Interleukin-1 signaling R-HSA-9020702
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
SARS-CoV-1 Infection R-HSA-9678108
Purinergic signaling in leishmaniasis infection R-HSA-9660826
MyD88 cascade initiated on plasma membrane R-HSA-975871
Leishmania infection R-HSA-9658195
IkBA variant leads to EDA-ID R-HSA-5603029
p75 NTR receptor-mediated signalling R-HSA-193704
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 processing R-HSA-448706
HCMV Infection R-HSA-9609646
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stress R-HSA-2262752
MyD88 dependent cascade initiated on endosome R-HSA-975155
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Interleukin-17 signaling R-HSA-448424
CLEC7A/inflammasome pathway R-HSA-5660668
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Chromatin modifying enzymes R-HSA-3247509
PKMTs methylate histone lysines R-HSA-3214841
Death Receptor Signaling R-HSA-73887
CD209 (DC-SIGN) signaling R-HSA-5621575
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Inflammasomes R-HSA-622312
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin organization R-HSA-4839726
Neutrophil degranulation R-HSA-6798695
Developmental Biology R-HSA-1266738
The NLRP3 inflammasome R-HSA-844456
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Gene expression (Transcription) R-HSA-74160
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAP kinase activation R-HSA-450294
Downstream TCR signaling R-HSA-202424
TRAF6 mediated NF-kB activation R-HSA-933542
p75NTR signals via NF-kB R-HSA-193639
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Cell recruitment (pro-inflammatory response) R-HSA-9664424
NF-kB is activated and signals survival R-HSA-209560
Cellular Senescence R-HSA-2559583
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
Infectious disease R-HSA-5663205
SARS-CoV-1-host interactions R-HSA-9692914
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Transcriptional Regulation by VENTX R-HSA-8853884
HCMV Early Events R-HSA-9609690
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Regulated proteolysis of p75NTR R-HSA-193692
Activation of NF-kappaB in B cells R-HSA-1169091
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Diseases of Immune System R-HSA-5260271
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Generic Transcription Pathway R-HSA-212436
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Diseases associated with the TLR signaling cascade R-HSA-5602358
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061

Expression Atlas ENSG00000109320
LRG display in Ensembl gene LRG_1316
NCBI gene (formerly Entrezgene) 4790
GeneCards 7794
HGNC Symbol HGNC:7794
MIM gene 164011
MIM morbid 616576
UniProtKB Gene Name P19838
WikiGene 4790
Gene: PSMB11
Ensembl ID : ENSG00000222028
Description: proteasome subunit beta 11
Gene Synonyms: BETA5T
6 APIs:
228 Possible Orthologues:

Cytokine Signaling in Immune system R-HSA-1280215
TCR signaling R-HSA-202403
Signaling by Interleukins R-HSA-449147
Programmed Cell Death R-HSA-5357801
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism R-HSA-1430728
ER-Phagosome pathway R-HSA-1236974
ABC transporter disorders R-HSA-5619084
S Phase R-HSA-69242
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stimuli R-HSA-8953897
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX2 R-HSA-8878166
Post-translational protein modification R-HSA-597592
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Mitotic Anaphase R-HSA-68882
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
HIV Infection R-HSA-162906
Hh mutants are degraded by ERAD R-HSA-5362768
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Metabolism of RNA R-HSA-8953854
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing-Cross presentation R-HSA-1236975
Signaling by WNT R-HSA-195721
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Regulation of RUNX2 expression and activity R-HSA-8939902
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Checkpoints R-HSA-69481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of beta-catenin by the destruction complex R-HSA-195253
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S DNA Damage Checkpoints R-HSA-69615
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular response to hypoxia R-HSA-1234174
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Metabolism of RNA R-HSA-8953854
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Adaptive Immune System R-HSA-1280218
Infectious disease R-HSA-5663205
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Regulation of expression of SLITs and ROBOs R-HSA-9010553
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Mitotic G2-G2/M phases R-HSA-453274
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Hedgehog ligand biogenesis R-HSA-5358346
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
ABC-family proteins mediated transport R-HSA-382556
MAPK family signaling cascades R-HSA-5683057
Post-translational protein modification R-HSA-597592
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Synthesis of DNA R-HSA-69239
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX1 R-HSA-8878171
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stimuli R-HSA-8953897
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of amino acids and derivatives R-HSA-71291
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Deubiquitination R-HSA-5688426
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream TCR signaling R-HSA-202424
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
Interleukin-1 family signaling R-HSA-446652
Regulation of RAS by GAPs R-HSA-5658442
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Axon guidance R-HSA-422475
PIP3 activates AKT signaling R-HSA-1257604
Activation of NF-kappaB in B cells R-HSA-1169091
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
ABC transporter disorders R-HSA-5619084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Hh mutants abrogate ligand secretion R-HSA-5387390
ABC-family proteins mediated transport R-HSA-382556
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Axon guidance R-HSA-422475
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Stabilization of p53 R-HSA-69541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Deubiquitination R-HSA-5688426
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Developmental Biology R-HSA-1266738
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Switching of origins to a post-replicative state R-HSA-69052
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mitotic cell cycle R-HSA-453276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by WNT R-HSA-195721
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
Cellular response to chemical stress R-HSA-9711123
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by ROBO receptors R-HSA-376176
Orc1 removal from chromatin R-HSA-68949
ABC transporter disorders R-HSA-5619084
Regulation of RUNX2 expression and activity R-HSA-8939902
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Infectious disease R-HSA-5663205
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
UCH proteinases R-HSA-5689603
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
PTEN Regulation R-HSA-6807070
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX2 R-HSA-8878166
Disease R-HSA-1643685
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Neddylation R-HSA-8951664
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Cellular response to hypoxia R-HSA-1234174
KEAP1-NFE2L2 pathway R-HSA-9755511
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 family signaling R-HSA-446652
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
Orc1 removal from chromatin R-HSA-68949
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by ROBO receptors R-HSA-376176
Regulation of RUNX2 expression and activity R-HSA-8939902
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Mitotic G2-G2/M phases R-HSA-453274
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication R-HSA-69306
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Apoptosis R-HSA-109581
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
UCH proteinases R-HSA-5689603
Class I MHC mediated antigen processing & presentation R-HSA-983169
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular responses to stress R-HSA-2262752
Synthesis of DNA R-HSA-69239
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective CFTR causes cystic fibrosis R-HSA-5678895
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
TCR signaling R-HSA-202403
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Immune System R-HSA-168256
Signaling by Hedgehog R-HSA-5358351
RAF/MAP kinase cascade R-HSA-5673001
Post-translational protein modification R-HSA-597592
Metabolism of RNA R-HSA-8953854
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Disease R-HSA-1643685
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Cell Cycle, Mitotic R-HSA-69278
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Apoptosis R-HSA-109581
ER-Phagosome pathway R-HSA-1236974
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
UCH proteinases R-HSA-5689603
S Phase R-HSA-69242
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
Transport of small molecules R-HSA-382551
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PCP/CE pathway R-HSA-4086400
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Infectious disease R-HSA-5663205
Degradation of AXIN R-HSA-4641257
ABC-family proteins mediated transport R-HSA-382556
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Programmed Cell Death R-HSA-5357801
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Ub-specific processing proteases R-HSA-5689880
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
G2/M Transition R-HSA-69275
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Cell Cycle R-HSA-1640170
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic Metaphase and Anaphase R-HSA-2555396
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Programmed Cell Death R-HSA-5357801
RAF/MAP kinase cascade R-HSA-5673001
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
C-type lectin receptors (CLRs) R-HSA-5621481
Signal Transduction R-HSA-162582
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
Gene expression (Transcription) R-HSA-74160
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of RNA R-HSA-8953854
Degradation of DVL R-HSA-4641258
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
Intracellular signaling by second messengers R-HSA-9006925
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TCR signaling R-HSA-202403
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PCP/CE pathway R-HSA-4086400
Degradation of GLI2 by the proteasome R-HSA-5610783
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
Hh mutants abrogate ligand secretion R-HSA-5387390
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of AXIN R-HSA-4641257
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Signaling by ROBO receptors R-HSA-376176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Innate Immune System R-HSA-168249
Degradation of beta-catenin by the destruction complex R-HSA-195253
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle Checkpoints R-HSA-69620
Cellular response to hypoxia R-HSA-1234174
Deubiquitination R-HSA-5688426
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Neddylation R-HSA-8951664
KEAP1-NFE2L2 pathway R-HSA-9755511
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK family signaling cascades R-HSA-5683057
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
HIV Infection R-HSA-162906
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'off' state R-HSA-5610787
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Separation of Sister Chromatids R-HSA-2467813
Host Interactions of HIV factors R-HSA-162909
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Disorders of transmembrane transporters R-HSA-5619115
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
RNA Polymerase II Transcription R-HSA-73857
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RAS by GAPs R-HSA-5658442
Adaptive Immune System R-HSA-1280218
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cellular responses to stimuli R-HSA-8953897
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Gene expression (Transcription) R-HSA-74160
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Stabilization of p53 R-HSA-69541
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Mitotic Metaphase and Anaphase R-HSA-2555396
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
S Phase R-HSA-69242
Apoptosis R-HSA-109581
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cell Cycle Checkpoints R-HSA-69620
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of Apoptosis R-HSA-169911
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Programmed Cell Death R-HSA-5357801
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX1 R-HSA-8878171
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
Cellular response to hypoxia R-HSA-1234174
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Axon guidance R-HSA-422475
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of GLI1 by the proteasome R-HSA-5610780
Degradation of GLI2 by the proteasome R-HSA-5610783
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of amino acids and derivatives R-HSA-71291
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
Signaling by ROBO receptors R-HSA-376176
Signaling by WNT R-HSA-195721
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'on' state R-HSA-5632684
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of DVL R-HSA-4641258
Metabolism R-HSA-1430728
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular responses to stress R-HSA-2262752
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
Gene expression (Transcription) R-HSA-74160
Apoptosis R-HSA-109581
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Programmed Cell Death R-HSA-5357801
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Switching of origins to a post-replicative state R-HSA-69052
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Switching of origins to a post-replicative state R-HSA-69052
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
Regulation of Apoptosis R-HSA-169911
Defective CFTR causes cystic fibrosis R-HSA-5678895
UCH proteinases R-HSA-5689603
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Adaptive Immune System R-HSA-1280218
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Stabilization of p53 R-HSA-69541
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Regulation of RAS by GAPs R-HSA-5658442
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Interleukins R-HSA-449147
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nervous system development R-HSA-9675108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Metabolism R-HSA-1430728
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Class I MHC mediated antigen processing & presentation R-HSA-983169
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
Programmed Cell Death R-HSA-5357801
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S DNA Damage Checkpoints R-HSA-69615
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Disorders of transmembrane transporters R-HSA-5619115
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by Hedgehog R-HSA-5358351
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
Signal Transduction R-HSA-162582
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Axon guidance R-HSA-422475
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Hedgehog ligand biogenesis R-HSA-5358346
Cellular response to chemical stress R-HSA-9711123
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Developmental Biology R-HSA-1266738
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
HIV Infection R-HSA-162906
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Generic Transcription Pathway R-HSA-212436
Hh mutants are degraded by ERAD R-HSA-5362768

Expression Atlas ENSG00000222028
NCBI gene (formerly Entrezgene) 122706
GeneCards 31963
HGNC Symbol HGNC:31963
MIM gene 611137
UniProtKB Gene Name A5LHX3
WikiGene 122706
Gene: PSMA8
Ensembl ID : ENSG00000154611
Description: proteasome 20S subunit alpha 8
Gene Synonyms: MGC26605,PSMA7L
6 APIs:
197 Possible Orthologues:

S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
FCERI mediated NF-kB activation R-HSA-2871837
Cellular response to hypoxia R-HSA-1234174
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mitotic cell cycle R-HSA-453276
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Deubiquitination R-HSA-5688426
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic Anaphase R-HSA-68882
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ABC-family proteins mediated transport R-HSA-382556
Cytokine Signaling in Immune system R-HSA-1280215
Transport of small molecules R-HSA-382551
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of polyamines R-HSA-351202
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MAPK family signaling cascades R-HSA-5683057
Hh mutants abrogate ligand secretion R-HSA-5387390
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Immune System R-HSA-168256
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX2 R-HSA-8878166
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
G2/M Checkpoints R-HSA-69481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Interleukins R-HSA-449147
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
MAPK1/MAPK3 signaling R-HSA-5684996
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Downstream TCR signaling R-HSA-202424
Ub-specific processing proteases R-HSA-5689880
Signaling by ROBO receptors R-HSA-376176
Disease R-HSA-1643685
Metabolism of polyamines R-HSA-351202
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Synthesis of DNA R-HSA-69239
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stress R-HSA-2262752
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by Interleukins R-HSA-449147
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Metaphase and Anaphase R-HSA-2555396
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic G2-G2/M phases R-HSA-453274
Innate Immune System R-HSA-168249
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by WNT R-HSA-195721
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
Interleukin-1 signaling R-HSA-9020702
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to hypoxia R-HSA-1234174
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Replication R-HSA-69306
ABC-family proteins mediated transport R-HSA-382556
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disorders of transmembrane transporters R-HSA-5619115
Hh mutants abrogate ligand secretion R-HSA-5387390
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Stabilization of p53 R-HSA-69541
Degradation of AXIN R-HSA-4641257
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX1 R-HSA-8878171
Apoptosis R-HSA-109581
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
ER-Phagosome pathway R-HSA-1236974
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TCF dependent signaling in response to WNT R-HSA-201681
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK6/MAPK4 signaling R-HSA-5687128
HIV Infection R-HSA-162906
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of Apoptosis R-HSA-169911
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Hedgehog 'on' state R-HSA-5632684
Hedgehog ligand biogenesis R-HSA-5358346
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Adaptive Immune System R-HSA-1280218
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
Asymmetric localization of PCP proteins R-HSA-4608870
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by WNT R-HSA-195721
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog 'off' state R-HSA-5610787
Metabolism of proteins R-HSA-392499
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by ROBO receptors R-HSA-376176
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Dependent G1 DNA Damage Response R-HSA-69563
G2/M Checkpoints R-HSA-69481
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Cellular responses to stress R-HSA-2262752
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Deubiquitination R-HSA-5688426
MAPK1/MAPK3 signaling R-HSA-5684996
Vif-mediated degradation of APOBEC3G R-HSA-180585
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic Anaphase R-HSA-68882
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX2 expression and activity R-HSA-8939902
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Infectious disease R-HSA-5663205
Separation of Sister Chromatids R-HSA-2467813
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle R-HSA-1640170
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Intracellular signaling by second messengers R-HSA-9006925
G2/M Transition R-HSA-69275
Regulation of PTEN stability and activity R-HSA-8948751
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of RAS by GAPs R-HSA-5658442
PIP3 activates AKT signaling R-HSA-1257604
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC-family proteins mediated transport R-HSA-382556
Hedgehog ligand biogenesis R-HSA-5358346
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Stabilization of p53 R-HSA-69541
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'on' state R-HSA-5632684
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Axon guidance R-HSA-422475
Switching of origins to a post-replicative state R-HSA-69052
Signal Transduction R-HSA-162582
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ub-specific processing proteases R-HSA-5689880
ER-Phagosome pathway R-HSA-1236974
Cell Cycle Checkpoints R-HSA-69620
Vpu mediated degradation of CD4 R-HSA-180534
RAF/MAP kinase cascade R-HSA-5673001
TCR signaling R-HSA-202403
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
Orc1 removal from chromatin R-HSA-68949
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCF dependent signaling in response to WNT R-HSA-201681
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
ER-Phagosome pathway R-HSA-1236974
Adaptive Immune System R-HSA-1280218
Antigen processing-Cross presentation R-HSA-1236975
Beta-catenin independent WNT signaling R-HSA-3858494
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Apoptosis R-HSA-109581
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'off' state R-HSA-5610787
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
MAPK1/MAPK3 signaling R-HSA-5684996
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to chemical stress R-HSA-9711123
Metabolism of polyamines R-HSA-351202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signal Transduction R-HSA-162582
Downstream TCR signaling R-HSA-202424
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Degradation of AXIN R-HSA-4641257
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Transport of small molecules R-HSA-382551
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Innate Immune System R-HSA-168249
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cytokine Signaling in Immune system R-HSA-1280215
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of DVL R-HSA-4641258
Degradation of beta-catenin by the destruction complex R-HSA-195253
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Defective CFTR causes cystic fibrosis R-HSA-5678895
Interleukin-1 signaling R-HSA-9020702
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Separation of Sister Chromatids R-HSA-2467813
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism R-HSA-1430728
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Developmental Biology R-HSA-1266738
Cellular response to hypoxia R-HSA-1234174
Regulation of PTEN stability and activity R-HSA-8948751
Degradation of GLI2 by the proteasome R-HSA-5610783
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
M Phase R-HSA-68886
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of amino acids and derivatives R-HSA-71291
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Cell Cycle Checkpoints R-HSA-69620
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX2 R-HSA-8878166
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
M Phase R-HSA-68886
Infectious disease R-HSA-5663205
Degradation of GLI2 by the proteasome R-HSA-5610783
Separation of Sister Chromatids R-HSA-2467813
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by ROBO receptors R-HSA-376176
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Signaling by Interleukins R-HSA-449147
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G2-G2/M phases R-HSA-453274
Class I MHC mediated antigen processing & presentation R-HSA-983169
G1/S DNA Damage Checkpoints R-HSA-69615
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic Anaphase R-HSA-68882
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
G2/M Checkpoints R-HSA-69481
Apoptosis R-HSA-109581
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Antigen processing-Cross presentation R-HSA-1236975
Interleukin-1 family signaling R-HSA-446652
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cytokine Signaling in Immune system R-HSA-1280215
C-type lectin receptors (CLRs) R-HSA-5621481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
RAF/MAP kinase cascade R-HSA-5673001
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
ABC transporter disorders R-HSA-5619084
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
Metabolism R-HSA-1430728
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RAS by GAPs R-HSA-5658442
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Generic Transcription Pathway R-HSA-212436
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Separation of Sister Chromatids R-HSA-2467813
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Ub-specific processing proteases R-HSA-5689880
Deubiquitination R-HSA-5688426
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of mitotic cell cycle R-HSA-453276
Downstream TCR signaling R-HSA-202424
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Checkpoints R-HSA-69481
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
Cell Cycle, Mitotic R-HSA-69278
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
NIK-->noncanonical NF-kB signaling R-HSA-5676590
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle R-HSA-1640170
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hh mutants abrogate ligand secretion R-HSA-5387390
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'on' state R-HSA-5632684
Vpu mediated degradation of CD4 R-HSA-180534
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
Hh mutants are degraded by ERAD R-HSA-5362768
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
Metabolism of amino acids and derivatives R-HSA-71291
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
HIV Infection R-HSA-162906
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mitotic cell cycle R-HSA-453276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Innate Immune System R-HSA-168249
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent DNA Damage Response R-HSA-69610
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Degradation of AXIN R-HSA-4641257
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants abrogate ligand secretion R-HSA-5387390
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Degradation of GLI1 by the proteasome R-HSA-5610780
RNA Polymerase II Transcription R-HSA-73857
Signaling by ROBO receptors R-HSA-376176
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Hedgehog R-HSA-5358351
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular responses to stress R-HSA-2262752
Hedgehog 'on' state R-HSA-5632684
G1/S DNA Damage Checkpoints R-HSA-69615
Hedgehog 'off' state R-HSA-5610787
S Phase R-HSA-69242
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Stabilization of p53 R-HSA-69541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PTEN Regulation R-HSA-6807070
MAPK6/MAPK4 signaling R-HSA-5687128
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
Metabolism of RNA R-HSA-8953854
Transport of small molecules R-HSA-382551
Metabolism of amino acids and derivatives R-HSA-71291
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Regulation of RUNX2 expression and activity R-HSA-8939902
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
Intracellular signaling by second messengers R-HSA-9006925
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'on' state R-HSA-5632684
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Interleukins R-HSA-449147
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by WNT R-HSA-195721
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Neddylation R-HSA-8951664
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
FCERI mediated NF-kB activation R-HSA-2871837
Transport of small molecules R-HSA-382551
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by Hedgehog R-HSA-5358351
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
Cellular response to chemical stress R-HSA-9711123
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
UCH proteinases R-HSA-5689603
Immune System R-HSA-168256
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Hedgehog 'off' state R-HSA-5610787
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Nervous system development R-HSA-9675108
Gene expression (Transcription) R-HSA-74160
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle R-HSA-1640170
HIV Infection R-HSA-162906
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ER-Phagosome pathway R-HSA-1236974
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Programmed Cell Death R-HSA-5357801
Synthesis of DNA R-HSA-69239
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism R-HSA-1430728
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stimuli R-HSA-8953897
M Phase R-HSA-68886
Axon guidance R-HSA-422475
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Developmental Biology R-HSA-1266738
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Ub-specific processing proteases R-HSA-5689880
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
S Phase R-HSA-69242
Signal Transduction R-HSA-162582
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Metabolism of proteins R-HSA-392499
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of beta-catenin by the destruction complex R-HSA-195253
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream TCR signaling R-HSA-202424
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
CLEC7A (Dectin-1) signaling R-HSA-5607764
Mitotic Metaphase and Anaphase R-HSA-2555396
ER-Phagosome pathway R-HSA-1236974
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Post-translational protein modification R-HSA-597592
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
RNA Polymerase II Transcription R-HSA-73857
G2/M Transition R-HSA-69275
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by Interleukins R-HSA-449147
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PIP3 activates AKT signaling R-HSA-1257604
KEAP1-NFE2L2 pathway R-HSA-9755511
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Generic Transcription Pathway R-HSA-212436
Switching of origins to a post-replicative state R-HSA-69052
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RAS by GAPs R-HSA-5658442
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
Degradation of GLI1 by the proteasome R-HSA-5610780
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular response to chemical stress R-HSA-9711123
RAF/MAP kinase cascade R-HSA-5673001
PCP/CE pathway R-HSA-4086400
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog 'off' state R-HSA-5610787
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Intracellular signaling by second messengers R-HSA-9006925
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Gene expression (Transcription) R-HSA-74160
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of RNA R-HSA-8953854
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication R-HSA-69306
Adaptive Immune System R-HSA-1280218
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle, Mitotic R-HSA-69278
Metabolism of polyamines R-HSA-351202
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 signaling R-HSA-9020702
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Signal Transduction R-HSA-162582
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disease R-HSA-1643685
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481

Expression Atlas ENSG00000154611
NCBI gene (formerly Entrezgene) 143471
GeneCards 22985
HGNC Symbol HGNC:22985
MIM gene 617841
UniProtKB Gene Name Q8TAA3
WikiGene 143471