Gene: NPY4R
Ensembl ID : ENSG00000204174
Description: neuropeptide Y receptor Y4
Gene Synonyms: PP1,PPYR1,Y4
1 APIs:
115 Possible Orthologues:

Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000204174
NCBI gene (formerly Entrezgene) 5540
GeneCards 9329
HGNC Symbol HGNC:9329
MIM gene 601790
UniProtKB Gene Name P50391
WikiGene 5540
Gene: MLNR
Ensembl ID : ENSG00000102539
Description: motilin receptor
Gene Synonyms: GPR38
3 APIs:
163 Possible Orthologues:

G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476

Expression Atlas ENSG00000102539
NCBI gene (formerly Entrezgene) 2862
GeneCards 4495
HGNC Symbol HGNC:4495
MIM gene 602885
UniProtKB Gene Name O43193
WikiGene 2862
Gene: F2R
Ensembl ID : ENSG00000181104
Description: coagulation factor II thrombin receptor
Gene Synonyms: CF2R,PAR-1,PAR1,TR
3 APIs:
330 Possible Orthologues:

GPCR downstream signalling R-HSA-388396
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Common Pathway of Fibrin Clot Formation R-HSA-140875
G alpha (q) signalling events R-HSA-416476
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Platelet activation, signaling and aggregation R-HSA-76002
Peptide ligand-binding receptors R-HSA-375276
Hemostasis R-HSA-109582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Peptide ligand-binding receptors R-HSA-375276
Common Pathway of Fibrin Clot Formation R-HSA-140875
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Platelet activation, signaling and aggregation R-HSA-76002
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Common Pathway of Fibrin Clot Formation R-HSA-140875
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Common Pathway of Fibrin Clot Formation R-HSA-140875
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Peptide ligand-binding receptors R-HSA-375276
Hemostasis R-HSA-109582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Common Pathway of Fibrin Clot Formation R-HSA-140875
G alpha (q) signalling events R-HSA-416476
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Common Pathway of Fibrin Clot Formation R-HSA-140875
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Platelet activation, signaling and aggregation R-HSA-76002
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
Common Pathway of Fibrin Clot Formation R-HSA-140875
GPCR downstream signalling R-HSA-388396
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
GPCR downstream signalling R-HSA-388396
Platelet activation, signaling and aggregation R-HSA-76002
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Common Pathway of Fibrin Clot Formation R-HSA-140875
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Common Pathway of Fibrin Clot Formation R-HSA-140875
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Hemostasis R-HSA-109582
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
GPCR downstream signalling R-HSA-388396
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Common Pathway of Fibrin Clot Formation R-HSA-140875
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790

Expression Atlas ENSG00000181104
LRG display in Ensembl gene LRG_641
NCBI gene (formerly Entrezgene) 2149
GeneCards 3537
HGNC Symbol HGNC:3537
MIM gene 187930
UniProtKB Gene Name P25116
WikiGene 2149
Gene: GABBR2
Ensembl ID : ENSG00000136928
Description: gamma-aminobutyric acid type B receptor subunit 2
Gene Synonyms: GABABR2,GPR51,GPRC3B,HG20
8 APIs:
208 Possible Orthologues:

Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Activation of G protein gated Potassium channels R-HSA-1296041
GABA receptor activation R-HSA-977443
Signal Transduction R-HSA-162582
Activation of GABAB receptors R-HSA-991365
Neuronal System R-HSA-112316
GABA B receptor activation R-HSA-977444
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
G protein gated Potassium channels R-HSA-1296059
Potassium Channels R-HSA-1296071
Signaling by GPCR R-HSA-372790
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
G alpha (i) signalling events R-HSA-418594
Inwardly rectifying K+ channels R-HSA-1296065
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
G alpha (i) signalling events R-HSA-418594
GPCR ligand binding R-HSA-500792
Transmission across Chemical Synapses R-HSA-112315
GABA B receptor activation R-HSA-977444
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Activation of GABAB receptors R-HSA-991365
Signal Transduction R-HSA-162582
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
GPCR downstream signalling R-HSA-388396
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
GABA receptor activation R-HSA-977443
Signaling by GPCR R-HSA-372790
Potassium Channels R-HSA-1296071
G protein gated Potassium channels R-HSA-1296059
Inwardly rectifying K+ channels R-HSA-1296065
Activation of G protein gated Potassium channels R-HSA-1296041
Signal Transduction R-HSA-162582
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
Transmission across Chemical Synapses R-HSA-112315
Activation of G protein gated Potassium channels R-HSA-1296041
Neuronal System R-HSA-112316
GABA receptor activation R-HSA-977443
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
GABA B receptor activation R-HSA-977444
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Inwardly rectifying K+ channels R-HSA-1296065
G protein gated Potassium channels R-HSA-1296059
Activation of GABAB receptors R-HSA-991365
Potassium Channels R-HSA-1296071
GPCR downstream signalling R-HSA-388396
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G alpha (i) signalling events R-HSA-418594
Activation of GABAB receptors R-HSA-991365
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR ligand binding R-HSA-500792
G protein gated Potassium channels R-HSA-1296059
GABA receptor activation R-HSA-977443
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Transmission across Chemical Synapses R-HSA-112315
G alpha (i) signalling events R-HSA-418594
Neuronal System R-HSA-112316
Potassium Channels R-HSA-1296071
Activation of G protein gated Potassium channels R-HSA-1296041
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
GABA B receptor activation R-HSA-977444
Inwardly rectifying K+ channels R-HSA-1296065
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
Signal Transduction R-HSA-162582
GABA B receptor activation R-HSA-977444
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
Potassium Channels R-HSA-1296071
Inwardly rectifying K+ channels R-HSA-1296065
GPCR downstream signalling R-HSA-388396
Transmission across Chemical Synapses R-HSA-112315
G protein gated Potassium channels R-HSA-1296059
GABA receptor activation R-HSA-977443
Neuronal System R-HSA-112316
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR ligand binding R-HSA-500792
Activation of GABAB receptors R-HSA-991365
Activation of G protein gated Potassium channels R-HSA-1296041
G protein gated Potassium channels R-HSA-1296059
G alpha (i) signalling events R-HSA-418594
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
Potassium Channels R-HSA-1296071
GPCR ligand binding R-HSA-500792
Transmission across Chemical Synapses R-HSA-112315
Activation of GABAB receptors R-HSA-991365
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
GABA B receptor activation R-HSA-977444
GABA receptor activation R-HSA-977443
Signaling by GPCR R-HSA-372790
Inwardly rectifying K+ channels R-HSA-1296065
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Activation of G protein gated Potassium channels R-HSA-1296041
Neuronal System R-HSA-112316
Inwardly rectifying K+ channels R-HSA-1296065
Activation of GABAB receptors R-HSA-991365
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
Neuronal System R-HSA-112316
GPCR ligand binding R-HSA-500792
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Activation of G protein gated Potassium channels R-HSA-1296041
Transmission across Chemical Synapses R-HSA-112315
Potassium Channels R-HSA-1296071
GABA receptor activation R-HSA-977443
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
G protein gated Potassium channels R-HSA-1296059
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
GABA B receptor activation R-HSA-977444
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
GABA receptor activation R-HSA-977443
Activation of GABAB receptors R-HSA-991365
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
G alpha (i) signalling events R-HSA-418594
Neuronal System R-HSA-112316
Activation of G protein gated Potassium channels R-HSA-1296041
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
Potassium Channels R-HSA-1296071
G protein gated Potassium channels R-HSA-1296059
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signal Transduction R-HSA-162582
Inwardly rectifying K+ channels R-HSA-1296065
GABA B receptor activation R-HSA-977444
Transmission across Chemical Synapses R-HSA-112315
GABA B receptor activation R-HSA-977444
Signal Transduction R-HSA-162582
Activation of G protein gated Potassium channels R-HSA-1296041
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Neuronal System R-HSA-112316
Signaling by GPCR R-HSA-372790
Potassium Channels R-HSA-1296071
GABA receptor activation R-HSA-977443
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
G protein gated Potassium channels R-HSA-1296059
GPCR ligand binding R-HSA-500792
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
Activation of GABAB receptors R-HSA-991365
Inwardly rectifying K+ channels R-HSA-1296065
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499
Signal Transduction R-HSA-162582
Inwardly rectifying K+ channels R-HSA-1296065
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
G protein gated Potassium channels R-HSA-1296059
Activation of G protein gated Potassium channels R-HSA-1296041
Signaling by GPCR R-HSA-372790
Activation of GABAB receptors R-HSA-991365
GPCR ligand binding R-HSA-500792
Potassium Channels R-HSA-1296071
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272
GPCR downstream signalling R-HSA-388396
GABA B receptor activation R-HSA-977444
G alpha (i) signalling events R-HSA-418594
GABA receptor activation R-HSA-977443

Expression Atlas ENSG00000136928
NCBI gene (formerly Entrezgene) 9568
GeneCards 4507
HGNC Symbol HGNC:4507
MIM gene 607340
MIM morbid 617904
UniProtKB Gene Name O75899
WikiGene 9568
Gene: EDNRB
Ensembl ID : ENSG00000136160
Description: endothelin receptor type B
Gene Synonyms: ETB,HSCR,HSCR2
4 APIs:
267 Possible Orthologues:

Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
Peptide ligand-binding receptors R-HSA-375276
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Peptide ligand-binding receptors R-HSA-375276
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Peptide ligand-binding receptors R-HSA-375276
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790

Expression Atlas ENSG00000136160
NCBI gene (formerly Entrezgene) 1910
GeneCards 3180
HGNC Symbol HGNC:3180
MIM gene 131244
MIM morbid 600501
UniProtKB Gene Name P24530
WikiGene 1910
Gene: P2RY1
Ensembl ID : ENSG00000169860
Description: purinergic receptor P2Y1
Gene Synonyms: P2Y1,SARCC
1 APIs:
191 Possible Orthologues:

GPCR ligand binding R-HSA-500792
Signal amplification R-HSA-392518
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Nucleotide-like (purinergic) receptors R-HSA-418038
Hemostasis R-HSA-109582
P2Y receptors R-HSA-417957
G alpha (q) signalling events R-HSA-416476
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
Nucleotide-like (purinergic) receptors R-HSA-418038
Platelet activation, signaling and aggregation R-HSA-76002
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Signal amplification R-HSA-392518
G alpha (q) signalling events R-HSA-416476
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
P2Y receptors R-HSA-417957
P2Y receptors R-HSA-417957
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Platelet activation, signaling and aggregation R-HSA-76002
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Signal amplification R-HSA-392518
Hemostasis R-HSA-109582
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
Nucleotide-like (purinergic) receptors R-HSA-418038
Signal Transduction R-HSA-162582
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR downstream signalling R-HSA-388396
Signal amplification R-HSA-392518
Platelet activation, signaling and aggregation R-HSA-76002
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
P2Y receptors R-HSA-417957
Hemostasis R-HSA-109582
G alpha (q) signalling events R-HSA-416476
Signaling by GPCR R-HSA-372790
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Hemostasis R-HSA-109582
P2Y receptors R-HSA-417957
G alpha (q) signalling events R-HSA-416476
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Signal amplification R-HSA-392518
Platelet activation, signaling and aggregation R-HSA-76002
GPCR ligand binding R-HSA-500792
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
P2Y receptors R-HSA-417957
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Signal amplification R-HSA-392518
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Platelet activation, signaling and aggregation R-HSA-76002
GPCR ligand binding R-HSA-500792
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
G alpha (q) signalling events R-HSA-416476
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Nucleotide-like (purinergic) receptors R-HSA-418038
Signaling by GPCR R-HSA-372790
P2Y receptors R-HSA-417957
Signal amplification R-HSA-392518
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Signal amplification R-HSA-392518
P2Y receptors R-HSA-417957
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR ligand binding R-HSA-500792
Hemostasis R-HSA-109582
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Signal Transduction R-HSA-162582
Signal amplification R-HSA-392518
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Nucleotide-like (purinergic) receptors R-HSA-418038
P2Y receptors R-HSA-417957
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
ADP signalling through P2Y purinoceptor 1 R-HSA-418592
Signal amplification R-HSA-392518
P2Y receptors R-HSA-417957
G alpha (q) signalling events R-HSA-416476
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
GPCR ligand binding R-HSA-500792
Nucleotide-like (purinergic) receptors R-HSA-418038
Signaling by GPCR R-HSA-372790

Expression Atlas ENSG00000169860
LRG display in Ensembl gene LRG_635
NCBI gene (formerly Entrezgene) 5028
GeneCards 8539
HGNC Symbol HGNC:8539
MIM gene 601167
UniProtKB Gene Name P47900
WikiGene 5028
Gene: TLR4
Ensembl ID : ENSG00000136869
Description: toll like receptor 4
Gene Synonyms: ARMD10,CD284,HTOLL,TLR-4
1 APIs:
127 Possible Orthologues:

Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Diseases associated with the TLR signaling cascade R-HSA-5602358
Innate Immune System R-HSA-168249
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Class I MHC mediated antigen processing & presentation R-HSA-983169
ER-Phagosome pathway R-HSA-1236974
IKK complex recruitment mediated by RIP1 R-HSA-937041
Apoptosis R-HSA-109581
Heme signaling R-HSA-9707616
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Antigen processing-Cross presentation R-HSA-1236975
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
TRIF-mediated programmed cell death R-HSA-2562578
Regulation of TLR by endogenous ligand R-HSA-5686938
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Diseases of Immune System R-HSA-5260271
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 deficiency (TLR2/4) R-HSA-5602498
MyD88 deficiency (TLR2/4) R-HSA-5602498
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
IRAK4 deficiency (TLR2/4) R-HSA-5603041
TRIF-mediated programmed cell death R-HSA-2562578
Class I MHC mediated antigen processing & presentation R-HSA-983169
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
Regulation of TLR by endogenous ligand R-HSA-5686938
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Programmed Cell Death R-HSA-5357801
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Diseases of Immune System R-HSA-5260271
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Apoptosis R-HSA-109581
IKK complex recruitment mediated by RIP1 R-HSA-937041
Antigen processing-Cross presentation R-HSA-1236975
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Diseases associated with the TLR signaling cascade R-HSA-5602358
Cellular responses to stimuli R-HSA-8953897
Heme signaling R-HSA-9707616
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Diseases associated with the TLR signaling cascade R-HSA-5602358
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Programmed Cell Death R-HSA-5357801
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
Toll-like Receptor Cascades R-HSA-168898
Antigen processing-Cross presentation R-HSA-1236975
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Heme signaling R-HSA-9707616
IKK complex recruitment mediated by RIP1 R-HSA-937041
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF-mediated programmed cell death R-HSA-2562578
MyD88 deficiency (TLR2/4) R-HSA-5602498
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Immune System R-HSA-168256
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Diseases of Immune System R-HSA-5260271
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of TLR by endogenous ligand R-HSA-5686938
Innate Immune System R-HSA-168249
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Adaptive Immune System R-HSA-1280218
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptosis R-HSA-109581
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Regulation of TLR by endogenous ligand R-HSA-5686938
Adaptive Immune System R-HSA-1280218
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Toll-like Receptor Cascades R-HSA-168898
Antigen processing-Cross presentation R-HSA-1236975
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Programmed Cell Death R-HSA-5357801
Cellular responses to stimuli R-HSA-8953897
MyD88-independent TLR4 cascade R-HSA-166166
TRIF-mediated programmed cell death R-HSA-2562578
Innate Immune System R-HSA-168249
Diseases associated with the TLR signaling cascade R-HSA-5602358
MyD88 deficiency (TLR2/4) R-HSA-5602498
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
IRAK4 deficiency (TLR2/4) R-HSA-5603041
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
MyD88 dependent cascade initiated on endosome R-HSA-975155
Heme signaling R-HSA-9707616
Disease R-HSA-1643685
Diseases of Immune System R-HSA-5260271
IKK complex recruitment mediated by RIP1 R-HSA-937041
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular responses to stress R-HSA-2262752
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Immune System R-HSA-168256
ER-Phagosome pathway R-HSA-1236974
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Disease R-HSA-1643685
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Diseases associated with the TLR signaling cascade R-HSA-5602358
IKK complex recruitment mediated by RIP1 R-HSA-937041
Cellular responses to stress R-HSA-2262752
MyD88-independent TLR4 cascade R-HSA-166166
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Antigen processing-Cross presentation R-HSA-1236975
Diseases of Immune System R-HSA-5260271
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRIF-mediated programmed cell death R-HSA-2562578
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Innate Immune System R-HSA-168249
Heme signaling R-HSA-9707616
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll-like Receptor Cascades R-HSA-168898
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
MyD88 deficiency (TLR2/4) R-HSA-5602498
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Regulation of TLR by endogenous ligand R-HSA-5686938
Programmed Cell Death R-HSA-5357801
IRAK4 deficiency (TLR2/4) R-HSA-5603041
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Innate Immune System R-HSA-168249
Antigen processing-Cross presentation R-HSA-1236975
Apoptosis R-HSA-109581
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases associated with the TLR signaling cascade R-HSA-5602358
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
TRIF-mediated programmed cell death R-HSA-2562578
Toll-like Receptor Cascades R-HSA-168898
Regulation of TLR by endogenous ligand R-HSA-5686938
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Heme signaling R-HSA-9707616
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 deficiency (TLR2/4) R-HSA-5602498
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Diseases of Immune System R-HSA-5260271
MyD88 dependent cascade initiated on endosome R-HSA-975155
IKK complex recruitment mediated by RIP1 R-HSA-937041
ER-Phagosome pathway R-HSA-1236974
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Programmed Cell Death R-HSA-5357801
MyD88 deficiency (TLR2/4) R-HSA-5602498
IKK complex recruitment mediated by RIP1 R-HSA-937041
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ER-Phagosome pathway R-HSA-1236974
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Heme signaling R-HSA-9707616
Innate Immune System R-HSA-168249
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Apoptosis R-HSA-109581
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Antigen processing-Cross presentation R-HSA-1236975
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Diseases of Immune System R-HSA-5260271
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Regulation of TLR by endogenous ligand R-HSA-5686938
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Diseases associated with the TLR signaling cascade R-HSA-5602358
TRIF-mediated programmed cell death R-HSA-2562578
MyD88 dependent cascade initiated on endosome R-HSA-975155
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
MyD88 dependent cascade initiated on endosome R-HSA-975155
IKK complex recruitment mediated by RIP1 R-HSA-937041
Apoptosis R-HSA-109581
IRAK4 deficiency (TLR2/4) R-HSA-5603041
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Diseases of Immune System R-HSA-5260271
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Regulation of TLR by endogenous ligand R-HSA-5686938
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Diseases associated with the TLR signaling cascade R-HSA-5602358
TRIF-mediated programmed cell death R-HSA-2562578
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing-Cross presentation R-HSA-1236975
Programmed Cell Death R-HSA-5357801
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
MyD88 deficiency (TLR2/4) R-HSA-5602498
Heme signaling R-HSA-9707616
Immune System R-HSA-168256
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
ER-Phagosome pathway R-HSA-1236974
Cellular responses to stress R-HSA-2262752
Toll-like Receptor Cascades R-HSA-168898
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Heme signaling R-HSA-9707616
Diseases associated with the TLR signaling cascade R-HSA-5602358
Immune System R-HSA-168256
Cellular responses to stimuli R-HSA-8953897
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
TRIF-mediated programmed cell death R-HSA-2562578
IRAK4 deficiency (TLR2/4) R-HSA-5603041
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
MyD88 deficiency (TLR2/4) R-HSA-5602498
Toll-like Receptor Cascades R-HSA-168898
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TLR by endogenous ligand R-HSA-5686938
Antigen processing-Cross presentation R-HSA-1236975
MyD88-independent TLR4 cascade R-HSA-166166
IKK complex recruitment mediated by RIP1 R-HSA-937041
Diseases of Immune System R-HSA-5260271
Innate Immune System R-HSA-168249
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Antigen processing-Cross presentation R-HSA-1236975
IKK complex recruitment mediated by RIP1 R-HSA-937041
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Diseases associated with the TLR signaling cascade R-HSA-5602358
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRIF-mediated programmed cell death R-HSA-2562578
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072
Regulation of TLR by endogenous ligand R-HSA-5686938
MyD88 deficiency (TLR2/4) R-HSA-5602498
IRAK4 deficiency (TLR2/4) R-HSA-5603041
ER-Phagosome pathway R-HSA-1236974
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Apoptosis R-HSA-109581
Cellular responses to stimuli R-HSA-8953897
Programmed Cell Death R-HSA-5357801
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon R-HSA-936964
Adaptive Immune System R-HSA-1280218
Class I MHC mediated antigen processing & presentation R-HSA-983169
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Diseases of Immune System R-HSA-5260271
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Heme signaling R-HSA-9707616
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163

Expression Atlas ENSG00000136869
LRG display in Ensembl gene LRG_320
NCBI gene (formerly Entrezgene) 7099
GeneCards 11850
HGNC Symbol HGNC:11850
MIM gene 603030
UniProtKB Gene Name O00206
WikiGene 7099
Gene: P2RY4
Ensembl ID : ENSG00000186912
Description: pyrimidinergic receptor P2Y4
Gene Synonyms: NRU,P2P,P2Y4,UNR
1 APIs:
168 Possible Orthologues:

G alpha (i) signalling events R-HSA-418594
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
P2Y receptors R-HSA-417957
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
GPCR downstream signalling R-HSA-388396
P2Y receptors R-HSA-417957
GPCR ligand binding R-HSA-500792
Nucleotide-like (purinergic) receptors R-HSA-418038
Signaling by GPCR R-HSA-372790
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signal Transduction R-HSA-162582
P2Y receptors R-HSA-417957
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
G alpha (i) signalling events R-HSA-418594
Signaling by GPCR R-HSA-372790
Nucleotide-like (purinergic) receptors R-HSA-418038
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR downstream signalling R-HSA-388396
GPCR ligand binding R-HSA-500792
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
P2Y receptors R-HSA-417957
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
Nucleotide-like (purinergic) receptors R-HSA-418038
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
P2Y receptors R-HSA-417957
G alpha (i) signalling events R-HSA-418594
P2Y receptors R-HSA-417957
GPCR downstream signalling R-HSA-388396
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Nucleotide-like (purinergic) receptors R-HSA-418038
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
GPCR ligand binding R-HSA-500792
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
Signaling by GPCR R-HSA-372790
Nucleotide-like (purinergic) receptors R-HSA-418038
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
P2Y receptors R-HSA-417957
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
GPCR ligand binding R-HSA-500792
GPCR downstream signalling R-HSA-388396
G alpha (i) signalling events R-HSA-418594
Class A/1 (Rhodopsin-like receptors) R-HSA-373076
P2Y receptors R-HSA-417957
Nucleotide-like (purinergic) receptors R-HSA-418038

Expression Atlas ENSG00000186912
NCBI gene (formerly Entrezgene) 5030
GeneCards 8542
HGNC Symbol HGNC:8542
MIM gene 300038
UniProtKB Gene Name P51582
WikiGene 5030