Gene: PDPK1
Ensembl ID : ENSG00000140992
Description: 3-phosphoinositide dependent protein kinase 1
Gene Synonyms: PDK1
2 APIs:
234 Possible Orthologues:

Signaling by Insulin receptor R-HSA-74752
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of TP53 Degradation R-HSA-6804757
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
C-type lectin receptors (CLRs) R-HSA-5621481
Transmission across Chemical Synapses R-HSA-112315
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of TP53 Activity R-HSA-5633007
Signal Transduction R-HSA-162582
RHO GTPases activate PKNs R-HSA-5625740
ESR-mediated signaling R-HSA-8939211
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Infectious disease R-HSA-5663205
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Generic Transcription Pathway R-HSA-212436
CD28 dependent PI3K/Akt signaling R-HSA-389357
Platelet Aggregation (Plug Formation) R-HSA-76009
SARS-CoV-1-host interactions R-HSA-9692914
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional Regulation by TP53 R-HSA-3700989
Innate Immune System R-HSA-168249
VEGFR2 mediated cell proliferation R-HSA-5218921
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Post NMDA receptor activation events R-HSA-438064
IRS-mediated signalling R-HSA-112399
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
CD28 co-stimulation R-HSA-389356
Integrin signaling R-HSA-354192
RHO GTPase Effectors R-HSA-195258
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
IGF1R signaling cascade R-HSA-2428924
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
SARS-CoV Infections R-HSA-9679506
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2-host interactions R-HSA-9705683
Platelet activation, signaling and aggregation R-HSA-76002
GPVI-mediated activation cascade R-HSA-114604
Costimulation by the CD28 family R-HSA-388841
SARS-CoV-1 Infection R-HSA-9678108
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
Gene expression (Transcription) R-HSA-74160
Signaling by GPCR R-HSA-372790
PI3K Cascade R-HSA-109704
RSK activation R-HSA-444257
Immune System R-HSA-168256
Signaling by Rho GTPases R-HSA-194315
Adaptive Immune System R-HSA-1280218
VEGFR2 mediated vascular permeability R-HSA-5218920
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Activation of AKT2 R-HSA-165158
IRS-related events triggered by IGF1R R-HSA-2428928
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
PI3K/AKT Signaling in Cancer R-HSA-2219528
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G-protein beta:gamma signalling R-HSA-397795
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neuronal System R-HSA-112316
SARS-CoV-2-host interactions R-HSA-9705683
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Generic Transcription Pathway R-HSA-212436
Neuronal System R-HSA-112316
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional Regulation by TP53 R-HSA-3700989
IRS-related events triggered by IGF1R R-HSA-2428928
RNA Polymerase II Transcription R-HSA-73857
VEGFR2 mediated vascular permeability R-HSA-5218920
SARS-CoV-1 Infection R-HSA-9678108
Signaling by Insulin receptor R-HSA-74752
VEGFR2 mediated cell proliferation R-HSA-5218921
Transmission across Chemical Synapses R-HSA-112315
Innate Immune System R-HSA-168249
Costimulation by the CD28 family R-HSA-388841
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
CD28 co-stimulation R-HSA-389356
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity R-HSA-5633007
IRS-mediated signalling R-HSA-112399
Gene expression (Transcription) R-HSA-74160
ESR-mediated signaling R-HSA-8939211
Regulation of TP53 Degradation R-HSA-6804757
PI3K Cascade R-HSA-109704
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TCR signaling R-HSA-202403
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
RSK activation R-HSA-444257
IGF1R signaling cascade R-HSA-2428924
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Post NMDA receptor activation events R-HSA-438064
Intracellular signaling by second messengers R-HSA-9006925
Signaling by VEGF R-HSA-194138
Hemostasis R-HSA-109582
FCERI mediated NF-kB activation R-HSA-2871837
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CD28 dependent PI3K/Akt signaling R-HSA-389357
CLEC7A (Dectin-1) signaling R-HSA-5607764
RHO GTPase Effectors R-HSA-195258
SARS-CoV-2 Infection R-HSA-9694516
Integrin signaling R-HSA-354192
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet Aggregation (Plug Formation) R-HSA-76009
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Disease R-HSA-1643685
Platelet activation, signaling and aggregation R-HSA-76002
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV-1-host interactions R-HSA-9692914
G-protein beta:gamma signalling R-HSA-397795
PI3K/AKT Signaling in Cancer R-HSA-2219528
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
PIP3 activates AKT signaling R-HSA-1257604
Activation of AKT2 R-HSA-165158
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Signaling by Nuclear Receptors R-HSA-9006931
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
VEGFA-VEGFR2 Pathway R-HSA-4420097
Insulin receptor signalling cascade R-HSA-74751
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
IRS-mediated signalling R-HSA-112399
VEGFA-VEGFR2 Pathway R-HSA-4420097
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
FCERI mediated NF-kB activation R-HSA-2871837
Integrin signaling R-HSA-354192
C-type lectin receptors (CLRs) R-HSA-5621481
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
RNA Polymerase II Transcription R-HSA-73857
Signaling by VEGF R-HSA-194138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Costimulation by the CD28 family R-HSA-388841
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
SARS-CoV-1-host interactions R-HSA-9692914
RSK activation R-HSA-444257
SARS-CoV-1 Infection R-HSA-9678108
RHO GTPase Effectors R-HSA-195258
CD28 co-stimulation R-HSA-389356
Signaling by Nuclear Receptors R-HSA-9006931
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Activation of AKT2 R-HSA-165158
PI3K Cascade R-HSA-109704
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Regulation of TP53 Degradation R-HSA-6804757
Neuronal System R-HSA-112316
Gene expression (Transcription) R-HSA-74160
Hemostasis R-HSA-109582
PIP3 activates AKT signaling R-HSA-1257604
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Rho GTPases R-HSA-194315
Signaling by GPCR R-HSA-372790
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Adaptive Immune System R-HSA-1280218
VEGFR2 mediated vascular permeability R-HSA-5218920
Regulation of TP53 Activity R-HSA-5633007
GPVI-mediated activation cascade R-HSA-114604
Extra-nuclear estrogen signaling R-HSA-9009391
Generic Transcription Pathway R-HSA-212436
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet activation, signaling and aggregation R-HSA-76002
SARS-CoV Infections R-HSA-9679506
Platelet Aggregation (Plug Formation) R-HSA-76009
Post NMDA receptor activation events R-HSA-438064
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
PI3K/AKT Signaling in Cancer R-HSA-2219528
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GPCR downstream signalling R-HSA-388396
Intracellular signaling by second messengers R-HSA-9006925
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transmission across Chemical Synapses R-HSA-112315
Disease R-HSA-1643685
G beta:gamma signalling through PI3Kgamma R-HSA-392451
ESR-mediated signaling R-HSA-8939211
IGF1R signaling cascade R-HSA-2428924
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G-protein beta:gamma signalling R-HSA-397795
RHO GTPase Effectors R-HSA-195258
Platelet Aggregation (Plug Formation) R-HSA-76009
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-1 Infection R-HSA-9678108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G-protein beta:gamma signalling R-HSA-397795
GPVI-mediated activation cascade R-HSA-114604
SARS-CoV-1-host interactions R-HSA-9692914
FCERI mediated NF-kB activation R-HSA-2871837
Gene expression (Transcription) R-HSA-74160
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by GPCR R-HSA-372790
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
VEGFR2 mediated cell proliferation R-HSA-5218921
Regulation of TP53 Expression and Degradation R-HSA-6806003
CD28 dependent PI3K/Akt signaling R-HSA-389357
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
C-type lectin receptors (CLRs) R-HSA-5621481
Insulin receptor signalling cascade R-HSA-74751
Activation of AKT2 R-HSA-165158
SARS-CoV-2 Infection R-HSA-9694516
CD28 co-stimulation R-HSA-389356
RNA Polymerase II Transcription R-HSA-73857
Costimulation by the CD28 family R-HSA-388841
Extra-nuclear estrogen signaling R-HSA-9009391
IRS-related events triggered by IGF1R R-HSA-2428928
Transcriptional Regulation by TP53 R-HSA-3700989
Infectious disease R-HSA-5663205
Post NMDA receptor activation events R-HSA-438064
Neuronal System R-HSA-112316
SARS-CoV-2-host interactions R-HSA-9705683
IRS-mediated signalling R-HSA-112399
RSK activation R-HSA-444257
Immune System R-HSA-168256
ESR-mediated signaling R-HSA-8939211
Transmission across Chemical Synapses R-HSA-112315
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Downstream TCR signaling R-HSA-202424
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHO GTPases activate PKNs R-HSA-5625740
TCR signaling R-HSA-202403
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV Infections R-HSA-9679506
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
GPCR downstream signalling R-HSA-388396
Hemostasis R-HSA-109582
Signaling by Rho GTPases R-HSA-194315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
PI3K Cascade R-HSA-109704
VEGFR2 mediated vascular permeability R-HSA-5218920
Platelet activation, signaling and aggregation R-HSA-76002
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
Integrin signaling R-HSA-354192
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
GPVI-mediated activation cascade R-HSA-114604
Regulation of TP53 Expression and Degradation R-HSA-6806003
C-type lectin receptors (CLRs) R-HSA-5621481
ESR-mediated signaling R-HSA-8939211
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Post NMDA receptor activation events R-HSA-438064
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
RSK activation R-HSA-444257
SARS-CoV-1 Infection R-HSA-9678108
Generic Transcription Pathway R-HSA-212436
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by GPCR R-HSA-372790
SARS-CoV-2-host interactions R-HSA-9705683
SARS-CoV-2 Infection R-HSA-9694516
PI3K Cascade R-HSA-109704
Activation of AKT2 R-HSA-165158
Signaling by Nuclear Receptors R-HSA-9006931
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Activity R-HSA-5633007
FCERI mediated NF-kB activation R-HSA-2871837
RNA Polymerase II Transcription R-HSA-73857
SARS-CoV-1-host interactions R-HSA-9692914
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
VEGFR2 mediated cell proliferation R-HSA-5218921
Extra-nuclear estrogen signaling R-HSA-9009391
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-mediated signalling R-HSA-112399
Integrin signaling R-HSA-354192
Regulation of TP53 Degradation R-HSA-6804757
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
RHO GTPases activate PKNs R-HSA-5625740
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet activation, signaling and aggregation R-HSA-76002
Adaptive Immune System R-HSA-1280218
Transcriptional Regulation by TP53 R-HSA-3700989
SARS-CoV Infections R-HSA-9679506
IRS-related events triggered by IGF1R R-HSA-2428928
Infectious disease R-HSA-5663205
CD28 dependent PI3K/Akt signaling R-HSA-389357
CD28 co-stimulation R-HSA-389356
Gene expression (Transcription) R-HSA-74160
Transmission across Chemical Synapses R-HSA-112315
G-protein beta:gamma signalling R-HSA-397795
VEGFA-VEGFR2 Pathway R-HSA-4420097
Neuronal System R-HSA-112316
Signaling by Insulin receptor R-HSA-74752
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Insulin receptor signalling cascade R-HSA-74751
VEGFR2 mediated vascular permeability R-HSA-5218920
Immune System R-HSA-168256
Costimulation by the CD28 family R-HSA-388841
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase Effectors R-HSA-195258
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream TCR signaling R-HSA-202424
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
IGF1R signaling cascade R-HSA-2428924
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
CLEC7A (Dectin-1) signaling R-HSA-5607764
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
CLEC7A (Dectin-1) signaling R-HSA-5607764
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
CD28 dependent PI3K/Akt signaling R-HSA-389357
RNA Polymerase II Transcription R-HSA-73857
G-protein beta:gamma signalling R-HSA-397795
Integrin signaling R-HSA-354192
Insulin receptor signalling cascade R-HSA-74751
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-1 Infection R-HSA-9678108
Downstream TCR signaling R-HSA-202424
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
IRS-mediated signalling R-HSA-112399
TCR signaling R-HSA-202403
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Immune System R-HSA-168256
Activation of AKT2 R-HSA-165158
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Regulation of TP53 Activity R-HSA-5633007
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
SARS-CoV-1-host interactions R-HSA-9692914
FCERI mediated NF-kB activation R-HSA-2871837
VEGFR2 mediated cell proliferation R-HSA-5218921
Post NMDA receptor activation events R-HSA-438064
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of TP53 Expression and Degradation R-HSA-6806003
C-type lectin receptors (CLRs) R-HSA-5621481
RHO GTPase Effectors R-HSA-195258
CD28 co-stimulation R-HSA-389356
Hemostasis R-HSA-109582
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Nuclear Receptors R-HSA-9006931
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extra-nuclear estrogen signaling R-HSA-9009391
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Transmission across Chemical Synapses R-HSA-112315
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Neuronal System R-HSA-112316
ESR-mediated signaling R-HSA-8939211
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
PI3K Cascade R-HSA-109704
RHO GTPases activate PKNs R-HSA-5625740
SARS-CoV Infections R-HSA-9679506
Costimulation by the CD28 family R-HSA-388841
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by VEGF R-HSA-194138
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by GPCR R-HSA-372790
Adaptive Immune System R-HSA-1280218
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Rho GTPases R-HSA-194315
RSK activation R-HSA-444257
GPCR downstream signalling R-HSA-388396
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-related events triggered by IGF1R R-HSA-2428928
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by Rho GTPases R-HSA-194315
IGF1R signaling cascade R-HSA-2428924
CD28 co-stimulation R-HSA-389356
FCERI mediated NF-kB activation R-HSA-2871837
Transmission across Chemical Synapses R-HSA-112315
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Insulin receptor signalling cascade R-HSA-74751
PI3K/AKT Signaling in Cancer R-HSA-2219528
Neuronal System R-HSA-112316
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV-2 Infection R-HSA-9694516
Signaling by VEGF R-HSA-194138
Regulation of TP53 Activity R-HSA-5633007
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV Infections R-HSA-9679506
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by GPCR R-HSA-372790
Activation of AKT2 R-HSA-165158
Adaptive Immune System R-HSA-1280218
RHO GTPases activate PKNs R-HSA-5625740
Signal Transduction R-HSA-162582
Integrin signaling R-HSA-354192
Disease R-HSA-1643685
Downstream TCR signaling R-HSA-202424
Signaling by Nuclear Receptors R-HSA-9006931
Extra-nuclear estrogen signaling R-HSA-9009391
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
IRS-related events triggered by IGF1R R-HSA-2428928
ESR-mediated signaling R-HSA-8939211
RHO GTPase Effectors R-HSA-195258
VEGFR2 mediated cell proliferation R-HSA-5218921
Post NMDA receptor activation events R-HSA-438064
Costimulation by the CD28 family R-HSA-388841
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Activation of NMDA receptors and postsynaptic events R-HSA-442755
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
RSK activation R-HSA-444257
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Transcriptional Regulation by TP53 R-HSA-3700989
SARS-CoV-1-host interactions R-HSA-9692914
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-1 Infection R-HSA-9678108
Immune System R-HSA-168256
SARS-CoV-2-host interactions R-HSA-9705683
Platelet Aggregation (Plug Formation) R-HSA-76009
IRS-mediated signalling R-HSA-112399
Infectious disease R-HSA-5663205
Hemostasis R-HSA-109582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Gene expression (Transcription) R-HSA-74160
G-protein beta:gamma signalling R-HSA-397795
TCR signaling R-HSA-202403
Regulation of TP53 Degradation R-HSA-6804757
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
C-type lectin receptors (CLRs) R-HSA-5621481
PI3K Cascade R-HSA-109704
VEGFR2 mediated vascular permeability R-HSA-5218920
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002
GPCR downstream signalling R-HSA-388396
Costimulation by the CD28 family R-HSA-388841
Immune System R-HSA-168256
Insulin receptor signalling cascade R-HSA-74751
VEGFR2 mediated vascular permeability R-HSA-5218920
GPVI-mediated activation cascade R-HSA-114604
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002
PIP3 activates AKT signaling R-HSA-1257604
Neuronal System R-HSA-112316
Generic Transcription Pathway R-HSA-212436
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by VEGF R-HSA-194138
Downstream TCR signaling R-HSA-202424
VEGFA-VEGFR2 Pathway R-HSA-4420097
SARS-CoV-2-host interactions R-HSA-9705683
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by GPCR R-HSA-372790
CD28 co-stimulation R-HSA-389356
Signal Transduction R-HSA-162582
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of TP53 Degradation R-HSA-6804757
PI3K Cascade R-HSA-109704
RSK activation R-HSA-444257
Regulation of TP53 Activity R-HSA-5633007
Adaptive Immune System R-HSA-1280218
G-protein beta:gamma signalling R-HSA-397795
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet Aggregation (Plug Formation) R-HSA-76009
Transcriptional Regulation by TP53 R-HSA-3700989
RHO GTPases activate PKNs R-HSA-5625740
Extra-nuclear estrogen signaling R-HSA-9009391
SARS-CoV Infections R-HSA-9679506
IRS-related events triggered by IGF1R R-HSA-2428928
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K/AKT Signaling in Cancer R-HSA-2219528
Intracellular signaling by second messengers R-HSA-9006925
IGF1R signaling cascade R-HSA-2428924
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Integrin signaling R-HSA-354192
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Gene expression (Transcription) R-HSA-74160
IRS-mediated signalling R-HSA-112399
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
RNA Polymerase II Transcription R-HSA-73857
RHO GTPase Effectors R-HSA-195258
Signaling by Nuclear Receptors R-HSA-9006931
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of TP53 Expression and Degradation R-HSA-6806003
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Transmission across Chemical Synapses R-HSA-112315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2 Infection R-HSA-9694516
Activation of AKT2 R-HSA-165158
Post NMDA receptor activation events R-HSA-438064
Disease R-HSA-1643685
SARS-CoV-1-host interactions R-HSA-9692914
CD28 dependent PI3K/Akt signaling R-HSA-389357
C-type lectin receptors (CLRs) R-HSA-5621481
ESR-mediated signaling R-HSA-8939211
CLEC7A (Dectin-1) signaling R-HSA-5607764
PI3K Cascade R-HSA-109704
Neuronal System R-HSA-112316
ESR-mediated signaling R-HSA-8939211
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Activation of AKT2 R-HSA-165158
Signal Transduction R-HSA-162582
Regulation of TP53 Degradation R-HSA-6804757
Signaling by Nuclear Receptors R-HSA-9006931
GPCR downstream signalling R-HSA-388396
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G-protein beta:gamma signalling R-HSA-397795
Gene expression (Transcription) R-HSA-74160
SARS-CoV-2 Infection R-HSA-9694516
PIP3 activates AKT signaling R-HSA-1257604
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
SARS-CoV-2-host interactions R-HSA-9705683
Platelet activation, signaling and aggregation R-HSA-76002
Insulin receptor signalling cascade R-HSA-74751
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity R-HSA-5633007
IGF1R signaling cascade R-HSA-2428924
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
Signaling by VEGF R-HSA-194138
Extra-nuclear estrogen signaling R-HSA-9009391
RSK activation R-HSA-444257
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
Signaling by Rho GTPases R-HSA-194315
Costimulation by the CD28 family R-HSA-388841
Post NMDA receptor activation events R-HSA-438064
Disease R-HSA-1643685
VEGFR2 mediated cell proliferation R-HSA-5218921
Adaptive Immune System R-HSA-1280218
Integrin signaling R-HSA-354192
CD28 dependent PI3K/Akt signaling R-HSA-389357
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
RHO GTPases activate PKNs R-HSA-5625740
VEGFA-VEGFR2 Pathway R-HSA-4420097
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Innate Immune System R-HSA-168249
Transmission across Chemical Synapses R-HSA-112315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Hemostasis R-HSA-109582
SARS-CoV-1 Infection R-HSA-9678108
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
GPVI-mediated activation cascade R-HSA-114604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Downstream TCR signaling R-HSA-202424
IRS-mediated signalling R-HSA-112399
Infectious disease R-HSA-5663205
Regulation of TP53 Expression and Degradation R-HSA-6806003
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional Regulation by TP53 R-HSA-3700989
Platelet Aggregation (Plug Formation) R-HSA-76009
CD28 co-stimulation R-HSA-389356
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SARS-CoV Infections R-HSA-9679506
PI3K/AKT Signaling in Cancer R-HSA-2219528
C-type lectin receptors (CLRs) R-HSA-5621481
IRS-related events triggered by IGF1R R-HSA-2428928
RNA Polymerase II Transcription R-HSA-73857
VEGFR2 mediated vascular permeability R-HSA-5218920
RNA Polymerase II Transcription R-HSA-73857
CLEC7A (Dectin-1) signaling R-HSA-5607764
SARS-CoV-2 Infection R-HSA-9694516
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Platelet Aggregation (Plug Formation) R-HSA-76009
Signaling by Insulin receptor R-HSA-74752
Activation of AKT2 R-HSA-165158
PIP3 activates AKT signaling R-HSA-1257604
Transmission across Chemical Synapses R-HSA-112315
RHO GTPases activate PKNs R-HSA-5625740
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional Regulation by TP53 R-HSA-3700989
Disease R-HSA-1643685
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
VEGFR2 mediated cell proliferation R-HSA-5218921
RHO GTPase Effectors R-HSA-195258
Costimulation by the CD28 family R-HSA-388841
G beta:gamma signalling through PI3Kgamma R-HSA-392451
Integrin signaling R-HSA-354192
GPCR downstream signalling R-HSA-388396
Regulation of TP53 Activity R-HSA-5633007
SARS-CoV Infections R-HSA-9679506
Regulation of TP53 Degradation R-HSA-6804757
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by GPCR R-HSA-372790
Hemostasis R-HSA-109582
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Immune System R-HSA-168256
SARS-CoV-1 Infection R-HSA-9678108
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of TP53 Expression and Degradation R-HSA-6806003
G-protein beta:gamma signalling R-HSA-397795
Innate Immune System R-HSA-168249
RSK activation R-HSA-444257
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
TCR signaling R-HSA-202403
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Rho GTPases R-HSA-194315
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
SARS-CoV-1-host interactions R-HSA-9692914
Generic Transcription Pathway R-HSA-212436
Post NMDA receptor activation events R-HSA-438064
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
VEGFR2 mediated vascular permeability R-HSA-5218920
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
IGF1R signaling cascade R-HSA-2428924
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by VEGF R-HSA-194138
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CD28 dependent PI3K/Akt signaling R-HSA-389357
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Neuronal System R-HSA-112316
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream TCR signaling R-HSA-202424
CD28 co-stimulation R-HSA-389356
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
IRS-mediated signalling R-HSA-112399
C-type lectin receptors (CLRs) R-HSA-5621481
Platelet activation, signaling and aggregation R-HSA-76002
PI3K Cascade R-HSA-109704
FCERI mediated NF-kB activation R-HSA-2871837
GPVI-mediated activation cascade R-HSA-114604
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Degradation R-HSA-6804757
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NMDA receptors and postsynaptic events R-HSA-442755
SARS-CoV-1-host interactions R-HSA-9692914
Activation of AKT2 R-HSA-165158
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CD28 co-stimulation R-HSA-389356
G beta:gamma signalling through PI3Kgamma R-HSA-392451
PI3K/AKT Signaling in Cancer R-HSA-2219528
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SARS-CoV-2 Infection R-HSA-9694516
Hemostasis R-HSA-109582
CD28 dependent PI3K/Akt signaling R-HSA-389357
Gene expression (Transcription) R-HSA-74160
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
GPCR downstream signalling R-HSA-388396
Insulin receptor signalling cascade R-HSA-74751
PIP3 activates AKT signaling R-HSA-1257604
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
SARS-CoV Infections R-HSA-9679506
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS-related events triggered by IGF1R R-HSA-2428928
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G-protein beta:gamma signalling R-HSA-397795
SARS-CoV-1 Infection R-HSA-9678108
Generic Transcription Pathway R-HSA-212436
RSK activation R-HSA-444257
CLEC7A (Dectin-1) signaling R-HSA-5607764
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
VEGFR2 mediated cell proliferation R-HSA-5218921
Regulation of TP53 Expression and Degradation R-HSA-6806003
Signaling by GPCR R-HSA-372790
Post NMDA receptor activation events R-HSA-438064
RHO GTPase Effectors R-HSA-195258
Platelet Aggregation (Plug Formation) R-HSA-76009
RHO GTPases activate PKNs R-HSA-5625740
Disease R-HSA-1643685
SARS-CoV-2-host interactions R-HSA-9705683
Transmission across Chemical Synapses R-HSA-112315
VEGFR2 mediated vascular permeability R-HSA-5218920
IGF1R signaling cascade R-HSA-2428924
Transcriptional Regulation by TP53 R-HSA-3700989
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
TCR signaling R-HSA-202403
Neuronal System R-HSA-112316
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Integrin signaling R-HSA-354192
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream TCR signaling R-HSA-202424
Signaling by VEGF R-HSA-194138
Signaling by Rho GTPases R-HSA-194315
Intracellular signaling by second messengers R-HSA-9006925
VEGFA-VEGFR2 Pathway R-HSA-4420097
ESR-mediated signaling R-HSA-8939211
Costimulation by the CD28 family R-HSA-388841
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Insulin receptor R-HSA-74752
Platelet activation, signaling and aggregation R-HSA-76002

Expression Atlas ENSG00000140992
NCBI gene (formerly Entrezgene) 5170
GeneCards 8816
HGNC Symbol HGNC:8816
MIM gene 605213
UniProtKB Gene Name O15530
WikiGene 5170
Gene: FGFR2
Ensembl ID : ENSG00000066468
Description: fibroblast growth factor receptor 2
Gene Synonyms: BEK,CD332,CEK3,CFD1,ECT1,JWS,K-SAM,KGFR,TK14,TK25
27 APIs:
218 Possible Orthologues:

Activated point mutants of FGFR2 R-HSA-2033519
PI3K Cascade R-HSA-109704
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR2c ligand binding and activation R-HSA-190375
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by FGFR2 R-HSA-5654738
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
FGFR2 mutant receptor activation R-HSA-1839126
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Disease R-HSA-1643685
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Signaling by FGFR2 in disease R-HSA-5655253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
Insulin receptor signalling cascade R-HSA-74751
FGFR2 ligand binding and activation R-HSA-190241
FGFR2b ligand binding and activation R-HSA-190377
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Downstream signaling of activated FGFR2 R-HSA-5654696
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR2 signaling R-HSA-5654727
Activated point mutants of FGFR2 R-HSA-2033519
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
FGFR2 mutant receptor activation R-HSA-1839126
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR2 IIIa TM R-HSA-8851708
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2 alternative splicing R-HSA-6803529
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Activated point mutants of FGFR2 R-HSA-2033519
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2 alternative splicing R-HSA-6803529
FGFR2c ligand binding and activation R-HSA-190375
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by FGFR2 IIIa TM R-HSA-8851708
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 mutant receptor activation R-HSA-1839126
PI3K Cascade R-HSA-109704
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
FGFR2b ligand binding and activation R-HSA-190377
Disease R-HSA-1643685
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR2 in disease R-HSA-5655253
RAF/MAP kinase cascade R-HSA-5673001
FRS-mediated FGFR2 signaling R-HSA-5654700
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR2 ligand binding and activation R-HSA-190241
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2c ligand binding and activation R-HSA-190375
Signaling by FGFR R-HSA-190236
Downstream signaling of activated FGFR2 R-HSA-5654696
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR2 R-HSA-5654738
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
SHC-mediated cascade:FGFR2 R-HSA-5654699
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR2 R-HSA-5654695
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR2 IIIa TM R-HSA-8851708
FGFR2 ligand binding and activation R-HSA-190241
PI3K Cascade R-HSA-109704
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 in disease R-HSA-5655253
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2b ligand binding and activation R-HSA-190377
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by FGFR in disease R-HSA-1226099
FGFR2c ligand binding and activation R-HSA-190375
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
SHC-mediated cascade:FGFR2 R-HSA-5654699
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
Disease R-HSA-1643685
IRS-related events triggered by IGF1R R-HSA-2428928
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR2 alternative splicing R-HSA-6803529
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 in disease R-HSA-5655253
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 amplification mutants R-HSA-2023837
IRS-related events triggered by IGF1R R-HSA-2428928
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF/MAP kinase cascade R-HSA-5673001
IRS-mediated signalling R-HSA-112399
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Disease R-HSA-1643685
Downstream signaling of activated FGFR2 R-HSA-5654696
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2b ligand binding and activation R-HSA-190377
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 amplification mutants R-HSA-2023837
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 mutant receptor activation R-HSA-1839126
Signal Transduction R-HSA-162582
FRS-mediated FGFR2 signaling R-HSA-5654700
IRS-mediated signalling R-HSA-112399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
FGFR2c ligand binding and activation R-HSA-190375
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 ligand binding and activation R-HSA-190241
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR2 alternative splicing R-HSA-6803529
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
Insulin receptor signalling cascade R-HSA-74751
FGFR2b ligand binding and activation R-HSA-190377
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 amplification mutants R-HSA-2023837
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by FGFR2 fusions R-HSA-8853333
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2c ligand binding and activation R-HSA-190375
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 ligand binding and activation R-HSA-190241
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2b ligand binding and activation R-HSA-190377
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR2 in disease R-HSA-5655253
IRS-mediated signalling R-HSA-112399
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
FGFR2 alternative splicing R-HSA-6803529
Signal Transduction R-HSA-162582
FGFR2 mutant receptor activation R-HSA-1839126
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 in disease R-HSA-5655253
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR in disease R-HSA-1226099
Disease R-HSA-1643685
Negative regulation of FGFR2 signaling R-HSA-5654727
PIP3 activates AKT signaling R-HSA-1257604
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
FGFR2b ligand binding and activation R-HSA-190377
IRS-mediated signalling R-HSA-112399
FGFR2c ligand binding and activation R-HSA-190375
IGF1R signaling cascade R-HSA-2428924
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR2 R-HSA-5654695
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 IIIa TM R-HSA-8851708
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2b ligand binding and activation R-HSA-190377
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 fusions R-HSA-8853333
Negative regulation of FGFR2 signaling R-HSA-5654727
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR R-HSA-190236
Activated point mutants of FGFR2 R-HSA-2033519
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI-3K cascade:FGFR2 R-HSA-5654695
MAPK1/MAPK3 signaling R-HSA-5684996
FRS-mediated FGFR2 signaling R-HSA-5654700
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2 ligand binding and activation R-HSA-190241
FGFR2 alternative splicing R-HSA-6803529
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-mediated signalling R-HSA-112399

Expression Atlas ENSG00000066468
LRG display in Ensembl gene LRG_994
NCBI gene (formerly Entrezgene) 2263
GeneCards 3689
HGNC Symbol HGNC:3689
MIM gene 176943
MIM morbid 614592
UniProtKB Gene Name S4R3B2
WikiGene 2263
Gene: FDFT1
Ensembl ID : ENSG00000079459
Description: farnesyl-diphosphate farnesyltransferase 1
Gene Synonyms: SQS
1 APIs:
218 Possible Orthologues:

Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
PPARA activates gene expression R-HSA-1989781
Metabolism R-HSA-1430728
Cholesterol biosynthesis R-HSA-191273
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism of steroids R-HSA-8957322
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
PPARA activates gene expression R-HSA-1989781
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
Cholesterol biosynthesis R-HSA-191273
Metabolism R-HSA-1430728
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cholesterol biosynthesis R-HSA-191273
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Metabolism of lipids R-HSA-556833
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
Cholesterol biosynthesis R-HSA-191273
Metabolism R-HSA-1430728
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cholesterol biosynthesis R-HSA-191273
PPARA activates gene expression R-HSA-1989781
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
PPARA activates gene expression R-HSA-1989781
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cholesterol biosynthesis R-HSA-191273
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of steroids R-HSA-8957322
Cholesterol biosynthesis R-HSA-191273
PPARA activates gene expression R-HSA-1989781
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
PPARA activates gene expression R-HSA-1989781
Cholesterol biosynthesis R-HSA-191273
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Cholesterol biosynthesis R-HSA-191273
PPARA activates gene expression R-HSA-1989781
Metabolism of lipids R-HSA-556833
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Activation of gene expression by SREBF (SREBP) R-HSA-2426168

Expression Atlas ENSG00000079459
NCBI gene (formerly Entrezgene) 2222
GeneCards 3629
HGNC Symbol HGNC:3629
MIM gene 184420
MIM morbid 618156
UniProtKB Gene Name Q6IAX1
WikiGene 2222
Gene: PIM1
Ensembl ID : ENSG00000137193
Description: Pim-1 proto-oncogene, serine/threonine kinase
Gene Synonyms: PIM
3 APIs:
248 Possible Orthologues:

Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FLT3 fusion proteins R-HSA-9703465
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Signaling by FLT3 fusion proteins R-HSA-9703465
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
FLT3 signaling in disease R-HSA-9682385
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Disease R-HSA-1643685
FLT3 signaling in disease R-HSA-9682385
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Immune System R-HSA-168256
Signaling by FLT3 fusion proteins R-HSA-9703465
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
FLT3 signaling in disease R-HSA-9682385
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by FLT3 fusion proteins R-HSA-9703465
FLT3 signaling in disease R-HSA-9682385
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Immune System R-HSA-168256
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FLT3 fusion proteins R-HSA-9703465
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
FLT3 signaling in disease R-HSA-9682385
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by FLT3 fusion proteins R-HSA-9703465
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
Disease R-HSA-1643685
Signaling by FLT3 fusion proteins R-HSA-9703465
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147

Expression Atlas ENSG00000137193
NCBI gene (formerly Entrezgene) 5292
GeneCards 8986
HGNC Symbol HGNC:8986
MIM gene 164960
UniProtKB Gene Name P11309
WikiGene 5292
Gene: HDAC3
Ensembl ID : ENSG00000171720
Description: histone deacetylase 3
Gene Synonyms: HD3,KDAC3,RPD3,RPD3-2
10 APIs:
156 Possible Orthologues:

Signaling by NOTCH R-HSA-157118
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by Nuclear Receptors R-HSA-9006931
Activation of HOX genes during differentiation R-HSA-5619507
HCMV Early Events R-HSA-9609690
Chromatin modifying enzymes R-HSA-3247509
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 in Cancer R-HSA-2644603
Cellular response to chemical stress R-HSA-9711123
p75 NTR receptor-mediated signalling R-HSA-193704
Circadian Clock R-HSA-400253
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Metabolism R-HSA-1430728
Gene expression (Transcription) R-HSA-74160
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Cytoprotection by HMOX1 R-HSA-9707564
Chaperonin-mediated protein folding R-HSA-390466
Death Receptor Signaling R-HSA-73887
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Infectious disease R-HSA-5663205
Notch-HLH transcription pathway R-HSA-350054
Mitochondrial biogenesis R-HSA-1592230
Generic Transcription Pathway R-HSA-212436
HCMV Infection R-HSA-9609646
Regulation of MECP2 expression and activity R-HSA-9022692
Developmental Biology R-HSA-1266738
Organelle biogenesis and maintenance R-HSA-1852241
Pervasive developmental disorders R-HSA-9005895
Transcriptional regulation by RUNX2 R-HSA-8878166
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
HDACs deacetylate histones R-HSA-3214815
Cellular responses to stress R-HSA-2262752
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Chromatin organization R-HSA-4839726
Heme signaling R-HSA-9707616
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Metabolism of lipids R-HSA-556833
Protein folding R-HSA-391251
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
PPARA activates gene expression R-HSA-1989781
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
Disorders of Nervous System Development R-HSA-9697154
Signal Transduction R-HSA-162582
PTEN Regulation R-HSA-6807070
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Signaling by NOTCH R-HSA-157118
Disorders of Developmental Biology R-HSA-9675151
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stimuli R-HSA-8953897
Signaling by ALK R-HSA-201556
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
RUNX2 regulates bone development R-HSA-8941326
Signaling by NOTCH1 R-HSA-1980143
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Regulation of PTEN gene transcription R-HSA-8943724
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Pervasive developmental disorders R-HSA-9005895
Chromatin organization R-HSA-4839726
Signaling by NOTCH1 in Cancer R-HSA-2644603
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of HOX genes during differentiation R-HSA-5619507
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Chaperonin-mediated protein folding R-HSA-390466
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Disorders of Nervous System Development R-HSA-9697154
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Regulation of MECP2 expression and activity R-HSA-9022692
RUNX2 regulates bone development R-HSA-8941326
Signaling by NOTCH R-HSA-157118
Circadian Clock R-HSA-400253
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitochondrial biogenesis R-HSA-1592230
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Cellular response to chemical stress R-HSA-9711123
Infectious disease R-HSA-5663205
Intracellular signaling by second messengers R-HSA-9006925
Heme signaling R-HSA-9707616
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Protein folding R-HSA-391251
Disorders of Developmental Biology R-HSA-9675151
HCMV Early Events R-HSA-9609690
Cellular responses to stimuli R-HSA-8953897
Death Receptor Signaling R-HSA-73887
Disease R-HSA-1643685
Notch-HLH transcription pathway R-HSA-350054
Regulation of PTEN gene transcription R-HSA-8943724
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Developmental Biology R-HSA-1266738
p75 NTR receptor-mediated signalling R-HSA-193704
HDACs deacetylate histones R-HSA-3214815
HCMV Infection R-HSA-9609646
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Cellular responses to stress R-HSA-2262752
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by NOTCH1 R-HSA-1980143
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Generic Transcription Pathway R-HSA-212436
Chromatin modifying enzymes R-HSA-3247509
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Signaling by Nuclear Receptors R-HSA-9006931
Organelle biogenesis and maintenance R-HSA-1852241
Cytoprotection by HMOX1 R-HSA-9707564
PTEN Regulation R-HSA-6807070
PPARA activates gene expression R-HSA-1989781
Metabolism of proteins R-HSA-392499
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Signaling by ALK R-HSA-201556
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
RNA Polymerase II Transcription R-HSA-73857
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Notch-HLH transcription pathway R-HSA-350054
Gene expression (Transcription) R-HSA-74160
Pervasive developmental disorders R-HSA-9005895
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Death Receptor Signaling R-HSA-73887
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
RUNX2 regulates bone development R-HSA-8941326
Regulation of PTEN gene transcription R-HSA-8943724
Intracellular signaling by second messengers R-HSA-9006925
Chaperonin-mediated protein folding R-HSA-390466
Developmental Biology R-HSA-1266738
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Disorders of Nervous System Development R-HSA-9697154
Heme signaling R-HSA-9707616
Signaling by NOTCH R-HSA-157118
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Metabolism of lipids R-HSA-556833
Cellular responses to stress R-HSA-2262752
HDACs deacetylate histones R-HSA-3214815
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Metabolism R-HSA-1430728
Cellular responses to stimuli R-HSA-8953897
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by ALK R-HSA-201556
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Circadian Clock R-HSA-400253
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Regulation of MECP2 expression and activity R-HSA-9022692
Signaling by Nuclear Receptors R-HSA-9006931
Chromatin organization R-HSA-4839726
Signaling by NOTCH1 R-HSA-1980143
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Chromatin modifying enzymes R-HSA-3247509
PTEN Regulation R-HSA-6807070
HCMV Early Events R-HSA-9609690
Cellular response to chemical stress R-HSA-9711123
Mitochondrial biogenesis R-HSA-1592230
HCMV Infection R-HSA-9609646
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Activation of HOX genes during differentiation R-HSA-5619507
Transcriptional regulation by RUNX2 R-HSA-8878166
RNA Polymerase II Transcription R-HSA-73857
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Infectious disease R-HSA-5663205
Protein folding R-HSA-391251
Signaling by NOTCH1 in Cancer R-HSA-2644603
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Disorders of Developmental Biology R-HSA-9675151
Cytoprotection by HMOX1 R-HSA-9707564
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Transcriptional Regulation by MECP2 R-HSA-8986944
Organelle biogenesis and maintenance R-HSA-1852241
PPARA activates gene expression R-HSA-1989781
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Signal Transduction R-HSA-162582
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Regulation of MECP2 expression and activity R-HSA-9022692
Metabolism of lipids R-HSA-556833
Signaling by ALK R-HSA-201556
p75 NTR receptor-mediated signalling R-HSA-193704
Chromatin organization R-HSA-4839726
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Developmental Biology R-HSA-1266738
PPARA activates gene expression R-HSA-1989781
Activation of HOX genes during differentiation R-HSA-5619507
HCMV Infection R-HSA-9609646
Signaling by NOTCH R-HSA-157118
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Heme signaling R-HSA-9707616
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Transcriptional Regulation by MECP2 R-HSA-8986944
Chaperonin-mediated protein folding R-HSA-390466
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
PIP3 activates AKT signaling R-HSA-1257604
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Protein folding R-HSA-391251
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates bone development R-HSA-8941326
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Cellular response to chemical stress R-HSA-9711123
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
RNA Polymerase II Transcription R-HSA-73857
Chromatin modifying enzymes R-HSA-3247509
Organelle biogenesis and maintenance R-HSA-1852241
Gene expression (Transcription) R-HSA-74160
RUNX2 regulates osteoblast differentiation R-HSA-8940973
PTEN Regulation R-HSA-6807070
Disorders of Developmental Biology R-HSA-9675151
Signaling by NOTCH1 R-HSA-1980143
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Transcriptional regulation by RUNX2 R-HSA-8878166
Cytoprotection by HMOX1 R-HSA-9707564
Mitochondrial biogenesis R-HSA-1592230
Circadian Clock R-HSA-400253
Metabolism R-HSA-1430728
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Generic Transcription Pathway R-HSA-212436
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Disorders of Nervous System Development R-HSA-9697154
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Signaling by Nuclear Receptors R-HSA-9006931
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
HCMV Early Events R-HSA-9609690
Metabolism of proteins R-HSA-392499
HDACs deacetylate histones R-HSA-3214815
Regulation of PTEN gene transcription R-HSA-8943724
Notch-HLH transcription pathway R-HSA-350054
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Pervasive developmental disorders R-HSA-9005895
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Cellular responses to stress R-HSA-2262752
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Organelle biogenesis and maintenance R-HSA-1852241
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Disease R-HSA-1643685
HCMV Early Events R-HSA-9609690
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Cellular response to chemical stress R-HSA-9711123
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
HCMV Infection R-HSA-9609646
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Cellular responses to stimuli R-HSA-8953897
Signaling by ALK R-HSA-201556
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
Mitochondrial biogenesis R-HSA-1592230
Heme signaling R-HSA-9707616
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Nuclear Receptors R-HSA-9006931
Metabolism of proteins R-HSA-392499
PPARA activates gene expression R-HSA-1989781
Chromatin modifying enzymes R-HSA-3247509
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Activation of HOX genes during differentiation R-HSA-5619507
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Gene expression (Transcription) R-HSA-74160
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
p75 NTR receptor-mediated signalling R-HSA-193704
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
HDACs deacetylate histones R-HSA-3214815
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Disorders of Nervous System Development R-HSA-9697154
Infectious disease R-HSA-5663205
Notch-HLH transcription pathway R-HSA-350054
Chromatin organization R-HSA-4839726
Disorders of Developmental Biology R-HSA-9675151
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by NOTCH1 in Cancer R-HSA-2644603
PIP3 activates AKT signaling R-HSA-1257604
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Regulation of MECP2 expression and activity R-HSA-9022692
Metabolism R-HSA-1430728
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Pervasive developmental disorders R-HSA-9005895
Signaling by NOTCH1 R-HSA-1980143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of lipids R-HSA-556833
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Chaperonin-mediated protein folding R-HSA-390466
PTEN Regulation R-HSA-6807070
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Cytoprotection by HMOX1 R-HSA-9707564
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Regulation of PTEN gene transcription R-HSA-8943724
Circadian Clock R-HSA-400253
Protein folding R-HSA-391251
Intracellular signaling by second messengers R-HSA-9006925
RUNX2 regulates bone development R-HSA-8941326
Developmental Biology R-HSA-1266738
Signaling by ALK R-HSA-201556
Regulation of PTEN gene transcription R-HSA-8943724
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Cytoprotection by HMOX1 R-HSA-9707564
Organelle biogenesis and maintenance R-HSA-1852241
Chromatin organization R-HSA-4839726
p75 NTR receptor-mediated signalling R-HSA-193704
PPARA activates gene expression R-HSA-1989781
Mitochondrial biogenesis R-HSA-1592230
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 R-HSA-1980143
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Chromatin modifying enzymes R-HSA-3247509
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional Regulation by MECP2 R-HSA-8986944
Developmental Biology R-HSA-1266738
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Regulation of MECP2 expression and activity R-HSA-9022692
Protein folding R-HSA-391251
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NOTCH1 in Cancer R-HSA-2644603
Metabolism of proteins R-HSA-392499
Notch-HLH transcription pathway R-HSA-350054
Cellular responses to stress R-HSA-2262752
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Heme signaling R-HSA-9707616
Infectious disease R-HSA-5663205
Metabolism of lipids R-HSA-556833
HCMV Infection R-HSA-9609646
RUNX2 regulates bone development R-HSA-8941326
Pervasive developmental disorders R-HSA-9005895
Generic Transcription Pathway R-HSA-212436
Circadian Clock R-HSA-400253
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Disorders of Nervous System Development R-HSA-9697154
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Signaling by Nuclear Receptors R-HSA-9006931
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Disorders of Developmental Biology R-HSA-9675151
Cellular response to chemical stress R-HSA-9711123
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Chaperonin-mediated protein folding R-HSA-390466
RNA Polymerase II Transcription R-HSA-73857
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Intracellular signaling by second messengers R-HSA-9006925
HCMV Early Events R-HSA-9609690
Activation of HOX genes during differentiation R-HSA-5619507
HDACs deacetylate histones R-HSA-3214815
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
PTEN Regulation R-HSA-6807070
Cellular responses to stimuli R-HSA-8953897
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Signal Transduction R-HSA-162582
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ALK R-HSA-201556
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Transcriptional regulation by RUNX2 R-HSA-8878166
Pervasive developmental disorders R-HSA-9005895
PTEN Regulation R-HSA-6807070
Cellular responses to stimuli R-HSA-8953897
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Regulation of lipid metabolism by PPARalpha R-HSA-400206
p75 NTR receptor-mediated signalling R-HSA-193704
Mitochondrial biogenesis R-HSA-1592230
Cellular responses to stress R-HSA-2262752
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
HDACs deacetylate histones R-HSA-3214815
Gene expression (Transcription) R-HSA-74160
Heme signaling R-HSA-9707616
Circadian Clock R-HSA-400253
Protein folding R-HSA-391251
Notch-HLH transcription pathway R-HSA-350054
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Cellular response to chemical stress R-HSA-9711123
Signaling by NOTCH1 R-HSA-1980143
Chaperonin-mediated protein folding R-HSA-390466
Organelle biogenesis and maintenance R-HSA-1852241
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Regulation of MECP2 expression and activity R-HSA-9022692
Disorders of Nervous System Development R-HSA-9697154
Regulation of PTEN gene transcription R-HSA-8943724
Activation of HOX genes during differentiation R-HSA-5619507
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
PPARA activates gene expression R-HSA-1989781
Metabolism of lipids R-HSA-556833
Chromatin organization R-HSA-4839726
Death Receptor Signaling R-HSA-73887
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Disease R-HSA-1643685
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
RUNX2 regulates bone development R-HSA-8941326
Generic Transcription Pathway R-HSA-212436
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Nuclear Receptors R-HSA-9006931
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Infectious disease R-HSA-5663205
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by NOTCH1 in Cancer R-HSA-2644603
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Chromatin modifying enzymes R-HSA-3247509
HCMV Early Events R-HSA-9609690
HCMV Infection R-HSA-9609646
Metabolism R-HSA-1430728
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Cytoprotection by HMOX1 R-HSA-9707564
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disorders of Developmental Biology R-HSA-9675151
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
RUNX2 regulates bone development R-HSA-8941326
PPARA activates gene expression R-HSA-1989781
Signaling by ALK R-HSA-201556
Organelle biogenesis and maintenance R-HSA-1852241
Circadian Clock R-HSA-400253
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Cytoprotection by HMOX1 R-HSA-9707564
HDACs deacetylate histones R-HSA-3214815
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Mitochondrial biogenesis R-HSA-1592230
HCMV Early Events R-HSA-9609690
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Cellular responses to stimuli R-HSA-8953897
Signaling by NOTCH R-HSA-157118
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
HCMV Infection R-HSA-9609646
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Chromatin modifying enzymes R-HSA-3247509
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Cellular response to chemical stress R-HSA-9711123
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Chromatin organization R-HSA-4839726
Intracellular signaling by second messengers R-HSA-9006925
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Protein folding R-HSA-391251
Signaling by Nuclear Receptors R-HSA-9006931
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
Disorders of Nervous System Development R-HSA-9697154
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Metabolism of lipids R-HSA-556833
Signal Transduction R-HSA-162582
Heme signaling R-HSA-9707616
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Pervasive developmental disorders R-HSA-9005895
Signaling by NOTCH1 R-HSA-1980143
Regulation of MECP2 expression and activity R-HSA-9022692
PTEN Regulation R-HSA-6807070
Regulation of lipid metabolism by PPARalpha R-HSA-400206
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Signaling by NOTCH1 in Cancer R-HSA-2644603
p75 NTR receptor-mediated signalling R-HSA-193704
Chaperonin-mediated protein folding R-HSA-390466
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disorders of Developmental Biology R-HSA-9675151
Cellular responses to stress R-HSA-2262752
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Transcriptional Regulation by MECP2 R-HSA-8986944
Regulation of PTEN gene transcription R-HSA-8943724
Notch-HLH transcription pathway R-HSA-350054
Activation of HOX genes during differentiation R-HSA-5619507
Transcriptional regulation by RUNX2 R-HSA-8878166
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Metabolism of lipids R-HSA-556833
Chaperonin-mediated protein folding R-HSA-390466
Cellular responses to stress R-HSA-2262752
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RUNX2 regulates osteoblast differentiation R-HSA-8940973
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
HCMV Infection R-HSA-9609646
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Death Receptor Signaling R-HSA-73887
p75 NTR receptor-mediated signalling R-HSA-193704
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Pervasive developmental disorders R-HSA-9005895
RUNX2 regulates bone development R-HSA-8941326
Notch-HLH transcription pathway R-HSA-350054
Cellular responses to stimuli R-HSA-8953897
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Infectious disease R-HSA-5663205
Organelle biogenesis and maintenance R-HSA-1852241
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
HDACs deacetylate histones R-HSA-3214815
Generic Transcription Pathway R-HSA-212436
Chromatin organization R-HSA-4839726
Signal Transduction R-HSA-162582
PPARA activates gene expression R-HSA-1989781
Disorders of Nervous System Development R-HSA-9697154
HCMV Early Events R-HSA-9609690
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Protein folding R-HSA-391251
Cellular response to chemical stress R-HSA-9711123
Metabolism R-HSA-1430728
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
Transcriptional Regulation by MECP2 R-HSA-8986944
Intracellular signaling by second messengers R-HSA-9006925
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Circadian Clock R-HSA-400253
PTEN Regulation R-HSA-6807070
Mitochondrial biogenesis R-HSA-1592230
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201
Signaling by NOTCH1 R-HSA-1980143
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ALK R-HSA-201556
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Chromatin modifying enzymes R-HSA-3247509
Heme signaling R-HSA-9707616
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Regulation of MECP2 expression and activity R-HSA-9022692
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Activation of HOX genes during differentiation R-HSA-5619507
RNA Polymerase II Transcription R-HSA-73857
Disorders of Developmental Biology R-HSA-9675151
Signaling by NOTCH R-HSA-157118
Cytoprotection by HMOX1 R-HSA-9707564
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH1 in Cancer R-HSA-2644603
Disease R-HSA-1643685
Death Receptor Signaling R-HSA-73887
Cytoprotection by HMOX1 R-HSA-9707564
PTEN Regulation R-HSA-6807070
Signaling by Nuclear Receptors R-HSA-9006931
Chromatin organization R-HSA-4839726
NR1H2 and NR1H3-mediated signaling R-HSA-9024446
Regulation of lipid metabolism by PPARalpha R-HSA-400206
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Circadian Clock R-HSA-400253
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537
Disorders of Nervous System Development R-HSA-9697154
Metabolism R-HSA-1430728
Notch-HLH transcription pathway R-HSA-350054
Cellular responses to stimuli R-HSA-8953897
Regulation of MECP2 expression and activity R-HSA-9022692
Pervasive developmental disorders R-HSA-9005895
Signaling by NOTCH R-HSA-157118
HDACs deacetylate histones R-HSA-3214815
Organelle biogenesis and maintenance R-HSA-1852241
HCMV Infection R-HSA-9609646
Heme signaling R-HSA-9707616
Gene expression (Transcription) R-HSA-74160
Signaling by ALK R-HSA-201556
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Loss of function of MECP2 in Rett syndrome R-HSA-9005891
Metabolism of lipids R-HSA-556833
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Signal Transduction R-HSA-162582
Disorders of Developmental Biology R-HSA-9675151
Chromatin modifying enzymes R-HSA-3247509
RUNX2 regulates osteoblast differentiation R-HSA-8940973
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Protein folding R-HSA-391251
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Chaperonin-mediated protein folding R-HSA-390466
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
NR1D1 (REV-ERBA) represses gene expression R-HSA-1368071
Infectious disease R-HSA-5663205
RUNX2 regulates bone development R-HSA-8941326
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p75 NTR receptor-mediated signalling R-HSA-193704
Disease R-HSA-1643685
Signaling by NOTCH1 R-HSA-1980143
Mitochondrial biogenesis R-HSA-1592230
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
HCMV Early Events R-HSA-9609690
Transcriptional regulation by RUNX2 R-HSA-8878166
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by NOTCH1 in Cancer R-HSA-2644603
Metabolism of proteins R-HSA-392499
PPARA activates gene expression R-HSA-1989781
Cellular responses to stress R-HSA-2262752
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Intracellular signaling by second messengers R-HSA-9006925
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569
Activation of HOX genes during differentiation R-HSA-5619507
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201

Expression Atlas ENSG00000171720
NCBI gene (formerly Entrezgene) 8841
GeneCards 4854
HGNC Symbol HGNC:4854
MIM gene 605166
UniProtKB Gene Name O15379
WikiGene 8841
Gene: EZH2
Ensembl ID : ENSG00000106462
Description: enhancer of zeste 2 polycomb repressive complex 2 subunit
Gene Synonyms: ENX-1,EZH1,KMT6,KMT6A
2 APIs:
235 Possible Orthologues:

Epigenetic regulation of gene expression R-HSA-212165
Activation of HOX genes during differentiation R-HSA-5619507
Oxidative Stress Induced Senescence R-HSA-2559580
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Regulation of PTEN gene transcription R-HSA-8943724
Defective pyroptosis R-HSA-9710421
Disease R-HSA-1643685
Chromatin organization R-HSA-4839726
Transcriptional Regulation by E2F6 R-HSA-8953750
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
PTEN Regulation R-HSA-6807070
HCMV Early Events R-HSA-9609690
Cellular responses to stress R-HSA-2262752
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Signal Transduction R-HSA-162582
PKMTs methylate histone lysines R-HSA-3214841
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
HCMV Infection R-HSA-9609646
Cellular responses to stimuli R-HSA-8953897
PRC2 methylates histones and DNA R-HSA-212300
Generic Transcription Pathway R-HSA-212436
Chromatin modifying enzymes R-HSA-3247509
Diseases of programmed cell death R-HSA-9645723
Cellular Senescence R-HSA-2559583
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
Diseases of programmed cell death R-HSA-9645723
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
HCMV Infection R-HSA-9609646
Chromatin modifying enzymes R-HSA-3247509
Disease R-HSA-1643685
Transcriptional Regulation by E2F6 R-HSA-8953750
Chromatin organization R-HSA-4839726
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Activation of HOX genes during differentiation R-HSA-5619507
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of PTEN gene transcription R-HSA-8943724
Infectious disease R-HSA-5663205
Cellular Senescence R-HSA-2559583
Cellular responses to stimuli R-HSA-8953897
HCMV Early Events R-HSA-9609690
Defective pyroptosis R-HSA-9710421
PRC2 methylates histones and DNA R-HSA-212300
Oxidative Stress Induced Senescence R-HSA-2559580
PKMTs methylate histone lysines R-HSA-3214841
Epigenetic regulation of gene expression R-HSA-212165
HCMV Infection R-HSA-9609646
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Chromatin organization R-HSA-4839726
Cellular responses to stress R-HSA-2262752
HCMV Early Events R-HSA-9609690
PTEN Regulation R-HSA-6807070
Regulation of PTEN gene transcription R-HSA-8943724
Chromatin modifying enzymes R-HSA-3247509
Gene expression (Transcription) R-HSA-74160
Defective pyroptosis R-HSA-9710421
Cellular Senescence R-HSA-2559583
Diseases of programmed cell death R-HSA-9645723
PRC2 methylates histones and DNA R-HSA-212300
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
PKMTs methylate histone lysines R-HSA-3214841
Cellular responses to stimuli R-HSA-8953897
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Epigenetic regulation of gene expression R-HSA-212165
Oxidative Stress Induced Senescence R-HSA-2559580
PIP3 activates AKT signaling R-HSA-1257604
Activation of HOX genes during differentiation R-HSA-5619507
Transcriptional Regulation by E2F6 R-HSA-8953750
Disease R-HSA-1643685
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stress R-HSA-2262752
Diseases of programmed cell death R-HSA-9645723
HCMV Infection R-HSA-9609646
Cellular responses to stimuli R-HSA-8953897
Chromatin modifying enzymes R-HSA-3247509
Transcriptional Regulation by E2F6 R-HSA-8953750
Chromatin organization R-HSA-4839726
Regulation of PTEN gene transcription R-HSA-8943724
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Gene expression (Transcription) R-HSA-74160
HCMV Early Events R-HSA-9609690
Disease R-HSA-1643685
Oxidative Stress Induced Senescence R-HSA-2559580
Activation of HOX genes during differentiation R-HSA-5619507
PRC2 methylates histones and DNA R-HSA-212300
Infectious disease R-HSA-5663205
PTEN Regulation R-HSA-6807070
Intracellular signaling by second messengers R-HSA-9006925
Cellular Senescence R-HSA-2559583
Generic Transcription Pathway R-HSA-212436
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
PKMTs methylate histone lysines R-HSA-3214841
Epigenetic regulation of gene expression R-HSA-212165
Defective pyroptosis R-HSA-9710421
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
HCMV Infection R-HSA-9609646
Infectious disease R-HSA-5663205
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Activation of HOX genes during differentiation R-HSA-5619507
Oxidative Stress Induced Senescence R-HSA-2559580
HCMV Early Events R-HSA-9609690
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Signal Transduction R-HSA-162582
Chromatin organization R-HSA-4839726
Diseases of programmed cell death R-HSA-9645723
PKMTs methylate histone lysines R-HSA-3214841
Epigenetic regulation of gene expression R-HSA-212165
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by E2F6 R-HSA-8953750
Cellular Senescence R-HSA-2559583
Regulation of PTEN gene transcription R-HSA-8943724
Intracellular signaling by second messengers R-HSA-9006925
PRC2 methylates histones and DNA R-HSA-212300
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Defective pyroptosis R-HSA-9710421
Chromatin modifying enzymes R-HSA-3247509
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Activation of HOX genes during differentiation R-HSA-5619507
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Oxidative Stress Induced Senescence R-HSA-2559580
Infectious disease R-HSA-5663205
Signal Transduction R-HSA-162582
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Intracellular signaling by second messengers R-HSA-9006925
HCMV Infection R-HSA-9609646
Regulation of PTEN gene transcription R-HSA-8943724
Chromatin modifying enzymes R-HSA-3247509
Diseases of programmed cell death R-HSA-9645723
Gene expression (Transcription) R-HSA-74160
Chromatin organization R-HSA-4839726
HCMV Early Events R-HSA-9609690
Transcriptional Regulation by E2F6 R-HSA-8953750
PTEN Regulation R-HSA-6807070
Cellular Senescence R-HSA-2559583
Epigenetic regulation of gene expression R-HSA-212165
Disease R-HSA-1643685
PKMTs methylate histone lysines R-HSA-3214841
PRC2 methylates histones and DNA R-HSA-212300
Defective pyroptosis R-HSA-9710421
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of PTEN gene transcription R-HSA-8943724
Diseases of programmed cell death R-HSA-9645723
Epigenetic regulation of gene expression R-HSA-212165
PKMTs methylate histone lysines R-HSA-3214841
Chromatin modifying enzymes R-HSA-3247509
Chromatin organization R-HSA-4839726
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Transcriptional Regulation by E2F6 R-HSA-8953750
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Defective pyroptosis R-HSA-9710421
HCMV Infection R-HSA-9609646
Disease R-HSA-1643685
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
PRC2 methylates histones and DNA R-HSA-212300
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
HCMV Early Events R-HSA-9609690
Activation of HOX genes during differentiation R-HSA-5619507
Cellular responses to stimuli R-HSA-8953897
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
HCMV Infection R-HSA-9609646
Cellular Senescence R-HSA-2559583
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
Activation of HOX genes during differentiation R-HSA-5619507
Regulation of PTEN gene transcription R-HSA-8943724
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Transcriptional Regulation by E2F6 R-HSA-8953750
Oxidative Stress Induced Senescence R-HSA-2559580
Defective pyroptosis R-HSA-9710421
Infectious disease R-HSA-5663205
Cellular responses to stimuli R-HSA-8953897
Chromatin organization R-HSA-4839726
Gene expression (Transcription) R-HSA-74160
PTEN Regulation R-HSA-6807070
Chromatin modifying enzymes R-HSA-3247509
Epigenetic regulation of gene expression R-HSA-212165
Diseases of programmed cell death R-HSA-9645723
HCMV Early Events R-HSA-9609690
PRC2 methylates histones and DNA R-HSA-212300
RNA Polymerase II Transcription R-HSA-73857
PKMTs methylate histone lysines R-HSA-3214841
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Activation of HOX genes during differentiation R-HSA-5619507
HCMV Early Events R-HSA-9609690
PRC2 methylates histones and DNA R-HSA-212300
Cellular Senescence R-HSA-2559583
Regulation of PTEN gene transcription R-HSA-8943724
Oxidative Stress Induced Senescence R-HSA-2559580
PTEN Regulation R-HSA-6807070
Transcriptional Regulation by E2F6 R-HSA-8953750
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
Epigenetic regulation of gene expression R-HSA-212165
Intracellular signaling by second messengers R-HSA-9006925
PKMTs methylate histone lysines R-HSA-3214841
Gene expression (Transcription) R-HSA-74160
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472
Generic Transcription Pathway R-HSA-212436
Chromatin modifying enzymes R-HSA-3247509
HCMV Infection R-HSA-9609646
Chromatin organization R-HSA-4839726
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
Diseases of programmed cell death R-HSA-9645723
Signal Transduction R-HSA-162582
Defective pyroptosis R-HSA-9710421

Expression Atlas ENSG00000106462
LRG display in Ensembl gene LRG_531
NCBI gene (formerly Entrezgene) 2146
GeneCards 3527
HGNC Symbol HGNC:3527
MIM gene 601573
MIM morbid 277590
UniProtKB Gene Name S4S3R8
WikiGene 2146
Gene: HDAC2
Ensembl ID : ENSG00000196591
Description: histone deacetylase 2
Gene Synonyms: KDAC2,RPD3,YAF1
10 APIs:
203 Possible Orthologues:

Signaling by NOTCH1 in Cancer R-HSA-2644603
RNA Polymerase I Transcription R-HSA-73864
HDACs deacetylate histones R-HSA-3214815
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
SUMOylation R-HSA-2990846
Notch-HLH transcription pathway R-HSA-350054
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 in Cancer R-HSA-2644603
RNA Polymerase I Promoter Clearance R-HSA-73854
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Infectious disease R-HSA-5663205
Regulation of MECP2 expression and activity R-HSA-9022692
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
SUMOylation of chromatin organization proteins R-HSA-4551638
Hemostasis R-HSA-109582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Generic Transcription Pathway R-HSA-212436
RNA Polymerase I Transcription Initiation R-HSA-73762
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Chromatin organization R-HSA-4839726
Signaling by NOTCH R-HSA-157118
Disease R-HSA-1643685
p75 NTR receptor-mediated signalling R-HSA-193704
Transcriptional Regulation by TP53 R-HSA-3700989
Epigenetic regulation of gene expression R-HSA-212165
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Signaling by ALK R-HSA-201556
RNA Polymerase II Transcription R-HSA-73857
Positive epigenetic regulation of rRNA expression R-HSA-5250913
SARS-CoV Infections R-HSA-9679506
RNA Polymerase I Transcription R-HSA-73864
PTEN Regulation R-HSA-6807070
Factors involved in megakaryocyte development and platelet production R-HSA-983231
NoRC negatively regulates rRNA expression R-HSA-427413
Regulation of PTEN gene transcription R-HSA-8943724
Transcriptional Regulation by MECP2 R-HSA-8986944
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Intracellular signaling by second messengers R-HSA-9006925
Chromatin modifying enzymes R-HSA-3247509
Signal Transduction R-HSA-162582
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
FOXO-mediated transcription R-HSA-9614085
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Developmental Biology R-HSA-1266738
Post-translational protein modification R-HSA-597592
Potential therapeutics for SARS R-HSA-9679191
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Death Receptor Signaling R-HSA-73887
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 R-HSA-1980143
RNA Polymerase I Promoter Clearance R-HSA-73854
Developmental Biology R-HSA-1266738
Death Receptor Signaling R-HSA-73887
Epigenetic regulation of gene expression R-HSA-212165
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Regulation of PTEN gene transcription R-HSA-8943724
RNA Polymerase II Transcription R-HSA-73857
Regulation of MECP2 expression and activity R-HSA-9022692
Nervous system development R-HSA-9675108
Notch-HLH transcription pathway R-HSA-350054
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Negative epigenetic regulation of rRNA expression R-HSA-5250941
SUMOylation R-HSA-2990846
Post-translational protein modification R-HSA-597592
Transcriptional Regulation by MECP2 R-HSA-8986944
FOXO-mediated transcription R-HSA-9614085
Gene expression (Transcription) R-HSA-74160
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
RNA Polymerase I Transcription Initiation R-HSA-73762
Signaling by NOTCH R-HSA-157118
Signaling by ALK R-HSA-201556
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Chromatin organization R-HSA-4839726
Regulation of TP53 Activity R-HSA-5633007
SUMOylation of chromatin organization proteins R-HSA-4551638
RNA Polymerase I Transcription R-HSA-73864
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Factors involved in megakaryocyte development and platelet production R-HSA-983231
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Chromatin modifying enzymes R-HSA-3247509
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PTEN Regulation R-HSA-6807070
SARS-CoV Infections R-HSA-9679506
p75 NTR receptor-mediated signalling R-HSA-193704
HDACs deacetylate histones R-HSA-3214815
Hemostasis R-HSA-109582
Potential therapeutics for SARS R-HSA-9679191
Transcriptional Regulation by TP53 R-HSA-3700989
NoRC negatively regulates rRNA expression R-HSA-427413
Generic Transcription Pathway R-HSA-212436
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Potential therapeutics for SARS R-HSA-9679191
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 R-HSA-1980143
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
RNA Polymerase I Transcription R-HSA-73864
NoRC negatively regulates rRNA expression R-HSA-427413
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
PTEN Regulation R-HSA-6807070
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
RNA Polymerase I Promoter Clearance R-HSA-73854
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Signaling by NOTCH R-HSA-157118
Disease R-HSA-1643685
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Regulation of MECP2 expression and activity R-HSA-9022692
HDACs deacetylate histones R-HSA-3214815
MECP2 regulates neuronal receptors and channels R-HSA-9022699
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
Chromatin modifying enzymes R-HSA-3247509
Regulation of TP53 Activity R-HSA-5633007
FOXO-mediated transcription R-HSA-9614085
Developmental Biology R-HSA-1266738
Regulation of TP53 Activity through Acetylation R-HSA-6804758
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Chromatin organization R-HSA-4839726
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of PTEN gene transcription R-HSA-8943724
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Infectious disease R-HSA-5663205
Signaling by ALK R-HSA-201556
SUMOylation of chromatin organization proteins R-HSA-4551638
SARS-CoV Infections R-HSA-9679506
Hemostasis R-HSA-109582
Epigenetic regulation of gene expression R-HSA-212165
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by MECP2 R-HSA-8986944
PIP3 activates AKT signaling R-HSA-1257604
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nervous system development R-HSA-9675108
Signaling by NOTCH1 in Cancer R-HSA-2644603
Notch-HLH transcription pathway R-HSA-350054
p75 NTR receptor-mediated signalling R-HSA-193704
SUMOylation R-HSA-2990846
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase I Transcription Initiation R-HSA-73762
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN gene transcription R-HSA-8943724
NoRC negatively regulates rRNA expression R-HSA-427413
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Post-translational protein modification R-HSA-597592
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
PTEN Regulation R-HSA-6807070
Notch-HLH transcription pathway R-HSA-350054
Death Receptor Signaling R-HSA-73887
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Generic Transcription Pathway R-HSA-212436
HDACs deacetylate histones R-HSA-3214815
Intracellular signaling by second messengers R-HSA-9006925
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Epigenetic regulation of gene expression R-HSA-212165
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
RNA Polymerase I Promoter Clearance R-HSA-73854
Positive epigenetic regulation of rRNA expression R-HSA-5250913
p75 NTR receptor-mediated signalling R-HSA-193704
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Signaling by NOTCH1 in Cancer R-HSA-2644603
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Chromatin modifying enzymes R-HSA-3247509
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
RNA Polymerase I Transcription Initiation R-HSA-73762
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
FOXO-mediated transcription R-HSA-9614085
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Hemostasis R-HSA-109582
PIP3 activates AKT signaling R-HSA-1257604
Developmental Biology R-HSA-1266738
Chromatin organization R-HSA-4839726
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Potential therapeutics for SARS R-HSA-9679191
RNA Polymerase II Transcription R-HSA-73857
RNA Polymerase I Transcription R-HSA-73864
Gene expression (Transcription) R-HSA-74160
Factors involved in megakaryocyte development and platelet production R-HSA-983231
SUMOylation of chromatin organization proteins R-HSA-4551638
Regulation of MECP2 expression and activity R-HSA-9022692
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007
SUMOylation R-HSA-2990846
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional Regulation by MECP2 R-HSA-8986944
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Nervous system development R-HSA-9675108
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Signaling by ALK R-HSA-201556
SUMOylation R-HSA-2990846
Chromatin modifying enzymes R-HSA-3247509
Death Receptor Signaling R-HSA-73887
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 in Cancer R-HSA-2644603
SUMOylation of chromatin organization proteins R-HSA-4551638
Regulation of PTEN gene transcription R-HSA-8943724
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Signal Transduction R-HSA-162582
RNA Polymerase I Promoter Clearance R-HSA-73854
SARS-CoV Infections R-HSA-9679506
Regulation of TP53 Activity R-HSA-5633007
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Notch-HLH transcription pathway R-HSA-350054
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
RNA Polymerase I Transcription Initiation R-HSA-73762
PTEN Regulation R-HSA-6807070
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
RNA Polymerase I Transcription R-HSA-73864
Signaling by ALK R-HSA-201556
Regulation of TP53 Activity through Acetylation R-HSA-6804758
RNA Polymerase II Transcription R-HSA-73857
NoRC negatively regulates rRNA expression R-HSA-427413
Intracellular signaling by second messengers R-HSA-9006925
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Hemostasis R-HSA-109582
Nervous system development R-HSA-9675108
Chromatin organization R-HSA-4839726
HDACs deacetylate histones R-HSA-3214815
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Signaling by NOTCH1 R-HSA-1980143
Gene expression (Transcription) R-HSA-74160
p75 NTR receptor-mediated signalling R-HSA-193704
Generic Transcription Pathway R-HSA-212436
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Transcriptional Regulation by TP53 R-HSA-3700989
FOXO-mediated transcription R-HSA-9614085
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
PIP3 activates AKT signaling R-HSA-1257604
Epigenetic regulation of gene expression R-HSA-212165
Post-translational protein modification R-HSA-597592
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Potential therapeutics for SARS R-HSA-9679191
Regulation of MECP2 expression and activity R-HSA-9022692
Intracellular signaling by second messengers R-HSA-9006925
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Infectious disease R-HSA-5663205
p75 NTR receptor-mediated signalling R-HSA-193704
NoRC negatively regulates rRNA expression R-HSA-427413
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
PIP3 activates AKT signaling R-HSA-1257604
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Notch-HLH transcription pathway R-HSA-350054
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Transcriptional Regulation by MECP2 R-HSA-8986944
Signaling by NOTCH1 R-HSA-1980143
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
SUMOylation of chromatin organization proteins R-HSA-4551638
PTEN Regulation R-HSA-6807070
Signaling by ALK R-HSA-201556
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by TP53 R-HSA-3700989
Death Receptor Signaling R-HSA-73887
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
RNA Polymerase I Transcription Initiation R-HSA-73762
RNA Polymerase I Promoter Clearance R-HSA-73854
RNA Polymerase II Transcription R-HSA-73857
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
RNA Polymerase I Transcription R-HSA-73864
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity through Acetylation R-HSA-6804758
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Epigenetic regulation of gene expression R-HSA-212165
Chromatin organization R-HSA-4839726
SARS-CoV Infections R-HSA-9679506
HDACs deacetylate histones R-HSA-3214815
Potential therapeutics for SARS R-HSA-9679191
Chromatin modifying enzymes R-HSA-3247509
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulation of PTEN gene transcription R-HSA-8943724
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
FOXO-mediated transcription R-HSA-9614085
Generic Transcription Pathway R-HSA-212436
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Developmental Biology R-HSA-1266738
Regulation of MECP2 expression and activity R-HSA-9022692
RNA Polymerase I Transcription R-HSA-73864
RNA Polymerase I Transcription Initiation R-HSA-73762
Regulation of PTEN gene transcription R-HSA-8943724
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Activity R-HSA-5633007
Nervous system development R-HSA-9675108
NoRC negatively regulates rRNA expression R-HSA-427413
Chromatin organization R-HSA-4839726
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Negative epigenetic regulation of rRNA expression R-HSA-5250941
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
FOXO-mediated transcription R-HSA-9614085
Intracellular signaling by second messengers R-HSA-9006925
SUMOylation R-HSA-2990846
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ALK R-HSA-201556
Signaling by NOTCH1 in Cancer R-HSA-2644603
RNA Polymerase I Promoter Clearance R-HSA-73854
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Generic Transcription Pathway R-HSA-212436
Epigenetic regulation of gene expression R-HSA-212165
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Transcriptional Regulation by MECP2 R-HSA-8986944
HDACs deacetylate histones R-HSA-3214815
Regulation of MECP2 expression and activity R-HSA-9022692
Developmental Biology R-HSA-1266738
Hemostasis R-HSA-109582
PTEN Regulation R-HSA-6807070
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Chromatin modifying enzymes R-HSA-3247509
Death Receptor Signaling R-HSA-73887
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Infectious disease R-HSA-5663205
Notch-HLH transcription pathway R-HSA-350054
Gene expression (Transcription) R-HSA-74160
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation of chromatin organization proteins R-HSA-4551638
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
Disease R-HSA-1643685
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Notch-HLH transcription pathway R-HSA-350054
HDACs deacetylate histones R-HSA-3214815
Nervous system development R-HSA-9675108
RNA Polymerase I Transcription R-HSA-73864
Infectious disease R-HSA-5663205
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN gene transcription R-HSA-8943724
Chromatin modifying enzymes R-HSA-3247509
Transcriptional Regulation by MECP2 R-HSA-8986944
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Signaling by NOTCH1 R-HSA-1980143
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Death Receptor Signaling R-HSA-73887
FOXO-mediated transcription R-HSA-9614085
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
p75 NTR receptor-mediated signalling R-HSA-193704
SARS-CoV Infections R-HSA-9679506
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Epigenetic regulation of gene expression R-HSA-212165
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Generic Transcription Pathway R-HSA-212436
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Potential therapeutics for SARS R-HSA-9679191
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
RNA Polymerase I Transcription Initiation R-HSA-73762
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional Regulation by TP53 R-HSA-3700989
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
PTEN Regulation R-HSA-6807070
Chromatin organization R-HSA-4839726
NoRC negatively regulates rRNA expression R-HSA-427413
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase I Promoter Clearance R-HSA-73854
Signaling by ALK R-HSA-201556
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SUMOylation of chromatin organization proteins R-HSA-4551638
Signaling by NOTCH1 in Cancer R-HSA-2644603
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Signaling by NOTCH R-HSA-157118
Regulation of TP53 Activity R-HSA-5633007
Regulation of MECP2 expression and activity R-HSA-9022692
Hemostasis R-HSA-109582
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
FOXO-mediated transcription R-HSA-9614085
Chromatin organization R-HSA-4839726
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH1 in Cancer R-HSA-2644603
RNA Polymerase I Promoter Clearance R-HSA-73854
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Epigenetic regulation of gene expression R-HSA-212165
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Hemostasis R-HSA-109582
Regulation of TP53 Activity R-HSA-5633007
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
NoRC negatively regulates rRNA expression R-HSA-427413
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
SUMOylation of chromatin organization proteins R-HSA-4551638
Potential therapeutics for SARS R-HSA-9679191
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Signaling by ALK R-HSA-201556
RNA Polymerase I Transcription Initiation R-HSA-73762
Signaling by NOTCH1 R-HSA-1980143
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Notch-HLH transcription pathway R-HSA-350054
SUMOylation R-HSA-2990846
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
HDACs deacetylate histones R-HSA-3214815
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Disease R-HSA-1643685
Transcriptional Regulation by TP53 R-HSA-3700989
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Chromatin modifying enzymes R-HSA-3247509
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Death Receptor Signaling R-HSA-73887
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transcriptional Regulation by MECP2 R-HSA-8986944
Regulation of MECP2 expression and activity R-HSA-9022692
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
SARS-CoV Infections R-HSA-9679506
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
RNA Polymerase I Transcription R-HSA-73864
p75 NTR receptor-mediated signalling R-HSA-193704
Regulation of TP53 Activity R-HSA-5633007
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH R-HSA-157118
Transcriptional Regulation by MECP2 R-HSA-8986944
SUMOylation of chromatin organization proteins R-HSA-4551638
PIP3 activates AKT signaling R-HSA-1257604
SUMOylation R-HSA-2990846
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
Notch-HLH transcription pathway R-HSA-350054
Infectious disease R-HSA-5663205
Regulation of MECP2 expression and activity R-HSA-9022692
RNA Polymerase I Promoter Clearance R-HSA-73854
Post-translational protein modification R-HSA-597592
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RNA Polymerase I Transcription Initiation R-HSA-73762
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by NOTCH1 R-HSA-1980143
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Potential therapeutics for SARS R-HSA-9679191
Regulation of PTEN gene transcription R-HSA-8943724
NoRC negatively regulates rRNA expression R-HSA-427413
HDACs deacetylate histones R-HSA-3214815
p75 NTR receptor-mediated signalling R-HSA-193704
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
FOXO-mediated transcription R-HSA-9614085
Chromatin organization R-HSA-4839726
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by ALK R-HSA-201556
Death Receptor Signaling R-HSA-73887
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
PTEN Regulation R-HSA-6807070
Epigenetic regulation of gene expression R-HSA-212165
Positive epigenetic regulation of rRNA expression R-HSA-5250913
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Disease R-HSA-1643685
MECP2 regulates neuronal receptors and channels R-HSA-9022699
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Hemostasis R-HSA-109582
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Chromatin modifying enzymes R-HSA-3247509
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Potential therapeutics for SARS R-HSA-9679191
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
RNA Polymerase I Promoter Clearance R-HSA-73854
Nervous system development R-HSA-9675108
Chromatin organization R-HSA-4839726
Developmental Biology R-HSA-1266738
SUMOylation R-HSA-2990846
PIP3 activates AKT signaling R-HSA-1257604
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NoRC negatively regulates rRNA expression R-HSA-427413
Regulation of TP53 Activity R-HSA-5633007
FOXO-mediated transcription R-HSA-9614085
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Regulation of TP53 Activity through Acetylation R-HSA-6804758
SARS-CoV Infections R-HSA-9679506
Transcriptional Regulation by MECP2 R-HSA-8986944
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Signaling by NOTCH1 in Cancer R-HSA-2644603
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of MECP2 expression and activity R-HSA-9022692
RNA Polymerase I Transcription Initiation R-HSA-73762
SUMOylation of chromatin organization proteins R-HSA-4551638
Signaling by NOTCH1 R-HSA-1980143
Positive epigenetic regulation of rRNA expression R-HSA-5250913
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Epigenetic regulation of gene expression R-HSA-212165
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898
Death Receptor Signaling R-HSA-73887
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Infectious disease R-HSA-5663205
Chromatin modifying enzymes R-HSA-3247509
Signaling by ALK R-HSA-201556
Post-translational protein modification R-HSA-597592
Regulation of PTEN gene transcription R-HSA-8943724
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017
Metabolism of proteins R-HSA-392499
RNA Polymerase I Transcription R-HSA-73864
Negative epigenetic regulation of rRNA expression R-HSA-5250941
Generic Transcription Pathway R-HSA-212436
HDACs deacetylate histones R-HSA-3214815
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Notch-HLH transcription pathway R-HSA-350054
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hemostasis R-HSA-109582
MECP2 regulates neuronal receptors and channels R-HSA-9022699

Expression Atlas ENSG00000196591
NCBI gene (formerly Entrezgene) 3066
GeneCards 4853
HGNC Symbol HGNC:4853
MIM gene 605164
UniProtKB Gene Name Q92769
WikiGene 3066
Gene: HDAC5
Ensembl ID : ENSG00000108840
Description: histone deacetylase 5
Gene Synonyms: FLJ90614,KIAA0600,NY-CO-9
8 APIs:
194 Possible Orthologues:

Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Notch-HLH transcription pathway R-HSA-350054
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
PIP3 activates AKT signaling R-HSA-1257604
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PTEN Regulation R-HSA-6807070
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 R-HSA-1980143
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
Notch-HLH transcription pathway R-HSA-350054
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Gene expression (Transcription) R-HSA-74160
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Regulation of PTEN gene transcription R-HSA-8943724
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH1 in Cancer R-HSA-2644603
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NOTCH1 R-HSA-1980143
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Notch-HLH transcription pathway R-HSA-350054
Signal Transduction R-HSA-162582
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Regulation of PTEN gene transcription R-HSA-8943724
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signal Transduction R-HSA-162582
PTEN Regulation R-HSA-6807070
Signaling by NOTCH1 R-HSA-1980143
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Regulation of PTEN gene transcription R-HSA-8943724
Gene expression (Transcription) R-HSA-74160
Notch-HLH transcription pathway R-HSA-350054
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NOTCH1 R-HSA-1980143
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Notch-HLH transcription pathway R-HSA-350054
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 in Cancer R-HSA-2644603
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH1 in Cancer R-HSA-2644603
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Notch-HLH transcription pathway R-HSA-350054
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by NOTCH1 R-HSA-1980143
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH1 in Cancer R-HSA-2644603
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by NOTCH1 R-HSA-1980143
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH R-HSA-157118
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
RNA Polymerase II Transcription R-HSA-73857
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Notch-HLH transcription pathway R-HSA-350054
Regulation of PTEN gene transcription R-HSA-8943724
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
PTEN Regulation R-HSA-6807070
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH1 R-HSA-1980143
Notch-HLH transcription pathway R-HSA-350054
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH1 in Cancer R-HSA-2644603
PIP3 activates AKT signaling R-HSA-1257604
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN gene transcription R-HSA-8943724
Generic Transcription Pathway R-HSA-212436
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
PTEN Regulation R-HSA-6807070
Signaling by NOTCH1 R-HSA-1980143
Disease R-HSA-1643685
Signaling by NOTCH1 in Cancer R-HSA-2644603
Notch-HLH transcription pathway R-HSA-350054
Intracellular signaling by second messengers R-HSA-9006925
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Gene expression (Transcription) R-HSA-74160
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN gene transcription R-HSA-8943724
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Notch-HLH transcription pathway R-HSA-350054
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
PTEN Regulation R-HSA-6807070
Regulation of PTEN gene transcription R-HSA-8943724
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858

Expression Atlas ENSG00000108840
NCBI gene (formerly Entrezgene) 10014
GeneCards 14068
HGNC Symbol HGNC:14068
MIM gene 605315
UniProtKB Gene Name Q9UQL6
WikiGene 10014