Gene: PSMC6
Ensembl ID : ENSG00000100519
Description: proteasome 26S subunit, ATPase 6
Gene Synonyms: P42,RPT5
5 APIs:
229 Possible Orthologues:

DNA Replication R-HSA-69306
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
HIV Infection R-HSA-162906
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 family signaling R-HSA-446652
Assembly of the pre-replicative complex R-HSA-68867
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by NOTCH4 R-HSA-9013694
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
PCP/CE pathway R-HSA-4086400
Signaling by Interleukins R-HSA-449147
Beta-catenin independent WNT signaling R-HSA-3858494
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
SARS-CoV-1 Infection R-HSA-9678108
Cell Cycle, Mitotic R-HSA-69278
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G2-G2/M phases R-HSA-453274
HIV Infection R-HSA-162906
p53-Independent DNA Damage Response R-HSA-69610
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Separation of Sister Chromatids R-HSA-2467813
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of GLI2 by the proteasome R-HSA-5610783
Stabilization of p53 R-HSA-69541
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
S Phase R-HSA-69242
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Disorders of transmembrane transporters R-HSA-5619115
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream TCR signaling R-HSA-202424
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Nuclear events mediated by NFE2L2 R-HSA-9759194
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog 'off' state R-HSA-5610787
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX3 R-HSA-8878159
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RNA Polymerase II Transcription R-HSA-73857
Neddylation R-HSA-8951664
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G2/M Checkpoints R-HSA-69481
ABC-family proteins mediated transport R-HSA-382556
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
Regulation of PTEN stability and activity R-HSA-8948751
Innate Immune System R-HSA-168249
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK family signaling cascades R-HSA-5683057
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to chemical stress R-HSA-9711123
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX2 R-HSA-8878166
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Host Interactions of HIV factors R-HSA-162909
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
SARS-CoV-1-host interactions R-HSA-9692914
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Orc1 removal from chromatin R-HSA-68949
Intracellular signaling by second messengers R-HSA-9006925
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
ABC transporter disorders R-HSA-5619084
Developmental Biology R-HSA-1266738
SARS-CoV Infections R-HSA-9679506
G1/S Transition R-HSA-69206
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
Ub-specific processing proteases R-HSA-5689880
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of Apoptosis R-HSA-169911
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of AXIN R-HSA-4641257
Regulation of expression of SLITs and ROBOs R-HSA-9010553
S Phase R-HSA-69242
p53-Independent DNA Damage Response R-HSA-69610
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle R-HSA-1640170
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Vpu mediated degradation of CD4 R-HSA-180534
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Cyclin E associated events during G1/S transition R-HSA-69202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC transporter disorders R-HSA-5619084
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Metabolism of proteins R-HSA-392499
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Neddylation R-HSA-8951664
SARS-CoV-1-host interactions R-HSA-9692914
UCH proteinases R-HSA-5689603
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of Apoptosis R-HSA-169911
Regulation of PTEN stability and activity R-HSA-8948751
Synthesis of DNA R-HSA-69239
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Intracellular signaling by second messengers R-HSA-9006925
G2/M Transition R-HSA-69275
RNA Polymerase II Transcription R-HSA-73857
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of amino acids and derivatives R-HSA-71291
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants are degraded by ERAD R-HSA-5362768
Developmental Biology R-HSA-1266738
Post-translational protein modification R-HSA-597592
Separation of Sister Chromatids R-HSA-2467813
MAPK family signaling cascades R-HSA-5683057
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Negative regulation of NOTCH4 signaling R-HSA-9604323
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Degradation of GLI1 by the proteasome R-HSA-5610780
Infectious disease R-HSA-5663205
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
ABC-family proteins mediated transport R-HSA-382556
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by ROBO receptors R-HSA-376176
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream TCR signaling R-HSA-202424
Axon guidance R-HSA-422475
Cellular response to hypoxia R-HSA-1234174
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Disease R-HSA-1643685
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1 DNA Damage Response R-HSA-69563
SARS-CoV Infections R-HSA-9679506
SARS-CoV-1 Infection R-HSA-9678108
HIV Infection R-HSA-162906
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G2-G2/M phases R-HSA-453274
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants abrogate ligand secretion R-HSA-5387390
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
PTEN Regulation R-HSA-6807070
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Assembly of the pre-replicative complex R-HSA-68867
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
Metabolism of polyamines R-HSA-351202
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Vpu mediated degradation of CD4 R-HSA-180534
Axon guidance R-HSA-422475
Cellular responses to stress R-HSA-2262752
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 signaling R-HSA-9020702
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Innate Immune System R-HSA-168249
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Mitotic G2-G2/M phases R-HSA-453274
p53-Independent DNA Damage Response R-HSA-69610
DNA Replication R-HSA-69306
Metabolism of amino acids and derivatives R-HSA-71291
SARS-CoV-1 Infection R-HSA-9678108
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hedgehog 'off' state R-HSA-5610787
G1/S Transition R-HSA-69206
Infectious disease R-HSA-5663205
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of beta-catenin by the destruction complex R-HSA-195253
Developmental Biology R-HSA-1266738
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SARS-CoV Infections R-HSA-9679506
Signaling by Hedgehog R-HSA-5358351
Asymmetric localization of PCP proteins R-HSA-4608870
Stabilization of p53 R-HSA-69541
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Interleukin-1 family signaling R-HSA-446652
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transport of small molecules R-HSA-382551
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by WNT R-HSA-195721
HIV Infection R-HSA-162906
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Hh mutants abrogate ligand secretion R-HSA-5387390
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Replication Pre-Initiation R-HSA-69002
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of RNA R-HSA-8953854
Post-translational protein modification R-HSA-597592
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Activation of NF-kappaB in B cells R-HSA-1169091
KEAP1-NFE2L2 pathway R-HSA-9755511
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI2 by the proteasome R-HSA-5610783
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Degradation of DVL R-HSA-4641258
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Beta-catenin independent WNT signaling R-HSA-3858494
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
Deubiquitination R-HSA-5688426
Generic Transcription Pathway R-HSA-212436
Degradation of AXIN R-HSA-4641257
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Programmed Cell Death R-HSA-5357801
Apoptosis R-HSA-109581
RAF/MAP kinase cascade R-HSA-5673001
CLEC7A (Dectin-1) signaling R-HSA-5607764
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of mitotic cell cycle R-HSA-453276
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Cell Cycle, Mitotic R-HSA-69278
Infectious disease R-HSA-5663205
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Post-translational protein modification R-HSA-597592
Degradation of AXIN R-HSA-4641257
Regulation of RAS by GAPs R-HSA-5658442
Orc1 removal from chromatin R-HSA-68949
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Adaptive Immune System R-HSA-1280218
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
S Phase R-HSA-69242
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication R-HSA-69306
Asymmetric localization of PCP proteins R-HSA-4608870
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of proteins R-HSA-392499
SARS-CoV-1 Infection R-HSA-9678108
Cellular responses to stimuli R-HSA-8953897
Signaling by NOTCH R-HSA-157118
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Immune System R-HSA-168256
MAPK6/MAPK4 signaling R-HSA-5687128
Synthesis of DNA R-HSA-69239
Cellular response to hypoxia R-HSA-1234174
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Independent DNA Damage Response R-HSA-69610
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle R-HSA-1640170
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication Pre-Initiation R-HSA-69002
Nuclear events mediated by NFE2L2 R-HSA-9759194
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI1 by the proteasome R-HSA-5610780
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
TCR signaling R-HSA-202403
Interleukin-1 signaling R-HSA-9020702
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signal Transduction R-HSA-162582
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of Apoptosis R-HSA-169911
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Developmental Biology R-HSA-1266738
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Generic Transcription Pathway R-HSA-212436
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK1/MAPK3 signaling R-HSA-5684996
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cyclin E associated events during G1/S transition R-HSA-69202
M Phase R-HSA-68886
Innate Immune System R-HSA-168249
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'on' state R-HSA-5632684
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
SARS-CoV Infections R-HSA-9679506
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
PCP/CE pathway R-HSA-4086400
G1/S Transition R-HSA-69206
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
Negative regulation of NOTCH4 signaling R-HSA-9604323
SARS-CoV-1-host interactions R-HSA-9692914
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC-family proteins mediated transport R-HSA-382556
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
Cell Cycle, Mitotic R-HSA-69278
Nervous system development R-HSA-9675108
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX2 expression and activity R-HSA-8939902
Transport of small molecules R-HSA-382551
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX3 expression and activity R-HSA-8941858
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
CLEC7A (Dectin-1) signaling R-HSA-5607764
Gene expression (Transcription) R-HSA-74160
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
Hedgehog ligand biogenesis R-HSA-5358346
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of amino acids and derivatives R-HSA-71291
Switching of origins to a post-replicative state R-HSA-69052
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
UCH proteinases R-HSA-5689603
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
Infectious disease R-HSA-5663205
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stress R-HSA-2262752
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
PCP/CE pathway R-HSA-4086400
Degradation of beta-catenin by the destruction complex R-HSA-195253
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
p53-Dependent G1 DNA Damage Response R-HSA-69563
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of DVL R-HSA-4641258
Signaling by ROBO receptors R-HSA-376176
Regulation of mitotic cell cycle R-HSA-453276
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Vif-mediated degradation of APOBEC3G R-HSA-180585
Metabolism of polyamines R-HSA-351202
Signaling by NOTCH R-HSA-157118
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hedgehog 'off' state R-HSA-5610787
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants are degraded by ERAD R-HSA-5362768
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Interleukin-1 signaling R-HSA-9020702
Ub-specific processing proteases R-HSA-5689880
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Checkpoints R-HSA-69481
SARS-CoV-1 Infection R-HSA-9678108
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
DNA Replication Pre-Initiation R-HSA-69002
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FCERI mediated NF-kB activation R-HSA-2871837
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disorders of transmembrane transporters R-HSA-5619115
SARS-CoV-1-host interactions R-HSA-9692914
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Adaptive Immune System R-HSA-1280218
HIV Infection R-HSA-162906
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
SARS-CoV Infections R-HSA-9679506
ER-Phagosome pathway R-HSA-1236974
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
PTEN Regulation R-HSA-6807070
Metabolism of RNA R-HSA-8953854
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Synthesis of DNA R-HSA-69239
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Vpu mediated degradation of CD4 R-HSA-180534
Activation of NF-kappaB in B cells R-HSA-1169091
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism R-HSA-1430728
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of mitotic cell cycle R-HSA-453276
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle, Mitotic R-HSA-69278
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
Adaptive Immune System R-HSA-1280218
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RAF/MAP kinase cascade R-HSA-5673001
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
Switching of origins to a post-replicative state R-HSA-69052
UCH proteinases R-HSA-5689603
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transcriptional regulation by RUNX1 R-HSA-8878171
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants abrogate ligand secretion R-HSA-5387390
TCF dependent signaling in response to WNT R-HSA-201681
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
KEAP1-NFE2L2 pathway R-HSA-9755511
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI2 by the proteasome R-HSA-5610783
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Interleukins R-HSA-449147
p53-Independent DNA Damage Response R-HSA-69610
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular responses to stimuli R-HSA-8953897
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to chemical stress R-HSA-9711123
Generic Transcription Pathway R-HSA-212436
Separation of Sister Chromatids R-HSA-2467813
Axon guidance R-HSA-422475
SARS-CoV-1 Infection R-HSA-9678108
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cytokine Signaling in Immune system R-HSA-1280215
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Disorders of transmembrane transporters R-HSA-5619115
ABC transporter disorders R-HSA-5619084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Regulation of Apoptosis R-HSA-169911
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PTEN Regulation R-HSA-6807070
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
HIV Infection R-HSA-162906
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SARS-CoV Infections R-HSA-9679506
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Hedgehog R-HSA-5358351
Ub-specific processing proteases R-HSA-5689880
Synthesis of DNA R-HSA-69239
Asymmetric localization of PCP proteins R-HSA-4608870
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
Hh mutants are degraded by ERAD R-HSA-5362768
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
Regulation of Apoptosis R-HSA-169911
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Downstream TCR signaling R-HSA-202424
Vif-mediated degradation of APOBEC3G R-HSA-180585
Separation of Sister Chromatids R-HSA-2467813
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic Metaphase and Anaphase R-HSA-2555396
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by Hedgehog R-HSA-5358351
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Host Interactions of HIV factors R-HSA-162909
Cytokine Signaling in Immune system R-HSA-1280215
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hh mutants abrogate ligand secretion R-HSA-5387390
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hh mutants are degraded by ERAD R-HSA-5362768
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Gene expression (Transcription) R-HSA-74160
RAF/MAP kinase cascade R-HSA-5673001
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
Developmental Biology R-HSA-1266738
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK family signaling cascades R-HSA-5683057
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Axon guidance R-HSA-422475
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
C-type lectin receptors (CLRs) R-HSA-5621481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PIP3 activates AKT signaling R-HSA-1257604
Signaling by WNT R-HSA-195721
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of PTEN stability and activity R-HSA-8948751
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Interleukin-1 signaling R-HSA-9020702
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
p53-Independent DNA Damage Response R-HSA-69610
Assembly of the pre-replicative complex R-HSA-68867
Infectious disease R-HSA-5663205
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
G1/S DNA Damage Checkpoints R-HSA-69615
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stimuli R-HSA-8953897
Mitotic G2-G2/M phases R-HSA-453274
ABC-family proteins mediated transport R-HSA-382556
M Phase R-HSA-68886
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Checkpoints R-HSA-69481
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TCR signaling R-HSA-202403
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
SARS-CoV Infections R-HSA-9679506
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH R-HSA-157118
SARS-CoV-1 Infection R-HSA-9678108
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional regulation by RUNX2 R-HSA-8878166
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Stabilization of p53 R-HSA-69541
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by Interleukins R-HSA-449147
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Asymmetric localization of PCP proteins R-HSA-4608870
CLEC7A (Dectin-1) signaling R-HSA-5607764
Neddylation R-HSA-8951664
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Post-translational protein modification R-HSA-597592
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Antigen processing-Cross presentation R-HSA-1236975
Cellular responses to stress R-HSA-2262752
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PTEN Regulation R-HSA-6807070
Orc1 removal from chromatin R-HSA-68949
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Cytokine Signaling in Immune system R-HSA-1280215
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
TCR signaling R-HSA-202403
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Synthesis of DNA R-HSA-69239
Signaling by ROBO receptors R-HSA-376176
Downstream TCR signaling R-HSA-202424
S Phase R-HSA-69242
Mitotic G2-G2/M phases R-HSA-453274
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
Regulation of mitotic cell cycle R-HSA-453276
Adaptive Immune System R-HSA-1280218
Nervous system development R-HSA-9675108
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Signaling by WNT R-HSA-195721
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism R-HSA-1430728
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
RAF/MAP kinase cascade R-HSA-5673001
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RNA Polymerase II Transcription R-HSA-73857
Stabilization of p53 R-HSA-69541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
PCP/CE pathway R-HSA-4086400
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 signaling R-HSA-9020702
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Assembly of the pre-replicative complex R-HSA-68867
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle Checkpoints R-HSA-69620
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Axon guidance R-HSA-422475
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by NOTCH4 R-HSA-9013694
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Gene expression (Transcription) R-HSA-74160
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Infectious disease R-HSA-5663205
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Intracellular signaling by second messengers R-HSA-9006925
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ABC transporter disorders R-HSA-5619084
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle, Mitotic R-HSA-69278
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Developmental Biology R-HSA-1266738
SARS-CoV-1 Infection R-HSA-9678108
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
Nervous system development R-HSA-9675108
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of mitotic cell cycle R-HSA-453276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by ROBO receptors R-HSA-376176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
PCP/CE pathway R-HSA-4086400
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX1 R-HSA-8878171
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Stabilization of p53 R-HSA-69541
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by WNT R-HSA-195721
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic G2-G2/M phases R-HSA-453274
Degradation of GLI1 by the proteasome R-HSA-5610780
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Beta-catenin independent WNT signaling R-HSA-3858494
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of RAS by GAPs R-HSA-5658442
Signaling by NOTCH R-HSA-157118
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Innate Immune System R-HSA-168249
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PTEN Regulation R-HSA-6807070
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Cellular response to chemical stress R-HSA-9711123
Disorders of transmembrane transporters R-HSA-5619115
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transport of small molecules R-HSA-382551
Ub-specific processing proteases R-HSA-5689880
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of DVL R-HSA-4641258
TCF dependent signaling in response to WNT R-HSA-201681
Deubiquitination R-HSA-5688426
Neddylation R-HSA-8951664
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 signaling R-HSA-9020702
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCR signaling R-HSA-202403
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
FCERI mediated NF-kB activation R-HSA-2871837
Adaptive Immune System R-HSA-1280218
Hedgehog 'off' state R-HSA-5610787
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
PIP3 activates AKT signaling R-HSA-1257604
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Hh mutants are degraded by ERAD R-HSA-5362768
Interleukin-1 family signaling R-HSA-446652
Asymmetric localization of PCP proteins R-HSA-4608870
SARS-CoV-1 Infection R-HSA-9678108
DNA Replication R-HSA-69306
M Phase R-HSA-68886
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
SARS-CoV-1-host interactions R-HSA-9692914
Apoptosis R-HSA-109581
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
UCH proteinases R-HSA-5689603
Degradation of GLI2 by the proteasome R-HSA-5610783
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
SARS-CoV Infections R-HSA-9679506
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1 DNA Damage Response R-HSA-69563
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of AXIN R-HSA-4641257
Programmed Cell Death R-HSA-5357801
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Immune System R-HSA-168256
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Hedgehog R-HSA-5358351
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Programmed Cell Death R-HSA-5357801
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of beta-catenin by the destruction complex R-HSA-195253
S Phase R-HSA-69242
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
Transcriptional regulation by RUNX1 R-HSA-8878171
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Disorders of transmembrane transporters R-HSA-5619115
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by Hedgehog R-HSA-5358351
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Vpu mediated degradation of CD4 R-HSA-180534
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of amino acids and derivatives R-HSA-71291
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stress R-HSA-2262752
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Mitotic Anaphase R-HSA-68882
Mitotic G2-G2/M phases R-HSA-453274
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Generic Transcription Pathway R-HSA-212436
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
Regulation of mitotic cell cycle R-HSA-453276
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
PIP3 activates AKT signaling R-HSA-1257604
Post-translational protein modification R-HSA-597592
Transport of small molecules R-HSA-382551
Beta-catenin independent WNT signaling R-HSA-3858494
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nuclear events mediated by NFE2L2 R-HSA-9759194
Immune System R-HSA-168256
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
Metabolism of polyamines R-HSA-351202
SARS-CoV-1 Infection R-HSA-9678108
DNA Replication Pre-Initiation R-HSA-69002
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
G1/S Transition R-HSA-69206
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RAF/MAP kinase cascade R-HSA-5673001
Orc1 removal from chromatin R-HSA-68949
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Checkpoints R-HSA-69481
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
Neddylation R-HSA-8951664
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCR signaling R-HSA-202403
Antigen processing-Cross presentation R-HSA-1236975
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
Interleukin-1 signaling R-HSA-9020702
UCH proteinases R-HSA-5689603
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK family signaling cascades R-HSA-5683057
Axon guidance R-HSA-422475
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Metabolism of proteins R-HSA-392499
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX2 expression and activity R-HSA-8939902
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
SARS-CoV-1-host interactions R-HSA-9692914
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
M Phase R-HSA-68886
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Stabilization of p53 R-HSA-69541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of proteins R-HSA-392499
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Hh mutants are degraded by ERAD R-HSA-5362768
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SARS-CoV-1 Infection R-HSA-9678108
Metabolism of amino acids and derivatives R-HSA-71291
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
M Phase R-HSA-68886
Interleukin-1 signaling R-HSA-9020702
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
Degradation of GLI2 by the proteasome R-HSA-5610783
Degradation of AXIN R-HSA-4641257
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
FCERI mediated NF-kB activation R-HSA-2871837
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants abrogate ligand secretion R-HSA-5387390
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
Stabilization of p53 R-HSA-69541
Interleukin-1 family signaling R-HSA-446652
Mitotic G2-G2/M phases R-HSA-453274
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Cell Cycle R-HSA-1640170
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Host Interactions of HIV factors R-HSA-162909
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream TCR signaling R-HSA-202424
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Axon guidance R-HSA-422475
SARS-CoV-1-host interactions R-HSA-9692914
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH4 R-HSA-9013694
p53-Independent DNA Damage Response R-HSA-69610
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Vif-mediated degradation of APOBEC3G R-HSA-180585
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX2 expression and activity R-HSA-8939902
Transport of small molecules R-HSA-382551
G2/M Transition R-HSA-69275
RAF/MAP kinase cascade R-HSA-5673001
ABC-family proteins mediated transport R-HSA-382556
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of polyamines R-HSA-351202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic G1 phase and G1/S transition R-HSA-453279
Negative regulation of NOTCH4 signaling R-HSA-9604323
Assembly of the pre-replicative complex R-HSA-68867
SARS-CoV Infections R-HSA-9679506
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCF dependent signaling in response to WNT R-HSA-201681
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
TCR signaling R-HSA-202403
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular response to hypoxia R-HSA-1234174
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Mitotic Metaphase and Anaphase R-HSA-2555396
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603

Expression Atlas ENSG00000100519
NCBI gene (formerly Entrezgene) 5706
GeneCards 9553
HGNC Symbol HGNC:9553
MIM gene 602708
UniProtKB Gene Name P62333
WikiGene 5706
Gene: NPR2
Ensembl ID : ENSG00000159899
Description: natriuretic peptide receptor 2
Gene Synonyms: AMDM,ANPB,ANPRB,GC-B,GUCY2B,NPRB
1 APIs:
260 Possible Orthologues:

Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Cardiac conduction R-HSA-5576891
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768

Expression Atlas ENSG00000159899
NCBI gene (formerly Entrezgene) 4882
GeneCards 7944
HGNC Symbol HGNC:7944
MIM gene 108961
MIM morbid 616255
UniProtKB Gene Name P20594
WikiGene 4882
Gene: KLKB1
Ensembl ID : ENSG00000164344
Description: kallikrein B1
Gene Synonyms: KLK3
6 APIs:
209 Possible Orthologues:

Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Diseases of hemostasis R-HSA-9671793
Degradation of the extracellular matrix R-HSA-1474228
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor XII causes hereditary angioedema R-HSA-9657688
Hemostasis R-HSA-109582
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Extracellular matrix organization R-HSA-1474244
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Disease R-HSA-1643685
Degradation of the extracellular matrix R-HSA-1474228
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Activation of Matrix Metalloproteinases R-HSA-1592389
Activation of Matrix Metalloproteinases R-HSA-1592389
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor XII causes hereditary angioedema R-HSA-9657688
Degradation of the extracellular matrix R-HSA-1474228
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective factor XII causes hereditary angioedema R-HSA-9657688
Disease R-HSA-1643685
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Diseases of hemostasis R-HSA-9671793
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Degradation of the extracellular matrix R-HSA-1474228
Degradation of the extracellular matrix R-HSA-1474228
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Activation of Matrix Metalloproteinases R-HSA-1592389
Defective factor XII causes hereditary angioedema R-HSA-9657688

Expression Atlas ENSG00000164344
LRG display in Ensembl gene LRG_565
NCBI gene (formerly Entrezgene) 3818
GeneCards 6371
HGNC Symbol HGNC:6371
MIM gene 229000
MIM morbid 612423
UniProtKB Gene Name E9PBC5
WikiGene 3818
Gene: XDH
Ensembl ID : ENSG00000158125
Description: xanthine dehydrogenase
Gene Synonyms: XO,XOR
6 APIs:
210 Possible Orthologues:

Nucleotide catabolism R-HSA-8956319
Butyrophilin (BTN) family interactions R-HSA-8851680
Azathioprine ADME R-HSA-9748787
Metabolism of nucleotides R-HSA-15869
Drug ADME R-HSA-9748784
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
Purine catabolism R-HSA-74259
Azathioprine ADME R-HSA-9748787
Adaptive Immune System R-HSA-1280218
Nucleotide catabolism R-HSA-8956319
Immune System R-HSA-168256
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Butyrophilin (BTN) family interactions R-HSA-8851680
Drug ADME R-HSA-9748784
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Drug ADME R-HSA-9748784
Butyrophilin (BTN) family interactions R-HSA-8851680
Immune System R-HSA-168256
Purine catabolism R-HSA-74259
Metabolism of nucleotides R-HSA-15869
Adaptive Immune System R-HSA-1280218
Azathioprine ADME R-HSA-9748787
Nucleotide catabolism R-HSA-8956319
Adaptive Immune System R-HSA-1280218
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Drug ADME R-HSA-9748784
Purine catabolism R-HSA-74259
Butyrophilin (BTN) family interactions R-HSA-8851680
Azathioprine ADME R-HSA-9748787
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Azathioprine ADME R-HSA-9748787
Purine catabolism R-HSA-74259
Butyrophilin (BTN) family interactions R-HSA-8851680
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Drug ADME R-HSA-9748784
Adaptive Immune System R-HSA-1280218
Azathioprine ADME R-HSA-9748787
Butyrophilin (BTN) family interactions R-HSA-8851680
Immune System R-HSA-168256
Metabolism of nucleotides R-HSA-15869
Drug ADME R-HSA-9748784
Nucleotide catabolism R-HSA-8956319
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Immune System R-HSA-168256
Nucleotide catabolism R-HSA-8956319
Adaptive Immune System R-HSA-1280218
Purine catabolism R-HSA-74259
Drug ADME R-HSA-9748784
Metabolism R-HSA-1430728
Azathioprine ADME R-HSA-9748787
Butyrophilin (BTN) family interactions R-HSA-8851680
Immune System R-HSA-168256
Azathioprine ADME R-HSA-9748787
Butyrophilin (BTN) family interactions R-HSA-8851680
Drug ADME R-HSA-9748784
Adaptive Immune System R-HSA-1280218
Nucleotide catabolism R-HSA-8956319
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Butyrophilin (BTN) family interactions R-HSA-8851680
Metabolism of nucleotides R-HSA-15869
Adaptive Immune System R-HSA-1280218
Drug ADME R-HSA-9748784
Nucleotide catabolism R-HSA-8956319
Immune System R-HSA-168256
Azathioprine ADME R-HSA-9748787
Purine catabolism R-HSA-74259
Purine catabolism R-HSA-74259
Adaptive Immune System R-HSA-1280218
Drug ADME R-HSA-9748784
Butyrophilin (BTN) family interactions R-HSA-8851680
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Azathioprine ADME R-HSA-9748787
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Drug ADME R-HSA-9748784
Azathioprine ADME R-HSA-9748787
Adaptive Immune System R-HSA-1280218
Butyrophilin (BTN) family interactions R-HSA-8851680
Purine catabolism R-HSA-74259

Expression Atlas ENSG00000158125
NCBI gene (formerly Entrezgene) 7498
GeneCards 12805
HGNC Symbol HGNC:12805
MIM gene 607633
MIM morbid 278300
UniProtKB Gene Name P47989
WikiGene 7498
Gene: HPD
Ensembl ID : ENSG00000158104
Description: 4-hydroxyphenylpyruvate dioxygenase
Gene Synonyms: 4-HPPD,4HPPD,GLOD3,PPD
1 APIs:
207 Possible Orthologues:

Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism of amino acids and derivatives R-HSA-71291
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728
Tyrosine catabolism R-HSA-8963684
Metabolism R-HSA-1430728
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Tyrosine catabolism R-HSA-8963684
Tyrosine catabolism R-HSA-8963684
Metabolism of amino acids and derivatives R-HSA-71291
Phenylalanine and tyrosine metabolism R-HSA-8963691
Metabolism R-HSA-1430728

Expression Atlas ENSG00000158104
NCBI gene (formerly Entrezgene) 3242
GeneCards 5147
HGNC Symbol HGNC:5147
MIM gene 609695
MIM morbid 276710
UniProtKB Gene Name A0A0B4J1R4
WikiGene 3242
Gene: FGFR2
Ensembl ID : ENSG00000066468
Description: fibroblast growth factor receptor 2
Gene Synonyms: BEK,CD332,CEK3,CFD1,ECT1,JWS,K-SAM,KGFR,TK14,TK25
27 APIs:
218 Possible Orthologues:

Activated point mutants of FGFR2 R-HSA-2033519
PI3K Cascade R-HSA-109704
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR2c ligand binding and activation R-HSA-190375
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR in disease R-HSA-1226099
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Insulin receptor R-HSA-74752
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by FGFR2 R-HSA-5654738
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
FGFR2 mutant receptor activation R-HSA-1839126
Insulin receptor signalling cascade R-HSA-74751
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Disease R-HSA-1643685
Signaling by FGFR2 fusions R-HSA-8853333
IRS-mediated signalling R-HSA-112399
Signaling by FGFR2 in disease R-HSA-5655253
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
Insulin receptor signalling cascade R-HSA-74751
FGFR2 ligand binding and activation R-HSA-190241
FGFR2b ligand binding and activation R-HSA-190377
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Downstream signaling of activated FGFR2 R-HSA-5654696
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR R-HSA-190236
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR2 signaling R-HSA-5654727
Activated point mutants of FGFR2 R-HSA-2033519
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
FGFR2 mutant receptor activation R-HSA-1839126
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by FGFR2 IIIa TM R-HSA-8851708
IRS-related events triggered by IGF1R R-HSA-2428928
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2 alternative splicing R-HSA-6803529
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Activated point mutants of FGFR2 R-HSA-2033519
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2 alternative splicing R-HSA-6803529
FGFR2c ligand binding and activation R-HSA-190375
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by FGFR2 IIIa TM R-HSA-8851708
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 amplification mutants R-HSA-2023837
FGFR2 ligand binding and activation R-HSA-190241
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 mutant receptor activation R-HSA-1839126
PI3K Cascade R-HSA-109704
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
FGFR2b ligand binding and activation R-HSA-190377
Disease R-HSA-1643685
Signaling by Insulin receptor R-HSA-74752
PI3K/AKT Signaling in Cancer R-HSA-2219528
Insulin receptor signalling cascade R-HSA-74751
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR2 in disease R-HSA-5655253
RAF/MAP kinase cascade R-HSA-5673001
FRS-mediated FGFR2 signaling R-HSA-5654700
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FGFR2 ligand binding and activation R-HSA-190241
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2c ligand binding and activation R-HSA-190375
Signaling by FGFR R-HSA-190236
Downstream signaling of activated FGFR2 R-HSA-5654696
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
IRS-mediated signalling R-HSA-112399
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR2 R-HSA-5654738
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
SHC-mediated cascade:FGFR2 R-HSA-5654699
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FGFR2b ligand binding and activation R-HSA-190377
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR2 R-HSA-5654695
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR2 IIIa TM R-HSA-8851708
FGFR2 ligand binding and activation R-HSA-190241
PI3K Cascade R-HSA-109704
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 in disease R-HSA-5655253
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2b ligand binding and activation R-HSA-190377
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 fusions R-HSA-8853333
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by FGFR in disease R-HSA-1226099
FGFR2c ligand binding and activation R-HSA-190375
RAF/MAP kinase cascade R-HSA-5673001
PI3K/AKT Signaling in Cancer R-HSA-2219528
SHC-mediated cascade:FGFR2 R-HSA-5654699
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
Disease R-HSA-1643685
IRS-related events triggered by IGF1R R-HSA-2428928
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR2 alternative splicing R-HSA-6803529
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
IGF1R signaling cascade R-HSA-2428924
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by FGFR2 in disease R-HSA-5655253
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 amplification mutants R-HSA-2023837
IRS-related events triggered by IGF1R R-HSA-2428928
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF/MAP kinase cascade R-HSA-5673001
IRS-mediated signalling R-HSA-112399
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by FGFR2 IIIa TM R-HSA-8851708
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signal Transduction R-HSA-162582
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI3K Cascade R-HSA-109704
MAPK family signaling cascades R-HSA-5683057
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Disease R-HSA-1643685
Downstream signaling of activated FGFR2 R-HSA-5654696
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR2 signaling R-HSA-5654700
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2b ligand binding and activation R-HSA-190377
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Insulin receptor signalling cascade R-HSA-74751
IGF1R signaling cascade R-HSA-2428924
PIP3 activates AKT signaling R-HSA-1257604
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Insulin receptor R-HSA-74752
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR R-HSA-190236
Signaling by FGFR2 amplification mutants R-HSA-2023837
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 mutant receptor activation R-HSA-1839126
Signal Transduction R-HSA-162582
FRS-mediated FGFR2 signaling R-HSA-5654700
IRS-mediated signalling R-HSA-112399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR in disease R-HSA-1226099
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Negative regulation of FGFR2 signaling R-HSA-5654727
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
FGFR2c ligand binding and activation R-HSA-190375
SHC-mediated cascade:FGFR2 R-HSA-5654699
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
FGFR2 ligand binding and activation R-HSA-190241
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR2 alternative splicing R-HSA-6803529
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
Insulin receptor signalling cascade R-HSA-74751
FGFR2b ligand binding and activation R-HSA-190377
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IGF1R signaling cascade R-HSA-2428924
Activated point mutants of FGFR2 R-HSA-2033519
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 amplification mutants R-HSA-2023837
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
SHC-mediated cascade:FGFR2 R-HSA-5654699
PIP3 activates AKT signaling R-HSA-1257604
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by FGFR2 fusions R-HSA-8853333
Downstream signaling of activated FGFR2 R-HSA-5654696
FGFR2c ligand binding and activation R-HSA-190375
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR2 IIIa TM R-HSA-8851708
Disease R-HSA-1643685
FGFR2 ligand binding and activation R-HSA-190241
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR2 R-HSA-5654695
FGFR2b ligand binding and activation R-HSA-190377
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR2 in disease R-HSA-5655253
IRS-mediated signalling R-HSA-112399
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR in disease R-HSA-1226099
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
FGFR2 alternative splicing R-HSA-6803529
Signal Transduction R-HSA-162582
FGFR2 mutant receptor activation R-HSA-1839126
FRS-mediated FGFR2 signaling R-HSA-5654700
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 in disease R-HSA-5655253
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by FGFR2 amplification mutants R-HSA-2023837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR in disease R-HSA-1226099
Disease R-HSA-1643685
Negative regulation of FGFR2 signaling R-HSA-5654727
PIP3 activates AKT signaling R-HSA-1257604
FGFR2 mutant receptor activation R-HSA-1839126
Signaling by FGFR2 IIIa TM R-HSA-8851708
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
FGFR2b ligand binding and activation R-HSA-190377
IRS-mediated signalling R-HSA-112399
FGFR2c ligand binding and activation R-HSA-190375
IGF1R signaling cascade R-HSA-2428924
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
IRS-related events triggered by IGF1R R-HSA-2428928
PI3K Cascade R-HSA-109704
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Insulin receptor R-HSA-74752
PI-3K cascade:FGFR2 R-HSA-5654695
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by FGFR2 fusions R-HSA-8853333
FGFR2 ligand binding and activation R-HSA-190241
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 R-HSA-5654738
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Activated point mutants of FGFR2 R-HSA-2033519
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2 alternative splicing R-HSA-6803529
Signaling by FGFR2 IIIa TM R-HSA-8851708
SHC-mediated cascade:FGFR2 R-HSA-5654699
FGFR2b ligand binding and activation R-HSA-190377
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR2 in disease R-HSA-5655253
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
FGFR2c ligand binding and activation R-HSA-190375
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR2 fusions R-HSA-8853333
Negative regulation of FGFR2 signaling R-HSA-5654727
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR R-HSA-190236
Activated point mutants of FGFR2 R-HSA-2033519
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
PI-3K cascade:FGFR2 R-HSA-5654695
MAPK1/MAPK3 signaling R-HSA-5684996
FRS-mediated FGFR2 signaling R-HSA-5654700
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR2 amplification mutants R-HSA-2023837
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
FGFR2 mutant receptor activation R-HSA-1839126
FGFR2 ligand binding and activation R-HSA-190241
FGFR2 alternative splicing R-HSA-6803529
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-mediated signalling R-HSA-112399

Expression Atlas ENSG00000066468
LRG display in Ensembl gene LRG_994
NCBI gene (formerly Entrezgene) 2263
GeneCards 3689
HGNC Symbol HGNC:3689
MIM gene 176943
MIM morbid 614592
UniProtKB Gene Name S4R3B2
WikiGene 2263
Gene: FGFR4
Ensembl ID : ENSG00000160867
Description: fibroblast growth factor receptor 4
Gene Synonyms: CD334,JTK2
16 APIs:
122 Possible Orthologues:

betaKlotho-mediated ligand binding R-HSA-1307965
Signaling by FGFR4 in disease R-HSA-5655291
Insulin receptor signalling cascade R-HSA-74751
FGFR4 ligand binding and activation R-HSA-190322
Negative regulation of the PI3K/AKT network R-HSA-199418
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI-3K cascade:FGFR4 R-HSA-5654720
PIP3 activates AKT signaling R-HSA-1257604
IRS-mediated signalling R-HSA-112399
PI3K/AKT Signaling in Cancer R-HSA-2219528
FRS-mediated FGFR4 signaling R-HSA-5654712
MAPK family signaling cascades R-HSA-5683057
FGFR4 mutant receptor activation R-HSA-1839128
RAF/MAP kinase cascade R-HSA-5673001
IGF1R signaling cascade R-HSA-2428924
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by FGFR in disease R-HSA-1226099
betaKlotho-mediated ligand binding R-HSA-1307965
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of FGFR4 signaling R-HSA-5654733
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR4 R-HSA-5654743
Signaling by Insulin receptor R-HSA-74752
SHC-mediated cascade:FGFR4 R-HSA-5654719
Downstream signaling of activated FGFR4 R-HSA-5654716
Signal Transduction R-HSA-162582
Signaling by FGFR R-HSA-190236
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K Cascade R-HSA-109704
FGFR4 mutant receptor activation R-HSA-1839128
Signaling by FGFR in disease R-HSA-1226099
Disease R-HSA-1643685
Signaling by FGFR R-HSA-190236
PI3K/AKT Signaling in Cancer R-HSA-2219528
IGF1R signaling cascade R-HSA-2428924
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI3K Cascade R-HSA-109704
Signal Transduction R-HSA-162582
Downstream signaling of activated FGFR4 R-HSA-5654716
Negative regulation of FGFR4 signaling R-HSA-5654733
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
PIP3 activates AKT signaling R-HSA-1257604
IRS-mediated signalling R-HSA-112399
MAPK family signaling cascades R-HSA-5683057
FGFR4 ligand binding and activation R-HSA-190322
Insulin receptor signalling cascade R-HSA-74751
Intracellular signaling by second messengers R-HSA-9006925
IRS-related events triggered by IGF1R R-HSA-2428928
FRS-mediated FGFR4 signaling R-HSA-5654712
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 in disease R-HSA-5655291
SHC-mediated cascade:FGFR4 R-HSA-5654719
betaKlotho-mediated ligand binding R-HSA-1307965
RAF/MAP kinase cascade R-HSA-5673001
PI-3K cascade:FGFR4 R-HSA-5654720
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Insulin receptor R-HSA-74752
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR4 R-HSA-5654743
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
MAPK1/MAPK3 signaling R-HSA-5684996
PI-3K cascade:FGFR4 R-HSA-5654720
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downstream signaling of activated FGFR4 R-HSA-5654716
FRS-mediated FGFR4 signaling R-HSA-5654712
Signaling by FGFR4 R-HSA-5654743
IRS-mediated signalling R-HSA-112399
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR R-HSA-190236
MAPK family signaling cascades R-HSA-5683057
betaKlotho-mediated ligand binding R-HSA-1307965
PI3K Cascade R-HSA-109704
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR in disease R-HSA-1226099
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by Insulin receptor R-HSA-74752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
PIP3 activates AKT signaling R-HSA-1257604
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
FGFR4 ligand binding and activation R-HSA-190322
FGFR4 mutant receptor activation R-HSA-1839128
SHC-mediated cascade:FGFR4 R-HSA-5654719
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 in disease R-HSA-5655291
IGF1R signaling cascade R-HSA-2428924
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
FGFR4 mutant receptor activation R-HSA-1839128
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
IGF1R signaling cascade R-HSA-2428924
FGFR4 ligand binding and activation R-HSA-190322
Intracellular signaling by second messengers R-HSA-9006925
FRS-mediated FGFR4 signaling R-HSA-5654712
SHC-mediated cascade:FGFR4 R-HSA-5654719
Signaling by Insulin receptor R-HSA-74752
PI3K Cascade R-HSA-109704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS-mediated signalling R-HSA-112399
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by FGFR in disease R-HSA-1226099
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR4 signaling R-HSA-5654733
Negative regulation of the PI3K/AKT network R-HSA-199418
betaKlotho-mediated ligand binding R-HSA-1307965
IRS-related events triggered by IGF1R R-HSA-2428928
MAPK family signaling cascades R-HSA-5683057
PI-3K cascade:FGFR4 R-HSA-5654720
Signal Transduction R-HSA-162582
Downstream signaling of activated FGFR4 R-HSA-5654716
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by FGFR4 R-HSA-5654743
Signal Transduction R-HSA-162582
IRS-mediated signalling R-HSA-112399
Signaling by FGFR in disease R-HSA-1226099
MAPK family signaling cascades R-HSA-5683057
PI-3K cascade:FGFR4 R-HSA-5654720
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
RAF/MAP kinase cascade R-HSA-5673001
FRS-mediated FGFR4 signaling R-HSA-5654712
Signaling by FGFR4 in disease R-HSA-5655291
FGFR4 mutant receptor activation R-HSA-1839128
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by Insulin receptor R-HSA-74752
IGF1R signaling cascade R-HSA-2428924
FGFR4 ligand binding and activation R-HSA-190322
Negative regulation of the PI3K/AKT network R-HSA-199418
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC-mediated cascade:FGFR4 R-HSA-5654719
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Insulin receptor signalling cascade R-HSA-74751
PI3K/AKT Signaling in Cancer R-HSA-2219528
PI3K Cascade R-HSA-109704
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR4 R-HSA-5654743
Downstream signaling of activated FGFR4 R-HSA-5654716
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
IRS-mediated signalling R-HSA-112399
PIP3 activates AKT signaling R-HSA-1257604
SHC-mediated cascade:FGFR4 R-HSA-5654719
betaKlotho-mediated ligand binding R-HSA-1307965
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
Downstream signaling of activated FGFR4 R-HSA-5654716
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
FGFR4 mutant receptor activation R-HSA-1839128
RAF/MAP kinase cascade R-HSA-5673001
Insulin receptor signalling cascade R-HSA-74751
Negative regulation of the PI3K/AKT network R-HSA-199418
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by Insulin receptor R-HSA-74752
MAPK1/MAPK3 signaling R-HSA-5684996
IRS-related events triggered by IGF1R R-HSA-2428928
FGFR4 ligand binding and activation R-HSA-190322
FRS-mediated FGFR4 signaling R-HSA-5654712
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR4 signaling R-HSA-5654733
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR4 R-HSA-5654743
IGF1R signaling cascade R-HSA-2428924
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intracellular signaling by second messengers R-HSA-9006925
MAPK1/MAPK3 signaling R-HSA-5684996
PI-3K cascade:FGFR4 R-HSA-5654720
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
FGFR4 mutant receptor activation R-HSA-1839128
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR in disease R-HSA-1226099
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
IRS-mediated signalling R-HSA-112399
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signal Transduction R-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by FGFR4 R-HSA-5654743
RAF/MAP kinase cascade R-HSA-5673001
FGFR4 ligand binding and activation R-HSA-190322
PI3K Cascade R-HSA-109704
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
IGF1R signaling cascade R-HSA-2428924
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by Insulin receptor R-HSA-74752
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by FGFR R-HSA-190236
Signaling by FGFR4 in disease R-HSA-5655291
betaKlotho-mediated ligand binding R-HSA-1307965
FRS-mediated FGFR4 signaling R-HSA-5654712
Downstream signaling of activated FGFR4 R-HSA-5654716
SHC-mediated cascade:FGFR4 R-HSA-5654719
IRS-related events triggered by IGF1R R-HSA-2428928
IRS-mediated signalling R-HSA-112399
Negative regulation of FGFR4 signaling R-HSA-5654733
betaKlotho-mediated ligand binding R-HSA-1307965
MAPK1/MAPK3 signaling R-HSA-5684996
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
IRS-related events triggered by IGF1R R-HSA-2428928
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
Insulin receptor signalling cascade R-HSA-74751
FGFR4 mutant receptor activation R-HSA-1839128
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR4 R-HSA-5654743
PIP3 activates AKT signaling R-HSA-1257604
FGFR4 ligand binding and activation R-HSA-190322
PI3K Cascade R-HSA-109704
Signaling by FGFR in disease R-HSA-1226099
Downstream signaling of activated FGFR4 R-HSA-5654716
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FRS-mediated FGFR4 signaling R-HSA-5654712
Signaling by FGFR4 in disease R-HSA-5655291
Disease R-HSA-1643685
PI3K/AKT Signaling in Cancer R-HSA-2219528
SHC-mediated cascade:FGFR4 R-HSA-5654719
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by FGFR R-HSA-190236
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR R-HSA-190236
PI-3K cascade:FGFR4 R-HSA-5654720
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
FGFR4 ligand binding and activation R-HSA-190322
Signaling by FGFR in disease R-HSA-1226099
Insulin receptor signalling cascade R-HSA-74751
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of FGFR4 signaling R-HSA-5654733
SHC-mediated cascade:FGFR4 R-HSA-5654719
IRS-mediated signalling R-HSA-112399
Intracellular signaling by second messengers R-HSA-9006925
Signaling by FGFR4 R-HSA-5654743
FGFR4 mutant receptor activation R-HSA-1839128
IGF1R signaling cascade R-HSA-2428924
Negative regulation of the PI3K/AKT network R-HSA-199418
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
betaKlotho-mediated ligand binding R-HSA-1307965
MAPK1/MAPK3 signaling R-HSA-5684996
IRS-related events triggered by IGF1R R-HSA-2428928
Downstream signaling of activated FGFR4 R-HSA-5654716
PI3K Cascade R-HSA-109704
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FRS-mediated FGFR4 signaling R-HSA-5654712
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Insulin receptor R-HSA-74752
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR4 in disease R-HSA-5655291

Expression Atlas ENSG00000160867
NCBI gene (formerly Entrezgene) 2264
GeneCards 3691
HGNC Symbol HGNC:3691
MIM gene 134935
UniProtKB Gene Name P22455
WikiGene 2264
Gene: NPR3
Ensembl ID : ENSG00000113389
Description: natriuretic peptide receptor 3
Gene Synonyms: ANPRC,C5ORF23,FLJ14054,GUCY2B,NPRC
1 APIs:
210 Possible Orthologues:

Expression Atlas ENSG00000113389
NCBI gene (formerly Entrezgene) 4883
GeneCards 7945
HGNC Symbol HGNC:7945
MIM gene 108962
MIM morbid 619543
UniProtKB Gene Name Q60I31
WikiGene 4883