Gene: ELANE
Ensembl ID : ENSG00000197561
Description: elastase, neutrophil expressed
Gene Synonyms: ELA2,HLE,HNE,NE,PMN-E
2 APIs:
91 Possible Orthologues:

Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Pyroptosis R-HSA-5620971
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Programmed Cell Death R-HSA-5357801
Collagen degradation R-HSA-1442490
Antimicrobial peptides R-HSA-6803157
Regulation of Complement cascade R-HSA-977606
Extracellular matrix organization R-HSA-1474244
Complement cascade R-HSA-166658
Regulated Necrosis R-HSA-5218859
Neutrophil degranulation R-HSA-6798695
Antimicrobial peptides R-HSA-6803157
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Innate Immune System R-HSA-168249
Pyroptosis R-HSA-5620971
Regulated Necrosis R-HSA-5218859
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Complement cascade R-HSA-977606
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Degradation of the extracellular matrix R-HSA-1474228
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Collagen degradation R-HSA-1442490
Regulation of Complement cascade R-HSA-977606
Pyroptosis R-HSA-5620971
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Regulated Necrosis R-HSA-5218859
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Complement cascade R-HSA-166658
Programmed Cell Death R-HSA-5357801
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Complement cascade R-HSA-166658
Programmed Cell Death R-HSA-5357801
Antimicrobial peptides R-HSA-6803157
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Regulated Necrosis R-HSA-5218859
Immune System R-HSA-168256
Pyroptosis R-HSA-5620971
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Regulation of Complement cascade R-HSA-977606
Neutrophil degranulation R-HSA-6798695
Activation of Matrix Metalloproteinases R-HSA-1592389
Programmed Cell Death R-HSA-5357801
Extracellular matrix organization R-HSA-1474244
Regulation of Complement cascade R-HSA-977606
Immune System R-HSA-168256
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Pyroptosis R-HSA-5620971
Complement cascade R-HSA-166658
Pyroptosis R-HSA-5620971
Regulated Necrosis R-HSA-5218859
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Regulation of Complement cascade R-HSA-977606
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Antimicrobial peptides R-HSA-6803157
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Regulated Necrosis R-HSA-5218859
Collagen degradation R-HSA-1442490
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Activation of Matrix Metalloproteinases R-HSA-1592389
Regulation of Complement cascade R-HSA-977606
Programmed Cell Death R-HSA-5357801
Complement cascade R-HSA-166658
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Innate Immune System R-HSA-168249
Antimicrobial peptides R-HSA-6803157
Pyroptosis R-HSA-5620971
Immune System R-HSA-168256
Complement cascade R-HSA-166658
Degradation of the extracellular matrix R-HSA-1474228
Collagen degradation R-HSA-1442490
Regulation of Complement cascade R-HSA-977606
Activation of Matrix Metalloproteinases R-HSA-1592389
Neutrophil degranulation R-HSA-6798695
Antimicrobial peptides R-HSA-6803157
Innate Immune System R-HSA-168249
Regulated Necrosis R-HSA-5218859
Extracellular matrix organization R-HSA-1474244
Pyroptosis R-HSA-5620971
Programmed Cell Death R-HSA-5357801

Expression Atlas ENSG00000197561
LRG display in Ensembl gene LRG_57
NCBI gene (formerly Entrezgene) 1991
GeneCards 3309
HGNC Symbol HGNC:3309
MIM gene 130130
MIM morbid 202700
UniProtKB Gene Name P08246
WikiGene 1991
Gene: RAF1
Ensembl ID : ENSG00000132155
Description: Raf-1 proto-oncogene, serine/threonine kinase
Gene Synonyms: C-RAF,CRAF,RAF-1
7 APIs:
224 Possible Orthologues:

Signaling downstream of RAS mutants R-HSA-9649948
CD209 (DC-SIGN) signaling R-HSA-5621575
RAF activation R-HSA-5673000
Signaling by RAS mutants R-HSA-6802949
Signaling by RAF1 mutants R-HSA-9656223
Platelet activation, signaling and aggregation R-HSA-76002
Oncogenic MAPK signaling R-HSA-6802957
Transport of small molecules R-HSA-382551
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Innate Immune System R-HSA-168249
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Stimuli-sensing channels R-HSA-2672351
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Negative feedback regulation of MAPK pathway R-HSA-5674499
Adaptive Immune System R-HSA-1280218
GP1b-IX-V activation signalling R-HSA-430116
Immune System R-HSA-168256
Ion channel transport R-HSA-983712
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of MAPK pathway R-HSA-5675221
Signal Transduction R-HSA-162582
MAP2K and MAPK activation R-HSA-5674135
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Hemostasis R-HSA-109582
Rap1 signalling R-HSA-392517
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Hemostasis R-HSA-109582
Negative feedback regulation of MAPK pathway R-HSA-5674499
CD209 (DC-SIGN) signaling R-HSA-5621575
MAP2K and MAPK activation R-HSA-5674135
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Negative regulation of MAPK pathway R-HSA-5675221
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
Rap1 signalling R-HSA-392517
Signaling by RAF1 mutants R-HSA-9656223
Signaling by RAS mutants R-HSA-6802949
MAPK family signaling cascades R-HSA-5683057
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
GP1b-IX-V activation signalling R-HSA-430116
Innate Immune System R-HSA-168249
Ion channel transport R-HSA-983712
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
Stimuli-sensing channels R-HSA-2672351
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Signaling by MRAS-complex mutants R-HSA-9660537
Transport of small molecules R-HSA-382551
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF activation R-HSA-5673000
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling downstream of RAS mutants R-HSA-9649948
GP1b-IX-V activation signalling R-HSA-430116
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by RAF1 mutants R-HSA-9656223
Immune System R-HSA-168256
Transport of small molecules R-HSA-382551
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Oncogenic MAPK signaling R-HSA-6802957
RAF activation R-HSA-5673000
MAPK family signaling cascades R-HSA-5683057
C-type lectin receptors (CLRs) R-HSA-5621481
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Ion channel transport R-HSA-983712
Platelet activation, signaling and aggregation R-HSA-76002
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by MRAS-complex mutants R-HSA-9660537
CD209 (DC-SIGN) signaling R-HSA-5621575
Signaling downstream of RAS mutants R-HSA-9649948
Stimuli-sensing channels R-HSA-2672351
Rap1 signalling R-HSA-392517
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
MAP2K and MAPK activation R-HSA-5674135
Signaling by RAS mutants R-HSA-6802949
Hemostasis R-HSA-109582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF activation R-HSA-5673000
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Negative regulation of MAPK pathway R-HSA-5675221
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
MAPK family signaling cascades R-HSA-5683057
Signaling by RAS mutants R-HSA-6802949
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
GP1b-IX-V activation signalling R-HSA-430116
Oncogenic MAPK signaling R-HSA-6802957
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Platelet activation, signaling and aggregation R-HSA-76002
Adaptive Immune System R-HSA-1280218
Hemostasis R-HSA-109582
Rap1 signalling R-HSA-392517
MAP2K and MAPK activation R-HSA-5674135
Transport of small molecules R-HSA-382551
Signaling downstream of RAS mutants R-HSA-9649948
Stimuli-sensing channels R-HSA-2672351
C-type lectin receptors (CLRs) R-HSA-5621481
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
MAPK1/MAPK3 signaling R-HSA-5684996
CD209 (DC-SIGN) signaling R-HSA-5621575
RAF/MAP kinase cascade R-HSA-5673001
Signaling by MRAS-complex mutants R-HSA-9660537
Ion channel transport R-HSA-983712
Signaling by RAF1 mutants R-HSA-9656223
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
RAF activation R-HSA-5673000
MAP2K and MAPK activation R-HSA-5674135
Rap1 signalling R-HSA-392517
CD209 (DC-SIGN) signaling R-HSA-5621575
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Hemostasis R-HSA-109582
Ion channel transport R-HSA-983712
Negative regulation of MAPK pathway R-HSA-5675221
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transport of small molecules R-HSA-382551
Stimuli-sensing channels R-HSA-2672351
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Platelet activation, signaling and aggregation R-HSA-76002
RAF/MAP kinase cascade R-HSA-5673001
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by MRAS-complex mutants R-HSA-9660537
Adaptive Immune System R-HSA-1280218
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
GP1b-IX-V activation signalling R-HSA-430116
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by RAF1 mutants R-HSA-9656223
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by MRAS-complex mutants R-HSA-9660537
Oncogenic MAPK signaling R-HSA-6802957
RAF activation R-HSA-5673000
MAP2K and MAPK activation R-HSA-5674135
MAPK1/MAPK3 signaling R-HSA-5684996
Ion channel transport R-HSA-983712
GP1b-IX-V activation signalling R-HSA-430116
Negative regulation of MAPK pathway R-HSA-5675221
Platelet activation, signaling and aggregation R-HSA-76002
Stimuli-sensing channels R-HSA-2672351
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Rap1 signalling R-HSA-392517
Transport of small molecules R-HSA-382551
Signaling by RAS mutants R-HSA-6802949
Signaling downstream of RAS mutants R-HSA-9649948
MAPK family signaling cascades R-HSA-5683057
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Adaptive Immune System R-HSA-1280218
CD209 (DC-SIGN) signaling R-HSA-5621575
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling by RAF1 mutants R-HSA-9656223
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Hemostasis R-HSA-109582
Innate Immune System R-HSA-168249
Signaling by MRAS-complex mutants R-HSA-9660537
Signal Transduction R-HSA-162582
Negative feedback regulation of MAPK pathway R-HSA-5674499
Negative regulation of MAPK pathway R-HSA-5675221
GP1b-IX-V activation signalling R-HSA-430116
Immune System R-HSA-168256
RAF activation R-HSA-5673000
Adaptive Immune System R-HSA-1280218
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Stimuli-sensing channels R-HSA-2672351
CD209 (DC-SIGN) signaling R-HSA-5621575
Oncogenic MAPK signaling R-HSA-6802957
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Innate Immune System R-HSA-168249
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Ion channel transport R-HSA-983712
MAP2K and MAPK activation R-HSA-5674135
Hemostasis R-HSA-109582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by RAS mutants R-HSA-6802949
C-type lectin receptors (CLRs) R-HSA-5621481
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by RAF1 mutants R-HSA-9656223
Rap1 signalling R-HSA-392517
Signaling downstream of RAS mutants R-HSA-9649948
Transport of small molecules R-HSA-382551
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by RAF1 mutants R-HSA-9656223
Immune System R-HSA-168256
Signaling downstream of RAS mutants R-HSA-9649948
Negative feedback regulation of MAPK pathway R-HSA-5674499
Platelet activation, signaling and aggregation R-HSA-76002
MAPK1/MAPK3 signaling R-HSA-5684996
Oncogenic MAPK signaling R-HSA-6802957
Signaling by MRAS-complex mutants R-HSA-9660537
RAF/MAP kinase cascade R-HSA-5673001
Innate Immune System R-HSA-168249
Signaling by BRAF and RAF1 fusions R-HSA-6802952
GP1b-IX-V activation signalling R-HSA-430116
Signal Transduction R-HSA-162582
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Hemostasis R-HSA-109582
MAPK family signaling cascades R-HSA-5683057
Ion channel transport R-HSA-983712
Stimuli-sensing channels R-HSA-2672351
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Rap1 signalling R-HSA-392517
Negative regulation of MAPK pathway R-HSA-5675221
RAF activation R-HSA-5673000
CD209 (DC-SIGN) signaling R-HSA-5621575
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
MAP2K and MAPK activation R-HSA-5674135
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Oncogenic MAPK signaling R-HSA-6802957
Innate Immune System R-HSA-168249
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
Transport of small molecules R-HSA-382551
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
C-type lectin receptors (CLRs) R-HSA-5621481
Rap1 signalling R-HSA-392517
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Signaling by MRAS-complex mutants R-HSA-9660537
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Ion channel transport R-HSA-983712
Signaling by RAS mutants R-HSA-6802949
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
GP1b-IX-V activation signalling R-HSA-430116
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF/MAP kinase cascade R-HSA-5673001
Stimuli-sensing channels R-HSA-2672351
Signaling downstream of RAS mutants R-HSA-9649948
CD209 (DC-SIGN) signaling R-HSA-5621575
RAF activation R-HSA-5673000
Negative feedback regulation of MAPK pathway R-HSA-5674499
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
MAPK1/MAPK3 signaling R-HSA-5684996
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
MAP2K and MAPK activation R-HSA-5674135
Signaling by BRAF and RAF1 fusions R-HSA-6802952
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Rap1 signalling R-HSA-392517
CD209 (DC-SIGN) signaling R-HSA-5621575
Signaling by RAS mutants R-HSA-6802949
MAPK1/MAPK3 signaling R-HSA-5684996
Platelet activation, signaling and aggregation R-HSA-76002
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Stimuli-sensing channels R-HSA-2672351
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Ion channel transport R-HSA-983712
Signaling downstream of RAS mutants R-HSA-9649948
MAPK family signaling cascades R-HSA-5683057
Negative regulation of MAPK pathway R-HSA-5675221
Transport of small molecules R-HSA-382551
Immune System R-HSA-168256
GP1b-IX-V activation signalling R-HSA-430116
RAF/MAP kinase cascade R-HSA-5673001
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAP2K and MAPK activation R-HSA-5674135
Signaling by MRAS-complex mutants R-HSA-9660537
Hemostasis R-HSA-109582
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative feedback regulation of MAPK pathway R-HSA-5674499
RAF activation R-HSA-5673000

Expression Atlas ENSG00000132155
LRG display in Ensembl gene LRG_413
NCBI gene (formerly Entrezgene) 5894
GeneCards 9829
HGNC Symbol HGNC:9829
MIM gene 164760
MIM morbid 615916
UniProtKB Gene Name P04049
WikiGene 5894
Gene: NPM1
Ensembl ID : ENSG00000181163
Description: nucleophosmin 1
Gene Synonyms: B23,NPM
2 APIs:
158 Possible Orthologues:

Chromosome Maintenance R-HSA-73886
SARS-CoV-1 Infection R-HSA-9678108
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Nucleosome assembly R-HSA-774815
Interactions of Rev with host cellular proteins R-HSA-177243
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
ALK mutants bind TKIs R-HSA-9700645
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle R-HSA-1640170
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SARS-CoV-1-host interactions R-HSA-9692914
HIV Infection R-HSA-162906
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Host Interactions of HIV factors R-HSA-162909
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
SUMOylation of transcription cofactors R-HSA-3899300
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
Gene expression (Transcription) R-HSA-74160
SARS-CoV Infections R-HSA-9679506
Nuclear import of Rev protein R-HSA-180746
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
SARS-CoV-1-host interactions R-HSA-9692914
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cell Cycle R-HSA-1640170
Interactions of Rev with host cellular proteins R-HSA-177243
HIV Infection R-HSA-162906
SARS-CoV-1 Infection R-HSA-9678108
Chromosome Maintenance R-HSA-73886
Nucleosome assembly R-HSA-774815
Nuclear import of Rev protein R-HSA-180746
SUMOylation of transcription cofactors R-HSA-3899300
Disease R-HSA-1643685
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Generic Transcription Pathway R-HSA-212436
Signaling by ALK in cancer R-HSA-9700206
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
ALK mutants bind TKIs R-HSA-9700645
SARS-CoV Infections R-HSA-9679506
Gene expression (Transcription) R-HSA-74160
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
SUMOylation of transcription cofactors R-HSA-3899300
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Generic Transcription Pathway R-HSA-212436
SARS-CoV Infections R-HSA-9679506
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
Host Interactions of HIV factors R-HSA-162909
Post-translational protein modification R-HSA-597592
Chromosome Maintenance R-HSA-73886
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
SUMOylation R-HSA-2990846
SARS-CoV-1 Infection R-HSA-9678108
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
Nucleosome assembly R-HSA-774815
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Signaling by ALK fusions and activated point mutants R-HSA-9725370
SARS-CoV-1-host interactions R-HSA-9692914
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Cell Cycle R-HSA-1640170
ALK mutants bind TKIs R-HSA-9700645
Nuclear import of Rev protein R-HSA-180746
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Transcriptional Regulation by TP53 R-HSA-3700989
Interactions of Rev with host cellular proteins R-HSA-177243
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interactions of Rev with host cellular proteins R-HSA-177243
Host Interactions of HIV factors R-HSA-162909
SARS-CoV-1 Infection R-HSA-9678108
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
Signaling by ALK in cancer R-HSA-9700206
Metabolism of proteins R-HSA-392499
Nuclear import of Rev protein R-HSA-180746
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Nucleosome assembly R-HSA-774815
Generic Transcription Pathway R-HSA-212436
ALK mutants bind TKIs R-HSA-9700645
Post-translational protein modification R-HSA-597592
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Disease R-HSA-1643685
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Infectious disease R-HSA-5663205
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
SUMOylation R-HSA-2990846
SUMOylation of transcription cofactors R-HSA-3899300
Chromosome Maintenance R-HSA-73886
Gene expression (Transcription) R-HSA-74160
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV Infections R-HSA-9679506
Transcriptional Regulation by TP53 R-HSA-3700989
HIV Infection R-HSA-162906
SARS-CoV-1-host interactions R-HSA-9692914
Generic Transcription Pathway R-HSA-212436
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interactions of Rev with host cellular proteins R-HSA-177243
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Cell Cycle R-HSA-1640170
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
SUMOylation of transcription cofactors R-HSA-3899300
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Chromosome Maintenance R-HSA-73886
Nuclear import of Rev protein R-HSA-180746
SARS-CoV-1 Infection R-HSA-9678108
HIV Infection R-HSA-162906
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Transcriptional Regulation by TP53 R-HSA-3700989
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
SARS-CoV Infections R-HSA-9679506
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Nucleosome assembly R-HSA-774815

Expression Atlas ENSG00000181163
LRG display in Ensembl gene LRG_458
NCBI gene (formerly Entrezgene) 4869
GeneCards 7910
HGNC Symbol HGNC:7910
MIM gene 164040
MIM morbid 601626
UniProtKB Gene Name P06748
WikiGene 4869
Gene: CYP17A1
Ensembl ID : ENSG00000148795
Description: cytochrome P450 family 17 subfamily A member 1
Gene Synonyms: CPT7,CYP17,P450C17,S17AH
4 APIs:
211 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Disease R-HSA-1643685
Androgen biosynthesis R-HSA-193048
Defective CYP17A1 causes AH5 R-HSA-5579028
Metabolism of lipids R-HSA-556833
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Glucocorticoid biosynthesis R-HSA-194002
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Androgen biosynthesis R-HSA-193048
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Defective CYP17A1 causes AH5 R-HSA-5579028
Defective CYP17A1 causes AH5 R-HSA-5579028
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Disease R-HSA-1643685
Metabolism of steroid hormones R-HSA-196071
Androgen biosynthesis R-HSA-193048
Diseases of metabolism R-HSA-5668914
Defective CYP17A1 causes AH5 R-HSA-5579028
Diseases of metabolism R-HSA-5668914
Androgen biosynthesis R-HSA-193048
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Glucocorticoid biosynthesis R-HSA-194002
Disease R-HSA-1643685
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroids R-HSA-8957322
Glucocorticoid biosynthesis R-HSA-194002
Disease R-HSA-1643685
Defective CYP17A1 causes AH5 R-HSA-5579028
Diseases of metabolism R-HSA-5668914
Metabolism of lipids R-HSA-556833
Androgen biosynthesis R-HSA-193048
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Metabolism of steroid hormones R-HSA-196071
Androgen biosynthesis R-HSA-193048
Metabolism R-HSA-1430728
Defective CYP17A1 causes AH5 R-HSA-5579028
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of steroid hormones R-HSA-196071
Defective CYP17A1 causes AH5 R-HSA-5579028
Metabolism R-HSA-1430728
Androgen biosynthesis R-HSA-193048
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Defective CYP17A1 causes AH5 R-HSA-5579028
Androgen biosynthesis R-HSA-193048
Metabolism R-HSA-1430728
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroids R-HSA-8957322
Disease R-HSA-1643685
Glucocorticoid biosynthesis R-HSA-194002
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Metabolism of steroid hormones R-HSA-196071
Diseases of metabolism R-HSA-5668914
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroid hormones R-HSA-196071
Glucocorticoid biosynthesis R-HSA-194002
Disease R-HSA-1643685
Androgen biosynthesis R-HSA-193048
Defective CYP17A1 causes AH5 R-HSA-5579028
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Metabolism of steroids R-HSA-8957322
Glucocorticoid biosynthesis R-HSA-194002
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Defective CYP17A1 causes AH5 R-HSA-5579028
Androgen biosynthesis R-HSA-193048

Expression Atlas ENSG00000148795
NCBI gene (formerly Entrezgene) 1586
GeneCards 2593
HGNC Symbol HGNC:2593
MIM gene 609300
MIM morbid 202110
UniProtKB Gene Name Q1HB44
WikiGene 1586
Gene: TIE1
Ensembl ID : ENSG00000066056
Description: tyrosine kinase with immunoglobulin like and EGF like domains 1
Gene Synonyms: JTK14,TIE
1 APIs:
205 Possible Orthologues:

Expression Atlas ENSG00000066056
NCBI gene (formerly Entrezgene) 7075
GeneCards 11809
HGNC Symbol HGNC:11809
MIM gene 600222
MIM morbid 619401
UniProtKB Gene Name P35590
WikiGene 7075
Gene: PSMD11
Ensembl ID : ENSG00000108671
Description: proteasome 26S subunit, non-ATPase 11
Gene Synonyms: MGC3844,P44.5,RPN6,S9
5 APIs:
283 Possible Orthologues:

DNA Replication R-HSA-69306
Metabolism R-HSA-1430728
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
MAPK family signaling cascades R-HSA-5683057
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Cell Cycle, Mitotic R-HSA-69278
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by WNT R-HSA-195721
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Hedgehog R-HSA-5358351
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
S Phase R-HSA-69242
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Immune System R-HSA-168256
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of RNA R-HSA-8953854
Stabilization of p53 R-HSA-69541
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular response to hypoxia R-HSA-1234174
Mitotic G1 phase and G1/S transition R-HSA-453279
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism R-HSA-1430728
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by NOTCH4 R-HSA-9013694
Neutrophil degranulation R-HSA-6798695
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disease R-HSA-1643685
G1/S DNA Damage Checkpoints R-HSA-69615
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Metaphase and Anaphase R-HSA-2555396
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Transition R-HSA-69275
Degradation of AXIN R-HSA-4641257
Assembly of the pre-replicative complex R-HSA-68867
Hh mutants are degraded by ERAD R-HSA-5362768
Vif-mediated degradation of APOBEC3G R-HSA-180585
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
Signal Transduction R-HSA-162582
Mitotic Anaphase R-HSA-68882
Ub-specific processing proteases R-HSA-5689880
TCR signaling R-HSA-202403
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI2 by the proteasome R-HSA-5610783
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX2 R-HSA-8878166
ABC transporter disorders R-HSA-5619084
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
Signaling by ROBO receptors R-HSA-376176
Regulation of Apoptosis R-HSA-169911
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
Hh mutants abrogate ligand secretion R-HSA-5387390
Synthesis of DNA R-HSA-69239
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of amino acids and derivatives R-HSA-71291
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Host Interactions of HIV factors R-HSA-162909
Nervous system development R-HSA-9675108
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
FCERI mediated NF-kB activation R-HSA-2871837
Programmed Cell Death R-HSA-5357801
DNA Replication R-HSA-69306
C-type lectin receptors (CLRs) R-HSA-5621481
Host Interactions of HIV factors R-HSA-162909
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCR signaling R-HSA-202403
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Mitotic Metaphase and Anaphase R-HSA-2555396
M Phase R-HSA-68886
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of DVL R-HSA-4641258
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI1 by the proteasome R-HSA-5610780
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mitotic cell cycle R-HSA-453276
Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Activation of NF-kappaB in B cells R-HSA-1169091
Hedgehog 'off' state R-HSA-5610787
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by NOTCH R-HSA-157118
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S DNA Damage Checkpoints R-HSA-69615
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Negative regulation of NOTCH4 signaling R-HSA-9604323
Neutrophil degranulation R-HSA-6798695
Gene expression (Transcription) R-HSA-74160
ABC transporter disorders R-HSA-5619084
Transport of small molecules R-HSA-382551
ER-Phagosome pathway R-HSA-1236974
Developmental Biology R-HSA-1266738
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Nervous system development R-HSA-9675108
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Disorders of transmembrane transporters R-HSA-5619115
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle Checkpoints R-HSA-69620
p53-Independent DNA Damage Response R-HSA-69610
TCF dependent signaling in response to WNT R-HSA-201681
Cellular responses to stimuli R-HSA-8953897
Orc1 removal from chromatin R-HSA-68949
Metabolism of amino acids and derivatives R-HSA-71291
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing-Cross presentation R-HSA-1236975
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Adaptive Immune System R-HSA-1280218
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
Intracellular signaling by second messengers R-HSA-9006925
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by ROBO receptors R-HSA-376176
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH4 R-HSA-9013694
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mitotic cell cycle R-HSA-453276
Orc1 removal from chromatin R-HSA-68949
Vif-mediated degradation of APOBEC3G R-HSA-180585
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
Degradation of DVL R-HSA-4641258
Signaling by Interleukins R-HSA-449147
Developmental Biology R-HSA-1266738
C-type lectin receptors (CLRs) R-HSA-5621481
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of AXIN R-HSA-4641257
Neddylation R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Apoptosis R-HSA-109581
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by the B Cell Receptor (BCR) R-HSA-983705
KEAP1-NFE2L2 pathway R-HSA-9755511
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of GLI2 by the proteasome R-HSA-5610783
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
Infectious disease R-HSA-5663205
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Regulation of Apoptosis R-HSA-169911
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Neutrophil degranulation R-HSA-6798695
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by ROBO receptors R-HSA-376176
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RNA Polymerase II Transcription R-HSA-73857
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX1 R-HSA-8878171
Intracellular signaling by second messengers R-HSA-9006925
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Independent DNA Damage Response R-HSA-69610
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
M Phase R-HSA-68886
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Vpu mediated degradation of CD4 R-HSA-180534
MAPK6/MAPK4 signaling R-HSA-5687128
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'off' state R-HSA-5610787
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Interleukin-1 signaling R-HSA-9020702
Separation of Sister Chromatids R-HSA-2467813
MAPK1/MAPK3 signaling R-HSA-5684996
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI1 by the proteasome R-HSA-5610780
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Regulation of RUNX2 expression and activity R-HSA-8939902
Programmed Cell Death R-HSA-5357801
Cell Cycle R-HSA-1640170
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Disease R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Signaling by WNT R-HSA-195721
DNA Replication R-HSA-69306
ABC transporter disorders R-HSA-5619084
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
Synthesis of DNA R-HSA-69239
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Checkpoints R-HSA-69481
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
Adaptive Immune System R-HSA-1280218
MAPK6/MAPK4 signaling R-HSA-5687128
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of AXIN R-HSA-4641257
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
DNA Replication R-HSA-69306
Cellular responses to stimuli R-HSA-8953897
Mitotic Metaphase and Anaphase R-HSA-2555396
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of polyamines R-HSA-351202
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
ABC-family proteins mediated transport R-HSA-382556
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Developmental Biology R-HSA-1266738
Deubiquitination R-HSA-5688426
Antigen processing-Cross presentation R-HSA-1236975
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by NOTCH R-HSA-157118
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Class I MHC mediated antigen processing & presentation R-HSA-983169
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RUNX3 expression and activity R-HSA-8941858
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
Transcriptional regulation by RUNX3 R-HSA-8878159
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH4 R-HSA-9013694
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Cellular response to chemical stress R-HSA-9711123
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Axon guidance R-HSA-422475
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of Apoptosis R-HSA-169911
Immune System R-HSA-168256
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC transporter disorders R-HSA-5619084
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
p53-Independent DNA Damage Response R-HSA-69610
Signaling by Hedgehog R-HSA-5358351
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Orc1 removal from chromatin R-HSA-68949
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
PCP/CE pathway R-HSA-4086400
Neutrophil degranulation R-HSA-6798695
Hedgehog 'on' state R-HSA-5632684
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disease R-HSA-1643685
PTEN Regulation R-HSA-6807070
Nervous system development R-HSA-9675108
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of beta-catenin by the destruction complex R-HSA-195253
G1/S Transition R-HSA-69206
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of amino acids and derivatives R-HSA-71291
UCH proteinases R-HSA-5689603
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
Cell Cycle Checkpoints R-HSA-69620
Post-translational protein modification R-HSA-597592
M Phase R-HSA-68886
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Neddylation R-HSA-8951664
Switching of origins to a post-replicative state R-HSA-69052
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
ABC-family proteins mediated transport R-HSA-382556
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hh mutants are degraded by ERAD R-HSA-5362768
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Class I MHC mediated antigen processing & presentation R-HSA-983169
Degradation of GLI2 by the proteasome R-HSA-5610783
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Cell Cycle R-HSA-1640170
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCF dependent signaling in response to WNT R-HSA-201681
Hedgehog 'off' state R-HSA-5610787
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Programmed Cell Death R-HSA-5357801
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular response to chemical stress R-HSA-9711123
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Beta-catenin independent WNT signaling R-HSA-3858494
PCP/CE pathway R-HSA-4086400
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
UCH proteinases R-HSA-5689603
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Adaptive Immune System R-HSA-1280218
PTEN Regulation R-HSA-6807070
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX3 R-HSA-8878159
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mitotic cell cycle R-HSA-453276
p53-Independent DNA Damage Response R-HSA-69610
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TCR signaling R-HSA-202403
Metabolism of amino acids and derivatives R-HSA-71291
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Orc1 removal from chromatin R-HSA-68949
Cytokine Signaling in Immune system R-HSA-1280215
MAPK family signaling cascades R-HSA-5683057
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Nuclear events mediated by NFE2L2 R-HSA-9759194
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Developmental Biology R-HSA-1266738
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic Anaphase R-HSA-68882
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants abrogate ligand secretion R-HSA-5387390
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Signaling by WNT R-HSA-195721
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RAS by GAPs R-HSA-5658442
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
G2/M Checkpoints R-HSA-69481
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
Signaling by NOTCH4 R-HSA-9013694
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Synthesis of DNA R-HSA-69239
Antigen processing-Cross presentation R-HSA-1236975
Degradation of DVL R-HSA-4641258
Cellular responses to stress R-HSA-2262752
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular responses to stimuli R-HSA-8953897
G2/M Transition R-HSA-69275
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Asymmetric localization of PCP proteins R-HSA-4608870
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of polyamines R-HSA-351202
Transport of small molecules R-HSA-382551
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S Transition R-HSA-69206
Gene expression (Transcription) R-HSA-74160
Interleukin-1 family signaling R-HSA-446652
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Axon guidance R-HSA-422475
Apoptosis R-HSA-109581
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX3 expression and activity R-HSA-8941858
Programmed Cell Death R-HSA-5357801
Orc1 removal from chromatin R-HSA-68949
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Hedgehog 'on' state R-HSA-5632684
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of RUNX2 expression and activity R-HSA-8939902
Generic Transcription Pathway R-HSA-212436
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Hedgehog R-HSA-5358351
p53-Independent DNA Damage Response R-HSA-69610
Gene expression (Transcription) R-HSA-74160
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular responses to stress R-HSA-2262752
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PCP/CE pathway R-HSA-4086400
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Disorders of transmembrane transporters R-HSA-5619115
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Adaptive Immune System R-HSA-1280218
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Activation of NF-kappaB in B cells R-HSA-1169091
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Post-translational protein modification R-HSA-597592
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication R-HSA-69306
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
C-type lectin receptors (CLRs) R-HSA-5621481
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle, Mitotic R-HSA-69278
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'off' state R-HSA-5610787
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Ub-specific processing proteases R-HSA-5689880
Neddylation R-HSA-8951664
Apoptosis R-HSA-109581
Metabolism of proteins R-HSA-392499
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
ABC-family proteins mediated transport R-HSA-382556
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
Regulation of mitotic cell cycle R-HSA-453276
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Developmental Biology R-HSA-1266738
G2/M Checkpoints R-HSA-69481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
M Phase R-HSA-68886
Intracellular signaling by second messengers R-HSA-9006925
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Regulation of Apoptosis R-HSA-169911
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of RNA R-HSA-8953854
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G2-G2/M phases R-HSA-453274
Mitotic Anaphase R-HSA-68882
Regulation of PTEN stability and activity R-HSA-8948751
Switching of origins to a post-replicative state R-HSA-69052
Immune System R-HSA-168256
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX3 R-HSA-8878159
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Nervous system development R-HSA-9675108
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of GLI2 by the proteasome R-HSA-5610783
Nervous system development R-HSA-9675108
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
MAPK family signaling cascades R-HSA-5683057
Degradation of DVL R-HSA-4641258
Adaptive Immune System R-HSA-1280218
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Axon guidance R-HSA-422475
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Innate Immune System R-HSA-168249
Regulation of Apoptosis R-HSA-169911
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of PTEN stability and activity R-HSA-8948751
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Separation of Sister Chromatids R-HSA-2467813
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'off' state R-HSA-5610787
Stabilization of p53 R-HSA-69541
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
PCP/CE pathway R-HSA-4086400
MAPK6/MAPK4 signaling R-HSA-5687128
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Neddylation R-HSA-8951664
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
TCF dependent signaling in response to WNT R-HSA-201681
HIV Infection R-HSA-162906
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Degradation of GLI1 by the proteasome R-HSA-5610780
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RAS by GAPs R-HSA-5658442
ABC-family proteins mediated transport R-HSA-382556
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
Mitotic Metaphase and Anaphase R-HSA-2555396
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
S Phase R-HSA-69242
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Cellular response to chemical stress R-HSA-9711123
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Mitotic G1 phase and G1/S transition R-HSA-453279
Antigen processing-Cross presentation R-HSA-1236975
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of DVL R-HSA-4641258
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle R-HSA-1640170
C-type lectin receptors (CLRs) R-HSA-5621481
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of PTEN stability and activity R-HSA-8948751
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ub-specific processing proteases R-HSA-5689880
G2/M Checkpoints R-HSA-69481
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Hedgehog R-HSA-5358351
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular response to hypoxia R-HSA-1234174
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Interleukins R-HSA-449147
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
G2/M Transition R-HSA-69275
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by NOTCH R-HSA-157118
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC-family proteins mediated transport R-HSA-382556
Immune System R-HSA-168256
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
NIK-->noncanonical NF-kB signaling R-HSA-5676590
DNA Replication Pre-Initiation R-HSA-69002
Programmed Cell Death R-HSA-5357801
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Deubiquitination R-HSA-5688426
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
Neddylation R-HSA-8951664
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PTEN Regulation R-HSA-6807070
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Cyclin E associated events during G1/S transition R-HSA-69202
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of Apoptosis R-HSA-169911
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Metabolism of RNA R-HSA-8953854
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Mitotic Anaphase R-HSA-68882
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of polyamines R-HSA-351202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Separation of Sister Chromatids R-HSA-2467813
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Independent DNA Damage Response R-HSA-69610
PCP/CE pathway R-HSA-4086400
Nervous system development R-HSA-9675108
TCF dependent signaling in response to WNT R-HSA-201681
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Assembly of the pre-replicative complex R-HSA-68867
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
ABC transporter disorders R-HSA-5619084
Hedgehog 'off' state R-HSA-5610787
PIP3 activates AKT signaling R-HSA-1257604
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Cellular responses to stimuli R-HSA-8953897
Defective CFTR causes cystic fibrosis R-HSA-5678895
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
Post-translational protein modification R-HSA-597592
Neutrophil degranulation R-HSA-6798695
Orc1 removal from chromatin R-HSA-68949
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants abrogate ligand secretion R-HSA-5387390
Signal Transduction R-HSA-162582
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI1 by the proteasome R-HSA-5610780
MAPK family signaling cascades R-HSA-5683057
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Neddylation R-HSA-8951664
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream TCR signaling R-HSA-202424
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic Anaphase R-HSA-68882
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle, Mitotic R-HSA-69278
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by NOTCH R-HSA-157118
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
ER-Phagosome pathway R-HSA-1236974
Neutrophil degranulation R-HSA-6798695
KEAP1-NFE2L2 pathway R-HSA-9755511
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
G2/M Checkpoints R-HSA-69481
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Programmed Cell Death R-HSA-5357801
Stabilization of p53 R-HSA-69541
PCP/CE pathway R-HSA-4086400
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
Adaptive Immune System R-HSA-1280218
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Interleukin-1 signaling R-HSA-9020702
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
UCH proteinases R-HSA-5689603
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Host Interactions of HIV factors R-HSA-162909
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Vif-mediated degradation of APOBEC3G R-HSA-180585
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
RNA Polymerase II Transcription R-HSA-73857
Cellular response to hypoxia R-HSA-1234174
Assembly of the pre-replicative complex R-HSA-68867
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
Cellular response to chemical stress R-HSA-9711123
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Signaling by Interleukins R-HSA-449147
Class I MHC mediated antigen processing & presentation R-HSA-983169
MAPK6/MAPK4 signaling R-HSA-5687128
Disease R-HSA-1643685
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by Hedgehog R-HSA-5358351
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
Deubiquitination R-HSA-5688426
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Disorders of transmembrane transporters R-HSA-5619115
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Apoptosis R-HSA-109581
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX2 expression and activity R-HSA-8939902
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G1/S Transition R-HSA-69206
Regulation of mitotic cell cycle R-HSA-453276
Regulation of RUNX3 expression and activity R-HSA-8941858
HIV Infection R-HSA-162906
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 family signaling R-HSA-446652
Transcriptional regulation by RUNX1 R-HSA-8878171
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
Stabilization of p53 R-HSA-69541
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
Assembly of the pre-replicative complex R-HSA-68867
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic Anaphase R-HSA-68882
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cell Cycle, Mitotic R-HSA-69278
Cyclin E associated events during G1/S transition R-HSA-69202
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Metabolism R-HSA-1430728
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by Hedgehog R-HSA-5358351
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cell Cycle Checkpoints R-HSA-69620
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Disease R-HSA-1643685
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
UCH proteinases R-HSA-5689603
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX2 R-HSA-8878166
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Independent DNA Damage Response R-HSA-69610
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Degradation of GLI2 by the proteasome R-HSA-5610783
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G2/M Transition R-HSA-69275
Generic Transcription Pathway R-HSA-212436
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream TCR signaling R-HSA-202424
MAPK family signaling cascades R-HSA-5683057
Signaling by ROBO receptors R-HSA-376176
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
S Phase R-HSA-69242
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
RAF/MAP kinase cascade R-HSA-5673001
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Gene expression (Transcription) R-HSA-74160
Degradation of AXIN R-HSA-4641257
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by NOTCH R-HSA-157118
ABC-family proteins mediated transport R-HSA-382556
Cellular responses to stress R-HSA-2262752
ER-Phagosome pathway R-HSA-1236974
TCR signaling R-HSA-202403
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of beta-catenin by the destruction complex R-HSA-195253
KEAP1-NFE2L2 pathway R-HSA-9755511
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Interleukin-1 signaling R-HSA-9020702
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of PTEN stability and activity R-HSA-8948751
ABC transporter disorders R-HSA-5619084
Intracellular signaling by second messengers R-HSA-9006925
PTEN Regulation R-HSA-6807070
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication Pre-Initiation R-HSA-69002
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Host Interactions of HIV factors R-HSA-162909
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Activation of NF-kappaB in B cells R-HSA-1169091
Metabolism of polyamines R-HSA-351202
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1 DNA Damage Response R-HSA-69563
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Cytokine Signaling in Immune system R-HSA-1280215
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Cellular responses to stress R-HSA-2262752
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
TCR signaling R-HSA-202403
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Hedgehog 'on' state R-HSA-5632684
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH R-HSA-157118
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing-Cross presentation R-HSA-1236975
Neutrophil degranulation R-HSA-6798695
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Transition R-HSA-69275
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Degradation of GLI1 by the proteasome R-HSA-5610780
ABC-family proteins mediated transport R-HSA-382556
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
Developmental Biology R-HSA-1266738
Metabolism of RNA R-HSA-8953854
UCH proteinases R-HSA-5689603
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
RNA Polymerase II Transcription R-HSA-73857
Signaling by NOTCH4 R-HSA-9013694
Innate Immune System R-HSA-168249
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Transport of small molecules R-HSA-382551
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cell Cycle Checkpoints R-HSA-69620
Hh mutants are degraded by ERAD R-HSA-5362768
M Phase R-HSA-68886
Interleukin-1 family signaling R-HSA-446652
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX2 R-HSA-8878166
MAPK family signaling cascades R-HSA-5683057
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of DVL R-HSA-4641258
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of polyamines R-HSA-351202
G2/M Checkpoints R-HSA-69481
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ub-specific processing proteases R-HSA-5689880
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Stabilization of p53 R-HSA-69541
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent DNA Damage Response R-HSA-69610
Beta-catenin independent WNT signaling R-HSA-3858494
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Immune System R-HSA-168256
TCF dependent signaling in response to WNT R-HSA-201681
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Axon guidance R-HSA-422475
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Anaphase R-HSA-68882
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
Activation of NF-kappaB in B cells R-HSA-1169091
S Phase R-HSA-69242
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Programmed Cell Death R-HSA-5357801
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
Nervous system development R-HSA-9675108
Downstream TCR signaling R-HSA-202424
Post-translational protein modification R-HSA-597592
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Metabolism R-HSA-1430728
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
HIV Infection R-HSA-162906
Cellular response to hypoxia R-HSA-1234174
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hedgehog ligand biogenesis R-HSA-5358346
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
Defective CFTR causes cystic fibrosis R-HSA-5678895
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of PTEN stability and activity R-HSA-8948751
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613

Expression Atlas ENSG00000108671
NCBI gene (formerly Entrezgene) 5717
GeneCards 9556
HGNC Symbol HGNC:9556
MIM gene 604449
UniProtKB Gene Name O00231
WikiGene 5717
Ensembl ID : ENSG00000162889
Description: MAPK activated protein kinase 2
Gene Synonyms: MK2
1 APIs:
240 Possible Orthologues:

Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Immune System R-HSA-168256
MyD88 dependent cascade initiated on endosome R-HSA-975155
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Interleukin-17 signaling R-HSA-448424
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Fatty acid metabolism R-HSA-8978868
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MAP kinase activation R-HSA-450294
CREB phosphorylation R-HSA-199920
Signalling to RAS R-HSA-167044
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Metabolism of lipids R-HSA-556833
Signaling by NTRK1 (TRKA) R-HSA-187037
Cellular Senescence R-HSA-2559583
Cytokine Signaling in Immune system R-HSA-1280215
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Metabolism of RNA R-HSA-8953854
Innate Immune System R-HSA-168249
MyD88-independent TLR4 cascade R-HSA-166166
Cellular response to heat stress R-HSA-3371556
TNF signaling R-HSA-75893
Arachidonic acid metabolism R-HSA-2142753
p38MAPK events R-HSA-171007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular responses to stimuli R-HSA-8953897
Signalling to ERKs R-HSA-187687
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Regulation of TNFR1 signaling R-HSA-5357905
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NTRKs R-HSA-166520
Metabolism R-HSA-1430728
Toll-like Receptor Cascades R-HSA-168898
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
VEGFA-VEGFR2 Pathway R-HSA-4420097
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by VEGF R-HSA-194138
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Signalling to ERKs R-HSA-187687
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
TNF signaling R-HSA-75893
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Metabolism of RNA R-HSA-8953854
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular response to heat stress R-HSA-3371556
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
p38MAPK events R-HSA-171007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of lipids R-HSA-556833
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Regulation of TNFR1 signaling R-HSA-5357905
Signaling by Interleukins R-HSA-449147
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
CREB phosphorylation R-HSA-199920
Signaling by Interleukins R-HSA-449147
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Immune System R-HSA-168256
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Cytokine Signaling in Immune system R-HSA-1280215
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-17 signaling R-HSA-448424
Metabolism of lipids R-HSA-556833
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of RNA R-HSA-8953854
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Metabolism R-HSA-1430728
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by VEGF R-HSA-194138
MAP kinase activation R-HSA-450294
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88 dependent cascade initiated on endosome R-HSA-975155
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signalling to ERKs R-HSA-187687
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
p38MAPK events R-HSA-171007
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Innate Immune System R-HSA-168249
Cellular Senescence R-HSA-2559583
Signaling by NTRKs R-HSA-166520
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Arachidonic acid metabolism R-HSA-2142753
Cellular responses to stress R-HSA-2262752
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll-like Receptor Cascades R-HSA-168898
Fatty acid metabolism R-HSA-8978868
CREB phosphorylation R-HSA-199920
Death Receptor Signaling R-HSA-73887
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TNF signaling R-HSA-75893
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Cellular Senescence R-HSA-2559583
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Arachidonic acid metabolism R-HSA-2142753
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88-independent TLR4 cascade R-HSA-166166
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Metabolism of RNA R-HSA-8953854
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Immune System R-HSA-168256
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Oxidative Stress Induced Senescence R-HSA-2559580
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAP kinase activation R-HSA-450294
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by NTRKs R-HSA-166520
p38MAPK events R-HSA-171007
CREB phosphorylation R-HSA-199920
Fatty acid metabolism R-HSA-8978868
Signaling by VEGF R-HSA-194138
Regulation of TNFR1 signaling R-HSA-5357905
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular responses to stress R-HSA-2262752
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
TNF signaling R-HSA-75893
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Cellular response to heat stress R-HSA-3371556
Signal Transduction R-HSA-162582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-17 signaling R-HSA-448424
Death Receptor Signaling R-HSA-73887
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MyD88 cascade initiated on plasma membrane R-HSA-975871
Metabolism of lipids R-HSA-556833
Signalling to ERKs R-HSA-187687
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
VEGFA-VEGFR2 Pathway R-HSA-4420097
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signalling to RAS R-HSA-167044
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNF signaling R-HSA-75893
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Signaling by NTRKs R-HSA-166520
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signalling to ERKs R-HSA-187687
Arachidonic acid metabolism R-HSA-2142753
Cellular Senescence R-HSA-2559583
Regulation of TNFR1 signaling R-HSA-5357905
Cellular responses to stress R-HSA-2262752
VEGFA-VEGFR2 Pathway R-HSA-4420097
Interleukin-17 signaling R-HSA-448424
Signaling by NTRK1 (TRKA) R-HSA-187037
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Signaling by Interleukins R-HSA-449147
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signal Transduction R-HSA-162582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Innate Immune System R-HSA-168249
Metabolism of RNA R-HSA-8953854
Signalling to RAS R-HSA-167044
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CREB phosphorylation R-HSA-199920
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MAP kinase activation R-HSA-450294
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by VEGF R-HSA-194138
Cytokine Signaling in Immune system R-HSA-1280215
p38MAPK events R-HSA-171007
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88-independent TLR4 cascade R-HSA-166166
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular response to heat stress R-HSA-3371556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
MyD88 dependent cascade initiated on endosome R-HSA-975155
Arachidonic acid metabolism R-HSA-2142753
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TNF signaling R-HSA-75893
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by NTRKs R-HSA-166520
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism R-HSA-1430728
Fatty acid metabolism R-HSA-8978868
Cellular responses to stress R-HSA-2262752
Death Receptor Signaling R-HSA-73887
Signaling by VEGF R-HSA-194138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
p38MAPK events R-HSA-171007
Signalling to RAS R-HSA-167044
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular Senescence R-HSA-2559583
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAP kinase activation R-HSA-450294
Regulation of TNFR1 signaling R-HSA-5357905
Signal Transduction R-HSA-162582
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 cascade initiated on plasma membrane R-HSA-975871
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of lipids R-HSA-556833
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signalling to ERKs R-HSA-187687
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular responses to stimuli R-HSA-8953897
CREB phosphorylation R-HSA-199920
Metabolism of RNA R-HSA-8953854
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
MAP kinase activation R-HSA-450294
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signalling to ERKs R-HSA-187687
Metabolism of lipids R-HSA-556833
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Innate Immune System R-HSA-168249
Interleukin-17 signaling R-HSA-448424
Signaling by NTRKs R-HSA-166520
Death Receptor Signaling R-HSA-73887
Cellular response to heat stress R-HSA-3371556
Signal Transduction R-HSA-162582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Signaling by VEGF R-HSA-194138
Cellular Senescence R-HSA-2559583
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Fatty acid metabolism R-HSA-8978868
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Interleukins R-HSA-449147
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Immune System R-HSA-168256
Signalling to RAS R-HSA-167044
MyD88-independent TLR4 cascade R-HSA-166166
Metabolism of RNA R-HSA-8953854
Oxidative Stress Induced Senescence R-HSA-2559580
p38MAPK events R-HSA-171007
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Arachidonic acid metabolism R-HSA-2142753
Regulation of TNFR1 signaling R-HSA-5357905
CREB phosphorylation R-HSA-199920
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cellular responses to stimuli R-HSA-8953897
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Metabolism of lipids R-HSA-556833
Signaling by NTRKs R-HSA-166520
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-17 signaling R-HSA-448424
TNF signaling R-HSA-75893
Fatty acid metabolism R-HSA-8978868
Signaling by NTRK1 (TRKA) R-HSA-187037
Signalling to RAS R-HSA-167044
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
VEGFA-VEGFR2 Pathway R-HSA-4420097
MyD88-independent TLR4 cascade R-HSA-166166
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signalling to ERKs R-HSA-187687
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
Metabolism R-HSA-1430728
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Arachidonic acid metabolism R-HSA-2142753
p38MAPK events R-HSA-171007
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular Senescence R-HSA-2559583
Immune System R-HSA-168256
CREB phosphorylation R-HSA-199920
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Signaling by Interleukins R-HSA-449147
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
Toll-like Receptor Cascades R-HSA-168898
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
p38MAPK events R-HSA-171007
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of lipids R-HSA-556833
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Arachidonic acid metabolism R-HSA-2142753
Cellular Senescence R-HSA-2559583
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by NTRK1 (TRKA) R-HSA-187037
Cellular response to heat stress R-HSA-3371556
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Death Receptor Signaling R-HSA-73887
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signalling to RAS R-HSA-167044
Oxidative Stress Induced Senescence R-HSA-2559580
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MAP kinase activation R-HSA-450294
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Signalling to ERKs R-HSA-187687
Fatty acid metabolism R-HSA-8978868
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Signaling by VEGF R-HSA-194138
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
TNF signaling R-HSA-75893
Metabolism of RNA R-HSA-8953854
CREB phosphorylation R-HSA-199920
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Arachidonic acid metabolism R-HSA-2142753
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Death Receptor Signaling R-HSA-73887
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
CREB phosphorylation R-HSA-199920
Signaling by NTRKs R-HSA-166520
Cellular response to heat stress R-HSA-3371556
Toll-like Receptor Cascades R-HSA-168898
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stress R-HSA-2262752
MyD88-independent TLR4 cascade R-HSA-166166
TNF signaling R-HSA-75893
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of TNFR1 signaling R-HSA-5357905
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
p38MAPK events R-HSA-171007
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Metabolism R-HSA-1430728
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513
Interleukin-17 signaling R-HSA-448424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Metabolism of RNA R-HSA-8953854
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by VEGF R-HSA-194138
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular Senescence R-HSA-2559583
Signalling to RAS R-HSA-167044
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164

Expression Atlas ENSG00000162889
NCBI gene (formerly Entrezgene) 9261
GeneCards 6887
HGNC Symbol HGNC:6887
MIM gene 602006
UniProtKB Gene Name P49137
WikiGene 9261
Gene: PIM1
Ensembl ID : ENSG00000137193
Description: Pim-1 proto-oncogene, serine/threonine kinase
Gene Synonyms: PIM
3 APIs:
248 Possible Orthologues:

Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FLT3 fusion proteins R-HSA-9703465
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
Signaling by FLT3 fusion proteins R-HSA-9703465
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
FLT3 signaling in disease R-HSA-9682385
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Disease R-HSA-1643685
FLT3 signaling in disease R-HSA-9682385
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Immune System R-HSA-168256
Signaling by FLT3 fusion proteins R-HSA-9703465
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
FLT3 signaling in disease R-HSA-9682385
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by FLT3 fusion proteins R-HSA-9703465
FLT3 signaling in disease R-HSA-9682385
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Immune System R-HSA-168256
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FLT3 fusion proteins R-HSA-9703465
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Interleukins R-HSA-449147
FLT3 signaling in disease R-HSA-9682385
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Signaling by FLT3 fusion proteins R-HSA-9703465
Immune System R-HSA-168256
FLT3 signaling in disease R-HSA-9682385
Disease R-HSA-1643685
Signaling by FLT3 fusion proteins R-HSA-9703465
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147

Expression Atlas ENSG00000137193
NCBI gene (formerly Entrezgene) 5292
GeneCards 8986
HGNC Symbol HGNC:8986
MIM gene 164960
UniProtKB Gene Name P11309
WikiGene 5292