Gene: PNP
Ensembl ID : ENSG00000198805
Description: purine nucleoside phosphorylase
Gene Synonyms: NP,PUNP
1 APIs:
123 Possible Orthologues:

Purine salvage R-HSA-74217
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Neutrophil degranulation R-HSA-6798695
Nucleotide catabolism defects R-HSA-9735786
Innate Immune System R-HSA-168249
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Diseases of nucleotide metabolism R-HSA-9735804
Ribavirin ADME R-HSA-9755088
Drug ADME R-HSA-9748784
Immune System R-HSA-168256
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Nucleotide salvage R-HSA-8956321
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Innate Immune System R-HSA-168249
Metabolism of nucleotides R-HSA-15869
Diseases of nucleotide metabolism R-HSA-9735804
Drug ADME R-HSA-9748784
Purine catabolism R-HSA-74259
Ribavirin ADME R-HSA-9755088
Neutrophil degranulation R-HSA-6798695
Nucleotide catabolism defects R-HSA-9735786
Immune System R-HSA-168256
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Diseases of metabolism R-HSA-5668914
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Purine salvage R-HSA-74217
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Disease R-HSA-1643685
Nucleotide catabolism R-HSA-8956319
Nucleotide catabolism defects R-HSA-9735786
Purine catabolism R-HSA-74259
Diseases of metabolism R-HSA-5668914
Innate Immune System R-HSA-168249
Metabolism of nucleotides R-HSA-15869
Purine salvage R-HSA-74217
Nucleotide salvage R-HSA-8956321
Drug ADME R-HSA-9748784
Diseases of nucleotide metabolism R-HSA-9735804
Ribavirin ADME R-HSA-9755088
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism defects R-HSA-9735786
Drug ADME R-HSA-9748784
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Diseases of nucleotide metabolism R-HSA-9735804
Immune System R-HSA-168256
Ribavirin ADME R-HSA-9755088
Purine catabolism R-HSA-74259
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Nucleotide catabolism R-HSA-8956319
Neutrophil degranulation R-HSA-6798695
Nucleotide salvage R-HSA-8956321
Diseases of metabolism R-HSA-5668914
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Ribavirin ADME R-HSA-9755088
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Innate Immune System R-HSA-168249
Diseases of metabolism R-HSA-5668914
Purine salvage R-HSA-74217
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Purine catabolism R-HSA-74259
Diseases of nucleotide metabolism R-HSA-9735804
Metabolism R-HSA-1430728
Drug ADME R-HSA-9748784
Innate Immune System R-HSA-168249
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Ribavirin ADME R-HSA-9755088
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Immune System R-HSA-168256
Diseases of nucleotide metabolism R-HSA-9735804
Disease R-HSA-1643685
Nucleotide salvage R-HSA-8956321
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Drug ADME R-HSA-9748784
Diseases of metabolism R-HSA-5668914
Neutrophil degranulation R-HSA-6798695
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Nucleotide salvage R-HSA-8956321
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Drug ADME R-HSA-9748784
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Diseases of metabolism R-HSA-5668914
Ribavirin ADME R-HSA-9755088
Innate Immune System R-HSA-168249
Nucleotide catabolism defects R-HSA-9735786
Purine salvage R-HSA-74217
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Diseases of nucleotide metabolism R-HSA-9735804
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Ribavirin ADME R-HSA-9755088
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Drug ADME R-HSA-9748784
Diseases of nucleotide metabolism R-HSA-9735804
Diseases of metabolism R-HSA-5668914
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321

Expression Atlas ENSG00000198805
LRG display in Ensembl gene LRG_91
NCBI gene (formerly Entrezgene) 4860
GeneCards 7892
HGNC Symbol HGNC:7892
MIM gene 164050
MIM morbid 613179
UniProtKB Gene Name V9HWH6
WikiGene 4860
Gene: CDK9
Ensembl ID : ENSG00000136807
Description: cyclin dependent kinase 9
Gene Synonyms: C-2K,CDC2L4,PITALRE,TAK
7 APIs:
207 Possible Orthologues:

HIV elongation arrest and recovery R-HSA-167287
Signaling by TGFB family members R-HSA-9006936
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
HIV Life Cycle R-HSA-162587
RNA polymerase II transcribes snRNA genes R-HSA-6807505
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Transcriptional Regulation by TP53 R-HSA-3700989
Estrogen-dependent gene expression R-HSA-9018519
Pausing and recovery of HIV elongation R-HSA-167290
RNA Polymerase II Transcription Elongation R-HSA-75955
Late Phase of HIV Life Cycle R-HSA-162599
HIV Transcription Elongation R-HSA-167169
RNA Polymerase II Transcription R-HSA-73857
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Generic Transcription Pathway R-HSA-212436
HIV Infection R-HSA-162906
Signaling by TGF-beta Receptor Complex R-HSA-170834
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Disease R-HSA-1643685
RNA Polymerase II Pre-transcription Events R-HSA-674695
Formation of RNA Pol II elongation complex R-HSA-112382
ESR-mediated signaling R-HSA-8939211
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Infectious disease R-HSA-5663205
Interactions of Tat with host cellular proteins R-HSA-176034
Host Interactions of HIV factors R-HSA-162909
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Transcription of the HIV genome R-HSA-167172
Signaling by Nuclear Receptors R-HSA-9006931
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Transcriptional Regulation by TP53 R-HSA-3700989
HIV Transcription Elongation R-HSA-167169
Infectious disease R-HSA-5663205
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
HIV Infection R-HSA-162906
Signaling by TGF-beta Receptor Complex R-HSA-170834
Transcription of the HIV genome R-HSA-167172
RNA Polymerase II Transcription Elongation R-HSA-75955
Generic Transcription Pathway R-HSA-212436
ESR-mediated signaling R-HSA-8939211
HIV Life Cycle R-HSA-162587
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Estrogen-dependent gene expression R-HSA-9018519
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Late Phase of HIV Life Cycle R-HSA-162599
RNA Polymerase II Transcription R-HSA-73857
RNA polymerase II transcribes snRNA genes R-HSA-6807505
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Formation of RNA Pol II elongation complex R-HSA-112382
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by TGFB family members R-HSA-9006936
Interactions of Tat with host cellular proteins R-HSA-176034
Pausing and recovery of HIV elongation R-HSA-167290
Disease R-HSA-1643685
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Pre-transcription Events R-HSA-674695
Signal Transduction R-HSA-162582
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
HIV elongation arrest and recovery R-HSA-167287
Host Interactions of HIV factors R-HSA-162909
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
RNA polymerase II transcribes snRNA genes R-HSA-6807505
HIV Transcription Elongation R-HSA-167169
Infectious disease R-HSA-5663205
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Formation of RNA Pol II elongation complex R-HSA-112382
HIV Life Cycle R-HSA-162587
Late Phase of HIV Life Cycle R-HSA-162599
Disease R-HSA-1643685
Signaling by Nuclear Receptors R-HSA-9006931
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
RNA Polymerase II Transcription R-HSA-73857
ESR-mediated signaling R-HSA-8939211
Signaling by TGFB family members R-HSA-9006936
Host Interactions of HIV factors R-HSA-162909
HIV Infection R-HSA-162906
Pausing and recovery of HIV elongation R-HSA-167290
Transcription of the HIV genome R-HSA-167172
Estrogen-dependent gene expression R-HSA-9018519
HIV elongation arrest and recovery R-HSA-167287
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Interactions of Tat with host cellular proteins R-HSA-176034
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
RNA Polymerase II Pre-transcription Events R-HSA-674695
Signaling by TGF-beta Receptor Complex R-HSA-170834
RNA Polymerase II Transcription Elongation R-HSA-75955
Generic Transcription Pathway R-HSA-212436
Signal Transduction R-HSA-162582
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
HIV Infection R-HSA-162906
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Interactions of Tat with host cellular proteins R-HSA-176034
HIV Transcription Elongation R-HSA-167169
HIV Life Cycle R-HSA-162587
Formation of RNA Pol II elongation complex R-HSA-112382
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Estrogen-dependent gene expression R-HSA-9018519
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Late Phase of HIV Life Cycle R-HSA-162599
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
HIV elongation arrest and recovery R-HSA-167287
Signaling by TGFB family members R-HSA-9006936
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
RNA Polymerase II Pre-transcription Events R-HSA-674695
ESR-mediated signaling R-HSA-8939211
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signal Transduction R-HSA-162582
Pausing and recovery of HIV elongation R-HSA-167290
RNA Polymerase II Transcription Elongation R-HSA-75955
Signaling by TGF-beta Receptor Complex R-HSA-170834
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Nuclear Receptors R-HSA-9006931
Transcription of the HIV genome R-HSA-167172
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Host Interactions of HIV factors R-HSA-162909
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Pausing and recovery of HIV elongation R-HSA-167290
Interactions of Tat with host cellular proteins R-HSA-176034
HIV Transcription Elongation R-HSA-167169
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
HIV Life Cycle R-HSA-162587
Signaling by Nuclear Receptors R-HSA-9006931
HIV Infection R-HSA-162906
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
RNA Polymerase II Pre-transcription Events R-HSA-674695
RNA Polymerase II Transcription Elongation R-HSA-75955
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Disease R-HSA-1643685
Estrogen-dependent gene expression R-HSA-9018519
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Signaling by TGF-beta Receptor Complex R-HSA-170834
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Transcription of the HIV genome R-HSA-167172
Formation of RNA Pol II elongation complex R-HSA-112382
Signaling by TGFB family members R-HSA-9006936
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Infectious disease R-HSA-5663205
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
HIV elongation arrest and recovery R-HSA-167287
ESR-mediated signaling R-HSA-8939211
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Late Phase of HIV Life Cycle R-HSA-162599
Signal Transduction R-HSA-162582
HIV Transcription Elongation R-HSA-167169
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Interactions of Tat with host cellular proteins R-HSA-176034
Formation of RNA Pol II elongation complex R-HSA-112382
Signaling by Nuclear Receptors R-HSA-9006931
Late Phase of HIV Life Cycle R-HSA-162599
ESR-mediated signaling R-HSA-8939211
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by TGFB family members R-HSA-9006936
Generic Transcription Pathway R-HSA-212436
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Disease R-HSA-1643685
Transcription of the HIV genome R-HSA-167172
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
Pausing and recovery of HIV elongation R-HSA-167290
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription Elongation R-HSA-75955
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Signal Transduction R-HSA-162582
Infectious disease R-HSA-5663205
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Estrogen-dependent gene expression R-HSA-9018519
HIV Life Cycle R-HSA-162587
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Host Interactions of HIV factors R-HSA-162909
Signaling by TGF-beta Receptor Complex R-HSA-170834
HIV elongation arrest and recovery R-HSA-167287
RNA Polymerase II Pre-transcription Events R-HSA-674695
Transcription of the HIV genome R-HSA-167172
Generic Transcription Pathway R-HSA-212436
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Transcriptional Regulation by TP53 R-HSA-3700989
Disease R-HSA-1643685
RNA Polymerase II Pre-transcription Events R-HSA-674695
Signaling by Nuclear Receptors R-HSA-9006931
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Signal Transduction R-HSA-162582
ESR-mediated signaling R-HSA-8939211
Formation of RNA Pol II elongation complex R-HSA-112382
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Late Phase of HIV Life Cycle R-HSA-162599
RNA Polymerase II Transcription Elongation R-HSA-75955
Pausing and recovery of HIV elongation R-HSA-167290
HIV elongation arrest and recovery R-HSA-167287
Signaling by TGF-beta Receptor Complex R-HSA-170834
HIV Life Cycle R-HSA-162587
HIV Infection R-HSA-162906
Interactions of Tat with host cellular proteins R-HSA-176034
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Estrogen-dependent gene expression R-HSA-9018519
Infectious disease R-HSA-5663205
Signaling by TGFB family members R-HSA-9006936
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
HIV Transcription Elongation R-HSA-167169
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
RNA Polymerase II Pre-transcription Events R-HSA-674695
Signaling by TGFB family members R-HSA-9006936
HIV Infection R-HSA-162906
Host Interactions of HIV factors R-HSA-162909
Signal Transduction R-HSA-162582
Formation of RNA Pol II elongation complex R-HSA-112382
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Transcriptional Regulation by TP53 R-HSA-3700989
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Estrogen-dependent gene expression R-HSA-9018519
Signaling by TGF-beta Receptor Complex R-HSA-170834
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Infectious disease R-HSA-5663205
HIV Life Cycle R-HSA-162587
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
RNA Polymerase II Transcription Elongation R-HSA-75955
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
HIV elongation arrest and recovery R-HSA-167287
Pausing and recovery of HIV elongation R-HSA-167290
Gene expression (Transcription) R-HSA-74160
Signaling by Nuclear Receptors R-HSA-9006931
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
ESR-mediated signaling R-HSA-8939211
Transcription of the HIV genome R-HSA-167172
Interactions of Tat with host cellular proteins R-HSA-176034
HIV Transcription Elongation R-HSA-167169
Late Phase of HIV Life Cycle R-HSA-162599
Pausing and recovery of HIV elongation R-HSA-167290
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by TGFB family members R-HSA-9006936
Transcription of the HIV genome R-HSA-167172
Signaling by TGF-beta Receptor Complex R-HSA-170834
HIV Life Cycle R-HSA-162587
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
ESR-mediated signaling R-HSA-8939211
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Signal Transduction R-HSA-162582
Interactions of Tat with host cellular proteins R-HSA-176034
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
HIV Transcription Elongation R-HSA-167169
Estrogen-dependent gene expression R-HSA-9018519
RNA Polymerase II Pre-transcription Events R-HSA-674695
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Disease R-HSA-1643685
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription Elongation R-HSA-75955
Generic Transcription Pathway R-HSA-212436
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Formation of RNA Pol II elongation complex R-HSA-112382
HIV Infection R-HSA-162906
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
HIV elongation arrest and recovery R-HSA-167287
Late Phase of HIV Life Cycle R-HSA-162599
Formation of RNA Pol II elongation complex R-HSA-112382
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Pausing and recovery of HIV elongation R-HSA-167290
Generic Transcription Pathway R-HSA-212436
Signaling by TGF-beta Receptor Complex R-HSA-170834
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Signaling by Nuclear Receptors R-HSA-9006931
Late Phase of HIV Life Cycle R-HSA-162599
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
HIV Infection R-HSA-162906
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
Signaling by TGFB family members R-HSA-9006936
RNA Polymerase II Transcription R-HSA-73857
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Transcription of the HIV genome R-HSA-167172
Estrogen-dependent gene expression R-HSA-9018519
Signal Transduction R-HSA-162582
Host Interactions of HIV factors R-HSA-162909
HIV elongation arrest and recovery R-HSA-167287
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
HIV Life Cycle R-HSA-162587
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
RNA Polymerase II Transcription Elongation R-HSA-75955
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
HIV Transcription Elongation R-HSA-167169
Interactions of Tat with host cellular proteins R-HSA-176034
RNA Polymerase II Pre-transcription Events R-HSA-674695
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Transcriptional Regulation by TP53 R-HSA-3700989
Estrogen-dependent gene expression R-HSA-9018519
RNA Polymerase II Pre-transcription Events R-HSA-674695
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Transcription of the HIV genome R-HSA-167172
Pausing and recovery of HIV elongation R-HSA-167290
Tat-mediated HIV elongation arrest and recovery R-HSA-167243
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200
Host Interactions of HIV factors R-HSA-162909
Late Phase of HIV Life Cycle R-HSA-162599
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246
ESR-mediated signaling R-HSA-8939211
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signal Transduction R-HSA-162582
RNA polymerase II transcribes snRNA genes R-HSA-6807505
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152
HIV elongation arrest and recovery R-HSA-167287
HIV Infection R-HSA-162906
Signaling by TGFB family members R-HSA-9006936
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238
Formation of RNA Pol II elongation complex R-HSA-112382
Signaling by TGF-beta Receptor Complex R-HSA-170834
RNA Polymerase II Transcription Elongation R-HSA-75955
RNA Polymerase II Transcription R-HSA-73857
HIV Transcription Elongation R-HSA-167169
Signaling by Nuclear Receptors R-HSA-9006931
Interactions of Tat with host cellular proteins R-HSA-176034
HIV Life Cycle R-HSA-162587
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Infectious disease R-HSA-5663205

Expression Atlas ENSG00000136807
NCBI gene (formerly Entrezgene) 1025
GeneCards 1780
HGNC Symbol HGNC:1780
MIM gene 603251
UniProtKB Gene Name X6RE90
WikiGene 1025
Gene: MALT1
Ensembl ID : ENSG00000172175
Description: MALT1 paracaspase
Gene Synonyms: MLT,PCASP1
1 APIs:
197 Possible Orthologues:

Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Immune System R-HSA-168256
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
CLEC7A/inflammasome pathway R-HSA-5660668
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A/inflammasome pathway R-HSA-5660668
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A/inflammasome pathway R-HSA-5660668
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TCR signaling R-HSA-202403
CLEC7A/inflammasome pathway R-HSA-5660668
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of NF-kappaB in B cells R-HSA-1169091
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream TCR signaling R-HSA-202424

Expression Atlas ENSG00000172175
LRG display in Ensembl gene LRG_1221
NCBI gene (formerly Entrezgene) 10892
GeneCards 6819
HGNC Symbol HGNC:6819
MIM gene 604860
MIM morbid 615468
UniProtKB Gene Name Q9UDY8
WikiGene 10892
Gene: PLG
Ensembl ID : ENSG00000122194
Description: plasminogen
Gene Synonyms:
12 APIs:
263 Possible Orthologues:

Signaling by PDGF R-HSA-186797
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Platelet degranulation R-HSA-114608
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Degradation of the extracellular matrix R-HSA-1474228
Dissolution of Fibrin Clot R-HSA-75205
Degradation of the extracellular matrix R-HSA-1474228
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by PDGF R-HSA-186797
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Extracellular matrix organization R-HSA-1474244
Platelet degranulation R-HSA-114608
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Degradation of the extracellular matrix R-HSA-1474228
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Platelet degranulation R-HSA-114608
Signal Transduction R-HSA-162582
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of proteins R-HSA-392499
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Dissolution of Fibrin Clot R-HSA-75205
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Platelet degranulation R-HSA-114608
Signaling by PDGF R-HSA-186797
Hemostasis R-HSA-109582
Platelet activation, signaling and aggregation R-HSA-76002
Metabolism of proteins R-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Activation of Matrix Metalloproteinases R-HSA-1592389
Dissolution of Fibrin Clot R-HSA-75205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Extracellular matrix organization R-HSA-1474244
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Activation of Matrix Metalloproteinases R-HSA-1592389
Platelet degranulation R-HSA-114608
Extracellular matrix organization R-HSA-1474244
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism of proteins R-HSA-392499
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Dissolution of Fibrin Clot R-HSA-75205
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Degradation of the extracellular matrix R-HSA-1474228
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by PDGF R-HSA-186797
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Activation of Matrix Metalloproteinases R-HSA-1592389
Hemostasis R-HSA-109582
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signal Transduction R-HSA-162582
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Dissolution of Fibrin Clot R-HSA-75205
Metabolism of proteins R-HSA-392499
Platelet degranulation R-HSA-114608
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet activation, signaling and aggregation R-HSA-76002
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Extracellular matrix organization R-HSA-1474244
Signaling by PDGF R-HSA-186797
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Degradation of the extracellular matrix R-HSA-1474228
Hemostasis R-HSA-109582
Platelet degranulation R-HSA-114608
Metabolism of proteins R-HSA-392499
Activation of Matrix Metalloproteinases R-HSA-1592389
Signal Transduction R-HSA-162582
Dissolution of Fibrin Clot R-HSA-75205
Metabolism of proteins R-HSA-392499
Hemostasis R-HSA-109582
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Signaling by PDGF R-HSA-186797
Platelet activation, signaling and aggregation R-HSA-76002
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Dissolution of Fibrin Clot R-HSA-75205
Platelet degranulation R-HSA-114608
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Activation of Matrix Metalloproteinases R-HSA-1592389
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Degradation of the extracellular matrix R-HSA-1474228
Platelet degranulation R-HSA-114608
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Signaling by PDGF R-HSA-186797
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Dissolution of Fibrin Clot R-HSA-75205
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Activation of Matrix Metalloproteinases R-HSA-1592389
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Platelet activation, signaling and aggregation R-HSA-76002
Signal Transduction R-HSA-162582
Platelet degranulation R-HSA-114608
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGF R-HSA-186797
Response to elevated platelet cytosolic Ca2+ R-HSA-76005
Hemostasis R-HSA-109582
Dissolution of Fibrin Clot R-HSA-75205
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426
Metabolism of proteins R-HSA-392499

Expression Atlas ENSG00000122194
LRG display in Ensembl gene LRG_571
NCBI gene (formerly Entrezgene) 5340
GeneCards 9071
HGNC Symbol HGNC:9071
MIM gene 173350
MIM morbid 619360
UniProtKB Gene Name Q5TEH5
WikiGene 5340
Gene: NT5E
Ensembl ID : ENSG00000135318
Description: 5'-nucleotidase ecto
Gene Synonyms: CALJA,CD73,EN,ENT,NT5
1 APIs:
250 Possible Orthologues:

Nucleotide catabolism R-HSA-8956319
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Infectious disease R-HSA-5663205
Metabolism of vitamins and cofactors R-HSA-196854
Purine catabolism R-HSA-74259
Nicotinate metabolism R-HSA-196807
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Metabolism of vitamins and cofactors R-HSA-196854
Nicotinate metabolism R-HSA-196807
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Infectious disease R-HSA-5663205
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Purine catabolism R-HSA-74259
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Metabolism of vitamins and cofactors R-HSA-196854
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Pyrimidine catabolism R-HSA-73621
Leishmania infection R-HSA-9658195
Infectious disease R-HSA-5663205
Metabolism of nucleotides R-HSA-15869
Metabolism of vitamins and cofactors R-HSA-196854
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Metabolism R-HSA-1430728
Nicotinate metabolism R-HSA-196807
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nucleotide catabolism R-HSA-8956319
Disease R-HSA-1643685
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Metabolism of vitamins and cofactors R-HSA-196854
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Infectious disease R-HSA-5663205
Nicotinate metabolism R-HSA-196807
Metabolism of vitamins and cofactors R-HSA-196854
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Infectious disease R-HSA-5663205
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Purine catabolism R-HSA-74259
Pyrimidine catabolism R-HSA-73621
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of nucleotides R-HSA-15869
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Purine catabolism R-HSA-74259
Leishmania infection R-HSA-9658195
Metabolism of vitamins and cofactors R-HSA-196854
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Disease R-HSA-1643685
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Infectious disease R-HSA-5663205
Purine catabolism R-HSA-74259
Metabolism of vitamins and cofactors R-HSA-196854
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nicotinate metabolism R-HSA-196807
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism of nucleotides R-HSA-15869
Disease R-HSA-1643685
Nucleotide catabolism R-HSA-8956319
Metabolism of vitamins and cofactors R-HSA-196854
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Infectious disease R-HSA-5663205
Purine catabolism R-HSA-74259
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Leishmania infection R-HSA-9658195

Expression Atlas ENSG00000135318
NCBI gene (formerly Entrezgene) 4907
GeneCards 8021
HGNC Symbol HGNC:8021
MIM gene 129190
MIM morbid 211800
UniProtKB Gene Name Q96B60
WikiGene 4907
Gene: PSMB4
Ensembl ID : ENSG00000159377
Description: proteasome 20S subunit beta 4
Gene Synonyms: HN3,PROS26
6 APIs:
214 Possible Orthologues:

UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
Ub-specific processing proteases R-HSA-5689880
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
S Phase R-HSA-69242
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
RNA Polymerase II Transcription R-HSA-73857
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
ER-Phagosome pathway R-HSA-1236974
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
HIV Infection R-HSA-162906
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
S Phase R-HSA-69242
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
C-type lectin receptors (CLRs) R-HSA-5621481
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Antigen processing-Cross presentation R-HSA-1236975
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Negative regulation of NOTCH4 signaling R-HSA-9604323
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
PCP/CE pathway R-HSA-4086400
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Cell Cycle R-HSA-1640170
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Metabolism R-HSA-1430728
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog ligand biogenesis R-HSA-5358346
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
CLEC7A (Dectin-1) signaling R-HSA-5607764
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000159377
NCBI gene (formerly Entrezgene) 5692
GeneCards 9541
HGNC Symbol HGNC:9541
MIM gene 602177
MIM morbid 617591
UniProtKB Gene Name P28070
WikiGene 5692
Gene: PPP3CA
Ensembl ID : ENSG00000138814
Description: protein phosphatase 3 catalytic subunit alpha
Gene Synonyms: CALN,CALNA,CNA1,PPP2B
1 APIs:
230 Possible Orthologues:

GPCR downstream signalling R-HSA-388396
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Calcineurin activates NFAT R-HSA-2025928
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated Ca+2 mobilization R-HSA-2871809
DARPP-32 events R-HSA-180024
Beta-catenin independent WNT signaling R-HSA-3858494
Opioid Signalling R-HSA-111885
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Adaptive Immune System R-HSA-1280218
G alpha (i) signalling events R-HSA-418594
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ca2+ pathway R-HSA-4086398
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by GPCR R-HSA-372790
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A (Dectin-1) signaling R-HSA-5607764
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
Signaling by WNT R-HSA-195721
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Immune System R-HSA-168256
Beta-catenin independent WNT signaling R-HSA-3858494
Innate Immune System R-HSA-168249
Ca2+ pathway R-HSA-4086398
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Signal Transduction R-HSA-162582
Calcineurin activates NFAT R-HSA-2025928
G alpha (i) signalling events R-HSA-418594
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated Ca+2 mobilization R-HSA-2871809
Beta-catenin independent WNT signaling R-HSA-3858494
Immune System R-HSA-168256
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by GPCR R-HSA-372790
Opioid Signalling R-HSA-111885
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
Calcineurin activates NFAT R-HSA-2025928
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated Ca+2 mobilization R-HSA-2871809
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by GPCR R-HSA-372790
Beta-catenin independent WNT signaling R-HSA-3858494
Opioid Signalling R-HSA-111885
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
DARPP-32 events R-HSA-180024
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
GPCR downstream signalling R-HSA-388396
FCERI mediated Ca+2 mobilization R-HSA-2871809
Calcineurin activates NFAT R-HSA-2025928
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by WNT R-HSA-195721
Immune System R-HSA-168256
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by WNT R-HSA-195721
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
G alpha (i) signalling events R-HSA-418594
FCERI mediated Ca+2 mobilization R-HSA-2871809
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by GPCR R-HSA-372790
Innate Immune System R-HSA-168249
DARPP-32 events R-HSA-180024
C-type lectin receptors (CLRs) R-HSA-5621481
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GPCR downstream signalling R-HSA-388396
Beta-catenin independent WNT signaling R-HSA-3858494
Calcineurin activates NFAT R-HSA-2025928
Opioid Signalling R-HSA-111885
Adaptive Immune System R-HSA-1280218
Ca2+ pathway R-HSA-4086398
Signal Transduction R-HSA-162582
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
Opioid Signalling R-HSA-111885
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated Ca+2 mobilization R-HSA-2871809
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Calcineurin activates NFAT R-HSA-2025928
Signaling by WNT R-HSA-195721
Signaling by GPCR R-HSA-372790
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Beta-catenin independent WNT signaling R-HSA-3858494
DARPP-32 events R-HSA-180024
GPCR downstream signalling R-HSA-388396
Ca2+ pathway R-HSA-4086398
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G alpha (i) signalling events R-HSA-418594
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Opioid Signalling R-HSA-111885
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FCERI mediated Ca+2 mobilization R-HSA-2871809
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
GPCR downstream signalling R-HSA-388396
Adaptive Immune System R-HSA-1280218
Calcineurin activates NFAT R-HSA-2025928
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
DARPP-32 events R-HSA-180024
Signaling by WNT R-HSA-195721
Opioid Signalling R-HSA-111885
FCERI mediated Ca+2 mobilization R-HSA-2871809
Signal Transduction R-HSA-162582
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Beta-catenin independent WNT signaling R-HSA-3858494
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by GPCR R-HSA-372790
Signaling by WNT R-HSA-195721
DARPP-32 events R-HSA-180024
Immune System R-HSA-168256
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
CLEC7A (Dectin-1) signaling R-HSA-5607764
Calcineurin activates NFAT R-HSA-2025928
Innate Immune System R-HSA-168249
Ca2+ pathway R-HSA-4086398
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
FCERI mediated Ca+2 mobilization R-HSA-2871809
DARPP-32 events R-HSA-180024
Signaling by WNT R-HSA-195721
Ca2+ pathway R-HSA-4086398
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signal Transduction R-HSA-162582
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763
CLEC7A (Dectin-1) signaling R-HSA-5607764
Beta-catenin independent WNT signaling R-HSA-3858494
Immune System R-HSA-168256
Signaling by GPCR R-HSA-372790
Calcineurin activates NFAT R-HSA-2025928
Opioid Signalling R-HSA-111885
G alpha (i) signalling events R-HSA-418594
Innate Immune System R-HSA-168249
GPCR downstream signalling R-HSA-388396

Expression Atlas ENSG00000138814
NCBI gene (formerly Entrezgene) 5530
GeneCards 9314
HGNC Symbol HGNC:9314
MIM gene 114105
MIM morbid 618265
UniProtKB Gene Name Q08209
WikiGene 5530
Gene: PDE5A
Ensembl ID : ENSG00000138735
Description: phosphodiesterase 5A
Gene Synonyms:
8 APIs:
208 Possible Orthologues:

Nitric oxide stimulates guanylate cyclase R-HSA-392154
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
Smooth Muscle Contraction R-HSA-445355
Muscle contraction R-HSA-397014
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOBTB1 GTPase cycle R-HSA-9013422
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
cGMP effects R-HSA-418457
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Signal Transduction R-HSA-162582
Platelet homeostasis R-HSA-418346
cGMP effects R-HSA-418457
Smooth Muscle Contraction R-HSA-445355
Hemostasis R-HSA-109582
RHO GTPase cycle R-HSA-9012999
RHOBTB1 GTPase cycle R-HSA-9013422
RHOBTB GTPase Cycle R-HSA-9706574
Muscle contraction R-HSA-397014
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
cGMP effects R-HSA-418457
Nitric oxide stimulates guanylate cyclase R-HSA-392154
RHO GTPase cycle R-HSA-9012999
RHOBTB1 GTPase cycle R-HSA-9013422
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Smooth Muscle Contraction R-HSA-445355
Muscle contraction R-HSA-397014
Signaling by Rho GTPases R-HSA-194315
RHOBTB GTPase Cycle R-HSA-9706574
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
RHOBTB GTPase Cycle R-HSA-9706574
Signal Transduction R-HSA-162582
Smooth Muscle Contraction R-HSA-445355
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
cGMP effects R-HSA-418457
Muscle contraction R-HSA-397014
RHOBTB1 GTPase cycle R-HSA-9013422
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
RHOBTB GTPase Cycle R-HSA-9706574
Smooth Muscle Contraction R-HSA-445355
Signal Transduction R-HSA-162582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582
Signaling by Rho GTPases R-HSA-194315
Muscle contraction R-HSA-397014
RHOBTB1 GTPase cycle R-HSA-9013422
Platelet homeostasis R-HSA-418346
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
RHO GTPase cycle R-HSA-9012999
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
Platelet homeostasis R-HSA-418346
cGMP effects R-HSA-418457
Smooth Muscle Contraction R-HSA-445355
Muscle contraction R-HSA-397014
RHOBTB1 GTPase cycle R-HSA-9013422
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOBTB GTPase Cycle R-HSA-9706574
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
cGMP effects R-HSA-418457
RHOBTB GTPase Cycle R-HSA-9706574
Smooth Muscle Contraction R-HSA-445355
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
Platelet homeostasis R-HSA-418346
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPase cycle R-HSA-9012999
RHO GTPase cycle R-HSA-9012999
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Muscle contraction R-HSA-397014
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Platelet homeostasis R-HSA-418346
Signal Transduction R-HSA-162582
Smooth Muscle Contraction R-HSA-445355
Hemostasis R-HSA-109582
RHOBTB1 GTPase cycle R-HSA-9013422
RHOBTB GTPase Cycle R-HSA-9706574
cGMP effects R-HSA-418457
Hemostasis R-HSA-109582
RHOBTB1 GTPase cycle R-HSA-9013422
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Smooth Muscle Contraction R-HSA-445355
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Signal Transduction R-HSA-162582
Muscle contraction R-HSA-397014
RHOBTB GTPase Cycle R-HSA-9706574
Platelet homeostasis R-HSA-418346
Signaling by Rho GTPases R-HSA-194315
cGMP effects R-HSA-418457
RHO GTPase cycle R-HSA-9012999
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Platelet homeostasis R-HSA-418346
Smooth Muscle Contraction R-HSA-445355
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOBTB1 GTPase cycle R-HSA-9013422
cGMP effects R-HSA-418457
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582

Expression Atlas ENSG00000138735
NCBI gene (formerly Entrezgene) 8654
GeneCards 8784
HGNC Symbol HGNC:8784
MIM gene 603310
UniProtKB Gene Name O76074
WikiGene 8654