Gene: AKR1B1
Ensembl ID : ENSG00000085662
Description: aldo-keto reductase family 1 member B
Gene Synonyms: ALDR1,AR
4 APIs:
391 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Metabolism of carbohydrates R-HSA-71387
Fructose biosynthesis R-HSA-5652227
Fructose metabolism R-HSA-5652084
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Pregnenolone biosynthesis R-HSA-196108
Fructose biosynthesis R-HSA-5652227
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroids R-HSA-8957322
Metabolism of carbohydrates R-HSA-71387
Fructose metabolism R-HSA-5652084
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Metabolism of steroids R-HSA-8957322
Pregnenolone biosynthesis R-HSA-196108
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Fructose biosynthesis R-HSA-5652227
Metabolism of carbohydrates R-HSA-71387
Metabolism R-HSA-1430728
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Fructose metabolism R-HSA-5652084
Fructose metabolism R-HSA-5652084
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Pregnenolone biosynthesis R-HSA-196108
Fructose biosynthesis R-HSA-5652227
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroid hormones R-HSA-196071
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Pregnenolone biosynthesis R-HSA-196108
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroid hormones R-HSA-196071
Fructose metabolism R-HSA-5652084
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Fructose biosynthesis R-HSA-5652227
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Metabolism of carbohydrates R-HSA-71387
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism of steroids R-HSA-8957322
Fructose metabolism R-HSA-5652084
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroid hormones R-HSA-196071
Fructose biosynthesis R-HSA-5652227
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833

Expression Atlas ENSG00000085662
NCBI gene (formerly Entrezgene) 231
GeneCards 381
HGNC Symbol HGNC:381
MIM gene 103880
UniProtKB Gene Name P15121
WikiGene 231
Gene: MAP3K11
Ensembl ID : ENSG00000173327
Description: mitogen-activated protein kinase kinase kinase 11
Gene Synonyms: MEKK11,MLK3,PTK1,SPRK
1 APIs:
184 Possible Orthologues:

RAF activation R-HSA-5673000
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHOV GTPase cycle R-HSA-9013424
RAF/MAP kinase cascade R-HSA-5673001
Oncogenic MAPK signaling R-HSA-6802957
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
RHO GTPase cycle R-HSA-9012999
Signaling by RAS mutants R-HSA-6802949
Disease R-HSA-1643685
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RHOG GTPase cycle R-HSA-9013408
MAPK family signaling cascades R-HSA-5683057
CDC42 GTPase cycle R-HSA-9013148
Signaling downstream of RAS mutants R-HSA-9649948
RAF activation R-HSA-5673000
MAPK1/MAPK3 signaling R-HSA-5684996
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOV GTPase cycle R-HSA-9013424
MAPK family signaling cascades R-HSA-5683057
Signaling by RAS mutants R-HSA-6802949
RAF/MAP kinase cascade R-HSA-5673001
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
CDC42 GTPase cycle R-HSA-9013148
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
RHOG GTPase cycle R-HSA-9013408
RHO GTPase cycle R-HSA-9012999
RAF activation R-HSA-5673000
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Rho GTPases R-HSA-194315
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling downstream of RAS mutants R-HSA-9649948
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF activation R-HSA-5673000
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CDC42 GTPase cycle R-HSA-9013148
Signaling by RAS mutants R-HSA-6802949
RHOG GTPase cycle R-HSA-9013408
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by Rho GTPases R-HSA-194315
Disease R-HSA-1643685
Oncogenic MAPK signaling R-HSA-6802957
Oncogenic MAPK signaling R-HSA-6802957
Signaling downstream of RAS mutants R-HSA-9649948
Signal Transduction R-HSA-162582
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF activation R-HSA-5673000
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHO GTPase cycle R-HSA-9012999
RAF/MAP kinase cascade R-HSA-5673001
CDC42 GTPase cycle R-HSA-9013148
RHOV GTPase cycle R-HSA-9013424
Signaling by RAS mutants R-HSA-6802949
RHO GTPase cycle R-HSA-9012999
Signal Transduction R-HSA-162582
RHOV GTPase cycle R-HSA-9013424
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
Signaling by RAS mutants R-HSA-6802949
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Oncogenic MAPK signaling R-HSA-6802957
CDC42 GTPase cycle R-HSA-9013148
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by Rho GTPases R-HSA-194315
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
CDC42 GTPase cycle R-HSA-9013148
Signaling by RAS mutants R-HSA-6802949
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1/MAPK3 signaling R-HSA-5684996
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RHOG GTPase cycle R-HSA-9013408
Signaling by Rho GTPases R-HSA-194315
RHOV GTPase cycle R-HSA-9013424
Disease R-HSA-1643685
RHO GTPase cycle R-HSA-9012999
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
RAF activation R-HSA-5673000
Signal Transduction R-HSA-162582
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
CDC42 GTPase cycle R-HSA-9013148
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Signaling by RAS mutants R-HSA-6802949
Signaling downstream of RAS mutants R-HSA-9649948
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF activation R-HSA-5673000
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Signaling downstream of RAS mutants R-HSA-9649948
RAF activation R-HSA-5673000
RAF/MAP kinase cascade R-HSA-5673001
Signaling by RAS mutants R-HSA-6802949
RHOV GTPase cycle R-HSA-9013424
RHO GTPase cycle R-HSA-9012999
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Rho GTPases R-HSA-194315
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
CDC42 GTPase cycle R-HSA-9013148
RHOG GTPase cycle R-HSA-9013408
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
CDC42 GTPase cycle R-HSA-9013148
Signal Transduction R-HSA-162582
RAF activation R-HSA-5673000
Signaling downstream of RAS mutants R-HSA-9649948
RHOV GTPase cycle R-HSA-9013424
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Rho GTPases R-HSA-194315
RAF/MAP kinase cascade R-HSA-5673001
RHO GTPase cycle R-HSA-9012999
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RHOG GTPase cycle R-HSA-9013408
Signaling by RAS mutants R-HSA-6802949
MAPK family signaling cascades R-HSA-5683057
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542

Expression Atlas ENSG00000173327
NCBI gene (formerly Entrezgene) 4296
GeneCards 6850
HGNC Symbol HGNC:6850
MIM gene 600050
UniProtKB Gene Name Q16584
WikiGene 4296
Gene: ATP1A3
Ensembl ID : ENSG00000105409
Description: ATPase Na+/K+ transporting subunit alpha 3
Gene Synonyms: DYT12
6 APIs:
134 Possible Orthologues:

Muscle contraction R-HSA-397014
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Cardiac conduction R-HSA-5576891
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Cardiac conduction R-HSA-5576891
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Ion channel transport R-HSA-983712
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Ion channel transport R-HSA-983712
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
Muscle contraction R-HSA-397014
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Ion homeostasis R-HSA-5578775
Transport of small molecules R-HSA-382551
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Ion channel transport R-HSA-983712
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Potential therapeutics for SARS R-HSA-9679191
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685

Expression Atlas ENSG00000105409
LRG display in Ensembl gene LRG_1186
NCBI gene (formerly Entrezgene) 478
GeneCards 801
HGNC Symbol HGNC:801
MIM gene 182350
MIM morbid 619606
UniProtKB Gene Name P13637
WikiGene 478
Gene: GAA
Ensembl ID : ENSG00000171298
Description: alpha glucosidase
Gene Synonyms:
4 APIs:
233 Possible Orthologues:

Glycogen storage diseases R-HSA-3229121
Glycogen storage disease type II (GAA) R-HSA-5357609
Metabolism of carbohydrates R-HSA-71387
Diseases of carbohydrate metabolism R-HSA-5663084
Diseases of metabolism R-HSA-5668914
Glycogen metabolism R-HSA-8982491
Neutrophil degranulation R-HSA-6798695
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Glycogen breakdown (glycogenolysis) R-HSA-70221
Disease R-HSA-1643685
Immune System R-HSA-168256
Glycogen storage disease type II (GAA) R-HSA-5357609
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Neutrophil degranulation R-HSA-6798695
Diseases of carbohydrate metabolism R-HSA-5663084
Metabolism of carbohydrates R-HSA-71387
Glycogen breakdown (glycogenolysis) R-HSA-70221
Glycogen metabolism R-HSA-8982491
Metabolism R-HSA-1430728
Glycogen storage diseases R-HSA-3229121
Innate Immune System R-HSA-168249
Diseases of carbohydrate metabolism R-HSA-5663084
Neutrophil degranulation R-HSA-6798695
Glycogen metabolism R-HSA-8982491
Diseases of metabolism R-HSA-5668914
Metabolism of carbohydrates R-HSA-71387
Glycogen storage diseases R-HSA-3229121
Immune System R-HSA-168256
Disease R-HSA-1643685
Glycogen storage disease type II (GAA) R-HSA-5357609
Innate Immune System R-HSA-168249
Glycogen breakdown (glycogenolysis) R-HSA-70221
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Metabolism of carbohydrates R-HSA-71387
Glycogen storage disease type II (GAA) R-HSA-5357609
Glycogen breakdown (glycogenolysis) R-HSA-70221
Diseases of metabolism R-HSA-5668914
Diseases of carbohydrate metabolism R-HSA-5663084
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Glycogen metabolism R-HSA-8982491
Glycogen storage diseases R-HSA-3229121
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Diseases of carbohydrate metabolism R-HSA-5663084
Glycogen storage diseases R-HSA-3229121
Glycogen metabolism R-HSA-8982491
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Innate Immune System R-HSA-168249
Glycogen storage disease type II (GAA) R-HSA-5357609
Glycogen breakdown (glycogenolysis) R-HSA-70221
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism of carbohydrates R-HSA-71387
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Diseases of carbohydrate metabolism R-HSA-5663084
Glycogen storage diseases R-HSA-3229121
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Glycogen breakdown (glycogenolysis) R-HSA-70221
Glycogen metabolism R-HSA-8982491
Glycogen storage disease type II (GAA) R-HSA-5357609
Diseases of metabolism R-HSA-5668914
Neutrophil degranulation R-HSA-6798695
Glycogen storage diseases R-HSA-3229121
Diseases of carbohydrate metabolism R-HSA-5663084
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Disease R-HSA-1643685
Glycogen metabolism R-HSA-8982491
Immune System R-HSA-168256
Glycogen breakdown (glycogenolysis) R-HSA-70221
Glycogen storage disease type II (GAA) R-HSA-5357609
Innate Immune System R-HSA-168249
Glycogen metabolism R-HSA-8982491
Glycogen breakdown (glycogenolysis) R-HSA-70221
Glycogen storage disease type II (GAA) R-HSA-5357609
Innate Immune System R-HSA-168249
Diseases of carbohydrate metabolism R-HSA-5663084
Metabolism of carbohydrates R-HSA-71387
Immune System R-HSA-168256
Diseases of metabolism R-HSA-5668914
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Glycogen storage diseases R-HSA-3229121
Disease R-HSA-1643685
Glycogen storage disease type II (GAA) R-HSA-5357609
Glycogen storage diseases R-HSA-3229121
Glycogen breakdown (glycogenolysis) R-HSA-70221
Immune System R-HSA-168256
Glycogen metabolism R-HSA-8982491
Innate Immune System R-HSA-168249
Diseases of carbohydrate metabolism R-HSA-5663084
Neutrophil degranulation R-HSA-6798695
Metabolism of carbohydrates R-HSA-71387
Diseases of metabolism R-HSA-5668914
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Glycogen breakdown (glycogenolysis) R-HSA-70221
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Glycogen storage diseases R-HSA-3229121
Glycogen metabolism R-HSA-8982491
Diseases of carbohydrate metabolism R-HSA-5663084
Neutrophil degranulation R-HSA-6798695
Disease R-HSA-1643685
Glycogen storage disease type II (GAA) R-HSA-5357609
Metabolism of carbohydrates R-HSA-71387
Diseases of metabolism R-HSA-5668914

Expression Atlas ENSG00000171298
LRG display in Ensembl gene LRG_673
NCBI gene (formerly Entrezgene) 2548
GeneCards 4065
HGNC Symbol HGNC:4065
MIM gene 606800
MIM morbid 232300
UniProtKB Gene Name P10253
WikiGene 2548
Gene: PSMB7
Ensembl ID : ENSG00000136930
Description: proteasome 20S subunit beta 7
Gene Synonyms: Z
6 APIs:
218 Possible Orthologues:

Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Metabolism of RNA R-HSA-8953854
FCERI mediated NF-kB activation R-HSA-2871837
Neddylation R-HSA-8951664
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1 DNA Damage Response R-HSA-69563
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
RAF/MAP kinase cascade R-HSA-5673001
DNA Replication Pre-Initiation R-HSA-69002
Metabolism of RNA R-HSA-8953854
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 signaling R-HSA-9020702
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by WNT R-HSA-195721
Mitotic G2-G2/M phases R-HSA-453274
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Negative regulation of NOTCH4 signaling R-HSA-9604323
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Ub-specific processing proteases R-HSA-5689880
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Signaling by the B Cell Receptor (BCR) R-HSA-983705
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Regulation of RAS by GAPs R-HSA-5658442
Gene expression (Transcription) R-HSA-74160
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Transport of small molecules R-HSA-382551
Switching of origins to a post-replicative state R-HSA-69052
Regulation of mitotic cell cycle R-HSA-453276
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Synthesis of DNA R-HSA-69239
Apoptosis R-HSA-109581
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Asymmetric localization of PCP proteins R-HSA-4608870
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RUNX2 expression and activity R-HSA-8939902
Intracellular signaling by second messengers R-HSA-9006925
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
ABC-family proteins mediated transport R-HSA-382556
Axon guidance R-HSA-422475
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of PTEN stability and activity R-HSA-8948751
Host Interactions of HIV factors R-HSA-162909
G2/M Checkpoints R-HSA-69481
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
PCP/CE pathway R-HSA-4086400
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ER-Phagosome pathway R-HSA-1236974
Metabolism R-HSA-1430728
Cell Cycle R-HSA-1640170
Hedgehog ligand biogenesis R-HSA-5358346
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
Signaling by NOTCH4 R-HSA-9013694
Adaptive Immune System R-HSA-1280218
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle, Mitotic R-HSA-69278
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
Mitotic Metaphase and Anaphase R-HSA-2555396
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Disease R-HSA-1643685
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
ABC transporter disorders R-HSA-5619084
Degradation of AXIN R-HSA-4641257
Defective CFTR causes cystic fibrosis R-HSA-5678895
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Cell Cycle Checkpoints R-HSA-69620
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Class I MHC mediated antigen processing & presentation R-HSA-983169
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Immune System R-HSA-168256
Signal Transduction R-HSA-162582
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 family signaling R-HSA-446652
Stabilization of p53 R-HSA-69541
Hedgehog 'off' state R-HSA-5610787
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
UCH proteinases R-HSA-5689603
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH4 R-HSA-9013694
Orc1 removal from chromatin R-HSA-68949
Degradation of DVL R-HSA-4641258
Cellular response to hypoxia R-HSA-1234174
Axon guidance R-HSA-422475
Ub-specific processing proteases R-HSA-5689880
Switching of origins to a post-replicative state R-HSA-69052
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Metabolism of polyamines R-HSA-351202
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neutrophil degranulation R-HSA-6798695
Synthesis of DNA R-HSA-69239
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of amino acids and derivatives R-HSA-71291
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Assembly of the pre-replicative complex R-HSA-68867
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Stabilization of p53 R-HSA-69541
Degradation of GLI2 by the proteasome R-HSA-5610783
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Disorders of transmembrane transporters R-HSA-5619115
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog 'off' state R-HSA-5610787
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC transporter disorders R-HSA-5619084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Transport of small molecules R-HSA-382551
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Mitotic Metaphase and Anaphase R-HSA-2555396
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular responses to stimuli R-HSA-8953897
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PCP/CE pathway R-HSA-4086400
Intracellular signaling by second messengers R-HSA-9006925
Separation of Sister Chromatids R-HSA-2467813
Nervous system development R-HSA-9675108
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of AXIN R-HSA-4641257
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Neddylation R-HSA-8951664
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of mitotic cell cycle R-HSA-453276
Mitotic Anaphase R-HSA-68882
Cell Cycle Checkpoints R-HSA-69620
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of beta-catenin by the destruction complex R-HSA-195253
DNA Replication Pre-Initiation R-HSA-69002
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular response to chemical stress R-HSA-9711123
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Beta-catenin independent WNT signaling R-HSA-3858494
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by ROBO receptors R-HSA-376176
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of Apoptosis R-HSA-169911
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
HIV Infection R-HSA-162906
TCR signaling R-HSA-202403
Signaling by NOTCH R-HSA-157118
ER-Phagosome pathway R-HSA-1236974
S Phase R-HSA-69242
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
Signaling by Interleukins R-HSA-449147
Regulation of RUNX3 expression and activity R-HSA-8941858
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Checkpoints R-HSA-69481
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
Cytokine Signaling in Immune system R-HSA-1280215
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants abrogate ligand secretion R-HSA-5387390
PIP3 activates AKT signaling R-HSA-1257604
Defective CFTR causes cystic fibrosis R-HSA-5678895
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Hedgehog 'on' state R-HSA-5632684
MAPK1/MAPK3 signaling R-HSA-5684996
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vif-mediated degradation of APOBEC3G R-HSA-180585
Infectious disease R-HSA-5663205
Cellular responses to stress R-HSA-2262752
Host Interactions of HIV factors R-HSA-162909
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
MAPK6/MAPK4 signaling R-HSA-5687128
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
p53-Independent DNA Damage Response R-HSA-69610
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog 'off' state R-HSA-5610787
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of polyamines R-HSA-351202
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog ligand biogenesis R-HSA-5358346
Infectious disease R-HSA-5663205
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
M Phase R-HSA-68886
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Antigen processing-Cross presentation R-HSA-1236975
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by NOTCH4 R-HSA-9013694
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Class I MHC mediated antigen processing & presentation R-HSA-983169
Adaptive Immune System R-HSA-1280218
Interleukin-1 family signaling R-HSA-446652
Metabolism of amino acids and derivatives R-HSA-71291
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Signaling by Interleukins R-HSA-449147
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by ROBO receptors R-HSA-376176
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1 DNA Damage Response R-HSA-69563
Host Interactions of HIV factors R-HSA-162909
Cellular response to hypoxia R-HSA-1234174
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Anaphase R-HSA-68882
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Synthesis of DNA R-HSA-69239
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
HIV Infection R-HSA-162906
Hedgehog 'on' state R-HSA-5632684
Asymmetric localization of PCP proteins R-HSA-4608870
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX3 expression and activity R-HSA-8941858
Nervous system development R-HSA-9675108
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by Hedgehog R-HSA-5358351
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Beta-catenin independent WNT signaling R-HSA-3858494
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of proteins R-HSA-392499
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RAF/MAP kinase cascade R-HSA-5673001
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Signaling by NOTCH R-HSA-157118
Deubiquitination R-HSA-5688426
FCERI mediated NF-kB activation R-HSA-2871837
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of PTEN stability and activity R-HSA-8948751
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neutrophil degranulation R-HSA-6798695
ABC-family proteins mediated transport R-HSA-382556
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Regulation of Apoptosis R-HSA-169911
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Apoptosis R-HSA-109581
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RAF/MAP kinase cascade R-HSA-5673001
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PTEN Regulation R-HSA-6807070
Signal Transduction R-HSA-162582
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Transition R-HSA-69275
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transcriptional regulation by RUNX1 R-HSA-8878171
G1/S DNA Damage Checkpoints R-HSA-69615
Nuclear events mediated by NFE2L2 R-HSA-9759194
Mitotic G2-G2/M phases R-HSA-453274
MAPK family signaling cascades R-HSA-5683057
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hh mutants abrogate ligand secretion R-HSA-5387390
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Vpu mediated degradation of CD4 R-HSA-180534
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
CLEC7A (Dectin-1) signaling R-HSA-5607764
Axon guidance R-HSA-422475
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
HIV Infection R-HSA-162906
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hh mutants are degraded by ERAD R-HSA-5362768
Cytokine Signaling in Immune system R-HSA-1280215
Activation of NF-kappaB in B cells R-HSA-1169091
PIP3 activates AKT signaling R-HSA-1257604
Nervous system development R-HSA-9675108
Regulation of RAS by GAPs R-HSA-5658442
G2/M Checkpoints R-HSA-69481
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transcriptional regulation by RUNX2 R-HSA-8878166
Cellular response to hypoxia R-HSA-1234174
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin E associated events during G1/S transition R-HSA-69202
UCH proteinases R-HSA-5689603
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PCP/CE pathway R-HSA-4086400
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent DNA Damage Response R-HSA-69610
Synthesis of DNA R-HSA-69239
Metabolism of RNA R-HSA-8953854
p53-Dependent G1 DNA Damage Response R-HSA-69563
Transport of small molecules R-HSA-382551
Orc1 removal from chromatin R-HSA-68949
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of DVL R-HSA-4641258
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Assembly of the pre-replicative complex R-HSA-68867
Degradation of AXIN R-HSA-4641257
Cell Cycle Checkpoints R-HSA-69620
C-type lectin receptors (CLRs) R-HSA-5621481
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle R-HSA-1640170
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by Interleukins R-HSA-449147
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Gene expression (Transcription) R-HSA-74160
Ub-specific processing proteases R-HSA-5689880
Disorders of transmembrane transporters R-HSA-5619115
Host Interactions of HIV factors R-HSA-162909
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
Neddylation R-HSA-8951664
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by ROBO receptors R-HSA-376176
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
TCF dependent signaling in response to WNT R-HSA-201681
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Hh mutants abrogate ligand secretion R-HSA-5387390
PTEN Regulation R-HSA-6807070
Signaling by Hedgehog R-HSA-5358351
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Deubiquitination R-HSA-5688426
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCR signaling R-HSA-202403
Regulation of RUNX2 expression and activity R-HSA-8939902
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Beta-catenin independent WNT signaling R-HSA-3858494
Ub-specific processing proteases R-HSA-5689880
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Switching of origins to a post-replicative state R-HSA-69052
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
NIK-->noncanonical NF-kB signaling R-HSA-5676590
C-type lectin receptors (CLRs) R-HSA-5621481
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Separation of Sister Chromatids R-HSA-2467813
Assembly of the pre-replicative complex R-HSA-68867
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent DNA Damage Response R-HSA-69610
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by NOTCH R-HSA-157118
Hh mutants are degraded by ERAD R-HSA-5362768
Nervous system development R-HSA-9675108
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'off' state R-HSA-5610787
Host Interactions of HIV factors R-HSA-162909
Neutrophil degranulation R-HSA-6798695
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
MAPK6/MAPK4 signaling R-HSA-5687128
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Adaptive Immune System R-HSA-1280218
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Downstream TCR signaling R-HSA-202424
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle, Mitotic R-HSA-69278
ABC-family proteins mediated transport R-HSA-382556
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of Apoptosis R-HSA-169911
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
Transport of small molecules R-HSA-382551
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Immune System R-HSA-168256
Transcriptional regulation by RUNX2 R-HSA-8878166
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog ligand biogenesis R-HSA-5358346
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK family signaling cascades R-HSA-5683057
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication Pre-Initiation R-HSA-69002
Degradation of beta-catenin by the destruction complex R-HSA-195253
Innate Immune System R-HSA-168249
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
Regulation of RUNX3 expression and activity R-HSA-8941858
Post-translational protein modification R-HSA-597592
Cytokine Signaling in Immune system R-HSA-1280215
UCH proteinases R-HSA-5689603
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Signaling by WNT R-HSA-195721
Neddylation R-HSA-8951664
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Metabolism of amino acids and derivatives R-HSA-71291
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism R-HSA-1430728
Interleukin-1 signaling R-HSA-9020702
G2/M Transition R-HSA-69275
G1/S Transition R-HSA-69206
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Negative regulation of NOTCH4 signaling R-HSA-9604323
Gene expression (Transcription) R-HSA-74160
Degradation of GLI2 by the proteasome R-HSA-5610783
PTEN Regulation R-HSA-6807070
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by Hedgehog R-HSA-5358351
Interleukin-1 signaling R-HSA-9020702
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Mitotic Anaphase R-HSA-68882
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
KEAP1-NFE2L2 pathway R-HSA-9755511
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Metabolism of proteins R-HSA-392499
Asymmetric localization of PCP proteins R-HSA-4608870
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH R-HSA-157118
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by WNT R-HSA-195721
Regulation of mitotic cell cycle R-HSA-453276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Switching of origins to a post-replicative state R-HSA-69052
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Disease R-HSA-1643685
Cell Cycle, Mitotic R-HSA-69278
Developmental Biology R-HSA-1266738
Synthesis of DNA R-HSA-69239
PCP/CE pathway R-HSA-4086400
Regulation of RUNX3 expression and activity R-HSA-8941858
G1/S Transition R-HSA-69206
Antigen processing-Cross presentation R-HSA-1236975
Class I MHC mediated antigen processing & presentation R-HSA-983169
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
Programmed Cell Death R-HSA-5357801
ABC transporter disorders R-HSA-5619084
M Phase R-HSA-68886
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Transcriptional regulation by RUNX2 R-HSA-8878166
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Downstream TCR signaling R-HSA-202424
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of Apoptosis R-HSA-169911
Cyclin E associated events during G1/S transition R-HSA-69202
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
Infectious disease R-HSA-5663205
Neutrophil degranulation R-HSA-6798695
Nuclear events mediated by NFE2L2 R-HSA-9759194
Ub-specific processing proteases R-HSA-5689880
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of amino acids and derivatives R-HSA-71291
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transport of small molecules R-HSA-382551
Hedgehog 'off' state R-HSA-5610787
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
C-type lectin receptors (CLRs) R-HSA-5621481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Axon guidance R-HSA-422475
Interleukin-1 family signaling R-HSA-446652
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Adaptive Immune System R-HSA-1280218
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of DVL R-HSA-4641258
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ER-Phagosome pathway R-HSA-1236974
ABC-family proteins mediated transport R-HSA-382556
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic Metaphase and Anaphase R-HSA-2555396
HIV Infection R-HSA-162906
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Activation of NF-kappaB in B cells R-HSA-1169091
G2/M Checkpoints R-HSA-69481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PIP3 activates AKT signaling R-HSA-1257604
Neddylation R-HSA-8951664
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Beta-catenin independent WNT signaling R-HSA-3858494
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
DNA Replication R-HSA-69306
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by WNT R-HSA-195721
MAPK family signaling cascades R-HSA-5683057
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Degradation of DVL R-HSA-4641258
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cell Cycle, Mitotic R-HSA-69278
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RAF/MAP kinase cascade R-HSA-5673001
Cytokine Signaling in Immune system R-HSA-1280215
CLEC7A (Dectin-1) signaling R-HSA-5607764
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Hedgehog 'on' state R-HSA-5632684
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Mitotic Metaphase and Anaphase R-HSA-2555396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Transcriptional regulation by RUNX1 R-HSA-8878171
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Deubiquitination R-HSA-5688426
Developmental Biology R-HSA-1266738
Interleukin-1 family signaling R-HSA-446652
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
TCR signaling R-HSA-202403
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
C-type lectin receptors (CLRs) R-HSA-5621481
G2/M Transition R-HSA-69275
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Synthesis of DNA R-HSA-69239
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Signaling by Interleukins R-HSA-449147
Neddylation R-HSA-8951664
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G1 phase and G1/S transition R-HSA-453279
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Class I MHC mediated antigen processing & presentation R-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Neutrophil degranulation R-HSA-6798695
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Vpu mediated degradation of CD4 R-HSA-180534
Apoptosis R-HSA-109581
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of RNA R-HSA-8953854
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by ROBO receptors R-HSA-376176
Infectious disease R-HSA-5663205
Switching of origins to a post-replicative state R-HSA-69052
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Cell Cycle R-HSA-1640170
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Programmed Cell Death R-HSA-5357801
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RUNX3 expression and activity R-HSA-8941858
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
PCP/CE pathway R-HSA-4086400
G1/S DNA Damage Checkpoints R-HSA-69615
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
MAPK6/MAPK4 signaling R-HSA-5687128
M Phase R-HSA-68886
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Vif-mediated degradation of APOBEC3G R-HSA-180585
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Disorders of transmembrane transporters R-HSA-5619115
Degradation of beta-catenin by the destruction complex R-HSA-195253
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
Antigen processing-Cross presentation R-HSA-1236975
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G2/M Checkpoints R-HSA-69481
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Interleukin-1 family signaling R-HSA-446652
Antigen processing-Cross presentation R-HSA-1236975
Separation of Sister Chromatids R-HSA-2467813
Regulation of mitotic cell cycle R-HSA-453276
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
HIV Infection R-HSA-162906
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
Disease R-HSA-1643685
Regulation of Apoptosis R-HSA-169911
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
PCP/CE pathway R-HSA-4086400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Immune System R-HSA-168256
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Regulation of expression of SLITs and ROBOs R-HSA-9010553
DNA Replication R-HSA-69306
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular response to hypoxia R-HSA-1234174
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
Transcriptional regulation by RUNX3 R-HSA-8878159
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Synthesis of DNA R-HSA-69239
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Class I MHC mediated antigen processing & presentation R-HSA-983169
Mitotic Anaphase R-HSA-68882
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stimuli R-HSA-8953897
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Deubiquitination R-HSA-5688426
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Mitotic Metaphase and Anaphase R-HSA-2555396
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Assembly of the pre-replicative complex R-HSA-68867
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G2-G2/M phases R-HSA-453274
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
Disorders of transmembrane transporters R-HSA-5619115
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
M Phase R-HSA-68886
Cellular response to chemical stress R-HSA-9711123
TCF dependent signaling in response to WNT R-HSA-201681
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Neddylation R-HSA-8951664
Hedgehog 'off' state R-HSA-5610787
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX2 R-HSA-8878166
Vif-mediated degradation of APOBEC3G R-HSA-180585
MAPK6/MAPK4 signaling R-HSA-5687128
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Interleukin-1 signaling R-HSA-9020702
Nervous system development R-HSA-9675108
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
Developmental Biology R-HSA-1266738
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by NOTCH R-HSA-157118
Cell Cycle R-HSA-1640170
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by Interleukins R-HSA-449147
DNA Replication Pre-Initiation R-HSA-69002
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
ER-Phagosome pathway R-HSA-1236974
Cell Cycle, Mitotic R-HSA-69278
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
KEAP1-NFE2L2 pathway R-HSA-9755511
Generic Transcription Pathway R-HSA-212436
Degradation of GLI2 by the proteasome R-HSA-5610783
Post-translational protein modification R-HSA-597592
Downstream TCR signaling R-HSA-202424
Neutrophil degranulation R-HSA-6798695
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by WNT R-HSA-195721
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of RNA R-HSA-8953854
Signaling by NOTCH4 R-HSA-9013694
ABC-family proteins mediated transport R-HSA-382556
Host Interactions of HIV factors R-HSA-162909
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Metabolism of proteins R-HSA-392499
Axon guidance R-HSA-422475
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Degradation of GLI2 by the proteasome R-HSA-5610783
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
DNA Replication R-HSA-69306
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Transition R-HSA-69275
Axon guidance R-HSA-422475
Cell Cycle R-HSA-1640170
Signaling by Hedgehog R-HSA-5358351
Mitotic Anaphase R-HSA-68882
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Downstream TCR signaling R-HSA-202424
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Separation of Sister Chromatids R-HSA-2467813
S Phase R-HSA-69242
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular response to hypoxia R-HSA-1234174
Hh mutants abrogate ligand secretion R-HSA-5387390
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Gene expression (Transcription) R-HSA-74160
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication Pre-Initiation R-HSA-69002
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ub-specific processing proteases R-HSA-5689880
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic G2-G2/M phases R-HSA-453274
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cyclin E associated events during G1/S transition R-HSA-69202
Switching of origins to a post-replicative state R-HSA-69052
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Post-translational protein modification R-HSA-597592
Nervous system development R-HSA-9675108
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signal Transduction R-HSA-162582
Regulation of RAS by GAPs R-HSA-5658442
TCF dependent signaling in response to WNT R-HSA-201681
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 signaling R-HSA-9020702
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX3 R-HSA-8878159
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by ROBO receptors R-HSA-376176
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Infectious disease R-HSA-5663205
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
FCERI mediated NF-kB activation R-HSA-2871837
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
PIP3 activates AKT signaling R-HSA-1257604
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Regulation of Apoptosis R-HSA-169911
Orc1 removal from chromatin R-HSA-68949
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Transport of small molecules R-HSA-382551
Activation of NF-kappaB in B cells R-HSA-1169091
Apoptosis R-HSA-109581
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of GLI1 by the proteasome R-HSA-5610780
M Phase R-HSA-68886
Defective CFTR causes cystic fibrosis R-HSA-5678895
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Vif-mediated degradation of APOBEC3G R-HSA-180585
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Assembly of the pre-replicative complex R-HSA-68867
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by WNT R-HSA-195721
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
MAPK family signaling cascades R-HSA-5683057
Hedgehog 'off' state R-HSA-5610787
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants abrogate ligand secretion R-HSA-5387390
Signaling by the B Cell Receptor (BCR) R-HSA-983705
S Phase R-HSA-69242
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
Regulation of PTEN stability and activity R-HSA-8948751
Vpu mediated degradation of CD4 R-HSA-180534
Generic Transcription Pathway R-HSA-212436
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by Hedgehog R-HSA-5358351
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transcriptional regulation by RUNX3 R-HSA-8878159
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
Gene expression (Transcription) R-HSA-74160
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Apoptosis R-HSA-109581
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
TCF dependent signaling in response to WNT R-HSA-201681
Orc1 removal from chromatin R-HSA-68949
Transport of small molecules R-HSA-382551
Programmed Cell Death R-HSA-5357801
Interleukin-1 signaling R-HSA-9020702
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Signaling by NOTCH4 R-HSA-9013694
Mitotic Metaphase and Anaphase R-HSA-2555396
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
M Phase R-HSA-68886
ABC transporter disorders R-HSA-5619084
Cytokine Signaling in Immune system R-HSA-1280215
FCERI mediated NF-kB activation R-HSA-2871837
Separation of Sister Chromatids R-HSA-2467813
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
Cell Cycle Checkpoints R-HSA-69620
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
Disorders of transmembrane transporters R-HSA-5619115
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neutrophil degranulation R-HSA-6798695
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of DVL R-HSA-4641258
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
Downstream TCR signaling R-HSA-202424
RAF/MAP kinase cascade R-HSA-5673001
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cellular responses to stress R-HSA-2262752
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of polyamines R-HSA-351202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Axon guidance R-HSA-422475
PCP/CE pathway R-HSA-4086400
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
G2/M Checkpoints R-HSA-69481
Regulation of RAS by GAPs R-HSA-5658442
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Disease R-HSA-1643685
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Degradation of GLI2 by the proteasome R-HSA-5610783
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
Intracellular signaling by second messengers R-HSA-9006925
Regulation of Apoptosis R-HSA-169911
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Developmental Biology R-HSA-1266738
G1/S DNA Damage Checkpoints R-HSA-69615
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Mitotic Anaphase R-HSA-68882
C-type lectin receptors (CLRs) R-HSA-5621481
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signal Transduction R-HSA-162582
ER-Phagosome pathway R-HSA-1236974
p53-Independent DNA Damage Response R-HSA-69610
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PTEN Regulation R-HSA-6807070
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Regulation of RUNX2 expression and activity R-HSA-8939902
UCH proteinases R-HSA-5689603
Metabolism of proteins R-HSA-392499
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TCR signaling R-HSA-202403
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by ROBO receptors R-HSA-376176
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cell Cycle, Mitotic R-HSA-69278
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Activation of NF-kappaB in B cells R-HSA-1169091
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX2 R-HSA-8878166

Expression Atlas ENSG00000136930
NCBI gene (formerly Entrezgene) 5695
GeneCards 9544
HGNC Symbol HGNC:9544
MIM gene 604030
UniProtKB Gene Name Q99436
WikiGene 5695
Gene: MAP3K9
Ensembl ID : ENSG00000006432
Description: mitogen-activated protein kinase kinase kinase 9
Gene Synonyms: MEKK9,MLK1,PRKE1
1 APIs:
195 Possible Orthologues:

Expression Atlas ENSG00000006432
NCBI gene (formerly Entrezgene) 4293
GeneCards 6861
HGNC Symbol HGNC:6861
MIM gene 600136
UniProtKB Gene Name P80192
WikiGene 4293
Gene: GUCY1A2
Ensembl ID : ENSG00000152402
Description: guanylate cyclase 1 soluble subunit alpha 2
Gene Synonyms: GC-SA2,GUC1A2
13 APIs:
203 Possible Orthologues:

Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Smooth Muscle Contraction R-HSA-445355
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Muscle contraction R-HSA-397014
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
Smooth Muscle Contraction R-HSA-445355
Smooth Muscle Contraction R-HSA-445355
Muscle contraction R-HSA-397014
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Platelet homeostasis R-HSA-418346
Smooth Muscle Contraction R-HSA-445355
Hemostasis R-HSA-109582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Muscle contraction R-HSA-397014
Platelet homeostasis R-HSA-418346
Smooth Muscle Contraction R-HSA-445355
Smooth Muscle Contraction R-HSA-445355
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
Muscle contraction R-HSA-397014
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Smooth Muscle Contraction R-HSA-445355
Platelet homeostasis R-HSA-418346
Muscle contraction R-HSA-397014
Hemostasis R-HSA-109582
Smooth Muscle Contraction R-HSA-445355
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Smooth Muscle Contraction R-HSA-445355
Hemostasis R-HSA-109582
Smooth Muscle Contraction R-HSA-445355
Platelet homeostasis R-HSA-418346
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154

Expression Atlas ENSG00000152402
NCBI gene (formerly Entrezgene) 2977
GeneCards 4684
HGNC Symbol HGNC:4684
MIM gene 601244
UniProtKB Gene Name P33402
WikiGene 2977
Gene: TEK
Ensembl ID : ENSG00000120156
Description: TEK receptor tyrosine kinase
Gene Synonyms: CD202B,TIE-2,TIE2,VMCM,VMCM1
8 APIs:
166 Possible Orthologues:

Signal Transduction R-HSA-162582
Cell surface interactions at the vascular wall R-HSA-202733
Tie2 Signaling R-HSA-210993
Hemostasis R-HSA-109582
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
Cell surface interactions at the vascular wall R-HSA-202733
MAPK1/MAPK3 signaling R-HSA-5684996
Tie2 Signaling R-HSA-210993
MAPK family signaling cascades R-HSA-5683057
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Tie2 Signaling R-HSA-210993
MAPK family signaling cascades R-HSA-5683057
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
Cell surface interactions at the vascular wall R-HSA-202733
MAPK1/MAPK3 signaling R-HSA-5684996
Cell surface interactions at the vascular wall R-HSA-202733
Tie2 Signaling R-HSA-210993
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
MAPK1/MAPK3 signaling R-HSA-5684996
Cell surface interactions at the vascular wall R-HSA-202733
Hemostasis R-HSA-109582
Tie2 Signaling R-HSA-210993
Cell surface interactions at the vascular wall R-HSA-202733
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
Tie2 Signaling R-HSA-210993
Tie2 Signaling R-HSA-210993
Signal Transduction R-HSA-162582
MAPK family signaling cascades R-HSA-5683057
Cell surface interactions at the vascular wall R-HSA-202733
MAPK1/MAPK3 signaling R-HSA-5684996
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
Hemostasis R-HSA-109582
Tie2 Signaling R-HSA-210993
Cell surface interactions at the vascular wall R-HSA-202733
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Tie2 Signaling R-HSA-210993
MAPK family signaling cascades R-HSA-5683057
MAPK1/MAPK3 signaling R-HSA-5684996
Cell surface interactions at the vascular wall R-HSA-202733
Signal Transduction R-HSA-162582
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Tie2 Signaling R-HSA-210993
Cell surface interactions at the vascular wall R-HSA-202733

Expression Atlas ENSG00000120156
NCBI gene (formerly Entrezgene) 7010
GeneCards 11724
HGNC Symbol HGNC:11724
MIM gene 600221
MIM morbid 617272
UniProtKB Gene Name Q02763
WikiGene 7010