Gene: MAPK1
Ensembl ID : ENSG00000100030
Description: mitogen-activated protein kinase 1
Gene Synonyms: ERK,ERK2,MAPK2,P41MAPK,PRKM1,PRKM2
6 APIs:
214 Possible Orthologues:

Signaling by MAP2K mutants R-HSA-9652169
Hemostasis R-HSA-109582
MAP kinase activation R-HSA-450294
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cytokine Signaling in Immune system R-HSA-1280215
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Infection with Mycobacterium tuberculosis R-HSA-9635486
Ca-dependent events R-HSA-111996
Signaling by MAPK mutants R-HSA-9652817
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR2 signaling R-HSA-5654727
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by Rho GTPases R-HSA-194315
Signaling by TGFB family members R-HSA-9006936
Signaling by FGFR4 R-HSA-5654743
Transcriptional Regulation by NPAS4 R-HSA-9634815
Toll-like Receptor Cascades R-HSA-168898
Signaling by GPCR R-HSA-372790
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Opioid Signalling R-HSA-111885
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Leishmania phagocytosis R-HSA-9664417
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
PLC beta mediated events R-HSA-112043
Signaling by NTRK1 (TRKA) R-HSA-187037
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MAPK1/MAPK3 signaling R-HSA-5684996
Platelet activation, signaling and aggregation R-HSA-76002
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of MAPK pathway R-HSA-5675221
ERK/MAPK targets R-HSA-198753
Intracellular signaling by second messengers R-HSA-9006925
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Insulin receptor R-HSA-74752
Post NMDA receptor activation events R-HSA-438064
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by RAF1 mutants R-HSA-9656223
Suppression of apoptosis R-HSA-9635465
G-protein mediated events R-HSA-112040
Hemostasis R-HSA-109582
RUNX2 regulates bone development R-HSA-8941326
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by MAP2K mutants R-HSA-9652169
MyD88-independent TLR4 cascade R-HSA-166166
phospho-PLA2 pathway R-HSA-111995
Parasite infection R-HSA-9664407
PIP3 activates AKT signaling R-HSA-1257604
MAPK family signaling cascades R-HSA-5683057
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Infectious disease R-HSA-5663205
Mitotic Prophase R-HSA-68875
Negative regulation of FGFR3 signaling R-HSA-5654732
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Growth hormone receptor signaling R-HSA-982772
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
ERKs are inactivated R-HSA-202670
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Neuronal System R-HSA-112316
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of FGFR1 signaling R-HSA-5654726
Neutrophil degranulation R-HSA-6798695
Oncogenic MAPK signaling R-HSA-6802957
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by NODAL R-HSA-1181150
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal transduction by L1 R-HSA-445144
Signaling by ALK in cancer R-HSA-9700206
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RAF-independent MAPK1/3 activation R-HSA-112409
Gene expression (Transcription) R-HSA-74160
Regulation of the apoptosome activity R-HSA-9627069
Signaling by Interleukins R-HSA-449147
Signaling by FGFR2 R-HSA-5654738
Frs2-mediated activation R-HSA-170968
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of HSF1-mediated heat shock response R-HSA-3371453
MyD88 dependent cascade initiated on endosome R-HSA-975155
Prolonged ERK activation events R-HSA-169893
L1CAM interactions R-HSA-373760
Innate Immune System R-HSA-168249
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
G alpha (i) signalling events R-HSA-418594
PTEN Regulation R-HSA-6807070
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Formation of apoptosome R-HSA-111458
ESR-mediated signaling R-HSA-8939211
Insulin receptor signalling cascade R-HSA-74751
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Axon guidance R-HSA-422475
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Regulation of PTEN gene transcription R-HSA-8943724
Oncogene Induced Senescence R-HSA-2559585
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Activin R-HSA-1502540
FCERI mediated MAPK activation R-HSA-2871796
RAF/MAP kinase cascade R-HSA-5673001
Intrinsic Pathway for Apoptosis R-HSA-109606
Transmission across Chemical Synapses R-HSA-112315
Generic Transcription Pathway R-HSA-212436
NCAM signaling for neurite out-growth R-HSA-375165
Signaling downstream of RAS mutants R-HSA-9649948
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by FGFR3 R-HSA-5654741
Signaling by RAS mutants R-HSA-6802949
Apoptosis R-HSA-109581
Immune System R-HSA-168256
Negative feedback regulation of MAPK pathway R-HSA-5674499
Spry regulation of FGF signaling R-HSA-1295596
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by NTRKs R-HSA-166520
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
RHO GTPase Effectors R-HSA-195258
Cellular response to heat stress R-HSA-3371556
Signal attenuation R-HSA-74749
Transcriptional regulation by RUNX2 R-HSA-8878166
Leishmania infection R-HSA-9658195
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by FGFR1 R-HSA-5654736
Programmed Cell Death R-HSA-5357801
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
M Phase R-HSA-68886
G alpha (q) signalling events R-HSA-416476
RSK activation R-HSA-444257
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of the PI3K/AKT network R-HSA-199418
Negative regulation of FGFR4 signaling R-HSA-5654733
Signal Transduction R-HSA-162582
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular Senescence R-HSA-2559583
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cell Cycle, Mitotic R-HSA-69278
FCGR3A-mediated phagocytosis R-HSA-9664422
MAP kinase activation R-HSA-450294
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Response of Mtb to phagocytosis R-HSA-9637690
GPCR downstream signalling R-HSA-388396
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Nuclear Receptors R-HSA-9006931
NPAS4 regulates expression of target genes R-HSA-9768919
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by FGFR R-HSA-190236
MAP2K and MAPK activation R-HSA-5674135
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Apoptotic factor-mediated response R-HSA-111471
Oxidative Stress Induced Senescence R-HSA-2559580
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by NTRK1 (TRKA) R-HSA-187037
phospho-PLA2 pathway R-HSA-111995
Signal Transduction R-HSA-162582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
MyD88 cascade initiated on plasma membrane R-HSA-975871
Transmission across Chemical Synapses R-HSA-112315
Intracellular signaling by second messengers R-HSA-9006925
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
NCAM signaling for neurite out-growth R-HSA-375165
Negative regulation of the PI3K/AKT network R-HSA-199418
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by ALK in cancer R-HSA-9700206
Oncogenic MAPK signaling R-HSA-6802957
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by RAF1 mutants R-HSA-9656223
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G-protein mediated events R-HSA-112040
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Post NMDA receptor activation events R-HSA-438064
Extra-nuclear estrogen signaling R-HSA-9009391
Cellular responses to stimuli R-HSA-8953897
Apoptotic factor-mediated response R-HSA-111471
Ca-dependent events R-HSA-111996
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Mitotic Prophase R-HSA-68875
Axon guidance R-HSA-422475
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MAPK1/MAPK3 signaling R-HSA-5684996
Neutrophil degranulation R-HSA-6798695
Insulin receptor signalling cascade R-HSA-74751
Negative feedback regulation of MAPK pathway R-HSA-5674499
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by Insulin receptor R-HSA-74752
MyD88-independent TLR4 cascade R-HSA-166166
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Transcriptional regulation by RUNX2 R-HSA-8878166
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Hemostasis R-HSA-109582
Response of Mtb to phagocytosis R-HSA-9637690
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Opioid Signalling R-HSA-111885
Infection with Mycobacterium tuberculosis R-HSA-9635486
Leishmania infection R-HSA-9658195
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cellular response to heat stress R-HSA-3371556
Signaling by NTRKs R-HSA-166520
Signaling by Activin R-HSA-1502540
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
FCGR3A-mediated phagocytosis R-HSA-9664422
Apoptosis R-HSA-109581
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by TGFB family members R-HSA-9006936
RUNX2 regulates bone development R-HSA-8941326
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
G alpha (i) signalling events R-HSA-418594
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR4 R-HSA-5654743
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal transduction by L1 R-HSA-445144
GPCR downstream signalling R-HSA-388396
Negative regulation of FGFR4 signaling R-HSA-5654733
Negative regulation of FGFR2 signaling R-HSA-5654727
Infectious disease R-HSA-5663205
MyD88 dependent cascade initiated on endosome R-HSA-975155
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Developmental Biology R-HSA-1266738
Regulation of PTEN gene transcription R-HSA-8943724
ERKs are inactivated R-HSA-202670
Signaling by NODAL R-HSA-1181150
RSK activation R-HSA-444257
Activation of the AP-1 family of transcription factors R-HSA-450341
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Signaling by MAP2K mutants R-HSA-9652169
Prolonged ERK activation events R-HSA-169893
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Regulation of the apoptosome activity R-HSA-9627069
PLC beta mediated events R-HSA-112043
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Leishmania phagocytosis R-HSA-9664417
ERK/MAPK targets R-HSA-198753
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by GPCR R-HSA-372790
G alpha (q) signalling events R-HSA-416476
Signal attenuation R-HSA-74749
Growth hormone receptor signaling R-HSA-982772
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Interleukin-17 signaling R-HSA-448424
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by MAPK mutants R-HSA-9652817
Oncogene Induced Senescence R-HSA-2559585
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Recycling pathway of L1 R-HSA-437239
ESR-mediated signaling R-HSA-8939211
Disease R-HSA-1643685
Parasite infection R-HSA-9664407
Negative regulation of FGFR3 signaling R-HSA-5654732
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by FGFR2 R-HSA-5654738
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PTEN Regulation R-HSA-6807070
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
Innate Immune System R-HSA-168249
RHO GTPase Effectors R-HSA-195258
MAP kinase activation R-HSA-450294
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Frs2-mediated activation R-HSA-170968
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by TGF-beta Receptor Complex R-HSA-170834
Signaling by FGFR1 R-HSA-5654736
Cellular responses to stress R-HSA-2262752
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Cell Cycle, Mitotic R-HSA-69278
FCERI mediated MAPK activation R-HSA-2871796
MAP2K and MAPK activation R-HSA-5674135
Suppression of apoptosis R-HSA-9635465
RAF/MAP kinase cascade R-HSA-5673001
Formation of apoptosome R-HSA-111458
MAPK1 (ERK2) activation R-HSA-112411
Neuronal System R-HSA-112316
Cellular Senescence R-HSA-2559583
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Intrinsic Pathway for Apoptosis R-HSA-109606
Signalling to ERKs R-HSA-187687
Programmed Cell Death R-HSA-5357801
Signaling by RAS mutants R-HSA-6802949
Cell Cycle R-HSA-1640170
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
NPAS4 regulates expression of target genes R-HSA-9768919
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by FGFR R-HSA-190236
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
L1CAM interactions R-HSA-373760
PIP3 activates AKT signaling R-HSA-1257604
Toll-like Receptor Cascades R-HSA-168898
Signaling by FGFR3 R-HSA-5654741
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Oncogenic MAPK signaling R-HSA-6802957
Suppression of apoptosis R-HSA-9635465
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
ESR-mediated signaling R-HSA-8939211
Regulation of the apoptosome activity R-HSA-9627069
Cytokine Signaling in Immune system R-HSA-1280215
ERKs are inactivated R-HSA-202670
PLC beta mediated events R-HSA-112043
Oncogene Induced Senescence R-HSA-2559585
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
GPCR downstream signalling R-HSA-388396
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by RAF1 mutants R-HSA-9656223
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Opioid Signalling R-HSA-111885
Transmission across Chemical Synapses R-HSA-112315
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR2 R-HSA-5654738
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Insulin receptor signalling cascade R-HSA-74751
Prolonged ERK activation events R-HSA-169893
Parasite infection R-HSA-9664407
G alpha (i) signalling events R-HSA-418594
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
RUNX2 regulates bone development R-HSA-8941326
Signaling by GPCR R-HSA-372790
Toll-like Receptor Cascades R-HSA-168898
Transcriptional Regulation by NPAS4 R-HSA-9634815
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
L1CAM interactions R-HSA-373760
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Programmed Cell Death R-HSA-5357801
Frs2-mediated activation R-HSA-170968
Signaling downstream of RAS mutants R-HSA-9649948
FCERI mediated MAPK activation R-HSA-2871796
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by FGFR R-HSA-190236
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Recycling pathway of L1 R-HSA-437239
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Gene expression (Transcription) R-HSA-74160
Signal transduction by L1 R-HSA-445144
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Leishmania infection R-HSA-9658195
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
PTEN Regulation R-HSA-6807070
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Apoptotic factor-mediated response R-HSA-111471
Signal attenuation R-HSA-74749
Response of Mtb to phagocytosis R-HSA-9637690
Signaling by ALK in cancer R-HSA-9700206
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cytochrome c-mediated apoptotic response R-HSA-111461
RAF-independent MAPK1/3 activation R-HSA-112409
Ca-dependent events R-HSA-111996
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Post NMDA receptor activation events R-HSA-438064
Hemostasis R-HSA-109582
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Innate Immune System R-HSA-168249
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR3 R-HSA-5654741
MAP2K and MAPK activation R-HSA-5674135
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Intracellular signaling by second messengers R-HSA-9006925
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Activation of the AP-1 family of transcription factors R-HSA-450341
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by RAS mutants R-HSA-6802949
Regulation of PTEN gene transcription R-HSA-8943724
Platelet activation, signaling and aggregation R-HSA-76002
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
M Phase R-HSA-68886
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR2 signaling R-HSA-5654727
Disease R-HSA-1643685
MAP kinase activation R-HSA-450294
Mitotic Prophase R-HSA-68875
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Apoptosis R-HSA-109581
Signaling by Activin R-HSA-1502540
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (q) signalling events R-HSA-416476
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
G-protein mediated events R-HSA-112040
FCGR3A-mediated phagocytosis R-HSA-9664422
MyD88 cascade initiated on plasma membrane R-HSA-975871
Developmental Biology R-HSA-1266738
Growth hormone receptor signaling R-HSA-982772
Neuronal System R-HSA-112316
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Axon guidance R-HSA-422475
Infection with Mycobacterium tuberculosis R-HSA-9635486
Extra-nuclear estrogen signaling R-HSA-9009391
Signalling to ERKs R-HSA-187687
RHO GTPase Effectors R-HSA-195258
Cell Cycle, Mitotic R-HSA-69278
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Neutrophil degranulation R-HSA-6798695
RNA Polymerase II Transcription R-HSA-73857
Signaling by Insulin receptor R-HSA-74752
Negative regulation of FGFR4 signaling R-HSA-5654733
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Negative feedback regulation of MAPK pathway R-HSA-5674499
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
phospho-PLA2 pathway R-HSA-111995
Signaling by Nuclear Receptors R-HSA-9006931
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Spry regulation of FGF signaling R-HSA-1295596
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by NODAL R-HSA-1181150
Cellular responses to stimuli R-HSA-8953897
MAPK1 (ERK2) activation R-HSA-112411
Signaling by TGFB family members R-HSA-9006936
RSK activation R-HSA-444257
Cellular response to heat stress R-HSA-3371556
Cellular responses to stress R-HSA-2262752
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by TGF-beta Receptor Complex R-HSA-170834
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ERK/MAPK targets R-HSA-198753
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR4 R-HSA-5654743
Signaling by MAPK mutants R-HSA-9652817
Signaling by FGFR1 R-HSA-5654736
Leishmania phagocytosis R-HSA-9664417
NCAM signaling for neurite out-growth R-HSA-375165
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Negative regulation of FGFR3 signaling R-HSA-5654732
Nervous system development R-HSA-9675108
Interleukin-17 signaling R-HSA-448424
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Negative regulation of MAPK pathway R-HSA-5675221
Advanced glycosylation endproduct receptor signaling R-HSA-879415
RSK activation R-HSA-444257
G alpha (i) signalling events R-HSA-418594
Cellular responses to stimuli R-HSA-8953897
RUNX2 regulates bone development R-HSA-8941326
Developmental Biology R-HSA-1266738
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Regulation of PTEN gene transcription R-HSA-8943724
ERK/MAPK targets R-HSA-198753
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Oncogenic MAPK signaling R-HSA-6802957
Platelet activation, signaling and aggregation R-HSA-76002
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Apoptosis R-HSA-109581
Negative regulation of FGFR3 signaling R-HSA-5654732
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Nuclear Receptors R-HSA-9006931
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR4 R-HSA-5654743
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Growth hormone receptor signaling R-HSA-982772
Signaling by ALK in cancer R-HSA-9700206
Negative regulation of MAPK pathway R-HSA-5675221
phospho-PLA2 pathway R-HSA-111995
Oncogene Induced Senescence R-HSA-2559585
Negative feedback regulation of MAPK pathway R-HSA-5674499
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cell Cycle R-HSA-1640170
MAP2K and MAPK activation R-HSA-5674135
Neuronal System R-HSA-112316
MyD88 dependent cascade initiated on endosome R-HSA-975155
Recycling pathway of L1 R-HSA-437239
Signaling by FGFR3 R-HSA-5654741
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Axon guidance R-HSA-422475
Insulin receptor signalling cascade R-HSA-74751
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases R-HSA-194315
Cell Cycle, Mitotic R-HSA-69278
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cytochrome c-mediated apoptotic response R-HSA-111461
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by RAS mutants R-HSA-6802949
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Negative regulation of FGFR4 signaling R-HSA-5654733
ERKs are inactivated R-HSA-202670
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Infectious disease R-HSA-5663205
Signaling by FGFR R-HSA-190236
Cellular Senescence R-HSA-2559583
FCGR3A-mediated phagocytosis R-HSA-9664422
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
ESR-mediated signaling R-HSA-8939211
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
MAP kinase activation R-HSA-450294
Transcriptional regulation by RUNX2 R-HSA-8878166
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling downstream of RAS mutants R-HSA-9649948
Programmed Cell Death R-HSA-5357801
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Gene expression (Transcription) R-HSA-74160
Spry regulation of FGF signaling R-HSA-1295596
Signaling by Interleukins R-HSA-449147
MyD88 cascade initiated on plasma membrane R-HSA-975871
Post NMDA receptor activation events R-HSA-438064
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
GPCR downstream signalling R-HSA-388396
Parasite infection R-HSA-9664407
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
L1CAM interactions R-HSA-373760
Signaling by FGFR2 R-HSA-5654738
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by NTRK1 (TRKA) R-HSA-187037
Transmission across Chemical Synapses R-HSA-112315
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Opioid Signalling R-HSA-111885
Mitotic Prophase R-HSA-68875
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Toll-like Receptor Cascades R-HSA-168898
Signal Transduction R-HSA-162582
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by RAF1 mutants R-HSA-9656223
Apoptotic factor-mediated response R-HSA-111471
Signaling by TGFB family members R-HSA-9006936
Regulation of the apoptosome activity R-HSA-9627069
Leishmania phagocytosis R-HSA-9664417
Signaling by MAP2K mutants R-HSA-9652169
MAPK family signaling cascades R-HSA-5683057
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
RNA Polymerase II Transcription R-HSA-73857
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by FGFR1 R-HSA-5654736
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Frs2-mediated activation R-HSA-170968
NPAS4 regulates expression of target genes R-HSA-9768919
Infection with Mycobacterium tuberculosis R-HSA-9635486
Formation of apoptosome R-HSA-111458
Ca-dependent events R-HSA-111996
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
M Phase R-HSA-68886
PLC beta mediated events R-HSA-112043
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Advanced glycosylation endproduct receptor signaling R-HSA-879415
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Transcriptional Regulation by NPAS4 R-HSA-9634815
PTEN Regulation R-HSA-6807070
G alpha (q) signalling events R-HSA-416476
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Cellular response to heat stress R-HSA-3371556
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Suppression of apoptosis R-HSA-9635465
Signaling by MAPK mutants R-HSA-9652817
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by GPCR R-HSA-372790
Signaling by Insulin receptor R-HSA-74752
Leishmania infection R-HSA-9658195
Signal transduction by L1 R-HSA-445144
PIP3 activates AKT signaling R-HSA-1257604
Intracellular signaling by second messengers R-HSA-9006925
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR2 signaling R-HSA-5654727
G-protein mediated events R-HSA-112040
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by NTRKs R-HSA-166520
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by Activin R-HSA-1502540
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal attenuation R-HSA-74749
Signalling to ERKs R-HSA-187687
Signaling by TGF-beta Receptor Complex R-HSA-170834
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of FGFR1 signaling R-HSA-5654726
FCERI mediated MAPK activation R-HSA-2871796
MAPK1/MAPK3 signaling R-HSA-5684996
Response of Mtb to phagocytosis R-HSA-9637690
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
PIP3 activates AKT signaling R-HSA-1257604
Cytochrome c-mediated apoptotic response R-HSA-111461
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by GPCR R-HSA-372790
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RUNX2 regulates bone development R-HSA-8941326
Signaling by MAP2K mutants R-HSA-9652169
RAF/MAP kinase cascade R-HSA-5673001
Cell Cycle, Mitotic R-HSA-69278
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by TGF-beta Receptor Complex R-HSA-170834
Apoptosis R-HSA-109581
Gene expression (Transcription) R-HSA-74160
Transmission across Chemical Synapses R-HSA-112315
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Ca-dependent events R-HSA-111996
Suppression of apoptosis R-HSA-9635465
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Oxidative Stress Induced Senescence R-HSA-2559580
Neuronal System R-HSA-112316
Cellular response to heat stress R-HSA-3371556
Platelet activation, signaling and aggregation R-HSA-76002
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Negative regulation of MAPK pathway R-HSA-5675221
Formation of apoptosome R-HSA-111458
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by NTRKs R-HSA-166520
Signaling by RAS mutants R-HSA-6802949
MAP kinase activation R-HSA-450294
Signaling by ALK fusions and activated point mutants R-HSA-9725370
MAPK1/MAPK3 signaling R-HSA-5684996
RSK activation R-HSA-444257
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Programmed Cell Death R-HSA-5357801
Signal attenuation R-HSA-74749
Infection with Mycobacterium tuberculosis R-HSA-9635486
Neutrophil degranulation R-HSA-6798695
Signaling by FGFR3 R-HSA-5654741
Prolonged ERK activation events R-HSA-169893
Growth hormone receptor signaling R-HSA-982772
G-protein mediated events R-HSA-112040
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Generic Transcription Pathway R-HSA-212436
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR3 signaling R-HSA-5654732
MAPK1 (ERK2) activation R-HSA-112411
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of the apoptosome activity R-HSA-9627069
Insulin receptor signalling cascade R-HSA-74751
Signaling by FGFR4 R-HSA-5654743
MAPK family signaling cascades R-HSA-5683057
Signaling by RAF1 mutants R-HSA-9656223
Signaling downstream of RAS mutants R-HSA-9649948
Leishmania phagocytosis R-HSA-9664417
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
M Phase R-HSA-68886
Oncogenic MAPK signaling R-HSA-6802957
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by Rho GTPases R-HSA-194315
Extra-nuclear estrogen signaling R-HSA-9009391
MyD88-independent TLR4 cascade R-HSA-166166
Oncogene Induced Senescence R-HSA-2559585
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signal transduction by L1 R-HSA-445144
Leishmania infection R-HSA-9658195
Frs2-mediated activation R-HSA-170968
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
G alpha (i) signalling events R-HSA-418594
Signal Transduction R-HSA-162582
PLC beta mediated events R-HSA-112043
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
ERK/MAPK targets R-HSA-198753
Signaling by Activin R-HSA-1502540
MAP2K and MAPK activation R-HSA-5674135
Nervous system development R-HSA-9675108
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of the PI3K/AKT network R-HSA-199418
RAF-independent MAPK1/3 activation R-HSA-112409
FCERI mediated MAPK activation R-HSA-2871796
Innate Immune System R-HSA-168249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-17 signaling R-HSA-448424
Disease R-HSA-1643685
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by FGFR2 R-HSA-5654738
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Infectious disease R-HSA-5663205
phospho-PLA2 pathway R-HSA-111995
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by NPAS4 R-HSA-9634815
Mitotic Prophase R-HSA-68875
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Recycling pathway of L1 R-HSA-437239
Cellular Senescence R-HSA-2559583
Signaling by NTRK1 (TRKA) R-HSA-187037
Intrinsic Pathway for Apoptosis R-HSA-109606
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
RHO GTPase Effectors R-HSA-195258
PTEN Regulation R-HSA-6807070
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signalling to ERKs R-HSA-187687
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MyD88 cascade initiated on plasma membrane R-HSA-975871
G alpha (q) signalling events R-HSA-416476
Signaling by FGFR R-HSA-190236
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by Insulin receptor R-HSA-74752
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Hemostasis R-HSA-109582
Signaling by MAPK mutants R-HSA-9652817
ESR-mediated signaling R-HSA-8939211
Post NMDA receptor activation events R-HSA-438064
Cell Cycle R-HSA-1640170
Parasite infection R-HSA-9664407
Signaling by FGFR1 R-HSA-5654736
Opioid Signalling R-HSA-111885
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR2 signaling R-HSA-5654727
Apoptotic factor-mediated response R-HSA-111471
Signaling by ALK in cancer R-HSA-9700206
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by TGFB family members R-HSA-9006936
Immune System R-HSA-168256
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
L1CAM interactions R-HSA-373760
GPCR downstream signalling R-HSA-388396
Transcriptional regulation by RUNX2 R-HSA-8878166
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Cellular responses to stimuli R-HSA-8953897
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by Interleukins R-HSA-449147
Response of Mtb to phagocytosis R-HSA-9637690
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
ERKs are inactivated R-HSA-202670
RUNX2 regulates osteoblast differentiation R-HSA-8940973
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Intracellular signaling by second messengers R-HSA-9006925
MyD88 cascade initiated on plasma membrane R-HSA-975871
Leishmania infection R-HSA-9658195
Prolonged ERK activation events R-HSA-169893
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
phospho-PLA2 pathway R-HSA-111995
Programmed Cell Death R-HSA-5357801
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Interleukins R-HSA-449147
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signalling to ERKs R-HSA-187687
Signaling by MAP2K mutants R-HSA-9652169
Signaling by GPCR R-HSA-372790
Signal attenuation R-HSA-74749
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ERKs are inactivated R-HSA-202670
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cytochrome c-mediated apoptotic response R-HSA-111461
GPCR downstream signalling R-HSA-388396
FCERI mediated MAPK activation R-HSA-2871796
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by FGFR1 R-HSA-5654736
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Negative regulation of MAPK pathway R-HSA-5675221
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MAPK1/MAPK3 signaling R-HSA-5684996
Suppression of apoptosis R-HSA-9635465
Cellular response to heat stress R-HSA-3371556
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Negative regulation of FGFR1 signaling R-HSA-5654726
MAP2K and MAPK activation R-HSA-5674135
Immune System R-HSA-168256
Interleukin-17 signaling R-HSA-448424
Signaling by RAF1 mutants R-HSA-9656223
MAPK1 (ERK2) activation R-HSA-112411
Signaling by BRAF and RAF1 fusions R-HSA-6802952
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by TGF-beta Receptor Complex R-HSA-170834
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Infection with Mycobacterium tuberculosis R-HSA-9635486
Toll-like Receptor Cascades R-HSA-168898
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Axon guidance R-HSA-422475
Neutrophil degranulation R-HSA-6798695
Leishmania phagocytosis R-HSA-9664417
PTEN Regulation R-HSA-6807070
Regulation of PTEN gene transcription R-HSA-8943724
Post NMDA receptor activation events R-HSA-438064
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by TGFB family members R-HSA-9006936
Signaling by MAPK mutants R-HSA-9652817
Apoptotic factor-mediated response R-HSA-111471
Frs2-mediated activation R-HSA-170968
Signaling by Rho GTPases R-HSA-194315
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Transmission across Chemical Synapses R-HSA-112315
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Negative regulation of the PI3K/AKT network R-HSA-199418
Generic Transcription Pathway R-HSA-212436
Neuronal System R-HSA-112316
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal transduction by L1 R-HSA-445144
RSK activation R-HSA-444257
NCAM signaling for neurite out-growth R-HSA-375165
Ca-dependent events R-HSA-111996
Signaling by FGFR R-HSA-190236
Disease R-HSA-1643685
ESR-mediated signaling R-HSA-8939211
Formation of apoptosome R-HSA-111458
NPAS4 regulates expression of target genes R-HSA-9768919
Oncogenic MAPK signaling R-HSA-6802957
Oncogene Induced Senescence R-HSA-2559585
ERK/MAPK targets R-HSA-198753
Signaling by FGFR4 R-HSA-5654743
Opioid Signalling R-HSA-111885
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by FGFR3 R-HSA-5654741
MyD88-independent TLR4 cascade R-HSA-166166
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cellular responses to stress R-HSA-2262752
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Signaling by RAS mutants R-HSA-6802949
Intrinsic Pathway for Apoptosis R-HSA-109606
G-protein mediated events R-HSA-112040
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
PLC beta mediated events R-HSA-112043
Signaling by NTRKs R-HSA-166520
Growth hormone receptor signaling R-HSA-982772
Parasite infection R-HSA-9664407
Signaling by NTRK1 (TRKA) R-HSA-187037
Developmental Biology R-HSA-1266738
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
M Phase R-HSA-68886
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NODAL R-HSA-1181150
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Signaling by Nuclear Receptors R-HSA-9006931
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Cellular Senescence R-HSA-2559583
Extra-nuclear estrogen signaling R-HSA-9009391
Signaling by FGFR2 R-HSA-5654738
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of FGFR2 signaling R-HSA-5654727
Infectious disease R-HSA-5663205
Spry regulation of FGF signaling R-HSA-1295596
Mitotic Prophase R-HSA-68875
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Signaling by Activin R-HSA-1502540
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of HSF1-mediated heat shock response R-HSA-3371453
G alpha (q) signalling events R-HSA-416476
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
RAF-independent MAPK1/3 activation R-HSA-112409
MyD88 dependent cascade initiated on endosome R-HSA-975155
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cell Cycle R-HSA-1640170
Regulation of the apoptosome activity R-HSA-9627069
RNA Polymerase II Transcription R-HSA-73857
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
L1CAM interactions R-HSA-373760
Activation of the AP-1 family of transcription factors R-HSA-450341
G alpha (i) signalling events R-HSA-418594
Insulin receptor signalling cascade R-HSA-74751
Response of Mtb to phagocytosis R-HSA-9637690
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Apoptosis R-HSA-109581
Signaling by Insulin receptor R-HSA-74752
Signaling by ALK in cancer R-HSA-9700206
Transcriptional regulation by RUNX2 R-HSA-8878166
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RUNX2 regulates bone development R-HSA-8941326
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Opioid Signalling R-HSA-111885
Signaling by RAF1 mutants R-HSA-9656223
Transmission across Chemical Synapses R-HSA-112315
MAP2K and MAPK activation R-HSA-5674135
Axon guidance R-HSA-422475
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
G alpha (q) signalling events R-HSA-416476
FCGR3A-mediated phagocytosis R-HSA-9664422
RAF/MAP kinase cascade R-HSA-5673001
Insulin receptor signalling cascade R-HSA-74751
Cellular responses to stress R-HSA-2262752
Signaling by FGFR2 R-HSA-5654738
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Negative regulation of FGFR4 signaling R-HSA-5654733
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Growth hormone receptor signaling R-HSA-982772
M Phase R-HSA-68886
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Spry regulation of FGF signaling R-HSA-1295596
Signaling by RAS mutants R-HSA-6802949
MAPK1/MAPK3 signaling R-HSA-5684996
MyD88-independent TLR4 cascade R-HSA-166166
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Frs2-mediated activation R-HSA-170968
Cellular Senescence R-HSA-2559583
Interleukin-17 signaling R-HSA-448424
Prolonged ERK activation events R-HSA-169893
Negative regulation of MAPK pathway R-HSA-5675221
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of PTEN gene transcription R-HSA-8943724
Transcriptional regulation by RUNX2 R-HSA-8878166
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NODAL R-HSA-1181150
Negative regulation of FGFR1 signaling R-HSA-5654726
Immune System R-HSA-168256
Recycling pathway of L1 R-HSA-437239
Developmental Biology R-HSA-1266738
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
phospho-PLA2 pathway R-HSA-111995
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Neutrophil degranulation R-HSA-6798695
MAP kinase activation R-HSA-450294
Infection with Mycobacterium tuberculosis R-HSA-9635486
Signaling by Rho GTPases R-HSA-194315
Intracellular signaling by second messengers R-HSA-9006925
RUNX2 regulates bone development R-HSA-8941326
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Nuclear Receptors R-HSA-9006931
Generic Transcription Pathway R-HSA-212436
Signal attenuation R-HSA-74749
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by NTRK1 (TRKA) R-HSA-187037
Parasite infection R-HSA-9664407
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FGFR R-HSA-190236
Oxidative Stress Induced Senescence R-HSA-2559580
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
G-protein mediated events R-HSA-112040
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RAF-independent MAPK1/3 activation R-HSA-112409
L1CAM interactions R-HSA-373760
Response of Mtb to phagocytosis R-HSA-9637690
Activation of NMDA receptors and postsynaptic events R-HSA-442755
GPCR downstream signalling R-HSA-388396
Regulation of HSF1-mediated heat shock response R-HSA-3371453
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by Interleukins R-HSA-449147
Signalling to ERKs R-HSA-187687
Signaling by MAPK mutants R-HSA-9652817
MAPK family signaling cascades R-HSA-5683057
RNA Polymerase II Transcription R-HSA-73857
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Hemostasis R-HSA-109582
Signaling by GPCR R-HSA-372790
ERKs are inactivated R-HSA-202670
Mitotic Prophase R-HSA-68875
Suppression of apoptosis R-HSA-9635465
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 cascade initiated on plasma membrane R-HSA-975871
Disease R-HSA-1643685
Oncogenic MAPK signaling R-HSA-6802957
Regulation of the apoptosome activity R-HSA-9627069
Infectious disease R-HSA-5663205
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Negative regulation of FGFR2 signaling R-HSA-5654727
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Cytochrome c-mediated apoptotic response R-HSA-111461
Formation of apoptosome R-HSA-111458
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Signaling by ALK in cancer R-HSA-9700206
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Ca-dependent events R-HSA-111996
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Leishmania phagocytosis R-HSA-9664417
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PIP3 activates AKT signaling R-HSA-1257604
ERK/MAPK targets R-HSA-198753
Signaling by TGFB family members R-HSA-9006936
PLC beta mediated events R-HSA-112043
Nervous system development R-HSA-9675108
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signaling by NTRKs R-HSA-166520
Signaling by TGF-beta Receptor Complex R-HSA-170834
Apoptotic factor-mediated response R-HSA-111471
Oncogene Induced Senescence R-HSA-2559585
Signal transduction by L1 R-HSA-445144
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by FGFR3 R-HSA-5654741
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
MyD88 dependent cascade initiated on endosome R-HSA-975155
Negative feedback regulation of MAPK pathway R-HSA-5674499
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RHO GTPase Effectors R-HSA-195258
FCERI mediated MAPK activation R-HSA-2871796
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Activin R-HSA-1502540
Signaling by MAP2K mutants R-HSA-9652169
Post NMDA receptor activation events R-HSA-438064
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Cellular response to heat stress R-HSA-3371556
RSK activation R-HSA-444257
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Leishmania infection R-HSA-9658195
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signaling by Insulin receptor R-HSA-74752
Activation of the AP-1 family of transcription factors R-HSA-450341
Platelet activation, signaling and aggregation R-HSA-76002
Cell Cycle R-HSA-1640170
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Apoptosis R-HSA-109581
G alpha (i) signalling events R-HSA-418594
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
ESR-mediated signaling R-HSA-8939211
Extra-nuclear estrogen signaling R-HSA-9009391
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
PTEN Regulation R-HSA-6807070
NPAS4 regulates expression of target genes R-HSA-9768919
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling downstream of RAS mutants R-HSA-9649948
MAPK1 (ERK2) activation R-HSA-112411
Signaling by FGFR4 R-HSA-5654743
Neuronal System R-HSA-112316
Regulation of the apoptosome activity R-HSA-9627069
Signaling by FGFR4 R-HSA-5654743
Oncogenic MAPK signaling R-HSA-6802957
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal transduction by L1 R-HSA-445144
Negative regulation of FGFR4 signaling R-HSA-5654733
G alpha (i) signalling events R-HSA-418594
Infectious disease R-HSA-5663205
Transmission across Chemical Synapses R-HSA-112315
Activation of the AP-1 family of transcription factors R-HSA-450341
PIP3 activates AKT signaling R-HSA-1257604
Signaling by RAS mutants R-HSA-6802949
Post NMDA receptor activation events R-HSA-438064
PTEN Regulation R-HSA-6807070
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
M Phase R-HSA-68886
Infection with Mycobacterium tuberculosis R-HSA-9635486
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Leishmania phagocytosis R-HSA-9664417
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by FGFR1 R-HSA-5654736
Signaling by BRAF and RAF1 fusions R-HSA-6802952
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Insulin receptor R-HSA-74752
MAPK1 (ERK2) activation R-HSA-112411
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Activin R-HSA-1502540
MAP kinase activation R-HSA-450294
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Cell Cycle, Mitotic R-HSA-69278
Signaling by TGFB family members R-HSA-9006936
ERKs are inactivated R-HSA-202670
Recycling pathway of L1 R-HSA-437239
G-protein mediated events R-HSA-112040
Intracellular signaling by second messengers R-HSA-9006925
Extra-nuclear estrogen signaling R-HSA-9009391
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
RSK activation R-HSA-444257
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
L1CAM interactions R-HSA-373760
Transcriptional Regulation by NPAS4 R-HSA-9634815
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Regulation of PTEN gene transcription R-HSA-8943724
Ca-dependent events R-HSA-111996
Hemostasis R-HSA-109582
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of HSF1-mediated heat shock response R-HSA-3371453
GPCR downstream signalling R-HSA-388396
Axon guidance R-HSA-422475
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Innate Immune System R-HSA-168249
Cellular Senescence R-HSA-2559583
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by MAP2K mutants R-HSA-9652169
Signaling by NODAL R-HSA-1181150
Signaling by NTRKs R-HSA-166520
Apoptotic factor-mediated response R-HSA-111471
Cellular responses to stimuli R-HSA-8953897
Signaling by FGFR R-HSA-190236
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
Neuronal System R-HSA-112316
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Negative regulation of FGFR3 signaling R-HSA-5654732
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Mitotic Prophase R-HSA-68875
Formation of apoptosome R-HSA-111458
Programmed Cell Death R-HSA-5357801
NCAM signaling for neurite out-growth R-HSA-375165
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Apoptosis R-HSA-109581
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by RAF1 mutants R-HSA-9656223
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Growth hormone receptor signaling R-HSA-982772
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
FCGR3A-mediated phagocytosis R-HSA-9664422
Platelet activation, signaling and aggregation R-HSA-76002
MAPK family signaling cascades R-HSA-5683057
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by GPCR R-HSA-372790
ERK/MAPK targets R-HSA-198753
RUNX2 regulates bone development R-HSA-8941326
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by Interleukins R-HSA-449147
Negative regulation of FGFR1 signaling R-HSA-5654726
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Opioid Signalling R-HSA-111885
Signal attenuation R-HSA-74749
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
RHO GTPase Effectors R-HSA-195258
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Immune System R-HSA-168256
FCERI mediated MAPK activation R-HSA-2871796
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
MyD88 dependent cascade initiated on endosome R-HSA-975155
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by FGFR3 R-HSA-5654741
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
ESR-mediated signaling R-HSA-8939211
Parasite infection R-HSA-9664407
phospho-PLA2 pathway R-HSA-111995
Signalling to ERKs R-HSA-187687
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling downstream of RAS mutants R-HSA-9649948
NPAS4 regulates expression of target genes R-HSA-9768919
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Generic Transcription Pathway R-HSA-212436
Frs2-mediated activation R-HSA-170968
Leishmania infection R-HSA-9658195
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
MyD88-independent TLR4 cascade R-HSA-166166
RAF/MAP kinase cascade R-HSA-5673001
Oxidative Stress Induced Senescence R-HSA-2559580
Negative regulation of FGFR2 signaling R-HSA-5654727
Nervous system development R-HSA-9675108
MyD88 cascade initiated on plasma membrane R-HSA-975871
Oncogene Induced Senescence R-HSA-2559585
Prolonged ERK activation events R-HSA-169893
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Cellular response to heat stress R-HSA-3371556
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Negative regulation of MAPK pathway R-HSA-5675221
PLC beta mediated events R-HSA-112043
Signaling by ALK in cancer R-HSA-9700206
Toll-like Receptor Cascades R-HSA-168898
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR2 R-HSA-5654738
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAP2K and MAPK activation R-HSA-5674135
Signaling by MAPK mutants R-HSA-9652817
Response of Mtb to phagocytosis R-HSA-9637690
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RNA Polymerase II Transcription R-HSA-73857
Interleukin-17 signaling R-HSA-448424
Cell Cycle R-HSA-1640170
Suppression of apoptosis R-HSA-9635465
RAF-independent MAPK1/3 activation R-HSA-112409
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G alpha (q) signalling events R-HSA-416476
Cytochrome c-mediated apoptotic response R-HSA-111461
Signaling by TGF-beta Receptor Complex R-HSA-170834
Insulin receptor signalling cascade R-HSA-74751
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR3 R-HSA-5654741
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
PLC beta mediated events R-HSA-112043
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Opioid Signalling R-HSA-111885
Infection with Mycobacterium tuberculosis R-HSA-9635486
RAF-independent MAPK1/3 activation R-HSA-112409
Cell Cycle, Mitotic R-HSA-69278
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by MAPK mutants R-HSA-9652817
G alpha (q) signalling events R-HSA-416476
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
NPAS4 regulates expression of target genes R-HSA-9768919
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Post NMDA receptor activation events R-HSA-438064
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Oncogene Induced Senescence R-HSA-2559585
Signaling by Interleukins R-HSA-449147
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by GPCR R-HSA-372790
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Response of Mtb to phagocytosis R-HSA-9637690
ERKs are inactivated R-HSA-202670
Ca-dependent events R-HSA-111996
MyD88-independent TLR4 cascade R-HSA-166166
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Signal Transduction R-HSA-162582
NCAM signaling for neurite out-growth R-HSA-375165
Activation of the AP-1 family of transcription factors R-HSA-450341
Regulation of the apoptosome activity R-HSA-9627069
Signaling by Insulin receptor R-HSA-74752
Formation of apoptosome R-HSA-111458
Cellular Senescence R-HSA-2559583
Advanced glycosylation endproduct receptor signaling R-HSA-879415
G-protein mediated events R-HSA-112040
ERK/MAPK targets R-HSA-198753
Innate Immune System R-HSA-168249
Cell Cycle R-HSA-1640170
Growth hormone receptor signaling R-HSA-982772
Signaling by FGFR1 R-HSA-5654736
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Rho GTPases R-HSA-194315
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by RAS mutants R-HSA-6802949
RNA Polymerase II Transcription R-HSA-73857
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
FCERI mediated MAPK activation R-HSA-2871796
RAF/MAP kinase cascade R-HSA-5673001
Signaling by MAP2K mutants R-HSA-9652169
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Oncogenic MAPK signaling R-HSA-6802957
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
FCGR3A-mediated phagocytosis R-HSA-9664422
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by RAF1 mutants R-HSA-9656223
Signaling by FGFR4 R-HSA-5654743
Leishmania infection R-HSA-9658195
Spry regulation of FGF signaling R-HSA-1295596
Generic Transcription Pathway R-HSA-212436
Recycling pathway of L1 R-HSA-437239
Interleukin-17 signaling R-HSA-448424
ESR-mediated signaling R-HSA-8939211
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Negative regulation of the PI3K/AKT network R-HSA-199418
Regulation of PTEN gene transcription R-HSA-8943724
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Cellular response to heat stress R-HSA-3371556
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll-like Receptor Cascades R-HSA-168898
Apoptotic factor-mediated response R-HSA-111471
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Infectious disease R-HSA-5663205
Signaling by Activin R-HSA-1502540
MAPK family signaling cascades R-HSA-5683057
Signaling by ALK in cancer R-HSA-9700206
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of MAPK pathway R-HSA-5675221
Frs2-mediated activation R-HSA-170968
RSK activation R-HSA-444257
Intracellular signaling by second messengers R-HSA-9006925
Programmed Cell Death R-HSA-5357801
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Apoptosis R-HSA-109581
Signalling to ERKs R-HSA-187687
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
L1CAM interactions R-HSA-373760
Parasite infection R-HSA-9664407
Prolonged ERK activation events R-HSA-169893
Extra-nuclear estrogen signaling R-HSA-9009391
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Signaling by FGFR2 R-HSA-5654738
Platelet activation, signaling and aggregation R-HSA-76002
Axon guidance R-HSA-422475
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Oxidative Stress Induced Senescence R-HSA-2559580
Suppression of apoptosis R-HSA-9635465
Signaling by NODAL R-HSA-1181150
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Signaling by Nuclear Receptors R-HSA-9006931
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Leishmania phagocytosis R-HSA-9664417
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
PTEN Regulation R-HSA-6807070
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cellular responses to stress R-HSA-2262752
Signal transduction by L1 R-HSA-445144
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
GPCR downstream signalling R-HSA-388396
Cytochrome c-mediated apoptotic response R-HSA-111461
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nervous system development R-HSA-9675108
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Neuronal System R-HSA-112316
Transcriptional Regulation by NPAS4 R-HSA-9634815
RUNX2 regulates bone development R-HSA-8941326
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Transmission across Chemical Synapses R-HSA-112315
Mitotic Prophase R-HSA-68875
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by NTRKs R-HSA-166520
Transcriptional regulation by RUNX2 R-HSA-8878166
Intrinsic Pathway for Apoptosis R-HSA-109606
Signal attenuation R-HSA-74749
Negative regulation of FGFR3 signaling R-HSA-5654732
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
phospho-PLA2 pathway R-HSA-111995
MAP kinase activation R-HSA-450294
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by FGFR R-HSA-190236
G alpha (i) signalling events R-HSA-418594
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
MAPK1 (ERK2) activation R-HSA-112411
Signaling by TGFB family members R-HSA-9006936
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
M Phase R-HSA-68886
ERK/MAPK targets R-HSA-198753
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
Negative regulation of FGFR2 signaling R-HSA-5654727
RHO GTPase Effectors R-HSA-195258
Developmental Biology R-HSA-1266738
Oncogenic MAPK signaling R-HSA-6802957
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
Regulation of PTEN gene transcription R-HSA-8943724
MAPK1 (ERK2) activation R-HSA-112411
Negative regulation of MAPK pathway R-HSA-5675221
MyD88 cascade initiated on plasma membrane R-HSA-975871
Ca-dependent events R-HSA-111996
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Insulin receptor signalling cascade R-HSA-74751
MAPK family signaling cascades R-HSA-5683057
Signaling by Rho GTPases R-HSA-194315
MAP kinase activation R-HSA-450294
Signaling by FGFR2 R-HSA-5654738
Transcriptional regulation by RUNX2 R-HSA-8878166
Leishmania infection R-HSA-9658195
RSK activation R-HSA-444257
Signaling by NTRKs R-HSA-166520
Regulation of HSF1-mediated heat shock response R-HSA-3371453
Cellular response to heat stress R-HSA-3371556
Signaling by NODAL R-HSA-1181150
Negative feedback regulation of MAPK pathway R-HSA-5674499
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR4 R-HSA-5654743
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by Insulin receptor R-HSA-74752
L1CAM interactions R-HSA-373760
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Intracellular signaling by second messengers R-HSA-9006925
MyD88-independent TLR4 cascade R-HSA-166166
Intrinsic Pathway for Apoptosis R-HSA-109606
FCERI mediated MAPK activation R-HSA-2871796
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NCAM signaling for neurite out-growth R-HSA-375165
Apoptosis R-HSA-109581
Signaling by FGFR3 R-HSA-5654741
Signaling by RAS mutants R-HSA-6802949
Growth hormone receptor signaling R-HSA-982772
RNA Polymerase II Transcription R-HSA-73857
Leishmania phagocytosis R-HSA-9664417
Interleukin-17 signaling R-HSA-448424
Apoptotic factor-mediated response R-HSA-111471
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Nervous system development R-HSA-9675108
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Frs2-mediated activation R-HSA-170968
Cell Cycle R-HSA-1640170
Signaling by NTRK1 (TRKA) R-HSA-187037
ESR-mediated signaling R-HSA-8939211
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Transmission across Chemical Synapses R-HSA-112315
Signaling downstream of RAS mutants R-HSA-9649948
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Prolonged ERK activation events R-HSA-169893
Regulation of the apoptosome activity R-HSA-9627069
Cellular responses to stimuli R-HSA-8953897
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Signaling by FGFR R-HSA-190236
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Extra-nuclear estrogen signaling R-HSA-9009391
Infection with Mycobacterium tuberculosis R-HSA-9635486
G alpha (q) signalling events R-HSA-416476
Opioid Signalling R-HSA-111885
Negative regulation of FGFR3 signaling R-HSA-5654732
Signal transduction by L1 R-HSA-445144
Suppression of apoptosis R-HSA-9635465
Activation of the AP-1 family of transcription factors R-HSA-450341
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
MAPK1/MAPK3 signaling R-HSA-5684996
Generic Transcription Pathway R-HSA-212436
Signaling by Interleukins R-HSA-449147
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Programmed Cell Death R-HSA-5357801
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signalling to ERKs R-HSA-187687
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
Disease R-HSA-1643685
phospho-PLA2 pathway R-HSA-111995
GPCR downstream signalling R-HSA-388396
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Mitotic Prophase R-HSA-68875
Immune System R-HSA-168256
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Platelet activation, signaling and aggregation R-HSA-76002
Spry regulation of FGF signaling R-HSA-1295596
Signaling by MAPK mutants R-HSA-9652817
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
RUNX2 regulates bone development R-HSA-8941326
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
NPAS4 regulates expression of target genes R-HSA-9768919
Response of Mtb to phagocytosis R-HSA-9637690
ERKs are inactivated R-HSA-202670
Negative regulation of FGFR1 signaling R-HSA-5654726
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Innate Immune System R-HSA-168249
Transcriptional Regulation by NPAS4 R-HSA-9634815
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Neuronal System R-HSA-112316
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Axon guidance R-HSA-422475
Cellular Senescence R-HSA-2559583
PIP3 activates AKT signaling R-HSA-1257604
G-protein mediated events R-HSA-112040
Signaling by TGFB family members R-HSA-9006936
Formation of apoptosome R-HSA-111458
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by RAF1 mutants R-HSA-9656223
Signaling by TGF-beta Receptor Complex R-HSA-170834
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by Activin R-HSA-1502540
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Parasite infection R-HSA-9664407
Signaling by MAP2K mutants R-HSA-9652169
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signaling by ALK in cancer R-HSA-9700206
FCGR3A-mediated phagocytosis R-HSA-9664422
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
Negative regulation of the PI3K/AKT network R-HSA-199418
MAP2K and MAPK activation R-HSA-5674135
Signal attenuation R-HSA-74749
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Cytochrome c-mediated apoptotic response R-HSA-111461
RAF-independent MAPK1/3 activation R-HSA-112409
Signaling by Nuclear Receptors R-HSA-9006931
Hemostasis R-HSA-109582
G alpha (i) signalling events R-HSA-418594
RAF/MAP kinase cascade R-HSA-5673001
Toll-like Receptor Cascades R-HSA-168898
Post NMDA receptor activation events R-HSA-438064
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Oncogene Induced Senescence R-HSA-2559585
PLC beta mediated events R-HSA-112043
Signaling by GPCR R-HSA-372790
M Phase R-HSA-68886
Recycling pathway of L1 R-HSA-437239
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PTEN Regulation R-HSA-6807070
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Hemostasis R-HSA-109582
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926
ERKs are inactivated R-HSA-202670
Neuronal System R-HSA-112316
Neutrophil degranulation R-HSA-6798695
MyD88-independent TLR4 cascade R-HSA-166166
Negative regulation of FGFR1 signaling R-HSA-5654726
Toll-like Receptor Cascades R-HSA-168898
Signaling by TGF-beta Receptor Complex R-HSA-170834
M Phase R-HSA-68886
RUNX2 regulates osteoblast differentiation R-HSA-8940973
Negative regulation of FGFR4 signaling R-HSA-5654733
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Disease R-HSA-1643685
Advanced glycosylation endproduct receptor signaling R-HSA-879415
Negative regulation of the PI3K/AKT network R-HSA-199418
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
MAPK family signaling cascades R-HSA-5683057
Cytochrome c-mediated apoptotic response R-HSA-111461
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of PTEN gene transcription R-HSA-8943724
Signaling by TGFB family members R-HSA-9006936
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Cellular response to heat stress R-HSA-3371556
Insulin receptor signalling cascade R-HSA-74751
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Transmission across Chemical Synapses R-HSA-112315
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Axon guidance R-HSA-422475
FCERI mediated MAPK activation R-HSA-2871796
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Spry regulation of FGF signaling R-HSA-1295596
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795
FCGR3A-mediated phagocytosis R-HSA-9664422
Signaling by FGFR3 R-HSA-5654741
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Extra-nuclear estrogen signaling R-HSA-9009391
Leishmania infection R-HSA-9658195
Oncogenic MAPK signaling R-HSA-6802957
RAF/MAP kinase cascade R-HSA-5673001
PLC beta mediated events R-HSA-112043
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Infection with Mycobacterium tuberculosis R-HSA-9635486
ERK/MAPK targets R-HSA-198753
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742
Signal attenuation R-HSA-74749
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by FGFR1 R-HSA-5654736
RHO GTPase Effectors R-HSA-195258
Transcriptional regulation by RUNX2 R-HSA-8878166
Signal transduction by L1 R-HSA-445144
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793
Mitotic Prophase R-HSA-68875
Growth hormone receptor signaling R-HSA-982772
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ca-dependent events R-HSA-111996
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by RAF1 mutants R-HSA-9656223
Leishmania phagocytosis R-HSA-9664417
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
RUNX2 regulates bone development R-HSA-8941326
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NODAL R-HSA-1181150
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635
Apoptotic factor-mediated response R-HSA-111471
Gene expression (Transcription) R-HSA-74160
phospho-PLA2 pathway R-HSA-111995
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Nervous system development R-HSA-9675108
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
Regulation of the apoptosome activity R-HSA-9627069
Suppression of apoptosis R-HSA-9635465
Cell Cycle R-HSA-1640170
Oncogene Induced Senescence R-HSA-2559585
Recycling pathway of L1 R-HSA-437239
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by MAPK mutants R-HSA-9652817
Signaling by FGFR2 R-HSA-5654738
RNA Polymerase II Transcription R-HSA-73857
GPCR downstream signalling R-HSA-388396
Signaling by MAP2K mutants R-HSA-9652169
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88 dependent cascade initiated on endosome R-HSA-975155
Parasite infection R-HSA-9664407
PTEN Regulation R-HSA-6807070
Frs2-mediated activation R-HSA-170968
RAF-independent MAPK1/3 activation R-HSA-112409
Post NMDA receptor activation events R-HSA-438064
Signaling by Nuclear Receptors R-HSA-9006931
NPAS4 regulates expression of target genes R-HSA-9768919
RSK activation R-HSA-444257
G alpha (i) signalling events R-HSA-418594
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
NCAM signaling for neurite out-growth R-HSA-375165
Signaling by FGFR R-HSA-190236
Response of Mtb to phagocytosis R-HSA-9637690
Programmed Cell Death R-HSA-5357801
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by FGFR4 R-HSA-5654743
Signaling by Rho GTPases R-HSA-194315
Signaling by GPCR R-HSA-372790
Negative regulation of FGFR3 signaling R-HSA-5654732
G alpha (q) signalling events R-HSA-416476
Signalling to ERKs R-HSA-187687
Signaling by Insulin receptor R-HSA-74752
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAP2K and MAPK activation R-HSA-5674135
Signaling by Activin R-HSA-1502540
Infectious disease R-HSA-5663205
ESR-mediated signaling R-HSA-8939211
L1CAM interactions R-HSA-373760
Negative regulation of MAPK pathway R-HSA-5675221
Opioid Signalling R-HSA-111885
Innate Immune System R-HSA-168249
Activation of NMDA receptors and postsynaptic events R-HSA-442755
RHO GTPases Activate WASPs and WAVEs R-HSA-5663213
G-protein mediated events R-HSA-112040
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482
Apoptosis R-HSA-109581
Developmental Biology R-HSA-1266738
MAP kinase activation R-HSA-450294
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of HSF1-mediated heat shock response R-HSA-3371453
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796
Platelet activation, signaling and aggregation R-HSA-76002
MAPK1 (ERK2) activation R-HSA-112411
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Formation of apoptosome R-HSA-111458
Signaling by ALK in cancer R-HSA-9700206
Prolonged ERK activation events R-HSA-169893
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling downstream of RAS mutants R-HSA-9649948
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Negative regulation of FGFR2 signaling R-HSA-5654727
Transcriptional Regulation by NPAS4 R-HSA-9634815
Signaling by RAS mutants R-HSA-6802949

Expression Atlas ENSG00000100030
LRG display in Ensembl gene LRG_786
NCBI gene (formerly Entrezgene) 5594
GeneCards 6871
HGNC Symbol HGNC:6871
MIM gene 176948
MIM morbid 619087
UniProtKB Gene Name Q1HBJ4
WikiGene 5594
Gene: TPH1
Ensembl ID : ENSG00000129167
Description: tryptophan hydroxylase 1
Gene Synonyms: TPH,TPRH
1 APIs:
257 Possible Orthologues:

Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
NGF-stimulated transcription R-HSA-9031628
Serotonin and melatonin biosynthesis R-HSA-209931
Signaling by NTRKs R-HSA-166520
Metabolism of amine-derived hormones R-HSA-209776
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRKs R-HSA-166520
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Metabolism of amine-derived hormones R-HSA-209776
Serotonin and melatonin biosynthesis R-HSA-209931
NGF-stimulated transcription R-HSA-9031628
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRKs R-HSA-166520
Metabolism of amine-derived hormones R-HSA-209776
Metabolism R-HSA-1430728
Serotonin and melatonin biosynthesis R-HSA-209931
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
NGF-stimulated transcription R-HSA-9031628
Serotonin and melatonin biosynthesis R-HSA-209931
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Metabolism of amine-derived hormones R-HSA-209776
Signaling by NTRKs R-HSA-166520
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
NGF-stimulated transcription R-HSA-9031628
Metabolism R-HSA-1430728
Metabolism of amine-derived hormones R-HSA-209776
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signal Transduction R-HSA-162582
NGF-stimulated transcription R-HSA-9031628
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NTRK1 (TRKA) R-HSA-187037
Serotonin and melatonin biosynthesis R-HSA-209931
Signaling by NTRKs R-HSA-166520
NGF-stimulated transcription R-HSA-9031628
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of amine-derived hormones R-HSA-209776
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Serotonin and melatonin biosynthesis R-HSA-209931
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism R-HSA-1430728
Serotonin and melatonin biosynthesis R-HSA-209931
NGF-stimulated transcription R-HSA-9031628
Metabolism of amine-derived hormones R-HSA-209776
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism of amino acids and derivatives R-HSA-71291
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRKs R-HSA-166520
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Serotonin and melatonin biosynthesis R-HSA-209931
Metabolism of amine-derived hormones R-HSA-209776
Signaling by NTRK1 (TRKA) R-HSA-187037
Serotonin and melatonin biosynthesis R-HSA-209931
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism of amine-derived hormones R-HSA-209776
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRKs R-HSA-166520
Metabolism R-HSA-1430728
Signaling by NTRKs R-HSA-166520
Serotonin and melatonin biosynthesis R-HSA-209931
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of amine-derived hormones R-HSA-209776
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
NGF-stimulated transcription R-HSA-9031628
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism R-HSA-1430728
Metabolism of amine-derived hormones R-HSA-209776
Serotonin and melatonin biosynthesis R-HSA-209931
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRKs R-HSA-166520
NGF-stimulated transcription R-HSA-9031628
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Receptor Tyrosine Kinases R-HSA-9006934

Expression Atlas ENSG00000129167
NCBI gene (formerly Entrezgene) 7166
GeneCards 12008
HGNC Symbol HGNC:12008
MIM gene 191060
UniProtKB Gene Name P17752
WikiGene 7166
Gene: TYMP
Ensembl ID : ENSG00000025708
Description: thymidine phosphorylase
Gene Synonyms: ECGF1,MNGIE
1 APIs:
173 Possible Orthologues:

Pyrimidine salvage R-HSA-73614
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Pyrimidine salvage R-HSA-73614
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Nucleotide salvage R-HSA-8956321
Nucleotide catabolism R-HSA-8956319
Metabolism R-HSA-1430728
Pyrimidine salvage R-HSA-73614
Metabolism R-HSA-1430728
Nucleotide salvage R-HSA-8956321
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Pyrimidine salvage R-HSA-73614
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Pyrimidine salvage R-HSA-73614
Pyrimidine catabolism R-HSA-73621
Nucleotide salvage R-HSA-8956321
Nucleotide catabolism R-HSA-8956319
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Metabolism of nucleotides R-HSA-15869
Pyrimidine salvage R-HSA-73614
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Pyrimidine salvage R-HSA-73614
Metabolism of nucleotides R-HSA-15869
Pyrimidine catabolism R-HSA-73621
Nucleotide salvage R-HSA-8956321
Pyrimidine salvage R-HSA-73614
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Nucleotide salvage R-HSA-8956321
Pyrimidine catabolism R-HSA-73621
Nucleotide catabolism R-HSA-8956319
Metabolism R-HSA-1430728
Pyrimidine salvage R-HSA-73614
Nucleotide salvage R-HSA-8956321
Metabolism R-HSA-1430728
Pyrimidine salvage R-HSA-73614
Nucleotide catabolism R-HSA-8956319
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869

Expression Atlas ENSG00000025708
LRG display in Ensembl gene LRG_727
NCBI gene (formerly Entrezgene) 1890
GeneCards 3148
HGNC Symbol HGNC:3148
MIM gene 131222
MIM morbid 603041
UniProtKB Gene Name P19971
WikiGene 1890
Gene: AKR1B1
Ensembl ID : ENSG00000085662
Description: aldo-keto reductase family 1 member B
Gene Synonyms: ALDR1,AR
4 APIs:
391 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Metabolism of carbohydrates R-HSA-71387
Fructose biosynthesis R-HSA-5652227
Fructose metabolism R-HSA-5652084
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Pregnenolone biosynthesis R-HSA-196108
Fructose biosynthesis R-HSA-5652227
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroids R-HSA-8957322
Metabolism of carbohydrates R-HSA-71387
Fructose metabolism R-HSA-5652084
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Metabolism of steroids R-HSA-8957322
Pregnenolone biosynthesis R-HSA-196108
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Fructose biosynthesis R-HSA-5652227
Metabolism of carbohydrates R-HSA-71387
Metabolism R-HSA-1430728
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Fructose metabolism R-HSA-5652084
Fructose metabolism R-HSA-5652084
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Pregnenolone biosynthesis R-HSA-196108
Fructose biosynthesis R-HSA-5652227
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroid hormones R-HSA-196071
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Pregnenolone biosynthesis R-HSA-196108
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroid hormones R-HSA-196071
Fructose metabolism R-HSA-5652084
Metabolism of carbohydrates R-HSA-71387
Metabolism of lipids R-HSA-556833
Fructose biosynthesis R-HSA-5652227
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Metabolism of carbohydrates R-HSA-71387
Fructose metabolism R-HSA-5652084
Fructose biosynthesis R-HSA-5652227
Metabolism R-HSA-1430728
Metabolism of carbohydrates R-HSA-71387
Metabolism of steroids R-HSA-8957322
Fructose metabolism R-HSA-5652084
Pregnenolone biosynthesis R-HSA-196108
Metabolism of steroid hormones R-HSA-196071
Fructose biosynthesis R-HSA-5652227
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833

Expression Atlas ENSG00000085662
NCBI gene (formerly Entrezgene) 231
GeneCards 381
HGNC Symbol HGNC:381
MIM gene 103880
UniProtKB Gene Name P15121
WikiGene 231
Gene: SEM1
Ensembl ID : ENSG00000127922
Description: SEM1 26S proteasome subunit
Gene Synonyms: C7ORF76,DSS1,ECD,FLJ42280,PSMD15,SHFD1,SHFDG1,SHFM1,SHSF1
5 APIs:
156 Possible Orthologues:

Synthesis of DNA R-HSA-69239
Degradation of AXIN R-HSA-4641257
Metabolism R-HSA-1430728
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Metabolism R-HSA-1430728
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Post-translational protein modification R-HSA-597592
Programmed Cell Death R-HSA-5357801
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
TCR signaling R-HSA-202403
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of GLI2 by the proteasome R-HSA-5610783
G1/S Transition R-HSA-69206
Mitotic Metaphase and Anaphase R-HSA-2555396
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Homology Directed Repair R-HSA-5693538
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX3 expression and activity R-HSA-8941858
C-type lectin receptors (CLRs) R-HSA-5621481
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Degradation of GLI1 by the proteasome R-HSA-5610780
FCERI mediated NF-kB activation R-HSA-2871837
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of amino acids and derivatives R-HSA-71291
S Phase R-HSA-69242
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Hh mutants are degraded by ERAD R-HSA-5362768
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of expression of SLITs and ROBOs R-HSA-9010553
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle, Mitotic R-HSA-69278
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Asymmetric localization of PCP proteins R-HSA-4608870
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Neddylation R-HSA-8951664
TCF dependent signaling in response to WNT R-HSA-201681
DNA Replication R-HSA-69306
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent DNA Damage Response R-HSA-69610
DNA Double-Strand Break Repair R-HSA-5693532
Developmental Biology R-HSA-1266738
Degradation of DVL R-HSA-4641258
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Assembly of the pre-replicative complex R-HSA-68867
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
UCH proteinases R-HSA-5689603
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G1 phase and G1/S transition R-HSA-453279
Gene expression (Transcription) R-HSA-74160
MAPK1/MAPK3 signaling R-HSA-5684996
Defective CFTR causes cystic fibrosis R-HSA-5678895
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
HDR through Homologous Recombination (HRR) R-HSA-5685942
Intracellular signaling by second messengers R-HSA-9006925
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transport of small molecules R-HSA-382551
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of beta-catenin by the destruction complex R-HSA-195253
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Interleukin-1 family signaling R-HSA-446652
Interleukin-1 signaling R-HSA-9020702
Hh mutants abrogate ligand secretion R-HSA-5387390
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Mitotic G2-G2/M phases R-HSA-453274
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
PIP3 activates AKT signaling R-HSA-1257604
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by Interleukins R-HSA-449147
Infectious disease R-HSA-5663205
Ub-specific processing proteases R-HSA-5689880
Nervous system development R-HSA-9675108
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
M Phase R-HSA-68886
Negative regulation of NOTCH4 signaling R-HSA-9604323
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Adaptive Immune System R-HSA-1280218
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
DNA Repair R-HSA-73894
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Hedgehog 'on' state R-HSA-5632684
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
Resolution of D-Loop Structures R-HSA-5693537
G2/M Checkpoints R-HSA-69481
MAPK family signaling cascades R-HSA-5683057
Signaling by Hedgehog R-HSA-5358351
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
Disorders of transmembrane transporters R-HSA-5619115
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Signal Transduction R-HSA-162582
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular response to chemical stress R-HSA-9711123
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
HIV Infection R-HSA-162906
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of DNA repair R-HSA-9675135
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Mitotic Anaphase R-HSA-68882
Cytokine Signaling in Immune system R-HSA-1280215
p53-Dependent G1 DNA Damage Response R-HSA-69563
Assembly of the pre-replicative complex R-HSA-68867
Disorders of transmembrane transporters R-HSA-5619115
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Hh mutants abrogate ligand secretion R-HSA-5387390
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
DNA Replication R-HSA-69306
S Phase R-HSA-69242
Regulation of RAS by GAPs R-HSA-5658442
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neddylation R-HSA-8951664
DNA Replication Pre-Initiation R-HSA-69002
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Metabolism of polyamines R-HSA-351202
Generic Transcription Pathway R-HSA-212436
RAF/MAP kinase cascade R-HSA-5673001
PCP/CE pathway R-HSA-4086400
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Apoptosis R-HSA-109581
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK6/MAPK4 signaling R-HSA-5687128
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of beta-catenin by the destruction complex R-HSA-195253
HIV Infection R-HSA-162906
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signal Transduction R-HSA-162582
Homology Directed Repair R-HSA-5693538
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Vpu mediated degradation of CD4 R-HSA-180534
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
G2/M Transition R-HSA-69275
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to hypoxia R-HSA-1234174
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Metabolism of RNA R-HSA-8953854
Cellular response to chemical stress R-HSA-9711123
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
CLEC7A (Dectin-1) signaling R-HSA-5607764
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
Signaling by ROBO receptors R-HSA-376176
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
G1/S DNA Damage Checkpoints R-HSA-69615
Nervous system development R-HSA-9675108
Cell Cycle Checkpoints R-HSA-69620
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by NOTCH4 R-HSA-9013694
Signaling by NOTCH R-HSA-157118
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
HDR through Homologous Recombination (HRR) R-HSA-5685942
TCF dependent signaling in response to WNT R-HSA-201681
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Hedgehog ligand biogenesis R-HSA-5358346
Diseases of DNA repair R-HSA-9675135
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Double-Strand Break Repair R-HSA-5693532
G1/S Transition R-HSA-69206
Hh mutants are degraded by ERAD R-HSA-5362768
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Activation of NF-kappaB in B cells R-HSA-1169091
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Resolution of D-Loop Structures R-HSA-5693537
Signaling by Interleukins R-HSA-449147
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism R-HSA-1430728
Regulation of PTEN stability and activity R-HSA-8948751
Nuclear events mediated by NFE2L2 R-HSA-9759194
RNA Polymerase II Transcription R-HSA-73857
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G1 phase and G1/S transition R-HSA-453279
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Downstream TCR signaling R-HSA-202424
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
Synthesis of DNA R-HSA-69239
Metabolism of proteins R-HSA-392499
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
ABC transporter disorders R-HSA-5619084
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
Transport of small molecules R-HSA-382551
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Infectious disease R-HSA-5663205
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
G2/M Checkpoints R-HSA-69481
ER-Phagosome pathway R-HSA-1236974
Regulation of Apoptosis R-HSA-169911
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Switching of origins to a post-replicative state R-HSA-69052
Intracellular signaling by second messengers R-HSA-9006925
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Post-translational protein modification R-HSA-597592
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Hedgehog 'off' state R-HSA-5610787
C-type lectin receptors (CLRs) R-HSA-5621481
Adaptive Immune System R-HSA-1280218
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Ub-specific processing proteases R-HSA-5689880
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Signaling by WNT R-HSA-195721
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Transcriptional regulation by RUNX3 R-HSA-8878159
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Regulation of RUNX2 expression and activity R-HSA-8939902
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Orc1 removal from chromatin R-HSA-68949
Developmental Biology R-HSA-1266738
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
Metabolism of amino acids and derivatives R-HSA-71291
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by WNT R-HSA-195721
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Gene expression (Transcription) R-HSA-74160
Cellular response to hypoxia R-HSA-1234174
HDR through Homologous Recombination (HRR) R-HSA-5685942
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
PTEN Regulation R-HSA-6807070
Assembly of the pre-replicative complex R-HSA-68867
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Transition R-HSA-69275
Cyclin E associated events during G1/S transition R-HSA-69202
G2/M Checkpoints R-HSA-69481
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NOTCH R-HSA-157118
FCERI mediated NF-kB activation R-HSA-2871837
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
HIV Infection R-HSA-162906
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Metabolism of RNA R-HSA-8953854
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cell Cycle R-HSA-1640170
DNA Double-Strand Break Repair R-HSA-5693532
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Diseases of DNA repair R-HSA-9675135
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
Class I MHC mediated antigen processing & presentation R-HSA-983169
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Generic Transcription Pathway R-HSA-212436
Transport of small molecules R-HSA-382551
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Intracellular signaling by second messengers R-HSA-9006925
ER-Phagosome pathway R-HSA-1236974
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
CLEC7A (Dectin-1) signaling R-HSA-5607764
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Mitotic G1 phase and G1/S transition R-HSA-453279
Innate Immune System R-HSA-168249
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream TCR signaling R-HSA-202424
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
ABC-family proteins mediated transport R-HSA-382556
Metabolism of polyamines R-HSA-351202
Adaptive Immune System R-HSA-1280218
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle, Mitotic R-HSA-69278
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Regulation of mitotic cell cycle R-HSA-453276
G1/S DNA Damage Checkpoints R-HSA-69615
Host Interactions of HIV factors R-HSA-162909
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Neddylation R-HSA-8951664
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication Pre-Initiation R-HSA-69002
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RAS by GAPs R-HSA-5658442
Signaling by ROBO receptors R-HSA-376176
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
p53-Dependent G1 DNA Damage Response R-HSA-69563
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Vpu mediated degradation of CD4 R-HSA-180534
DNA Repair R-HSA-73894
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Apoptosis R-HSA-109581
Signaling by Hedgehog R-HSA-5358351
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX3 R-HSA-8878159
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
PCP/CE pathway R-HSA-4086400
Degradation of DVL R-HSA-4641258
Degradation of AXIN R-HSA-4641257
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
DNA Replication R-HSA-69306
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Infectious disease R-HSA-5663205
Resolution of D-Loop Structures R-HSA-5693537
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
RNA Polymerase II Transcription R-HSA-73857
Nuclear events mediated by NFE2L2 R-HSA-9759194
Degradation of beta-catenin by the destruction complex R-HSA-195253
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Homology Directed Repair R-HSA-5693538
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog 'off' state R-HSA-5610787
Disorders of transmembrane transporters R-HSA-5619115
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH4 R-HSA-9013694
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Programmed Cell Death R-HSA-5357801
Nervous system development R-HSA-9675108
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of proteins R-HSA-392499
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Vif-mediated degradation of APOBEC3G R-HSA-180585
G2/M Checkpoints R-HSA-69481
PCP/CE pathway R-HSA-4086400
p53-Independent DNA Damage Response R-HSA-69610
Metabolism R-HSA-1430728
Diseases of DNA repair R-HSA-9675135
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
DNA Replication Pre-Initiation R-HSA-69002
MAPK1/MAPK3 signaling R-HSA-5684996
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Interleukin-1 family signaling R-HSA-446652
DNA Double-Strand Break Repair R-HSA-5693532
Signaling by Interleukins R-HSA-449147
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
Adaptive Immune System R-HSA-1280218
Mitotic Anaphase R-HSA-68882
Signaling by Hedgehog R-HSA-5358351
Cellular response to chemical stress R-HSA-9711123
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Infectious disease R-HSA-5663205
Regulation of Apoptosis R-HSA-169911
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'on' state R-HSA-5632684
Hedgehog 'off' state R-HSA-5610787
HIV Infection R-HSA-162906
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disorders of transmembrane transporters R-HSA-5619115
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic G1 phase and G1/S transition R-HSA-453279
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Transcriptional regulation by RUNX2 R-HSA-8878166
PTEN Regulation R-HSA-6807070
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Separation of Sister Chromatids R-HSA-2467813
Cyclin E associated events during G1/S transition R-HSA-69202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
KEAP1-NFE2L2 pathway R-HSA-9755511
Class I MHC mediated antigen processing & presentation R-HSA-983169
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G1/S DNA Damage Checkpoints R-HSA-69615
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Synthesis of DNA R-HSA-69239
UCH proteinases R-HSA-5689603
TCF dependent signaling in response to WNT R-HSA-201681
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Disease R-HSA-1643685
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Mitotic G2-G2/M phases R-HSA-453274
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
Assembly of the pre-replicative complex R-HSA-68867
DNA Replication R-HSA-69306
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
RNA Polymerase II Transcription R-HSA-73857
Resolution of D-Loop Structures R-HSA-5693537
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Degradation of beta-catenin by the destruction complex R-HSA-195253
Generic Transcription Pathway R-HSA-212436
HDR through Homologous Recombination (HRR) R-HSA-5685942
G1/S Transition R-HSA-69206
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Metabolism of amino acids and derivatives R-HSA-71291
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Homology Directed Repair R-HSA-5693538
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC-family proteins mediated transport R-HSA-382556
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle, Mitotic R-HSA-69278
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Hedgehog ligand biogenesis R-HSA-5358346
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stimuli R-HSA-8953897
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
ER-Phagosome pathway R-HSA-1236974
MAPK family signaling cascades R-HSA-5683057
Negative regulation of NOTCH4 signaling R-HSA-9604323
Deubiquitination R-HSA-5688426
Stabilization of p53 R-HSA-69541
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
M Phase R-HSA-68886
Cell Cycle Checkpoints R-HSA-69620
Regulation of RUNX2 expression and activity R-HSA-8939902
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of RNA R-HSA-8953854
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX3 R-HSA-8878159
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of AXIN R-HSA-4641257
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
DNA Repair R-HSA-73894
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
RAF/MAP kinase cascade R-HSA-5673001
Switching of origins to a post-replicative state R-HSA-69052
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
G2/M Transition R-HSA-69275
TCR signaling R-HSA-202403
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH R-HSA-157118
Regulation of PTEN stability and activity R-HSA-8948751
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Innate Immune System R-HSA-168249
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Interleukin-1 signaling R-HSA-9020702
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
HIV Infection R-HSA-162906
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Host Interactions of HIV factors R-HSA-162909
Stabilization of p53 R-HSA-69541
Cellular response to chemical stress R-HSA-9711123
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
FCERI mediated NF-kB activation R-HSA-2871837
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
DNA Double-Strand Break Repair R-HSA-5693532
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Post-translational protein modification R-HSA-597592
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
Homology Directed Repair R-HSA-5693538
PCP/CE pathway R-HSA-4086400
Vpu mediated degradation of CD4 R-HSA-180534
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
Immune System R-HSA-168256
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of DVL R-HSA-4641258
Degradation of AXIN R-HSA-4641257
Downstream TCR signaling R-HSA-202424
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Developmental Biology R-HSA-1266738
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Hh mutants are degraded by ERAD R-HSA-5362768
Hedgehog 'on' state R-HSA-5632684
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Disorders of transmembrane transporters R-HSA-5619115
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Resolution of D-Loop Structures R-HSA-5693537
Axon guidance R-HSA-422475
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cell Cycle, Mitotic R-HSA-69278
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
MAPK family signaling cascades R-HSA-5683057
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Intracellular signaling by second messengers R-HSA-9006925
G2/M Checkpoints R-HSA-69481
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Transcriptional regulation by RUNX3 R-HSA-8878159
DNA Repair R-HSA-73894
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of RUNX3 expression and activity R-HSA-8941858
Signal Transduction R-HSA-162582
G1/S Transition R-HSA-69206
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Switching of origins to a post-replicative state R-HSA-69052
ER-Phagosome pathway R-HSA-1236974
Antigen processing-Cross presentation R-HSA-1236975
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PIP3 activates AKT signaling R-HSA-1257604
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Signaling by Hedgehog R-HSA-5358351
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Metabolism of polyamines R-HSA-351202
Diseases of DNA repair R-HSA-9675135
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
DNA Replication R-HSA-69306
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK1/MAPK3 signaling R-HSA-5684996
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Neddylation R-HSA-8951664
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Assembly of the pre-replicative complex R-HSA-68867
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of mitotic cell cycle R-HSA-453276
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by ROBO receptors R-HSA-376176
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RAF/MAP kinase cascade R-HSA-5673001
Regulation of RAS by GAPs R-HSA-5658442
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog 'off' state R-HSA-5610787
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Negative regulation of NOTCH4 signaling R-HSA-9604323
HDR through Homologous Recombination (HRR) R-HSA-5685942
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
ABC-family proteins mediated transport R-HSA-382556
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Adaptive Immune System R-HSA-1280218
Hedgehog ligand biogenesis R-HSA-5358346
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Mitotic Metaphase and Anaphase R-HSA-2555396
G2/M Checkpoints R-HSA-69481
PTEN Regulation R-HSA-6807070
Mitotic G2-G2/M phases R-HSA-453274
Separation of Sister Chromatids R-HSA-2467813
Hedgehog 'off' state R-HSA-5610787
Regulation of PTEN stability and activity R-HSA-8948751
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Innate Immune System R-HSA-168249
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Degradation of AXIN R-HSA-4641257
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by NOTCH4 R-HSA-9013694
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S Transition R-HSA-69206
Nuclear events mediated by NFE2L2 R-HSA-9759194
UCH proteinases R-HSA-5689603
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular responses to stress R-HSA-2262752
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Transport of small molecules R-HSA-382551
Regulation of Apoptosis R-HSA-169911
Signaling by Interleukins R-HSA-449147
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of beta-catenin by the destruction complex R-HSA-195253
Negative regulation of NOTCH4 signaling R-HSA-9604323
MAPK6/MAPK4 signaling R-HSA-5687128
Axon guidance R-HSA-422475
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Impaired BRCA2 binding to RAD51 R-HSA-9709570
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
Nervous system development R-HSA-9675108
Cellular response to chemical stress R-HSA-9711123
S Phase R-HSA-69242
Hedgehog 'on' state R-HSA-5632684
Class I MHC mediated antigen processing & presentation R-HSA-983169
Signaling by NOTCH R-HSA-157118
ABC transporter disorders R-HSA-5619084
Synthesis of DNA R-HSA-69239
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Stabilization of p53 R-HSA-69541
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Metabolism of RNA R-HSA-8953854
Downstream TCR signaling R-HSA-202424
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
KEAP1-NFE2L2 pathway R-HSA-9755511
Transcriptional regulation by RUNX3 R-HSA-8878159
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RAF/MAP kinase cascade R-HSA-5673001
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ROBO receptors R-HSA-376176
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to hypoxia R-HSA-1234174
HIV Infection R-HSA-162906
CLEC7A (Dectin-1) signaling R-HSA-5607764
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
DNA Double-Strand Break Repair R-HSA-5693532
Deubiquitination R-HSA-5688426
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Defective CFTR causes cystic fibrosis R-HSA-5678895
Adaptive Immune System R-HSA-1280218
Resolution of D-Loop Structures R-HSA-5693537
Regulation of mitotic cell cycle R-HSA-453276
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Degradation of DVL R-HSA-4641258
Disorders of transmembrane transporters R-HSA-5619115
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX2 R-HSA-8878166
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Asymmetric localization of PCP proteins R-HSA-4608870
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Orc1 removal from chromatin R-HSA-68949
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
FCERI mediated NF-kB activation R-HSA-2871837
HDR through Homologous Recombination (HRR) R-HSA-5685942
TCF dependent signaling in response to WNT R-HSA-201681
Vif-mediated degradation of APOBEC3G R-HSA-180585
DNA Replication Pre-Initiation R-HSA-69002
Host Interactions of HIV factors R-HSA-162909
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
PCP/CE pathway R-HSA-4086400
Hh mutants abrogate ligand secretion R-HSA-5387390
M Phase R-HSA-68886
Diseases of DNA repair R-HSA-9675135
Regulation of RUNX2 expression and activity R-HSA-8939902
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Metabolism of polyamines R-HSA-351202
Cytokine Signaling in Immune system R-HSA-1280215
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Hh mutants are degraded by ERAD R-HSA-5362768
Apoptosis R-HSA-109581
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle Checkpoints R-HSA-69620
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
C-type lectin receptors (CLRs) R-HSA-5621481
Neddylation R-HSA-8951664
Cell Cycle, Mitotic R-HSA-69278
TCR signaling R-HSA-202403
Infectious disease R-HSA-5663205
NIK-->noncanonical NF-kB signaling R-HSA-5676590
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ER-Phagosome pathway R-HSA-1236974
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX1 R-HSA-8878171
DNA Repair R-HSA-73894
Metabolism of proteins R-HSA-392499
Signaling by WNT R-HSA-195721
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
Post-translational protein modification R-HSA-597592
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
RNA Polymerase II Transcription R-HSA-73857
Assembly of the pre-replicative complex R-HSA-68867
Switching of origins to a post-replicative state R-HSA-69052
Homology Directed Repair R-HSA-5693538
Cyclin E associated events during G1/S transition R-HSA-69202
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Diseases of DNA repair R-HSA-9675135
Separation of Sister Chromatids R-HSA-2467813
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
Impaired BRCA2 binding to RAD51 R-HSA-9709570
ER-Phagosome pathway R-HSA-1236974
Degradation of beta-catenin by the destruction complex R-HSA-195253
Disorders of transmembrane transporters R-HSA-5619115
Regulation of RAS by GAPs R-HSA-5658442
Beta-catenin independent WNT signaling R-HSA-3858494
Deubiquitination R-HSA-5688426
HDR through Homologous Recombination (HRR) R-HSA-5685942
MAPK family signaling cascades R-HSA-5683057
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Cell Cycle Checkpoints R-HSA-69620
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of proteins R-HSA-392499
Resolution of D-Loop Structures R-HSA-5693537
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
PTEN Regulation R-HSA-6807070
Generic Transcription Pathway R-HSA-212436
Degradation of GLI1 by the proteasome R-HSA-5610780
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vpu mediated degradation of CD4 R-HSA-180534
Switching of origins to a post-replicative state R-HSA-69052
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of Apoptosis R-HSA-169911
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Downstream TCR signaling R-HSA-202424
Cellular response to hypoxia R-HSA-1234174
Cell Cycle, Mitotic R-HSA-69278
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to chemical stress R-HSA-9711123
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
UCH proteinases R-HSA-5689603
Synthesis of DNA R-HSA-69239
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hedgehog 'off' state R-HSA-5610787
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of mitotic cell cycle R-HSA-453276
DNA Replication R-HSA-69306
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of DVL R-HSA-4641258
p53-Independent DNA Damage Response R-HSA-69610
Programmed Cell Death R-HSA-5357801
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
NIK-->noncanonical NF-kB signaling R-HSA-5676590
S Phase R-HSA-69242
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Signaling by Hedgehog R-HSA-5358351
Innate Immune System R-HSA-168249
Gene expression (Transcription) R-HSA-74160
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Assembly of the pre-replicative complex R-HSA-68867
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
HIV Infection R-HSA-162906
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
DNA Repair R-HSA-73894
PCP/CE pathway R-HSA-4086400
Cellular responses to stimuli R-HSA-8953897
Class I MHC mediated antigen processing & presentation R-HSA-983169
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of RUNX3 expression and activity R-HSA-8941858
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Interleukins R-HSA-449147
Homology Directed Repair R-HSA-5693538
Disease R-HSA-1643685
TCR signaling R-HSA-202403
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
DNA Double-Strand Break Repair R-HSA-5693532
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX1 R-HSA-8878171
Transcriptional regulation by RUNX2 R-HSA-8878166
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Orc1 removal from chromatin R-HSA-68949
Adaptive Immune System R-HSA-1280218
Negative regulation of NOTCH4 signaling R-HSA-9604323
PIP3 activates AKT signaling R-HSA-1257604
Stabilization of p53 R-HSA-69541
Metabolism of RNA R-HSA-8953854
Apoptosis R-HSA-109581
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transport of small molecules R-HSA-382551
Post-translational protein modification R-HSA-597592
DNA Replication Pre-Initiation R-HSA-69002
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Neddylation R-HSA-8951664
FCERI mediated NF-kB activation R-HSA-2871837
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 signaling R-HSA-9020702
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH4 R-HSA-9013694
Nuclear events mediated by NFE2L2 R-HSA-9759194
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of polyamines R-HSA-351202
Activation of NF-kappaB in B cells R-HSA-1169091
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cell Cycle R-HSA-1640170
Vif-mediated degradation of APOBEC3G R-HSA-180585
Post-translational protein modification R-HSA-597592
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Cell Cycle Checkpoints R-HSA-69620
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Transcriptional regulation by RUNX1 R-HSA-8878171
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transport of small molecules R-HSA-382551
Neddylation R-HSA-8951664
Cellular responses to stimuli R-HSA-8953897
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Generic Transcription Pathway R-HSA-212436
PCP/CE pathway R-HSA-4086400
Cyclin E associated events during G1/S transition R-HSA-69202
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Resolution of D-Loop Structures R-HSA-5693537
Hedgehog ligand biogenesis R-HSA-5358346
G2/M Checkpoints R-HSA-69481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Orc1 removal from chromatin R-HSA-68949
Regulation of mitotic cell cycle R-HSA-453276
Innate Immune System R-HSA-168249
MAPK6/MAPK4 signaling R-HSA-5687128
Negative regulation of NOTCH4 signaling R-HSA-9604323
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Metabolism of amino acids and derivatives R-HSA-71291
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of DVL R-HSA-4641258
Antigen processing-Cross presentation R-HSA-1236975
HDR through Homologous Recombination (HRR) R-HSA-5685942
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signaling by Interleukins R-HSA-449147
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
PTEN Regulation R-HSA-6807070
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Regulation of Apoptosis R-HSA-169911
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
DNA Replication R-HSA-69306
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Deubiquitination R-HSA-5688426
Intracellular signaling by second messengers R-HSA-9006925
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of RUNX2 expression and activity R-HSA-8939902
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Immune System R-HSA-168256
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
DNA Double-Strand Break Repair R-HSA-5693532
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Interleukin-1 signaling R-HSA-9020702
MAPK family signaling cascades R-HSA-5683057
Adaptive Immune System R-HSA-1280218
Mitotic G1 phase and G1/S transition R-HSA-453279
Ub-specific processing proteases R-HSA-5689880
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RUNX3 expression and activity R-HSA-8941858
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Developmental Biology R-HSA-1266738
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Disease R-HSA-1643685
RAF/MAP kinase cascade R-HSA-5673001
Beta-catenin independent WNT signaling R-HSA-3858494
DNA Replication Pre-Initiation R-HSA-69002
Diseases of DNA repair R-HSA-9675135
Signaling by ROBO receptors R-HSA-376176
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Homology Directed Repair R-HSA-5693538
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by NOTCH R-HSA-157118
Degradation of beta-catenin by the destruction complex R-HSA-195253
FCERI mediated NF-kB activation R-HSA-2871837
ER-Phagosome pathway R-HSA-1236974
Degradation of AXIN R-HSA-4641257
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
S Phase R-HSA-69242
Class I MHC mediated antigen processing & presentation R-HSA-983169
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
DNA Repair R-HSA-73894
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by NOTCH4 R-HSA-9013694
Hedgehog 'off' state R-HSA-5610787
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
ABC-family proteins mediated transport R-HSA-382556
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Nervous system development R-HSA-9675108
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
CLEC7A (Dectin-1) signaling R-HSA-5607764
Stabilization of p53 R-HSA-69541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism R-HSA-1430728
M Phase R-HSA-68886
G2/M Transition R-HSA-69275
Signaling by Hedgehog R-HSA-5358351
Axon guidance R-HSA-422475
Synthesis of DNA R-HSA-69239
ABC transporter disorders R-HSA-5619084
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of RNA R-HSA-8953854
Switching of origins to a post-replicative state R-HSA-69052
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI2 by the proteasome R-HSA-5610783
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Programmed Cell Death R-HSA-5357801
DNA Repair R-HSA-73894
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Apoptosis R-HSA-109581
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Post-translational protein modification R-HSA-597592
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular responses to stimuli R-HSA-8953897
Hh mutants abrogate ligand secretion R-HSA-5387390
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RAS by GAPs R-HSA-5658442
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
ER-Phagosome pathway R-HSA-1236974
Class I MHC mediated antigen processing & presentation R-HSA-983169
Vpu mediated degradation of CD4 R-HSA-180534
Cellular response to hypoxia R-HSA-1234174
MAPK1/MAPK3 signaling R-HSA-5684996
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Signaling by Interleukins R-HSA-449147
Degradation of AXIN R-HSA-4641257
Axon guidance R-HSA-422475
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cell Cycle R-HSA-1640170
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Mitotic G2-G2/M phases R-HSA-453274
Diseases of DNA repair R-HSA-9675135
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Disorders of transmembrane transporters R-HSA-5619115
C-type lectin receptors (CLRs) R-HSA-5621481
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCR signaling R-HSA-202403
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Metabolism of amino acids and derivatives R-HSA-71291
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog ligand biogenesis R-HSA-5358346
DNA Double-Strand Break Repair R-HSA-5693532
DNA Replication Pre-Initiation R-HSA-69002
NIK-->noncanonical NF-kB signaling R-HSA-5676590
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog 'on' state R-HSA-5632684
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
Metabolism R-HSA-1430728
Stabilization of p53 R-HSA-69541
p53-Independent DNA Damage Response R-HSA-69610
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
PTEN Regulation R-HSA-6807070
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G2/M Checkpoints R-HSA-69481
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
Assembly of the pre-replicative complex R-HSA-68867
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Neddylation R-HSA-8951664
Degradation of DVL R-HSA-4641258
Host Interactions of HIV factors R-HSA-162909
Homology Directed Repair R-HSA-5693538
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Disease R-HSA-1643685
Interleukin-1 family signaling R-HSA-446652
Signaling by Hedgehog R-HSA-5358351
G1/S Transition R-HSA-69206
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Metabolism of proteins R-HSA-392499
Signaling by NOTCH4 R-HSA-9013694
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cyclin E associated events during G1/S transition R-HSA-69202
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
UCH proteinases R-HSA-5689603
Resolution of D-Loop Structures R-HSA-5693537
Signaling by ROBO receptors R-HSA-376176
Cell Cycle Checkpoints R-HSA-69620
Signaling by WNT R-HSA-195721
Cell Cycle, Mitotic R-HSA-69278
HDR through Homologous Recombination (HRR) R-HSA-5685942
Regulation of Apoptosis R-HSA-169911
Gene expression (Transcription) R-HSA-74160
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
Immune System R-HSA-168256
Metabolism of polyamines R-HSA-351202
ABC-family proteins mediated transport R-HSA-382556
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Beta-catenin independent WNT signaling R-HSA-3858494
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FCERI mediated NF-kB activation R-HSA-2871837
Nervous system development R-HSA-9675108
Vif-mediated degradation of APOBEC3G R-HSA-180585
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
PIP3 activates AKT signaling R-HSA-1257604
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
ABC transporter disorders R-HSA-5619084
RNA Polymerase II Transcription R-HSA-73857
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by Interleukins R-HSA-449147
Regulation of RAS by GAPs R-HSA-5658442
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'on' state R-HSA-5632684
Metabolism of amino acids and derivatives R-HSA-71291
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193
Regulation of mitotic cell cycle R-HSA-453276
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Cellular response to hypoxia R-HSA-1234174
DNA Replication Pre-Initiation R-HSA-69002
G1/S DNA Damage Checkpoints R-HSA-69615
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
RNA Polymerase II Transcription R-HSA-73857
Homology Directed Repair R-HSA-5693538
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Antigen processing-Cross presentation R-HSA-1236975
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
DNA Double-Strand Break Repair R-HSA-5693532
Neddylation R-HSA-8951664
Impaired BRCA2 translocation to the nucleus R-HSA-9709275
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Repair R-HSA-73894
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of DNA Double-Strand Break Repair R-HSA-9675136
Cell Cycle Checkpoints R-HSA-69620
Ub-specific processing proteases R-HSA-5689880
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Gene expression (Transcription) R-HSA-74160
Synthesis of DNA R-HSA-69239
Degradation of GLI1 by the proteasome R-HSA-5610780
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of RNA R-HSA-8953854
Resolution of D-Loop Structures R-HSA-5693537
Signaling by NOTCH4 R-HSA-9013694
Regulation of PTEN stability and activity R-HSA-8948751
MAPK family signaling cascades R-HSA-5683057
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616
Regulation of RUNX2 expression and activity R-HSA-8939902
G1/S Transition R-HSA-69206
Hh mutants abrogate ligand secretion R-HSA-5387390
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Switching of origins to a post-replicative state R-HSA-69052
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568
Transport of small molecules R-HSA-382551
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RAF/MAP kinase cascade R-HSA-5673001
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192
Cytokine Signaling in Immune system R-HSA-1280215
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Diseases of DNA repair R-HSA-9675135
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
S Phase R-HSA-69242
Impaired BRCA2 binding to RAD51 R-HSA-9709570
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disorders of transmembrane transporters R-HSA-5619115
Apoptosis R-HSA-109581
Degradation of DVL R-HSA-4641258
Orc1 removal from chromatin R-HSA-68949
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Programmed Cell Death R-HSA-5357801
Axon guidance R-HSA-422475
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Post-translational protein modification R-HSA-597592
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by the B Cell Receptor (BCR) R-HSA-983705
M Phase R-HSA-68886
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
CLEC7A (Dectin-1) signaling R-HSA-5607764
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of AXIN R-HSA-4641257
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
HDR through Homologous Recombination (HRR) R-HSA-5685942
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
KEAP1-NFE2L2 pathway R-HSA-9755511
PCP/CE pathway R-HSA-4086400
Stabilization of p53 R-HSA-69541
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Transcriptional regulation by RUNX3 R-HSA-8878159
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
DNA Replication R-HSA-69306
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Homologous DNA Pairing and Strand Exchange R-HSA-5693579
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
ER-Phagosome pathway R-HSA-1236974
Signaling by ROBO receptors R-HSA-376176
Negative regulation of NOTCH4 signaling R-HSA-9604323
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190
TCF dependent signaling in response to WNT R-HSA-201681
Vpu mediated degradation of CD4 R-HSA-180534
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle R-HSA-1640170
Nervous system development R-HSA-9675108
Infectious disease R-HSA-5663205
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652

Expression Atlas ENSG00000127922
NCBI gene (formerly Entrezgene) 7979
GeneCards 10845
HGNC Symbol HGNC:10845
MIM gene 601285
UniProtKB Gene Name Q6ZVN7
WikiGene 7979
Gene: PTPRB
Ensembl ID : ENSG00000127329
Description: protein tyrosine phosphatase receptor type B
Gene Synonyms: PTPB
1 APIs:
268 Possible Orthologues:

Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249

Expression Atlas ENSG00000127329
NCBI gene (formerly Entrezgene) 5787
GeneCards 9665
HGNC Symbol HGNC:9665
MIM gene 176882
UniProtKB Gene Name Q6ZR19
WikiGene 5787
Gene: CA13
Ensembl ID : ENSG00000185015
Description: carbonic anhydrase 13
Gene Synonyms: CAXIII,FLJ37995,MGC59868
2 APIs:
291 Possible Orthologues:

Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029

Expression Atlas ENSG00000185015
NCBI gene (formerly Entrezgene) 377677
GeneCards 14914
HGNC Symbol HGNC:14914
MIM gene 611436
UniProtKB Gene Name Q8N1Q1
WikiGene 377677
Gene: PSMC2
Ensembl ID : ENSG00000161057
Description: proteasome 26S subunit, ATPase 2
Gene Synonyms: MSS1,NBLA10058,RPT1,S7
5 APIs:
222 Possible Orthologues:

Cell Cycle R-HSA-1640170
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
Activation of NF-kappaB in B cells R-HSA-1169091
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Gene expression (Transcription) R-HSA-74160
Vif-mediated degradation of APOBEC3G R-HSA-180585
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Cellular response to chemical stress R-HSA-9711123
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic Metaphase and Anaphase R-HSA-2555396
Neddylation R-HSA-8951664
Neutrophil degranulation R-HSA-6798695
Regulation of PTEN stability and activity R-HSA-8948751
Intracellular signaling by second messengers R-HSA-9006925
Downstream TCR signaling R-HSA-202424
M Phase R-HSA-68886
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Ub-specific processing proteases R-HSA-5689880
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'on' state R-HSA-5632684
Signal Transduction R-HSA-162582
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
DNA Replication Pre-Initiation R-HSA-69002
Hh mutants are degraded by ERAD R-HSA-5362768
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by the B Cell Receptor (BCR) R-HSA-983705
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
S Phase R-HSA-69242
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK1/MAPK3 signaling R-HSA-5684996
Vpu mediated degradation of CD4 R-HSA-180534
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
DNA Replication R-HSA-69306
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
C-type lectin receptors (CLRs) R-HSA-5621481
RNA Polymerase II Transcription R-HSA-73857
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Anaphase R-HSA-68882
Antigen processing-Cross presentation R-HSA-1236975
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
PIP3 activates AKT signaling R-HSA-1257604
Cyclin E associated events during G1/S transition R-HSA-69202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Transport of small molecules R-HSA-382551
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Metabolism of RNA R-HSA-8953854
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Axon guidance R-HSA-422475
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
Degradation of AXIN R-HSA-4641257
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of RUNX3 expression and activity R-HSA-8941858
Cell Cycle, Mitotic R-HSA-69278
Degradation of GLI1 by the proteasome R-HSA-5610780
Hedgehog 'off' state R-HSA-5610787
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ER-Phagosome pathway R-HSA-1236974
Assembly of the pre-replicative complex R-HSA-68867
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Transcriptional regulation by RUNX3 R-HSA-8878159
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RAS by GAPs R-HSA-5658442
MAPK family signaling cascades R-HSA-5683057
Class I MHC mediated antigen processing & presentation R-HSA-983169
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Metabolism of polyamines R-HSA-351202
ABC transporter disorders R-HSA-5619084
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hedgehog ligand biogenesis R-HSA-5358346
Hh mutants abrogate ligand secretion R-HSA-5387390
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Degradation of DVL R-HSA-4641258
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
PTEN Regulation R-HSA-6807070
Signaling by ROBO receptors R-HSA-376176
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Developmental Biology R-HSA-1266738
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
Metabolism of amino acids and derivatives R-HSA-71291
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RAF/MAP kinase cascade R-HSA-5673001
Regulation of Apoptosis R-HSA-169911
Switching of origins to a post-replicative state R-HSA-69052
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Nervous system development R-HSA-9675108
Synthesis of DNA R-HSA-69239
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Programmed Cell Death R-HSA-5357801
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PCP/CE pathway R-HSA-4086400
Cellular response to hypoxia R-HSA-1234174
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
MAPK family signaling cascades R-HSA-5683057
G2/M Transition R-HSA-69275
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX3 R-HSA-8878159
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MAPK1/MAPK3 signaling R-HSA-5684996
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PIP3 activates AKT signaling R-HSA-1257604
Neutrophil degranulation R-HSA-6798695
Assembly of the pre-replicative complex R-HSA-68867
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RAS by GAPs R-HSA-5658442
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
G1/S DNA Damage Checkpoints R-HSA-69615
Axon guidance R-HSA-422475
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vpu mediated degradation of CD4 R-HSA-180534
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Hh mutants abrogate ligand secretion R-HSA-5387390
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Degradation of DVL R-HSA-4641258
C-type lectin receptors (CLRs) R-HSA-5621481
Programmed Cell Death R-HSA-5357801
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by Interleukins R-HSA-449147
Ub-specific processing proteases R-HSA-5689880
CLEC7A (Dectin-1) signaling R-HSA-5607764
Nervous system development R-HSA-9675108
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Independent DNA Damage Response R-HSA-69610
Mitotic Metaphase and Anaphase R-HSA-2555396
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Infectious disease R-HSA-5663205
Metabolism of polyamines R-HSA-351202
Host Interactions of HIV factors R-HSA-162909
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Hedgehog 'on' state R-HSA-5632684
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Switching of origins to a post-replicative state R-HSA-69052
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
p53-Dependent G1 DNA Damage Response R-HSA-69563
Orc1 removal from chromatin R-HSA-68949
Gene expression (Transcription) R-HSA-74160
ER-Phagosome pathway R-HSA-1236974
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
Apoptosis R-HSA-109581
Synthesis of DNA R-HSA-69239
Mitotic G2-G2/M phases R-HSA-453274
Signal Transduction R-HSA-162582
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
Regulation of Apoptosis R-HSA-169911
ABC transporter disorders R-HSA-5619084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Developmental Biology R-HSA-1266738
Disorders of transmembrane transporters R-HSA-5619115
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Stabilization of p53 R-HSA-69541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of GLI1 by the proteasome R-HSA-5610780
DNA Replication R-HSA-69306
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
Transport of small molecules R-HSA-382551
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of amino acids and derivatives R-HSA-71291
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Metabolism of RNA R-HSA-8953854
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
Innate Immune System R-HSA-168249
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Mitotic Anaphase R-HSA-68882
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Neddylation R-HSA-8951664
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Post-translational protein modification R-HSA-597592
Cell Cycle, Mitotic R-HSA-69278
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 signaling R-HSA-9020702
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by NOTCH4 R-HSA-9013694
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stress R-HSA-2262752
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
UCH proteinases R-HSA-5689603
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RUNX2 expression and activity R-HSA-8939902
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G1/S Transition R-HSA-69206
Transcriptional regulation by RUNX2 R-HSA-8878166
DNA Replication Pre-Initiation R-HSA-69002
PCP/CE pathway R-HSA-4086400
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Mitotic G1 phase and G1/S transition R-HSA-453279
KEAP1-NFE2L2 pathway R-HSA-9755511
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
Transcriptional regulation by RUNX1 R-HSA-8878171
Signaling by WNT R-HSA-195721
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication R-HSA-69306
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RAS by GAPs R-HSA-5658442
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Separation of Sister Chromatids R-HSA-2467813
G2/M Checkpoints R-HSA-69481
Degradation of AXIN R-HSA-4641257
Interleukin-1 family signaling R-HSA-446652
Ub-specific processing proteases R-HSA-5689880
Regulation of PTEN stability and activity R-HSA-8948751
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH R-HSA-157118
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of NF-kappaB in B cells R-HSA-1169091
ABC transporter disorders R-HSA-5619084
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
MAPK6/MAPK4 signaling R-HSA-5687128
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of NOTCH4 signaling R-HSA-9604323
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by Hedgehog R-HSA-5358351
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
MAPK family signaling cascades R-HSA-5683057
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Vpu mediated degradation of CD4 R-HSA-180534
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Stabilization of p53 R-HSA-69541
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular responses to stimuli R-HSA-8953897
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Disorders of transmembrane transporters R-HSA-5619115
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Gene expression (Transcription) R-HSA-74160
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Deubiquitination R-HSA-5688426
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
ABC-family proteins mediated transport R-HSA-382556
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Cellular response to chemical stress R-HSA-9711123
Hedgehog 'off' state R-HSA-5610787
Cellular response to hypoxia R-HSA-1234174
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RAS by GAPs R-HSA-5658442
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 signaling R-HSA-9020702
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism R-HSA-1430728
Metabolism of polyamines R-HSA-351202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog ligand biogenesis R-HSA-5358346
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Interleukin-1 family signaling R-HSA-446652
Signaling by ROBO receptors R-HSA-376176
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
MAPK family signaling cascades R-HSA-5683057
Apoptosis R-HSA-109581
Hh mutants abrogate ligand secretion R-HSA-5387390
Infectious disease R-HSA-5663205
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Vpu mediated degradation of CD4 R-HSA-180534
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI2 by the proteasome R-HSA-5610783
UCH proteinases R-HSA-5689603
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
PTEN Regulation R-HSA-6807070
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Beta-catenin independent WNT signaling R-HSA-3858494
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
KEAP1-NFE2L2 pathway R-HSA-9755511
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of RUNX2 expression and activity R-HSA-8939902
Hedgehog 'on' state R-HSA-5632684
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S Transition R-HSA-69206
Post-translational protein modification R-HSA-597592
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Assembly of the pre-replicative complex R-HSA-68867
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to chemical stress R-HSA-9711123
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Downstream TCR signaling R-HSA-202424
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Programmed Cell Death R-HSA-5357801
p53-Independent DNA Damage Response R-HSA-69610
Signaling by WNT R-HSA-195721
Synthesis of DNA R-HSA-69239
ABC-family proteins mediated transport R-HSA-382556
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
TCF dependent signaling in response to WNT R-HSA-201681
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Signaling by Hedgehog R-HSA-5358351
Vif-mediated degradation of APOBEC3G R-HSA-180585
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle, Mitotic R-HSA-69278
Host Interactions of HIV factors R-HSA-162909
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Deubiquitination R-HSA-5688426
Defective CFTR causes cystic fibrosis R-HSA-5678895
PIP3 activates AKT signaling R-HSA-1257604
Mitotic Metaphase and Anaphase R-HSA-2555396
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Neutrophil degranulation R-HSA-6798695
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Antigen processing-Cross presentation R-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Metabolism of proteins R-HSA-392499
S Phase R-HSA-69242
FCERI mediated NF-kB activation R-HSA-2871837
G2/M Checkpoints R-HSA-69481
Switching of origins to a post-replicative state R-HSA-69052
Asymmetric localization of PCP proteins R-HSA-4608870
Separation of Sister Chromatids R-HSA-2467813
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
Immune System R-HSA-168256
Regulation of PTEN stability and activity R-HSA-8948751
Disorders of transmembrane transporters R-HSA-5619115
Cyclin E associated events during G1/S transition R-HSA-69202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Hh mutants are degraded by ERAD R-HSA-5362768
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Mitotic Anaphase R-HSA-68882
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Signaling by NOTCH4 R-HSA-9013694
Gene expression (Transcription) R-HSA-74160
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
ABC-family proteins mediated transport R-HSA-382556
Separation of Sister Chromatids R-HSA-2467813
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Metaphase and Anaphase R-HSA-2555396
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Disease R-HSA-1643685
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Switching of origins to a post-replicative state R-HSA-69052
MAPK family signaling cascades R-HSA-5683057
Degradation of AXIN R-HSA-4641257
Host Interactions of HIV factors R-HSA-162909
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
Neutrophil degranulation R-HSA-6798695
ABC transporter disorders R-HSA-5619084
Orc1 removal from chromatin R-HSA-68949
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
UCH proteinases R-HSA-5689603
DNA Replication R-HSA-69306
Gene expression (Transcription) R-HSA-74160
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Immune System R-HSA-168256
Cell Cycle, Mitotic R-HSA-69278
TCR signaling R-HSA-202403
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of expression of SLITs and ROBOs R-HSA-9010553
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
Mitotic Anaphase R-HSA-68882
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Infectious disease R-HSA-5663205
HIV Infection R-HSA-162906
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Downstream TCR signaling R-HSA-202424
Vpu mediated degradation of CD4 R-HSA-180534
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of RUNX3 expression and activity R-HSA-8941858
Nuclear events mediated by NFE2L2 R-HSA-9759194
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Apoptosis R-HSA-109581
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
KEAP1-NFE2L2 pathway R-HSA-9755511
G2/M Transition R-HSA-69275
Class I MHC mediated antigen processing & presentation R-HSA-983169
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
PTEN Regulation R-HSA-6807070
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of Apoptosis R-HSA-169911
Mitotic G1 phase and G1/S transition R-HSA-453279
Synthesis of DNA R-HSA-69239
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Independent DNA Damage Response R-HSA-69610
Regulation of PTEN stability and activity R-HSA-8948751
Transcriptional regulation by RUNX3 R-HSA-8878159
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by NOTCH4 R-HSA-9013694
Nervous system development R-HSA-9675108
Cell Cycle R-HSA-1640170
Cellular response to hypoxia R-HSA-1234174
Cytokine Signaling in Immune system R-HSA-1280215
Neddylation R-HSA-8951664
Developmental Biology R-HSA-1266738
Assembly of the pre-replicative complex R-HSA-68867
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RAS by GAPs R-HSA-5658442
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX2 expression and activity R-HSA-8939902
FCERI mediated NF-kB activation R-HSA-2871837
Axon guidance R-HSA-422475
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
PIP3 activates AKT signaling R-HSA-1257604
Disorders of transmembrane transporters R-HSA-5619115
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
M Phase R-HSA-68886
Cyclin E associated events during G1/S transition R-HSA-69202
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular response to chemical stress R-HSA-9711123
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Transport of small molecules R-HSA-382551
Signaling by ROBO receptors R-HSA-376176
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Transcriptional regulation by RUNX2 R-HSA-8878166
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Innate Immune System R-HSA-168249
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
Deubiquitination R-HSA-5688426
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Mitotic G2-G2/M phases R-HSA-453274
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Disorders of transmembrane transporters R-HSA-5619115
Transport of small molecules R-HSA-382551
Degradation of AXIN R-HSA-4641257
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism R-HSA-1430728
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Intracellular signaling by second messengers R-HSA-9006925
S Phase R-HSA-69242
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Downstream TCR signaling R-HSA-202424
Metabolism of RNA R-HSA-8953854
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of polyamines R-HSA-351202
Programmed Cell Death R-HSA-5357801
Asymmetric localization of PCP proteins R-HSA-4608870
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
HIV Infection R-HSA-162906
Degradation of beta-catenin by the destruction complex R-HSA-195253
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX3 expression and activity R-HSA-8941858
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Signaling by NOTCH R-HSA-157118
RAF/MAP kinase cascade R-HSA-5673001
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
PTEN Regulation R-HSA-6807070
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Generic Transcription Pathway R-HSA-212436
Mitotic Anaphase R-HSA-68882
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Post-translational protein modification R-HSA-597592
Transcriptional regulation by RUNX1 R-HSA-8878171
Cellular responses to stress R-HSA-2262752
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
M Phase R-HSA-68886
RNA Polymerase II Transcription R-HSA-73857
Regulation of mitotic cell cycle R-HSA-453276
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Hedgehog R-HSA-5358351
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Apoptosis R-HSA-109581
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX2 expression and activity R-HSA-8939902
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication Pre-Initiation R-HSA-69002
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of GLI1 by the proteasome R-HSA-5610780
PCP/CE pathway R-HSA-4086400
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of proteins R-HSA-392499
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Immune System R-HSA-168256
Mitotic G1 phase and G1/S transition R-HSA-453279
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'off' state R-HSA-5610787
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
ER-Phagosome pathway R-HSA-1236974
UCH proteinases R-HSA-5689603
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Neutrophil degranulation R-HSA-6798695
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
Cellular response to chemical stress R-HSA-9711123
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Class I MHC mediated antigen processing & presentation R-HSA-983169
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
G2/M Transition R-HSA-69275
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cell Cycle R-HSA-1640170
Hedgehog 'on' state R-HSA-5632684
Neddylation R-HSA-8951664
Adaptive Immune System R-HSA-1280218
KEAP1-NFE2L2 pathway R-HSA-9755511
PIP3 activates AKT signaling R-HSA-1257604
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Degradation of GLI2 by the proteasome R-HSA-5610783
Assembly of the pre-replicative complex R-HSA-68867
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Signaling by NOTCH4 R-HSA-9013694
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
ER-Phagosome pathway R-HSA-1236974
Stabilization of p53 R-HSA-69541
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stress R-HSA-2262752
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PTEN Regulation R-HSA-6807070
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Infectious disease R-HSA-5663205
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
Programmed Cell Death R-HSA-5357801
UCH proteinases R-HSA-5689603
Disease R-HSA-1643685
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Signaling by NOTCH4 R-HSA-9013694
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
KEAP1-NFE2L2 pathway R-HSA-9755511
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G2/M Transition R-HSA-69275
Neddylation R-HSA-8951664
PCP/CE pathway R-HSA-4086400
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI1 by the proteasome R-HSA-5610780
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Mitotic G1 phase and G1/S transition R-HSA-453279
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
MAPK family signaling cascades R-HSA-5683057
S Phase R-HSA-69242
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mitotic cell cycle R-HSA-453276
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Neutrophil degranulation R-HSA-6798695
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Degradation of beta-catenin by the destruction complex R-HSA-195253
Nervous system development R-HSA-9675108
Immune System R-HSA-168256
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Downstream TCR signaling R-HSA-202424
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Hh mutants abrogate ligand secretion R-HSA-5387390
Transcriptional regulation by RUNX2 R-HSA-8878166
CLEC7A (Dectin-1) signaling R-HSA-5607764
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
TCR signaling R-HSA-202403
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of PTEN stability and activity R-HSA-8948751
Asymmetric localization of PCP proteins R-HSA-4608870
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
Hedgehog 'off' state R-HSA-5610787
ABC transporter disorders R-HSA-5619084
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Separation of Sister Chromatids R-HSA-2467813
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transport of small molecules R-HSA-382551
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of RAS by GAPs R-HSA-5658442
Hedgehog 'on' state R-HSA-5632684
Disorders of transmembrane transporters R-HSA-5619115
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Orc1 removal from chromatin R-HSA-68949
Post-translational protein modification R-HSA-597592
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
RNA Polymerase II Transcription R-HSA-73857
Developmental Biology R-HSA-1266738
Cellular responses to stimuli R-HSA-8953897
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of Apoptosis R-HSA-169911
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Assembly of the pre-replicative complex R-HSA-68867
MAPK6/MAPK4 signaling R-HSA-5687128
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
Metabolism of RNA R-HSA-8953854
DNA Replication Pre-Initiation R-HSA-69002
Switching of origins to a post-replicative state R-HSA-69052
Signaling by NOTCH R-HSA-157118
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of GLI2 by the proteasome R-HSA-5610783
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of RUNX2 expression and activity R-HSA-8939902
Signal Transduction R-HSA-162582
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by ROBO receptors R-HSA-376176
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
DNA Replication R-HSA-69306
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
G1/S DNA Damage Checkpoints R-HSA-69615
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TCF dependent signaling in response to WNT R-HSA-201681
Interleukin-1 family signaling R-HSA-446652
Mitotic Anaphase R-HSA-68882
TCR signaling R-HSA-202403
Signaling by NOTCH4 R-HSA-9013694
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants are degraded by ERAD R-HSA-5362768
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
MAPK6/MAPK4 signaling R-HSA-5687128
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stimuli R-HSA-8953897
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Transport of small molecules R-HSA-382551
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
M Phase R-HSA-68886
Deubiquitination R-HSA-5688426
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'off' state R-HSA-5610787
ABC-family proteins mediated transport R-HSA-382556
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of PTEN stability and activity R-HSA-8948751
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Signaling by Hedgehog R-HSA-5358351
PTEN Regulation R-HSA-6807070
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of RNA R-HSA-8953854
Degradation of AXIN R-HSA-4641257
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Transcriptional regulation by RUNX2 R-HSA-8878166
Vpu mediated degradation of CD4 R-HSA-180534
Disorders of transmembrane transporters R-HSA-5619115
Gene expression (Transcription) R-HSA-74160
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Generic Transcription Pathway R-HSA-212436
Neddylation R-HSA-8951664
RNA Polymerase II Transcription R-HSA-73857
Degradation of GLI2 by the proteasome R-HSA-5610783
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
Ub-specific processing proteases R-HSA-5689880
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
G2/M Checkpoints R-HSA-69481
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Metaphase and Anaphase R-HSA-2555396
Assembly of the pre-replicative complex R-HSA-68867
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
NIK-->noncanonical NF-kB signaling R-HSA-5676590
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cell Cycle, Mitotic R-HSA-69278
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
UCH proteinases R-HSA-5689603
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 signaling R-HSA-9020702
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by WNT R-HSA-195721
Defective CFTR causes cystic fibrosis R-HSA-5678895
G2/M Transition R-HSA-69275
Degradation of DVL R-HSA-4641258
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Mitotic G2-G2/M phases R-HSA-453274
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
Neutrophil degranulation R-HSA-6798695
Metabolism of proteins R-HSA-392499
Signaling by ROBO receptors R-HSA-376176
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Axon guidance R-HSA-422475
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
G1/S DNA Damage Checkpoints R-HSA-69615
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism R-HSA-1430728
Nervous system development R-HSA-9675108
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle R-HSA-1640170
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
HIV Infection R-HSA-162906
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Stabilization of p53 R-HSA-69541
Metabolism of polyamines R-HSA-351202
Signal Transduction R-HSA-162582
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
PCP/CE pathway R-HSA-4086400
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S Transition R-HSA-69206
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
DNA Replication Pre-Initiation R-HSA-69002
Developmental Biology R-HSA-1266738
Apoptosis R-HSA-109581
Negative regulation of NOTCH4 signaling R-HSA-9604323
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
MAPK1/MAPK3 signaling R-HSA-5684996
Infectious disease R-HSA-5663205
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
G1/S DNA Damage Checkpoints R-HSA-69615
Antigen processing-Cross presentation R-HSA-1236975
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
DNA Replication R-HSA-69306
Transcriptional regulation by RUNX3 R-HSA-8878159
Disorders of transmembrane transporters R-HSA-5619115
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Synthesis of DNA R-HSA-69239
Cellular responses to stress R-HSA-2262752
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Neddylation R-HSA-8951664
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Cytokine Signaling in Immune system R-HSA-1280215
Degradation of GLI1 by the proteasome R-HSA-5610780
Cell Cycle, Mitotic R-HSA-69278
Degradation of DVL R-HSA-4641258
Signaling by WNT R-HSA-195721
Signaling by ROBO receptors R-HSA-376176
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
ER-Phagosome pathway R-HSA-1236974
Downstream TCR signaling R-HSA-202424
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Metabolism of amino acids and derivatives R-HSA-71291
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
KEAP1-NFE2L2 pathway R-HSA-9755511
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MAPK1/MAPK3 signaling R-HSA-5684996
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
Separation of Sister Chromatids R-HSA-2467813
Activation of NF-kappaB in B cells R-HSA-1169091
Programmed Cell Death R-HSA-5357801
Degradation of GLI2 by the proteasome R-HSA-5610783
Innate Immune System R-HSA-168249
Hedgehog ligand biogenesis R-HSA-5358346
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 signaling R-HSA-9020702
Cell Cycle R-HSA-1640170
HIV Infection R-HSA-162906
Mitotic G2-G2/M phases R-HSA-453274
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
FCERI mediated NF-kB activation R-HSA-2871837
Developmental Biology R-HSA-1266738
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
S Phase R-HSA-69242
PTEN Regulation R-HSA-6807070
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Metabolism of proteins R-HSA-392499
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Apoptosis R-HSA-109581
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Orc1 removal from chromatin R-HSA-68949
Axon guidance R-HSA-422475
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
ABC-family proteins mediated transport R-HSA-382556
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular responses to stimuli R-HSA-8953897
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of RNA R-HSA-8953854
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
p53-Independent DNA Damage Response R-HSA-69610
Cyclin E associated events during G1/S transition R-HSA-69202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Degradation of beta-catenin by the destruction complex R-HSA-195253
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
Neutrophil degranulation R-HSA-6798695
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Host Interactions of HIV factors R-HSA-162909
Defective CFTR causes cystic fibrosis R-HSA-5678895
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
Regulation of RUNX2 expression and activity R-HSA-8939902
ABC transporter disorders R-HSA-5619084
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
C-type lectin receptors (CLRs) R-HSA-5621481
Transport of small molecules R-HSA-382551
MAPK family signaling cascades R-HSA-5683057
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to hypoxia R-HSA-1234174
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of Apoptosis R-HSA-169911
Disease R-HSA-1643685
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
CLEC7A (Dectin-1) signaling R-HSA-5607764
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by NOTCH4 R-HSA-9013694
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Post-translational protein modification R-HSA-597592
Cell Cycle Checkpoints R-HSA-69620
Assembly of the pre-replicative complex R-HSA-68867
Hedgehog 'off' state R-HSA-5610787
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
p53-Dependent G1 DNA Damage Response R-HSA-69563
MAPK family signaling cascades R-HSA-5683057
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Neutrophil degranulation R-HSA-6798695
Cell Cycle, Mitotic R-HSA-69278
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
Assembly of the pre-replicative complex R-HSA-68867
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
M Phase R-HSA-68886
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of mitotic cell cycle R-HSA-453276
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ROBO receptors R-HSA-376176
Host Interactions of HIV factors R-HSA-162909
Ub-specific processing proteases R-HSA-5689880
Vif-mediated degradation of APOBEC3G R-HSA-180585
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Degradation of beta-catenin by the destruction complex R-HSA-195253
Immune System R-HSA-168256
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
Hedgehog 'on' state R-HSA-5632684
TCF dependent signaling in response to WNT R-HSA-201681
Synthesis of DNA R-HSA-69239
UCH proteinases R-HSA-5689603
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH R-HSA-157118
FCERI mediated NF-kB activation R-HSA-2871837
PTEN Regulation R-HSA-6807070
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of AXIN R-HSA-4641257
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Class I MHC mediated antigen processing & presentation R-HSA-983169
C-type lectin receptors (CLRs) R-HSA-5621481
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to chemical stress R-HSA-9711123
Cell Cycle Checkpoints R-HSA-69620
Antigen processing-Cross presentation R-HSA-1236975
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Separation of Sister Chromatids R-HSA-2467813
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Innate Immune System R-HSA-168249
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
RAF/MAP kinase cascade R-HSA-5673001
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Generic Transcription Pathway R-HSA-212436
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle R-HSA-1640170
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of DVL R-HSA-4641258
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Signaling by NOTCH4 R-HSA-9013694
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Post-translational protein modification R-HSA-597592
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
Axon guidance R-HSA-422475
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Stabilization of p53 R-HSA-69541
Neddylation R-HSA-8951664
Regulation of RUNX3 expression and activity R-HSA-8941858
Defective CFTR causes cystic fibrosis R-HSA-5678895
KEAP1-NFE2L2 pathway R-HSA-9755511
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of RUNX2 expression and activity R-HSA-8939902
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Signaling by Hedgehog R-HSA-5358351
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transport of small molecules R-HSA-382551
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S Transition R-HSA-69206
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of PTEN stability and activity R-HSA-8948751
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
DNA Replication Pre-Initiation R-HSA-69002
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Programmed Cell Death R-HSA-5357801
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of Apoptosis R-HSA-169911
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX3 R-HSA-8878159
Interleukin-1 family signaling R-HSA-446652
MAPK family signaling cascades R-HSA-5683057
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Assembly of the pre-replicative complex R-HSA-68867
Mitotic G1 phase and G1/S transition R-HSA-453279
Post-translational protein modification R-HSA-597592
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
UCH proteinases R-HSA-5689603
Signal Transduction R-HSA-162582
FCERI mediated NF-kB activation R-HSA-2871837
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Antigen processing-Cross presentation R-HSA-1236975
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Deubiquitination R-HSA-5688426
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Separation of Sister Chromatids R-HSA-2467813
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Signaling by NOTCH4 R-HSA-9013694
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cell Cycle Checkpoints R-HSA-69620
PCP/CE pathway R-HSA-4086400
Metabolism of proteins R-HSA-392499
Regulation of RAS by GAPs R-HSA-5658442
Host Interactions of HIV factors R-HSA-162909
Switching of origins to a post-replicative state R-HSA-69052
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
Nuclear events mediated by NFE2L2 R-HSA-9759194
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
Degradation of AXIN R-HSA-4641257
Hedgehog ligand biogenesis R-HSA-5358346
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
Immune System R-HSA-168256
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G2-G2/M phases R-HSA-453274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to hypoxia R-HSA-1234174
Metabolism of RNA R-HSA-8953854
Signaling by WNT R-HSA-195721
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Activation of NF-kappaB in B cells R-HSA-1169091
Transport of small molecules R-HSA-382551
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Disorders of transmembrane transporters R-HSA-5619115
ABC-family proteins mediated transport R-HSA-382556
HIV Infection R-HSA-162906
Adaptive Immune System R-HSA-1280218
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Anaphase R-HSA-68882
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Interleukin-1 signaling R-HSA-9020702
Metabolism R-HSA-1430728
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G1/S Transition R-HSA-69206
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
p53-Independent DNA Damage Response R-HSA-69610
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
C-type lectin receptors (CLRs) R-HSA-5621481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
Neutrophil degranulation R-HSA-6798695
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Infectious disease R-HSA-5663205
Neddylation R-HSA-8951664
Signaling by Hedgehog R-HSA-5358351
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mitotic cell cycle R-HSA-453276
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Class I MHC mediated antigen processing & presentation R-HSA-983169
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cytokine Signaling in Immune system R-HSA-1280215
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Axon guidance R-HSA-422475
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
G2/M Checkpoints R-HSA-69481
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Intracellular signaling by second messengers R-HSA-9006925
Disease R-HSA-1643685
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of polyamines R-HSA-351202
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'on' state R-HSA-5632684

Expression Atlas ENSG00000161057
NCBI gene (formerly Entrezgene) 5701
GeneCards 9548
HGNC Symbol HGNC:9548
MIM gene 154365
UniProtKB Gene Name P35998
WikiGene 5701