Gene: PSMB4
Ensembl ID : ENSG00000159377
Description: proteasome 20S subunit beta 4
Gene Synonyms: HN3,PROS26
6 APIs:
214 Possible Orthologues:

UCH proteinases R-HSA-5689603
Assembly of the pre-replicative complex R-HSA-68867
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
G1/S Transition R-HSA-69206
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by WNT R-HSA-195721
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
Cellular response to chemical stress R-HSA-9711123
Negative regulation of NOTCH4 signaling R-HSA-9604323
TCR signaling R-HSA-202403
Separation of Sister Chromatids R-HSA-2467813
TCF dependent signaling in response to WNT R-HSA-201681
Metabolism of RNA R-HSA-8953854
C-type lectin receptors (CLRs) R-HSA-5621481
Degradation of AXIN R-HSA-4641257
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
ER-Phagosome pathway R-HSA-1236974
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism of polyamines R-HSA-351202
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Nervous system development R-HSA-9675108
Generic Transcription Pathway R-HSA-212436
M Phase R-HSA-68886
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle R-HSA-1640170
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Host Interactions of HIV factors R-HSA-162909
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of amino acids and derivatives R-HSA-71291
Hedgehog 'on' state R-HSA-5632684
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cellular response to hypoxia R-HSA-1234174
Disease R-HSA-1643685
Mitotic G1 phase and G1/S transition R-HSA-453279
Intracellular signaling by second messengers R-HSA-9006925
Interleukin-1 family signaling R-HSA-446652
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
Cytokine Signaling in Immune system R-HSA-1280215
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hedgehog 'off' state R-HSA-5610787
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
G2/M Transition R-HSA-69275
Vif-mediated degradation of APOBEC3G R-HSA-180585
Vpu mediated degradation of CD4 R-HSA-180534
Interleukin-1 signaling R-HSA-9020702
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Developmental Biology R-HSA-1266738
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Antigen processing-Cross presentation R-HSA-1236975
Mitotic G2-G2/M phases R-HSA-453274
S Phase R-HSA-69242
Transport of small molecules R-HSA-382551
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by NOTCH4 R-HSA-9013694
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
G2/M Checkpoints R-HSA-69481
Adaptive Immune System R-HSA-1280218
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of Apoptosis R-HSA-169911
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
KEAP1-NFE2L2 pathway R-HSA-9755511
Hh mutants are degraded by ERAD R-HSA-5362768
Beta-catenin independent WNT signaling R-HSA-3858494
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Asymmetric localization of PCP proteins R-HSA-4608870
Gene expression (Transcription) R-HSA-74160
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Independent DNA Damage Response R-HSA-69610
Orc1 removal from chromatin R-HSA-68949
RAF/MAP kinase cascade R-HSA-5673001
PTEN Regulation R-HSA-6807070
Regulation of mitotic cell cycle R-HSA-453276
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Metabolism of proteins R-HSA-392499
Cellular responses to stress R-HSA-2262752
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
Ub-specific processing proteases R-HSA-5689880
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
DNA Replication R-HSA-69306
PCP/CE pathway R-HSA-4086400
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Apoptosis R-HSA-109581
Axon guidance R-HSA-422475
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of DVL R-HSA-4641258
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by NOTCH R-HSA-157118
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by ROBO receptors R-HSA-376176
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
HIV Infection R-HSA-162906
Neddylation R-HSA-8951664
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Mitotic Metaphase and Anaphase R-HSA-2555396
CLEC7A (Dectin-1) signaling R-HSA-5607764
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Signaling by Hedgehog R-HSA-5358351
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication Pre-Initiation R-HSA-69002
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog 'off' state R-HSA-5610787
Hh mutants are degraded by ERAD R-HSA-5362768
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
p53-Independent DNA Damage Response R-HSA-69610
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Generic Transcription Pathway R-HSA-212436
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Degradation of GLI1 by the proteasome R-HSA-5610780
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of PTEN stability and activity R-HSA-8948751
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism R-HSA-1430728
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Transcriptional regulation by RUNX2 R-HSA-8878166
Cell Cycle, Mitotic R-HSA-69278
Degradation of AXIN R-HSA-4641257
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
Hh mutants abrogate ligand secretion R-HSA-5387390
Orc1 removal from chromatin R-HSA-68949
Nervous system development R-HSA-9675108
Apoptosis R-HSA-109581
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC transporter disorders R-HSA-5619084
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
M Phase R-HSA-68886
S Phase R-HSA-69242
Synthesis of DNA R-HSA-69239
RAF/MAP kinase cascade R-HSA-5673001
Developmental Biology R-HSA-1266738
Transcriptional regulation by RUNX1 R-HSA-8878171
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Hedgehog 'on' state R-HSA-5632684
Cyclin E associated events during G1/S transition R-HSA-69202
Downstream TCR signaling R-HSA-202424
G2/M Checkpoints R-HSA-69481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Assembly of the pre-replicative complex R-HSA-68867
Host Interactions of HIV factors R-HSA-162909
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
HIV Infection R-HSA-162906
FCERI mediated NF-kB activation R-HSA-2871837
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Neddylation R-HSA-8951664
Intracellular signaling by second messengers R-HSA-9006925
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism of RNA R-HSA-8953854
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
TCR signaling R-HSA-202403
Regulation of RAS by GAPs R-HSA-5658442
Infectious disease R-HSA-5663205
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
C-type lectin receptors (CLRs) R-HSA-5621481
PIP3 activates AKT signaling R-HSA-1257604
Mitotic G2-G2/M phases R-HSA-453274
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Immune System R-HSA-168256
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
TCF dependent signaling in response to WNT R-HSA-201681
MAPK family signaling cascades R-HSA-5683057
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of proteins R-HSA-392499
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transport of small molecules R-HSA-382551
Metabolism of polyamines R-HSA-351202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Switching of origins to a post-replicative state R-HSA-69052
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by WNT R-HSA-195721
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing-Cross presentation R-HSA-1236975
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Disease R-HSA-1643685
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by NOTCH4 R-HSA-9013694
KEAP1-NFE2L2 pathway R-HSA-9755511
Cell Cycle R-HSA-1640170
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of Apoptosis R-HSA-169911
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle Checkpoints R-HSA-69620
Transcriptional regulation by RUNX3 R-HSA-8878159
ABC-family proteins mediated transport R-HSA-382556
Interleukin-1 signaling R-HSA-9020702
ER-Phagosome pathway R-HSA-1236974
PTEN Regulation R-HSA-6807070
Innate Immune System R-HSA-168249
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK1/MAPK3 signaling R-HSA-5684996
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Vif-mediated degradation of APOBEC3G R-HSA-180585
Interleukin-1 family signaling R-HSA-446652
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cyclin E associated events during G1/S transition R-HSA-69202
Class I MHC mediated antigen processing & presentation R-HSA-983169
RAF/MAP kinase cascade R-HSA-5673001
Host Interactions of HIV factors R-HSA-162909
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
S Phase R-HSA-69242
TCF dependent signaling in response to WNT R-HSA-201681
G2/M Transition R-HSA-69275
Hedgehog 'on' state R-HSA-5632684
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Vpu mediated degradation of CD4 R-HSA-180534
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signal Transduction R-HSA-162582
Cell Cycle, Mitotic R-HSA-69278
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Vif-mediated degradation of APOBEC3G R-HSA-180585
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Beta-catenin independent WNT signaling R-HSA-3858494
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of amino acids and derivatives R-HSA-71291
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI1 by the proteasome R-HSA-5610780
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of expression of SLITs and ROBOs R-HSA-9010553
KEAP1-NFE2L2 pathway R-HSA-9755511
Disease R-HSA-1643685
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
Degradation of DVL R-HSA-4641258
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PIP3 activates AKT signaling R-HSA-1257604
Deubiquitination R-HSA-5688426
Transcriptional regulation by RUNX1 R-HSA-8878171
Mitotic Anaphase R-HSA-68882
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cytokine Signaling in Immune system R-HSA-1280215
Synthesis of DNA R-HSA-69239
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Asymmetric localization of PCP proteins R-HSA-4608870
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
M Phase R-HSA-68886
Metabolism of polyamines R-HSA-351202
Regulation of RUNX3 expression and activity R-HSA-8941858
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Cellular response to hypoxia R-HSA-1234174
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of proteins R-HSA-392499
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Interleukin-1 family signaling R-HSA-446652
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle R-HSA-1640170
Metabolism R-HSA-1430728
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle Checkpoints R-HSA-69620
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
RNA Polymerase II Transcription R-HSA-73857
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by WNT R-HSA-195721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
G2/M Checkpoints R-HSA-69481
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Signaling by ROBO receptors R-HSA-376176
Regulation of RAS by GAPs R-HSA-5658442
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
HIV Infection R-HSA-162906
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Infectious disease R-HSA-5663205
Nervous system development R-HSA-9675108
ABC transporter disorders R-HSA-5619084
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of mitotic cell cycle R-HSA-453276
Hedgehog ligand biogenesis R-HSA-5358346
Degradation of AXIN R-HSA-4641257
Hh mutants are degraded by ERAD R-HSA-5362768
Immune System R-HSA-168256
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing-Cross presentation R-HSA-1236975
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Metabolism of RNA R-HSA-8953854
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
PCP/CE pathway R-HSA-4086400
Regulation of PTEN stability and activity R-HSA-8948751
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Innate Immune System R-HSA-168249
TCR signaling R-HSA-202403
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Hedgehog 'off' state R-HSA-5610787
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by Hedgehog R-HSA-5358351
CLEC7A (Dectin-1) signaling R-HSA-5607764
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
ER-Phagosome pathway R-HSA-1236974
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of Apoptosis R-HSA-169911
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mitotic cell cycle R-HSA-453276
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Cellular responses to stimuli R-HSA-8953897
Degradation of beta-catenin by the destruction complex R-HSA-195253
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of RUNX2 expression and activity R-HSA-8939902
Cellular response to hypoxia R-HSA-1234174
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
KEAP1-NFE2L2 pathway R-HSA-9755511
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Dependent G1 DNA Damage Response R-HSA-69563
Intracellular signaling by second messengers R-HSA-9006925
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
S Phase R-HSA-69242
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Ub-specific processing proteases R-HSA-5689880
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Immune System R-HSA-168256
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH R-HSA-157118
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Signaling by WNT R-HSA-195721
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by NOTCH4 R-HSA-9013694
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK family signaling cascades R-HSA-5683057
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of DVL R-HSA-4641258
G2/M Transition R-HSA-69275
CLEC7A (Dectin-1) signaling R-HSA-5607764
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Programmed Cell Death R-HSA-5357801
Interleukin-1 family signaling R-HSA-446652
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cell Cycle Checkpoints R-HSA-69620
Signaling by ROBO receptors R-HSA-376176
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Interleukin-1 signaling R-HSA-9020702
Generic Transcription Pathway R-HSA-212436
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog ligand biogenesis R-HSA-5358346
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of PTEN stability and activity R-HSA-8948751
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Anaphase R-HSA-68882
Neddylation R-HSA-8951664
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX2 R-HSA-8878166
Axon guidance R-HSA-422475
PTEN Regulation R-HSA-6807070
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Vif-mediated degradation of APOBEC3G R-HSA-180585
Asymmetric localization of PCP proteins R-HSA-4608870
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nervous system development R-HSA-9675108
Antigen processing-Cross presentation R-HSA-1236975
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Vpu mediated degradation of CD4 R-HSA-180534
Negative regulation of NOTCH4 signaling R-HSA-9604323
C-type lectin receptors (CLRs) R-HSA-5621481
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Beta-catenin independent WNT signaling R-HSA-3858494
ABC-family proteins mediated transport R-HSA-382556
Transport of small molecules R-HSA-382551
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication R-HSA-69306
Nuclear events mediated by NFE2L2 R-HSA-9759194
ABC transporter disorders R-HSA-5619084
MAPK1/MAPK3 signaling R-HSA-5684996
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Interleukins R-HSA-449147
Deubiquitination R-HSA-5688426
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cyclin E associated events during G1/S transition R-HSA-69202
Orc1 removal from chromatin R-HSA-68949
DNA Replication Pre-Initiation R-HSA-69002
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
PCP/CE pathway R-HSA-4086400
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of proteins R-HSA-392499
Degradation of AXIN R-HSA-4641257
Mitotic Metaphase and Anaphase R-HSA-2555396
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Stabilization of p53 R-HSA-69541
Hedgehog 'on' state R-HSA-5632684
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
RAF/MAP kinase cascade R-HSA-5673001
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Degradation of GLI2 by the proteasome R-HSA-5610783
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Independent DNA Damage Response R-HSA-69610
UCH proteinases R-HSA-5689603
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of RUNX2 expression and activity R-HSA-8939902
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of AXIN R-HSA-4641257
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Mitotic Anaphase R-HSA-68882
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
UCH proteinases R-HSA-5689603
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
M Phase R-HSA-68886
PCP/CE pathway R-HSA-4086400
C-type lectin receptors (CLRs) R-HSA-5621481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Hedgehog 'on' state R-HSA-5632684
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Cell Cycle, Mitotic R-HSA-69278
G2/M Transition R-HSA-69275
Mitotic G2-G2/M phases R-HSA-453274
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of beta-catenin by the destruction complex R-HSA-195253
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX1 R-HSA-8878171
Transport of small molecules R-HSA-382551
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RAS by GAPs R-HSA-5658442
Mitotic Metaphase and Anaphase R-HSA-2555396
Infectious disease R-HSA-5663205
Gene expression (Transcription) R-HSA-74160
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Programmed Cell Death R-HSA-5357801
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to hypoxia R-HSA-1234174
Hedgehog 'off' state R-HSA-5610787
Signaling by NOTCH R-HSA-157118
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
Asymmetric localization of PCP proteins R-HSA-4608870
Adaptive Immune System R-HSA-1280218
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Deubiquitination R-HSA-5688426
Ub-specific processing proteases R-HSA-5689880
Signaling by NOTCH4 R-HSA-9013694
CLEC7A (Dectin-1) signaling R-HSA-5607764
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog ligand biogenesis R-HSA-5358346
HIV Infection R-HSA-162906
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
S Phase R-HSA-69242
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signaling by WNT R-HSA-195721
Metabolism of proteins R-HSA-392499
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular responses to stimuli R-HSA-8953897
Axon guidance R-HSA-422475
Mitotic G1 phase and G1/S transition R-HSA-453279
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of mitotic cell cycle R-HSA-453276
Class I MHC mediated antigen processing & presentation R-HSA-983169
Nervous system development R-HSA-9675108
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Immune System R-HSA-168256
Signaling by ROBO receptors R-HSA-376176
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of DVL R-HSA-4641258
Neddylation R-HSA-8951664
Host Interactions of HIV factors R-HSA-162909
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Independent DNA Damage Response R-HSA-69610
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Vpu mediated degradation of CD4 R-HSA-180534
Stabilization of p53 R-HSA-69541
Assembly of the pre-replicative complex R-HSA-68867
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Downstream TCR signaling R-HSA-202424
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signal Transduction R-HSA-162582
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Transcriptional regulation by RUNX3 R-HSA-8878159
RAF/MAP kinase cascade R-HSA-5673001
Defective CFTR causes cystic fibrosis R-HSA-5678895
Disease R-HSA-1643685
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
ER-Phagosome pathway R-HSA-1236974
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Transcriptional regulation by RUNX2 R-HSA-8878166
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of polyamines R-HSA-351202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
PTEN Regulation R-HSA-6807070
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
ABC transporter disorders R-HSA-5619084
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
TCF dependent signaling in response to WNT R-HSA-201681
TCR signaling R-HSA-202403
Signaling by Hedgehog R-HSA-5358351
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Interleukin-1 family signaling R-HSA-446652
Disorders of transmembrane transporters R-HSA-5619115
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Transcriptional regulation by RUNX1 R-HSA-8878171
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Gene expression (Transcription) R-HSA-74160
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Apoptosis R-HSA-109581
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK6/MAPK4 signaling R-HSA-5687128
Interleukin-1 signaling R-HSA-9020702
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
PIP3 activates AKT signaling R-HSA-1257604
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by Interleukins R-HSA-449147
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of AXIN R-HSA-4641257
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by NOTCH4 R-HSA-9013694
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Hh mutants are degraded by ERAD R-HSA-5362768
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
G2/M Checkpoints R-HSA-69481
Transcriptional regulation by RUNX2 R-HSA-8878166
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Metabolism R-HSA-1430728
Nuclear events mediated by NFE2L2 R-HSA-9759194
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Defective CFTR causes cystic fibrosis R-HSA-5678895
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Class I MHC mediated antigen processing & presentation R-HSA-983169
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PCP/CE pathway R-HSA-4086400
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stimuli R-HSA-8953897
Mitotic Anaphase R-HSA-68882
Host Interactions of HIV factors R-HSA-162909
Metabolism of polyamines R-HSA-351202
RAF/MAP kinase cascade R-HSA-5673001
Neddylation R-HSA-8951664
C-type lectin receptors (CLRs) R-HSA-5621481
Axon guidance R-HSA-422475
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
TCR signaling R-HSA-202403
Regulation of mitotic cell cycle R-HSA-453276
Cytokine Signaling in Immune system R-HSA-1280215
RNA Polymerase II Transcription R-HSA-73857
Beta-catenin independent WNT signaling R-HSA-3858494
Hedgehog 'off' state R-HSA-5610787
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Transport of small molecules R-HSA-382551
Nervous system development R-HSA-9675108
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Programmed Cell Death R-HSA-5357801
Degradation of DVL R-HSA-4641258
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Metabolism of amino acids and derivatives R-HSA-71291
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
Regulation of RUNX2 expression and activity R-HSA-8939902
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
G1/S DNA Damage Checkpoints R-HSA-69615
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Immune System R-HSA-168256
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
FCERI mediated NF-kB activation R-HSA-2871837
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of proteins R-HSA-392499
Hedgehog 'on' state R-HSA-5632684
Post-translational protein modification R-HSA-597592
Regulation of PTEN stability and activity R-HSA-8948751
G2/M Transition R-HSA-69275
TCF dependent signaling in response to WNT R-HSA-201681
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Antigen processing-Cross presentation R-HSA-1236975
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
ABC-family proteins mediated transport R-HSA-382556
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular response to chemical stress R-HSA-9711123
Regulation of RAS by GAPs R-HSA-5658442
UCH proteinases R-HSA-5689603
G1/S Transition R-HSA-69206
Signal Transduction R-HSA-162582
Asymmetric localization of PCP proteins R-HSA-4608870
Interleukin-1 family signaling R-HSA-446652
Separation of Sister Chromatids R-HSA-2467813
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Degradation of GLI2 by the proteasome R-HSA-5610783
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Metabolism of RNA R-HSA-8953854
ER-Phagosome pathway R-HSA-1236974
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G1 phase and G1/S transition R-HSA-453279
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Downstream TCR signaling R-HSA-202424
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
RNA Polymerase II Transcription R-HSA-73857
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Mitotic Metaphase and Anaphase R-HSA-2555396
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent DNA Damage Response R-HSA-69610
Antigen processing-Cross presentation R-HSA-1236975
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
ABC-family proteins mediated transport R-HSA-382556
Disorders of transmembrane transporters R-HSA-5619115
Ub-specific processing proteases R-HSA-5689880
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Regulation of mitotic cell cycle R-HSA-453276
Immune System R-HSA-168256
MAPK family signaling cascades R-HSA-5683057
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hh mutants abrogate ligand secretion R-HSA-5387390
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cyclin E associated events during G1/S transition R-HSA-69202
Hedgehog ligand biogenesis R-HSA-5358346
Neddylation R-HSA-8951664
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
Cellular responses to stimuli R-HSA-8953897
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
MAPK1/MAPK3 signaling R-HSA-5684996
ER-Phagosome pathway R-HSA-1236974
Beta-catenin independent WNT signaling R-HSA-3858494
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
PIP3 activates AKT signaling R-HSA-1257604
HIV Infection R-HSA-162906
Signaling by WNT R-HSA-195721
G2/M Checkpoints R-HSA-69481
MAPK6/MAPK4 signaling R-HSA-5687128
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Disease R-HSA-1643685
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of Apoptosis R-HSA-169911
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Deubiquitination R-HSA-5688426
Nervous system development R-HSA-9675108
Activation of NF-kappaB in B cells R-HSA-1169091
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of AXIN R-HSA-4641257
Regulation of PTEN stability and activity R-HSA-8948751
Cell Cycle, Mitotic R-HSA-69278
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Signaling by Interleukins R-HSA-449147
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Mitotic Anaphase R-HSA-68882
Stabilization of p53 R-HSA-69541
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PCP/CE pathway R-HSA-4086400
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
Infectious disease R-HSA-5663205
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Signaling by Hedgehog R-HSA-5358351
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Replication R-HSA-69306
Signaling by NOTCH4 R-HSA-9013694
Defective CFTR causes cystic fibrosis R-HSA-5678895
Asymmetric localization of PCP proteins R-HSA-4608870
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by the B Cell Receptor (BCR) R-HSA-983705
DNA Replication Pre-Initiation R-HSA-69002
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stress R-HSA-2262752
Separation of Sister Chromatids R-HSA-2467813
Cellular response to chemical stress R-HSA-9711123
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Transition R-HSA-69275
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
TCF dependent signaling in response to WNT R-HSA-201681
Degradation of DVL R-HSA-4641258
Hedgehog 'on' state R-HSA-5632684
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
TCR signaling R-HSA-202403
FCERI mediated NF-kB activation R-HSA-2871837
Negative regulation of NOTCH4 signaling R-HSA-9604323
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Nuclear events mediated by NFE2L2 R-HSA-9759194
Metabolism of proteins R-HSA-392499
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
p53-Dependent G1 DNA Damage Response R-HSA-69563
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Metabolism of amino acids and derivatives R-HSA-71291
Cellular response to hypoxia R-HSA-1234174
Nuclear events mediated by NFE2L2 R-HSA-9759194
Neddylation R-HSA-8951664
Hedgehog 'on' state R-HSA-5632684
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of RAS by GAPs R-HSA-5658442
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TCF dependent signaling in response to WNT R-HSA-201681
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Interleukins R-HSA-449147
Cyclin E associated events during G1/S transition R-HSA-69202
Infectious disease R-HSA-5663205
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation by RUNX2 R-HSA-8878166
Negative regulation of NOTCH4 signaling R-HSA-9604323
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Hh mutants are degraded by ERAD R-HSA-5362768
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
PCP/CE pathway R-HSA-4086400
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of Apoptosis R-HSA-169911
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Transcriptional regulation by RUNX3 R-HSA-8878159
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
Downstream TCR signaling R-HSA-202424
ABC transporter disorders R-HSA-5619084
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
ER-Phagosome pathway R-HSA-1236974
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S Transition R-HSA-69206
MAPK6/MAPK4 signaling R-HSA-5687128
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
G2/M Checkpoints R-HSA-69481
Regulation of RUNX2 expression and activity R-HSA-8939902
Cytokine Signaling in Immune system R-HSA-1280215
Orc1 removal from chromatin R-HSA-68949
S Phase R-HSA-69242
C-type lectin receptors (CLRs) R-HSA-5621481
M Phase R-HSA-68886
Beta-catenin independent WNT signaling R-HSA-3858494
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Antigen processing-Cross presentation R-HSA-1236975
p53-Independent DNA Damage Response R-HSA-69610
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Synthesis of DNA R-HSA-69239
DNA Replication Pre-Initiation R-HSA-69002
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Disorders of transmembrane transporters R-HSA-5619115
KEAP1-NFE2L2 pathway R-HSA-9755511
Deubiquitination R-HSA-5688426
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Axon guidance R-HSA-422475
Intracellular signaling by second messengers R-HSA-9006925
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Assembly of the pre-replicative complex R-HSA-68867
Metabolism of RNA R-HSA-8953854
Cellular responses to stimuli R-HSA-8953897
Degradation of DVL R-HSA-4641258
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Hh mutants abrogate ligand secretion R-HSA-5387390
Mitotic Anaphase R-HSA-68882
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1 DNA Damage Response R-HSA-69563
FCERI mediated NF-kB activation R-HSA-2871837
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hedgehog ligand biogenesis R-HSA-5358346
RAF/MAP kinase cascade R-HSA-5673001
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
Cellular response to chemical stress R-HSA-9711123
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Apoptosis R-HSA-109581
Immune System R-HSA-168256
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cell Cycle R-HSA-1640170
TCR signaling R-HSA-202403
Signaling by the B Cell Receptor (BCR) R-HSA-983705
HIV Infection R-HSA-162906
Regulation of RUNX3 expression and activity R-HSA-8941858
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Regulation of mitotic cell cycle R-HSA-453276
Signaling by NOTCH4 R-HSA-9013694
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
UCH proteinases R-HSA-5689603
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signal Transduction R-HSA-162582
Signaling by ROBO receptors R-HSA-376176
PIP3 activates AKT signaling R-HSA-1257604
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Host Interactions of HIV factors R-HSA-162909
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK1/MAPK3 signaling R-HSA-5684996
Metabolism of amino acids and derivatives R-HSA-71291
Programmed Cell Death R-HSA-5357801
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of RUNX2 expression and activity R-HSA-8939902
CLEC7A (Dectin-1) signaling R-HSA-5607764
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by ROBO receptors R-HSA-376176
ABC-family proteins mediated transport R-HSA-382556
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cyclin E associated events during G1/S transition R-HSA-69202
PIP3 activates AKT signaling R-HSA-1257604
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cytokine Signaling in Immune system R-HSA-1280215
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX2 R-HSA-8878166
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
Regulation of RAS by GAPs R-HSA-5658442
G2/M Transition R-HSA-69275
Hh mutants abrogate ligand secretion R-HSA-5387390
Metabolism R-HSA-1430728
Hedgehog ligand biogenesis R-HSA-5358346
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Infectious disease R-HSA-5663205
MAPK6/MAPK4 signaling R-HSA-5687128
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Interleukin-1 family signaling R-HSA-446652
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
Signaling by NOTCH R-HSA-157118
Negative regulation of NOTCH4 signaling R-HSA-9604323
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Metabolism of polyamines R-HSA-351202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Hedgehog 'off' state R-HSA-5610787
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Metabolism of amino acids and derivatives R-HSA-71291
G1/S Transition R-HSA-69206
TCR signaling R-HSA-202403
Cellular responses to stress R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
Disease R-HSA-1643685
G2/M Checkpoints R-HSA-69481
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G1 phase and G1/S transition R-HSA-453279
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Programmed Cell Death R-HSA-5357801
M Phase R-HSA-68886
Signaling by Interleukins R-HSA-449147
Generic Transcription Pathway R-HSA-212436
Cellular response to hypoxia R-HSA-1234174
Post-translational protein modification R-HSA-597592
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Nervous system development R-HSA-9675108
Transcriptional regulation by RUNX1 R-HSA-8878171
Neddylation R-HSA-8951664
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Gene expression (Transcription) R-HSA-74160
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
NIK-->noncanonical NF-kB signaling R-HSA-5676590
UCH proteinases R-HSA-5689603
Regulation of PTEN stability and activity R-HSA-8948751
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PCP/CE pathway R-HSA-4086400
Antigen processing-Cross presentation R-HSA-1236975
Asymmetric localization of PCP proteins R-HSA-4608870
Apoptosis R-HSA-109581
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Innate Immune System R-HSA-168249
MAPK1/MAPK3 signaling R-HSA-5684996
Cellular responses to stimuli R-HSA-8953897
Vpu mediated degradation of CD4 R-HSA-180534
Transcriptional regulation by RUNX3 R-HSA-8878159
Intracellular signaling by second messengers R-HSA-9006925
FCERI mediated NF-kB activation R-HSA-2871837
MAPK family signaling cascades R-HSA-5683057
Degradation of GLI2 by the proteasome R-HSA-5610783
Beta-catenin independent WNT signaling R-HSA-3858494
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
G1/S DNA Damage Checkpoints R-HSA-69615
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle R-HSA-1640170
Axon guidance R-HSA-422475
S Phase R-HSA-69242
Signaling by WNT R-HSA-195721
Mitotic Metaphase and Anaphase R-HSA-2555396
Metabolism of RNA R-HSA-8953854
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
DNA Replication Pre-Initiation R-HSA-69002
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Developmental Biology R-HSA-1266738
Regulation of mitotic cell cycle R-HSA-453276
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Stabilization of p53 R-HSA-69541
Switching of origins to a post-replicative state R-HSA-69052
Hh mutants are degraded by ERAD R-HSA-5362768
Degradation of AXIN R-HSA-4641257
Vif-mediated degradation of APOBEC3G R-HSA-180585
Defective CFTR causes cystic fibrosis R-HSA-5678895
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
C-type lectin receptors (CLRs) R-HSA-5621481
PTEN Regulation R-HSA-6807070
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH4 R-HSA-9013694
Signal Transduction R-HSA-162582
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH R-HSA-157118
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Activation of NF-kappaB in B cells R-HSA-1169091
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Disease R-HSA-1643685
Asymmetric localization of PCP proteins R-HSA-4608870
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Regulation of RAS by GAPs R-HSA-5658442
Regulation of RUNX2 expression and activity R-HSA-8939902
Stabilization of p53 R-HSA-69541
ABC transporter disorders R-HSA-5619084
Programmed Cell Death R-HSA-5357801
Nuclear events mediated by NFE2L2 R-HSA-9759194
p53-Independent DNA Damage Response R-HSA-69610
Innate Immune System R-HSA-168249
Signaling by ROBO receptors R-HSA-376176
Ub-specific processing proteases R-HSA-5689880
Beta-catenin independent WNT signaling R-HSA-3858494
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Synthesis of DNA R-HSA-69239
Signaling by Hedgehog R-HSA-5358351
KEAP1-NFE2L2 pathway R-HSA-9755511
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCR signaling R-HSA-202403
Defective CFTR causes cystic fibrosis R-HSA-5678895
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Interleukin-1 family signaling R-HSA-446652
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to chemical stress R-HSA-9711123
Degradation of AXIN R-HSA-4641257
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK family signaling cascades R-HSA-5683057
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cellular responses to stress R-HSA-2262752
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'on' state R-HSA-5632684
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Intracellular signaling by second messengers R-HSA-9006925
M Phase R-HSA-68886
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
S Phase R-HSA-69242
Adaptive Immune System R-HSA-1280218
G2/M Checkpoints R-HSA-69481
Negative regulation of NOTCH4 signaling R-HSA-9604323
RNA Polymerase II Transcription R-HSA-73857
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
HIV Infection R-HSA-162906
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
CLEC7A (Dectin-1) signaling R-HSA-5607764
ER-Phagosome pathway R-HSA-1236974
Transcriptional regulation by RUNX3 R-HSA-8878159
Downstream TCR signaling R-HSA-202424
Metabolism of polyamines R-HSA-351202
Regulation of PTEN stability and activity R-HSA-8948751
Infectious disease R-HSA-5663205
Interleukin-1 signaling R-HSA-9020702
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of mitotic cell cycle R-HSA-453276
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
PTEN Regulation R-HSA-6807070
Class I MHC mediated antigen processing & presentation R-HSA-983169
Generic Transcription Pathway R-HSA-212436
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Orc1 removal from chromatin R-HSA-68949
FCERI mediated NF-kB activation R-HSA-2871837
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
UCH proteinases R-HSA-5689603
Mitotic G1 phase and G1/S transition R-HSA-453279
Developmental Biology R-HSA-1266738
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Hedgehog 'off' state R-HSA-5610787
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Separation of Sister Chromatids R-HSA-2467813
Degradation of DVL R-HSA-4641258
Metabolism of RNA R-HSA-8953854
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Metabolism of amino acids and derivatives R-HSA-71291
PCP/CE pathway R-HSA-4086400
Transport of small molecules R-HSA-382551
Vpu mediated degradation of CD4 R-HSA-180534
TCF dependent signaling in response to WNT R-HSA-201681
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic G2-G2/M phases R-HSA-453274
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Metabolism R-HSA-1430728
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Signaling by NOTCH4 R-HSA-9013694
Axon guidance R-HSA-422475
C-type lectin receptors (CLRs) R-HSA-5621481
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Host Interactions of HIV factors R-HSA-162909
Disorders of transmembrane transporters R-HSA-5619115
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cell Cycle Checkpoints R-HSA-69620
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Anaphase R-HSA-68882
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
p53-Dependent G1 DNA Damage Response R-HSA-69563
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX1 R-HSA-8878171
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of beta-catenin by the destruction complex R-HSA-195253
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular response to hypoxia R-HSA-1234174
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Hh mutants abrogate ligand secretion R-HSA-5387390
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of Apoptosis R-HSA-169911
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
RNA Polymerase II Transcription R-HSA-73857
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 signaling R-HSA-9020702
ABC-family proteins mediated transport R-HSA-382556
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Cell Cycle R-HSA-1640170
UCH proteinases R-HSA-5689603
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cytokine Signaling in Immune system R-HSA-1280215
Mitotic G1 phase and G1/S transition R-HSA-453279
Hedgehog 'on' state R-HSA-5632684
Defective CFTR causes cystic fibrosis R-HSA-5678895
Hh mutants are degraded by ERAD R-HSA-5362768
Generic Transcription Pathway R-HSA-212436
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
Cyclin E associated events during G1/S transition R-HSA-69202
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Class I MHC mediated antigen processing & presentation R-HSA-983169
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by ROBO receptors R-HSA-376176
TCR signaling R-HSA-202403
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular response to hypoxia R-HSA-1234174
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Infectious disease R-HSA-5663205
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
DNA Replication R-HSA-69306
PIP3 activates AKT signaling R-HSA-1257604
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
PTEN Regulation R-HSA-6807070
Synthesis of DNA R-HSA-69239
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Post-translational protein modification R-HSA-597592
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to chemical stress R-HSA-9711123
C-type lectin receptors (CLRs) R-HSA-5621481
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
Neddylation R-HSA-8951664
Ub-specific processing proteases R-HSA-5689880
Metabolism R-HSA-1430728
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle, Mitotic R-HSA-69278
Signaling by NOTCH R-HSA-157118
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog ligand biogenesis R-HSA-5358346
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Disorders of transmembrane transporters R-HSA-5619115
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic Anaphase R-HSA-68882
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Transport of small molecules R-HSA-382551
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Mitotic Metaphase and Anaphase R-HSA-2555396
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
Regulation of mitotic cell cycle R-HSA-453276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Degradation of beta-catenin by the destruction complex R-HSA-195253
Separation of Sister Chromatids R-HSA-2467813
Regulation of RUNX3 expression and activity R-HSA-8941858
ER-Phagosome pathway R-HSA-1236974
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK1/MAPK3 signaling R-HSA-5684996
HIV Infection R-HSA-162906
Cellular responses to stimuli R-HSA-8953897
Hedgehog 'off' state R-HSA-5610787
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Downstream TCR signaling R-HSA-202424
Apoptosis R-HSA-109581
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
Metabolism of proteins R-HSA-392499
Assembly of the pre-replicative complex R-HSA-68867
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
G2/M Checkpoints R-HSA-69481
CLEC7A (Dectin-1) signaling R-HSA-5607764
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of RAS by GAPs R-HSA-5658442
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX2 R-HSA-8878166
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
TCF dependent signaling in response to WNT R-HSA-201681
Cell Cycle Checkpoints R-HSA-69620
MAPK family signaling cascades R-HSA-5683057
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants abrogate ligand secretion R-HSA-5387390
Immune System R-HSA-168256
Regulation of Apoptosis R-HSA-169911
PCP/CE pathway R-HSA-4086400
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Disease R-HSA-1643685
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
p53-Independent DNA Damage Response R-HSA-69610
Axon guidance R-HSA-422475
Mitotic G2-G2/M phases R-HSA-453274
RAF/MAP kinase cascade R-HSA-5673001
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stress R-HSA-2262752
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Host Interactions of HIV factors R-HSA-162909
Adaptive Immune System R-HSA-1280218
Deubiquitination R-HSA-5688426
Innate Immune System R-HSA-168249
Metabolism of polyamines R-HSA-351202
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
M Phase R-HSA-68886
Transcriptional regulation by RUNX3 R-HSA-8878159
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202

Expression Atlas ENSG00000159377
NCBI gene (formerly Entrezgene) 5692
GeneCards 9541
HGNC Symbol HGNC:9541
MIM gene 602177
MIM morbid 617591
UniProtKB Gene Name P28070
WikiGene 5692
Gene: CSNK1E
Ensembl ID : ENSG00000213923
Description: casein kinase 1 epsilon
Gene Synonyms: CKIE,CKIEPSILON,HCKIE
1 APIs:
265 Possible Orthologues:

G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Mitotic G2-G2/M phases R-HSA-453274
Circadian Clock R-HSA-400253
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
AURKA Activation by TPX2 R-HSA-8854518
Metabolism of RNA R-HSA-8953854
Cell Cycle R-HSA-1640170
Centrosome maturation R-HSA-380287
Organelle biogenesis and maintenance R-HSA-1852241
Signaling by WNT R-HSA-195721
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
Cilium Assembly R-HSA-5617833
Centrosome maturation R-HSA-380287
rRNA processing in the nucleus and cytosol R-HSA-8868773
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Organelle biogenesis and maintenance R-HSA-1852241
TCF dependent signaling in response to WNT R-HSA-201681
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle R-HSA-1640170
Mitotic Prometaphase R-HSA-68877
rRNA processing R-HSA-72312
G2/M Transition R-HSA-69275
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Signaling by WNT R-HSA-195721
Metabolism of RNA R-HSA-8953854
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
M Phase R-HSA-68886
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cell Cycle, Mitotic R-HSA-69278
Cilium Assembly R-HSA-5617833
WNT mediated activation of DVL R-HSA-201688
Cilium Assembly R-HSA-5617833
M Phase R-HSA-68886
rRNA processing in the nucleus and cytosol R-HSA-8868773
Circadian Clock R-HSA-400253
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Loss of Nlp from mitotic centrosomes R-HSA-380259
Organelle biogenesis and maintenance R-HSA-1852241
Centrosome maturation R-HSA-380287
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
G2/M Transition R-HSA-69275
WNT mediated activation of DVL R-HSA-201688
Mitotic Prometaphase R-HSA-68877
Signaling by WNT R-HSA-195721
rRNA processing R-HSA-72312
AURKA Activation by TPX2 R-HSA-8854518
Signal Transduction R-HSA-162582
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of RNA R-HSA-8953854
Cell Cycle R-HSA-1640170
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
Organelle biogenesis and maintenance R-HSA-1852241
G2/M Transition R-HSA-69275
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cell Cycle R-HSA-1640170
WNT mediated activation of DVL R-HSA-201688
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
rRNA processing R-HSA-72312
Centrosome maturation R-HSA-380287
Signal Transduction R-HSA-162582
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Metabolism of RNA R-HSA-8953854
M Phase R-HSA-68886
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Signaling by WNT R-HSA-195721
Circadian Clock R-HSA-400253
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Cilium Assembly R-HSA-5617833
AURKA Activation by TPX2 R-HSA-8854518
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
M Phase R-HSA-68886
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
rRNA processing R-HSA-72312
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Mitotic Prometaphase R-HSA-68877
WNT mediated activation of DVL R-HSA-201688
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Metabolism of RNA R-HSA-8953854
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Signaling by WNT R-HSA-195721
rRNA processing in the nucleus and cytosol R-HSA-8868773
Centrosome maturation R-HSA-380287
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of Nlp from mitotic centrosomes R-HSA-380259
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Circadian Clock R-HSA-400253
Organelle biogenesis and maintenance R-HSA-1852241
TCF dependent signaling in response to WNT R-HSA-201681
Cilium Assembly R-HSA-5617833
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
rRNA processing in the nucleus and cytosol R-HSA-8868773
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Anchoring of the basal body to the plasma membrane R-HSA-5620912
TCF dependent signaling in response to WNT R-HSA-201681
Signaling by WNT R-HSA-195721
Mitotic Prometaphase R-HSA-68877
Circadian Clock R-HSA-400253
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Cilium Assembly R-HSA-5617833
rRNA processing R-HSA-72312
Metabolism of RNA R-HSA-8953854
Mitotic G2-G2/M phases R-HSA-453274
AURKA Activation by TPX2 R-HSA-8854518
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
G2/M Transition R-HSA-69275
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Cell Cycle R-HSA-1640170
Centrosome maturation R-HSA-380287
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
TCF dependent signaling in response to WNT R-HSA-201681
Signal Transduction R-HSA-162582
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
G2/M Transition R-HSA-69275
rRNA processing in the nucleus and cytosol R-HSA-8868773
Mitotic Prometaphase R-HSA-68877
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
WNT mediated activation of DVL R-HSA-201688
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Loss of Nlp from mitotic centrosomes R-HSA-380259
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
rRNA processing R-HSA-72312
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
Centrosome maturation R-HSA-380287
Cilium Assembly R-HSA-5617833
Circadian Clock R-HSA-400253
AURKA Activation by TPX2 R-HSA-8854518
M Phase R-HSA-68886
Metabolism of RNA R-HSA-8953854
Organelle biogenesis and maintenance R-HSA-1852241
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Cell Cycle R-HSA-1640170
Signaling by WNT R-HSA-195721
Cilium Assembly R-HSA-5617833
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
AURKA Activation by TPX2 R-HSA-8854518
WNT mediated activation of DVL R-HSA-201688
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
rRNA processing R-HSA-72312
Mitotic G2-G2/M phases R-HSA-453274
Metabolism of RNA R-HSA-8953854
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Mitotic Prometaphase R-HSA-68877
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
TCF dependent signaling in response to WNT R-HSA-201681
Organelle biogenesis and maintenance R-HSA-1852241
Loss of Nlp from mitotic centrosomes R-HSA-380259
rRNA processing in the nucleus and cytosol R-HSA-8868773
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
rRNA processing R-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
Metabolism of RNA R-HSA-8953854
WNT mediated activation of DVL R-HSA-201688
AURKA Activation by TPX2 R-HSA-8854518
Mitotic Prometaphase R-HSA-68877
M Phase R-HSA-68886
Cell Cycle, Mitotic R-HSA-69278
Loss of Nlp from mitotic centrosomes R-HSA-380259
Mitotic G2-G2/M phases R-HSA-453274
G2/M Transition R-HSA-69275
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Circadian Clock R-HSA-400253
Signaling by WNT R-HSA-195721
Anchoring of the basal body to the plasma membrane R-HSA-5620912
rRNA processing in the nucleus and cytosol R-HSA-8868773
TCF dependent signaling in response to WNT R-HSA-201681
Cilium Assembly R-HSA-5617833
Signal Transduction R-HSA-162582
Organelle biogenesis and maintenance R-HSA-1852241
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Centrosome maturation R-HSA-380287
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Cell Cycle R-HSA-1640170
Organelle biogenesis and maintenance R-HSA-1852241
Circadian Clock R-HSA-400253
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
Centrosome maturation R-HSA-380287
G2/M Transition R-HSA-69275
Signaling by WNT R-HSA-195721
M Phase R-HSA-68886
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
TCF dependent signaling in response to WNT R-HSA-201681
WNT mediated activation of DVL R-HSA-201688
Metabolism of RNA R-HSA-8953854
Loss of Nlp from mitotic centrosomes R-HSA-380259
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
AURKA Activation by TPX2 R-HSA-8854518
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Mitotic G2-G2/M phases R-HSA-453274
Cell Cycle, Mitotic R-HSA-69278
Mitotic Prometaphase R-HSA-68877
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Cilium Assembly R-HSA-5617833
Cell Cycle R-HSA-1640170
rRNA processing in the nucleus and cytosol R-HSA-8868773
rRNA processing in the nucleus and cytosol R-HSA-8868773
Metabolism of RNA R-HSA-8953854
Cilium Assembly R-HSA-5617833
AURKA Activation by TPX2 R-HSA-8854518
Recruitment of NuMA to mitotic centrosomes R-HSA-380320
Loss of Nlp from mitotic centrosomes R-HSA-380259
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226
M Phase R-HSA-68886
WNT mediated activation of DVL R-HSA-201688
Mitotic Prometaphase R-HSA-68877
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
Mitotic G2-G2/M phases R-HSA-453274
Signaling by WNT R-HSA-195721
Centrosome maturation R-HSA-380287
Signal Transduction R-HSA-162582
rRNA processing R-HSA-72312
TCF dependent signaling in response to WNT R-HSA-201681
Anchoring of the basal body to the plasma membrane R-HSA-5620912
Organelle biogenesis and maintenance R-HSA-1852241
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942
Circadian Clock R-HSA-400253
Cell Cycle R-HSA-1640170

Expression Atlas ENSG00000213923
NCBI gene (formerly Entrezgene) 1454
GeneCards 2453
HGNC Symbol HGNC:2453
MIM gene 600863
UniProtKB Gene Name Q5U045
WikiGene 1454
Gene: ENPP2
Ensembl ID : ENSG00000136960
Description: ectonucleotide pyrophosphatase/phosphodiesterase 2
Gene Synonyms: ATX,PD-IALPHA,PDNP2
1 APIs:
227 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Vitamin B5 (pantothenate) metabolism R-HSA-199220

Expression Atlas ENSG00000136960
NCBI gene (formerly Entrezgene) 5168
GeneCards 3357
HGNC Symbol HGNC:3357
MIM gene 601060
UniProtKB Gene Name Q13822
WikiGene 5168
Gene: CTSK
Ensembl ID : ENSG00000143387
Description: cathepsin K
Gene Synonyms: CTSO,CTSO2,PKND,PYCD
2 APIs:
246 Possible Orthologues:

Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
MHC class II antigen presentation R-HSA-2132295
Trafficking and processing of endosomal TLR R-HSA-1679131
Generic Transcription Pathway R-HSA-212436
Toll-like Receptor Cascades R-HSA-168898
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation by RUNX1 R-HSA-8878171
Degradation of the extracellular matrix R-HSA-1474228
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Collagen degradation R-HSA-1442490
Gene expression (Transcription) R-HSA-74160
Degradation of the extracellular matrix R-HSA-1474228
Toll-like Receptor Cascades R-HSA-168898
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Trafficking and processing of endosomal TLR R-HSA-1679131
Activation of Matrix Metalloproteinases R-HSA-1592389
Generic Transcription Pathway R-HSA-212436
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
RNA Polymerase II Transcription R-HSA-73857
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX1 R-HSA-8878171
MHC class II antigen presentation R-HSA-2132295
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
Trafficking and processing of endosomal TLR R-HSA-1679131
Innate Immune System R-HSA-168249
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Extracellular matrix organization R-HSA-1474244
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Activation of Matrix Metalloproteinases R-HSA-1592389
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Collagen degradation R-HSA-1442490
Adaptive Immune System R-HSA-1280218
Toll-like Receptor Cascades R-HSA-168898
Gene expression (Transcription) R-HSA-74160
Activation of Matrix Metalloproteinases R-HSA-1592389
Immune System R-HSA-168256
Degradation of the extracellular matrix R-HSA-1474228
MHC class II antigen presentation R-HSA-2132295
Trafficking and processing of endosomal TLR R-HSA-1679131
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX1 R-HSA-8878171
Extracellular matrix organization R-HSA-1474244
Generic Transcription Pathway R-HSA-212436
Innate Immune System R-HSA-168249
Collagen degradation R-HSA-1442490
Degradation of the extracellular matrix R-HSA-1474228
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Activation of Matrix Metalloproteinases R-HSA-1592389
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Trafficking and processing of endosomal TLR R-HSA-1679131
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Collagen degradation R-HSA-1442490
Trafficking and processing of endosomal TLR R-HSA-1679131
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
Activation of Matrix Metalloproteinases R-HSA-1592389
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Transcriptional regulation by RUNX1 R-HSA-8878171
Adaptive Immune System R-HSA-1280218
Extracellular matrix organization R-HSA-1474244
RNA Polymerase II Transcription R-HSA-73857
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Degradation of the extracellular matrix R-HSA-1474228
Innate Immune System R-HSA-168249
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Degradation of the extracellular matrix R-HSA-1474228
RNA Polymerase II Transcription R-HSA-73857
MHC class II antigen presentation R-HSA-2132295
Adaptive Immune System R-HSA-1280218
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Gene expression (Transcription) R-HSA-74160
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of Matrix Metalloproteinases R-HSA-1592389
Collagen degradation R-HSA-1442490
MHC class II antigen presentation R-HSA-2132295
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
Generic Transcription Pathway R-HSA-212436
Degradation of the extracellular matrix R-HSA-1474228
Activation of Matrix Metalloproteinases R-HSA-1592389
RNA Polymerase II Transcription R-HSA-73857
Extracellular matrix organization R-HSA-1474244
Toll-like Receptor Cascades R-HSA-168898
Trafficking and processing of endosomal TLR R-HSA-1679131
Collagen degradation R-HSA-1442490
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Transcriptional regulation by RUNX1 R-HSA-8878171
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Degradation of the extracellular matrix R-HSA-1474228
RNA Polymerase II Transcription R-HSA-73857
Toll-like Receptor Cascades R-HSA-168898
MHC class II antigen presentation R-HSA-2132295
Collagen degradation R-HSA-1442490
Transcriptional regulation by RUNX1 R-HSA-8878171
Activation of Matrix Metalloproteinases R-HSA-1592389
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242
Immune System R-HSA-168256
Extracellular matrix organization R-HSA-1474244
Trafficking and processing of endosomal TLR R-HSA-1679131
Adaptive Immune System R-HSA-1280218

Expression Atlas ENSG00000143387
NCBI gene (formerly Entrezgene) 1513
GeneCards 2536
HGNC Symbol HGNC:2536
MIM gene 601105
MIM morbid 265800
UniProtKB Gene Name Q5QP40
WikiGene 1513
Gene: MAPK11
Ensembl ID : ENSG00000185386
Description: mitogen-activated protein kinase 11
Gene Synonyms: P38-2,P38BETA,PRKM11,SAPK2
3 APIs:
201 Possible Orthologues:

Signaling by VEGF R-HSA-194138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Axon guidance R-HSA-422475
VEGFA-VEGFR2 Pathway R-HSA-4420097
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Generic Transcription Pathway R-HSA-212436
Signalling to ERKs R-HSA-187687
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPase Effectors R-HSA-195258
Netrin-1 signaling R-HSA-373752
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Metabolism of RNA R-HSA-8953854
Myogenesis R-HSA-525793
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
p38MAPK events R-HSA-171007
Mitochondrial biogenesis R-HSA-1592230
DSCAM interactions R-HSA-376172
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cellular responses to stress R-HSA-2262752
ERK/MAPK targets R-HSA-198753
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NOD1/2 Signaling Pathway R-HSA-168638
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll-like Receptor Cascades R-HSA-168898
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signalling to RAS R-HSA-167044
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Activation of the AP-1 family of transcription factors R-HSA-450341
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Organelle biogenesis and maintenance R-HSA-1852241
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Nervous system development R-HSA-9675108
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Signaling by NTRK1 (TRKA) R-HSA-187037
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Developmental Biology R-HSA-1266738
Interleukin-17 signaling R-HSA-448424
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Cellular Senescence R-HSA-2559583
p38MAPK events R-HSA-171007
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
ERK/MAPK targets R-HSA-198753
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Mitochondrial biogenesis R-HSA-1592230
DSCAM interactions R-HSA-376172
Regulation of TP53 Activity R-HSA-5633007
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll-like Receptor Cascades R-HSA-168898
Signal Transduction R-HSA-162582
Activation of the AP-1 family of transcription factors R-HSA-450341
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
NOD1/2 Signaling Pathway R-HSA-168638
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRKs R-HSA-166520
Organelle biogenesis and maintenance R-HSA-1852241
VEGFA-VEGFR2 Pathway R-HSA-4420097
Netrin-1 signaling R-HSA-373752
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional Regulation by TP53 R-HSA-3700989
MyD88-independent TLR4 cascade R-HSA-166166
Signalling to ERKs R-HSA-187687
Signalling to RAS R-HSA-167044
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Generic Transcription Pathway R-HSA-212436
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Axon guidance R-HSA-422475
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Myogenesis R-HSA-525793
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
Signaling by Interleukins R-HSA-449147
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Metabolism of RNA R-HSA-8953854
RHO GTPase Effectors R-HSA-195258
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by VEGF R-HSA-194138
Innate Immune System R-HSA-168249
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cellular responses to stress R-HSA-2262752
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Axon guidance R-HSA-422475
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAP kinase activation R-HSA-450294
Signalling to RAS R-HSA-167044
Signalling to ERKs R-HSA-187687
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of RNA R-HSA-8953854
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Rho GTPases R-HSA-194315
Toll-like Receptor Cascades R-HSA-168898
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by NTRKs R-HSA-166520
DSCAM interactions R-HSA-376172
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RHO GTPase Effectors R-HSA-195258
VEGFA-VEGFR2 Pathway R-HSA-4420097
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NOD1/2 Signaling Pathway R-HSA-168638
Transcriptional Regulation by TP53 R-HSA-3700989
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Gene expression (Transcription) R-HSA-74160
Netrin-1 signaling R-HSA-373752
Myogenesis R-HSA-525793
ERK/MAPK targets R-HSA-198753
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by VEGF R-HSA-194138
Mitochondrial biogenesis R-HSA-1592230
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
p38MAPK events R-HSA-171007
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by NTRK1 (TRKA) R-HSA-187037
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Interleukin-17 signaling R-HSA-448424
RNA Polymerase II Transcription R-HSA-73857
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88 cascade initiated on plasma membrane R-HSA-975871
Organelle biogenesis and maintenance R-HSA-1852241
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Myogenesis R-HSA-525793
Interleukin-17 signaling R-HSA-448424
MAP kinase activation R-HSA-450294
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stimuli R-HSA-8953897
Signaling by NTRKs R-HSA-166520
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular Senescence R-HSA-2559583
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to ERKs R-HSA-187687
NOD1/2 Signaling Pathway R-HSA-168638
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by VEGF R-HSA-194138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RHO GTPase Effectors R-HSA-195258
p38MAPK events R-HSA-171007
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
DSCAM interactions R-HSA-376172
Metabolism of RNA R-HSA-8953854
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signalling to RAS R-HSA-167044
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Organelle biogenesis and maintenance R-HSA-1852241
Mitochondrial biogenesis R-HSA-1592230
Innate Immune System R-HSA-168249
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Rho GTPases R-HSA-194315
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Netrin-1 signaling R-HSA-373752
Developmental Biology R-HSA-1266738
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
VEGFA-VEGFR2 Pathway R-HSA-4420097
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
Organelle biogenesis and maintenance R-HSA-1852241
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Myogenesis R-HSA-525793
RNA Polymerase II Transcription R-HSA-73857
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DSCAM interactions R-HSA-376172
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Developmental Biology R-HSA-1266738
Netrin-1 signaling R-HSA-373752
RHO GTPase Effectors R-HSA-195258
Transcriptional Regulation by TP53 R-HSA-3700989
p38MAPK events R-HSA-171007
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by VEGF R-HSA-194138
Metabolism of RNA R-HSA-8953854
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Gene expression (Transcription) R-HSA-74160
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NOD1/2 Signaling Pathway R-HSA-168638
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signalling to RAS R-HSA-167044
Signaling by Interleukins R-HSA-449147
Signaling by Rho GTPases R-HSA-194315
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitochondrial biogenesis R-HSA-1592230
Cellular responses to stimuli R-HSA-8953897
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signal Transduction R-HSA-162582
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Interleukin-17 signaling R-HSA-448424
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Toll-like Receptor Cascades R-HSA-168898
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Rho GTPases R-HSA-194315
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Generic Transcription Pathway R-HSA-212436
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by NTRKs R-HSA-166520
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Interleukins R-HSA-449147
Organelle biogenesis and maintenance R-HSA-1852241
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERK/MAPK targets R-HSA-198753
Signaling by VEGF R-HSA-194138
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular Senescence R-HSA-2559583
NOD1/2 Signaling Pathway R-HSA-168638
Myogenesis R-HSA-525793
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signalling to RAS R-HSA-167044
Signalling to ERKs R-HSA-187687
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Developmental Biology R-HSA-1266738
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity R-HSA-5633007
p38MAPK events R-HSA-171007
Signaling by NTRK1 (TRKA) R-HSA-187037
Netrin-1 signaling R-HSA-373752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DSCAM interactions R-HSA-376172
MAP kinase activation R-HSA-450294
Mitochondrial biogenesis R-HSA-1592230
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
RHO GTPase Effectors R-HSA-195258
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll-like Receptor Cascades R-HSA-168898
MyD88-independent TLR4 cascade R-HSA-166166
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Interleukins R-HSA-449147
ERK/MAPK targets R-HSA-198753
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
DSCAM interactions R-HSA-376172
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by VEGF R-HSA-194138
Nervous system development R-HSA-9675108
Signalling to ERKs R-HSA-187687
Interleukin-17 signaling R-HSA-448424
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
VEGFA-VEGFR2 Pathway R-HSA-4420097
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity R-HSA-5633007
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
Metabolism of RNA R-HSA-8953854
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signalling to RAS R-HSA-167044
Organelle biogenesis and maintenance R-HSA-1852241
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
p38MAPK events R-HSA-171007
Oxidative Stress Induced Senescence R-HSA-2559580
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Developmental Biology R-HSA-1266738
Netrin-1 signaling R-HSA-373752
Mitochondrial biogenesis R-HSA-1592230
Myogenesis R-HSA-525793
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Axon guidance R-HSA-422475
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPase Effectors R-HSA-195258
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of TP53 Activity R-HSA-5633007
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
NOD1/2 Signaling Pathway R-HSA-168638
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Netrin-1 signaling R-HSA-373752
Transcriptional Regulation by TP53 R-HSA-3700989
MAP kinase activation R-HSA-450294
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Cytokine Signaling in Immune system R-HSA-1280215
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
p38MAPK events R-HSA-171007
Axon guidance R-HSA-422475
DSCAM interactions R-HSA-376172
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Mitochondrial biogenesis R-HSA-1592230
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signalling to ERKs R-HSA-187687
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
ERK/MAPK targets R-HSA-198753
Myogenesis R-HSA-525793
RNA Polymerase II Transcription R-HSA-73857
MyD88-independent TLR4 cascade R-HSA-166166
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Organelle biogenesis and maintenance R-HSA-1852241
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
p38MAPK events R-HSA-171007
Metabolism of RNA R-HSA-8953854
Organelle biogenesis and maintenance R-HSA-1852241
activated TAK1 mediates p38 MAPK activation R-HSA-450302
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NOD1/2 Signaling Pathway R-HSA-168638
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signalling to RAS R-HSA-167044
Cellular responses to stress R-HSA-2262752
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by NTRK1 (TRKA) R-HSA-187037
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signalling to ERKs R-HSA-187687
Developmental Biology R-HSA-1266738
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll-like Receptor Cascades R-HSA-168898
Cellular Senescence R-HSA-2559583
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
DSCAM interactions R-HSA-376172
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Axon guidance R-HSA-422475
Signaling by VEGF R-HSA-194138
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Nervous system development R-HSA-9675108
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAP kinase activation R-HSA-450294
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
RHO GTPase Effectors R-HSA-195258
RNA Polymerase II Transcription R-HSA-73857
Myogenesis R-HSA-525793
Mitochondrial biogenesis R-HSA-1592230
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
Signaling by NTRKs R-HSA-166520
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ERK/MAPK targets R-HSA-198753
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
MyD88 cascade initiated on plasma membrane R-HSA-975871
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Regulation of TP53 Activity R-HSA-5633007
Innate Immune System R-HSA-168249
Mitochondrial biogenesis R-HSA-1592230
Axon guidance R-HSA-422475
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular Senescence R-HSA-2559583
Interleukin-17 signaling R-HSA-448424
ERK/MAPK targets R-HSA-198753
Signaling by NTRKs R-HSA-166520
Immune System R-HSA-168256
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Transcriptional Regulation by TP53 R-HSA-3700989
Organelle biogenesis and maintenance R-HSA-1852241
Signalling to RAS R-HSA-167044
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DSCAM interactions R-HSA-376172
Signaling by VEGF R-HSA-194138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll-like Receptor Cascades R-HSA-168898
Netrin-1 signaling R-HSA-373752
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Activation of the AP-1 family of transcription factors R-HSA-450341
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of RNA R-HSA-8953854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of TP53 Activity R-HSA-5633007
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
MAP kinase activation R-HSA-450294
Signalling to ERKs R-HSA-187687
Myogenesis R-HSA-525793
VEGFA-VEGFR2 Pathway R-HSA-4420097
Oxidative Stress Induced Senescence R-HSA-2559580
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
p38MAPK events R-HSA-171007
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular responses to stress R-HSA-2262752
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
activated TAK1 mediates p38 MAPK activation R-HSA-450302
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164

Expression Atlas ENSG00000185386
NCBI gene (formerly Entrezgene) 5600
GeneCards 6873
HGNC Symbol HGNC:6873
MIM gene 602898
UniProtKB Gene Name Q15759
WikiGene 5600
Gene: CYP46A1
Ensembl ID : ENSG00000036530
Description: cytochrome P450 family 46 subfamily A member 1
Gene Synonyms: CYP46
1 APIs:
260 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Bile acid and bile salt metabolism R-HSA-194068
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Metabolism of steroids R-HSA-8957322
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Metabolism R-HSA-1430728
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Endogenous sterols R-HSA-211976
Bile acid and bile salt metabolism R-HSA-194068
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism R-HSA-1430728
Endogenous sterols R-HSA-211976
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Metabolism of lipids R-HSA-556833
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Endogenous sterols R-HSA-211976
Bile acid and bile salt metabolism R-HSA-194068
Biological oxidations R-HSA-211859
Synthesis of bile acids and bile salts R-HSA-192105
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of bile acids and bile salts R-HSA-192105
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Bile acid and bile salt metabolism R-HSA-194068
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of steroids R-HSA-8957322
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Synthesis of bile acids and bile salts R-HSA-192105
Bile acid and bile salt metabolism R-HSA-194068
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Metabolism of lipids R-HSA-556833
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Biological oxidations R-HSA-211859
Bile acid and bile salt metabolism R-HSA-194068
Synthesis of bile acids and bile salts R-HSA-192105
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism R-HSA-1430728
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775
Phase I - Functionalization of compounds R-HSA-211945
Cytochrome P450 - arranged by substrate type R-HSA-211897
Bile acid and bile salt metabolism R-HSA-194068
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859

Expression Atlas ENSG00000036530
NCBI gene (formerly Entrezgene) 10858
GeneCards 2641
HGNC Symbol HGNC:2641
MIM gene 604087
UniProtKB Gene Name Q9Y6A2
WikiGene 10858
Gene: CYP11B1
Ensembl ID : ENSG00000160882
Description: cytochrome P450 family 11 subfamily B member 1
Gene Synonyms: CPN1,CYP11B,FHI,P450C11
2 APIs:
40 Possible Orthologues:

Glucocorticoid biosynthesis R-HSA-194002
Defective CYP11B1 causes AH4 R-HSA-5579017
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Diseases of metabolism R-HSA-5668914
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Metabolism R-HSA-1430728
Diseases of metabolism R-HSA-5668914
Glucocorticoid biosynthesis R-HSA-194002
Biological oxidations R-HSA-211859
Endogenous sterols R-HSA-211976
Disease R-HSA-1643685
Metabolism of lipids R-HSA-556833
Cytochrome P450 - arranged by substrate type R-HSA-211897
Defective CYP11B1 causes AH4 R-HSA-5579017
Defective CYP11B1 causes AH4 R-HSA-5579017
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Diseases of metabolism R-HSA-5668914
Glucocorticoid biosynthesis R-HSA-194002
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833

Expression Atlas ENSG00000160882
NCBI gene (formerly Entrezgene) 1584
GeneCards 2591
HGNC Symbol HGNC:2591
MIM gene 610613
MIM morbid 202010
UniProtKB Gene Name Q4VAR0
WikiGene 1584
Gene: CA13
Ensembl ID : ENSG00000185015
Description: carbonic anhydrase 13
Gene Synonyms: CAXIII,FLJ37995,MGC59868
2 APIs:
291 Possible Orthologues:

Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029

Expression Atlas ENSG00000185015
NCBI gene (formerly Entrezgene) 377677
GeneCards 14914
HGNC Symbol HGNC:14914
MIM gene 611436
UniProtKB Gene Name Q8N1Q1
WikiGene 377677