Gene: CA4
Ensembl ID : ENSG00000167434
Description: carbonic anhydrase 4
Gene Synonyms: CAIV,CAR4,RP17
7 APIs:
334 Possible Orthologues:

Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
O2/CO2 exchange in erythrocytes R-HSA-1480926
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
O2/CO2 exchange in erythrocytes R-HSA-1480926
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Transport of small molecules R-HSA-382551
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
O2/CO2 exchange in erythrocytes R-HSA-1480926
Reversible hydration of carbon dioxide R-HSA-1475029
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Transport of small molecules R-HSA-382551
O2/CO2 exchange in erythrocytes R-HSA-1480926
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
O2/CO2 exchange in erythrocytes R-HSA-1480926
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Transport of small molecules R-HSA-382551
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Reversible hydration of carbon dioxide R-HSA-1475029
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Transport of small molecules R-HSA-382551
O2/CO2 exchange in erythrocytes R-HSA-1480926
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
O2/CO2 exchange in erythrocytes R-HSA-1480926
Reversible hydration of carbon dioxide R-HSA-1475029
Transport of small molecules R-HSA-382551
Reversible hydration of carbon dioxide R-HSA-1475029
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
O2/CO2 exchange in erythrocytes R-HSA-1480926
Metabolism R-HSA-1430728
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Transport of small molecules R-HSA-382551
O2/CO2 exchange in erythrocytes R-HSA-1480926
Metabolism R-HSA-1430728
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Reversible hydration of carbon dioxide R-HSA-1475029
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673
Metabolism R-HSA-1430728
O2/CO2 exchange in erythrocytes R-HSA-1480926
Transport of small molecules R-HSA-382551
Reversible hydration of carbon dioxide R-HSA-1475029

Expression Atlas ENSG00000167434
NCBI gene (formerly Entrezgene) 762
GeneCards 1375
HGNC Symbol HGNC:1375
MIM gene 114760
UniProtKB Gene Name P22748
WikiGene 762
Gene: PRKCI
Ensembl ID : ENSG00000163558
Description: protein kinase C iota
Gene Synonyms: DXS1179E,PKCI
5 APIs:
224 Possible Orthologues:

Pre-NOTCH Expression and Processing R-HSA-1912422
Tight junction interactions R-HSA-420029
p75NTR recruits signalling complexes R-HSA-209543
Cell junction organization R-HSA-446728
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Cell-Cell communication R-HSA-1500931
Death Receptor Signaling R-HSA-73887
Pre-NOTCH Transcription and Translation R-HSA-1912408
p75NTR signals via NF-kB R-HSA-193639
Cell-cell junction organization R-HSA-421270
p75NTR signals via NF-kB R-HSA-193639
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
p75NTR recruits signalling complexes R-HSA-209543
Tight junction interactions R-HSA-420029
Cell-cell junction organization R-HSA-421270
Signal Transduction R-HSA-162582
Death Receptor Signaling R-HSA-73887
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cell junction organization R-HSA-446728
Pre-NOTCH Expression and Processing R-HSA-1912422
Cell-Cell communication R-HSA-1500931
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signaling by NOTCH R-HSA-157118
Tight junction interactions R-HSA-420029
Cell-Cell communication R-HSA-1500931
Death Receptor Signaling R-HSA-73887
p75NTR signals via NF-kB R-HSA-193639
Signal Transduction R-HSA-162582
Cell-cell junction organization R-HSA-421270
Cell junction organization R-HSA-446728
Pre-NOTCH Expression and Processing R-HSA-1912422
p75 NTR receptor-mediated signalling R-HSA-193704
p75NTR recruits signalling complexes R-HSA-209543
Tight junction interactions R-HSA-420029
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cell junction organization R-HSA-446728
p75NTR signals via NF-kB R-HSA-193639
Signal Transduction R-HSA-162582
Cell-Cell communication R-HSA-1500931
p75NTR recruits signalling complexes R-HSA-209543
Death Receptor Signaling R-HSA-73887
Cell-cell junction organization R-HSA-421270
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Pre-NOTCH Expression and Processing R-HSA-1912422
Tight junction interactions R-HSA-420029
Cell-Cell communication R-HSA-1500931
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
Pre-NOTCH Expression and Processing R-HSA-1912422
p75NTR recruits signalling complexes R-HSA-209543
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signaling by NOTCH R-HSA-157118
p75NTR signals via NF-kB R-HSA-193639
Cell-cell junction organization R-HSA-421270
Cell junction organization R-HSA-446728
Signal Transduction R-HSA-162582
Pre-NOTCH Transcription and Translation R-HSA-1912408
Death Receptor Signaling R-HSA-73887
p75NTR signals via NF-kB R-HSA-193639
Cell-cell junction organization R-HSA-421270
Pre-NOTCH Expression and Processing R-HSA-1912422
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH R-HSA-157118
Tight junction interactions R-HSA-420029
Cell junction organization R-HSA-446728
Cell-Cell communication R-HSA-1500931
p75NTR recruits signalling complexes R-HSA-209543
Signal Transduction R-HSA-162582
Signal Transduction R-HSA-162582
p75NTR recruits signalling complexes R-HSA-209543
Cell junction organization R-HSA-446728
Cell-cell junction organization R-HSA-421270
Tight junction interactions R-HSA-420029
Death Receptor Signaling R-HSA-73887
p75NTR signals via NF-kB R-HSA-193639
Pre-NOTCH Expression and Processing R-HSA-1912422
Cell-Cell communication R-HSA-1500931
Signaling by NOTCH R-HSA-157118
p75 NTR receptor-mediated signalling R-HSA-193704
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signaling by NOTCH R-HSA-157118
Tight junction interactions R-HSA-420029
Death Receptor Signaling R-HSA-73887
Cell junction organization R-HSA-446728
p75NTR recruits signalling complexes R-HSA-209543
p75NTR signals via NF-kB R-HSA-193639
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signal Transduction R-HSA-162582
Cell-Cell communication R-HSA-1500931
Pre-NOTCH Expression and Processing R-HSA-1912422
Cell-cell junction organization R-HSA-421270
p75 NTR receptor-mediated signalling R-HSA-193704
p75NTR recruits signalling complexes R-HSA-209543
Pre-NOTCH Expression and Processing R-HSA-1912422
Cell-cell junction organization R-HSA-421270
p75 NTR receptor-mediated signalling R-HSA-193704
Signal Transduction R-HSA-162582
Pre-NOTCH Transcription and Translation R-HSA-1912408
Signaling by NOTCH R-HSA-157118
Death Receptor Signaling R-HSA-73887
Tight junction interactions R-HSA-420029
Cell junction organization R-HSA-446728
Cell-Cell communication R-HSA-1500931
p75NTR signals via NF-kB R-HSA-193639
Death Receptor Signaling R-HSA-73887
Cell-Cell communication R-HSA-1500931
Signaling by NOTCH R-HSA-157118
p75NTR signals via NF-kB R-HSA-193639
Tight junction interactions R-HSA-420029
Cell junction organization R-HSA-446728
p75NTR recruits signalling complexes R-HSA-209543
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Cell-cell junction organization R-HSA-421270
Pre-NOTCH Expression and Processing R-HSA-1912422
Pre-NOTCH Transcription and Translation R-HSA-1912408

Expression Atlas ENSG00000163558
NCBI gene (formerly Entrezgene) 5584
GeneCards 9404
HGNC Symbol HGNC:9404
MIM gene 600539
UniProtKB Gene Name P41743
WikiGene 5584
Gene: ROCK2
Ensembl ID : ENSG00000134318
Description: Rho associated coiled-coil containing protein kinase 2
Gene Synonyms:
11 APIs:
298 Possible Orthologues:

Axon guidance R-HSA-422475
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
RHOH GTPase cycle R-HSA-9013407
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase cycle R-HSA-9012999
RHOBTB1 GTPase cycle R-HSA-9013422
EPHB-mediated forward signaling R-HSA-3928662
Sema4D in semaphorin signaling R-HSA-400685
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
EPHA-mediated growth cone collapse R-HSA-3928663
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Semaphorin interactions R-HSA-373755
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate ROCKs R-HSA-5627117
GPCR downstream signalling R-HSA-388396
RHOH GTPase cycle R-HSA-9013407
Disease R-HSA-1643685
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHB-mediated forward signaling R-HSA-3928662
EPHA-mediated growth cone collapse R-HSA-3928663
SARS-CoV Infections R-HSA-9679506
Nervous system development R-HSA-9675108
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Signal Transduction R-HSA-162582
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Potential therapeutics for SARS R-HSA-9679191
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
RHO GTPase cycle R-HSA-9012999
RHOB GTPase cycle R-HSA-9013026
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
Developmental Biology R-HSA-1266738
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
RHO GTPase cycle R-HSA-9012999
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Potential therapeutics for SARS R-HSA-9679191
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by VEGF R-HSA-194138
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPase Effectors R-HSA-195258
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
Sema4D in semaphorin signaling R-HSA-400685
RHO GTPase Effectors R-HSA-195258
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
RHOBTB1 GTPase cycle R-HSA-9013422
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (12/13) signalling events R-HSA-416482
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
RHO GTPase cycle R-HSA-9012999
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Axon guidance R-HSA-422475
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
RHOH GTPase cycle R-HSA-9013407
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
RHOB GTPase cycle R-HSA-9013026
Developmental Biology R-HSA-1266738
Potential therapeutics for SARS R-HSA-9679191
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Semaphorin interactions R-HSA-373755
RHOBTB1 GTPase cycle R-HSA-9013422
GPCR downstream signalling R-HSA-388396
RHOA GTPase cycle R-HSA-8980692
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPases Activate ROCKs R-HSA-5627117
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHA-mediated growth cone collapse R-HSA-3928663
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Semaphorin interactions R-HSA-373755
Developmental Biology R-HSA-1266738
Signaling by VEGF R-HSA-194138
RHO GTPase cycle R-HSA-9012999
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
G alpha (12/13) signalling events R-HSA-416482
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Sema4D in semaphorin signaling R-HSA-400685
SARS-CoV Infections R-HSA-9679506
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
RHO GTPases Activate ROCKs R-HSA-5627117
RHOBTB GTPase Cycle R-HSA-9706574
GPCR downstream signalling R-HSA-388396
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHO GTPase Effectors R-HSA-195258
RHOH GTPase cycle R-HSA-9013407
Signaling by GPCR R-HSA-372790
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
RHOH GTPase cycle R-HSA-9013407
RHOBTB GTPase Cycle R-HSA-9706574
RHOA GTPase cycle R-HSA-8980692
RHOC GTPase cycle R-HSA-9013106
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
Developmental Biology R-HSA-1266738
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOB GTPase cycle R-HSA-9013026
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Potential therapeutics for SARS R-HSA-9679191
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPases Activate ROCKs R-HSA-5627117
Disease R-HSA-1643685
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
Signal Transduction R-HSA-162582
RHOBTB1 GTPase cycle R-HSA-9013422
RHOH GTPase cycle R-HSA-9013407
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
EPH-Ephrin signaling R-HSA-2682334
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Rho GTPases R-HSA-194315
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
GPCR downstream signalling R-HSA-388396
Sema4D in semaphorin signaling R-HSA-400685
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHOC GTPase cycle R-HSA-9013106
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPases Activate ROCKs R-HSA-5627117
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
G alpha (12/13) signalling events R-HSA-416482
Infectious disease R-HSA-5663205
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Sema4D in semaphorin signaling R-HSA-400685
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
RHO GTPases Activate ROCKs R-HSA-5627117
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by GPCR R-HSA-372790
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOB GTPase cycle R-HSA-9013026
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
G alpha (12/13) signalling events R-HSA-416482
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
Axon guidance R-HSA-422475
EPHB-mediated forward signaling R-HSA-3928662
SARS-CoV Infections R-HSA-9679506
GPCR downstream signalling R-HSA-388396
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPase cycle R-HSA-9012999
RHOA GTPase cycle R-HSA-8980692
GPCR downstream signalling R-HSA-388396
Nervous system development R-HSA-9675108
VEGFA-VEGFR2 Pathway R-HSA-4420097
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
RHOBTB1 GTPase cycle R-HSA-9013422
EPH-Ephrin signaling R-HSA-2682334
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
RHOB GTPase cycle R-HSA-9013026
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOH GTPase cycle R-HSA-9013407
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOC GTPase cycle R-HSA-9013106
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
RHOC GTPase cycle R-HSA-9013106
RHOBTB GTPase Cycle R-HSA-9706574
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
Nervous system development R-HSA-9675108
RHOBTB1 GTPase cycle R-HSA-9013422
RHOA GTPase cycle R-HSA-8980692
G alpha (12/13) signalling events R-HSA-416482
GPCR downstream signalling R-HSA-388396
Signaling by Rho GTPases R-HSA-194315
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Potential therapeutics for SARS R-HSA-9679191
RHO GTPases Activate ROCKs R-HSA-5627117
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Semaphorin interactions R-HSA-373755

Expression Atlas ENSG00000134318
NCBI gene (formerly Entrezgene) 9475
GeneCards 10252
HGNC Symbol HGNC:10252
MIM gene 604002
UniProtKB Gene Name O75116
WikiGene 9475
Gene: CYP11B1
Ensembl ID : ENSG00000160882
Description: cytochrome P450 family 11 subfamily B member 1
Gene Synonyms: CPN1,CYP11B,FHI,P450C11
2 APIs:
40 Possible Orthologues:

Glucocorticoid biosynthesis R-HSA-194002
Defective CYP11B1 causes AH4 R-HSA-5579017
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Disease R-HSA-1643685
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Endogenous sterols R-HSA-211976
Diseases of metabolism R-HSA-5668914
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of steroids R-HSA-8957322
Metabolism of steroid hormones R-HSA-196071
Metabolism R-HSA-1430728
Diseases of metabolism R-HSA-5668914
Glucocorticoid biosynthesis R-HSA-194002
Biological oxidations R-HSA-211859
Endogenous sterols R-HSA-211976
Disease R-HSA-1643685
Metabolism of lipids R-HSA-556833
Cytochrome P450 - arranged by substrate type R-HSA-211897
Defective CYP11B1 causes AH4 R-HSA-5579017
Defective CYP11B1 causes AH4 R-HSA-5579017
Cytochrome P450 - arranged by substrate type R-HSA-211897
Phase I - Functionalization of compounds R-HSA-211945
Diseases of metabolism R-HSA-5668914
Glucocorticoid biosynthesis R-HSA-194002
Endogenous sterols R-HSA-211976
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of steroid hormones R-HSA-196071
Metabolism of lipids R-HSA-556833

Expression Atlas ENSG00000160882
NCBI gene (formerly Entrezgene) 1584
GeneCards 2591
HGNC Symbol HGNC:2591
MIM gene 610613
MIM morbid 202010
UniProtKB Gene Name Q4VAR0
WikiGene 1584
Gene: BRAF
Ensembl ID : ENSG00000157764
Description: B-Raf proto-oncogene, serine/threonine kinase
Gene Synonyms: BRAF-1,BRAF1
14 APIs:
211 Possible Orthologues:

Oncogenic MAPK signaling R-HSA-6802957
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF activation R-HSA-5673000
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by RAS mutants R-HSA-6802949
Oncogenic MAPK signaling R-HSA-6802957
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by FGFR4 R-HSA-5654743
Negative feedback regulation of MAPK pathway R-HSA-5674499
Disease R-HSA-1643685
Negative regulation of MAPK pathway R-HSA-5675221
MAPK family signaling cascades R-HSA-5683057
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by NTRK1 (TRKA) R-HSA-187037
Negative regulation of FGFR1 signaling R-HSA-5654726
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
ARMS-mediated activation R-HSA-170984
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR3 R-HSA-5654741
Negative regulation of FGFR2 signaling R-HSA-5654727
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by FGFR1 R-HSA-5654736
Frs2-mediated activation R-HSA-170968
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by FGFR R-HSA-190236
Signalling to ERKs R-HSA-187687
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAP2K and MAPK activation R-HSA-5674135
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR2 R-HSA-5654738
Signaling by NTRKs R-HSA-166520
Signal Transduction R-HSA-162582
Signaling by RAF1 mutants R-HSA-9656223
RAF/MAP kinase cascade R-HSA-5673001
Prolonged ERK activation events R-HSA-169893
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR3 signaling R-HSA-5654732
Negative regulation of MAPK pathway R-HSA-5675221
Disease R-HSA-1643685
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 R-HSA-5654738
Signaling by RAS mutants R-HSA-6802949
RAF activation R-HSA-5673000
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by FGFR1 R-HSA-5654736
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Negative feedback regulation of MAPK pathway R-HSA-5674499
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by NTRK1 (TRKA) R-HSA-187037
Frs2-mediated activation R-HSA-170968
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signalling to p38 via RIT and RIN R-HSA-187706
Signalling to ERKs R-HSA-187687
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by FGFR4 R-HSA-5654743
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by FGFR R-HSA-190236
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR4 signaling R-HSA-5654733
ARMS-mediated activation R-HSA-170984
Negative regulation of FGFR1 signaling R-HSA-5654726
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAP2K and MAPK activation R-HSA-5674135
Signal Transduction R-HSA-162582
Signaling by FGFR3 R-HSA-5654741
Signaling downstream of RAS mutants R-HSA-9649948
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by RAF1 mutants R-HSA-9656223
RAF/MAP kinase cascade R-HSA-5673001
ARMS-mediated activation R-HSA-170984
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR R-HSA-190236
Disease R-HSA-1643685
Frs2-mediated activation R-HSA-170968
RAF activation R-HSA-5673000
Signaling by RAS mutants R-HSA-6802949
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by FGFR4 R-HSA-5654743
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by FGFR3 R-HSA-5654741
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAPK family signaling cascades R-HSA-5683057
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by NTRK1 (TRKA) R-HSA-187037
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR1 R-HSA-5654736
Signaling by NTRKs R-HSA-166520
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Negative regulation of FGFR4 signaling R-HSA-5654733
Prolonged ERK activation events R-HSA-169893
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR2 R-HSA-5654738
Oncogenic MAPK signaling R-HSA-6802957
Signalling to p38 via RIT and RIN R-HSA-187706
Signal Transduction R-HSA-162582
Signalling to ERKs R-HSA-187687
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF activation R-HSA-5673000
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR4 R-HSA-5654743
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signalling to ERKs R-HSA-187687
ARMS-mediated activation R-HSA-170984
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Signaling by NTRKs R-HSA-166520
Signaling by FGFR3 R-HSA-5654741
Oncogenic MAPK signaling R-HSA-6802957
MAPK family signaling cascades R-HSA-5683057
MAP2K and MAPK activation R-HSA-5674135
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of FGFR2 signaling R-HSA-5654727
Frs2-mediated activation R-HSA-170968
Disease R-HSA-1643685
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Spry regulation of FGF signaling R-HSA-1295596
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by BRAF and RAF1 fusions R-HSA-6802952
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling downstream of RAS mutants R-HSA-9649948
Prolonged ERK activation events R-HSA-169893
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by RAS mutants R-HSA-6802949
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR1 signaling R-HSA-5654726
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of FGFR3 signaling R-HSA-5654732
RAF/MAP kinase cascade R-HSA-5673001
Negative feedback regulation of MAPK pathway R-HSA-5674499
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
ARMS-mediated activation R-HSA-170984
RAF activation R-HSA-5673000
Signaling by FGFR1 R-HSA-5654736
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Spry regulation of FGF signaling R-HSA-1295596
Prolonged ERK activation events R-HSA-169893
Signalling to ERKs R-HSA-187687
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAS mutants R-HSA-6802949
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by NTRKs R-HSA-166520
Signaling by RAF1 mutants R-HSA-9656223
MAP2K and MAPK activation R-HSA-5674135
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR R-HSA-190236
Signaling by NTRK1 (TRKA) R-HSA-187037
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Frs2-mediated activation R-HSA-170968
Signaling by FGFR3 R-HSA-5654741
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by MRAS-complex mutants R-HSA-9660537
Negative regulation of FGFR4 signaling R-HSA-5654733
RAF/MAP kinase cascade R-HSA-5673001
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
Signaling by FGFR1 R-HSA-5654736
Signaling downstream of RAS mutants R-HSA-9649948
Spry regulation of FGF signaling R-HSA-1295596
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of FGFR4 signaling R-HSA-5654733
ARMS-mediated activation R-HSA-170984
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by RAS mutants R-HSA-6802949
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Disease R-HSA-1643685
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
MAP2K and MAPK activation R-HSA-5674135
Signalling to p38 via RIT and RIN R-HSA-187706
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR3 R-HSA-5654741
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR R-HSA-190236
Signaling by NTRK1 (TRKA) R-HSA-187037
Negative regulation of FGFR3 signaling R-HSA-5654732
Negative feedback regulation of MAPK pathway R-HSA-5674499
Frs2-mediated activation R-HSA-170968
Signaling by FGFR4 R-HSA-5654743
Signaling by MRAS-complex mutants R-HSA-9660537
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
MAPK family signaling cascades R-HSA-5683057
RAF activation R-HSA-5673000
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Signalling to ERKs R-HSA-187687
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR4 signaling R-HSA-5654733
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by FGFR1 R-HSA-5654736
ARMS-mediated activation R-HSA-170984
Negative regulation of MAPK pathway R-HSA-5675221
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by FGFR R-HSA-190236
Signaling by FGFR3 R-HSA-5654741
Negative regulation of FGFR3 signaling R-HSA-5654732
Frs2-mediated activation R-HSA-170968
Signal Transduction R-HSA-162582
Signaling by FGFR4 R-HSA-5654743
Disease R-HSA-1643685
Signaling by FGFR2 R-HSA-5654738
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR1 signaling R-HSA-5654726
RAF activation R-HSA-5673000
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF/MAP kinase cascade R-HSA-5673001
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling downstream of RAS mutants R-HSA-9649948
MAP2K and MAPK activation R-HSA-5674135
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Spry regulation of FGF signaling R-HSA-1295596
Signaling by NTRK1 (TRKA) R-HSA-187037
Prolonged ERK activation events R-HSA-169893
Signaling by RAS mutants R-HSA-6802949
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
RAF activation R-HSA-5673000
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR1 signaling R-HSA-5654726
Oncogenic MAPK signaling R-HSA-6802957
Signaling by NTRK1 (TRKA) R-HSA-187037
MAPK family signaling cascades R-HSA-5683057
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling by FGFR3 R-HSA-5654741
Signaling by RAF1 mutants R-HSA-9656223
Signaling by NTRKs R-HSA-166520
Signalling to p38 via RIT and RIN R-HSA-187706
Prolonged ERK activation events R-HSA-169893
Signalling to ERKs R-HSA-187687
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling downstream of RAS mutants R-HSA-9649948
Frs2-mediated activation R-HSA-170968
RAF/MAP kinase cascade R-HSA-5673001
Signaling by BRAF and RAF1 fusions R-HSA-6802952
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by FGFR2 R-HSA-5654738
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by MRAS-complex mutants R-HSA-9660537
ARMS-mediated activation R-HSA-170984
Negative regulation of FGFR4 signaling R-HSA-5654733
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
Signaling by FGFR4 R-HSA-5654743
Disease R-HSA-1643685
Signaling by FGFR1 R-HSA-5654736
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR3 signaling R-HSA-5654732
Spry regulation of FGF signaling R-HSA-1295596
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by RAF1 mutants R-HSA-9656223
Signaling by FGFR R-HSA-190236
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
ARMS-mediated activation R-HSA-170984
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of FGFR2 signaling R-HSA-5654727
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by RAS mutants R-HSA-6802949
Signaling by FGFR2 R-HSA-5654738
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Frs2-mediated activation R-HSA-170968
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by FGFR3 R-HSA-5654741
Disease R-HSA-1643685
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NTRK1 (TRKA) R-HSA-187037
RAF activation R-HSA-5673000
Negative feedback regulation of MAPK pathway R-HSA-5674499
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signalling to ERKs R-HSA-187687
Negative regulation of FGFR3 signaling R-HSA-5654732
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR1 R-HSA-5654736
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by MRAS-complex mutants R-HSA-9660537
Oncogenic MAPK signaling R-HSA-6802957
Negative regulation of MAPK pathway R-HSA-5675221
RAF/MAP kinase cascade R-HSA-5673001
Spry regulation of FGF signaling R-HSA-1295596
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signal Transduction R-HSA-162582
Negative regulation of FGFR1 signaling R-HSA-5654726
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR4 R-HSA-5654743
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Signaling by FGFR4 R-HSA-5654743
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by FGFR2 R-HSA-5654738
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR1 R-HSA-5654736
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Signaling by RAF1 mutants R-HSA-9656223
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Prolonged ERK activation events R-HSA-169893
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Negative regulation of MAPK pathway R-HSA-5675221
ARMS-mediated activation R-HSA-170984
Signalling to ERKs R-HSA-187687
Signaling by MRAS-complex mutants R-HSA-9660537
Signal Transduction R-HSA-162582
Signaling by FGFR3 R-HSA-5654741
Signaling downstream of RAS mutants R-HSA-9649948
RAF activation R-HSA-5673000
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by NTRKs R-HSA-166520
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative regulation of FGFR3 signaling R-HSA-5654732
Frs2-mediated activation R-HSA-170968
Negative regulation of FGFR4 signaling R-HSA-5654733
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by BRAF and RAF1 fusions R-HSA-6802952
MAP2K and MAPK activation R-HSA-5674135
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946

Expression Atlas ENSG00000157764
LRG display in Ensembl gene LRG_299
NCBI gene (formerly Entrezgene) 673
GeneCards 1097
HGNC Symbol HGNC:1097
MIM gene 164757
MIM morbid 613707
UniProtKB Gene Name P15056
WikiGene 673
Gene: TBXAS1
Ensembl ID : ENSG00000059377
Description: thromboxane A synthase 1
Gene Synonyms: CYP5,CYP5A1,THAS,TS,TXAS,TXS
3 APIs:
219 Possible Orthologues:

Phase I - Functionalization of compounds R-HSA-211945
Arachidonic acid metabolism R-HSA-2142753
Disease R-HSA-1643685
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Biological oxidations R-HSA-211859
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Fatty acid metabolism R-HSA-8978868
Diseases of metabolism R-HSA-5668914
Defective TBXAS1 causes GHDD R-HSA-5579032
Eicosanoids R-HSA-211979
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Arachidonic acid metabolism R-HSA-2142753
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Disease R-HSA-1643685
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Cytochrome P450 - arranged by substrate type R-HSA-211897
Eicosanoids R-HSA-211979
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Defective TBXAS1 causes GHDD R-HSA-5579032
Diseases of metabolism R-HSA-5668914
Fatty acid metabolism R-HSA-8978868
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Defective TBXAS1 causes GHDD R-HSA-5579032
Phase I - Functionalization of compounds R-HSA-211945
Eicosanoids R-HSA-211979
Metabolism of lipids R-HSA-556833
Diseases of metabolism R-HSA-5668914
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Arachidonic acid metabolism R-HSA-2142753
Cytochrome P450 - arranged by substrate type R-HSA-211897
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Diseases of metabolism R-HSA-5668914
Metabolism of lipids R-HSA-556833
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Biological oxidations R-HSA-211859
Fatty acid metabolism R-HSA-8978868
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Defective TBXAS1 causes GHDD R-HSA-5579032
Phase I - Functionalization of compounds R-HSA-211945
Eicosanoids R-HSA-211979
Arachidonic acid metabolism R-HSA-2142753
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Eicosanoids R-HSA-211979
Cytochrome P450 - arranged by substrate type R-HSA-211897
Arachidonic acid metabolism R-HSA-2142753
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Fatty acid metabolism R-HSA-8978868
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Metabolism of lipids R-HSA-556833
Defective TBXAS1 causes GHDD R-HSA-5579032
Diseases of metabolism R-HSA-5668914
Fatty acid metabolism R-HSA-8978868
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Defective TBXAS1 causes GHDD R-HSA-5579032
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Eicosanoids R-HSA-211979
Disease R-HSA-1643685
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Arachidonic acid metabolism R-HSA-2142753
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Defective TBXAS1 causes GHDD R-HSA-5579032
Eicosanoids R-HSA-211979
Diseases of metabolism R-HSA-5668914
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Cytochrome P450 - arranged by substrate type R-HSA-211897
Fatty acid metabolism R-HSA-8978868
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Arachidonic acid metabolism R-HSA-2142753
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Defective TBXAS1 causes GHDD R-HSA-5579032
Metabolism R-HSA-1430728
Diseases of metabolism R-HSA-5668914
Phase I - Functionalization of compounds R-HSA-211945
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Disease R-HSA-1643685
Metabolism of lipids R-HSA-556833
Cytochrome P450 - arranged by substrate type R-HSA-211897
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Biological oxidations R-HSA-211859
Eicosanoids R-HSA-211979
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Metabolism of lipids R-HSA-556833
Eicosanoids R-HSA-211979
Diseases of metabolism R-HSA-5668914
Arachidonic acid metabolism R-HSA-2142753
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Defective TBXAS1 causes GHDD R-HSA-5579032
Biological oxidations R-HSA-211859
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Fatty acid metabolism R-HSA-8978868
Cytochrome P450 - arranged by substrate type R-HSA-211897
Biological oxidations R-HSA-211859
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123
Fatty acid metabolism R-HSA-8978868
Arachidonic acid metabolism R-HSA-2142753
Defective TBXAS1 causes GHDD R-HSA-5579032
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Metabolism R-HSA-1430728
Eicosanoids R-HSA-211979
Phase I - Functionalization of compounds R-HSA-211945
Metabolic disorders of biological oxidation enzymes R-HSA-5579029
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of lipids R-HSA-556833

Expression Atlas ENSG00000059377
LRG display in Ensembl gene LRG_579
NCBI gene (formerly Entrezgene) 6916
GeneCards 11609
HGNC Symbol HGNC:11609
MIM gene 274180
MIM morbid 231095
UniProtKB Gene Name P24557
WikiGene 6916
Ensembl ID : ENSG00000089022
Description: MAPK activated protein kinase 5
Gene Synonyms: MK5,PRAK
1 APIs:
179 Possible Orthologues:

Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity R-HSA-5633007
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583

Expression Atlas ENSG00000089022
NCBI gene (formerly Entrezgene) 8550
GeneCards 6889
HGNC Symbol HGNC:6889
MIM gene 606723
MIM morbid 619869
UniProtKB Gene Name R4GN93
WikiGene 8550
Gene: CA13
Ensembl ID : ENSG00000185015
Description: carbonic anhydrase 13
Gene Synonyms: CAXIII,FLJ37995,MGC59868
2 APIs:
291 Possible Orthologues:

Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Reversible hydration of carbon dioxide R-HSA-1475029

Expression Atlas ENSG00000185015
NCBI gene (formerly Entrezgene) 377677
GeneCards 14914
HGNC Symbol HGNC:14914
MIM gene 611436
UniProtKB Gene Name Q8N1Q1
WikiGene 377677