Ensembl ID : ENSG00000089022
Description: MAPK activated protein kinase 5
Gene Synonyms: MK5,PRAK
1 APIs:
179 Possible Orthologues:

Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
MAPK6/MAPK4 signaling R-HSA-5687128
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity R-HSA-5633007
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stress R-HSA-2262752
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
Oxidative Stress Induced Senescence R-HSA-2559580
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Signal Transduction R-HSA-162582
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
MAPK family signaling cascades R-HSA-5683057
Transcriptional Regulation by TP53 R-HSA-3700989
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
MAPK6/MAPK4 signaling R-HSA-5687128
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
MAPK family signaling cascades R-HSA-5683057
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of TP53 Activity R-HSA-5633007
Generic Transcription Pathway R-HSA-212436
MAPK family signaling cascades R-HSA-5683057
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
MAPK6/MAPK4 signaling R-HSA-5687128
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
MAPK family signaling cascades R-HSA-5683057
Signal Transduction R-HSA-162582
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by TP53 R-HSA-3700989
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583

Expression Atlas ENSG00000089022
NCBI gene (formerly Entrezgene) 8550
GeneCards 6889
HGNC Symbol HGNC:6889
MIM gene 606723
MIM morbid 619869
UniProtKB Gene Name R4GN93
WikiGene 8550
Gene: KDR
Ensembl ID : ENSG00000128052
Description: kinase insert domain receptor
Gene Synonyms: CD309,FLK1,VEGFR,VEGFR2
71 APIs:
199 Possible Orthologues:

VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
VEGFA-VEGFR2 Pathway R-HSA-4420097
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Integrin cell surface interactions R-HSA-216083
Signaling by PDGFR in disease R-HSA-9671555
Integrin cell surface interactions R-HSA-216083
VEGFR2 mediated cell proliferation R-HSA-5218921
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
VEGF ligand-receptor interactions R-HSA-194313
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by VEGF R-HSA-194138
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by VEGF R-HSA-194138
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Signaling by PDGFR in disease R-HSA-9671555
Signal Transduction R-HSA-162582
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
Integrin cell surface interactions R-HSA-216083
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signal Transduction R-HSA-162582
Signaling by PDGFR in disease R-HSA-9671555
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Integrin cell surface interactions R-HSA-216083
Disease R-HSA-1643685
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGFR2 mediated cell proliferation R-HSA-5218921
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by VEGF R-HSA-194138
Extracellular matrix organization R-HSA-1474244
Signaling by VEGF R-HSA-194138
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGF ligand-receptor interactions R-HSA-194313
Signal Transduction R-HSA-162582
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Signaling by PDGFR in disease R-HSA-9671555
Extracellular matrix organization R-HSA-1474244
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Disease R-HSA-1643685
Integrin cell surface interactions R-HSA-216083
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated cell proliferation R-HSA-5218921
Extracellular matrix organization R-HSA-1474244
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by VEGF R-HSA-194138
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Integrin cell surface interactions R-HSA-216083
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by PDGFR in disease R-HSA-9671555
VEGF ligand-receptor interactions R-HSA-194313
Signaling by VEGF R-HSA-194138
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
VEGFR2 mediated cell proliferation R-HSA-5218921
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
VEGFA-VEGFR2 Pathway R-HSA-4420097
Extracellular matrix organization R-HSA-1474244
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
VEGF ligand-receptor interactions R-HSA-194313
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
VEGFR2 mediated cell proliferation R-HSA-5218921
Integrin cell surface interactions R-HSA-216083
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by VEGF R-HSA-194138
Extracellular matrix organization R-HSA-1474244
Signaling by PDGFR in disease R-HSA-9671555
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
VEGFA-VEGFR2 Pathway R-HSA-4420097
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFR2 mediated cell proliferation R-HSA-5218921
Neurophilin interactions with VEGF and VEGFR R-HSA-194306
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768
Signaling by PDGFR in disease R-HSA-9671555
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by VEGF R-HSA-194138
Integrin cell surface interactions R-HSA-216083
VEGF ligand-receptor interactions R-HSA-194313
Extracellular matrix organization R-HSA-1474244
Disease R-HSA-1643685

Expression Atlas ENSG00000128052
LRG display in Ensembl gene LRG_1198
NCBI gene (formerly Entrezgene) 3791
GeneCards 6307
HGNC Symbol HGNC:6307
MIM gene 191306
MIM morbid 602089
UniProtKB Gene Name P35968
WikiGene 3791
Gene: TPH1
Ensembl ID : ENSG00000129167
Description: tryptophan hydroxylase 1
Gene Synonyms: TPH,TPRH
1 APIs:
257 Possible Orthologues:

Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
NGF-stimulated transcription R-HSA-9031628
Serotonin and melatonin biosynthesis R-HSA-209931
Signaling by NTRKs R-HSA-166520
Metabolism of amine-derived hormones R-HSA-209776
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRKs R-HSA-166520
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Metabolism of amine-derived hormones R-HSA-209776
Serotonin and melatonin biosynthesis R-HSA-209931
NGF-stimulated transcription R-HSA-9031628
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRKs R-HSA-166520
Metabolism of amine-derived hormones R-HSA-209776
Metabolism R-HSA-1430728
Serotonin and melatonin biosynthesis R-HSA-209931
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
NGF-stimulated transcription R-HSA-9031628
Serotonin and melatonin biosynthesis R-HSA-209931
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Metabolism of amine-derived hormones R-HSA-209776
Signaling by NTRKs R-HSA-166520
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
NGF-stimulated transcription R-HSA-9031628
Metabolism R-HSA-1430728
Metabolism of amine-derived hormones R-HSA-209776
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signal Transduction R-HSA-162582
NGF-stimulated transcription R-HSA-9031628
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NTRK1 (TRKA) R-HSA-187037
Serotonin and melatonin biosynthesis R-HSA-209931
Signaling by NTRKs R-HSA-166520
NGF-stimulated transcription R-HSA-9031628
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of amine-derived hormones R-HSA-209776
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Serotonin and melatonin biosynthesis R-HSA-209931
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism R-HSA-1430728
Serotonin and melatonin biosynthesis R-HSA-209931
NGF-stimulated transcription R-HSA-9031628
Metabolism of amine-derived hormones R-HSA-209776
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism of amino acids and derivatives R-HSA-71291
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRKs R-HSA-166520
Signal Transduction R-HSA-162582
Metabolism R-HSA-1430728
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Serotonin and melatonin biosynthesis R-HSA-209931
Metabolism of amine-derived hormones R-HSA-209776
Signaling by NTRK1 (TRKA) R-HSA-187037
Serotonin and melatonin biosynthesis R-HSA-209931
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism of amine-derived hormones R-HSA-209776
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism of amino acids and derivatives R-HSA-71291
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRKs R-HSA-166520
Metabolism R-HSA-1430728
Signaling by NTRKs R-HSA-166520
Serotonin and melatonin biosynthesis R-HSA-209931
Signaling by NTRK1 (TRKA) R-HSA-187037
Metabolism of amino acids and derivatives R-HSA-71291
Metabolism of amine-derived hormones R-HSA-209776
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
NGF-stimulated transcription R-HSA-9031628
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Metabolism R-HSA-1430728
Metabolism of amine-derived hormones R-HSA-209776
Serotonin and melatonin biosynthesis R-HSA-209931
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRKs R-HSA-166520
NGF-stimulated transcription R-HSA-9031628
Signal Transduction R-HSA-162582
Metabolism of amino acids and derivatives R-HSA-71291
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Receptor Tyrosine Kinases R-HSA-9006934

Expression Atlas ENSG00000129167
NCBI gene (formerly Entrezgene) 7166
GeneCards 12008
HGNC Symbol HGNC:12008
MIM gene 191060
UniProtKB Gene Name P17752
WikiGene 7166
Gene: INSR
Ensembl ID : ENSG00000171105
Description: insulin receptor
Gene Synonyms: CD220
36 APIs:
290 Possible Orthologues:

Signaling by Insulin receptor R-HSA-74752
PIP3 activates AKT signaling R-HSA-1257604
IRS activation R-HSA-74713
Signal attenuation R-HSA-74749
Insulin receptor recycling R-HSA-77387
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor recycling R-HSA-77387
IRS activation R-HSA-74713
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Insulin receptor signalling cascade R-HSA-74751
Signaling by Insulin receptor R-HSA-74752
Signal Transduction R-HSA-162582
Insulin receptor recycling R-HSA-77387
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal attenuation R-HSA-74749
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Negative regulation of the PI3K/AKT network R-HSA-199418
IRS activation R-HSA-74713
Insulin receptor signalling cascade R-HSA-74751
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
IRS activation R-HSA-74713
Negative regulation of the PI3K/AKT network R-HSA-199418
Insulin receptor recycling R-HSA-77387
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor recycling R-HSA-77387
Signal attenuation R-HSA-74749
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Insulin receptor R-HSA-74752
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Intracellular signaling by second messengers R-HSA-9006925
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
IRS activation R-HSA-74713
IRS activation R-HSA-74713
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Insulin receptor R-HSA-74752
Insulin receptor recycling R-HSA-77387
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal attenuation R-HSA-74749
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
Signal attenuation R-HSA-74749
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
IRS activation R-HSA-74713
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor recycling R-HSA-77387
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Signal Transduction R-HSA-162582
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal attenuation R-HSA-74749
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
IRS activation R-HSA-74713
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Insulin receptor R-HSA-74752
Insulin receptor recycling R-HSA-77387
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal attenuation R-HSA-74749
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PIP3 activates AKT signaling R-HSA-1257604
Insulin receptor signalling cascade R-HSA-74751
Intracellular signaling by second messengers R-HSA-9006925
Signal Transduction R-HSA-162582
Insulin receptor recycling R-HSA-77387
IRS activation R-HSA-74713
Signaling by Insulin receptor R-HSA-74752

Expression Atlas ENSG00000171105
NCBI gene (formerly Entrezgene) 3643
GeneCards 6091
HGNC Symbol HGNC:6091
MIM gene 147670
MIM morbid 610549
UniProtKB Gene Name P06213
WikiGene 3643
Gene: ATP1A1
Ensembl ID : ENSG00000163399
Description: ATPase Na+/K+ transporting subunit alpha 1
Gene Synonyms:
6 APIs:
328 Possible Orthologues:

Cardiac conduction R-HSA-5576891
Infectious disease R-HSA-5663205
Transport of small molecules R-HSA-382551
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
Disease R-HSA-1643685
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
SARS-CoV Infections R-HSA-9679506
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Ion transport by P-type ATPases R-HSA-936837
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Cardiac conduction R-HSA-5576891
Cardiac conduction R-HSA-5576891
Ion channel transport R-HSA-983712
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Infectious disease R-HSA-5663205
Ion homeostasis R-HSA-5578775
Ion homeostasis R-HSA-5578775
Transport of small molecules R-HSA-382551
Cardiac conduction R-HSA-5576891
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Potential therapeutics for SARS R-HSA-9679191
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Transport of small molecules R-HSA-382551
Ion channel transport R-HSA-983712
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Cardiac conduction R-HSA-5576891
Ion channel transport R-HSA-983712
Ion transport by P-type ATPases R-HSA-936837
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Ion transport by P-type ATPases R-HSA-936837
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Ion homeostasis R-HSA-5578775
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Ion channel transport R-HSA-983712
Muscle contraction R-HSA-397014
SARS-CoV Infections R-HSA-9679506
Ion transport by P-type ATPases R-HSA-936837
Transport of small molecules R-HSA-382551
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Ion transport by P-type ATPases R-HSA-936837
SARS-CoV Infections R-HSA-9679506
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
Ion channel transport R-HSA-983712
Transport of small molecules R-HSA-382551
Infectious disease R-HSA-5663205
Ion transport by P-type ATPases R-HSA-936837
Ion channel transport R-HSA-983712
Ion homeostasis R-HSA-5578775
Cardiac conduction R-HSA-5576891
Disease R-HSA-1643685
SARS-CoV Infections R-HSA-9679506
Transport of small molecules R-HSA-382551
Muscle contraction R-HSA-397014
Potential therapeutics for SARS R-HSA-9679191
Transport of small molecules R-HSA-382551
Potential therapeutics for SARS R-HSA-9679191
Cardiac conduction R-HSA-5576891
Ion homeostasis R-HSA-5578775
SARS-CoV Infections R-HSA-9679506
Ion channel transport R-HSA-983712
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Muscle contraction R-HSA-397014
Ion transport by P-type ATPases R-HSA-936837

Expression Atlas ENSG00000163399
NCBI gene (formerly Entrezgene) 476
GeneCards 799
HGNC Symbol HGNC:799
MIM gene 182310
MIM morbid 618314
UniProtKB Gene Name Q5TC05
WikiGene 476
Gene: INPP5D
Ensembl ID : ENSG00000168918
Description: inositol polyphosphate-5-phosphatase D
Gene Synonyms: HP51CN,SHIP,SHIP1
1 APIs:
214 Possible Orthologues:

Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Phospholipid metabolism R-HSA-1483257
Interleukin receptor SHC signaling R-HSA-912526
Hemostasis R-HSA-109582
TCR signaling R-HSA-202403
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Interleukins R-HSA-449147
Cell surface interactions at the vascular wall R-HSA-202733
Metabolism R-HSA-1430728
Inositol phosphate metabolism R-HSA-1483249
Interleukin-2 family signaling R-HSA-451927
Cytokine Signaling in Immune system R-HSA-1280215
PECAM1 interactions R-HSA-210990
PI Metabolism R-HSA-1483255
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Metabolism of lipids R-HSA-556833
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Phospholipid metabolism R-HSA-1483257
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Metabolism of lipids R-HSA-556833
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Interleukin-2 family signaling R-HSA-451927
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PECAM1 interactions R-HSA-210990
PI Metabolism R-HSA-1483255
Interleukin receptor SHC signaling R-HSA-912526
TCR signaling R-HSA-202403
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
Cell surface interactions at the vascular wall R-HSA-202733
Inositol phosphate metabolism R-HSA-1483249
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Hemostasis R-HSA-109582
Hemostasis R-HSA-109582
Cell surface interactions at the vascular wall R-HSA-202733
TCR signaling R-HSA-202403
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Inositol phosphate metabolism R-HSA-1483249
Interleukin-2 family signaling R-HSA-451927
Adaptive Immune System R-HSA-1280218
Interleukin receptor SHC signaling R-HSA-912526
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Cytokine Signaling in Immune system R-HSA-1280215
PI Metabolism R-HSA-1483255
PECAM1 interactions R-HSA-210990
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Signaling by Interleukins R-HSA-449147
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Phospholipid metabolism R-HSA-1483257
PECAM1 interactions R-HSA-210990
Interleukin-2 family signaling R-HSA-451927
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
TCR signaling R-HSA-202403
Hemostasis R-HSA-109582
Metabolism R-HSA-1430728
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Immune System R-HSA-168256
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Adaptive Immune System R-HSA-1280218
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Phospholipid metabolism R-HSA-1483257
Signaling by Interleukins R-HSA-449147
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Inositol phosphate metabolism R-HSA-1483249
Metabolism of lipids R-HSA-556833
Interleukin receptor SHC signaling R-HSA-912526
Cell surface interactions at the vascular wall R-HSA-202733
PI Metabolism R-HSA-1483255
Cell surface interactions at the vascular wall R-HSA-202733
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PECAM1 interactions R-HSA-210990
Interleukin-2 family signaling R-HSA-451927
PI Metabolism R-HSA-1483255
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
TCR signaling R-HSA-202403
Immune System R-HSA-168256
Phospholipid metabolism R-HSA-1483257
Hemostasis R-HSA-109582
Interleukin receptor SHC signaling R-HSA-912526
Metabolism of lipids R-HSA-556833
Inositol phosphate metabolism R-HSA-1483249
Downstream TCR signaling R-HSA-202424
Metabolism R-HSA-1430728
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Adaptive Immune System R-HSA-1280218
Signaling by Interleukins R-HSA-449147
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Cytokine Signaling in Immune system R-HSA-1280215
Hemostasis R-HSA-109582
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by Interleukins R-HSA-449147
Metabolism of lipids R-HSA-556833
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PECAM1 interactions R-HSA-210990
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Interleukin receptor SHC signaling R-HSA-912526
Cell surface interactions at the vascular wall R-HSA-202733
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
TCR signaling R-HSA-202403
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
Interleukin-2 family signaling R-HSA-451927
Inositol phosphate metabolism R-HSA-1483249
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 family signaling R-HSA-451927
Interleukin receptor SHC signaling R-HSA-912526
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Adaptive Immune System R-HSA-1280218
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Immune System R-HSA-168256
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Inositol phosphate metabolism R-HSA-1483249
Hemostasis R-HSA-109582
Cell surface interactions at the vascular wall R-HSA-202733
Cytokine Signaling in Immune system R-HSA-1280215
PI Metabolism R-HSA-1483255
Phospholipid metabolism R-HSA-1483257
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
PECAM1 interactions R-HSA-210990
Signaling by Interleukins R-HSA-449147
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
PECAM1 interactions R-HSA-210990
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 family signaling R-HSA-451927
Adaptive Immune System R-HSA-1280218
Interleukin receptor SHC signaling R-HSA-912526
Cell surface interactions at the vascular wall R-HSA-202733
TCR signaling R-HSA-202403
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Inositol phosphate metabolism R-HSA-1483249
Downstream TCR signaling R-HSA-202424
Metabolism of lipids R-HSA-556833
Phospholipid metabolism R-HSA-1483257
Metabolism R-HSA-1430728
Immune System R-HSA-168256
PI Metabolism R-HSA-1483255
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Hemostasis R-HSA-109582
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Signaling by Interleukins R-HSA-449147
Interleukin-2 family signaling R-HSA-451927
TCR signaling R-HSA-202403
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Phospholipid metabolism R-HSA-1483257
PI Metabolism R-HSA-1483255
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by Interleukins R-HSA-449147
Cell surface interactions at the vascular wall R-HSA-202733
PECAM1 interactions R-HSA-210990
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Metabolism R-HSA-1430728
Interleukin receptor SHC signaling R-HSA-912526
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
Metabolism of lipids R-HSA-556833
Hemostasis R-HSA-109582
Inositol phosphate metabolism R-HSA-1483249
Adaptive Immune System R-HSA-1280218
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204
PECAM1 interactions R-HSA-210990
TCR signaling R-HSA-202403
Interleukin-2 family signaling R-HSA-451927
Downstream TCR signaling R-HSA-202424
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by Interleukins R-HSA-449147
Metabolism of lipids R-HSA-556833
Adaptive Immune System R-HSA-1280218
Hemostasis R-HSA-109582
Metabolism R-HSA-1430728
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Immune System R-HSA-168256
Phospholipid metabolism R-HSA-1483257
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin receptor SHC signaling R-HSA-912526
PI Metabolism R-HSA-1483255
Inositol phosphate metabolism R-HSA-1483249
Synthesis of PIPs at the plasma membrane R-HSA-1660499

Expression Atlas ENSG00000168918
NCBI gene (formerly Entrezgene) 3635
GeneCards 6079
HGNC Symbol HGNC:6079
MIM gene 601582
UniProtKB Gene Name Q92835
WikiGene 3635
Gene: PSMA1
Ensembl ID : ENSG00000129084
Description: proteasome 20S subunit alpha 1
Gene Synonyms: HC2,MGC14542,MGC14575,MGC14751,MGC1667,MGC21459,MGC22853,MGC23915,NU,PROS30
6 APIs:
237 Possible Orthologues:

TCF dependent signaling in response to WNT R-HSA-201681
S Phase R-HSA-69242
HIV Infection R-HSA-162906
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
Transcriptional regulation by RUNX1 R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transport of small molecules R-HSA-382551
CLEC7A (Dectin-1) signaling R-HSA-5607764
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Regulation of RUNX2 expression and activity R-HSA-8939902
Cyclin E associated events during G1/S transition R-HSA-69202
Signaling by WNT R-HSA-195721
Cellular response to hypoxia R-HSA-1234174
G1/S Transition R-HSA-69206
Switching of origins to a post-replicative state R-HSA-69052
Cell Cycle R-HSA-1640170
Metabolism of amino acids and derivatives R-HSA-71291
Neddylation R-HSA-8951664
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
S Phase R-HSA-69242
TCR signaling R-HSA-202403
MAPK family signaling cascades R-HSA-5683057
DNA Replication R-HSA-69306
Defective CFTR causes cystic fibrosis R-HSA-5678895
Mitotic Metaphase and Anaphase R-HSA-2555396
Signaling by NOTCH4 R-HSA-9013694
Interleukin-1 family signaling R-HSA-446652
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
G2/M Checkpoints R-HSA-69481
ABC transporter disorders R-HSA-5619084
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of mitotic cell cycle R-HSA-453276
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RNA Polymerase II Transcription R-HSA-73857
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Deubiquitination R-HSA-5688426
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK6/MAPK4 signaling R-HSA-5687128
Adaptive Immune System R-HSA-1280218
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing-Cross presentation R-HSA-1236975
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of RAS by GAPs R-HSA-5658442
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
RAF/MAP kinase cascade R-HSA-5673001
Axon guidance R-HSA-422475
UCH proteinases R-HSA-5689603
Degradation of beta-catenin by the destruction complex R-HSA-195253
PTEN Regulation R-HSA-6807070
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Negative regulation of NOTCH4 signaling R-HSA-9604323
Infectious disease R-HSA-5663205
ABC-family proteins mediated transport R-HSA-382556
Signaling by ROBO receptors R-HSA-376176
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cellular response to chemical stress R-HSA-9711123
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Anaphase R-HSA-68882
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
Post-translational protein modification R-HSA-597592
Signaling by Hedgehog R-HSA-5358351
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK1/MAPK3 signaling R-HSA-5684996
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
TCF dependent signaling in response to WNT R-HSA-201681
Gene expression (Transcription) R-HSA-74160
Activation of NF-kappaB in B cells R-HSA-1169091
Synthesis of DNA R-HSA-69239
Hedgehog 'off' state R-HSA-5610787
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Vpu mediated degradation of CD4 R-HSA-180534
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Hedgehog 'on' state R-HSA-5632684
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Cellular responses to stimuli R-HSA-8953897
p53-Independent DNA Damage Response R-HSA-69610
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Metabolism of polyamines R-HSA-351202
KEAP1-NFE2L2 pathway R-HSA-9755511
Degradation of GLI2 by the proteasome R-HSA-5610783
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX3 expression and activity R-HSA-8941858
Disorders of transmembrane transporters R-HSA-5619115
Programmed Cell Death R-HSA-5357801
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of Apoptosis R-HSA-169911
Transcriptional regulation by RUNX3 R-HSA-8878159
Metabolism R-HSA-1430728
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Degradation of DVL R-HSA-4641258
Class I MHC mediated antigen processing & presentation R-HSA-983169
Downstream TCR signaling R-HSA-202424
Nervous system development R-HSA-9675108
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hedgehog ligand biogenesis R-HSA-5358346
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Vif-mediated degradation of APOBEC3G R-HSA-180585
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Beta-catenin independent WNT signaling R-HSA-3858494
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
DNA Replication Pre-Initiation R-HSA-69002
Transport of small molecules R-HSA-382551
Nuclear events mediated by NFE2L2 R-HSA-9759194
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Cytokine Signaling in Immune system R-HSA-1280215
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
p53-Independent DNA Damage Response R-HSA-69610
Regulation of RAS by GAPs R-HSA-5658442
Post-translational protein modification R-HSA-597592
Cell Cycle Checkpoints R-HSA-69620
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RAF/MAP kinase cascade R-HSA-5673001
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Innate Immune System R-HSA-168249
UCH proteinases R-HSA-5689603
Signaling by WNT R-HSA-195721
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Separation of Sister Chromatids R-HSA-2467813
Cyclin E associated events during G1/S transition R-HSA-69202
Metabolism of RNA R-HSA-8953854
CLEC7A (Dectin-1) signaling R-HSA-5607764
Generic Transcription Pathway R-HSA-212436
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulation of PTEN stability and activity R-HSA-8948751
Developmental Biology R-HSA-1266738
DNA Replication R-HSA-69306
FCERI mediated NF-kB activation R-HSA-2871837
MAPK1/MAPK3 signaling R-HSA-5684996
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Deubiquitination R-HSA-5688426
Regulation of RUNX2 expression and activity R-HSA-8939902
Mitotic G2-G2/M phases R-HSA-453274
Stabilization of p53 R-HSA-69541
Activation of NF-kappaB in B cells R-HSA-1169091
Cellular response to hypoxia R-HSA-1234174
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX2 R-HSA-8878166
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Vif-mediated degradation of APOBEC3G R-HSA-180585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Apoptosis R-HSA-109581
Host Interactions of HIV factors R-HSA-162909
ER-Phagosome pathway R-HSA-1236974
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of Apoptosis R-HSA-169911
MAPK6/MAPK4 signaling R-HSA-5687128
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
M Phase R-HSA-68886
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Metabolism of polyamines R-HSA-351202
Interleukin-1 signaling R-HSA-9020702
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Ub-specific processing proteases R-HSA-5689880
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of beta-catenin by the destruction complex R-HSA-195253
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular response to chemical stress R-HSA-9711123
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
PTEN Regulation R-HSA-6807070
Hedgehog 'on' state R-HSA-5632684
RNA Polymerase II Transcription R-HSA-73857
TCR signaling R-HSA-202403
PCP/CE pathway R-HSA-4086400
NIK-->noncanonical NF-kB signaling R-HSA-5676590
ABC transporter disorders R-HSA-5619084
Axon guidance R-HSA-422475
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism R-HSA-1430728
Signaling by ROBO receptors R-HSA-376176
Antigen processing-Cross presentation R-HSA-1236975
G2/M Transition R-HSA-69275
Degradation of AXIN R-HSA-4641257
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G1 phase and G1/S transition R-HSA-453279
Asymmetric localization of PCP proteins R-HSA-4608870
G1/S Transition R-HSA-69206
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Assembly of the pre-replicative complex R-HSA-68867
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of amino acids and derivatives R-HSA-71291
Downstream TCR signaling R-HSA-202424
Hh mutants abrogate ligand secretion R-HSA-5387390
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
G2/M Checkpoints R-HSA-69481
Hedgehog ligand biogenesis R-HSA-5358346
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Degradation of DVL R-HSA-4641258
Regulation of RUNX3 expression and activity R-HSA-8941858
Signaling by Interleukins R-HSA-449147
Regulation of mitotic cell cycle R-HSA-453276
Switching of origins to a post-replicative state R-HSA-69052
Interleukin-1 family signaling R-HSA-446652
S Phase R-HSA-69242
Mitotic Anaphase R-HSA-68882
Signaling by NOTCH4 R-HSA-9013694
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Degradation of GLI2 by the proteasome R-HSA-5610783
Adaptive Immune System R-HSA-1280218
Signaling by NOTCH R-HSA-157118
Cell Cycle, Mitotic R-HSA-69278
KEAP1-NFE2L2 pathway R-HSA-9755511
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disease R-HSA-1643685
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Programmed Cell Death R-HSA-5357801
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Nervous system development R-HSA-9675108
TCF dependent signaling in response to WNT R-HSA-201681
Signal Transduction R-HSA-162582
Degradation of GLI1 by the proteasome R-HSA-5610780
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK family signaling cascades R-HSA-5683057
HIV Infection R-HSA-162906
Transcriptional regulation by RUNX1 R-HSA-8878171
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cellular responses to stimuli R-HSA-8953897
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cell Cycle R-HSA-1640170
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
S Phase R-HSA-69242
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cell Cycle, Mitotic R-HSA-69278
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Switching of origins to a post-replicative state R-HSA-69052
C-type lectin receptors (CLRs) R-HSA-5621481
Developmental Biology R-HSA-1266738
ABC-family proteins mediated transport R-HSA-382556
Regulation of mitotic cell cycle R-HSA-453276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cell Cycle R-HSA-1640170
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic G2-G2/M phases R-HSA-453274
Regulation of PTEN stability and activity R-HSA-8948751
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
ABC transporter disorders R-HSA-5619084
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
HIV Infection R-HSA-162906
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
MAPK family signaling cascades R-HSA-5683057
CLEC7A (Dectin-1) signaling R-HSA-5607764
Separation of Sister Chromatids R-HSA-2467813
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Generic Transcription Pathway R-HSA-212436
Cellular responses to stimuli R-HSA-8953897
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vpu mediated degradation of CD4 R-HSA-180534
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by NOTCH4 R-HSA-9013694
UCH proteinases R-HSA-5689603
PCP/CE pathway R-HSA-4086400
Infectious disease R-HSA-5663205
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cytokine Signaling in Immune system R-HSA-1280215
Host Interactions of HIV factors R-HSA-162909
Activation of NF-kappaB in B cells R-HSA-1169091
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hh mutants are degraded by ERAD R-HSA-5362768
Downstream TCR signaling R-HSA-202424
Signaling by Hedgehog R-HSA-5358351
Mitotic G1 phase and G1/S transition R-HSA-453279
TCF dependent signaling in response to WNT R-HSA-201681
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Degradation of beta-catenin by the destruction complex R-HSA-195253
G2/M Checkpoints R-HSA-69481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
PTEN Regulation R-HSA-6807070
Disease R-HSA-1643685
Transcriptional regulation by RUNX2 R-HSA-8878166
Mitotic Metaphase and Anaphase R-HSA-2555396
Mitotic Anaphase R-HSA-68882
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
Transport of small molecules R-HSA-382551
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication R-HSA-69306
MAPK1/MAPK3 signaling R-HSA-5684996
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Cellular response to chemical stress R-HSA-9711123
Synthesis of DNA R-HSA-69239
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Degradation of DVL R-HSA-4641258
ER-Phagosome pathway R-HSA-1236974
Hedgehog 'on' state R-HSA-5632684
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
Hedgehog 'off' state R-HSA-5610787
G1/S Transition R-HSA-69206
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Ub-specific processing proteases R-HSA-5689880
Interleukin-1 signaling R-HSA-9020702
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Transcriptional regulation by RUNX1 R-HSA-8878171
Orc1 removal from chromatin R-HSA-68949
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1 DNA Damage Response R-HSA-69563
Antigen processing-Cross presentation R-HSA-1236975
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Cell Cycle Checkpoints R-HSA-69620
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Metabolism of amino acids and derivatives R-HSA-71291
Beta-catenin independent WNT signaling R-HSA-3858494
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Assembly of the pre-replicative complex R-HSA-68867
Deubiquitination R-HSA-5688426
FCERI mediated NF-kB activation R-HSA-2871837
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RAS by GAPs R-HSA-5658442
Programmed Cell Death R-HSA-5357801
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by Interleukins R-HSA-449147
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Asymmetric localization of PCP proteins R-HSA-4608870
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of AXIN R-HSA-4641257
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
p53-Independent DNA Damage Response R-HSA-69610
G2/M Transition R-HSA-69275
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Deubiquitination R-HSA-5688426
Adaptive Immune System R-HSA-1280218
Metabolism of amino acids and derivatives R-HSA-71291
Gene expression (Transcription) R-HSA-74160
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Regulation of RAS by GAPs R-HSA-5658442
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Beta-catenin independent WNT signaling R-HSA-3858494
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Regulation of RUNX3 expression and activity R-HSA-8941858
Interleukin-1 family signaling R-HSA-446652
Hh mutants abrogate ligand secretion R-HSA-5387390
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Immune System R-HSA-168256
ABC-family proteins mediated transport R-HSA-382556
Cell Cycle, Mitotic R-HSA-69278
Mitotic Anaphase R-HSA-68882
Assembly of the pre-replicative complex R-HSA-68867
Generic Transcription Pathway R-HSA-212436
Mitotic Metaphase and Anaphase R-HSA-2555396
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Class I MHC mediated antigen processing & presentation R-HSA-983169
Neddylation R-HSA-8951664
Post-translational protein modification R-HSA-597592
Metabolism of polyamines R-HSA-351202
G1/S DNA Damage Checkpoints R-HSA-69615
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Mitotic G2-G2/M phases R-HSA-453274
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Downstream TCR signaling R-HSA-202424
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Degradation of GLI2 by the proteasome R-HSA-5610783
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Negative regulation of NOTCH4 signaling R-HSA-9604323
Cytokine Signaling in Immune system R-HSA-1280215
Nervous system development R-HSA-9675108
Degradation of GLI1 by the proteasome R-HSA-5610780
HIV Infection R-HSA-162906
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAPK family signaling cascades R-HSA-5683057
PCP/CE pathway R-HSA-4086400
Hedgehog 'off' state R-HSA-5610787
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S Transition R-HSA-69206
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
DNA Replication Pre-Initiation R-HSA-69002
Synthesis of DNA R-HSA-69239
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Switching of origins to a post-replicative state R-HSA-69052
Disease R-HSA-1643685
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cellular response to hypoxia R-HSA-1234174
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of DVL R-HSA-4641258
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Transcriptional regulation by RUNX1 R-HSA-8878171
Metabolism of RNA R-HSA-8953854
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Regulation of PTEN stability and activity R-HSA-8948751
Metabolism of proteins R-HSA-392499
Stabilization of p53 R-HSA-69541
Hh mutants are degraded by ERAD R-HSA-5362768
DNA Replication R-HSA-69306
Programmed Cell Death R-HSA-5357801
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ROBO receptors R-HSA-376176
RAF/MAP kinase cascade R-HSA-5673001
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
UCH proteinases R-HSA-5689603
Signaling by NOTCH R-HSA-157118
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX2 R-HSA-8878166
Apoptosis R-HSA-109581
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of AXIN R-HSA-4641257
Cellular response to chemical stress R-HSA-9711123
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Antigen processing-Cross presentation R-HSA-1236975
Regulation of RUNX2 expression and activity R-HSA-8939902
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism R-HSA-1430728
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of Apoptosis R-HSA-169911
Nuclear events mediated by NFE2L2 R-HSA-9759194
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Mitotic G1 phase and G1/S transition R-HSA-453279
Axon guidance R-HSA-422475
M Phase R-HSA-68886
Asymmetric localization of PCP proteins R-HSA-4608870
Cell Cycle Checkpoints R-HSA-69620
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
PTEN Regulation R-HSA-6807070
Interleukin-1 signaling R-HSA-9020702
Hedgehog ligand biogenesis R-HSA-5358346
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
Separation of Sister Chromatids R-HSA-2467813
Orc1 removal from chromatin R-HSA-68949
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
Signaling by WNT R-HSA-195721
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Neddylation R-HSA-8951664
HIV Infection R-HSA-162906
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH R-HSA-157118
Hedgehog 'off' state R-HSA-5610787
Apoptosis R-HSA-109581
Innate Immune System R-HSA-168249
Asymmetric localization of PCP proteins R-HSA-4608870
Nervous system development R-HSA-9675108
Metabolism of polyamines R-HSA-351202
p53-Dependent G1 DNA Damage Response R-HSA-69563
Generic Transcription Pathway R-HSA-212436
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Programmed Cell Death R-HSA-5357801
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
Host Interactions of HIV factors R-HSA-162909
Hedgehog 'on' state R-HSA-5632684
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX1 R-HSA-8878171
FCERI mediated NF-kB activation R-HSA-2871837
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hh mutants abrogate ligand secretion R-HSA-5387390
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Mitotic Metaphase and Anaphase R-HSA-2555396
Transport of small molecules R-HSA-382551
Immune System R-HSA-168256
Disorders of transmembrane transporters R-HSA-5619115
DNA Replication Pre-Initiation R-HSA-69002
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Cellular response to hypoxia R-HSA-1234174
RNA Polymerase II Transcription R-HSA-73857
Ub-specific processing proteases R-HSA-5689880
Disease R-HSA-1643685
M Phase R-HSA-68886
Degradation of DVL R-HSA-4641258
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of GLI2 by the proteasome R-HSA-5610783
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism R-HSA-1430728
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic Anaphase R-HSA-68882
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
Metabolism of proteins R-HSA-392499
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
G1/S Transition R-HSA-69206
Interleukin-1 family signaling R-HSA-446652
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
RAF/MAP kinase cascade R-HSA-5673001
Adaptive Immune System R-HSA-1280218
Regulation of RUNX3 expression and activity R-HSA-8941858
Intracellular signaling by second messengers R-HSA-9006925
Signaling by Interleukins R-HSA-449147
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
MAPK6/MAPK4 signaling R-HSA-5687128
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Switching of origins to a post-replicative state R-HSA-69052
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
G2/M Transition R-HSA-69275
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
KEAP1-NFE2L2 pathway R-HSA-9755511
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of RNA R-HSA-8953854
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cytokine Signaling in Immune system R-HSA-1280215
Cyclin E associated events during G1/S transition R-HSA-69202
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
ER-Phagosome pathway R-HSA-1236974
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Cellular response to chemical stress R-HSA-9711123
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK1/MAPK3 signaling R-HSA-5684996
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of AXIN R-HSA-4641257
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Transcriptional regulation by RUNX2 R-HSA-8878166
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
UCH proteinases R-HSA-5689603
PCP/CE pathway R-HSA-4086400
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle R-HSA-1640170
ABC-family proteins mediated transport R-HSA-382556
Defective CFTR causes cystic fibrosis R-HSA-5678895
Axon guidance R-HSA-422475
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
Orc1 removal from chromatin R-HSA-68949
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Downstream TCR signaling R-HSA-202424
Signaling by Hedgehog R-HSA-5358351
Hedgehog ligand biogenesis R-HSA-5358346
CLEC7A (Dectin-1) signaling R-HSA-5607764
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of GLI1 by the proteasome R-HSA-5610780
Negative regulation of NOTCH4 signaling R-HSA-9604323
Synthesis of DNA R-HSA-69239
Regulation of RAS by GAPs R-HSA-5658442
Activation of NF-kappaB in B cells R-HSA-1169091
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Separation of Sister Chromatids R-HSA-2467813
PTEN Regulation R-HSA-6807070
DNA Replication R-HSA-69306
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Antigen processing-Cross presentation R-HSA-1236975
G2/M Checkpoints R-HSA-69481
S Phase R-HSA-69242
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
PIP3 activates AKT signaling R-HSA-1257604
M Phase R-HSA-68886
G1/S Transition R-HSA-69206
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Adaptive Immune System R-HSA-1280218
Synthesis of DNA R-HSA-69239
p53-Dependent G1 DNA Damage Response R-HSA-69563
Disorders of transmembrane transporters R-HSA-5619115
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
PCP/CE pathway R-HSA-4086400
TCR signaling R-HSA-202403
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
Degradation of GLI1 by the proteasome R-HSA-5610780
Metabolism of amino acids and derivatives R-HSA-71291
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of RUNX2 expression and activity R-HSA-8939902
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle, Mitotic R-HSA-69278
Host Interactions of HIV factors R-HSA-162909
Infectious disease R-HSA-5663205
Hedgehog 'on' state R-HSA-5632684
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of proteins R-HSA-392499
Hh mutants are degraded by ERAD R-HSA-5362768
Post-translational protein modification R-HSA-597592
KEAP1-NFE2L2 pathway R-HSA-9755511
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hedgehog 'off' state R-HSA-5610787
Axon guidance R-HSA-422475
Innate Immune System R-HSA-168249
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G2/M Checkpoints R-HSA-69481
Transport of small molecules R-HSA-382551
Regulation of RUNX3 expression and activity R-HSA-8941858
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Metabolism of polyamines R-HSA-351202
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Antigen processing-Cross presentation R-HSA-1236975
RAF/MAP kinase cascade R-HSA-5673001
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Assembly of the pre-replicative complex R-HSA-68867
Mitotic G1 phase and G1/S transition R-HSA-453279
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Activation of NF-kappaB in B cells R-HSA-1169091
G1/S DNA Damage Checkpoints R-HSA-69615
Orc1 removal from chromatin R-HSA-68949
Disease R-HSA-1643685
Regulation of mitotic cell cycle R-HSA-453276
Regulation of expression of SLITs and ROBOs R-HSA-9010553
FCERI mediated NF-kB activation R-HSA-2871837
Defective CFTR causes cystic fibrosis R-HSA-5678895
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Degradation of DVL R-HSA-4641258
ABC-family proteins mediated transport R-HSA-382556
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell Cycle Checkpoints R-HSA-69620
Regulation of RAS by GAPs R-HSA-5658442
Cellular response to chemical stress R-HSA-9711123
Cellular responses to stress R-HSA-2262752
Metabolism of RNA R-HSA-8953854
TCF dependent signaling in response to WNT R-HSA-201681
Intracellular signaling by second messengers R-HSA-9006925
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK family signaling cascades R-HSA-5683057
Mitotic Anaphase R-HSA-68882
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX2 R-HSA-8878166
Nuclear events mediated by NFE2L2 R-HSA-9759194
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Metabolism R-HSA-1430728
S Phase R-HSA-69242
Generic Transcription Pathway R-HSA-212436
Ub-specific processing proteases R-HSA-5689880
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Hedgehog ligand biogenesis R-HSA-5358346
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Interleukin-1 signaling R-HSA-9020702
Switching of origins to a post-replicative state R-HSA-69052
Cellular responses to stimuli R-HSA-8953897
Signaling by WNT R-HSA-195721
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Programmed Cell Death R-HSA-5357801
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by Interleukins R-HSA-449147
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Regulation of PTEN stability and activity R-HSA-8948751
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Metaphase and Anaphase R-HSA-2555396
Negative regulation of NOTCH4 signaling R-HSA-9604323
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Degradation of AXIN R-HSA-4641257
Signaling by ROBO receptors R-HSA-376176
Cyclin E associated events during G1/S transition R-HSA-69202
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Transcriptional regulation by RUNX3 R-HSA-8878159
Stabilization of p53 R-HSA-69541
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
MAPK6/MAPK4 signaling R-HSA-5687128
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Beta-catenin independent WNT signaling R-HSA-3858494
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
HIV Infection R-HSA-162906
Signaling by NOTCH R-HSA-157118
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by the B Cell Receptor (BCR) R-HSA-983705
G2/M Transition R-HSA-69275
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Nervous system development R-HSA-9675108
Signaling by Hedgehog R-HSA-5358351
Regulation of Apoptosis R-HSA-169911
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Hh mutants abrogate ligand secretion R-HSA-5387390
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
C-type lectin receptors (CLRs) R-HSA-5621481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
CLEC7A (Dectin-1) signaling R-HSA-5607764
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Mitotic G2-G2/M phases R-HSA-453274
Immune System R-HSA-168256
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of PTEN stability and activity R-HSA-8948751
Apoptosis R-HSA-109581
Transport of small molecules R-HSA-382551
Separation of Sister Chromatids R-HSA-2467813
Degradation of GLI2 by the proteasome R-HSA-5610783
Cyclin E associated events during G1/S transition R-HSA-69202
Cellular response to chemical stress R-HSA-9711123
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cell Cycle Checkpoints R-HSA-69620
ER-Phagosome pathway R-HSA-1236974
G1/S Transition R-HSA-69206
DNA Replication Pre-Initiation R-HSA-69002
Assembly of the pre-replicative complex R-HSA-68867
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Downstream TCR signaling R-HSA-202424
Class I MHC mediated antigen processing & presentation R-HSA-983169
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Regulation of Apoptosis R-HSA-169911
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX3 expression and activity R-HSA-8941858
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
HIV Infection R-HSA-162906
Cytokine Signaling in Immune system R-HSA-1280215
MAPK1/MAPK3 signaling R-HSA-5684996
Degradation of GLI1 by the proteasome R-HSA-5610780
Cellular responses to stimuli R-HSA-8953897
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Signaling by WNT R-HSA-195721
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Interleukin-1 family signaling R-HSA-446652
Axon guidance R-HSA-422475
Switching of origins to a post-replicative state R-HSA-69052
Nervous system development R-HSA-9675108
Negative regulation of NOTCH4 signaling R-HSA-9604323
Degradation of AXIN R-HSA-4641257
Intracellular signaling by second messengers R-HSA-9006925
ABC transporter disorders R-HSA-5619084
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Antigen processing-Cross presentation R-HSA-1236975
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK6/MAPK4 signaling R-HSA-5687128
Degradation of DVL R-HSA-4641258
CLEC7A (Dectin-1) signaling R-HSA-5607764
Transcriptional regulation by RUNX1 R-HSA-8878171
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Immune System R-HSA-168256
Regulation of RUNX2 expression and activity R-HSA-8939902
Ub-specific processing proteases R-HSA-5689880
Mitotic G2-G2/M phases R-HSA-453274
FCERI mediated NF-kB activation R-HSA-2871837
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
C-type lectin receptors (CLRs) R-HSA-5621481
Metabolism of RNA R-HSA-8953854
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Beta-catenin independent WNT signaling R-HSA-3858494
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Nuclear events mediated by NFE2L2 R-HSA-9759194
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Orc1 removal from chromatin R-HSA-68949
Metabolism of proteins R-HSA-392499
UCH proteinases R-HSA-5689603
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Developmental Biology R-HSA-1266738
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle, Mitotic R-HSA-69278
Hedgehog 'off' state R-HSA-5610787
KEAP1-NFE2L2 pathway R-HSA-9755511
p53-Dependent G1 DNA Damage Response R-HSA-69563
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cellular response to hypoxia R-HSA-1234174
Signaling by NOTCH4 R-HSA-9013694
PCP/CE pathway R-HSA-4086400
Regulation of expression of SLITs and ROBOs R-HSA-9010553
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Hedgehog ligand biogenesis R-HSA-5358346
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Regulation of RAS by GAPs R-HSA-5658442
MAPK family signaling cascades R-HSA-5683057
Innate Immune System R-HSA-168249
Deubiquitination R-HSA-5688426
Infectious disease R-HSA-5663205
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neddylation R-HSA-8951664
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Gene expression (Transcription) R-HSA-74160
Interleukin-1 signaling R-HSA-9020702
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Hedgehog 'on' state R-HSA-5632684
Mitotic Anaphase R-HSA-68882
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Hedgehog R-HSA-5358351
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
TCF dependent signaling in response to WNT R-HSA-201681
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TCR signaling R-HSA-202403
Metabolism of polyamines R-HSA-351202
Signaling by ROBO receptors R-HSA-376176
Hh mutants are degraded by ERAD R-HSA-5362768
Signal Transduction R-HSA-162582
Programmed Cell Death R-HSA-5357801
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX2 R-HSA-8878166
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic Metaphase and Anaphase R-HSA-2555396
DNA Replication R-HSA-69306
Disorders of transmembrane transporters R-HSA-5619115
G1/S DNA Damage Checkpoints R-HSA-69615
p53-Independent DNA Damage Response R-HSA-69610
ABC-family proteins mediated transport R-HSA-382556
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Synthesis of DNA R-HSA-69239
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream TCR signaling R-HSA-202424
Assembly of the pre-replicative complex R-HSA-68867
Disease R-HSA-1643685
Hh mutants abrogate ligand secretion R-HSA-5387390
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by NOTCH R-HSA-157118
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
MAPK family signaling cascades R-HSA-5683057
Mitotic G1 phase and G1/S transition R-HSA-453279
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Asymmetric localization of PCP proteins R-HSA-4608870
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Negative regulation of NOTCH4 signaling R-HSA-9604323
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Hedgehog ligand biogenesis R-HSA-5358346
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Host Interactions of HIV factors R-HSA-162909
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-1 signaling R-HSA-9020702
CLEC7A (Dectin-1) signaling R-HSA-5607764
Metabolism R-HSA-1430728
Transcriptional regulation by RUNX2 R-HSA-8878166
RAF/MAP kinase cascade R-HSA-5673001
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disorders of transmembrane transporters R-HSA-5619115
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of RUNX2 expression and activity R-HSA-8939902
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
M Phase R-HSA-68886
G2/M Checkpoints R-HSA-69481
Cellular response to chemical stress R-HSA-9711123
Mitotic Anaphase R-HSA-68882
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by WNT R-HSA-195721
Antigen processing-Cross presentation R-HSA-1236975
Degradation of beta-catenin by the destruction complex R-HSA-195253
Orc1 removal from chromatin R-HSA-68949
Degradation of GLI1 by the proteasome R-HSA-5610780
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by Interleukins R-HSA-449147
Degradation of DVL R-HSA-4641258
Signaling by Hedgehog R-HSA-5358351
Metabolism of RNA R-HSA-8953854
Programmed Cell Death R-HSA-5357801
KEAP1-NFE2L2 pathway R-HSA-9755511
ABC transporter disorders R-HSA-5619084
PTEN Regulation R-HSA-6807070
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cell Cycle, Mitotic R-HSA-69278
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication Pre-Initiation R-HSA-69002
Degradation of AXIN R-HSA-4641257
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 family signaling R-HSA-446652
DNA Replication R-HSA-69306
Switching of origins to a post-replicative state R-HSA-69052
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cell Cycle Checkpoints R-HSA-69620
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of Apoptosis R-HSA-169911
Metabolism of proteins R-HSA-392499
Separation of Sister Chromatids R-HSA-2467813
Regulation of expression of SLITs and ROBOs R-HSA-9010553
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Infectious disease R-HSA-5663205
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic G2-G2/M phases R-HSA-453274
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
Cellular response to hypoxia R-HSA-1234174
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Developmental Biology R-HSA-1266738
HIV Infection R-HSA-162906
Regulation of RAS by GAPs R-HSA-5658442
Vif-mediated degradation of APOBEC3G R-HSA-180585
Hedgehog 'off' state R-HSA-5610787
Defective CFTR causes cystic fibrosis R-HSA-5678895
Nuclear events mediated by NFE2L2 R-HSA-9759194
FCERI mediated NF-kB activation R-HSA-2871837
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
G1/S Transition R-HSA-69206
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Hedgehog 'on' state R-HSA-5632684
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
TCF dependent signaling in response to WNT R-HSA-201681
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Metabolism of polyamines R-HSA-351202
TCR signaling R-HSA-202403
PCP/CE pathway R-HSA-4086400
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Intracellular signaling by second messengers R-HSA-9006925
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G2/M Transition R-HSA-69275
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
Signaling by ROBO receptors R-HSA-376176
RNA Polymerase II Transcription R-HSA-73857
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
S Phase R-HSA-69242
Hh mutants are degraded by ERAD R-HSA-5362768
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Beta-catenin independent WNT signaling R-HSA-3858494
Mitotic Metaphase and Anaphase R-HSA-2555396
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Dependent G1 DNA Damage Response R-HSA-69563
ER-Phagosome pathway R-HSA-1236974
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Post-translational protein modification R-HSA-597592
Regulation of mitotic cell cycle R-HSA-453276
Stabilization of p53 R-HSA-69541
Cellular responses to stress R-HSA-2262752
UCH proteinases R-HSA-5689603
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX3 R-HSA-8878159
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular responses to stimuli R-HSA-8953897
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Adaptive Immune System R-HSA-1280218
Regulation of mitotic cell cycle R-HSA-453276
Separation of Sister Chromatids R-HSA-2467813
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle Checkpoints R-HSA-69620
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Mitotic Metaphase and Anaphase R-HSA-2555396
Ub-specific processing proteases R-HSA-5689880
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stimuli R-HSA-8953897
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Negative regulation of NOTCH4 signaling R-HSA-9604323
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
M Phase R-HSA-68886
HIV Infection R-HSA-162906
Class I MHC mediated antigen processing & presentation R-HSA-983169
Disorders of transmembrane transporters R-HSA-5619115
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Axon guidance R-HSA-422475
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
Programmed Cell Death R-HSA-5357801
Signaling by WNT R-HSA-195721
PTEN Regulation R-HSA-6807070
Hh mutants are degraded by ERAD R-HSA-5362768
UCH proteinases R-HSA-5689603
Hedgehog 'on' state R-HSA-5632684
Synthesis of DNA R-HSA-69239
Nervous system development R-HSA-9675108
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
ABC-family proteins mediated transport R-HSA-382556
Mitotic G2-G2/M phases R-HSA-453274
Host Interactions of HIV factors R-HSA-162909
Metabolism of amino acids and derivatives R-HSA-71291
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Deubiquitination R-HSA-5688426
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of RAS by GAPs R-HSA-5658442
p53-Independent DNA Damage Response R-HSA-69610
Metabolism of RNA R-HSA-8953854
ABC transporter disorders R-HSA-5619084
Cellular response to chemical stress R-HSA-9711123
Immune System R-HSA-168256
PCP/CE pathway R-HSA-4086400
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
G2/M Transition R-HSA-69275
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cell Cycle, Mitotic R-HSA-69278
Assembly of the pre-replicative complex R-HSA-68867
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of polyamines R-HSA-351202
G2/M Checkpoints R-HSA-69481
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Intracellular signaling by second messengers R-HSA-9006925
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Mitotic Anaphase R-HSA-68882
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to hypoxia R-HSA-1234174
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
RNA Polymerase II Transcription R-HSA-73857
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TCF dependent signaling in response to WNT R-HSA-201681
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Signaling by NOTCH R-HSA-157118
Innate Immune System R-HSA-168249
Vpu mediated degradation of CD4 R-HSA-180534
Regulation of Apoptosis R-HSA-169911
MAPK1/MAPK3 signaling R-HSA-5684996
Regulation of RUNX3 expression and activity R-HSA-8941858
Beta-catenin independent WNT signaling R-HSA-3858494
Degradation of AXIN R-HSA-4641257
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Degradation of DVL R-HSA-4641258
Regulation of RUNX2 expression and activity R-HSA-8939902
Interleukin-1 signaling R-HSA-9020702
Apoptosis R-HSA-109581
DNA Replication Pre-Initiation R-HSA-69002
Cellular responses to stress R-HSA-2262752
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Interleukin-1 family signaling R-HSA-446652
G1/S DNA Damage Checkpoints R-HSA-69615
TCR signaling R-HSA-202403
Stabilization of p53 R-HSA-69541
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Post-translational protein modification R-HSA-597592
p53-Dependent G1 DNA Damage Response R-HSA-69563
Degradation of GLI2 by the proteasome R-HSA-5610783
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle R-HSA-1640170
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cyclin E associated events during G1/S transition R-HSA-69202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Defective CFTR causes cystic fibrosis R-HSA-5678895
Signaling by NOTCH4 R-HSA-9013694
Switching of origins to a post-replicative state R-HSA-69052
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Activation of NF-kappaB in B cells R-HSA-1169091
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Vif-mediated degradation of APOBEC3G R-HSA-180585
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
PIP3 activates AKT signaling R-HSA-1257604
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
G1/S Transition R-HSA-69206
Metabolism of proteins R-HSA-392499
ER-Phagosome pathway R-HSA-1236974
FCERI mediated NF-kB activation R-HSA-2871837
Mitotic G1 phase and G1/S transition R-HSA-453279
Downstream TCR signaling R-HSA-202424
Disease R-HSA-1643685
DNA Replication R-HSA-69306
Neddylation R-HSA-8951664
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Nuclear events mediated by NFE2L2 R-HSA-9759194
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Signaling by Hedgehog R-HSA-5358351
Degradation of GLI1 by the proteasome R-HSA-5610780
Transcriptional regulation by RUNX1 R-HSA-8878171
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Transcriptional regulation by RUNX2 R-HSA-8878166
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK6/MAPK4 signaling R-HSA-5687128
KEAP1-NFE2L2 pathway R-HSA-9755511
Gene expression (Transcription) R-HSA-74160
Hedgehog 'off' state R-HSA-5610787
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Regulation of expression of SLITs and ROBOs R-HSA-9010553
HIV Infection R-HSA-162906
Intracellular signaling by second messengers R-HSA-9006925
Regulation of RAS by GAPs R-HSA-5658442
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX1 R-HSA-8878171
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Degradation of GLI1 by the proteasome R-HSA-5610780
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
Disorders of transmembrane transporters R-HSA-5619115
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
Activation of NF-kappaB in B cells R-HSA-1169091
Switching of origins to a post-replicative state R-HSA-69052
Transcriptional regulation by RUNX2 R-HSA-8878166
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Downstream TCR signaling R-HSA-202424
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
CLEC7A (Dectin-1) signaling R-HSA-5607764
Generic Transcription Pathway R-HSA-212436
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by NOTCH R-HSA-157118
Host Interactions of HIV factors R-HSA-162909
Apoptosis R-HSA-109581
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Cell Cycle R-HSA-1640170
Regulation of PTEN stability and activity R-HSA-8948751
Vpu mediated degradation of CD4 R-HSA-180534
Synthesis of DNA R-HSA-69239
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Metabolism of RNA R-HSA-8953854
Hedgehog 'off' state R-HSA-5610787
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Deubiquitination R-HSA-5688426
Separation of Sister Chromatids R-HSA-2467813
Nuclear events mediated by NFE2L2 R-HSA-9759194
PIP3 activates AKT signaling R-HSA-1257604
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cyclin E associated events during G1/S transition R-HSA-69202
RNA Polymerase II Transcription R-HSA-73857
p53-Independent DNA Damage Response R-HSA-69610
Developmental Biology R-HSA-1266738
Cell Cycle, Mitotic R-HSA-69278
Hedgehog ligand biogenesis R-HSA-5358346
DNA Replication R-HSA-69306
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
Hedgehog 'on' state R-HSA-5632684
Cellular responses to stimuli R-HSA-8953897
Signaling by ROBO receptors R-HSA-376176
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Assembly of the pre-replicative complex R-HSA-68867
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Antigen processing-Cross presentation R-HSA-1236975
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Immune System R-HSA-168256
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Mitotic Anaphase R-HSA-68882
Interleukin-1 signaling R-HSA-9020702
Degradation of AXIN R-HSA-4641257
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Post-translational protein modification R-HSA-597592
S Phase R-HSA-69242
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Nervous system development R-HSA-9675108
G2/M Checkpoints R-HSA-69481
Class I MHC mediated antigen processing & presentation R-HSA-983169
Asymmetric localization of PCP proteins R-HSA-4608870
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cellular responses to stress R-HSA-2262752
Signal Transduction R-HSA-162582
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
G1/S DNA Damage Checkpoints R-HSA-69615
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Degradation of DVL R-HSA-4641258
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism R-HSA-1430728
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of GLI2 by the proteasome R-HSA-5610783
M Phase R-HSA-68886
Regulation of RUNX2 expression and activity R-HSA-8939902
Transcriptional regulation by RUNX3 R-HSA-8878159
G1/S Transition R-HSA-69206
ABC transporter disorders R-HSA-5619084
Metabolism of amino acids and derivatives R-HSA-71291
Ub-specific processing proteases R-HSA-5689880
p53-Dependent G1 DNA Damage Response R-HSA-69563
C-type lectin receptors (CLRs) R-HSA-5621481
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RAF/MAP kinase cascade R-HSA-5673001
Signaling by NOTCH4 R-HSA-9013694
Beta-catenin independent WNT signaling R-HSA-3858494
KEAP1-NFE2L2 pathway R-HSA-9755511
Signaling by WNT R-HSA-195721
FCERI mediated NF-kB activation R-HSA-2871837
Axon guidance R-HSA-422475
TCF dependent signaling in response to WNT R-HSA-201681
MAPK1/MAPK3 signaling R-HSA-5684996
DNA Replication Pre-Initiation R-HSA-69002
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
ABC-family proteins mediated transport R-HSA-382556
Vif-mediated degradation of APOBEC3G R-HSA-180585
Neddylation R-HSA-8951664
TCR signaling R-HSA-202403
Interleukin-1 family signaling R-HSA-446652
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Cellular response to chemical stress R-HSA-9711123
Signaling by Hedgehog R-HSA-5358351
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
MAPK6/MAPK4 signaling R-HSA-5687128
MAPK family signaling cascades R-HSA-5683057
Stabilization of p53 R-HSA-69541
Negative regulation of NOTCH4 signaling R-HSA-9604323
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of Apoptosis R-HSA-169911
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Mitotic G2-G2/M phases R-HSA-453274
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
PCP/CE pathway R-HSA-4086400
Metabolism of polyamines R-HSA-351202
Hh mutants abrogate ligand secretion R-HSA-5387390
Defective CFTR causes cystic fibrosis R-HSA-5678895
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Disease R-HSA-1643685
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
Disorders of transmembrane transporters R-HSA-5619115
RNA Polymerase II Transcription R-HSA-73857
M Phase R-HSA-68886
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX2 R-HSA-8878166
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
TCR signaling R-HSA-202403
Degradation of beta-catenin by the destruction complex R-HSA-195253
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Hh mutants are degraded by ERAD R-HSA-5362768
Host Interactions of HIV factors R-HSA-162909
Metabolism of RNA R-HSA-8953854
Metabolism of proteins R-HSA-392499
Hedgehog ligand biogenesis R-HSA-5358346
Metabolism R-HSA-1430728
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Signaling by NOTCH4 R-HSA-9013694
G2/M Checkpoints R-HSA-69481
Mitotic Metaphase and Anaphase R-HSA-2555396
C-type lectin receptors (CLRs) R-HSA-5621481
CLEC7A (Dectin-1) signaling R-HSA-5607764
Cellular response to hypoxia R-HSA-1234174
ABC-family proteins mediated transport R-HSA-382556
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
ABC transporter disorders R-HSA-5619084
DNA Replication Pre-Initiation R-HSA-69002
Downstream TCR signaling R-HSA-202424
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
Cellular response to chemical stress R-HSA-9711123
Beta-catenin independent WNT signaling R-HSA-3858494
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
Regulation of PTEN stability and activity R-HSA-8948751
DNA Replication R-HSA-69306
Cellular responses to stimuli R-HSA-8953897
G1/S DNA Damage Checkpoints R-HSA-69615
ER-Phagosome pathway R-HSA-1236974
Signaling by Hedgehog R-HSA-5358351
Infectious disease R-HSA-5663205
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Nervous system development R-HSA-9675108
Cell Cycle R-HSA-1640170
Regulation of RUNX2 expression and activity R-HSA-8939902
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Orc1 removal from chromatin R-HSA-68949
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Adaptive Immune System R-HSA-1280218
Neddylation R-HSA-8951664
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signal Transduction R-HSA-162582
Vpu mediated degradation of CD4 R-HSA-180534
UCH proteinases R-HSA-5689603
Hh mutants abrogate ligand secretion R-HSA-5387390
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Regulation of RAS by GAPs R-HSA-5658442
Degradation of GLI1 by the proteasome R-HSA-5610780
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Degradation of AXIN R-HSA-4641257
p53-Independent DNA Damage Response R-HSA-69610
Interleukin-1 family signaling R-HSA-446652
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Hedgehog 'off' state R-HSA-5610787
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCF dependent signaling in response to WNT R-HSA-201681
Axon guidance R-HSA-422475
Synthesis of DNA R-HSA-69239
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Signaling by NOTCH R-HSA-157118
Gene expression (Transcription) R-HSA-74160
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ROBO receptors R-HSA-376176
Switching of origins to a post-replicative state R-HSA-69052
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Degradation of GLI2 by the proteasome R-HSA-5610783
Nuclear events mediated by NFE2L2 R-HSA-9759194
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
PCP/CE pathway R-HSA-4086400
Defective CFTR causes cystic fibrosis R-HSA-5678895
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
G2/M Transition R-HSA-69275
Metabolism of amino acids and derivatives R-HSA-71291
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Immune System R-HSA-168256
Transport of small molecules R-HSA-382551
HIV Infection R-HSA-162906
Generic Transcription Pathway R-HSA-212436
PTEN Regulation R-HSA-6807070
Transcriptional regulation by RUNX3 R-HSA-8878159
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX1 R-HSA-8878171
Stabilization of p53 R-HSA-69541
Developmental Biology R-HSA-1266738
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of Apoptosis R-HSA-169911
Assembly of the pre-replicative complex R-HSA-68867
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of mitotic cell cycle R-HSA-453276
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Negative regulation of NOTCH4 signaling R-HSA-9604323
FCERI mediated NF-kB activation R-HSA-2871837
KEAP1-NFE2L2 pathway R-HSA-9755511
Separation of Sister Chromatids R-HSA-2467813
G1/S Transition R-HSA-69206
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Activation of NF-kappaB in B cells R-HSA-1169091
MAPK6/MAPK4 signaling R-HSA-5687128
Vif-mediated degradation of APOBEC3G R-HSA-180585
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Asymmetric localization of PCP proteins R-HSA-4608870
Degradation of DVL R-HSA-4641258
S Phase R-HSA-69242
Interleukin-1 signaling R-HSA-9020702
RAF/MAP kinase cascade R-HSA-5673001
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Deubiquitination R-HSA-5688426
Metabolism of polyamines R-HSA-351202
Mitotic G2-G2/M phases R-HSA-453274
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114

Expression Atlas ENSG00000129084
NCBI gene (formerly Entrezgene) 5682
GeneCards 9530
HGNC Symbol HGNC:9530
MIM gene 602854
UniProtKB Gene Name P25786
WikiGene 5682
Gene: XDH
Ensembl ID : ENSG00000158125
Description: xanthine dehydrogenase
Gene Synonyms: XO,XOR
6 APIs:
210 Possible Orthologues:

Nucleotide catabolism R-HSA-8956319
Butyrophilin (BTN) family interactions R-HSA-8851680
Azathioprine ADME R-HSA-9748787
Metabolism of nucleotides R-HSA-15869
Drug ADME R-HSA-9748784
Immune System R-HSA-168256
Metabolism R-HSA-1430728
Adaptive Immune System R-HSA-1280218
Purine catabolism R-HSA-74259
Azathioprine ADME R-HSA-9748787
Adaptive Immune System R-HSA-1280218
Nucleotide catabolism R-HSA-8956319
Immune System R-HSA-168256
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Butyrophilin (BTN) family interactions R-HSA-8851680
Drug ADME R-HSA-9748784
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Drug ADME R-HSA-9748784
Butyrophilin (BTN) family interactions R-HSA-8851680
Immune System R-HSA-168256
Purine catabolism R-HSA-74259
Metabolism of nucleotides R-HSA-15869
Adaptive Immune System R-HSA-1280218
Azathioprine ADME R-HSA-9748787
Nucleotide catabolism R-HSA-8956319
Adaptive Immune System R-HSA-1280218
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Drug ADME R-HSA-9748784
Purine catabolism R-HSA-74259
Butyrophilin (BTN) family interactions R-HSA-8851680
Azathioprine ADME R-HSA-9748787
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Azathioprine ADME R-HSA-9748787
Purine catabolism R-HSA-74259
Butyrophilin (BTN) family interactions R-HSA-8851680
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Drug ADME R-HSA-9748784
Adaptive Immune System R-HSA-1280218
Azathioprine ADME R-HSA-9748787
Butyrophilin (BTN) family interactions R-HSA-8851680
Immune System R-HSA-168256
Metabolism of nucleotides R-HSA-15869
Drug ADME R-HSA-9748784
Nucleotide catabolism R-HSA-8956319
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Immune System R-HSA-168256
Nucleotide catabolism R-HSA-8956319
Adaptive Immune System R-HSA-1280218
Purine catabolism R-HSA-74259
Drug ADME R-HSA-9748784
Metabolism R-HSA-1430728
Azathioprine ADME R-HSA-9748787
Butyrophilin (BTN) family interactions R-HSA-8851680
Immune System R-HSA-168256
Azathioprine ADME R-HSA-9748787
Butyrophilin (BTN) family interactions R-HSA-8851680
Drug ADME R-HSA-9748784
Adaptive Immune System R-HSA-1280218
Nucleotide catabolism R-HSA-8956319
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Butyrophilin (BTN) family interactions R-HSA-8851680
Metabolism of nucleotides R-HSA-15869
Adaptive Immune System R-HSA-1280218
Drug ADME R-HSA-9748784
Nucleotide catabolism R-HSA-8956319
Immune System R-HSA-168256
Azathioprine ADME R-HSA-9748787
Purine catabolism R-HSA-74259
Purine catabolism R-HSA-74259
Adaptive Immune System R-HSA-1280218
Drug ADME R-HSA-9748784
Butyrophilin (BTN) family interactions R-HSA-8851680
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Azathioprine ADME R-HSA-9748787
Metabolism R-HSA-1430728
Immune System R-HSA-168256
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Drug ADME R-HSA-9748784
Azathioprine ADME R-HSA-9748787
Adaptive Immune System R-HSA-1280218
Butyrophilin (BTN) family interactions R-HSA-8851680
Purine catabolism R-HSA-74259

Expression Atlas ENSG00000158125
NCBI gene (formerly Entrezgene) 7498
GeneCards 12805
HGNC Symbol HGNC:12805
MIM gene 607633
MIM morbid 278300
UniProtKB Gene Name P47989
WikiGene 7498