Gene: ENPP2
Ensembl ID : ENSG00000136960
Description: ectonucleotide pyrophosphatase/phosphodiesterase 2
Gene Synonyms: ATX,PD-IALPHA,PDNP2
1 APIs:
227 Possible Orthologues:

Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Vitamin B5 (pantothenate) metabolism R-HSA-199220
Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism R-HSA-1430728
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Vitamin B5 (pantothenate) metabolism R-HSA-199220

Expression Atlas ENSG00000136960
NCBI gene (formerly Entrezgene) 5168
GeneCards 3357
HGNC Symbol HGNC:3357
MIM gene 601060
UniProtKB Gene Name Q13822
WikiGene 5168
Gene: MAPK11
Ensembl ID : ENSG00000185386
Description: mitogen-activated protein kinase 11
Gene Synonyms: P38-2,P38BETA,PRKM11,SAPK2
3 APIs:
201 Possible Orthologues:

Signaling by VEGF R-HSA-194138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Axon guidance R-HSA-422475
VEGFA-VEGFR2 Pathway R-HSA-4420097
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Generic Transcription Pathway R-HSA-212436
Signalling to ERKs R-HSA-187687
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPase Effectors R-HSA-195258
Netrin-1 signaling R-HSA-373752
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Metabolism of RNA R-HSA-8953854
Myogenesis R-HSA-525793
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
p38MAPK events R-HSA-171007
Mitochondrial biogenesis R-HSA-1592230
DSCAM interactions R-HSA-376172
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cellular responses to stress R-HSA-2262752
ERK/MAPK targets R-HSA-198753
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NOD1/2 Signaling Pathway R-HSA-168638
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Toll-like Receptor Cascades R-HSA-168898
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signalling to RAS R-HSA-167044
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Activation of the AP-1 family of transcription factors R-HSA-450341
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Organelle biogenesis and maintenance R-HSA-1852241
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Nervous system development R-HSA-9675108
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Signaling by NTRK1 (TRKA) R-HSA-187037
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Developmental Biology R-HSA-1266738
Interleukin-17 signaling R-HSA-448424
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Cellular Senescence R-HSA-2559583
p38MAPK events R-HSA-171007
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
ERK/MAPK targets R-HSA-198753
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Mitochondrial biogenesis R-HSA-1592230
DSCAM interactions R-HSA-376172
Regulation of TP53 Activity R-HSA-5633007
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll-like Receptor Cascades R-HSA-168898
Signal Transduction R-HSA-162582
Activation of the AP-1 family of transcription factors R-HSA-450341
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
RNA Polymerase II Transcription R-HSA-73857
NOD1/2 Signaling Pathway R-HSA-168638
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRKs R-HSA-166520
Organelle biogenesis and maintenance R-HSA-1852241
VEGFA-VEGFR2 Pathway R-HSA-4420097
Netrin-1 signaling R-HSA-373752
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional Regulation by TP53 R-HSA-3700989
MyD88-independent TLR4 cascade R-HSA-166166
Signalling to ERKs R-HSA-187687
Signalling to RAS R-HSA-167044
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Generic Transcription Pathway R-HSA-212436
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Axon guidance R-HSA-422475
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Myogenesis R-HSA-525793
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
Nervous system development R-HSA-9675108
Signaling by Interleukins R-HSA-449147
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Metabolism of RNA R-HSA-8953854
RHO GTPase Effectors R-HSA-195258
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by VEGF R-HSA-194138
Innate Immune System R-HSA-168249
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Cellular responses to stress R-HSA-2262752
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Axon guidance R-HSA-422475
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MAP kinase activation R-HSA-450294
Signalling to RAS R-HSA-167044
Signalling to ERKs R-HSA-187687
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Metabolism of RNA R-HSA-8953854
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by Rho GTPases R-HSA-194315
Toll-like Receptor Cascades R-HSA-168898
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by NTRKs R-HSA-166520
DSCAM interactions R-HSA-376172
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 dependent cascade initiated on endosome R-HSA-975155
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nervous system development R-HSA-9675108
RHO GTPase Effectors R-HSA-195258
VEGFA-VEGFR2 Pathway R-HSA-4420097
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NOD1/2 Signaling Pathway R-HSA-168638
Transcriptional Regulation by TP53 R-HSA-3700989
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Gene expression (Transcription) R-HSA-74160
Netrin-1 signaling R-HSA-373752
Myogenesis R-HSA-525793
ERK/MAPK targets R-HSA-198753
Cellular responses to stimuli R-HSA-8953897
Cellular Senescence R-HSA-2559583
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by VEGF R-HSA-194138
Mitochondrial biogenesis R-HSA-1592230
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
p38MAPK events R-HSA-171007
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signaling by NTRK1 (TRKA) R-HSA-187037
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Interleukin-17 signaling R-HSA-448424
RNA Polymerase II Transcription R-HSA-73857
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
MyD88 cascade initiated on plasma membrane R-HSA-975871
Organelle biogenesis and maintenance R-HSA-1852241
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Myogenesis R-HSA-525793
Interleukin-17 signaling R-HSA-448424
MAP kinase activation R-HSA-450294
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stimuli R-HSA-8953897
Signaling by NTRKs R-HSA-166520
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
Generic Transcription Pathway R-HSA-212436
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cellular Senescence R-HSA-2559583
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to ERKs R-HSA-187687
NOD1/2 Signaling Pathway R-HSA-168638
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cellular responses to stress R-HSA-2262752
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
MyD88-independent TLR4 cascade R-HSA-166166
Signaling by VEGF R-HSA-194138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
RHO GTPase Effectors R-HSA-195258
p38MAPK events R-HSA-171007
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
DSCAM interactions R-HSA-376172
Metabolism of RNA R-HSA-8953854
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signalling to RAS R-HSA-167044
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Organelle biogenesis and maintenance R-HSA-1852241
Mitochondrial biogenesis R-HSA-1592230
Innate Immune System R-HSA-168249
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Rho GTPases R-HSA-194315
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Netrin-1 signaling R-HSA-373752
Developmental Biology R-HSA-1266738
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
VEGFA-VEGFR2 Pathway R-HSA-4420097
Nervous system development R-HSA-9675108
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll-like Receptor Cascades R-HSA-168898
Signaling by Interleukins R-HSA-449147
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
Organelle biogenesis and maintenance R-HSA-1852241
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Myogenesis R-HSA-525793
RNA Polymerase II Transcription R-HSA-73857
Cellular Senescence R-HSA-2559583
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DSCAM interactions R-HSA-376172
Cellular responses to stress R-HSA-2262752
Activation of the AP-1 family of transcription factors R-HSA-450341
Developmental Biology R-HSA-1266738
Netrin-1 signaling R-HSA-373752
RHO GTPase Effectors R-HSA-195258
Transcriptional Regulation by TP53 R-HSA-3700989
p38MAPK events R-HSA-171007
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by VEGF R-HSA-194138
Metabolism of RNA R-HSA-8953854
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Gene expression (Transcription) R-HSA-74160
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NOD1/2 Signaling Pathway R-HSA-168638
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signalling to RAS R-HSA-167044
Signaling by Interleukins R-HSA-449147
Signaling by Rho GTPases R-HSA-194315
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitochondrial biogenesis R-HSA-1592230
Cellular responses to stimuli R-HSA-8953897
VEGFA-VEGFR2 Pathway R-HSA-4420097
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRK1 (TRKA) R-HSA-187037
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signal Transduction R-HSA-162582
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Nervous system development R-HSA-9675108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Interleukin-17 signaling R-HSA-448424
Axon guidance R-HSA-422475
Cytokine Signaling in Immune system R-HSA-1280215
ERK/MAPK targets R-HSA-198753
Toll-like Receptor Cascades R-HSA-168898
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by Rho GTPases R-HSA-194315
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Generic Transcription Pathway R-HSA-212436
Oxidative Stress Induced Senescence R-HSA-2559580
Signaling by NTRKs R-HSA-166520
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
Immune System R-HSA-168256
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism of RNA R-HSA-8953854
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Interleukins R-HSA-449147
Organelle biogenesis and maintenance R-HSA-1852241
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll-like Receptor Cascades R-HSA-168898
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 dependent cascade initiated on endosome R-HSA-975155
RHO GTPase Effectors R-HSA-195258
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
ERK/MAPK targets R-HSA-198753
Signaling by VEGF R-HSA-194138
Activation of the AP-1 family of transcription factors R-HSA-450341
Cellular Senescence R-HSA-2559583
NOD1/2 Signaling Pathway R-HSA-168638
Myogenesis R-HSA-525793
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signalling to RAS R-HSA-167044
Signalling to ERKs R-HSA-187687
Interleukin-17 signaling R-HSA-448424
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Developmental Biology R-HSA-1266738
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signal Transduction R-HSA-162582
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity R-HSA-5633007
p38MAPK events R-HSA-171007
Signaling by NTRK1 (TRKA) R-HSA-187037
Netrin-1 signaling R-HSA-373752
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DSCAM interactions R-HSA-376172
MAP kinase activation R-HSA-450294
Mitochondrial biogenesis R-HSA-1592230
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Gene expression (Transcription) R-HSA-74160
Cellular responses to stress R-HSA-2262752
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
RHO GTPase Effectors R-HSA-195258
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Toll-like Receptor Cascades R-HSA-168898
MyD88-independent TLR4 cascade R-HSA-166166
Signal Transduction R-HSA-162582
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Signaling by Interleukins R-HSA-449147
ERK/MAPK targets R-HSA-198753
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
DSCAM interactions R-HSA-376172
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by VEGF R-HSA-194138
Nervous system development R-HSA-9675108
Signalling to ERKs R-HSA-187687
Interleukin-17 signaling R-HSA-448424
Signaling by NTRKs R-HSA-166520
Cellular Senescence R-HSA-2559583
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAP kinase activation R-HSA-450294
Innate Immune System R-HSA-168249
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
VEGFA-VEGFR2 Pathway R-HSA-4420097
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity R-HSA-5633007
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
Metabolism of RNA R-HSA-8953854
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Signalling to RAS R-HSA-167044
Organelle biogenesis and maintenance R-HSA-1852241
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of the AP-1 family of transcription factors R-HSA-450341
Immune System R-HSA-168256
p38MAPK events R-HSA-171007
Oxidative Stress Induced Senescence R-HSA-2559580
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Developmental Biology R-HSA-1266738
Netrin-1 signaling R-HSA-373752
Mitochondrial biogenesis R-HSA-1592230
Myogenesis R-HSA-525793
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Cellular responses to stress R-HSA-2262752
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Axon guidance R-HSA-422475
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPase Effectors R-HSA-195258
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Signaling by NTRK1 (TRKA) R-HSA-187037
Regulation of TP53 Activity R-HSA-5633007
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
NOD1/2 Signaling Pathway R-HSA-168638
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Signaling by Rho GTPases R-HSA-194315
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by VEGF R-HSA-194138
Netrin-1 signaling R-HSA-373752
Transcriptional Regulation by TP53 R-HSA-3700989
MAP kinase activation R-HSA-450294
Signaling by NTRKs R-HSA-166520
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
activated TAK1 mediates p38 MAPK activation R-HSA-450302
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signalling to RAS R-HSA-167044
Cytokine Signaling in Immune system R-HSA-1280215
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Activation of the AP-1 family of transcription factors R-HSA-450341
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
p38MAPK events R-HSA-171007
Axon guidance R-HSA-422475
DSCAM interactions R-HSA-376172
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Metabolism of RNA R-HSA-8953854
Generic Transcription Pathway R-HSA-212436
Mitochondrial biogenesis R-HSA-1592230
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signalling to ERKs R-HSA-187687
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
ERK/MAPK targets R-HSA-198753
Myogenesis R-HSA-525793
RNA Polymerase II Transcription R-HSA-73857
MyD88-independent TLR4 cascade R-HSA-166166
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Cellular Senescence R-HSA-2559583
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Organelle biogenesis and maintenance R-HSA-1852241
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
p38MAPK events R-HSA-171007
Metabolism of RNA R-HSA-8953854
Organelle biogenesis and maintenance R-HSA-1852241
activated TAK1 mediates p38 MAPK activation R-HSA-450302
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NOD1/2 Signaling Pathway R-HSA-168638
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signalling to RAS R-HSA-167044
Cellular responses to stress R-HSA-2262752
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by NTRK1 (TRKA) R-HSA-187037
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Signalling to ERKs R-HSA-187687
Developmental Biology R-HSA-1266738
Activation of the AP-1 family of transcription factors R-HSA-450341
Toll-like Receptor Cascades R-HSA-168898
Cellular Senescence R-HSA-2559583
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
DSCAM interactions R-HSA-376172
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Axon guidance R-HSA-422475
Signaling by VEGF R-HSA-194138
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Nervous system development R-HSA-9675108
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MAP kinase activation R-HSA-450294
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Immune System R-HSA-168256
RHO GTPase Effectors R-HSA-195258
RNA Polymerase II Transcription R-HSA-73857
Myogenesis R-HSA-525793
Mitochondrial biogenesis R-HSA-1592230
Interleukin-17 signaling R-HSA-448424
Cellular responses to stimuli R-HSA-8953897
Signaling by NTRKs R-HSA-166520
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
ERK/MAPK targets R-HSA-198753
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Netrin-1 signaling R-HSA-373752
MyD88 cascade initiated on plasma membrane R-HSA-975871
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Regulation of TP53 Activity R-HSA-5633007
Innate Immune System R-HSA-168249
Mitochondrial biogenesis R-HSA-1592230
Axon guidance R-HSA-422475
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular Senescence R-HSA-2559583
Interleukin-17 signaling R-HSA-448424
ERK/MAPK targets R-HSA-198753
Signaling by NTRKs R-HSA-166520
Immune System R-HSA-168256
MyD88-independent TLR4 cascade R-HSA-166166
RHO GTPases Activate NADPH Oxidases R-HSA-5668599
Transcriptional Regulation by TP53 R-HSA-3700989
Organelle biogenesis and maintenance R-HSA-1852241
Signalling to RAS R-HSA-167044
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DSCAM interactions R-HSA-376172
Signaling by VEGF R-HSA-194138
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll-like Receptor Cascades R-HSA-168898
Netrin-1 signaling R-HSA-373752
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604
Activation of the AP-1 family of transcription factors R-HSA-450341
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Metabolism of RNA R-HSA-8953854
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK1 (TRKA) R-HSA-187037
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of TP53 Activity R-HSA-5633007
Developmental Biology R-HSA-1266738
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Innate Immune System R-HSA-168249
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nervous system development R-HSA-9675108
MAP kinase activation R-HSA-450294
Signalling to ERKs R-HSA-187687
Myogenesis R-HSA-525793
VEGFA-VEGFR2 Pathway R-HSA-4420097
Oxidative Stress Induced Senescence R-HSA-2559580
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
p38MAPK events R-HSA-171007
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular responses to stress R-HSA-2262752
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282
Signaling by Rho GTPases R-HSA-194315
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
activated TAK1 mediates p38 MAPK activation R-HSA-450302
RHO GTPase Effectors R-HSA-195258
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164

Expression Atlas ENSG00000185386
NCBI gene (formerly Entrezgene) 5600
GeneCards 6873
HGNC Symbol HGNC:6873
MIM gene 602898
UniProtKB Gene Name Q15759
WikiGene 5600
Gene: PARP2
Ensembl ID : ENSG00000129484
Description: poly(ADP-ribose) polymerase 2
Gene Synonyms: ADPRTL2,ARTD2
10 APIs:
186 Possible Orthologues:

DNA Repair R-HSA-73894
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Formation of Incision Complex in GG-NER R-HSA-5696395
Dual Incision in GG-NER R-HSA-5696400
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Resolution of Abasic Sites (AP sites) R-HSA-73933
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
DNA Damage Recognition in GG-NER R-HSA-5696394
Homology Directed Repair R-HSA-5693538
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Base Excision Repair R-HSA-73884
DNA Double-Strand Break Repair R-HSA-5693532
Nucleotide Excision Repair R-HSA-5696398
Nucleotide Excision Repair R-HSA-5696398
Formation of Incision Complex in GG-NER R-HSA-5696395
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Homology Directed Repair R-HSA-5693538
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
DNA Damage Recognition in GG-NER R-HSA-5696394
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Double-Strand Break Repair R-HSA-5693532
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Dual Incision in GG-NER R-HSA-5696400
DNA Repair R-HSA-73894
Base Excision Repair R-HSA-73884
DNA Damage Recognition in GG-NER R-HSA-5696394
Nucleotide Excision Repair R-HSA-5696398
Resolution of Abasic Sites (AP sites) R-HSA-73933
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Formation of Incision Complex in GG-NER R-HSA-5696395
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
DNA Double-Strand Break Repair R-HSA-5693532
Dual Incision in GG-NER R-HSA-5696400
Homology Directed Repair R-HSA-5693538
Base Excision Repair R-HSA-73884
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Repair R-HSA-73894
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Dual Incision in GG-NER R-HSA-5696400
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Formation of Incision Complex in GG-NER R-HSA-5696395
Homology Directed Repair R-HSA-5693538
Resolution of Abasic Sites (AP sites) R-HSA-73933
Base Excision Repair R-HSA-73884
DNA Damage Recognition in GG-NER R-HSA-5696394
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Nucleotide Excision Repair R-HSA-5696398
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Repair R-HSA-73894
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Damage Recognition in GG-NER R-HSA-5696394
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Formation of Incision Complex in GG-NER R-HSA-5696395
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Dual Incision in GG-NER R-HSA-5696400
Nucleotide Excision Repair R-HSA-5696398
Base Excision Repair R-HSA-73884
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Homology Directed Repair R-HSA-5693538
DNA Double-Strand Break Repair R-HSA-5693532
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Damage Recognition in GG-NER R-HSA-5696394
DNA Double-Strand Break Repair R-HSA-5693532
Homology Directed Repair R-HSA-5693538
Nucleotide Excision Repair R-HSA-5696398
Dual Incision in GG-NER R-HSA-5696400
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Base Excision Repair R-HSA-73884
Formation of Incision Complex in GG-NER R-HSA-5696395
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
DNA Repair R-HSA-73894
Base Excision Repair R-HSA-73884
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Formation of Incision Complex in GG-NER R-HSA-5696395
DNA Damage Recognition in GG-NER R-HSA-5696394
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Homology Directed Repair R-HSA-5693538
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Resolution of Abasic Sites (AP sites) R-HSA-73933
Dual Incision in GG-NER R-HSA-5696400
DNA Repair R-HSA-73894
Nucleotide Excision Repair R-HSA-5696398
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Resolution of Abasic Sites (AP sites) R-HSA-73933
DNA Damage Recognition in GG-NER R-HSA-5696394
Dual Incision in GG-NER R-HSA-5696400
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Base Excision Repair R-HSA-73884
Formation of Incision Complex in GG-NER R-HSA-5696395
DNA Double-Strand Break Repair R-HSA-5693532
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
Homology Directed Repair R-HSA-5693538
Nucleotide Excision Repair R-HSA-5696398
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
DNA Double-Strand Break Repair R-HSA-5693532
Base Excision Repair R-HSA-73884
Homology Directed Repair R-HSA-5693538
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
Nucleotide Excision Repair R-HSA-5696398
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
DNA Damage Recognition in GG-NER R-HSA-5696394
Dual Incision in GG-NER R-HSA-5696400
DNA Repair R-HSA-73894
Resolution of Abasic Sites (AP sites) R-HSA-73933
Formation of Incision Complex in GG-NER R-HSA-5696395
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
DNA Double-Strand Break Repair R-HSA-5693532
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399
DNA Damage Recognition in GG-NER R-HSA-5696394
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362
Homology Directed Repair R-HSA-5693538
Nucleotide Excision Repair R-HSA-5696398
Resolution of Abasic Sites (AP sites) R-HSA-73933
Base Excision Repair R-HSA-73884
DNA Repair R-HSA-73894
HDR through MMEJ (alt-NHEJ) R-HSA-5685939
Formation of Incision Complex in GG-NER R-HSA-5696395
Dual Incision in GG-NER R-HSA-5696400

Expression Atlas ENSG00000129484
NCBI gene (formerly Entrezgene) 10038
GeneCards 272
HGNC Symbol HGNC:272
MIM gene 607725
UniProtKB Gene Name Q9UGN5
WikiGene 10038
Gene: MIF
Ensembl ID : ENSG00000240972
Description: macrophage migration inhibitory factor
Gene Synonyms: GIF,GLIF
2 APIs:
219 Possible Orthologues:

Hemostasis R-HSA-109582
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Interleukin-12 signaling R-HSA-9020591
Immune System R-HSA-168256
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-12 family signaling R-HSA-447115
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Cell surface interactions at the vascular wall R-HSA-202733
Immune System R-HSA-168256
Interleukin-12 signaling R-HSA-9020591
Interleukin-12 family signaling R-HSA-447115
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Cytokine Signaling in Immune system R-HSA-1280215
Hemostasis R-HSA-109582
Signaling by Interleukins R-HSA-449147
Interleukin-12 family signaling R-HSA-447115
Interleukin-12 signaling R-HSA-9020591
Cell surface interactions at the vascular wall R-HSA-202733
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-12 family signaling R-HSA-447115
Interleukin-12 signaling R-HSA-9020591
Cytokine Signaling in Immune system R-HSA-1280215
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Interleukin-12 signaling R-HSA-9020591
Cell surface interactions at the vascular wall R-HSA-202733
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Signaling by Interleukins R-HSA-449147
Hemostasis R-HSA-109582
Interleukin-12 family signaling R-HSA-447115
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Neutrophil degranulation R-HSA-6798695
Cytokine Signaling in Immune system R-HSA-1280215
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-12 signaling R-HSA-9020591
Interleukin-12 family signaling R-HSA-447115
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Hemostasis R-HSA-109582
Signaling by Interleukins R-HSA-449147
Interleukin-12 signaling R-HSA-9020591
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Interleukin-12 family signaling R-HSA-447115
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Hemostasis R-HSA-109582
Innate Immune System R-HSA-168249
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by Interleukins R-HSA-449147
Neutrophil degranulation R-HSA-6798695
Interleukin-12 signaling R-HSA-9020591
Interleukin-12 family signaling R-HSA-447115
Hemostasis R-HSA-109582
Immune System R-HSA-168256
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Innate Immune System R-HSA-168249
Cell surface interactions at the vascular wall R-HSA-202733
Cytokine Signaling in Immune system R-HSA-1280215
Neutrophil degranulation R-HSA-6798695
Signaling by Interleukins R-HSA-449147
Cell surface interactions at the vascular wall R-HSA-202733
Cytokine Signaling in Immune system R-HSA-1280215
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Hemostasis R-HSA-109582
Interleukin-12 signaling R-HSA-9020591
Neutrophil degranulation R-HSA-6798695
Interleukin-12 family signaling R-HSA-447115
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505
Hemostasis R-HSA-109582
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-12 family signaling R-HSA-447115
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Interleukin-12 signaling R-HSA-9020591

Expression Atlas ENSG00000240972
NCBI gene (formerly Entrezgene) 4282
GeneCards 7097
HGNC Symbol HGNC:7097
MIM gene 153620
MIM morbid 604302
UniProtKB Gene Name P14174
WikiGene 4282
Gene: MME
Ensembl ID : ENSG00000196549
Description: membrane metalloendopeptidase
Gene Synonyms: CALLA,CD10,NEP
3 APIs:
236 Possible Orthologues:

Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Peptide hormone metabolism R-HSA-2980736
Physiological factors R-HSA-5578768
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Innate Immune System R-HSA-168249
Cardiac conduction R-HSA-5576891
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Metabolism of proteins R-HSA-392499
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Neutrophil degranulation R-HSA-6798695
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Physiological factors R-HSA-5578768
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Muscle contraction R-HSA-397014
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Neutrophil degranulation R-HSA-6798695
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Physiological factors R-HSA-5578768
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Cardiac conduction R-HSA-5576891
Muscle contraction R-HSA-397014
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Neutrophil degranulation R-HSA-6798695
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Cardiac conduction R-HSA-5576891
Physiological factors R-HSA-5578768
Peptide hormone metabolism R-HSA-2980736
Muscle contraction R-HSA-397014
Muscle contraction R-HSA-397014
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
Physiological factors R-HSA-5578768
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Cardiac conduction R-HSA-5576891
Metabolism of proteins R-HSA-392499
Metabolism of proteins R-HSA-392499
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Immune System R-HSA-168256
Muscle contraction R-HSA-397014
Cardiac conduction R-HSA-5576891
Peptide hormone metabolism R-HSA-2980736
Neutrophil degranulation R-HSA-6798695
Physiological factors R-HSA-5578768
Innate Immune System R-HSA-168249
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Physiological factors R-HSA-5578768
Muscle contraction R-HSA-397014
Metabolism of proteins R-HSA-392499
Peptide hormone metabolism R-HSA-2980736
Cardiac conduction R-HSA-5576891

Expression Atlas ENSG00000196549
NCBI gene (formerly Entrezgene) 4311
GeneCards 7154
HGNC Symbol HGNC:7154
MIM gene 120520
MIM morbid 617018
UniProtKB Gene Name Q3KQS6
WikiGene 4311
Gene: NCSTN
Ensembl ID : ENSG00000162736
Description: nicastrin
Gene Synonyms: APH2,KIAA0253
5 APIs:
204 Possible Orthologues:

Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Death Receptor Signaling R-HSA-73887
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Nervous system development R-HSA-9675108
Amyloid fiber formation R-HSA-977225
Noncanonical activation of NOTCH3 R-HSA-9017802
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulated proteolysis of p75NTR R-HSA-193692
Disease R-HSA-1643685
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Signaling by NOTCH1 R-HSA-1980143
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Neutrophil degranulation R-HSA-6798695
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
Signaling by NOTCH4 R-HSA-9013694
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Immune System R-HSA-168256
Signaling by ERBB4 R-HSA-1236394
Innate Immune System R-HSA-168249
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH4 R-HSA-9013694
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by ERBB4 R-HSA-1236394
Neutrophil degranulation R-HSA-6798695
Amyloid fiber formation R-HSA-977225
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH1 in Cancer R-HSA-2644603
Death Receptor Signaling R-HSA-73887
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Developmental Biology R-HSA-1266738
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Innate Immune System R-HSA-168249
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH3 R-HSA-9012852
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Axon guidance R-HSA-422475
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH R-HSA-157118
Nervous system development R-HSA-9675108
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH3 R-HSA-9012852
EPH-Ephrin signaling R-HSA-2682334
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Degradation of the extracellular matrix R-HSA-1474228
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Death Receptor Signaling R-HSA-73887
Signaling by ERBB4 R-HSA-1236394
Amyloid fiber formation R-HSA-977225
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Nuclear signaling by ERBB4 R-HSA-1251985
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
NRIF signals cell death from the nucleus R-HSA-205043
Metabolism of proteins R-HSA-392499
Signaling by NOTCH R-HSA-157118
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH4 R-HSA-9013694
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH2 R-HSA-1980145
Immune System R-HSA-168256
Signaling by NOTCH1 in Cancer R-HSA-2644603
Axon guidance R-HSA-422475
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Nuclear signaling by ERBB4 R-HSA-1251985
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Axon guidance R-HSA-422475
NRIF signals cell death from the nucleus R-HSA-205043
Signal Transduction R-HSA-162582
p75 NTR receptor-mediated signalling R-HSA-193704
Degradation of the extracellular matrix R-HSA-1474228
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
EPH-Ephrin signaling R-HSA-2682334
Death Receptor Signaling R-HSA-73887
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Amyloid fiber formation R-HSA-977225
Signaling by NOTCH4 R-HSA-9013694
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Developmental Biology R-HSA-1266738
Regulated proteolysis of p75NTR R-HSA-193692
p75 NTR receptor-mediated signalling R-HSA-193704
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Noncanonical activation of NOTCH3 R-HSA-9017802
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Nervous system development R-HSA-9675108
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
NRIF signals cell death from the nucleus R-HSA-205043
Death Receptor Signaling R-HSA-73887
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 R-HSA-1980143
Metabolism of proteins R-HSA-392499
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Developmental Biology R-HSA-1266738
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH4 R-HSA-9013694
Nuclear signaling by ERBB4 R-HSA-1251985
Immune System R-HSA-168256
EPH-Ephrin signaling R-HSA-2682334
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH2 R-HSA-1980145
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Innate Immune System R-HSA-168249
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Amyloid fiber formation R-HSA-977225
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Regulated proteolysis of p75NTR R-HSA-193692
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-Ephrin signaling R-HSA-2682334
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
NRIF signals cell death from the nucleus R-HSA-205043
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH R-HSA-157118
Axon guidance R-HSA-422475
Amyloid fiber formation R-HSA-977225
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Extracellular matrix organization R-HSA-1474244
Immune System R-HSA-168256
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH4 R-HSA-9013694
Developmental Biology R-HSA-1266738
Degradation of the extracellular matrix R-HSA-1474228
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Neutrophil degranulation R-HSA-6798695
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Noncanonical activation of NOTCH3 R-HSA-9017802
p75 NTR receptor-mediated signalling R-HSA-193704
Signaling by NOTCH3 R-HSA-9012852
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by NOTCH1 R-HSA-1980143
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Innate Immune System R-HSA-168249
Nervous system development R-HSA-9675108
p75 NTR receptor-mediated signalling R-HSA-193704
Death Receptor Signaling R-HSA-73887
Noncanonical activation of NOTCH3 R-HSA-9017802
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Metabolism of proteins R-HSA-392499
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Disease R-HSA-1643685
Signaling by NOTCH R-HSA-157118
Signaling by ERBB4 R-HSA-1236394
Signaling by NOTCH4 R-HSA-9013694
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH2 R-HSA-1980145
NRIF signals cell death from the nucleus R-HSA-205043
Amyloid fiber formation R-HSA-977225
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signaling by NOTCH1 in Cancer R-HSA-2644603
Regulated proteolysis of p75NTR R-HSA-193692
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by NOTCH3 R-HSA-9012852
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Extracellular matrix organization R-HSA-1474244
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Degradation of the extracellular matrix R-HSA-1474228
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Immune System R-HSA-168256
p75 NTR receptor-mediated signalling R-HSA-193704
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulated proteolysis of p75NTR R-HSA-193692
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 in Cancer R-HSA-2644603
Amyloid fiber formation R-HSA-977225
Developmental Biology R-HSA-1266738
Signaling by ERBB4 R-HSA-1236394
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH2 R-HSA-1980145
Nervous system development R-HSA-9675108
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Noncanonical activation of NOTCH3 R-HSA-9017802
Axon guidance R-HSA-422475
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
NRIF signals cell death from the nucleus R-HSA-205043
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Neutrophil degranulation R-HSA-6798695
Innate Immune System R-HSA-168249
Signaling by NOTCH4 R-HSA-9013694
Disease R-HSA-1643685
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Signaling by NOTCH1 R-HSA-1980143
Death Receptor Signaling R-HSA-73887
Degradation of the extracellular matrix R-HSA-1474228
Developmental Biology R-HSA-1266738
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
p75 NTR receptor-mediated signalling R-HSA-193704
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH3 R-HSA-9012852
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Noncanonical activation of NOTCH3 R-HSA-9017802
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by ERBB4 R-HSA-1236394
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signaling by NOTCH4 R-HSA-9013694
Regulated proteolysis of p75NTR R-HSA-193692
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH R-HSA-157118
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Extracellular matrix organization R-HSA-1474244
Neutrophil degranulation R-HSA-6798695
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Disease R-HSA-1643685
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Signaling by NOTCH1 in Cancer R-HSA-2644603
Signal Transduction R-HSA-162582
NRIF signals cell death from the nucleus R-HSA-205043
Amyloid fiber formation R-HSA-977225
Nuclear signaling by ERBB4 R-HSA-1251985
Nervous system development R-HSA-9675108
Axon guidance R-HSA-422475
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NOTCH2 R-HSA-1980145
Axon guidance R-HSA-422475
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Innate Immune System R-HSA-168249
Metabolism of proteins R-HSA-392499
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Degradation of the extracellular matrix R-HSA-1474228
Signaling by NOTCH3 R-HSA-9012852
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Death Receptor Signaling R-HSA-73887
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 R-HSA-1980143
Signaling by ERBB4 R-HSA-1236394
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH1 in Cancer R-HSA-2644603
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Disease R-HSA-1643685
Noncanonical activation of NOTCH3 R-HSA-9017802
EPH-ephrin mediated repulsion of cells R-HSA-3928665
p75 NTR receptor-mediated signalling R-HSA-193704
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Signal Transduction R-HSA-162582
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Developmental Biology R-HSA-1266738
Signaling by NOTCH R-HSA-157118
Amyloid fiber formation R-HSA-977225
Nuclear signaling by ERBB4 R-HSA-1251985
Regulated proteolysis of p75NTR R-HSA-193692
Immune System R-HSA-168256
Signaling by NOTCH4 R-HSA-9013694
Extracellular matrix organization R-HSA-1474244
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948
Signaling by NOTCH4 R-HSA-9013694
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998
Noncanonical activation of NOTCH3 R-HSA-9017802
Death Receptor Signaling R-HSA-73887
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606
Amyloid fiber formation R-HSA-977225
Immune System R-HSA-168256
Nervous system development R-HSA-9675108
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096
Degradation of the extracellular matrix R-HSA-1474228
p75 NTR receptor-mediated signalling R-HSA-193704
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Innate Immune System R-HSA-168249
EPH-ephrin mediated repulsion of cells R-HSA-3928665
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602
Signaling by NOTCH1 R-HSA-1980143
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858
Axon guidance R-HSA-422475
Signal Transduction R-HSA-162582
Signaling by NOTCH3 R-HSA-9012852
Signaling by ERBB4 R-HSA-1236394
Metabolism of proteins R-HSA-392499
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862
Developmental Biology R-HSA-1266738
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507
Regulated proteolysis of p75NTR R-HSA-193692
NRIF signals cell death from the nucleus R-HSA-205043
Neutrophil degranulation R-HSA-6798695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPH-Ephrin signaling R-HSA-2682334
Nuclear signaling by ERBB4 R-HSA-1251985
Extracellular matrix organization R-HSA-1474244
Signaling by NOTCH2 R-HSA-1980145
Signaling by NOTCH1 in Cancer R-HSA-2644603

Expression Atlas ENSG00000162736
LRG display in Ensembl gene LRG_223
NCBI gene (formerly Entrezgene) 23385
GeneCards 17091
HGNC Symbol HGNC:17091
MIM gene 605254
MIM morbid 142690
UniProtKB Gene Name Q92542
WikiGene 23385
Gene: CDK5
Ensembl ID : ENSG00000164885
Description: cyclin dependent kinase 5
Gene Synonyms: PSSALRE
3 APIs:
166 Possible Orthologues:

Signaling by NTRKs R-HSA-166520
CRMPs in Sema3A signaling R-HSA-399956
Diseases of programmed cell death R-HSA-9645723
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity R-HSA-5633007
Signal Transduction R-HSA-162582
NPAS4 regulates expression of target genes R-HSA-9768919
Signaling by GPCR R-HSA-372790
Activated NTRK2 signals through CDK5 R-HSA-9032845
Axon guidance R-HSA-422475
Disease R-HSA-1643685
Transcriptional Regulation by NPAS4 R-HSA-9634815
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK2 (TRKB) R-HSA-9006115
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Gene expression (Transcription) R-HSA-74160
Developmental Biology R-HSA-1266738
Signaling by NTRKs R-HSA-166520
Nervous system development R-HSA-9675108
G alpha (i) signalling events R-HSA-418594
DARPP-32 events R-HSA-180024
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Neurodegenerative Diseases R-HSA-8863678
Signaling by NTRK1 (TRKA) R-HSA-187037
CRMPs in Sema3A signaling R-HSA-399956
GPCR downstream signalling R-HSA-388396
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Opioid Signalling R-HSA-111885
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
NGF-stimulated transcription R-HSA-9031628
Transcriptional Regulation by TP53 R-HSA-3700989
Semaphorin interactions R-HSA-373755
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
G alpha (i) signalling events R-HSA-418594
Gene expression (Transcription) R-HSA-74160
Signaling by NTRK1 (TRKA) R-HSA-187037
Opioid Signalling R-HSA-111885
Regulation of TP53 Activity R-HSA-5633007
Hemostasis R-HSA-109582
NGF-stimulated transcription R-HSA-9031628
Diseases of programmed cell death R-HSA-9645723
Nervous system development R-HSA-9675108
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signal Transduction R-HSA-162582
Transcriptional Regulation by TP53 R-HSA-3700989
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
CRMPs in Sema3A signaling R-HSA-399956
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
RNA Polymerase II Transcription R-HSA-73857
Activated NTRK2 signals through CDK5 R-HSA-9032845
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
GPCR downstream signalling R-HSA-388396
DARPP-32 events R-HSA-180024
Transcriptional Regulation by NPAS4 R-HSA-9634815
Semaphorin interactions R-HSA-373755
Disease R-HSA-1643685
Neurodegenerative Diseases R-HSA-8863678
Axon guidance R-HSA-422475
Signaling by NTRK2 (TRKB) R-HSA-9006115
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
Signaling by GPCR R-HSA-372790
Signaling by NTRKs R-HSA-166520
Generic Transcription Pathway R-HSA-212436
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by NTRK2 (TRKB) R-HSA-9006115
Gene expression (Transcription) R-HSA-74160
Transcriptional Regulation by TP53 R-HSA-3700989
Nervous system development R-HSA-9675108
Signaling by GPCR R-HSA-372790
DARPP-32 events R-HSA-180024
Opioid Signalling R-HSA-111885
Generic Transcription Pathway R-HSA-212436
NPAS4 regulates expression of target genes R-HSA-9768919
Diseases of programmed cell death R-HSA-9645723
G alpha (i) signalling events R-HSA-418594
Developmental Biology R-HSA-1266738
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
RNA Polymerase II Transcription R-HSA-73857
Signaling by NTRK1 (TRKA) R-HSA-187037
Axon guidance R-HSA-422475
Disease R-HSA-1643685
CRMPs in Sema3A signaling R-HSA-399956
Signal Transduction R-HSA-162582
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRKs R-HSA-166520
Hemostasis R-HSA-109582
NGF-stimulated transcription R-HSA-9031628
Factors involved in megakaryocyte development and platelet production R-HSA-983231
GPCR downstream signalling R-HSA-388396
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Regulation of TP53 Activity R-HSA-5633007
Neurodegenerative Diseases R-HSA-8863678
Transcriptional Regulation by NPAS4 R-HSA-9634815
Semaphorin interactions R-HSA-373755
Activated NTRK2 signals through CDK5 R-HSA-9032845
Transcriptional Regulation by NPAS4 R-HSA-9634815
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Semaphorin interactions R-HSA-373755
Activated NTRK2 signals through CDK5 R-HSA-9032845
DARPP-32 events R-HSA-180024
Nervous system development R-HSA-9675108
RNA Polymerase II Transcription R-HSA-73857
Axon guidance R-HSA-422475
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Signaling by NTRK1 (TRKA) R-HSA-187037
CRMPs in Sema3A signaling R-HSA-399956
Disease R-HSA-1643685
Diseases of programmed cell death R-HSA-9645723
Gene expression (Transcription) R-HSA-74160
G alpha (i) signalling events R-HSA-418594
Neurodegenerative Diseases R-HSA-8863678
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Generic Transcription Pathway R-HSA-212436
Signaling by GPCR R-HSA-372790
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRK2 (TRKB) R-HSA-9006115
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
NPAS4 regulates expression of target genes R-HSA-9768919
Developmental Biology R-HSA-1266738
Opioid Signalling R-HSA-111885
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
GPCR downstream signalling R-HSA-388396
Signal Transduction R-HSA-162582
NGF-stimulated transcription R-HSA-9031628
Transcriptional Regulation by TP53 R-HSA-3700989
Signal Transduction R-HSA-162582
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRKs R-HSA-166520
Opioid Signalling R-HSA-111885
Factors involved in megakaryocyte development and platelet production R-HSA-983231
CRMPs in Sema3A signaling R-HSA-399956
Regulation of TP53 Activity R-HSA-5633007
Transcriptional Regulation by NPAS4 R-HSA-9634815
Gene expression (Transcription) R-HSA-74160
Neurodegenerative Diseases R-HSA-8863678
Semaphorin interactions R-HSA-373755
G alpha (i) signalling events R-HSA-418594
GPCR downstream signalling R-HSA-388396
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by NTRK1 (TRKA) R-HSA-187037
Generic Transcription Pathway R-HSA-212436
Axon guidance R-HSA-422475
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Activated NTRK2 signals through CDK5 R-HSA-9032845
DARPP-32 events R-HSA-180024
Signaling by GPCR R-HSA-372790
Disease R-HSA-1643685
Diseases of programmed cell death R-HSA-9645723
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRK2 (TRKB) R-HSA-9006115
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Signaling by NTRK2 (TRKB) R-HSA-9006115
Generic Transcription Pathway R-HSA-212436
Semaphorin interactions R-HSA-373755
DARPP-32 events R-HSA-180024
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by GPCR R-HSA-372790
Diseases of programmed cell death R-HSA-9645723
NPAS4 regulates expression of target genes R-HSA-9768919
Neurodegenerative Diseases R-HSA-8863678
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Opioid Signalling R-HSA-111885
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Developmental Biology R-HSA-1266738
Regulation of TP53 Activity R-HSA-5633007
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
G alpha (i) signalling events R-HSA-418594
Hemostasis R-HSA-109582
Disease R-HSA-1643685
NGF-stimulated transcription R-HSA-9031628
RNA Polymerase II Transcription R-HSA-73857
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Activated NTRK2 signals through CDK5 R-HSA-9032845
GPCR downstream signalling R-HSA-388396
Signaling by NTRKs R-HSA-166520
Transcriptional Regulation by NPAS4 R-HSA-9634815
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nervous system development R-HSA-9675108
CRMPs in Sema3A signaling R-HSA-399956
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRKs R-HSA-166520
DARPP-32 events R-HSA-180024
Disease R-HSA-1643685
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Transcriptional Regulation by NPAS4 R-HSA-9634815
Transcriptional Regulation by TP53 R-HSA-3700989
Signal Transduction R-HSA-162582
GPCR downstream signalling R-HSA-388396
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Hemostasis R-HSA-109582
Nervous system development R-HSA-9675108
Factors involved in megakaryocyte development and platelet production R-HSA-983231
CRMPs in Sema3A signaling R-HSA-399956
Activated NTRK2 signals through CDK5 R-HSA-9032845
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Semaphorin interactions R-HSA-373755
Diseases of programmed cell death R-HSA-9645723
Signaling by GPCR R-HSA-372790
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
NPAS4 regulates expression of target genes R-HSA-9768919
Opioid Signalling R-HSA-111885
Signaling by NTRK2 (TRKB) R-HSA-9006115
G alpha (i) signalling events R-HSA-418594
Gene expression (Transcription) R-HSA-74160
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRK1 (TRKA) R-HSA-187037
Developmental Biology R-HSA-1266738
Neurodegenerative Diseases R-HSA-8863678
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
NPAS4 regulates expression of target genes R-HSA-9768919
Transcriptional Regulation by TP53 R-HSA-3700989
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Nervous system development R-HSA-9675108
NGF-stimulated transcription R-HSA-9031628
Signaling by NTRK2 (TRKB) R-HSA-9006115
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Hemostasis R-HSA-109582
Neurodegenerative Diseases R-HSA-8863678
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
Developmental Biology R-HSA-1266738
Activated NTRK2 signals through CDK5 R-HSA-9032845
Regulation of TP53 Activity R-HSA-5633007
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by GPCR R-HSA-372790
Generic Transcription Pathway R-HSA-212436
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
DARPP-32 events R-HSA-180024
Transcriptional Regulation by NPAS4 R-HSA-9634815
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
G alpha (i) signalling events R-HSA-418594
CRMPs in Sema3A signaling R-HSA-399956
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
Signaling by NTRKs R-HSA-166520
Axon guidance R-HSA-422475
Semaphorin interactions R-HSA-373755
Diseases of programmed cell death R-HSA-9645723
NGF-stimulated transcription R-HSA-9031628
G alpha (i) signalling events R-HSA-418594
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Transcriptional Regulation by NPAS4 R-HSA-9634815
Diseases of programmed cell death R-HSA-9645723
Signaling by NTRK2 (TRKB) R-HSA-9006115
CRMPs in Sema3A signaling R-HSA-399956
RNA Polymerase II Transcription R-HSA-73857
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signal Transduction R-HSA-162582
Signaling by NTRK1 (TRKA) R-HSA-187037
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
NPAS4 regulates expression of target genes R-HSA-9768919
Axon guidance R-HSA-422475
Opioid Signalling R-HSA-111885
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Regulation of TP53 Activity R-HSA-5633007
Activated NTRK2 signals through CDK5 R-HSA-9032845
Generic Transcription Pathway R-HSA-212436
Neurodegenerative Diseases R-HSA-8863678
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Hemostasis R-HSA-109582
Signaling by NTRKs R-HSA-166520
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
Gene expression (Transcription) R-HSA-74160
DARPP-32 events R-HSA-180024
Disease R-HSA-1643685
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
NGF-stimulated transcription R-HSA-9031628
RNA Polymerase II Transcription R-HSA-73857
G alpha (i) signalling events R-HSA-418594
Axon guidance R-HSA-422475
Neurodegenerative Diseases R-HSA-8863678
DARPP-32 events R-HSA-180024
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Signaling by NTRK2 (TRKB) R-HSA-9006115
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Activity R-HSA-5633007
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
CRMPs in Sema3A signaling R-HSA-399956
Disease R-HSA-1643685
Activated NTRK2 signals through CDK5 R-HSA-9032845
Opioid Signalling R-HSA-111885
Gene expression (Transcription) R-HSA-74160
GPCR downstream signalling R-HSA-388396
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Transcriptional Regulation by NPAS4 R-HSA-9634815
Diseases of programmed cell death R-HSA-9645723
Generic Transcription Pathway R-HSA-212436
Signaling by NTRK1 (TRKA) R-HSA-187037
Nervous system development R-HSA-9675108
NPAS4 regulates expression of target genes R-HSA-9768919
Hemostasis R-HSA-109582
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Regulation of TP53 Activity R-HSA-5633007
Developmental Biology R-HSA-1266738
Signaling by GPCR R-HSA-372790
Nervous system development R-HSA-9675108
Signaling by NTRK1 (TRKA) R-HSA-187037
Gene expression (Transcription) R-HSA-74160
Axon guidance R-HSA-422475
Generic Transcription Pathway R-HSA-212436
DARPP-32 events R-HSA-180024
Hemostasis R-HSA-109582
Activated NTRK2 signals through CDK5 R-HSA-9032845
Signaling by NTRK2 (TRKB) R-HSA-9006115
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Nuclear Events (kinase and transcription factor activation) R-HSA-198725
Transcriptional Regulation by NPAS4 R-HSA-9634815
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Opioid Signalling R-HSA-111885
GPCR downstream signalling R-HSA-388396
NPAS4 regulates expression of target genes R-HSA-9768919
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803
Diseases of programmed cell death R-HSA-9645723
Semaphorin interactions R-HSA-373755
Signaling by NTRKs R-HSA-166520
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Neurodegenerative Diseases R-HSA-8863678
NGF-stimulated transcription R-HSA-9031628
Disease R-HSA-1643685
G alpha (i) signalling events R-HSA-418594
Transcriptional Regulation by TP53 R-HSA-3700989
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000164885
NCBI gene (formerly Entrezgene) 1020
GeneCards 1774
HGNC Symbol HGNC:1774
MIM gene 123831
MIM morbid 616342
UniProtKB Gene Name Q00535
WikiGene 1020
Gene: HMGCR
Ensembl ID : ENSG00000113161
Description: 3-hydroxy-3-methylglutaryl-CoA reductase
Gene Synonyms:
10 APIs:
272 Possible Orthologues:

PPARA activates gene expression R-HSA-1989781
Cholesterol biosynthesis R-HSA-191273
Metabolism of steroids R-HSA-8957322
Nervous system development R-HSA-9675108
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Developmental Biology R-HSA-1266738
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cholesterol biosynthesis R-HSA-191273
Developmental Biology R-HSA-1266738
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
Nervous system development R-HSA-9675108
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism of lipids R-HSA-556833
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
Cholesterol biosynthesis R-HSA-191273
Nervous system development R-HSA-9675108
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
PPARA activates gene expression R-HSA-1989781
Developmental Biology R-HSA-1266738
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of steroids R-HSA-8957322
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism of lipids R-HSA-556833
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Metabolism R-HSA-1430728
Nervous system development R-HSA-9675108
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Developmental Biology R-HSA-1266738
PPARA activates gene expression R-HSA-1989781
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
Developmental Biology R-HSA-1266738
Cholesterol biosynthesis R-HSA-191273
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Nervous system development R-HSA-9675108
Metabolism of lipids R-HSA-556833
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism R-HSA-1430728
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Developmental Biology R-HSA-1266738
Metabolism of lipids R-HSA-556833
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Nervous system development R-HSA-9675108
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Nervous system development R-HSA-9675108
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
Cholesterol biosynthesis R-HSA-191273
PPARA activates gene expression R-HSA-1989781
Metabolism of lipids R-HSA-556833
Developmental Biology R-HSA-1266738
Metabolism of lipids R-HSA-556833
Developmental Biology R-HSA-1266738
Metabolism R-HSA-1430728
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Nervous system development R-HSA-9675108
Metabolism of steroids R-HSA-8957322
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of steroids R-HSA-8957322
Nervous system development R-HSA-9675108
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Developmental Biology R-HSA-1266738
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273

Expression Atlas ENSG00000113161
NCBI gene (formerly Entrezgene) 3156
GeneCards 5006
HGNC Symbol HGNC:5006
MIM gene 142910
MIM morbid 142910
UniProtKB Gene Name P04035
WikiGene 3156