Gene: BCHE
Ensembl ID : ENSG00000114200
Description: butyrylcholinesterase
Gene Synonyms: CHE1,CHE2,E1
1 APIs:
130 Possible Orthologues:

Metabolism of proteins R-HSA-392499
Transmission across Chemical Synapses R-HSA-112315
Drug ADME R-HSA-9748784
Glycerophospholipid biosynthesis R-HSA-1483206
Phospholipid metabolism R-HSA-1483257
Metabolism of lipids R-HSA-556833
Neurotransmitter clearance R-HSA-112311
Peptide hormone metabolism R-HSA-2980736
Synthesis of PC R-HSA-1483191
Aspirin ADME R-HSA-9749641
Neuronal System R-HSA-112316
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Metabolism R-HSA-1430728
Glycerophospholipid biosynthesis R-HSA-1483206
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Transmission across Chemical Synapses R-HSA-112315
Metabolism of lipids R-HSA-556833
Peptide hormone metabolism R-HSA-2980736
Aspirin ADME R-HSA-9749641
Metabolism of proteins R-HSA-392499
Phospholipid metabolism R-HSA-1483257
Neuronal System R-HSA-112316
Synthesis of PC R-HSA-1483191
Metabolism R-HSA-1430728
Neurotransmitter clearance R-HSA-112311
Drug ADME R-HSA-9748784
Transmission across Chemical Synapses R-HSA-112315
Aspirin ADME R-HSA-9749641
Peptide hormone metabolism R-HSA-2980736
Phospholipid metabolism R-HSA-1483257
Neurotransmitter clearance R-HSA-112311
Drug ADME R-HSA-9748784
Metabolism R-HSA-1430728
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Metabolism of proteins R-HSA-392499
Metabolism of lipids R-HSA-556833
Synthesis of PC R-HSA-1483191
Neuronal System R-HSA-112316
Glycerophospholipid biosynthesis R-HSA-1483206
Transmission across Chemical Synapses R-HSA-112315
Aspirin ADME R-HSA-9749641
Neurotransmitter clearance R-HSA-112311
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Drug ADME R-HSA-9748784
Glycerophospholipid biosynthesis R-HSA-1483206
Synthesis of PC R-HSA-1483191
Metabolism of proteins R-HSA-392499
Neuronal System R-HSA-112316
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Phospholipid metabolism R-HSA-1483257
Peptide hormone metabolism R-HSA-2980736
Neuronal System R-HSA-112316
Neurotransmitter clearance R-HSA-112311
Drug ADME R-HSA-9748784
Aspirin ADME R-HSA-9749641
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Transmission across Chemical Synapses R-HSA-112315
Glycerophospholipid biosynthesis R-HSA-1483206
Synthesis of PC R-HSA-1483191
Peptide hormone metabolism R-HSA-2980736
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Metabolism of proteins R-HSA-392499
Phospholipid metabolism R-HSA-1483257
Metabolism R-HSA-1430728
Phospholipid metabolism R-HSA-1483257
Metabolism of lipids R-HSA-556833
Neurotransmitter clearance R-HSA-112311
Neuronal System R-HSA-112316
Synthesis of PC R-HSA-1483191
Glycerophospholipid biosynthesis R-HSA-1483206
Peptide hormone metabolism R-HSA-2980736
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Drug ADME R-HSA-9748784
Transmission across Chemical Synapses R-HSA-112315
Aspirin ADME R-HSA-9749641
Metabolism of proteins R-HSA-392499
Phospholipid metabolism R-HSA-1483257
Glycerophospholipid biosynthesis R-HSA-1483206
Metabolism of proteins R-HSA-392499
Drug ADME R-HSA-9748784
Peptide hormone metabolism R-HSA-2980736
Metabolism of lipids R-HSA-556833
Synthesis of PC R-HSA-1483191
Aspirin ADME R-HSA-9749641
Metabolism R-HSA-1430728
Transmission across Chemical Synapses R-HSA-112315
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Neuronal System R-HSA-112316
Neurotransmitter clearance R-HSA-112311
Peptide hormone metabolism R-HSA-2980736
Neurotransmitter clearance R-HSA-112311
Synthesis of PC R-HSA-1483191
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Neuronal System R-HSA-112316
Glycerophospholipid biosynthesis R-HSA-1483206
Drug ADME R-HSA-9748784
Metabolism of proteins R-HSA-392499
Metabolism R-HSA-1430728
Phospholipid metabolism R-HSA-1483257
Aspirin ADME R-HSA-9749641
Metabolism of lipids R-HSA-556833
Transmission across Chemical Synapses R-HSA-112315
Metabolism of proteins R-HSA-392499
Glycerophospholipid biosynthesis R-HSA-1483206
Metabolism of lipids R-HSA-556833
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Drug ADME R-HSA-9748784
Neuronal System R-HSA-112316
Neurotransmitter clearance R-HSA-112311
Peptide hormone metabolism R-HSA-2980736
Metabolism R-HSA-1430728
Aspirin ADME R-HSA-9749641
Synthesis of PC R-HSA-1483191
Phospholipid metabolism R-HSA-1483257
Transmission across Chemical Synapses R-HSA-112315
Phospholipid metabolism R-HSA-1483257
Metabolism R-HSA-1430728
Neurotransmitter clearance R-HSA-112311
Synthesis of PC R-HSA-1483191
Glycerophospholipid biosynthesis R-HSA-1483206
Metabolism of lipids R-HSA-556833
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Neuronal System R-HSA-112316
Metabolism of proteins R-HSA-392499
Aspirin ADME R-HSA-9749641
Peptide hormone metabolism R-HSA-2980736
Transmission across Chemical Synapses R-HSA-112315
Drug ADME R-HSA-9748784
Synthesis of PC R-HSA-1483191
Aspirin ADME R-HSA-9749641
Neurotransmitter clearance R-HSA-112311
Neuronal System R-HSA-112316
Phospholipid metabolism R-HSA-1483257
Metabolism of lipids R-HSA-556833
Glycerophospholipid biosynthesis R-HSA-1483206
Metabolism R-HSA-1430728
Peptide hormone metabolism R-HSA-2980736
Metabolism of proteins R-HSA-392499
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085
Drug ADME R-HSA-9748784
Transmission across Chemical Synapses R-HSA-112315

Expression Atlas ENSG00000114200
NCBI gene (formerly Entrezgene) 590
GeneCards 983
HGNC Symbol HGNC:983
MIM gene 177400
MIM morbid 617936
UniProtKB Gene Name P06276
WikiGene 590
Gene: CDK2
Ensembl ID : ENSG00000123374
Description: cyclin dependent kinase 2
Gene Synonyms:
11 APIs:
203 Possible Orthologues:

G2/M Transition R-HSA-69275
G2 Phase R-HSA-68911
Regulation of mitotic cell cycle R-HSA-453276
PTK6 Regulates Cell Cycle R-HSA-8849470
RNA Polymerase II Transcription R-HSA-73857
S Phase R-HSA-69242
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Generic Transcription Pathway R-HSA-212436
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hemostasis R-HSA-109582
Signal Transduction R-HSA-162582
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
Chromosome Maintenance R-HSA-73886
G1/S DNA Damage Checkpoints R-HSA-69615
DNA Double-Strand Break Repair R-HSA-5693532
DNA Replication Pre-Initiation R-HSA-69002
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
DNA Repair R-HSA-73894
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stress R-HSA-2262752
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of TP53 Degradation R-HSA-6804757
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Switching of origins to a post-replicative state R-HSA-69052
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G2/M Transition R-HSA-69275
G0 and Early G1 R-HSA-1538133
Diseases of mitotic cell cycle R-HSA-9675126
Cyclin D associated events in G1 R-HSA-69231
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Developmental Biology R-HSA-1266738
Transcriptional regulation of granulopoiesis R-HSA-9616222
G1/S Transition R-HSA-69206
Meiosis R-HSA-1500620
Mitotic G2-G2/M phases R-HSA-453274
Regulation of TP53 Activity R-HSA-5633007
Telomere Maintenance R-HSA-157579
Meiotic recombination R-HSA-912446
Cellular Senescence R-HSA-2559583
Cell Cycle Checkpoints R-HSA-69620
Telomere Extension By Telomerase R-HSA-171319
Orc1 removal from chromatin R-HSA-68949
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Disease R-HSA-1643685
G2 Phase R-HSA-68911
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by PTK6 R-HSA-8848021
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Processing of DNA double-strand break ends R-HSA-5693607
Regulation of TP53 Expression and Degradation R-HSA-6806003
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Reproduction R-HSA-1474165
G1 Phase R-HSA-69236
G2/M Checkpoints R-HSA-69481
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cell Cycle R-HSA-1640170
Homology Directed Repair R-HSA-5693538
Cell Cycle, Mitotic R-HSA-69278
Activation of ATR in response to replication stress R-HSA-176187
Gene expression (Transcription) R-HSA-74160
Extension of Telomeres R-HSA-180786
Telomere Maintenance R-HSA-157579
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Reproduction R-HSA-1474165
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by PTK6 R-HSA-8848021
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Degradation R-HSA-6804757
Cyclin D associated events in G1 R-HSA-69231
G0 and Early G1 R-HSA-1538133
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G1/S DNA Damage Checkpoints R-HSA-69615
Extension of Telomeres R-HSA-180786
Synthesis of DNA R-HSA-69239
DNA Repair R-HSA-73894
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Replication R-HSA-69306
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
p53-Dependent G1 DNA Damage Response R-HSA-69563
Developmental Biology R-HSA-1266738
Diseases of mitotic cell cycle R-HSA-9675126
Disease R-HSA-1643685
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G2-G2/M phases R-HSA-453274
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
Cellular responses to stress R-HSA-2262752
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Meiotic recombination R-HSA-912446
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation of granulopoiesis R-HSA-9616222
PTK6 Regulates Cell Cycle R-HSA-8849470
Cyclin E associated events during G1/S transition R-HSA-69202
Processing of DNA double-strand break ends R-HSA-5693607
Orc1 removal from chromatin R-HSA-68949
Switching of origins to a post-replicative state R-HSA-69052
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Meiosis R-HSA-1500620
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Homology Directed Repair R-HSA-5693538
Activation of the pre-replicative complex R-HSA-68962
G2 Phase R-HSA-68911
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
RNA Polymerase II Transcription R-HSA-73857
Telomere Extension By Telomerase R-HSA-171319
DNA Double-Strand Break Repair R-HSA-5693532
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
S Phase R-HSA-69242
Cell Cycle, Mitotic R-HSA-69278
Activation of ATR in response to replication stress R-HSA-176187
Cellular Senescence R-HSA-2559583
Chromosome Maintenance R-HSA-73886
G1/S Transition R-HSA-69206
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
DNA Replication Pre-Initiation R-HSA-69002
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hemostasis R-HSA-109582
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
G1 Phase R-HSA-69236
Gene expression (Transcription) R-HSA-74160
Signal Transduction R-HSA-162582
Cell Cycle Checkpoints R-HSA-69620
G0 and Early G1 R-HSA-1538133
Meiotic recombination R-HSA-912446
G2/M Checkpoints R-HSA-69481
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Developmental Biology R-HSA-1266738
Hemostasis R-HSA-109582
Generic Transcription Pathway R-HSA-212436
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Cyclin E associated events during G1/S transition R-HSA-69202
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Mitotic G2-G2/M phases R-HSA-453274
PTK6 Regulates Cell Cycle R-HSA-8849470
G1 Phase R-HSA-69236
Signal Transduction R-HSA-162582
Orc1 removal from chromatin R-HSA-68949
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of mitotic cell cycle R-HSA-453276
S Phase R-HSA-69242
Telomere Extension By Telomerase R-HSA-171319
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Signaling by PTK6 R-HSA-8848021
DNA Replication R-HSA-69306
G1/S Transition R-HSA-69206
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of ATR in response to replication stress R-HSA-176187
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle Checkpoints R-HSA-69620
Processing of DNA double-strand break ends R-HSA-5693607
Gene expression (Transcription) R-HSA-74160
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional Regulation by TP53 R-HSA-3700989
Meiosis R-HSA-1500620
Disease R-HSA-1643685
Switching of origins to a post-replicative state R-HSA-69052
Cyclin D associated events in G1 R-HSA-69231
p53-Dependent G1 DNA Damage Response R-HSA-69563
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Transition R-HSA-69275
Activation of the pre-replicative complex R-HSA-68962
Regulation of TP53 Degradation R-HSA-6804757
DNA Repair R-HSA-73894
RNA Polymerase II Transcription R-HSA-73857
Telomere Maintenance R-HSA-157579
Diseases of mitotic cell cycle R-HSA-9675126
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stimuli R-HSA-8953897
Chromosome Maintenance R-HSA-73886
Extension of Telomeres R-HSA-180786
Homology Directed Repair R-HSA-5693538
Cell Cycle, Mitotic R-HSA-69278
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
DNA Double-Strand Break Repair R-HSA-5693532
Reproduction R-HSA-1474165
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Regulation of TP53 Activity R-HSA-5633007
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Transcriptional regulation of granulopoiesis R-HSA-9616222
Cell Cycle R-HSA-1640170
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular responses to stress R-HSA-2262752
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Synthesis of DNA R-HSA-69239
Regulation of TP53 Expression and Degradation R-HSA-6806003
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Diseases of mitotic cell cycle R-HSA-9675126
DNA Double-Strand Break Repair R-HSA-5693532
Cellular responses to stimuli R-HSA-8953897
Reproduction R-HSA-1474165
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signal Transduction R-HSA-162582
Cyclin D associated events in G1 R-HSA-69231
Transcriptional regulation of granulopoiesis R-HSA-9616222
DNA Repair R-HSA-73894
Gene expression (Transcription) R-HSA-74160
G2/M Checkpoints R-HSA-69481
Cell Cycle, Mitotic R-HSA-69278
Extension of Telomeres R-HSA-180786
G0 and Early G1 R-HSA-1538133
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
G1/S Transition R-HSA-69206
G2 Phase R-HSA-68911
Cell Cycle R-HSA-1640170
Meiotic recombination R-HSA-912446
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Mitotic G1 phase and G1/S transition R-HSA-453279
G1 Phase R-HSA-69236
Developmental Biology R-HSA-1266738
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
G1/S DNA Damage Checkpoints R-HSA-69615
Processing of DNA double-strand break ends R-HSA-5693607
Telomere Maintenance R-HSA-157579
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Chromosome Maintenance R-HSA-73886
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Signaling by PTK6 R-HSA-8848021
Cellular Senescence R-HSA-2559583
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Synthesis of DNA R-HSA-69239
Cell Cycle Checkpoints R-HSA-69620
Regulation of TP53 Degradation R-HSA-6804757
Cyclin E associated events during G1/S transition R-HSA-69202
Hemostasis R-HSA-109582
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Meiosis R-HSA-1500620
Telomere Extension By Telomerase R-HSA-171319
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Activation of ATR in response to replication stress R-HSA-176187
Orc1 removal from chromatin R-HSA-68949
Activation of the pre-replicative complex R-HSA-68962
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
PTK6 Regulates Cell Cycle R-HSA-8849470
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
S Phase R-HSA-69242
DNA Replication Pre-Initiation R-HSA-69002
Disease R-HSA-1643685
Regulation of mitotic cell cycle R-HSA-453276
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity R-HSA-5633007
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
G2/M Transition R-HSA-69275
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Switching of origins to a post-replicative state R-HSA-69052
RNA Polymerase II Transcription R-HSA-73857
Mitotic G2-G2/M phases R-HSA-453274
DNA Replication R-HSA-69306
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Homology Directed Repair R-HSA-5693538
Cellular responses to stress R-HSA-2262752
Activation of the pre-replicative complex R-HSA-68962
Cyclin D associated events in G1 R-HSA-69231
Developmental Biology R-HSA-1266738
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Mitotic G1 phase and G1/S transition R-HSA-453279
G2 Phase R-HSA-68911
DNA Repair R-HSA-73894
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
Meiotic recombination R-HSA-912446
Processing of DNA double-strand break ends R-HSA-5693607
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Extension of Telomeres R-HSA-180786
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
S Phase R-HSA-69242
Meiosis R-HSA-1500620
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional Regulation by TP53 R-HSA-3700989
G1/S DNA Damage Checkpoints R-HSA-69615
Telomere Extension By Telomerase R-HSA-171319
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Switching of origins to a post-replicative state R-HSA-69052
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle, Mitotic R-HSA-69278
Synthesis of DNA R-HSA-69239
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Orc1 removal from chromatin R-HSA-68949
Cellular responses to stress R-HSA-2262752
Reproduction R-HSA-1474165
Cell Cycle Checkpoints R-HSA-69620
Signaling by PTK6 R-HSA-8848021
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Activation of ATR in response to replication stress R-HSA-176187
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
DNA Replication R-HSA-69306
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Telomere Maintenance R-HSA-157579
Chromosome Maintenance R-HSA-73886
G1 Phase R-HSA-69236
Regulation of TP53 Degradation R-HSA-6804757
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Disease R-HSA-1643685
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
G2/M Transition R-HSA-69275
PTK6 Regulates Cell Cycle R-HSA-8849470
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Hemostasis R-HSA-109582
G2/M Checkpoints R-HSA-69481
Mitotic G2-G2/M phases R-HSA-453274
Cellular responses to stimuli R-HSA-8953897
Homology Directed Repair R-HSA-5693538
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Regulation of mitotic cell cycle R-HSA-453276
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Diseases of mitotic cell cycle R-HSA-9675126
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
G1/S Transition R-HSA-69206
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation of granulopoiesis R-HSA-9616222
Cyclin E associated events during G1/S transition R-HSA-69202
G0 and Early G1 R-HSA-1538133
Signal Transduction R-HSA-162582
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Orc1 removal from chromatin R-HSA-68949
Cyclin E associated events during G1/S transition R-HSA-69202
Meiosis R-HSA-1500620
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Cell Cycle R-HSA-1640170
Telomere Maintenance R-HSA-157579
Reproduction R-HSA-1474165
DNA Double-Strand Break Repair R-HSA-5693532
G2/M Transition R-HSA-69275
Switching of origins to a post-replicative state R-HSA-69052
p53-Dependent G1 DNA Damage Response R-HSA-69563
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Disease R-HSA-1643685
G1 Phase R-HSA-69236
S Phase R-HSA-69242
Developmental Biology R-HSA-1266738
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Diseases of mitotic cell cycle R-HSA-9675126
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
PTK6 Regulates Cell Cycle R-HSA-8849470
Hemostasis R-HSA-109582
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular responses to stimuli R-HSA-8953897
Telomere Extension By Telomerase R-HSA-171319
G2/M Checkpoints R-HSA-69481
Synthesis of DNA R-HSA-69239
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
DNA Replication R-HSA-69306
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Chromosome Maintenance R-HSA-73886
DNA Replication Pre-Initiation R-HSA-69002
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional regulation of granulopoiesis R-HSA-9616222
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Extension of Telomeres R-HSA-180786
Processing of DNA double-strand break ends R-HSA-5693607
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Homology Directed Repair R-HSA-5693538
Signal Transduction R-HSA-162582
G0 and Early G1 R-HSA-1538133
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Regulation of mitotic cell cycle R-HSA-453276
Regulation of TP53 Degradation R-HSA-6804757
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Meiotic recombination R-HSA-912446
DNA Repair R-HSA-73894
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cyclin D associated events in G1 R-HSA-69231
Mitotic G2-G2/M phases R-HSA-453274
Generic Transcription Pathway R-HSA-212436
Cell Cycle, Mitotic R-HSA-69278
G1/S Transition R-HSA-69206
G2 Phase R-HSA-68911
Activation of ATR in response to replication stress R-HSA-176187
Signaling by PTK6 R-HSA-8848021
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Cellular responses to stress R-HSA-2262752
Activation of the pre-replicative complex R-HSA-68962
Regulation of TP53 Expression and Degradation R-HSA-6806003
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Diseases of mitotic cell cycle R-HSA-9675126
Activation of ATR in response to replication stress R-HSA-176187
Chromosome Maintenance R-HSA-73886
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Cellular Senescence R-HSA-2559583
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cyclin E associated events during G1/S transition R-HSA-69202
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
DNA Repair R-HSA-73894
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
G0 and Early G1 R-HSA-1538133
PTK6 Regulates Cell Cycle R-HSA-8849470
Orc1 removal from chromatin R-HSA-68949
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cellular responses to stress R-HSA-2262752
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Disease R-HSA-1643685
Regulation of TP53 Degradation R-HSA-6804757
S Phase R-HSA-69242
Generic Transcription Pathway R-HSA-212436
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Processing of DNA double-strand break ends R-HSA-5693607
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cyclin D associated events in G1 R-HSA-69231
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
DNA Replication R-HSA-69306
Synthesis of DNA R-HSA-69239
Regulation of TP53 Activity R-HSA-5633007
G1 Phase R-HSA-69236
Telomere Maintenance R-HSA-157579
DNA Double-Strand Break Repair R-HSA-5693532
Regulation of mitotic cell cycle R-HSA-453276
Meiosis R-HSA-1500620
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Meiotic recombination R-HSA-912446
Activation of the pre-replicative complex R-HSA-68962
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Cell Cycle R-HSA-1640170
Hemostasis R-HSA-109582
DNA Replication Pre-Initiation R-HSA-69002
G2 Phase R-HSA-68911
G2/M Transition R-HSA-69275
Transcriptional regulation of granulopoiesis R-HSA-9616222
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
p53-Dependent G1 DNA Damage Response R-HSA-69563
Reproduction R-HSA-1474165
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Regulation of TP53 Expression and Degradation R-HSA-6806003
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
Transcriptional Regulation by TP53 R-HSA-3700989
Telomere Extension By Telomerase R-HSA-171319
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Switching of origins to a post-replicative state R-HSA-69052
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Mitotic G1 phase and G1/S transition R-HSA-453279
Homology Directed Repair R-HSA-5693538
G2/M Checkpoints R-HSA-69481
Extension of Telomeres R-HSA-180786
Cellular responses to stimuli R-HSA-8953897
Signaling by PTK6 R-HSA-8848021
PTK6 Regulates Cell Cycle R-HSA-8849470
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Mitotic G1 phase and G1/S transition R-HSA-453279
p53-Dependent G1 DNA Damage Response R-HSA-69563
Extension of Telomeres R-HSA-180786
Cyclin D associated events in G1 R-HSA-69231
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Orc1 removal from chromatin R-HSA-68949
Cellular responses to stimuli R-HSA-8953897
Regulation of mitotic cell cycle R-HSA-453276
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle, Mitotic R-HSA-69278
G0 and Early G1 R-HSA-1538133
Mitotic G2-G2/M phases R-HSA-453274
Activation of ATR in response to replication stress R-HSA-176187
Homology Directed Repair R-HSA-5693538
Meiosis R-HSA-1500620
Synthesis of DNA R-HSA-69239
Cyclin E associated events during G1/S transition R-HSA-69202
G1 Phase R-HSA-69236
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Transcriptional regulation of granulopoiesis R-HSA-9616222
Regulation of TP53 Degradation R-HSA-6804757
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
DNA Replication R-HSA-69306
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Switching of origins to a post-replicative state R-HSA-69052
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hemostasis R-HSA-109582
Cell Cycle R-HSA-1640170
G2/M Transition R-HSA-69275
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
DNA Double-Strand Break Repair R-HSA-5693532
Chromosome Maintenance R-HSA-73886
Signal Transduction R-HSA-162582
Diseases of mitotic cell cycle R-HSA-9675126
Reproduction R-HSA-1474165
Signaling by PTK6 R-HSA-8848021
Telomere Maintenance R-HSA-157579
S Phase R-HSA-69242
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
DNA Repair R-HSA-73894
G2 Phase R-HSA-68911
Cellular Senescence R-HSA-2559583
G1/S Transition R-HSA-69206
Telomere Extension By Telomerase R-HSA-171319
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
Meiotic recombination R-HSA-912446
Cell Cycle Checkpoints R-HSA-69620
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
RNA Polymerase II Transcription R-HSA-73857
Processing of DNA double-strand break ends R-HSA-5693607
G1/S DNA Damage Checkpoints R-HSA-69615
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Activation of the pre-replicative complex R-HSA-68962
G2/M Checkpoints R-HSA-69481
Regulation of TP53 Activity R-HSA-5633007
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
G2/M Transition R-HSA-69275
Mitotic G1 phase and G1/S transition R-HSA-453279
Hemostasis R-HSA-109582
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
G2/M Checkpoints R-HSA-69481
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
S Phase R-HSA-69242
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
Diseases of mitotic cell cycle R-HSA-9675126
Cell Cycle, Mitotic R-HSA-69278
Reproduction R-HSA-1474165
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
Synthesis of DNA R-HSA-69239
DNA Replication R-HSA-69306
Gene expression (Transcription) R-HSA-74160
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Activation of ATR in response to replication stress R-HSA-176187
Cyclin E associated events during G1/S transition R-HSA-69202
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of TP53 Expression and Degradation R-HSA-6806003
Regulation of TP53 Degradation R-HSA-6804757
G0 and Early G1 R-HSA-1538133
Transcriptional regulation of granulopoiesis R-HSA-9616222
DNA Repair R-HSA-73894
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
G1 Phase R-HSA-69236
Regulation of TP53 Activity R-HSA-5633007
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Chromosome Maintenance R-HSA-73886
Orc1 removal from chromatin R-HSA-68949
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Extension of Telomeres R-HSA-180786
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Regulation of mitotic cell cycle R-HSA-453276
Activation of the pre-replicative complex R-HSA-68962
Transcriptional Regulation by TP53 R-HSA-3700989
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Cell Cycle R-HSA-1640170
Signaling by PTK6 R-HSA-8848021
Developmental Biology R-HSA-1266738
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Cellular Senescence R-HSA-2559583
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Switching of origins to a post-replicative state R-HSA-69052
Disease R-HSA-1643685
p53-Dependent G1 DNA Damage Response R-HSA-69563
Mitotic G2-G2/M phases R-HSA-453274
Meiosis R-HSA-1500620
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
DNA Double-Strand Break Repair R-HSA-5693532
Telomere Maintenance R-HSA-157579
Cyclin D associated events in G1 R-HSA-69231
Homology Directed Repair R-HSA-5693538
G2 Phase R-HSA-68911
G1/S Transition R-HSA-69206
PTK6 Regulates Cell Cycle R-HSA-8849470
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Signal Transduction R-HSA-162582
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
DNA Replication Pre-Initiation R-HSA-69002
Generic Transcription Pathway R-HSA-212436
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular responses to stress R-HSA-2262752
Telomere Extension By Telomerase R-HSA-171319
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cellular responses to stimuli R-HSA-8953897
Meiotic recombination R-HSA-912446
Processing of DNA double-strand break ends R-HSA-5693607
G1/S DNA Damage Checkpoints R-HSA-69615
G1 Phase R-HSA-69236
Cellular responses to stress R-HSA-2262752
G2/M Transition R-HSA-69275
Orc1 removal from chromatin R-HSA-68949
Diseases of mitotic cell cycle R-HSA-9675126
Regulation of TP53 Degradation R-HSA-6804757
Cyclin D associated events in G1 R-HSA-69231
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
PTK6 Regulates Cell Cycle R-HSA-8849470
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulation of mitotic cell cycle R-HSA-453276
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Reproduction R-HSA-1474165
Extension of Telomeres R-HSA-180786
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Mitotic G1 phase and G1/S transition R-HSA-453279
Cellular Senescence R-HSA-2559583
Switching of origins to a post-replicative state R-HSA-69052
Hemostasis R-HSA-109582
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Activation of the pre-replicative complex R-HSA-68962
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
G1/S DNA Damage Checkpoints R-HSA-69615
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
DNA Repair R-HSA-73894
Regulation of TP53 Expression and Degradation R-HSA-6806003
G0 and Early G1 R-HSA-1538133
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069
DNA Double-Strand Break Repair R-HSA-5693532
Meiosis R-HSA-1500620
G2 Phase R-HSA-68911
Homology Directed Repair R-HSA-5693538
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139
Cell Cycle R-HSA-1640170
Meiotic recombination R-HSA-912446
Telomere Extension By Telomerase R-HSA-171319
RNA Polymerase II Transcription R-HSA-73857
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S Transition R-HSA-69206
Activation of ATR in response to replication stress R-HSA-176187
DNA Replication R-HSA-69306
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Mitotic G2-G2/M phases R-HSA-453274
Telomere Maintenance R-HSA-157579
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567
Developmental Biology R-HSA-1266738
Signaling by PTK6 R-HSA-8848021
Generic Transcription Pathway R-HSA-212436
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787
Disease R-HSA-1643685
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Synthesis of DNA R-HSA-69239
Chromosome Maintenance R-HSA-73886
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by TP53 R-HSA-3700989
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
DNA Replication Pre-Initiation R-HSA-69002
S Phase R-HSA-69242
Transcriptional regulation of granulopoiesis R-HSA-9616222
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Processing of DNA double-strand break ends R-HSA-5693607
Cell Cycle, Mitotic R-HSA-69278

Expression Atlas ENSG00000123374
NCBI gene (formerly Entrezgene) 1017
GeneCards 1771
HGNC Symbol HGNC:1771
MIM gene 116953
UniProtKB Gene Name P24941
WikiGene 1017
Gene: MALT1
Ensembl ID : ENSG00000172175
Description: MALT1 paracaspase
Gene Synonyms: MLT,PCASP1
1 APIs:
197 Possible Orthologues:

Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Immune System R-HSA-168256
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Innate Immune System R-HSA-168249
CLEC7A/inflammasome pathway R-HSA-5660668
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Downstream TCR signaling R-HSA-202424
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Immune System R-HSA-168256
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
TCR signaling R-HSA-202403
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of NF-kappaB in B cells R-HSA-1169091
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
C-type lectin receptors (CLRs) R-HSA-5621481
TCR signaling R-HSA-202403
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A/inflammasome pathway R-HSA-5660668
Innate Immune System R-HSA-168249
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A/inflammasome pathway R-HSA-5660668
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Downstream TCR signaling R-HSA-202424
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
Adaptive Immune System R-HSA-1280218
FCERI mediated NF-kB activation R-HSA-2871837
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
CLEC7A/inflammasome pathway R-HSA-5660668
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TCR signaling R-HSA-202403
CLEC7A/inflammasome pathway R-HSA-5660668
Signaling by the B Cell Receptor (BCR) R-HSA-983705
C-type lectin receptors (CLRs) R-HSA-5621481
Activation of NF-kappaB in B cells R-HSA-1169091
Downstream TCR signaling R-HSA-202424
CLEC7A (Dectin-1) signaling R-HSA-5607764
Immune System R-HSA-168256
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Immune System R-HSA-168256
Adaptive Immune System R-HSA-1280218
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CLEC7A (Dectin-1) signaling R-HSA-5607764
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream TCR signaling R-HSA-202424
FCERI mediated NF-kB activation R-HSA-2871837
TCR signaling R-HSA-202403
Activation of NF-kappaB in B cells R-HSA-1169091
CLEC7A (Dectin-1) signaling R-HSA-5607764
Activation of NF-kappaB in B cells R-HSA-1169091
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A/inflammasome pathway R-HSA-5660668
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
TCR signaling R-HSA-202403
Adaptive Immune System R-HSA-1280218
Innate Immune System R-HSA-168249
FCERI mediated NF-kB activation R-HSA-2871837
C-type lectin receptors (CLRs) R-HSA-5621481
Immune System R-HSA-168256
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream TCR signaling R-HSA-202424

Expression Atlas ENSG00000172175
LRG display in Ensembl gene LRG_1221
NCBI gene (formerly Entrezgene) 10892
GeneCards 6819
HGNC Symbol HGNC:6819
MIM gene 604860
MIM morbid 615468
UniProtKB Gene Name Q9UDY8
WikiGene 10892
Gene: GUCY1A2
Ensembl ID : ENSG00000152402
Description: guanylate cyclase 1 soluble subunit alpha 2
Gene Synonyms: GC-SA2,GUC1A2
13 APIs:
203 Possible Orthologues:

Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Smooth Muscle Contraction R-HSA-445355
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Muscle contraction R-HSA-397014
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
Smooth Muscle Contraction R-HSA-445355
Smooth Muscle Contraction R-HSA-445355
Muscle contraction R-HSA-397014
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Platelet homeostasis R-HSA-418346
Smooth Muscle Contraction R-HSA-445355
Hemostasis R-HSA-109582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Muscle contraction R-HSA-397014
Platelet homeostasis R-HSA-418346
Smooth Muscle Contraction R-HSA-445355
Smooth Muscle Contraction R-HSA-445355
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
Muscle contraction R-HSA-397014
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Smooth Muscle Contraction R-HSA-445355
Platelet homeostasis R-HSA-418346
Muscle contraction R-HSA-397014
Hemostasis R-HSA-109582
Smooth Muscle Contraction R-HSA-445355
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Platelet homeostasis R-HSA-418346
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Smooth Muscle Contraction R-HSA-445355
Hemostasis R-HSA-109582
Smooth Muscle Contraction R-HSA-445355
Platelet homeostasis R-HSA-418346
Muscle contraction R-HSA-397014
Nitric oxide stimulates guanylate cyclase R-HSA-392154

Expression Atlas ENSG00000152402
NCBI gene (formerly Entrezgene) 2977
GeneCards 4684
HGNC Symbol HGNC:4684
MIM gene 601244
UniProtKB Gene Name P33402
WikiGene 2977
Gene: ROCK2
Ensembl ID : ENSG00000134318
Description: Rho associated coiled-coil containing protein kinase 2
Gene Synonyms:
11 APIs:
298 Possible Orthologues:

Axon guidance R-HSA-422475
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
RHOH GTPase cycle R-HSA-9013407
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase cycle R-HSA-9012999
RHOBTB1 GTPase cycle R-HSA-9013422
EPHB-mediated forward signaling R-HSA-3928662
Sema4D in semaphorin signaling R-HSA-400685
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
EPHA-mediated growth cone collapse R-HSA-3928663
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Semaphorin interactions R-HSA-373755
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate ROCKs R-HSA-5627117
GPCR downstream signalling R-HSA-388396
RHOH GTPase cycle R-HSA-9013407
Disease R-HSA-1643685
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHB-mediated forward signaling R-HSA-3928662
EPHA-mediated growth cone collapse R-HSA-3928663
SARS-CoV Infections R-HSA-9679506
Nervous system development R-HSA-9675108
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Signal Transduction R-HSA-162582
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Potential therapeutics for SARS R-HSA-9679191
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
RHO GTPase cycle R-HSA-9012999
RHOB GTPase cycle R-HSA-9013026
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
Developmental Biology R-HSA-1266738
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
RHO GTPase cycle R-HSA-9012999
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Potential therapeutics for SARS R-HSA-9679191
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by VEGF R-HSA-194138
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPase Effectors R-HSA-195258
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
Sema4D in semaphorin signaling R-HSA-400685
RHO GTPase Effectors R-HSA-195258
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
RHOBTB1 GTPase cycle R-HSA-9013422
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (12/13) signalling events R-HSA-416482
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
RHO GTPase cycle R-HSA-9012999
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Axon guidance R-HSA-422475
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
RHOH GTPase cycle R-HSA-9013407
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
RHOB GTPase cycle R-HSA-9013026
Developmental Biology R-HSA-1266738
Potential therapeutics for SARS R-HSA-9679191
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Semaphorin interactions R-HSA-373755
RHOBTB1 GTPase cycle R-HSA-9013422
GPCR downstream signalling R-HSA-388396
RHOA GTPase cycle R-HSA-8980692
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPases Activate ROCKs R-HSA-5627117
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHA-mediated growth cone collapse R-HSA-3928663
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Semaphorin interactions R-HSA-373755
Developmental Biology R-HSA-1266738
Signaling by VEGF R-HSA-194138
RHO GTPase cycle R-HSA-9012999
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
G alpha (12/13) signalling events R-HSA-416482
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Sema4D in semaphorin signaling R-HSA-400685
SARS-CoV Infections R-HSA-9679506
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
RHO GTPases Activate ROCKs R-HSA-5627117
RHOBTB GTPase Cycle R-HSA-9706574
GPCR downstream signalling R-HSA-388396
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHO GTPase Effectors R-HSA-195258
RHOH GTPase cycle R-HSA-9013407
Signaling by GPCR R-HSA-372790
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
RHOH GTPase cycle R-HSA-9013407
RHOBTB GTPase Cycle R-HSA-9706574
RHOA GTPase cycle R-HSA-8980692
RHOC GTPase cycle R-HSA-9013106
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
Developmental Biology R-HSA-1266738
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOB GTPase cycle R-HSA-9013026
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Potential therapeutics for SARS R-HSA-9679191
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPases Activate ROCKs R-HSA-5627117
Disease R-HSA-1643685
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
Signal Transduction R-HSA-162582
RHOBTB1 GTPase cycle R-HSA-9013422
RHOH GTPase cycle R-HSA-9013407
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
EPH-Ephrin signaling R-HSA-2682334
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Rho GTPases R-HSA-194315
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
GPCR downstream signalling R-HSA-388396
Sema4D in semaphorin signaling R-HSA-400685
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHOC GTPase cycle R-HSA-9013106
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPases Activate ROCKs R-HSA-5627117
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
G alpha (12/13) signalling events R-HSA-416482
Infectious disease R-HSA-5663205
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Sema4D in semaphorin signaling R-HSA-400685
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
RHO GTPases Activate ROCKs R-HSA-5627117
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by GPCR R-HSA-372790
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOB GTPase cycle R-HSA-9013026
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
G alpha (12/13) signalling events R-HSA-416482
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
Axon guidance R-HSA-422475
EPHB-mediated forward signaling R-HSA-3928662
SARS-CoV Infections R-HSA-9679506
GPCR downstream signalling R-HSA-388396
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPase cycle R-HSA-9012999
RHOA GTPase cycle R-HSA-8980692
GPCR downstream signalling R-HSA-388396
Nervous system development R-HSA-9675108
VEGFA-VEGFR2 Pathway R-HSA-4420097
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
RHOBTB1 GTPase cycle R-HSA-9013422
EPH-Ephrin signaling R-HSA-2682334
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
RHOB GTPase cycle R-HSA-9013026
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOH GTPase cycle R-HSA-9013407
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOC GTPase cycle R-HSA-9013106
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
RHOC GTPase cycle R-HSA-9013106
RHOBTB GTPase Cycle R-HSA-9706574
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
Nervous system development R-HSA-9675108
RHOBTB1 GTPase cycle R-HSA-9013422
RHOA GTPase cycle R-HSA-8980692
G alpha (12/13) signalling events R-HSA-416482
GPCR downstream signalling R-HSA-388396
Signaling by Rho GTPases R-HSA-194315
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Potential therapeutics for SARS R-HSA-9679191
RHO GTPases Activate ROCKs R-HSA-5627117
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Semaphorin interactions R-HSA-373755

Expression Atlas ENSG00000134318
NCBI gene (formerly Entrezgene) 9475
GeneCards 10252
HGNC Symbol HGNC:10252
MIM gene 604002
UniProtKB Gene Name O75116
WikiGene 9475
Gene: BRAF
Ensembl ID : ENSG00000157764
Description: B-Raf proto-oncogene, serine/threonine kinase
Gene Synonyms: BRAF-1,BRAF1
14 APIs:
211 Possible Orthologues:

Oncogenic MAPK signaling R-HSA-6802957
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RAF activation R-HSA-5673000
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by RAS mutants R-HSA-6802949
Oncogenic MAPK signaling R-HSA-6802957
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by FGFR4 R-HSA-5654743
Negative feedback regulation of MAPK pathway R-HSA-5674499
Disease R-HSA-1643685
Negative regulation of MAPK pathway R-HSA-5675221
MAPK family signaling cascades R-HSA-5683057
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by NTRK1 (TRKA) R-HSA-187037
Negative regulation of FGFR1 signaling R-HSA-5654726
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
ARMS-mediated activation R-HSA-170984
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by FGFR3 R-HSA-5654741
Negative regulation of FGFR2 signaling R-HSA-5654727
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by FGFR1 R-HSA-5654736
Frs2-mediated activation R-HSA-170968
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by FGFR R-HSA-190236
Signalling to ERKs R-HSA-187687
RAF/MAP kinase cascade R-HSA-5673001
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAP2K and MAPK activation R-HSA-5674135
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR2 R-HSA-5654738
Signaling by NTRKs R-HSA-166520
Signal Transduction R-HSA-162582
Signaling by RAF1 mutants R-HSA-9656223
RAF/MAP kinase cascade R-HSA-5673001
Prolonged ERK activation events R-HSA-169893
Spry regulation of FGF signaling R-HSA-1295596
Negative regulation of FGFR3 signaling R-HSA-5654732
Negative regulation of MAPK pathway R-HSA-5675221
Disease R-HSA-1643685
MAPK family signaling cascades R-HSA-5683057
Signaling by FGFR2 R-HSA-5654738
Signaling by RAS mutants R-HSA-6802949
RAF activation R-HSA-5673000
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by FGFR1 R-HSA-5654736
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Negative feedback regulation of MAPK pathway R-HSA-5674499
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by NTRK1 (TRKA) R-HSA-187037
Frs2-mediated activation R-HSA-170968
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signalling to p38 via RIT and RIN R-HSA-187706
Signalling to ERKs R-HSA-187687
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by FGFR4 R-HSA-5654743
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by FGFR R-HSA-190236
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR4 signaling R-HSA-5654733
ARMS-mediated activation R-HSA-170984
Negative regulation of FGFR1 signaling R-HSA-5654726
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAP2K and MAPK activation R-HSA-5674135
Signal Transduction R-HSA-162582
Signaling by FGFR3 R-HSA-5654741
Signaling downstream of RAS mutants R-HSA-9649948
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by RAF1 mutants R-HSA-9656223
RAF/MAP kinase cascade R-HSA-5673001
ARMS-mediated activation R-HSA-170984
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR R-HSA-190236
Disease R-HSA-1643685
Frs2-mediated activation R-HSA-170968
RAF activation R-HSA-5673000
Signaling by RAS mutants R-HSA-6802949
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by FGFR4 R-HSA-5654743
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by FGFR3 R-HSA-5654741
Negative feedback regulation of MAPK pathway R-HSA-5674499
MAPK family signaling cascades R-HSA-5683057
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by NTRK1 (TRKA) R-HSA-187037
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR1 R-HSA-5654736
Signaling by NTRKs R-HSA-166520
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Negative regulation of FGFR4 signaling R-HSA-5654733
Prolonged ERK activation events R-HSA-169893
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR2 R-HSA-5654738
Oncogenic MAPK signaling R-HSA-6802957
Signalling to p38 via RIT and RIN R-HSA-187706
Signal Transduction R-HSA-162582
Signalling to ERKs R-HSA-187687
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF activation R-HSA-5673000
Signaling by FGFR2 R-HSA-5654738
Signaling by FGFR4 R-HSA-5654743
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signalling to ERKs R-HSA-187687
ARMS-mediated activation R-HSA-170984
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAF1 mutants R-HSA-9656223
Signaling by NTRKs R-HSA-166520
Signaling by FGFR3 R-HSA-5654741
Oncogenic MAPK signaling R-HSA-6802957
MAPK family signaling cascades R-HSA-5683057
MAP2K and MAPK activation R-HSA-5674135
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of FGFR2 signaling R-HSA-5654727
Frs2-mediated activation R-HSA-170968
Disease R-HSA-1643685
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Spry regulation of FGF signaling R-HSA-1295596
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by FGFR1 R-HSA-5654736
Signal Transduction R-HSA-162582
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Negative regulation of FGFR3 signaling R-HSA-5654732
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by BRAF and RAF1 fusions R-HSA-6802952
RAF/MAP kinase cascade R-HSA-5673001
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling downstream of RAS mutants R-HSA-9649948
Prolonged ERK activation events R-HSA-169893
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by RAS mutants R-HSA-6802949
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR1 signaling R-HSA-5654726
Negative regulation of FGFR2 signaling R-HSA-5654727
Negative regulation of FGFR3 signaling R-HSA-5654732
RAF/MAP kinase cascade R-HSA-5673001
Negative feedback regulation of MAPK pathway R-HSA-5674499
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
ARMS-mediated activation R-HSA-170984
RAF activation R-HSA-5673000
Signaling by FGFR1 R-HSA-5654736
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Spry regulation of FGF signaling R-HSA-1295596
Prolonged ERK activation events R-HSA-169893
Signalling to ERKs R-HSA-187687
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK family signaling cascades R-HSA-5683057
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by RAS mutants R-HSA-6802949
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by NTRKs R-HSA-166520
Signaling by RAF1 mutants R-HSA-9656223
MAP2K and MAPK activation R-HSA-5674135
Signaling downstream of RAS mutants R-HSA-9649948
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR R-HSA-190236
Signaling by NTRK1 (TRKA) R-HSA-187037
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Oncogenic MAPK signaling R-HSA-6802957
Disease R-HSA-1643685
Frs2-mediated activation R-HSA-170968
Signaling by FGFR3 R-HSA-5654741
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by MRAS-complex mutants R-HSA-9660537
Negative regulation of FGFR4 signaling R-HSA-5654733
RAF/MAP kinase cascade R-HSA-5673001
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling by FGFR2 R-HSA-5654738
Signal Transduction R-HSA-162582
Signaling by FGFR1 R-HSA-5654736
Signaling downstream of RAS mutants R-HSA-9649948
Spry regulation of FGF signaling R-HSA-1295596
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of FGFR4 signaling R-HSA-5654733
ARMS-mediated activation R-HSA-170984
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by RAS mutants R-HSA-6802949
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Disease R-HSA-1643685
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
MAP2K and MAPK activation R-HSA-5674135
Signalling to p38 via RIT and RIN R-HSA-187706
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR3 R-HSA-5654741
Oncogenic MAPK signaling R-HSA-6802957
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative regulation of FGFR1 signaling R-HSA-5654726
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR R-HSA-190236
Signaling by NTRK1 (TRKA) R-HSA-187037
Negative regulation of FGFR3 signaling R-HSA-5654732
Negative feedback regulation of MAPK pathway R-HSA-5674499
Frs2-mediated activation R-HSA-170968
Signaling by FGFR4 R-HSA-5654743
Signaling by MRAS-complex mutants R-HSA-9660537
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by NTRKs R-HSA-166520
Signalling to ERKs R-HSA-187687
MAPK family signaling cascades R-HSA-5683057
RAF activation R-HSA-5673000
Signaling by RAF1 mutants R-HSA-9656223
Oncogenic MAPK signaling R-HSA-6802957
Signalling to ERKs R-HSA-187687
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR4 signaling R-HSA-5654733
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by FGFR1 R-HSA-5654736
ARMS-mediated activation R-HSA-170984
Negative regulation of MAPK pathway R-HSA-5675221
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by FGFR R-HSA-190236
Signaling by FGFR3 R-HSA-5654741
Negative regulation of FGFR3 signaling R-HSA-5654732
Frs2-mediated activation R-HSA-170968
Signal Transduction R-HSA-162582
Signaling by FGFR4 R-HSA-5654743
Disease R-HSA-1643685
Signaling by FGFR2 R-HSA-5654738
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR1 signaling R-HSA-5654726
RAF activation R-HSA-5673000
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of FGFR2 signaling R-HSA-5654727
RAF/MAP kinase cascade R-HSA-5673001
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling downstream of RAS mutants R-HSA-9649948
MAP2K and MAPK activation R-HSA-5674135
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Spry regulation of FGF signaling R-HSA-1295596
Signaling by NTRK1 (TRKA) R-HSA-187037
Prolonged ERK activation events R-HSA-169893
Signaling by RAS mutants R-HSA-6802949
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by MRAS-complex mutants R-HSA-9660537
Signaling by RAF1 mutants R-HSA-9656223
MAPK family signaling cascades R-HSA-5683057
RAF activation R-HSA-5673000
Negative regulation of MAPK pathway R-HSA-5675221
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Negative regulation of FGFR1 signaling R-HSA-5654726
Oncogenic MAPK signaling R-HSA-6802957
Signaling by NTRK1 (TRKA) R-HSA-187037
MAPK family signaling cascades R-HSA-5683057
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Signaling by FGFR3 R-HSA-5654741
Signaling by RAF1 mutants R-HSA-9656223
Signaling by NTRKs R-HSA-166520
Signalling to p38 via RIT and RIN R-HSA-187706
Prolonged ERK activation events R-HSA-169893
Signalling to ERKs R-HSA-187687
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling downstream of RAS mutants R-HSA-9649948
Frs2-mediated activation R-HSA-170968
RAF/MAP kinase cascade R-HSA-5673001
Signaling by BRAF and RAF1 fusions R-HSA-6802952
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signaling by FGFR2 R-HSA-5654738
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signaling by MRAS-complex mutants R-HSA-9660537
ARMS-mediated activation R-HSA-170984
Negative regulation of FGFR4 signaling R-HSA-5654733
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by RAS mutants R-HSA-6802949
Signal Transduction R-HSA-162582
Signaling by FGFR4 R-HSA-5654743
Disease R-HSA-1643685
Signaling by FGFR1 R-HSA-5654736
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR R-HSA-190236
Negative regulation of FGFR3 signaling R-HSA-5654732
Spry regulation of FGF signaling R-HSA-1295596
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by RAF1 mutants R-HSA-9656223
Signaling by FGFR R-HSA-190236
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
ARMS-mediated activation R-HSA-170984
MAPK1/MAPK3 signaling R-HSA-5684996
Negative regulation of FGFR2 signaling R-HSA-5654727
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
MAPK family signaling cascades R-HSA-5683057
Signaling by NTRKs R-HSA-166520
Negative regulation of FGFR4 signaling R-HSA-5654733
Signaling by RAS mutants R-HSA-6802949
Signaling by FGFR2 R-HSA-5654738
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
Frs2-mediated activation R-HSA-170968
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by FGFR3 R-HSA-5654741
Disease R-HSA-1643685
Signaling downstream of RAS mutants R-HSA-9649948
Signaling by NTRK1 (TRKA) R-HSA-187037
RAF activation R-HSA-5673000
Negative feedback regulation of MAPK pathway R-HSA-5674499
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Signalling to ERKs R-HSA-187687
Negative regulation of FGFR3 signaling R-HSA-5654732
MAP2K and MAPK activation R-HSA-5674135
Signaling by FGFR1 R-HSA-5654736
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946
Signaling by MRAS-complex mutants R-HSA-9660537
Oncogenic MAPK signaling R-HSA-6802957
Negative regulation of MAPK pathway R-HSA-5675221
RAF/MAP kinase cascade R-HSA-5673001
Spry regulation of FGF signaling R-HSA-1295596
Signaling by BRAF and RAF1 fusions R-HSA-6802952
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Signal Transduction R-HSA-162582
Negative regulation of FGFR1 signaling R-HSA-5654726
Prolonged ERK activation events R-HSA-169893
Signaling by FGFR4 R-HSA-5654743
Disease R-HSA-1643685
Signaling by RAS mutants R-HSA-6802949
Signaling by FGFR4 R-HSA-5654743
Signalling to p38 via RIT and RIN R-HSA-187706
Signaling by FGFR2 R-HSA-5654738
Spry regulation of FGF signaling R-HSA-1295596
Signaling by FGFR1 R-HSA-5654736
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
RAF/MAP kinase cascade R-HSA-5673001
Signaling by RAF1 mutants R-HSA-9656223
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by high-kinase activity BRAF mutants R-HSA-6802948
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Prolonged ERK activation events R-HSA-169893
MAPK family signaling cascades R-HSA-5683057
Negative regulation of FGFR2 signaling R-HSA-5654727
Signaling by FGFR R-HSA-190236
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840
Negative regulation of MAPK pathway R-HSA-5675221
ARMS-mediated activation R-HSA-170984
Signalling to ERKs R-HSA-187687
Signaling by MRAS-complex mutants R-HSA-9660537
Signal Transduction R-HSA-162582
Signaling by FGFR3 R-HSA-5654741
Signaling downstream of RAS mutants R-HSA-9649948
RAF activation R-HSA-5673000
Negative feedback regulation of MAPK pathway R-HSA-5674499
Signaling by NTRKs R-HSA-166520
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955
Negative regulation of FGFR3 signaling R-HSA-5654732
Frs2-mediated activation R-HSA-170968
Negative regulation of FGFR4 signaling R-HSA-5654733
Negative regulation of FGFR1 signaling R-HSA-5654726
Signaling by BRAF and RAF1 fusions R-HSA-6802952
MAP2K and MAPK activation R-HSA-5674135
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946

Expression Atlas ENSG00000157764
LRG display in Ensembl gene LRG_299
NCBI gene (formerly Entrezgene) 673
GeneCards 1097
HGNC Symbol HGNC:1097
MIM gene 164757
MIM morbid 613707
UniProtKB Gene Name P15056
WikiGene 673
Gene: ERBB4
Ensembl ID : ENSG00000178568
Description: erb-b2 receptor tyrosine kinase 4
Gene Synonyms: ALS19,HER4
12 APIs:
320 Possible Orthologues:

Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
SHC1 events in ERBB2 signaling R-HSA-1250196
Disease R-HSA-1643685
PIP3 activates AKT signaling R-HSA-1257604
Downregulation of ERBB4 signaling R-HSA-1253288
Downregulation of ERBB2 signaling R-HSA-8863795
MAPK1/MAPK3 signaling R-HSA-5684996
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Nuclear Receptors R-HSA-9006931
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by ERBB2 R-HSA-1227986
Estrogen-dependent gene expression R-HSA-9018519
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Neuronal System R-HSA-112316
MAPK family signaling cascades R-HSA-5683057
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by ERBB2 KD Mutants R-HSA-9664565
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Post NMDA receptor activation events R-HSA-438064
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PI3K/AKT Signaling in Cancer R-HSA-2219528
Transmission across Chemical Synapses R-HSA-112315
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
SHC1 events in ERBB4 signaling R-HSA-1250347
PI3K events in ERBB2 signaling R-HSA-1963642
Long-term potentiation R-HSA-9620244
ESR-mediated signaling R-HSA-8939211
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB4 R-HSA-1236394
Signaling by ERBB2 in Cancer R-HSA-1227990
Activation of NMDA receptors and postsynaptic events R-HSA-442755
PI3K/AKT Signaling in Cancer R-HSA-2219528
MAPK family signaling cascades R-HSA-5683057
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by PTK6 R-HSA-8848021
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Nuclear Receptors R-HSA-9006931
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Transmission across Chemical Synapses R-HSA-112315
Downregulation of ERBB2 signaling R-HSA-8863795
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB2 R-HSA-1227986
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PIP3 activates AKT signaling R-HSA-1257604
ERBB2 Regulates Cell Motility R-HSA-6785631
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by ERBB2 in Cancer R-HSA-1227990
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SHC1 events in ERBB2 signaling R-HSA-1250196
RAF/MAP kinase cascade R-HSA-5673001
ESR-mediated signaling R-HSA-8939211
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Post NMDA receptor activation events R-HSA-438064
Signaling by ERBB4 R-HSA-1236394
Nuclear signaling by ERBB4 R-HSA-1251985
MAPK1/MAPK3 signaling R-HSA-5684996
Long-term potentiation R-HSA-9620244
Intracellular signaling by second messengers R-HSA-9006925
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB2 KD Mutants R-HSA-9664565
Downregulation of ERBB4 signaling R-HSA-1253288
Estrogen-dependent gene expression R-HSA-9018519
PI3K events in ERBB2 signaling R-HSA-1963642
Neuronal System R-HSA-112316
SHC1 events in ERBB4 signaling R-HSA-1250347
Disease R-HSA-1643685
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
MAPK1/MAPK3 signaling R-HSA-5684996
Nuclear signaling by ERBB4 R-HSA-1251985
Intracellular signaling by second messengers R-HSA-9006925
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PI3K events in ERBB2 signaling R-HSA-1963642
Post NMDA receptor activation events R-HSA-438064
RAF/MAP kinase cascade R-HSA-5673001
ERBB2 Regulates Cell Motility R-HSA-6785631
ESR-mediated signaling R-HSA-8939211
MAPK family signaling cascades R-HSA-5683057
Transmission across Chemical Synapses R-HSA-112315
Signaling by ERBB2 in Cancer R-HSA-1227990
Long-term potentiation R-HSA-9620244
PI3K/AKT Signaling in Cancer R-HSA-2219528
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by PTK6 R-HSA-8848021
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Estrogen-dependent gene expression R-HSA-9018519
SHC1 events in ERBB4 signaling R-HSA-1250347
Signaling by ERBB2 R-HSA-1227986
Downregulation of ERBB4 signaling R-HSA-1253288
PI3K events in ERBB4 signaling R-HSA-1250342
Neuronal System R-HSA-112316
ERBB2 Activates PTK6 Signaling R-HSA-8847993
SHC1 events in ERBB2 signaling R-HSA-1250196
Downregulation of ERBB2 signaling R-HSA-8863795
Disease R-HSA-1643685
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Negative regulation of the PI3K/AKT network R-HSA-199418
Activation of NMDA receptors and postsynaptic events R-HSA-442755
PIP3 activates AKT signaling R-HSA-1257604
Signaling by ERBB4 R-HSA-1236394
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ERBB2 KD Mutants R-HSA-9664565
SHC1 events in ERBB4 signaling R-HSA-1250347
Signaling by ERBB2 in Cancer R-HSA-1227990
Downregulation of ERBB2 signaling R-HSA-8863795
SHC1 events in ERBB2 signaling R-HSA-1250196
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by Nuclear Receptors R-HSA-9006931
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by ERBB4 R-HSA-1236394
Disease R-HSA-1643685
Transmission across Chemical Synapses R-HSA-112315
ESR-mediated signaling R-HSA-8939211
Nuclear signaling by ERBB4 R-HSA-1251985
Intracellular signaling by second messengers R-HSA-9006925
GRB2 events in ERBB2 signaling R-HSA-1963640
MAPK family signaling cascades R-HSA-5683057
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Downregulation of ERBB4 signaling R-HSA-1253288
Signaling by ERBB2 KD Mutants R-HSA-9664565
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K events in ERBB2 signaling R-HSA-1963642
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by PTK6 R-HSA-8848021
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Signaling by ERBB2 R-HSA-1227986
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Estrogen-dependent gene expression R-HSA-9018519
Long-term potentiation R-HSA-9620244
Signal Transduction R-HSA-162582
PI3K events in ERBB4 signaling R-HSA-1250342
MAPK1/MAPK3 signaling R-HSA-5684996
Neuronal System R-HSA-112316
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Post NMDA receptor activation events R-HSA-438064
Activation of NMDA receptors and postsynaptic events R-HSA-442755
PI3K/AKT Signaling in Cancer R-HSA-2219528
PIP3 activates AKT signaling R-HSA-1257604
Neuronal System R-HSA-112316
Downregulation of ERBB2 signaling R-HSA-8863795
Signaling by Nuclear Receptors R-HSA-9006931
Intracellular signaling by second messengers R-HSA-9006925
SHC1 events in ERBB2 signaling R-HSA-1250196
Post NMDA receptor activation events R-HSA-438064
Estrogen-dependent gene expression R-HSA-9018519
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Negative regulation of the PI3K/AKT network R-HSA-199418
PI3K events in ERBB4 signaling R-HSA-1250342
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
MAPK family signaling cascades R-HSA-5683057
Signaling by ERBB4 R-HSA-1236394
Signaling by ERBB2 R-HSA-1227986
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Nuclear signaling by ERBB4 R-HSA-1251985
Downregulation of ERBB4 signaling R-HSA-1253288
Signaling by PTK6 R-HSA-8848021
RAF/MAP kinase cascade R-HSA-5673001
PI3K events in ERBB2 signaling R-HSA-1963642
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Disease R-HSA-1643685
GRB2 events in ERBB2 signaling R-HSA-1963640
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 in Cancer R-HSA-1227990
Transmission across Chemical Synapses R-HSA-112315
Long-term potentiation R-HSA-9620244
ESR-mediated signaling R-HSA-8939211
PI3K/AKT Signaling in Cancer R-HSA-2219528
SHC1 events in ERBB4 signaling R-HSA-1250347
ERBB2 Regulates Cell Motility R-HSA-6785631
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
MAPK1/MAPK3 signaling R-HSA-5684996
Downregulation of ERBB2 signaling R-HSA-8863795
SHC1 events in ERBB2 signaling R-HSA-1250196
ERBB2 Regulates Cell Motility R-HSA-6785631
Estrogen-dependent gene expression R-HSA-9018519
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
PI3K events in ERBB2 signaling R-HSA-1963642
Long-term potentiation R-HSA-9620244
Neuronal System R-HSA-112316
Signaling by ERBB2 in Cancer R-HSA-1227990
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Downregulation of ERBB4 signaling R-HSA-1253288
Signaling by Nuclear Receptors R-HSA-9006931
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Negative regulation of the PI3K/AKT network R-HSA-199418
RAF/MAP kinase cascade R-HSA-5673001
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB4 R-HSA-1236394
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
MAPK family signaling cascades R-HSA-5683057
ESR-mediated signaling R-HSA-8939211
MAPK1/MAPK3 signaling R-HSA-5684996
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Intracellular signaling by second messengers R-HSA-9006925
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ERBB2 R-HSA-1227986
SHC1 events in ERBB4 signaling R-HSA-1250347
PI3K events in ERBB4 signaling R-HSA-1250342
Post NMDA receptor activation events R-HSA-438064
Signal Transduction R-HSA-162582
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Signaling by PTK6 R-HSA-8848021
Transmission across Chemical Synapses R-HSA-112315
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
PIP3 activates AKT signaling R-HSA-1257604
Long-term potentiation R-HSA-9620244
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Downregulation of ERBB2 signaling R-HSA-8863795
SHC1 events in ERBB2 signaling R-HSA-1250196
Post NMDA receptor activation events R-HSA-438064
MAPK family signaling cascades R-HSA-5683057
Signaling by Nuclear Receptors R-HSA-9006931
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Nuclear signaling by ERBB4 R-HSA-1251985
PI3K events in ERBB4 signaling R-HSA-1250342
Signal Transduction R-HSA-162582
PI3K events in ERBB2 signaling R-HSA-1963642
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 in Cancer R-HSA-1227990
PI3K/AKT Signaling in Cancer R-HSA-2219528
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by ERBB4 R-HSA-1236394
Estrogen-dependent gene expression R-HSA-9018519
MAPK1/MAPK3 signaling R-HSA-5684996
Transmission across Chemical Synapses R-HSA-112315
Neuronal System R-HSA-112316
ESR-mediated signaling R-HSA-8939211
Activation of NMDA receptors and postsynaptic events R-HSA-442755
GRB2 events in ERBB2 signaling R-HSA-1963640
Negative regulation of the PI3K/AKT network R-HSA-199418
Intracellular signaling by second messengers R-HSA-9006925
Downregulation of ERBB4 signaling R-HSA-1253288
Signaling by ERBB2 R-HSA-1227986
SHC1 events in ERBB4 signaling R-HSA-1250347
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by PTK6 R-HSA-8848021
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Nuclear signaling by ERBB4 R-HSA-1251985
Signaling by PTK6 R-HSA-8848021
Signaling by Nuclear Receptors R-HSA-9006931
ESR-mediated signaling R-HSA-8939211
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by ERBB2 KD Mutants R-HSA-9664565
Post NMDA receptor activation events R-HSA-438064
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
PI3K events in ERBB4 signaling R-HSA-1250342
Disease R-HSA-1643685
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Downregulation of ERBB2 signaling R-HSA-8863795
Transmission across Chemical Synapses R-HSA-112315
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
SHC1 events in ERBB4 signaling R-HSA-1250347
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
RAF/MAP kinase cascade R-HSA-5673001
MAPK family signaling cascades R-HSA-5683057
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
MAPK1/MAPK3 signaling R-HSA-5684996
Long-term potentiation R-HSA-9620244
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Signaling by ERBB2 in Cancer R-HSA-1227990
SHC1 events in ERBB2 signaling R-HSA-1250196
Estrogen-dependent gene expression R-HSA-9018519
Negative regulation of the PI3K/AKT network R-HSA-199418
GRB2 events in ERBB2 signaling R-HSA-1963640
Activation of NMDA receptors and postsynaptic events R-HSA-442755
ERBB2 Regulates Cell Motility R-HSA-6785631
Neuronal System R-HSA-112316
Intracellular signaling by second messengers R-HSA-9006925
Downregulation of ERBB4 signaling R-HSA-1253288
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
Signaling by ERBB4 R-HSA-1236394
Long-term potentiation R-HSA-9620244
Signaling by PTK6 R-HSA-8848021
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Estrogen-dependent gene expression R-HSA-9018519
Signaling by Nuclear Receptors R-HSA-9006931
SHC1 events in ERBB2 signaling R-HSA-1250196
GRB2 events in ERBB2 signaling R-HSA-1963640
Signaling by ERBB4 R-HSA-1236394
ESR-mediated signaling R-HSA-8939211
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downregulation of ERBB4 signaling R-HSA-1253288
MAPK1/MAPK3 signaling R-HSA-5684996
Downregulation of ERBB2 signaling R-HSA-8863795
ERBB2 Regulates Cell Motility R-HSA-6785631
Signaling by ERBB2 KD Mutants R-HSA-9664565
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Transmission across Chemical Synapses R-HSA-112315
Nuclear signaling by ERBB4 R-HSA-1251985
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
MAPK family signaling cascades R-HSA-5683057
SHC1 events in ERBB4 signaling R-HSA-1250347
Post NMDA receptor activation events R-HSA-438064
Neuronal System R-HSA-112316
Negative regulation of the PI3K/AKT network R-HSA-199418
Signal Transduction R-HSA-162582
Signaling by ERBB2 in Cancer R-HSA-1227990
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Disease R-HSA-1643685
Signaling by ERBB2 R-HSA-1227986
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
PI3K events in ERBB4 signaling R-HSA-1250342
RAF/MAP kinase cascade R-HSA-5673001
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
ERBB2 Activates PTK6 Signaling R-HSA-8847993
Intracellular signaling by second messengers R-HSA-9006925
Estrogen-dependent gene expression R-HSA-9018519
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signal Transduction R-HSA-162582
Signaling by ERBB2 R-HSA-1227986
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by Nuclear Receptors R-HSA-9006931
MAPK family signaling cascades R-HSA-5683057
Signaling by ERBB2 in Cancer R-HSA-1227990
Disease R-HSA-1643685
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by PTK6 R-HSA-8848021
Transmission across Chemical Synapses R-HSA-112315
PI3K/AKT Signaling in Cancer R-HSA-2219528
Long-term potentiation R-HSA-9620244
ERBB2 Activates PTK6 Signaling R-HSA-8847993
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
ERBB2 Regulates Cell Motility R-HSA-6785631
Downregulation of ERBB2 signaling R-HSA-8863795
GRB2 events in ERBB2 signaling R-HSA-1963640
Activation of NMDA receptors and postsynaptic events R-HSA-442755
Post NMDA receptor activation events R-HSA-438064
SHC1 events in ERBB2 signaling R-HSA-1250196
Nuclear signaling by ERBB4 R-HSA-1251985
ESR-mediated signaling R-HSA-8939211
Signaling by ERBB4 R-HSA-1236394
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Neuronal System R-HSA-112316
SHC1 events in ERBB4 signaling R-HSA-1250347
MAPK1/MAPK3 signaling R-HSA-5684996
Downregulation of ERBB4 signaling R-HSA-1253288

Expression Atlas ENSG00000178568
NCBI gene (formerly Entrezgene) 2066
GeneCards 3432
HGNC Symbol HGNC:3432
MIM gene 600543
MIM morbid 615515
UniProtKB Gene Name Q15303
WikiGene 2066
Gene: NT5E
Ensembl ID : ENSG00000135318
Description: 5'-nucleotidase ecto
Gene Synonyms: CALJA,CD73,EN,ENT,NT5
1 APIs:
250 Possible Orthologues:

Nucleotide catabolism R-HSA-8956319
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Infectious disease R-HSA-5663205
Metabolism of vitamins and cofactors R-HSA-196854
Purine catabolism R-HSA-74259
Nicotinate metabolism R-HSA-196807
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Metabolism of vitamins and cofactors R-HSA-196854
Nicotinate metabolism R-HSA-196807
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Infectious disease R-HSA-5663205
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Metabolism of nucleotides R-HSA-15869
Purine catabolism R-HSA-74259
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Metabolism of vitamins and cofactors R-HSA-196854
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Pyrimidine catabolism R-HSA-73621
Leishmania infection R-HSA-9658195
Infectious disease R-HSA-5663205
Metabolism of nucleotides R-HSA-15869
Metabolism of vitamins and cofactors R-HSA-196854
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Metabolism R-HSA-1430728
Nicotinate metabolism R-HSA-196807
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nucleotide catabolism R-HSA-8956319
Disease R-HSA-1643685
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Metabolism of vitamins and cofactors R-HSA-196854
Pyrimidine catabolism R-HSA-73621
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Leishmania infection R-HSA-9658195
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Disease R-HSA-1643685
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Metabolism R-HSA-1430728
Nucleotide catabolism R-HSA-8956319
Infectious disease R-HSA-5663205
Nicotinate metabolism R-HSA-196807
Metabolism of vitamins and cofactors R-HSA-196854
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Metabolism of vitamins and cofactors R-HSA-196854
Infectious disease R-HSA-5663205
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Purine catabolism R-HSA-74259
Pyrimidine catabolism R-HSA-73621
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Metabolism of vitamins and cofactors R-HSA-196854
Metabolism of nucleotides R-HSA-15869
Purine catabolism R-HSA-74259
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide catabolism R-HSA-8956319
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Pyrimidine catabolism R-HSA-73621
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Purine catabolism R-HSA-74259
Leishmania infection R-HSA-9658195
Metabolism of vitamins and cofactors R-HSA-196854
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Disease R-HSA-1643685
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Nicotinate metabolism R-HSA-196807
Metabolism R-HSA-1430728
Pyrimidine catabolism R-HSA-73621
Infectious disease R-HSA-5663205
Purine catabolism R-HSA-74259
Metabolism of vitamins and cofactors R-HSA-196854
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nicotinate metabolism R-HSA-196807
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Leishmania infection R-HSA-9658195
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Metabolism of nucleotides R-HSA-15869
Disease R-HSA-1643685
Nucleotide catabolism R-HSA-8956319
Metabolism of vitamins and cofactors R-HSA-196854
Nicotinate metabolism R-HSA-196807
Nucleotide catabolism R-HSA-8956319
Infectious disease R-HSA-5663205
Purine catabolism R-HSA-74259
Metabolism of water-soluble vitamins and cofactors R-HSA-196849
Pyrimidine catabolism R-HSA-73621
Metabolism of nucleotides R-HSA-15869
Metabolism R-HSA-1430728
Disease R-HSA-1643685
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Leishmania infection R-HSA-9658195

Expression Atlas ENSG00000135318
NCBI gene (formerly Entrezgene) 4907
GeneCards 8021
HGNC Symbol HGNC:8021
MIM gene 129190
MIM morbid 211800
UniProtKB Gene Name Q96B60
WikiGene 4907