Gene: GBA1
Ensembl ID : ENSG00000177628
Description: glucosylceramidase beta 1
Gene Synonyms: GBA,GLUC
1 APIs:
245 Possible Orthologues:

Metabolism of proteins R-HSA-392499
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Glycosphingolipid metabolism R-HSA-1660662
Protein folding R-HSA-391251
Sphingolipid metabolism R-HSA-428157
Chaperonin-mediated protein folding R-HSA-390466
Protein folding R-HSA-391251
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Metabolism of proteins R-HSA-392499
Sphingolipid metabolism R-HSA-428157
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Glycosphingolipid metabolism R-HSA-1660662
Chaperonin-mediated protein folding R-HSA-390466
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of lipids R-HSA-556833
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Sphingolipid metabolism R-HSA-428157
Glycosphingolipid metabolism R-HSA-1660662
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Protein folding R-HSA-391251
Metabolism of lipids R-HSA-556833
Glycosphingolipid metabolism R-HSA-1660662
Protein folding R-HSA-391251
Sphingolipid metabolism R-HSA-428157
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of proteins R-HSA-392499
Metabolism R-HSA-1430728
Glycosphingolipid metabolism R-HSA-1660662
Metabolism R-HSA-1430728
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Protein folding R-HSA-391251
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of lipids R-HSA-556833
Sphingolipid metabolism R-HSA-428157
Metabolism of proteins R-HSA-392499
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of lipids R-HSA-556833
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Metabolism R-HSA-1430728
Glycosphingolipid metabolism R-HSA-1660662
Metabolism of proteins R-HSA-392499
Sphingolipid metabolism R-HSA-428157
Protein folding R-HSA-391251
Metabolism of proteins R-HSA-392499
Metabolism R-HSA-1430728
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of lipids R-HSA-556833
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Sphingolipid metabolism R-HSA-428157
Glycosphingolipid metabolism R-HSA-1660662
Protein folding R-HSA-391251
Protein folding R-HSA-391251
Metabolism R-HSA-1430728
Glycosphingolipid metabolism R-HSA-1660662
Sphingolipid metabolism R-HSA-428157
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Metabolism of lipids R-HSA-556833
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of proteins R-HSA-392499
Metabolism of lipids R-HSA-556833
Protein folding R-HSA-391251
Metabolism of proteins R-HSA-392499
Chaperonin-mediated protein folding R-HSA-390466
Sphingolipid metabolism R-HSA-428157
Glycosphingolipid metabolism R-HSA-1660662
Metabolism R-HSA-1430728
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Metabolism of proteins R-HSA-392499
Chaperonin-mediated protein folding R-HSA-390466
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Metabolism R-HSA-1430728
Sphingolipid metabolism R-HSA-428157
Metabolism of lipids R-HSA-556833
Glycosphingolipid metabolism R-HSA-1660662
Protein folding R-HSA-391251
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of lipids R-HSA-556833
Metabolism of proteins R-HSA-392499
Protein folding R-HSA-391251
Metabolism R-HSA-1430728
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Glycosphingolipid metabolism R-HSA-1660662
Sphingolipid metabolism R-HSA-428157

Expression Atlas ENSG00000177628
NCBI gene (formerly Entrezgene) 2629
GeneCards 4177
HGNC Symbol HGNC:4177
MIM gene 606463
MIM morbid 608013
UniProtKB Gene Name P04062
WikiGene 2629
Gene: CDC7
Ensembl ID : ENSG00000097046
Description: cell division cycle 7
Gene Synonyms: CDC7L1,HSCDC7,HSK1,HUCDC7
4 APIs:
209 Possible Orthologues:

DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Activation of ATR in response to replication stress R-HSA-176187
Transcriptional Regulation by E2F6 R-HSA-8953750
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle, Mitotic R-HSA-69278
Transcriptional Regulation by E2F6 R-HSA-8953750
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
Transcriptional Regulation by E2F6 R-HSA-8953750
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Mitotic G1 phase and G1/S transition R-HSA-453279
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional Regulation by E2F6 R-HSA-8953750
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Cell Cycle R-HSA-1640170
Transcriptional Regulation by E2F6 R-HSA-8953750
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Activation of the pre-replicative complex R-HSA-68962
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
Activation of ATR in response to replication stress R-HSA-176187
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Transcriptional Regulation by E2F6 R-HSA-8953750
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
Activation of ATR in response to replication stress R-HSA-176187
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by E2F6 R-HSA-8953750
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by E2F6 R-HSA-8953750
Activation of ATR in response to replication stress R-HSA-176187
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Activation of ATR in response to replication stress R-HSA-176187
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional Regulation by E2F6 R-HSA-8953750
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by E2F6 R-HSA-8953750
Activation of the pre-replicative complex R-HSA-68962
G1/S Transition R-HSA-69206
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
Activation of ATR in response to replication stress R-HSA-176187
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Transcriptional Regulation by E2F6 R-HSA-8953750
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Activation of the pre-replicative complex R-HSA-68962
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160

Expression Atlas ENSG00000097046
NCBI gene (formerly Entrezgene) 8317
GeneCards 1745
HGNC Symbol HGNC:1745
MIM gene 603311
UniProtKB Gene Name O00311
WikiGene 8317
Gene: PNP
Ensembl ID : ENSG00000198805
Description: purine nucleoside phosphorylase
Gene Synonyms: NP,PUNP
1 APIs:
123 Possible Orthologues:

Purine salvage R-HSA-74217
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Neutrophil degranulation R-HSA-6798695
Nucleotide catabolism defects R-HSA-9735786
Innate Immune System R-HSA-168249
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Diseases of nucleotide metabolism R-HSA-9735804
Ribavirin ADME R-HSA-9755088
Drug ADME R-HSA-9748784
Immune System R-HSA-168256
Disease R-HSA-1643685
Diseases of metabolism R-HSA-5668914
Nucleotide salvage R-HSA-8956321
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Disease R-HSA-1643685
Metabolism R-HSA-1430728
Innate Immune System R-HSA-168249
Metabolism of nucleotides R-HSA-15869
Diseases of nucleotide metabolism R-HSA-9735804
Drug ADME R-HSA-9748784
Purine catabolism R-HSA-74259
Ribavirin ADME R-HSA-9755088
Neutrophil degranulation R-HSA-6798695
Nucleotide catabolism defects R-HSA-9735786
Immune System R-HSA-168256
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Diseases of metabolism R-HSA-5668914
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Purine salvage R-HSA-74217
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Metabolism R-HSA-1430728
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Disease R-HSA-1643685
Nucleotide catabolism R-HSA-8956319
Nucleotide catabolism defects R-HSA-9735786
Purine catabolism R-HSA-74259
Diseases of metabolism R-HSA-5668914
Innate Immune System R-HSA-168249
Metabolism of nucleotides R-HSA-15869
Purine salvage R-HSA-74217
Nucleotide salvage R-HSA-8956321
Drug ADME R-HSA-9748784
Diseases of nucleotide metabolism R-HSA-9735804
Ribavirin ADME R-HSA-9755088
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism defects R-HSA-9735786
Drug ADME R-HSA-9748784
Innate Immune System R-HSA-168249
Metabolism R-HSA-1430728
Diseases of nucleotide metabolism R-HSA-9735804
Immune System R-HSA-168256
Ribavirin ADME R-HSA-9755088
Purine catabolism R-HSA-74259
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Nucleotide catabolism R-HSA-8956319
Neutrophil degranulation R-HSA-6798695
Nucleotide salvage R-HSA-8956321
Diseases of metabolism R-HSA-5668914
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Disease R-HSA-1643685
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Ribavirin ADME R-HSA-9755088
Metabolism of nucleotides R-HSA-15869
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321
Innate Immune System R-HSA-168249
Diseases of metabolism R-HSA-5668914
Purine salvage R-HSA-74217
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Purine catabolism R-HSA-74259
Diseases of nucleotide metabolism R-HSA-9735804
Metabolism R-HSA-1430728
Drug ADME R-HSA-9748784
Innate Immune System R-HSA-168249
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Ribavirin ADME R-HSA-9755088
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Immune System R-HSA-168256
Diseases of nucleotide metabolism R-HSA-9735804
Disease R-HSA-1643685
Nucleotide salvage R-HSA-8956321
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Drug ADME R-HSA-9748784
Diseases of metabolism R-HSA-5668914
Neutrophil degranulation R-HSA-6798695
Disease R-HSA-1643685
Metabolism of nucleotides R-HSA-15869
Nucleotide salvage R-HSA-8956321
Purine catabolism R-HSA-74259
Metabolism R-HSA-1430728
Drug ADME R-HSA-9748784
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Diseases of metabolism R-HSA-5668914
Ribavirin ADME R-HSA-9755088
Innate Immune System R-HSA-168249
Nucleotide catabolism defects R-HSA-9735786
Purine salvage R-HSA-74217
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Diseases of nucleotide metabolism R-HSA-9735804
Nucleotide catabolism R-HSA-8956319
Metabolism of nucleotides R-HSA-15869
Neutrophil degranulation R-HSA-6798695
Immune System R-HSA-168256
Purine salvage R-HSA-74217
Nucleotide catabolism defects R-HSA-9735786
Ribavirin ADME R-HSA-9755088
Metabolism R-HSA-1430728
Purine catabolism R-HSA-74259
Innate Immune System R-HSA-168249
Disease R-HSA-1643685
Drug ADME R-HSA-9748784
Diseases of nucleotide metabolism R-HSA-9735804
Diseases of metabolism R-HSA-5668914
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763
Nucleotide catabolism R-HSA-8956319
Nucleotide salvage R-HSA-8956321

Expression Atlas ENSG00000198805
LRG display in Ensembl gene LRG_91
NCBI gene (formerly Entrezgene) 4860
GeneCards 7892
HGNC Symbol HGNC:7892
MIM gene 164050
MIM morbid 613179
UniProtKB Gene Name V9HWH6
WikiGene 4860
Gene: NPM1
Ensembl ID : ENSG00000181163
Description: nucleophosmin 1
Gene Synonyms: B23,NPM
2 APIs:
158 Possible Orthologues:

Chromosome Maintenance R-HSA-73886
SARS-CoV-1 Infection R-HSA-9678108
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Nucleosome assembly R-HSA-774815
Interactions of Rev with host cellular proteins R-HSA-177243
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
ALK mutants bind TKIs R-HSA-9700645
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle R-HSA-1640170
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Disease R-HSA-1643685
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SARS-CoV-1-host interactions R-HSA-9692914
HIV Infection R-HSA-162906
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Host Interactions of HIV factors R-HSA-162909
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
SUMOylation of transcription cofactors R-HSA-3899300
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
Gene expression (Transcription) R-HSA-74160
SARS-CoV Infections R-HSA-9679506
Nuclear import of Rev protein R-HSA-180746
RNA Polymerase II Transcription R-HSA-73857
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
SARS-CoV-1-host interactions R-HSA-9692914
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cell Cycle R-HSA-1640170
Interactions of Rev with host cellular proteins R-HSA-177243
HIV Infection R-HSA-162906
SARS-CoV-1 Infection R-HSA-9678108
Chromosome Maintenance R-HSA-73886
Nucleosome assembly R-HSA-774815
Nuclear import of Rev protein R-HSA-180746
SUMOylation of transcription cofactors R-HSA-3899300
Disease R-HSA-1643685
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Generic Transcription Pathway R-HSA-212436
Signaling by ALK in cancer R-HSA-9700206
Host Interactions of HIV factors R-HSA-162909
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Transcriptional Regulation by TP53 R-HSA-3700989
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Infectious disease R-HSA-5663205
Metabolism of proteins R-HSA-392499
ALK mutants bind TKIs R-HSA-9700645
SARS-CoV Infections R-HSA-9679506
Gene expression (Transcription) R-HSA-74160
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
SUMOylation of transcription cofactors R-HSA-3899300
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Generic Transcription Pathway R-HSA-212436
SARS-CoV Infections R-HSA-9679506
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Signaling by ALK in cancer R-HSA-9700206
Host Interactions of HIV factors R-HSA-162909
Post-translational protein modification R-HSA-597592
Chromosome Maintenance R-HSA-73886
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
RNA Polymerase II Transcription R-HSA-73857
HIV Infection R-HSA-162906
SUMOylation R-HSA-2990846
SARS-CoV-1 Infection R-HSA-9678108
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
Nucleosome assembly R-HSA-774815
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Signaling by ALK fusions and activated point mutants R-HSA-9725370
SARS-CoV-1-host interactions R-HSA-9692914
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Cell Cycle R-HSA-1640170
ALK mutants bind TKIs R-HSA-9700645
Nuclear import of Rev protein R-HSA-180746
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Transcriptional Regulation by TP53 R-HSA-3700989
Interactions of Rev with host cellular proteins R-HSA-177243
Cell Cycle R-HSA-1640170
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interactions of Rev with host cellular proteins R-HSA-177243
Host Interactions of HIV factors R-HSA-162909
SARS-CoV-1 Infection R-HSA-9678108
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
Signaling by ALK in cancer R-HSA-9700206
Metabolism of proteins R-HSA-392499
Nuclear import of Rev protein R-HSA-180746
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Nucleosome assembly R-HSA-774815
Generic Transcription Pathway R-HSA-212436
ALK mutants bind TKIs R-HSA-9700645
Post-translational protein modification R-HSA-597592
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Disease R-HSA-1643685
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Infectious disease R-HSA-5663205
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
SUMOylation R-HSA-2990846
SUMOylation of transcription cofactors R-HSA-3899300
Chromosome Maintenance R-HSA-73886
Gene expression (Transcription) R-HSA-74160
SARS-CoV-1-host interactions R-HSA-9692914
SARS-CoV Infections R-HSA-9679506
Transcriptional Regulation by TP53 R-HSA-3700989
HIV Infection R-HSA-162906
SARS-CoV-1-host interactions R-HSA-9692914
Generic Transcription Pathway R-HSA-212436
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interactions of Rev with host cellular proteins R-HSA-177243
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
Cell Cycle R-HSA-1640170
Signaling by ALK in cancer R-HSA-9700206
ALK mutants bind TKIs R-HSA-9700645
SUMOylation of transcription cofactors R-HSA-3899300
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Chromosome Maintenance R-HSA-73886
Nuclear import of Rev protein R-HSA-180746
SARS-CoV-1 Infection R-HSA-9678108
HIV Infection R-HSA-162906
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371
Transcriptional Regulation by TP53 R-HSA-3700989
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
SARS-CoV Infections R-HSA-9679506
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279
Nucleosome assembly R-HSA-774815

Expression Atlas ENSG00000181163
LRG display in Ensembl gene LRG_458
NCBI gene (formerly Entrezgene) 4869
GeneCards 7910
HGNC Symbol HGNC:7910
MIM gene 164040
MIM morbid 601626
UniProtKB Gene Name P06748
WikiGene 4869
Gene: CASP8
Ensembl ID : ENSG00000064012
Description: caspase 8
Gene Synonyms: CASP-8,FLICE,MACH,MCH5
1 APIs:
132 Possible Orthologues:

CLEC7A/inflammasome pathway R-HSA-5660668
Diseases of programmed cell death R-HSA-9645723
NOD1/2 Signaling Pathway R-HSA-168638
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of necroptotic cell death R-HSA-5675482
TRAIL signaling R-HSA-75158
Programmed Cell Death R-HSA-5357801
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signal Transduction R-HSA-162582
MyD88 cascade initiated on plasma membrane R-HSA-975871
Death Receptor Signaling R-HSA-73887
TRIF-mediated programmed cell death R-HSA-2562578
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TNF signaling R-HSA-75893
FasL/ CD95L signaling R-HSA-75157
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Regulated Necrosis R-HSA-5218859
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signaling by Interleukins R-HSA-449147
Toll-like Receptor Cascades R-HSA-168898
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of TNFR1 signaling R-HSA-5357905
CASP8 activity is inhibited R-HSA-5218900
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TNFR1-induced proapoptotic signaling R-HSA-5357786
Dimerization of procaspase-8 R-HSA-69416
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
MyD88 dependent cascade initiated on endosome R-HSA-975155
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 family signaling R-HSA-446652
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation by c-FLIP R-HSA-3371378
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Regulation of TNFR1 signaling R-HSA-5357905
Diseases of programmed cell death R-HSA-9645723
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CASP8 activity is inhibited R-HSA-5218900
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Immune System R-HSA-168256
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptotic execution phase R-HSA-75153
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 family signaling R-HSA-446652
Apoptotic cleavage of cellular proteins R-HSA-111465
NOD1/2 Signaling Pathway R-HSA-168638
Signal Transduction R-HSA-162582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 signaling R-HSA-9020702
TNFR1-induced proapoptotic signaling R-HSA-5357786
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulated Necrosis R-HSA-5218859
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Regulation of necroptotic cell death R-HSA-5675482
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
RIPK1-mediated regulated necrosis R-HSA-5213460
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TNF signaling R-HSA-75893
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAIL signaling R-HSA-75158
Intrinsic Pathway for Apoptosis R-HSA-109606
Programmed Cell Death R-HSA-5357801
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Dimerization of procaspase-8 R-HSA-69416
Disease R-HSA-1643685
FasL/ CD95L signaling R-HSA-75157
TNFR1-induced proapoptotic signaling R-HSA-5357786
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TNF signaling R-HSA-75893
CLEC7A (Dectin-1) signaling R-HSA-5607764
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Regulation by c-FLIP R-HSA-3371378
Immune System R-HSA-168256
Diseases of programmed cell death R-HSA-9645723
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
Programmed Cell Death R-HSA-5357801
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
CLEC7A/inflammasome pathway R-HSA-5660668
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAIL signaling R-HSA-75158
Regulated Necrosis R-HSA-5218859
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Apoptotic cleavage of cellular proteins R-HSA-111465
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of necroptotic cell death R-HSA-5675482
NOD1/2 Signaling Pathway R-HSA-168638
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRIF-mediated programmed cell death R-HSA-2562578
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Apoptotic cleavage of cellular proteins R-HSA-111465
TNFR1-induced proapoptotic signaling R-HSA-5357786
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation by c-FLIP R-HSA-3371378
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
C-type lectin receptors (CLRs) R-HSA-5621481
TRAIL signaling R-HSA-75158
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TNF signaling R-HSA-75893
Interleukin-1 family signaling R-HSA-446652
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Death Receptor Signaling R-HSA-73887
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic execution phase R-HSA-75153
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 cascade initiated on plasma membrane R-HSA-975871
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll-like Receptor Cascades R-HSA-168898
Dimerization of procaspase-8 R-HSA-69416
NOD1/2 Signaling Pathway R-HSA-168638
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Regulation of NF-kappa B signaling R-HSA-9758274
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulated Necrosis R-HSA-5218859
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of necroptotic cell death R-HSA-5675482
MyD88-independent TLR4 cascade R-HSA-166166
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
CLEC7A/inflammasome pathway R-HSA-5660668
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNFR1-induced proapoptotic signaling R-HSA-5357786
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88 dependent cascade initiated on endosome R-HSA-975155
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic cleavage of cellular proteins R-HSA-111465
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NOD1/2 Signaling Pathway R-HSA-168638
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
CLEC7A/inflammasome pathway R-HSA-5660668
MyD88-independent TLR4 cascade R-HSA-166166
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
CASP8 activity is inhibited R-HSA-5218900
Apoptotic execution phase R-HSA-75153
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Innate Immune System R-HSA-168249
Regulation of necroptotic cell death R-HSA-5675482
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Dimerization of procaspase-8 R-HSA-69416
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
FasL/ CD95L signaling R-HSA-75157
TRAIL signaling R-HSA-75158
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF-mediated programmed cell death R-HSA-2562578
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases of programmed cell death R-HSA-9645723
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
CLEC7A/inflammasome pathway R-HSA-5660668
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRIF-mediated programmed cell death R-HSA-2562578
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88-independent TLR4 cascade R-HSA-166166
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Regulation by c-FLIP R-HSA-3371378
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNF signaling R-HSA-75893
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88 dependent cascade initiated on endosome R-HSA-975155
Disease R-HSA-1643685
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptosis R-HSA-109581
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll-like Receptor Cascades R-HSA-168898
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of necroptotic cell death R-HSA-5675482
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic execution phase R-HSA-75153
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAIL signaling R-HSA-75158
FasL/ CD95L signaling R-HSA-75157
CASP8 activity is inhibited R-HSA-5218900
Innate Immune System R-HSA-168249
Dimerization of procaspase-8 R-HSA-69416
Death Receptor Signaling R-HSA-73887
Interleukin-1 signaling R-HSA-9020702
Diseases of programmed cell death R-HSA-9645723
Immune System R-HSA-168256
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cytokine Signaling in Immune system R-HSA-1280215
Apoptotic cleavage of cellular proteins R-HSA-111465
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88-independent TLR4 cascade R-HSA-166166
Regulation by c-FLIP R-HSA-3371378
Regulated Necrosis R-HSA-5218859
FasL/ CD95L signaling R-HSA-75157
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of NF-kappa B signaling R-HSA-9758274
Diseases of programmed cell death R-HSA-9645723
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Immune System R-HSA-168256
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Apoptosis R-HSA-109581
Regulation of necroptotic cell death R-HSA-5675482
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Apoptotic execution phase R-HSA-75153
NOD1/2 Signaling Pathway R-HSA-168638
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CLEC7A/inflammasome pathway R-HSA-5660668
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRAIL signaling R-HSA-75158
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
Dimerization of procaspase-8 R-HSA-69416
TRIF-mediated programmed cell death R-HSA-2562578
C-type lectin receptors (CLRs) R-HSA-5621481
Toll-like Receptor Cascades R-HSA-168898
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAIL signaling R-HSA-75158
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RIPK1-mediated regulated necrosis R-HSA-5213460
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Disease R-HSA-1643685
Regulated Necrosis R-HSA-5218859
TNFR1-induced proapoptotic signaling R-HSA-5357786
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Apoptotic execution phase R-HSA-75153
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Dimerization of procaspase-8 R-HSA-69416
Regulation of necroptotic cell death R-HSA-5675482
Regulation of TNFR1 signaling R-HSA-5357905
Interleukin-1 signaling R-HSA-9020702
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
C-type lectin receptors (CLRs) R-HSA-5621481
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
Intrinsic Pathway for Apoptosis R-HSA-109606
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 family signaling R-HSA-446652
TRIF-mediated programmed cell death R-HSA-2562578
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Programmed Cell Death R-HSA-5357801
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulated Necrosis R-HSA-5218859
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TNFR1 signaling R-HSA-5357905
Disease R-HSA-1643685
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRIF-mediated programmed cell death R-HSA-2562578
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Regulation of NF-kappa B signaling R-HSA-9758274
CASP8 activity is inhibited R-HSA-5218900
NOD1/2 Signaling Pathway R-HSA-168638
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation by c-FLIP R-HSA-3371378
TRAIL signaling R-HSA-75158
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 cascade initiated on plasma membrane R-HSA-975871
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by Interleukins R-HSA-449147
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Apoptotic execution phase R-HSA-75153
RIPK1-mediated regulated necrosis R-HSA-5213460
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Apoptosis R-HSA-109581
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Regulation of necroptotic cell death R-HSA-5675482
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 signaling R-HSA-9020702
CLEC7A/inflammasome pathway R-HSA-5660668
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of programmed cell death R-HSA-9645723
TNFR1-induced proapoptotic signaling R-HSA-5357786
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation by c-FLIP R-HSA-3371378
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Dimerization of procaspase-8 R-HSA-69416
Diseases of programmed cell death R-HSA-9645723
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
C-type lectin receptors (CLRs) R-HSA-5621481
Regulated Necrosis R-HSA-5218859
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
RIPK1-mediated regulated necrosis R-HSA-5213460
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Apoptotic execution phase R-HSA-75153
Cytokine Signaling in Immune system R-HSA-1280215
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAIL signaling R-HSA-75158
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Immune System R-HSA-168256
CASP8 activity is inhibited R-HSA-5218900
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
FasL/ CD95L signaling R-HSA-75157
CLEC7A/inflammasome pathway R-HSA-5660668
TNFR1-induced proapoptotic signaling R-HSA-5357786
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF-mediated programmed cell death R-HSA-2562578
TNF signaling R-HSA-75893
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Regulation of NF-kappa B signaling R-HSA-9758274
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
MyD88-independent TLR4 cascade R-HSA-166166
Regulation of necroptotic cell death R-HSA-5675482
Apoptosis R-HSA-109581
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061

Expression Atlas ENSG00000064012
LRG display in Ensembl gene LRG_34
NCBI gene (formerly Entrezgene) 841
GeneCards 1509
HGNC Symbol HGNC:1509
MIM gene 601763
MIM morbid 607271
UniProtKB Gene Name Q14790
WikiGene 841
Gene: KLKB1
Ensembl ID : ENSG00000164344
Description: kallikrein B1
Gene Synonyms: KLK3
6 APIs:
209 Possible Orthologues:

Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Diseases of hemostasis R-HSA-9671793
Degradation of the extracellular matrix R-HSA-1474228
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor XII causes hereditary angioedema R-HSA-9657688
Hemostasis R-HSA-109582
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Extracellular matrix organization R-HSA-1474244
Activation of Matrix Metalloproteinases R-HSA-1592389
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Extracellular matrix organization R-HSA-1474244
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Disease R-HSA-1643685
Degradation of the extracellular matrix R-HSA-1474228
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Activation of Matrix Metalloproteinases R-HSA-1592389
Activation of Matrix Metalloproteinases R-HSA-1592389
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective factor XII causes hereditary angioedema R-HSA-9657688
Degradation of the extracellular matrix R-HSA-1474228
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective factor XII causes hereditary angioedema R-HSA-9657688
Disease R-HSA-1643685
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Hemostasis R-HSA-109582
Activation of Matrix Metalloproteinases R-HSA-1592389
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Diseases of hemostasis R-HSA-9671793
Degradation of the extracellular matrix R-HSA-1474228
Extracellular matrix organization R-HSA-1474244
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Hemostasis R-HSA-109582
Diseases of hemostasis R-HSA-9671793
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Defective factor XII causes hereditary angioedema R-HSA-9657688
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Activation of Matrix Metalloproteinases R-HSA-1592389
Extracellular matrix organization R-HSA-1474244
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Degradation of the extracellular matrix R-HSA-1474228
Degradation of the extracellular matrix R-HSA-1474228
Diseases of hemostasis R-HSA-9671793
Hemostasis R-HSA-109582
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877
Defective SERPING1 causes hereditary angioedema R-HSA-9657689
Disease R-HSA-1643685
Extracellular matrix organization R-HSA-1474244
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496
Activation of Matrix Metalloproteinases R-HSA-1592389
Defective factor XII causes hereditary angioedema R-HSA-9657688

Expression Atlas ENSG00000164344
LRG display in Ensembl gene LRG_565
NCBI gene (formerly Entrezgene) 3818
GeneCards 6371
HGNC Symbol HGNC:6371
MIM gene 229000
MIM morbid 612423
UniProtKB Gene Name E9PBC5
WikiGene 3818
Gene: NOS2
Ensembl ID : ENSG00000007171
Description: nitric oxide synthase 2
Gene Synonyms: HEP-NOS,INOS,NOS,NOS2A
2 APIs:
166 Possible Orthologues:

Response of Mtb to phagocytosis R-HSA-9637690
Peroxisomal protein import R-HSA-9033241
Disease R-HSA-1643685
Infection with Mycobacterium tuberculosis R-HSA-9635486
Hemostasis R-HSA-109582
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Immune System R-HSA-168256
Response of Mtb to phagocytosis R-HSA-9637690
Suppression of phagosomal maturation R-HSA-9637687
Innate Immune System R-HSA-168249
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Protein localization R-HSA-9609507
Inhibition of nitric oxide production R-HSA-9636249
Infectious disease R-HSA-5663205
Platelet homeostasis R-HSA-418346
Cytokine Signaling in Immune system R-HSA-1280215
ROS and RNS production in phagocytes R-HSA-1222556
Signaling by Interleukins R-HSA-449147
ROS and RNS production in phagocytes R-HSA-1222556
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Response of Mtb to phagocytosis R-HSA-9637690
Immune System R-HSA-168256
Infection with Mycobacterium tuberculosis R-HSA-9635486
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Platelet homeostasis R-HSA-418346
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Hemostasis R-HSA-109582
Inhibition of nitric oxide production R-HSA-9636249
Peroxisomal protein import R-HSA-9033241
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Suppression of phagosomal maturation R-HSA-9637687
Protein localization R-HSA-9609507
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
ROS and RNS production in phagocytes R-HSA-1222556
Peroxisomal protein import R-HSA-9033241
Suppression of phagosomal maturation R-HSA-9637687
Cytokine Signaling in Immune system R-HSA-1280215
Protein localization R-HSA-9609507
Innate Immune System R-HSA-168249
Platelet homeostasis R-HSA-418346
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Hemostasis R-HSA-109582
Infection with Mycobacterium tuberculosis R-HSA-9635486
Response of Mtb to phagocytosis R-HSA-9637690
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Inhibition of nitric oxide production R-HSA-9636249
Immune System R-HSA-168256
Disease R-HSA-1643685
Platelet homeostasis R-HSA-418346
Peroxisomal protein import R-HSA-9033241
Infection with Mycobacterium tuberculosis R-HSA-9635486
Inhibition of nitric oxide production R-HSA-9636249
Protein localization R-HSA-9609507
Signaling by Interleukins R-HSA-449147
Suppression of phagosomal maturation R-HSA-9637687
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Cytokine Signaling in Immune system R-HSA-1280215
Innate Immune System R-HSA-168249
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
ROS and RNS production in phagocytes R-HSA-1222556
Peroxisomal protein import R-HSA-9033241
Infection with Mycobacterium tuberculosis R-HSA-9635486
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Suppression of phagosomal maturation R-HSA-9637687
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
Inhibition of nitric oxide production R-HSA-9636249
ROS and RNS production in phagocytes R-HSA-1222556
Platelet homeostasis R-HSA-418346
Response of Mtb to phagocytosis R-HSA-9637690
Disease R-HSA-1643685
Hemostasis R-HSA-109582
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Protein localization R-HSA-9609507
Immune System R-HSA-168256
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Suppression of phagosomal maturation R-HSA-9637687
Infectious disease R-HSA-5663205
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
Disease R-HSA-1643685
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Peroxisomal protein import R-HSA-9033241
Inhibition of nitric oxide production R-HSA-9636249
ROS and RNS production in phagocytes R-HSA-1222556
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Protein localization R-HSA-9609507
Innate Immune System R-HSA-168249
Infection with Mycobacterium tuberculosis R-HSA-9635486
Response of Mtb to phagocytosis R-HSA-9637690
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Response of Mtb to phagocytosis R-HSA-9637690
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
ROS and RNS production in phagocytes R-HSA-1222556
Infection with Mycobacterium tuberculosis R-HSA-9635486
Cytokine Signaling in Immune system R-HSA-1280215
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Peroxisomal protein import R-HSA-9033241
Platelet homeostasis R-HSA-418346
Hemostasis R-HSA-109582
Signaling by Interleukins R-HSA-449147
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Protein localization R-HSA-9609507
Inhibition of nitric oxide production R-HSA-9636249
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Suppression of phagosomal maturation R-HSA-9637687
ROS and RNS production in phagocytes R-HSA-1222556
Inhibition of nitric oxide production R-HSA-9636249
Infection with Mycobacterium tuberculosis R-HSA-9635486
Protein localization R-HSA-9609507
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Suppression of phagosomal maturation R-HSA-9637687
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
Innate Immune System R-HSA-168249
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Disease R-HSA-1643685
Response of Mtb to phagocytosis R-HSA-9637690
Cytokine Signaling in Immune system R-HSA-1280215
Platelet homeostasis R-HSA-418346
Signaling by Interleukins R-HSA-449147
Peroxisomal protein import R-HSA-9033241
Immune System R-HSA-168256
Infection with Mycobacterium tuberculosis R-HSA-9635486
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Protein localization R-HSA-9609507
Nitric oxide stimulates guanylate cyclase R-HSA-392154
Suppression of phagosomal maturation R-HSA-9637687
Inhibition of nitric oxide production R-HSA-9636249
Signaling by Interleukins R-HSA-449147
Platelet homeostasis R-HSA-418346
Disease R-HSA-1643685
Peroxisomal protein import R-HSA-9033241
Innate Immune System R-HSA-168249
ROS and RNS production in phagocytes R-HSA-1222556
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Infectious disease R-HSA-5663205
Cytokine Signaling in Immune system R-HSA-1280215
Response of Mtb to phagocytosis R-HSA-9637690
Protein localization R-HSA-9609507
Response of Mtb to phagocytosis R-HSA-9637690
Inhibition of nitric oxide production R-HSA-9636249
Infectious disease R-HSA-5663205
Infection with Mycobacterium tuberculosis R-HSA-9635486
Nitric oxide stimulates guanylate cyclase R-HSA-392154
ROS and RNS production in phagocytes R-HSA-1222556
Signaling by Interleukins R-HSA-449147
Peroxisomal protein import R-HSA-9033241
Platelet homeostasis R-HSA-418346
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Suppression of phagosomal maturation R-HSA-9637687
Disease R-HSA-1643685
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Hemostasis R-HSA-109582
Cytokine Signaling in Immune system R-HSA-1280215

Expression Atlas ENSG00000007171
NCBI gene (formerly Entrezgene) 4843
GeneCards 7873
HGNC Symbol HGNC:7873
MIM gene 163730
MIM morbid 611162
UniProtKB Gene Name P35228
WikiGene 4843
Gene: ROCK2
Ensembl ID : ENSG00000134318
Description: Rho associated coiled-coil containing protein kinase 2
Gene Synonyms:
11 APIs:
298 Possible Orthologues:

Axon guidance R-HSA-422475
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
RHOH GTPase cycle R-HSA-9013407
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase cycle R-HSA-9012999
RHOBTB1 GTPase cycle R-HSA-9013422
EPHB-mediated forward signaling R-HSA-3928662
Sema4D in semaphorin signaling R-HSA-400685
Disease R-HSA-1643685
Signaling by VEGF R-HSA-194138
EPHA-mediated growth cone collapse R-HSA-3928663
Developmental Biology R-HSA-1266738
Nervous system development R-HSA-9675108
Semaphorin interactions R-HSA-373755
Signal Transduction R-HSA-162582
Signaling by GPCR R-HSA-372790
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPases Activate ROCKs R-HSA-5627117
GPCR downstream signalling R-HSA-388396
RHOH GTPase cycle R-HSA-9013407
Disease R-HSA-1643685
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPase Effectors R-HSA-195258
Signaling by Rho GTPases R-HSA-194315
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHB-mediated forward signaling R-HSA-3928662
EPHA-mediated growth cone collapse R-HSA-3928663
SARS-CoV Infections R-HSA-9679506
Nervous system development R-HSA-9675108
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Signal Transduction R-HSA-162582
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Potential therapeutics for SARS R-HSA-9679191
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
RHO GTPase cycle R-HSA-9012999
RHOB GTPase cycle R-HSA-9013026
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
EPH-Ephrin signaling R-HSA-2682334
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
Developmental Biology R-HSA-1266738
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Disease R-HSA-1643685
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
RHO GTPase cycle R-HSA-9012999
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Signaling by GPCR R-HSA-372790
GPCR downstream signalling R-HSA-388396
Potential therapeutics for SARS R-HSA-9679191
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOBTB GTPase Cycle R-HSA-9706574
Signaling by VEGF R-HSA-194138
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPase Effectors R-HSA-195258
Infectious disease R-HSA-5663205
RHOB GTPase cycle R-HSA-9013026
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
Sema4D in semaphorin signaling R-HSA-400685
RHO GTPase Effectors R-HSA-195258
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
RHOBTB1 GTPase cycle R-HSA-9013422
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
G alpha (12/13) signalling events R-HSA-416482
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
RHO GTPase cycle R-HSA-9012999
GPCR downstream signalling R-HSA-388396
RHOC GTPase cycle R-HSA-9013106
Signaling by GPCR R-HSA-372790
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPHB-mediated forward signaling R-HSA-3928662
Potential therapeutics for SARS R-HSA-9679191
Infectious disease R-HSA-5663205
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Disease R-HSA-1643685
Axon guidance R-HSA-422475
RHO GTPases Activate ROCKs R-HSA-5627117
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Axon guidance R-HSA-422475
RHO GTPase cycle R-HSA-9012999
Signaling by Rho GTPases R-HSA-194315
RHOH GTPase cycle R-HSA-9013407
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
EPH-Ephrin signaling R-HSA-2682334
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
SARS-CoV Infections R-HSA-9679506
RHOB GTPase cycle R-HSA-9013026
Developmental Biology R-HSA-1266738
Potential therapeutics for SARS R-HSA-9679191
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Semaphorin interactions R-HSA-373755
RHOBTB1 GTPase cycle R-HSA-9013422
GPCR downstream signalling R-HSA-388396
RHOA GTPase cycle R-HSA-8980692
RHOBTB GTPase Cycle R-HSA-9706574
RHO GTPases Activate ROCKs R-HSA-5627117
VEGFA-VEGFR2 Pathway R-HSA-4420097
EPHA-mediated growth cone collapse R-HSA-3928663
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Semaphorin interactions R-HSA-373755
Developmental Biology R-HSA-1266738
Signaling by VEGF R-HSA-194138
RHO GTPase cycle R-HSA-9012999
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
G alpha (12/13) signalling events R-HSA-416482
RHOA GTPase cycle R-HSA-8980692
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Axon guidance R-HSA-422475
Sema4D in semaphorin signaling R-HSA-400685
SARS-CoV Infections R-HSA-9679506
EPHB-mediated forward signaling R-HSA-3928662
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signal Transduction R-HSA-162582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by Rho GTPases R-HSA-194315
RHOC GTPase cycle R-HSA-9013106
RHO GTPases Activate ROCKs R-HSA-5627117
RHOBTB GTPase Cycle R-HSA-9706574
GPCR downstream signalling R-HSA-388396
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHO GTPase Effectors R-HSA-195258
RHOH GTPase cycle R-HSA-9013407
Signaling by GPCR R-HSA-372790
Nervous system development R-HSA-9675108
Signaling by VEGF R-HSA-194138
RHOH GTPase cycle R-HSA-9013407
RHOBTB GTPase Cycle R-HSA-9706574
RHOA GTPase cycle R-HSA-8980692
RHOC GTPase cycle R-HSA-9013106
Semaphorin interactions R-HSA-373755
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
Developmental Biology R-HSA-1266738
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
RHOB GTPase cycle R-HSA-9013026
Nervous system development R-HSA-9675108
GPCR downstream signalling R-HSA-388396
SARS-CoV Infections R-HSA-9679506
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
G alpha (12/13) signalling events R-HSA-416482
Sema4D in semaphorin signaling R-HSA-400685
Potential therapeutics for SARS R-HSA-9679191
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOBTB1 GTPase cycle R-HSA-9013422
RHO GTPases Activate ROCKs R-HSA-5627117
Disease R-HSA-1643685
EPHA-mediated growth cone collapse R-HSA-3928663
RHOB GTPase cycle R-HSA-9013026
Signal Transduction R-HSA-162582
RHOBTB1 GTPase cycle R-HSA-9013422
RHOH GTPase cycle R-HSA-9013407
Semaphorin interactions R-HSA-373755
Signaling by GPCR R-HSA-372790
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
EPH-Ephrin signaling R-HSA-2682334
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Rho GTPases R-HSA-194315
RHOBTB GTPase Cycle R-HSA-9706574
Developmental Biology R-HSA-1266738
GPCR downstream signalling R-HSA-388396
Sema4D in semaphorin signaling R-HSA-400685
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOA GTPase cycle R-HSA-8980692
SARS-CoV Infections R-HSA-9679506
RHOC GTPase cycle R-HSA-9013106
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPases Activate ROCKs R-HSA-5627117
Potential therapeutics for SARS R-HSA-9679191
Disease R-HSA-1643685
G alpha (12/13) signalling events R-HSA-416482
Infectious disease R-HSA-5663205
RHO GTPase cycle R-HSA-9012999
Axon guidance R-HSA-422475
EPHA-mediated growth cone collapse R-HSA-3928663
Nervous system development R-HSA-9675108
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Sema4D in semaphorin signaling R-HSA-400685
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases R-HSA-194315
RHO GTPases Activate ROCKs R-HSA-5627117
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by GPCR R-HSA-372790
Disease R-HSA-1643685
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOB GTPase cycle R-HSA-9013026
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
G alpha (12/13) signalling events R-HSA-416482
RHOBTB1 GTPase cycle R-HSA-9013422
Infectious disease R-HSA-5663205
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
VEGFA-VEGFR2 Pathway R-HSA-4420097
RHOC GTPase cycle R-HSA-9013106
RHOA GTPase cycle R-HSA-8980692
Nervous system development R-HSA-9675108
EPHA-mediated growth cone collapse R-HSA-3928663
Semaphorin interactions R-HSA-373755
RHO GTPase Effectors R-HSA-195258
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
RHOH GTPase cycle R-HSA-9013407
Axon guidance R-HSA-422475
EPHB-mediated forward signaling R-HSA-3928662
SARS-CoV Infections R-HSA-9679506
GPCR downstream signalling R-HSA-388396
EPH-Ephrin signaling R-HSA-2682334
Signaling by VEGF R-HSA-194138
Signal Transduction R-HSA-162582
Signaling by Rho GTPases R-HSA-194315
EPHA-mediated growth cone collapse R-HSA-3928663
RHO GTPases Activate ROCKs R-HSA-5627117
Axon guidance R-HSA-422475
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
EPHB-mediated forward signaling R-HSA-3928662
RHO GTPase cycle R-HSA-9012999
RHOA GTPase cycle R-HSA-8980692
GPCR downstream signalling R-HSA-388396
Nervous system development R-HSA-9675108
VEGFA-VEGFR2 Pathway R-HSA-4420097
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Developmental Biology R-HSA-1266738
Disease R-HSA-1643685
RHOBTB1 GTPase cycle R-HSA-9013422
EPH-Ephrin signaling R-HSA-2682334
RHO GTPase Effectors R-HSA-195258
Signaling by GPCR R-HSA-372790
RHOB GTPase cycle R-HSA-9013026
Potential therapeutics for SARS R-HSA-9679191
RHOBTB GTPase Cycle R-HSA-9706574
RHOH GTPase cycle R-HSA-9013407
SARS-CoV Infections R-HSA-9679506
Semaphorin interactions R-HSA-373755
RHOC GTPase cycle R-HSA-9013106
Sema4D in semaphorin signaling R-HSA-400685
Infectious disease R-HSA-5663205
G alpha (12/13) signalling events R-HSA-416482
RHO GTPase Effectors R-HSA-195258
SARS-CoV Infections R-HSA-9679506
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
RHOB GTPase cycle R-HSA-9013026
Signaling by VEGF R-HSA-194138
RHOC GTPase cycle R-HSA-9013106
RHOBTB GTPase Cycle R-HSA-9706574
EPHB-mediated forward signaling R-HSA-3928662
RHOH GTPase cycle R-HSA-9013407
Nervous system development R-HSA-9675108
RHOBTB1 GTPase cycle R-HSA-9013422
RHOA GTPase cycle R-HSA-8980692
G alpha (12/13) signalling events R-HSA-416482
GPCR downstream signalling R-HSA-388396
Signaling by Rho GTPases R-HSA-194315
VEGFA-VEGFR2 Pathway R-HSA-4420097
Axon guidance R-HSA-422475
Potential therapeutics for SARS R-HSA-9679191
RHO GTPases Activate ROCKs R-HSA-5627117
EPHA-mediated growth cone collapse R-HSA-3928663
Signaling by GPCR R-HSA-372790
Sema4D in semaphorin signaling R-HSA-400685
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
RHO GTPase cycle R-HSA-9012999
Sema4D induced cell migration and growth-cone collapse R-HSA-416572
EPH-Ephrin signaling R-HSA-2682334
Infectious disease R-HSA-5663205
Disease R-HSA-1643685
Semaphorin interactions R-HSA-373755

Expression Atlas ENSG00000134318
NCBI gene (formerly Entrezgene) 9475
GeneCards 10252
HGNC Symbol HGNC:10252
MIM gene 604002
UniProtKB Gene Name O75116
WikiGene 9475