Gene: NR1H4
Ensembl ID : ENSG00000012504
Description: nuclear receptor subfamily 1 group H member 4
Gene Synonyms: FXR,HRR-1,HRR1,RIP14
9 APIs:
388 Possible Orthologues:

Phase I - Functionalization of compounds R-HSA-211945
Recycling of bile acids and salts R-HSA-159418
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Cytochrome P450 - arranged by substrate type R-HSA-211897
SUMOylation R-HSA-2990846
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Endogenous sterols R-HSA-211976
SUMOylation of intracellular receptors R-HSA-4090294
Metabolism of proteins R-HSA-392499
PPARA activates gene expression R-HSA-1989781
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts R-HSA-192105
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism of lipids R-HSA-556833
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Metabolism of steroids R-HSA-8957322
Bile acid and bile salt metabolism R-HSA-194068
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
Metabolism of lipids R-HSA-556833
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Bile acid and bile salt metabolism R-HSA-194068
Phase I - Functionalization of compounds R-HSA-211945
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Biological oxidations R-HSA-211859
Synthesis of bile acids and bile salts R-HSA-192105
Recycling of bile acids and salts R-HSA-159418
SUMOylation of intracellular receptors R-HSA-4090294
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Generic Transcription Pathway R-HSA-212436
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
Metabolism of lipids R-HSA-556833
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
SUMOylation of intracellular receptors R-HSA-4090294
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of proteins R-HSA-392499
Bile acid and bile salt metabolism R-HSA-194068
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Endogenous sterols R-HSA-211976
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
Biological oxidations R-HSA-211859
Metabolism of steroids R-HSA-8957322
Cytochrome P450 - arranged by substrate type R-HSA-211897
RNA Polymerase II Transcription R-HSA-73857
Recycling of bile acids and salts R-HSA-159418
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Regulation of lipid metabolism by PPARalpha R-HSA-400206
SUMOylation R-HSA-2990846
Synthesis of bile acids and bile salts R-HSA-192105
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
SUMOylation of intracellular receptors R-HSA-4090294
RNA Polymerase II Transcription R-HSA-73857
PPARA activates gene expression R-HSA-1989781
Phase I - Functionalization of compounds R-HSA-211945
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Recycling of bile acids and salts R-HSA-159418
Cytochrome P450 - arranged by substrate type R-HSA-211897
Bile acid and bile salt metabolism R-HSA-194068
Endogenous sterols R-HSA-211976
Metabolism R-HSA-1430728
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism of steroids R-HSA-8957322
Gene expression (Transcription) R-HSA-74160
Metabolism of lipids R-HSA-556833
Biological oxidations R-HSA-211859
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Endogenous sterols R-HSA-211976
Recycling of bile acids and salts R-HSA-159418
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
Cytochrome P450 - arranged by substrate type R-HSA-211897
Synthesis of bile acids and bile salts R-HSA-192105
Biological oxidations R-HSA-211859
Bile acid and bile salt metabolism R-HSA-194068
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
PPARA activates gene expression R-HSA-1989781
Metabolism of steroids R-HSA-8957322
SUMOylation of intracellular receptors R-HSA-4090294
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
SUMOylation of intracellular receptors R-HSA-4090294
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Bile acid and bile salt metabolism R-HSA-194068
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
Metabolism of lipids R-HSA-556833
SUMOylation R-HSA-2990846
Synthesis of bile acids and bile salts R-HSA-192105
PPARA activates gene expression R-HSA-1989781
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Endogenous sterols R-HSA-211976
Recycling of bile acids and salts R-HSA-159418
Bile acid and bile salt metabolism R-HSA-194068
Endogenous sterols R-HSA-211976
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Recycling of bile acids and salts R-HSA-159418
Synthesis of bile acids and bile salts R-HSA-192105
Gene expression (Transcription) R-HSA-74160
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Metabolism of steroids R-HSA-8957322
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
Biological oxidations R-HSA-211859
PPARA activates gene expression R-HSA-1989781
Metabolism of proteins R-HSA-392499
Cytochrome P450 - arranged by substrate type R-HSA-211897
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Phase I - Functionalization of compounds R-HSA-211945
SUMOylation of intracellular receptors R-HSA-4090294
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
Metabolism of lipids R-HSA-556833
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
SUMOylation of intracellular receptors R-HSA-4090294
Synthesis of bile acids and bile salts R-HSA-192105
Gene expression (Transcription) R-HSA-74160
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
Biological oxidations R-HSA-211859
Cytochrome P450 - arranged by substrate type R-HSA-211897
Bile acid and bile salt metabolism R-HSA-194068
Nuclear Receptor transcription pathway R-HSA-383280
Phase I - Functionalization of compounds R-HSA-211945
Regulation of lipid metabolism by PPARalpha R-HSA-400206
SUMOylation R-HSA-2990846
Recycling of bile acids and salts R-HSA-159418
PPARA activates gene expression R-HSA-1989781
Endogenous sterols R-HSA-211976
Metabolism of proteins R-HSA-392499
Metabolism R-HSA-1430728
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Generic Transcription Pathway R-HSA-212436
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Biological oxidations R-HSA-211859
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Cytochrome P450 - arranged by substrate type R-HSA-211897
Endogenous sterols R-HSA-211976
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of steroids R-HSA-8957322
SUMOylation R-HSA-2990846
PPARA activates gene expression R-HSA-1989781
RNA Polymerase II Transcription R-HSA-73857
Recycling of bile acids and salts R-HSA-159418
Bile acid and bile salt metabolism R-HSA-194068
Post-translational protein modification R-HSA-597592
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
SUMOylation of intracellular receptors R-HSA-4090294
Metabolism of proteins R-HSA-392499
Nuclear Receptor transcription pathway R-HSA-383280
Recycling of bile acids and salts R-HSA-159418
RNA Polymerase II Transcription R-HSA-73857
Metabolism of lipids R-HSA-556833
Post-translational protein modification R-HSA-597592
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Bile acid and bile salt metabolism R-HSA-194068
Biological oxidations R-HSA-211859
Endogenous sterols R-HSA-211976
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Cytochrome P450 - arranged by substrate type R-HSA-211897
SUMOylation R-HSA-2990846
Generic Transcription Pathway R-HSA-212436
SUMOylation of intracellular receptors R-HSA-4090294
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Synthesis of bile acids and bile salts R-HSA-192105
Metabolism of steroids R-HSA-8957322
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160

Expression Atlas ENSG00000012504
NCBI gene (formerly Entrezgene) 9971
GeneCards 7967
HGNC Symbol HGNC:7967
MIM gene 603826
MIM morbid 617049
UniProtKB Gene Name Q96RI1
WikiGene 9971
Gene: THRB
Ensembl ID : ENSG00000151090
Description: thyroid hormone receptor beta
Gene Synonyms: C-ERBA-2,C-ERBA-BETA,ERBA-BETA,ERBA2,GRTH,NR1A2,PRTH,THR1,THRB1,THRB2,THRBETA,THRBETA1,THRBETA2,TRB,TRBETA,TRBETA1
3 APIs:
393 Possible Orthologues:

Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
Generic Transcription Pathway R-HSA-212436
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
Gene expression (Transcription) R-HSA-74160
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation of intracellular receptors R-HSA-4090294
Nuclear Receptor transcription pathway R-HSA-383280
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
SUMOylation R-HSA-2990846
Post-translational protein modification R-HSA-597592
RNA Polymerase II Transcription R-HSA-73857
SUMOylation of intracellular receptors R-HSA-4090294
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Nuclear Receptor transcription pathway R-HSA-383280
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
SUMOylation of intracellular receptors R-HSA-4090294
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
SUMOylation of intracellular receptors R-HSA-4090294
Nuclear Receptor transcription pathway R-HSA-383280
Metabolism of proteins R-HSA-392499
SUMOylation R-HSA-2990846
SUMOylation R-HSA-2990846
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Nuclear Receptor transcription pathway R-HSA-383280
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
SUMOylation of intracellular receptors R-HSA-4090294

Expression Atlas ENSG00000151090
NCBI gene (formerly Entrezgene) 7068
GeneCards 11799
HGNC Symbol HGNC:11799
MIM gene 190160
MIM morbid 274300
UniProtKB Gene Name P10828
WikiGene 7068
Gene: TP53
Ensembl ID : ENSG00000141510
Description: tumor protein p53
Gene Synonyms: LFS1,P53
3 APIs:
251 Possible Orthologues:

Pyroptosis R-HSA-5620971
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Signal Transduction R-HSA-162582
Transcriptional regulation by RUNX3 R-HSA-8878159
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Toll-like Receptor Cascades R-HSA-168898
MyD88 dependent cascade initiated on endosome R-HSA-975155
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Loss of Function of TP53 in Cancer R-HSA-9723907
Activation of PUMA and translocation to mitochondria R-HSA-139915
Chaperonin-mediated protein folding R-HSA-390466
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
G1/S DNA Damage Checkpoints R-HSA-69615
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
SUMOylation R-HSA-2990846
PTEN Regulation R-HSA-6807070
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Protein folding R-HSA-391251
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Signaling by NOTCH R-HSA-157118
Signaling by Interleukins R-HSA-449147
Oncogene Induced Senescence R-HSA-2559585
Regulation of TP53 Expression and Degradation R-HSA-6806003
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
p53-Dependent G1 DNA Damage Response R-HSA-69563
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
G2/M DNA damage checkpoint R-HSA-69473
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Mitotic G2-G2/M phases R-HSA-453274
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Cellular Senescence R-HSA-2559583
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Disease R-HSA-1643685
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Generic Transcription Pathway R-HSA-212436
Stabilization of p53 R-HSA-69541
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Regulation of TP53 Activity through Acetylation R-HSA-6804758
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular responses to stimuli R-HSA-8953897
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity through Methylation R-HSA-6804760
TP53 Regulates Metabolic Genes R-HSA-5628897
Immune System R-HSA-168256
Cellular responses to stress R-HSA-2262752
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Oxidative Stress Induced Senescence R-HSA-2559580
DNA Double-Strand Break Repair R-HSA-5693532
Diseases of programmed cell death R-HSA-9645723
G2/M Checkpoints R-HSA-69481
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Transition R-HSA-69275
Activation of NOXA and translocation to mitochondria R-HSA-111448
Ub-specific processing proteases R-HSA-5689880
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Regulation of PTEN gene transcription R-HSA-8943724
MyD88-independent TLR4 cascade R-HSA-166166
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by VENTX R-HSA-8853884
Hemostasis R-HSA-109582
PI5P Regulates TP53 Acetylation R-HSA-6811555
Pre-NOTCH Expression and Processing R-HSA-1912422
DNA Repair R-HSA-73894
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulated Necrosis R-HSA-5218859
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity R-HSA-5633007
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cell Cycle Checkpoints R-HSA-69620
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Apoptosis R-HSA-109581
SUMOylation of transcription factors R-HSA-3232118
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Transcriptional activation of p53 responsive genes R-HSA-69560
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
DNA Double Strand Break Response R-HSA-5693606
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Intrinsic Pathway for Apoptosis R-HSA-109606
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of TP53 Expression R-HSA-6804754
Pre-NOTCH Transcription and Translation R-HSA-1912408
Deubiquitination R-HSA-5688426
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Pyroptosis R-HSA-5620971
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Interleukin-1 family signaling R-HSA-446652
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Interleukin-1 signaling R-HSA-9020702
Regulation of TP53 Degradation R-HSA-6804757
Ovarian tumor domain proteases R-HSA-5689896
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of NF-kappa B signaling R-HSA-9758274
Cellular responses to stimuli R-HSA-8953897
G1/S DNA Damage Checkpoints R-HSA-69615
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Pyroptosis R-HSA-5620971
p53-Dependent G1 DNA Damage Response R-HSA-69563
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Cytokine Signaling in Immune system R-HSA-1280215
TP53 Regulates Metabolic Genes R-HSA-5628897
G2/M Checkpoints R-HSA-69481
Transcriptional activation of p53 responsive genes R-HSA-69560
Post-translational protein modification R-HSA-597592
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Immune System R-HSA-168256
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Diseases of programmed cell death R-HSA-9645723
Regulation of TP53 Expression and Degradation R-HSA-6806003
Loss of Function of TP53 in Cancer R-HSA-9723907
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Transcriptional regulation by RUNX3 R-HSA-8878159
SUMOylation of transcription factors R-HSA-3232118
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Intrinsic Pathway for Apoptosis R-HSA-109606
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Oxidative Stress Induced Senescence R-HSA-2559580
Hemostasis R-HSA-109582
Pre-NOTCH Transcription and Translation R-HSA-1912408
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88-independent TLR4 cascade R-HSA-166166
Transcriptional Regulation by VENTX R-HSA-8853884
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Activation of BH3-only proteins R-HSA-114452
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
PTEN Regulation R-HSA-6807070
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Factors involved in megakaryocyte development and platelet production R-HSA-983231
G2/M Transition R-HSA-69275
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Regulation of PTEN gene transcription R-HSA-8943724
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chaperonin-mediated protein folding R-HSA-390466
DNA Repair R-HSA-73894
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Activation of PUMA and translocation to mitochondria R-HSA-139915
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double-Strand Break Repair R-HSA-5693532
Generic Transcription Pathway R-HSA-212436
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle Checkpoints R-HSA-69620
Activation of NOXA and translocation to mitochondria R-HSA-111448
Cell Cycle, Mitotic R-HSA-69278
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Signaling by NOTCH R-HSA-157118
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Programmed Cell Death R-HSA-5357801
G2/M DNA damage checkpoint R-HSA-69473
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Regulated Necrosis R-HSA-5218859
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulation of TP53 Expression R-HSA-6804754
PI5P Regulates TP53 Acetylation R-HSA-6811555
Signal Transduction R-HSA-162582
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Ovarian tumor domain proteases R-HSA-5689896
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
DNA Double Strand Break Response R-HSA-5693606
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cellular Senescence R-HSA-2559583
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Protein folding R-HSA-391251
Regulation of TP53 Activity R-HSA-5633007
Pre-NOTCH Expression and Processing R-HSA-1912422
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Programmed Cell Death R-HSA-5357801
Regulation of PTEN gene transcription R-HSA-8943724
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cell Cycle R-HSA-1640170
SUMOylation of transcription factors R-HSA-3232118
Transcriptional Regulation by VENTX R-HSA-8853884
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Activation of NOXA and translocation to mitochondria R-HSA-111448
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cell Cycle, Mitotic R-HSA-69278
Intracellular signaling by second messengers R-HSA-9006925
DNA Double-Strand Break Repair R-HSA-5693532
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
G1/S DNA Damage Checkpoints R-HSA-69615
MyD88 cascade initiated on plasma membrane R-HSA-975871
SUMOylation R-HSA-2990846
Oncogene Induced Senescence R-HSA-2559585
G2/M Checkpoints R-HSA-69481
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Expression R-HSA-6804754
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity R-HSA-5633007
Protein folding R-HSA-391251
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Oxidative Stress Induced Senescence R-HSA-2559580
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Chaperonin-mediated protein folding R-HSA-390466
Signaling by NOTCH R-HSA-157118
Immune System R-HSA-168256
Deubiquitination R-HSA-5688426
Regulated Necrosis R-HSA-5218859
Transcriptional regulation by RUNX3 R-HSA-8878159
Cellular responses to stimuli R-HSA-8953897
Activation of BH3-only proteins R-HSA-114452
Ub-specific processing proteases R-HSA-5689880
Stabilization of p53 R-HSA-69541
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Post-translational protein modification R-HSA-597592
Hemostasis R-HSA-109582
Transcriptional activation of p53 responsive genes R-HSA-69560
p53-Dependent G1 DNA Damage Response R-HSA-69563
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
PI5P Regulates TP53 Acetylation R-HSA-6811555
Pyroptosis R-HSA-5620971
Loss of Function of TP53 in Cancer R-HSA-9723907
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DNA Repair R-HSA-73894
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
PTEN Regulation R-HSA-6807070
MyD88 dependent cascade initiated on endosome R-HSA-975155
G2/M Transition R-HSA-69275
Diseases of programmed cell death R-HSA-9645723
PIP3 activates AKT signaling R-HSA-1257604
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Generic Transcription Pathway R-HSA-212436
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Activation of PUMA and translocation to mitochondria R-HSA-139915
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
TP53 Regulates Metabolic Genes R-HSA-5628897
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Apoptosis R-HSA-109581
Interleukin-1 signaling R-HSA-9020702
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 family signaling R-HSA-446652
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular Senescence R-HSA-2559583
DNA Double Strand Break Response R-HSA-5693606
Pre-NOTCH Expression and Processing R-HSA-1912422
RUNX3 regulates CDKN1A transcription R-HSA-8941855
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Methylation R-HSA-6804760
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
G2/M DNA damage checkpoint R-HSA-69473
Cell Cycle Checkpoints R-HSA-69620
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Transcriptional Regulation by TP53 R-HSA-3700989
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Intrinsic Pathway for Apoptosis R-HSA-109606
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Mitotic G2-G2/M phases R-HSA-453274
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Regulation of NF-kappa B signaling R-HSA-9758274
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Ovarian tumor domain proteases R-HSA-5689896
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Metabolism of proteins R-HSA-392499
Gene expression (Transcription) R-HSA-74160
Signaling by Interleukins R-HSA-449147
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
DNA Repair R-HSA-73894
Oxidative Stress Induced Senescence R-HSA-2559580
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
Regulation of TP53 Expression R-HSA-6804754
Signaling by Interleukins R-HSA-449147
Intracellular signaling by second messengers R-HSA-9006925
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 cascade initiated on plasma membrane R-HSA-975871
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Ub-specific processing proteases R-HSA-5689880
Cell Cycle R-HSA-1640170
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Activation of PUMA and translocation to mitochondria R-HSA-139915
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cell Cycle, Mitotic R-HSA-69278
Cellular Senescence R-HSA-2559583
Signal Transduction R-HSA-162582
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PIP3 activates AKT signaling R-HSA-1257604
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Regulation of NF-kappa B signaling R-HSA-9758274
Cell Cycle Checkpoints R-HSA-69620
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of PTEN gene transcription R-HSA-8943724
Regulation of TP53 Activity through Methylation R-HSA-6804760
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Transcriptional regulation by RUNX3 R-HSA-8878159
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Ovarian tumor domain proteases R-HSA-5689896
Signaling by NOTCH R-HSA-157118
Activation of NOXA and translocation to mitochondria R-HSA-111448
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Loss of Function of TP53 in Cancer R-HSA-9723907
Pre-NOTCH Expression and Processing R-HSA-1912422
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Transcriptional Regulation by TP53 R-HSA-3700989
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DNA Double Strand Break Response R-HSA-5693606
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMOylation of transcription factors R-HSA-3232118
Post-translational protein modification R-HSA-597592
Mitotic G2-G2/M phases R-HSA-453274
Regulation of TP53 Degradation R-HSA-6804757
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Activity R-HSA-5633007
DNA Double-Strand Break Repair R-HSA-5693532
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
G2/M Checkpoints R-HSA-69481
Regulated Necrosis R-HSA-5218859
TP53 Regulates Metabolic Genes R-HSA-5628897
Cellular responses to stimuli R-HSA-8953897
SUMOylation R-HSA-2990846
Hemostasis R-HSA-109582
Deubiquitination R-HSA-5688426
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Metabolism of proteins R-HSA-392499
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional activation of p53 responsive genes R-HSA-69560
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Pre-NOTCH Transcription and Translation R-HSA-1912408
p53-Dependent G1 DNA Damage Response R-HSA-69563
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Diseases of programmed cell death R-HSA-9645723
Oncogene Induced Senescence R-HSA-2559585
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Programmed Cell Death R-HSA-5357801
Chaperonin-mediated protein folding R-HSA-390466
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
PTEN Regulation R-HSA-6807070
Activation of BH3-only proteins R-HSA-114452
Apoptosis R-HSA-109581
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Transcriptional Regulation by VENTX R-HSA-8853884
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Immune System R-HSA-168256
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Pyroptosis R-HSA-5620971
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Intrinsic Pathway for Apoptosis R-HSA-109606
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Protein folding R-HSA-391251
Regulation of PTEN gene transcription R-HSA-8943724
Regulation of TP53 Degradation R-HSA-6804757
Regulation of NF-kappa B signaling R-HSA-9758274
Transcriptional activation of p53 responsive genes R-HSA-69560
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 family signaling R-HSA-446652
DNA Repair R-HSA-73894
MyD88-independent TLR4 cascade R-HSA-166166
Gene expression (Transcription) R-HSA-74160
Pre-NOTCH Transcription and Translation R-HSA-1912408
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
SUMOylation of transcription factors R-HSA-3232118
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Diseases of programmed cell death R-HSA-9645723
Stabilization of p53 R-HSA-69541
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 Regulates Metabolic Genes R-HSA-5628897
Disease R-HSA-1643685
Generic Transcription Pathway R-HSA-212436
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DNA Double Strand Break Response R-HSA-5693606
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular Senescence R-HSA-2559583
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Ub-specific processing proteases R-HSA-5689880
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Protein folding R-HSA-391251
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Oxidative Stress Induced Senescence R-HSA-2559580
Cell Cycle R-HSA-1640170
MyD88 dependent cascade initiated on endosome R-HSA-975155
Regulated Necrosis R-HSA-5218859
Activation of PUMA and translocation to mitochondria R-HSA-139915
Activation of BH3-only proteins R-HSA-114452
Programmed Cell Death R-HSA-5357801
Signaling by NOTCH R-HSA-157118
Innate Immune System R-HSA-168249
Chaperonin-mediated protein folding R-HSA-390466
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional Regulation by VENTX R-HSA-8853884
G2/M DNA damage checkpoint R-HSA-69473
Intrinsic Pathway for Apoptosis R-HSA-109606
Transcriptional Regulation by TP53 R-HSA-3700989
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Transcriptional regulation by RUNX3 R-HSA-8878159
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Deubiquitination R-HSA-5688426
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Apoptosis R-HSA-109581
Toll-like Receptor Cascades R-HSA-168898
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Pyroptosis R-HSA-5620971
Regulation of TP53 Expression R-HSA-6804754
G2/M Checkpoints R-HSA-69481
Ovarian tumor domain proteases R-HSA-5689896
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Oncogene Induced Senescence R-HSA-2559585
Pre-NOTCH Expression and Processing R-HSA-1912422
Post-translational protein modification R-HSA-597592
Immune System R-HSA-168256
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
G2/M Transition R-HSA-69275
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity R-HSA-5633007
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Intracellular signaling by second messengers R-HSA-9006925
Hemostasis R-HSA-109582
Loss of Function of TP53 in Cancer R-HSA-9723907
Mitotic G2-G2/M phases R-HSA-453274
Activation of NOXA and translocation to mitochondria R-HSA-111448
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SUMOylation R-HSA-2990846
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signal Transduction R-HSA-162582
DNA Double-Strand Break Repair R-HSA-5693532
RNA Polymerase II Transcription R-HSA-73857
PIP3 activates AKT signaling R-HSA-1257604
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Cellular responses to stimuli R-HSA-8953897
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
Activation of NOXA and translocation to mitochondria R-HSA-111448
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Hemostasis R-HSA-109582
Regulated Necrosis R-HSA-5218859
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Transcriptional Regulation by VENTX R-HSA-8853884
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle, Mitotic R-HSA-69278
Regulation of PTEN gene transcription R-HSA-8943724
DNA Double Strand Break Response R-HSA-5693606
Regulation of TP53 Activity R-HSA-5633007
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Transition R-HSA-69275
MyD88 cascade initiated on plasma membrane R-HSA-975871
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RUNX3 regulates CDKN1A transcription R-HSA-8941855
DNA Repair R-HSA-73894
Programmed Cell Death R-HSA-5357801
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
SUMOylation R-HSA-2990846
DNA Double-Strand Break Repair R-HSA-5693532
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Pre-NOTCH Transcription and Translation R-HSA-1912408
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Signaling by NOTCH R-HSA-157118
Cell Cycle Checkpoints R-HSA-69620
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Ub-specific processing proteases R-HSA-5689880
Metabolism of proteins R-HSA-392499
Loss of Function of TP53 in Cancer R-HSA-9723907
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Activation of PUMA and translocation to mitochondria R-HSA-139915
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Stabilization of p53 R-HSA-69541
Cytokine Signaling in Immune system R-HSA-1280215
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
Pre-NOTCH Expression and Processing R-HSA-1912422
Diseases of programmed cell death R-HSA-9645723
Transcriptional regulation by RUNX3 R-HSA-8878159
Signal Transduction R-HSA-162582
Regulation of TP53 Degradation R-HSA-6804757
TP53 Regulates Metabolic Genes R-HSA-5628897
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
MyD88 dependent cascade initiated on endosome R-HSA-975155
G1/S DNA Damage Checkpoints R-HSA-69615
Oxidative Stress Induced Senescence R-HSA-2559580
Transcriptional Regulation by TP53 R-HSA-3700989
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
PTEN Regulation R-HSA-6807070
Regulation of TP53 Expression and Degradation R-HSA-6806003
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Expression R-HSA-6804754
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Activation of BH3-only proteins R-HSA-114452
Signaling by Interleukins R-HSA-449147
Oncogene Induced Senescence R-HSA-2559585
Cellular Senescence R-HSA-2559583
Interleukin-1 signaling R-HSA-9020702
Transcriptional activation of p53 responsive genes R-HSA-69560
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Intracellular signaling by second messengers R-HSA-9006925
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
G2/M Checkpoints R-HSA-69481
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Mitotic G2-G2/M phases R-HSA-453274
Apoptosis R-HSA-109581
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Protein folding R-HSA-391251
Disease R-HSA-1643685
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Post-translational protein modification R-HSA-597592
Pyroptosis R-HSA-5620971
Cell Cycle R-HSA-1640170
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Chaperonin-mediated protein folding R-HSA-390466
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Ovarian tumor domain proteases R-HSA-5689896
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of TP53 Activity through Methylation R-HSA-6804760
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RNA Polymerase II Transcription R-HSA-73857
G2/M DNA damage checkpoint R-HSA-69473
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
SUMOylation of transcription factors R-HSA-3232118
Immune System R-HSA-168256
Gene expression (Transcription) R-HSA-74160
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Pyroptosis R-HSA-5620971
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Ub-specific processing proteases R-HSA-5689880
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulated Necrosis R-HSA-5218859
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of TP53 Expression and Degradation R-HSA-6806003
Stabilization of p53 R-HSA-69541
PI5P Regulates TP53 Acetylation R-HSA-6811555
Cell Cycle, Mitotic R-HSA-69278
Gene expression (Transcription) R-HSA-74160
MyD88 dependent cascade initiated on endosome R-HSA-975155
Ovarian tumor domain proteases R-HSA-5689896
Pre-NOTCH Expression and Processing R-HSA-1912422
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Regulation of TP53 Degradation R-HSA-6804757
G2/M Transition R-HSA-69275
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Transcriptional Regulation by VENTX R-HSA-8853884
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Disease R-HSA-1643685
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity through Acetylation R-HSA-6804758
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Activation of PUMA and translocation to mitochondria R-HSA-139915
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll-like Receptor Cascades R-HSA-168898
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Signal Transduction R-HSA-162582
Loss of Function of TP53 in Cancer R-HSA-9723907
Oxidative Stress Induced Senescence R-HSA-2559580
Hemostasis R-HSA-109582
SUMOylation of transcription factors R-HSA-3232118
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
PTEN Regulation R-HSA-6807070
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Expression R-HSA-6804754
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Pre-NOTCH Transcription and Translation R-HSA-1912408
Cellular Senescence R-HSA-2559583
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
DNA Repair R-HSA-73894
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Post-translational protein modification R-HSA-597592
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
G2/M Checkpoints R-HSA-69481
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Oncogene Induced Senescence R-HSA-2559585
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Generic Transcription Pathway R-HSA-212436
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of NF-kappa B signaling R-HSA-9758274
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Diseases of programmed cell death R-HSA-9645723
Transcriptional activation of p53 responsive genes R-HSA-69560
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
DNA Double-Strand Break Repair R-HSA-5693532
Programmed Cell Death R-HSA-5357801
RUNX3 regulates CDKN1A transcription R-HSA-8941855
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Activation of NOXA and translocation to mitochondria R-HSA-111448
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Intrinsic Pathway for Apoptosis R-HSA-109606
Chaperonin-mediated protein folding R-HSA-390466
Mitotic G2-G2/M phases R-HSA-453274
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signaling by NOTCH R-HSA-157118
TP53 Regulates Metabolic Genes R-HSA-5628897
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Immune System R-HSA-168256
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Cell Cycle R-HSA-1640170
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of PTEN gene transcription R-HSA-8943724
Transcriptional Regulation by TP53 R-HSA-3700989
PIP3 activates AKT signaling R-HSA-1257604
Factors involved in megakaryocyte development and platelet production R-HSA-983231
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Protein folding R-HSA-391251
Intracellular signaling by second messengers R-HSA-9006925
SUMOylation R-HSA-2990846
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
RNA Polymerase II Transcription R-HSA-73857
Cellular responses to stimuli R-HSA-8953897
DNA Double Strand Break Response R-HSA-5693606
Cellular responses to stress R-HSA-2262752
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Innate Immune System R-HSA-168249
Transcriptional regulation by RUNX3 R-HSA-8878159
Apoptosis R-HSA-109581
Activation of BH3-only proteins R-HSA-114452
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity R-HSA-5633007
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Immune System R-HSA-168256
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Transcriptional activation of p53 responsive genes R-HSA-69560
Cytokine Signaling in Immune system R-HSA-1280215
Cellular responses to stress R-HSA-2262752
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Regulation of TP53 Expression R-HSA-6804754
Metabolism of proteins R-HSA-392499
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Loss of Function of TP53 in Cancer R-HSA-9723907
Transcriptional Regulation by VENTX R-HSA-8853884
SUMOylation R-HSA-2990846
SUMOylation of transcription factors R-HSA-3232118
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
G2/M Transition R-HSA-69275
Ub-specific processing proteases R-HSA-5689880
Generic Transcription Pathway R-HSA-212436
G2/M DNA damage checkpoint R-HSA-69473
Regulation of TP53 Activity R-HSA-5633007
Pyroptosis R-HSA-5620971
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxidative Stress Induced Senescence R-HSA-2559580
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cell Cycle Checkpoints R-HSA-69620
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Toll-like Receptor Cascades R-HSA-168898
Stabilization of p53 R-HSA-69541
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Signaling by Interleukins R-HSA-449147
Diseases of programmed cell death R-HSA-9645723
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
G1/S DNA Damage Checkpoints R-HSA-69615
Activation of PUMA and translocation to mitochondria R-HSA-139915
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
G2/M Checkpoints R-HSA-69481
Deubiquitination R-HSA-5688426
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Cellular Senescence R-HSA-2559583
Mitotic G2-G2/M phases R-HSA-453274
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cellular responses to stimuli R-HSA-8953897
Oncogene Induced Senescence R-HSA-2559585
Signal Transduction R-HSA-162582
DNA Double Strand Break Response R-HSA-5693606
Apoptosis R-HSA-109581
Pre-NOTCH Transcription and Translation R-HSA-1912408
Gene expression (Transcription) R-HSA-74160
Ovarian tumor domain proteases R-HSA-5689896
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Interleukin-1 family signaling R-HSA-446652
Activation of BH3-only proteins R-HSA-114452
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Regulation of TP53 Expression and Degradation R-HSA-6806003
PI5P Regulates TP53 Acetylation R-HSA-6811555
Regulation of TP53 Degradation R-HSA-6804757
Pre-NOTCH Expression and Processing R-HSA-1912422
MyD88-independent TLR4 cascade R-HSA-166166
Regulation of NF-kappa B signaling R-HSA-9758274
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Interleukin-1 signaling R-HSA-9020702
Regulation of PTEN gene transcription R-HSA-8943724
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Innate Immune System R-HSA-168249
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DNA Double-Strand Break Repair R-HSA-5693532
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Programmed Cell Death R-HSA-5357801
Cell Cycle, Mitotic R-HSA-69278
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Protein folding R-HSA-391251
TP53 Regulates Metabolic Genes R-HSA-5628897
Transcriptional Regulation by TP53 R-HSA-3700989
Intrinsic Pathway for Apoptosis R-HSA-109606
DNA Repair R-HSA-73894
Post-translational protein modification R-HSA-597592
Cell Cycle R-HSA-1640170
Transcriptional regulation by RUNX3 R-HSA-8878159
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Activity through Methylation R-HSA-6804760
Signaling by NOTCH R-HSA-157118
Regulated Necrosis R-HSA-5218859
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
p53-Dependent G1 DNA Damage Response R-HSA-69563
PTEN Regulation R-HSA-6807070
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
PIP3 activates AKT signaling R-HSA-1257604
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Chaperonin-mediated protein folding R-HSA-390466
Hemostasis R-HSA-109582
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Disease R-HSA-1643685
Activation of NOXA and translocation to mitochondria R-HSA-111448
G2/M Checkpoints R-HSA-69481
Pre-NOTCH Transcription and Translation R-HSA-1912408
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Generic Transcription Pathway R-HSA-212436
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of PTEN gene transcription R-HSA-8943724
Cell Cycle R-HSA-1640170
Activation of NOXA and translocation to mitochondria R-HSA-111448
Regulation of NF-kappa B signaling R-HSA-9758274
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMOylation of transcription factors R-HSA-3232118
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Cellular responses to stress R-HSA-2262752
PTEN Regulation R-HSA-6807070
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Transcriptional Regulation by VENTX R-HSA-8853884
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional activation of p53 responsive genes R-HSA-69560
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Degradation R-HSA-6804757
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Transcriptional regulation by RUNX3 R-HSA-8878159
Pre-NOTCH Expression and Processing R-HSA-1912422
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Regulated Necrosis R-HSA-5218859
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
RNA Polymerase II Transcription R-HSA-73857
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Regulation of TP53 Expression R-HSA-6804754
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Disease R-HSA-1643685
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Chaperonin-mediated protein folding R-HSA-390466
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Hemostasis R-HSA-109582
Ub-specific processing proteases R-HSA-5689880
Oncogene Induced Senescence R-HSA-2559585
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 signaling R-HSA-9020702
G2/M DNA damage checkpoint R-HSA-69473
G2/M Transition R-HSA-69275
MyD88-independent TLR4 cascade R-HSA-166166
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Regulation of TP53 Activity through Methylation R-HSA-6804760
Stabilization of p53 R-HSA-69541
Cell Cycle, Mitotic R-HSA-69278
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Programmed Cell Death R-HSA-5357801
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll-like Receptor Cascades R-HSA-168898
SUMOylation R-HSA-2990846
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Mitotic G2-G2/M phases R-HSA-453274
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Cytokine Signaling in Immune system R-HSA-1280215
Activation of PUMA and translocation to mitochondria R-HSA-139915
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity R-HSA-5633007
Innate Immune System R-HSA-168249
Loss of Function of TP53 in Cancer R-HSA-9723907
Intracellular signaling by second messengers R-HSA-9006925
Apoptosis R-HSA-109581
Diseases of programmed cell death R-HSA-9645723
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
MyD88 dependent cascade initiated on endosome R-HSA-975155
Post-translational protein modification R-HSA-597592
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Factors involved in megakaryocyte development and platelet production R-HSA-983231
p53-Dependent G1 DNA Damage Response R-HSA-69563
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Immune System R-HSA-168256
TP53 Regulates Metabolic Genes R-HSA-5628897
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Oxidative Stress Induced Senescence R-HSA-2559580
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Transcriptional Regulation by TP53 R-HSA-3700989
Protein folding R-HSA-391251
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Signaling by NOTCH R-HSA-157118
PI5P Regulates TP53 Acetylation R-HSA-6811555
DNA Double-Strand Break Repair R-HSA-5693532
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cellular responses to stimuli R-HSA-8953897
PIP3 activates AKT signaling R-HSA-1257604
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
MyD88 cascade initiated on plasma membrane R-HSA-975871
Ovarian tumor domain proteases R-HSA-5689896
DNA Repair R-HSA-73894
Cellular Senescence R-HSA-2559583
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
DNA Double Strand Break Response R-HSA-5693606
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Toll-like Receptor Cascades R-HSA-168898
Loss of Function of TP53 in Cancer R-HSA-9723907
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Pre-NOTCH Transcription and Translation R-HSA-1912408
Activation of NOXA and translocation to mitochondria R-HSA-111448
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cell Cycle Checkpoints R-HSA-69620
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Cell Cycle R-HSA-1640170
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Mitotic G2-G2/M phases R-HSA-453274
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double-Strand Break Repair R-HSA-5693532
G2/M Transition R-HSA-69275
Activation of BH3-only proteins R-HSA-114452
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signal Transduction R-HSA-162582
DNA Repair R-HSA-73894
Deubiquitination R-HSA-5688426
Pre-NOTCH Expression and Processing R-HSA-1912422
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Metabolism of proteins R-HSA-392499
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
Interleukin-1 signaling R-HSA-9020702
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Cell Cycle, Mitotic R-HSA-69278
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
G2/M Checkpoints R-HSA-69481
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Pyroptosis R-HSA-5620971
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
Interleukin-1 family signaling R-HSA-446652
Protein folding R-HSA-391251
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Hemostasis R-HSA-109582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TP53 Activity through Methylation R-HSA-6804760
Generic Transcription Pathway R-HSA-212436
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Chaperonin-mediated protein folding R-HSA-390466
PI5P Regulates TP53 Acetylation R-HSA-6811555
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Intrinsic Pathway for Apoptosis R-HSA-109606
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PTEN Regulation R-HSA-6807070
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Regulation of PTEN gene transcription R-HSA-8943724
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Innate Immune System R-HSA-168249
Cellular responses to stimuli R-HSA-8953897
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
MyD88 cascade initiated on plasma membrane R-HSA-975871
TP53 Regulates Metabolic Genes R-HSA-5628897
p53-Dependent G1 DNA Damage Response R-HSA-69563
Immune System R-HSA-168256
Regulated Necrosis R-HSA-5218859
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Acetylation R-HSA-6804758
Transcriptional activation of p53 responsive genes R-HSA-69560
G2/M DNA damage checkpoint R-HSA-69473
RUNX3 regulates CDKN1A transcription R-HSA-8941855
Oxidative Stress Induced Senescence R-HSA-2559580
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by Interleukins R-HSA-449147
SUMOylation R-HSA-2990846
Diseases of programmed cell death R-HSA-9645723
MyD88 dependent cascade initiated on endosome R-HSA-975155
DNA Double Strand Break Response R-HSA-5693606
Gene expression (Transcription) R-HSA-74160
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Transcriptional Regulation by VENTX R-HSA-8853884
Cellular Senescence R-HSA-2559583
Regulation of TP53 Expression R-HSA-6804754
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
Factors involved in megakaryocyte development and platelet production R-HSA-983231
Oncogene Induced Senescence R-HSA-2559585
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Ovarian tumor domain proteases R-HSA-5689896
Programmed Cell Death R-HSA-5357801
Regulation of TP53 Expression and Degradation R-HSA-6806003
Activation of PUMA and translocation to mitochondria R-HSA-139915
G1/S DNA Damage Checkpoints R-HSA-69615
Cytokine Signaling in Immune system R-HSA-1280215
SUMOylation of transcription factors R-HSA-3232118
Cellular responses to stress R-HSA-2262752
Stabilization of p53 R-HSA-69541
Signaling by NOTCH R-HSA-157118
Pyroptosis R-HSA-5620971
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
PTEN Regulation R-HSA-6807070
TP53 Regulates Metabolic Genes R-HSA-5628897
MyD88 dependent cascade initiated on endosome R-HSA-975155
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Oxidative Stress Induced Senescence R-HSA-2559580
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Mitotic G2-G2/M phases R-HSA-453274
Protein folding R-HSA-391251
Regulation of PTEN gene transcription R-HSA-8943724
G2/M Checkpoints R-HSA-69481
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586
Transcriptional regulation by RUNX3 R-HSA-8878159
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116
Cell Cycle Checkpoints R-HSA-69620
Deubiquitination R-HSA-5688426
G2/M DNA damage checkpoint R-HSA-69473
G2/M Transition R-HSA-69275
Cell Cycle, Mitotic R-HSA-69278
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115
Oncogene Induced Senescence R-HSA-2559585
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
DNA Double-Strand Break Repair R-HSA-5693532
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Activation of NOXA and translocation to mitochondria R-HSA-111448
Activation of BH3-only proteins R-HSA-114452
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of TP53 Activity through Acetylation R-HSA-6804758
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MyD88-independent TLR4 cascade R-HSA-166166
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
PI5P Regulates TP53 Acetylation R-HSA-6811555
Generic Transcription Pathway R-HSA-212436
Signaling by NOTCH R-HSA-157118
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008
Diseases of programmed cell death R-HSA-9645723
RNA Polymerase II Transcription R-HSA-73857
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648
G1/S DNA Damage Checkpoints R-HSA-69615
MyD88 cascade initiated on plasma membrane R-HSA-975871
DNA Repair R-HSA-73894
Regulation of TP53 Degradation R-HSA-6804757
Apoptosis R-HSA-109581
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Regulation of TP53 Expression R-HSA-6804754
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
Transcriptional Regulation by VENTX R-HSA-8853884
SUMOylation of transcription factors R-HSA-3232118
Transcriptional Regulation by TP53 R-HSA-3700989
DNA Double Strand Break Response R-HSA-5693606
Regulation of NF-kappa B signaling R-HSA-9758274
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584
Post-translational protein modification R-HSA-597592
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Activation of PUMA and translocation to mitochondria R-HSA-139915
Factors involved in megakaryocyte development and platelet production R-HSA-983231
RUNX3 regulates CDKN1A transcription R-HSA-8941855
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Regulation of TP53 Activity R-HSA-5633007
Ovarian tumor domain proteases R-HSA-5689896
Signaling by Interleukins R-HSA-449147
Transcriptional activation of p53 responsive genes R-HSA-69560
Regulated Necrosis R-HSA-5218859
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471
Ub-specific processing proteases R-HSA-5689880
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Disease R-HSA-1643685
Cellular responses to stress R-HSA-2262752
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895
p53-Dependent G1 DNA Damage Response R-HSA-69563
Toll-like Receptor Cascades R-HSA-168898
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009
Immune System R-HSA-168256
Intrinsic Pathway for Apoptosis R-HSA-109606
Hemostasis R-HSA-109582
Regulation of TP53 Expression and Degradation R-HSA-6806003
PIP3 activates AKT signaling R-HSA-1257604
Pre-NOTCH Transcription and Translation R-HSA-1912408
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Pre-NOTCH Expression and Processing R-HSA-1912422
Innate Immune System R-HSA-168249
Regulation of TP53 Activity through Methylation R-HSA-6804760
Loss of Function of TP53 in Cancer R-HSA-9723907
SUMOylation R-HSA-2990846
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205
Stabilization of p53 R-HSA-69541
Chaperonin-mediated protein folding R-HSA-390466
Metabolism of proteins R-HSA-392499

Expression Atlas ENSG00000141510
LRG display in Ensembl gene LRG_321
NCBI gene (formerly Entrezgene) 7157
GeneCards 11998
HGNC Symbol HGNC:11998
MIM gene 191170
MIM morbid 618165
UniProtKB Gene Name P04637
WikiGene 7157
Gene: PPARG
Ensembl ID : ENSG00000132170
Description: peroxisome proliferator activated receptor gamma
Gene Synonyms: NR1C3,PPARG1,PPARG2,PPARGAMMA
35 APIs:
406 Possible Orthologues:

Nuclear Receptor transcription pathway R-HSA-383280
MECP2 regulates transcription factors R-HSA-9022707
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional Regulation by MECP2 R-HSA-8986944
Metabolism of lipids R-HSA-556833
Developmental Biology R-HSA-1266738
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PPARA activates gene expression R-HSA-1989781
RNA Polymerase II Transcription R-HSA-73857
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Regulation of PTEN gene transcription R-HSA-8943724
Generic Transcription Pathway R-HSA-212436
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Signal Transduction R-HSA-162582
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
SUMOylation R-HSA-2990846
Post-translational protein modification R-HSA-597592
SUMOylation of intracellular receptors R-HSA-4090294
Metabolism of lipids R-HSA-556833
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PIP3 activates AKT signaling R-HSA-1257604
Nuclear Receptor transcription pathway R-HSA-383280
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
PPARA activates gene expression R-HSA-1989781
MECP2 regulates transcription factors R-HSA-9022707
PTEN Regulation R-HSA-6807070
Regulation of lipid metabolism by PPARalpha R-HSA-400206
SUMOylation of intracellular receptors R-HSA-4090294
Post-translational protein modification R-HSA-597592
Regulation of PTEN gene transcription R-HSA-8943724
SUMOylation R-HSA-2990846
Transcriptional Regulation by MECP2 R-HSA-8986944
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Transcriptional Regulation by MECP2 R-HSA-8986944
PTEN Regulation R-HSA-6807070
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Regulation of PTEN gene transcription R-HSA-8943724
Developmental Biology R-HSA-1266738
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation R-HSA-2990846
Metabolism of lipids R-HSA-556833
Signal Transduction R-HSA-162582
PPARA activates gene expression R-HSA-1989781
SUMOylation of intracellular receptors R-HSA-4090294
Intracellular signaling by second messengers R-HSA-9006925
MECP2 regulates transcription factors R-HSA-9022707
RNA Polymerase II Transcription R-HSA-73857
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Developmental Biology R-HSA-1266738
Regulation of PTEN gene transcription R-HSA-8943724
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional Regulation by MECP2 R-HSA-8986944
Metabolism R-HSA-1430728
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
SUMOylation of intracellular receptors R-HSA-4090294
PTEN Regulation R-HSA-6807070
Regulation of lipid metabolism by PPARalpha R-HSA-400206
SUMOylation R-HSA-2990846
Metabolism of proteins R-HSA-392499
Metabolism of lipids R-HSA-556833
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
PPARA activates gene expression R-HSA-1989781
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
Generic Transcription Pathway R-HSA-212436
MECP2 regulates transcription factors R-HSA-9022707
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
RNA Polymerase II Transcription R-HSA-73857
Post-translational protein modification R-HSA-597592
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional Regulation by MECP2 R-HSA-8986944
Metabolism of lipids R-HSA-556833
MECP2 regulates transcription factors R-HSA-9022707
SUMOylation R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Nuclear Receptor transcription pathway R-HSA-383280
Signal Transduction R-HSA-162582
Regulation of PTEN gene transcription R-HSA-8943724
SUMOylation of intracellular receptors R-HSA-4090294
PPARA activates gene expression R-HSA-1989781
Metabolism of proteins R-HSA-392499
Intracellular signaling by second messengers R-HSA-9006925
Regulation of lipid metabolism by PPARalpha R-HSA-400206
Developmental Biology R-HSA-1266738
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
Metabolism R-HSA-1430728
Signal Transduction R-HSA-162582
PIP3 activates AKT signaling R-HSA-1257604
Gene expression (Transcription) R-HSA-74160
Nuclear Receptor transcription pathway R-HSA-383280
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PPARA activates gene expression R-HSA-1989781
Generic Transcription Pathway R-HSA-212436
Regulation of lipid metabolism by PPARalpha R-HSA-400206
MECP2 regulates transcription factors R-HSA-9022707
Post-translational protein modification R-HSA-597592
SUMOylation of intracellular receptors R-HSA-4090294
Transcriptional Regulation by MECP2 R-HSA-8986944
Regulation of PTEN gene transcription R-HSA-8943724
SUMOylation R-HSA-2990846
Metabolism of lipids R-HSA-556833
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Gene expression (Transcription) R-HSA-74160
Regulation of PTEN gene transcription R-HSA-8943724
Generic Transcription Pathway R-HSA-212436
Nuclear Receptor transcription pathway R-HSA-383280
PIP3 activates AKT signaling R-HSA-1257604
RNA Polymerase II Transcription R-HSA-73857
SUMOylation of intracellular receptors R-HSA-4090294
Developmental Biology R-HSA-1266738
MECP2 regulates transcription factors R-HSA-9022707
Post-translational protein modification R-HSA-597592
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of lipids R-HSA-556833
SUMOylation R-HSA-2990846
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transcriptional Regulation by MECP2 R-HSA-8986944
Metabolism R-HSA-1430728
PPARA activates gene expression R-HSA-1989781
Regulation of lipid metabolism by PPARalpha R-HSA-400206
PTEN Regulation R-HSA-6807070
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
MECP2 regulates transcription factors R-HSA-9022707
Metabolism R-HSA-1430728
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of PTEN gene transcription R-HSA-8943724
Nuclear Receptor transcription pathway R-HSA-383280
SUMOylation of intracellular receptors R-HSA-4090294
SUMOylation R-HSA-2990846
Metabolism of lipids R-HSA-556833
Gene expression (Transcription) R-HSA-74160
PPARA activates gene expression R-HSA-1989781
Developmental Biology R-HSA-1266738
Intracellular signaling by second messengers R-HSA-9006925
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Regulation of lipid metabolism by PPARalpha R-HSA-400206
PTEN Regulation R-HSA-6807070
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by MECP2 R-HSA-8986944
PIP3 activates AKT signaling R-HSA-1257604
SUMOylation R-HSA-2990846
Nuclear Receptor transcription pathway R-HSA-383280
Post-translational protein modification R-HSA-597592
Signal Transduction R-HSA-162582
Metabolism of lipids R-HSA-556833
PPARA activates gene expression R-HSA-1989781
Developmental Biology R-HSA-1266738
Regulation of lipid metabolism by PPARalpha R-HSA-400206
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by MECP2 R-HSA-8986944
SUMOylation of intracellular receptors R-HSA-4090294
Regulation of PTEN gene transcription R-HSA-8943724
Metabolism of proteins R-HSA-392499
PIP3 activates AKT signaling R-HSA-1257604
PTEN Regulation R-HSA-6807070
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Gene expression (Transcription) R-HSA-74160
Intracellular signaling by second messengers R-HSA-9006925
Metabolism R-HSA-1430728
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MECP2 regulates transcription factors R-HSA-9022707
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of lipids R-HSA-556833
Signal Transduction R-HSA-162582
PPARA activates gene expression R-HSA-1989781
PTEN Regulation R-HSA-6807070
Developmental Biology R-HSA-1266738
Regulation of PTEN gene transcription R-HSA-8943724
Metabolism of proteins R-HSA-392499
Nuclear Receptor transcription pathway R-HSA-383280
Regulation of lipid metabolism by PPARalpha R-HSA-400206
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
Gene expression (Transcription) R-HSA-74160
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Generic Transcription Pathway R-HSA-212436
Metabolism R-HSA-1430728
Intracellular signaling by second messengers R-HSA-9006925
MECP2 regulates transcription factors R-HSA-9022707
Transcriptional Regulation by MECP2 R-HSA-8986944
SUMOylation of intracellular receptors R-HSA-4090294
RNA Polymerase II Transcription R-HSA-73857

Expression Atlas ENSG00000132170
NCBI gene (formerly Entrezgene) 5468
GeneCards 9236
HGNC Symbol HGNC:9236
MIM gene 601487
MIM morbid 609338
UniProtKB Gene Name Q6L9M1
WikiGene 5468
Gene: NFKB1
Ensembl ID : ENSG00000109320
Description: nuclear factor kappa B subunit 1
Gene Synonyms: KBF1,NF-KAPPAB,NF-KB1,NFKAPPAB,NFKB-P50,P105,P50
1 APIs:
204 Possible Orthologues:

SARS-CoV-1 Infection R-HSA-9678108
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
HCMV Early Events R-HSA-9609690
CLEC7A (Dectin-1) signaling R-HSA-5607764
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Disease R-HSA-1643685
Developmental Biology R-HSA-1266738
Signaling by Interleukins R-HSA-449147
TRAF6 mediated NF-kB activation R-HSA-933542
Activation of NF-kappaB in B cells R-HSA-1169091
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
C-type lectin receptors (CLRs) R-HSA-5621481
p75 NTR receptor-mediated signalling R-HSA-193704
Immune System R-HSA-168256
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
Signal Transduction R-HSA-162582
Generic Transcription Pathway R-HSA-212436
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Diseases of Immune System R-HSA-5260271
SARS-CoV Infections R-HSA-9679506
PKMTs methylate histone lysines R-HSA-3214841
Cell recruitment (pro-inflammatory response) R-HSA-9664424
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Regulated proteolysis of p75NTR R-HSA-193692
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Interleukin-17 signaling R-HSA-448424
Cellular responses to stress R-HSA-2262752
p75NTR signals via NF-kB R-HSA-193639
Innate Immune System R-HSA-168249
MyD88 dependent cascade initiated on endosome R-HSA-975155
IkBA variant leads to EDA-ID R-HSA-5603029
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Cellular Senescence R-HSA-2559583
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Interleukin-1 family signaling R-HSA-446652
Gene expression (Transcription) R-HSA-74160
Downstream TCR signaling R-HSA-202424
Interleukin-1 processing R-HSA-448706
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP kinase activation R-HSA-450294
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Death Receptor Signaling R-HSA-73887
Transcriptional Regulation by VENTX R-HSA-8853884
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Inflammasomes R-HSA-622312
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin organization R-HSA-4839726
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
HCMV Infection R-HSA-9609646
Infectious disease R-HSA-5663205
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
CLEC7A/inflammasome pathway R-HSA-5660668
Leishmania infection R-HSA-9658195
CD209 (DC-SIGN) signaling R-HSA-5621575
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Diseases associated with the TLR signaling cascade R-HSA-5602358
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Neutrophil degranulation R-HSA-6798695
SARS-CoV-1-host interactions R-HSA-9692914
TCR signaling R-HSA-202403
Chromatin modifying enzymes R-HSA-3247509
The NLRP3 inflammasome R-HSA-844456
MyD88-independent TLR4 cascade R-HSA-166166
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Interleukin-1 signaling R-HSA-9020702
Toll-like Receptor Cascades R-HSA-168898
SARS-CoV-1 Infection R-HSA-9678108
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cellular responses to stress R-HSA-2262752
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Neutrophil degranulation R-HSA-6798695
Leishmania infection R-HSA-9658195
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Gene expression (Transcription) R-HSA-74160
Diseases of Immune System R-HSA-5260271
p75NTR signals via NF-kB R-HSA-193639
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Signaling by Interleukins R-HSA-449147
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cellular Senescence R-HSA-2559583
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
PKMTs methylate histone lysines R-HSA-3214841
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Chromatin organization R-HSA-4839726
Infectious disease R-HSA-5663205
Interleukin-17 signaling R-HSA-448424
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-1 family signaling R-HSA-446652
Adaptive Immune System R-HSA-1280218
TRAF6 mediated NF-kB activation R-HSA-933542
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Immune System R-HSA-168256
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Chromatin modifying enzymes R-HSA-3247509
NF-kB is activated and signals survival R-HSA-209560
HCMV Early Events R-HSA-9609690
Interleukin-1 processing R-HSA-448706
HCMV Infection R-HSA-9609646
FCERI mediated NF-kB activation R-HSA-2871837
CLEC7A (Dectin-1) signaling R-HSA-5607764
Inflammasomes R-HSA-622312
CLEC7A/inflammasome pathway R-HSA-5660668
Generic Transcription Pathway R-HSA-212436
p75 NTR receptor-mediated signalling R-HSA-193704
Transcriptional Regulation by VENTX R-HSA-8853884
Downstream TCR signaling R-HSA-202424
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88-independent TLR4 cascade R-HSA-166166
Cell recruitment (pro-inflammatory response) R-HSA-9664424
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Signal Transduction R-HSA-162582
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
SARS-CoV-1-host interactions R-HSA-9692914
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
The NLRP3 inflammasome R-HSA-844456
Regulated proteolysis of p75NTR R-HSA-193692
MyD88 dependent cascade initiated on endosome R-HSA-975155
IkBA variant leads to EDA-ID R-HSA-5603029
Activation of NF-kappaB in B cells R-HSA-1169091
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Death Receptor Signaling R-HSA-73887
Diseases associated with the TLR signaling cascade R-HSA-5602358
TCR signaling R-HSA-202403
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RNA Polymerase II Transcription R-HSA-73857
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
SARS-CoV Infections R-HSA-9679506
MAP kinase activation R-HSA-450294
Neutrophil degranulation R-HSA-6798695
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Immune System R-HSA-168256
Infectious disease R-HSA-5663205
TCR signaling R-HSA-202403
MyD88 cascade initiated on plasma membrane R-HSA-975871
MAP kinase activation R-HSA-450294
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Generic Transcription Pathway R-HSA-212436
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-1 processing R-HSA-448706
CLEC7A/inflammasome pathway R-HSA-5660668
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
PKMTs methylate histone lysines R-HSA-3214841
p75 NTR receptor-mediated signalling R-HSA-193704
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
NF-kB is activated and signals survival R-HSA-209560
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Downstream TCR signaling R-HSA-202424
Chromatin modifying enzymes R-HSA-3247509
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
The NLRP3 inflammasome R-HSA-844456
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Activation of NF-kappaB in B cells R-HSA-1169091
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
C-type lectin receptors (CLRs) R-HSA-5621481
Transcriptional Regulation by VENTX R-HSA-8853884
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Purinergic signaling in leishmaniasis infection R-HSA-9660826
CLEC7A (Dectin-1) signaling R-HSA-5607764
FCERI mediated NF-kB activation R-HSA-2871837
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Death Receptor Signaling R-HSA-73887
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Regulated proteolysis of p75NTR R-HSA-193692
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
HCMV Infection R-HSA-9609646
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Innate Immune System R-HSA-168249
Adaptive Immune System R-HSA-1280218
TRAF6 mediated NF-kB activation R-HSA-933542
Leishmania infection R-HSA-9658195
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular responses to stimuli R-HSA-8953897
Inflammasomes R-HSA-622312
Gene expression (Transcription) R-HSA-74160
Toll-like Receptor Cascades R-HSA-168898
p75NTR signals via NF-kB R-HSA-193639
Signaling by Interleukins R-HSA-449147
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-17 signaling R-HSA-448424
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Chromatin organization R-HSA-4839726
Interleukin-1 signaling R-HSA-9020702
HCMV Early Events R-HSA-9609690
Diseases associated with the TLR signaling cascade R-HSA-5602358
IkBA variant leads to EDA-ID R-HSA-5603029
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV Infections R-HSA-9679506
RNA Polymerase II Transcription R-HSA-73857
Cellular Senescence R-HSA-2559583
Diseases of Immune System R-HSA-5260271
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
SARS-CoV-1 Infection R-HSA-9678108
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
MyD88 dependent cascade initiated on endosome R-HSA-975155
Diseases associated with the TLR signaling cascade R-HSA-5602358
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SARS-CoV-1-host interactions R-HSA-9692914
Interleukin-17 signaling R-HSA-448424
Interleukin-1 processing R-HSA-448706
Inflammasomes R-HSA-622312
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
FCERI mediated NF-kB activation R-HSA-2871837
p75NTR signals via NF-kB R-HSA-193639
Cellular responses to stimuli R-HSA-8953897
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Diseases of Immune System R-HSA-5260271
Regulated proteolysis of p75NTR R-HSA-193692
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 family signaling R-HSA-446652
Innate Immune System R-HSA-168249
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Cellular responses to stress R-HSA-2262752
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Interleukin-1 signaling R-HSA-9020702
Downstream TCR signaling R-HSA-202424
IkBA variant leads to EDA-ID R-HSA-5603029
SARS-CoV Infections R-HSA-9679506
Activation of NF-kappaB in B cells R-HSA-1169091
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
HCMV Early Events R-HSA-9609690
Leishmania infection R-HSA-9658195
Chromatin organization R-HSA-4839726
PKMTs methylate histone lysines R-HSA-3214841
Neutrophil degranulation R-HSA-6798695
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
SARS-CoV-1 Infection R-HSA-9678108
TRAF6 mediated NF-kB activation R-HSA-933542
Transcriptional Regulation by VENTX R-HSA-8853884
TCR signaling R-HSA-202403
Cellular Senescence R-HSA-2559583
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Chromatin modifying enzymes R-HSA-3247509
Signaling by Interleukins R-HSA-449147
MyD88 cascade initiated on plasma membrane R-HSA-975871
Generic Transcription Pathway R-HSA-212436
Cytokine Signaling in Immune system R-HSA-1280215
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP kinase activation R-HSA-450294
MyD88 dependent cascade initiated on endosome R-HSA-975155
CLEC7A/inflammasome pathway R-HSA-5660668
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Death Receptor Signaling R-HSA-73887
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Infectious disease R-HSA-5663205
HCMV Infection R-HSA-9609646
Toll-like Receptor Cascades R-HSA-168898
CD209 (DC-SIGN) signaling R-HSA-5621575
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Disease R-HSA-1643685
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Developmental Biology R-HSA-1266738
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
NF-kB is activated and signals survival R-HSA-209560
Gene expression (Transcription) R-HSA-74160
The NLRP3 inflammasome R-HSA-844456
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Adaptive Immune System R-HSA-1280218
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
RNA Polymerase II Transcription R-HSA-73857
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
The NLRP3 inflammasome R-HSA-844456
Cellular responses to stimuli R-HSA-8953897
Gene expression (Transcription) R-HSA-74160
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAF6 mediated NF-kB activation R-HSA-933542
Neutrophil degranulation R-HSA-6798695
Developmental Biology R-HSA-1266738
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
SARS-CoV-1-host interactions R-HSA-9692914
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Adaptive Immune System R-HSA-1280218
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TCR signaling R-HSA-202403
PKMTs methylate histone lysines R-HSA-3214841
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Generic Transcription Pathway R-HSA-212436
p75NTR signals via NF-kB R-HSA-193639
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MAP kinase activation R-HSA-450294
Diseases associated with the TLR signaling cascade R-HSA-5602358
MyD88-independent TLR4 cascade R-HSA-166166
Cellular responses to stress R-HSA-2262752
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
p75 NTR receptor-mediated signalling R-HSA-193704
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
IkBA variant leads to EDA-ID R-HSA-5603029
FCERI mediated NF-kB activation R-HSA-2871837
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RNA Polymerase II Transcription R-HSA-73857
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Innate Immune System R-HSA-168249
Downstream TCR signaling R-HSA-202424
MyD88 cascade initiated on plasma membrane R-HSA-975871
Chromatin modifying enzymes R-HSA-3247509
Inflammasomes R-HSA-622312
Death Receptor Signaling R-HSA-73887
Leishmania infection R-HSA-9658195
SARS-CoV-1 Infection R-HSA-9678108
Disease R-HSA-1643685
Interleukin-17 signaling R-HSA-448424
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Regulated proteolysis of p75NTR R-HSA-193692
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
Purinergic signaling in leishmaniasis infection R-HSA-9660826
CLEC7A/inflammasome pathway R-HSA-5660668
HCMV Infection R-HSA-9609646
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Diseases of Immune System R-HSA-5260271
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Interleukin-1 family signaling R-HSA-446652
Chromatin organization R-HSA-4839726
Infectious disease R-HSA-5663205
Signaling by Interleukins R-HSA-449147
Cellular Senescence R-HSA-2559583
Activation of NF-kappaB in B cells R-HSA-1169091
SARS-CoV Infections R-HSA-9679506
Cytokine Signaling in Immune system R-HSA-1280215
CD209 (DC-SIGN) signaling R-HSA-5621575
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
HCMV Early Events R-HSA-9609690
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
C-type lectin receptors (CLRs) R-HSA-5621481
Cell recruitment (pro-inflammatory response) R-HSA-9664424
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Transcriptional Regulation by VENTX R-HSA-8853884
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Interleukin-1 processing R-HSA-448706
RNA Polymerase II Transcription R-HSA-73857
Diseases associated with the TLR signaling cascade R-HSA-5602358
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Interleukin-17 signaling R-HSA-448424
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Interleukin-1 signaling R-HSA-9020702
Cellular Senescence R-HSA-2559583
Gene expression (Transcription) R-HSA-74160
Generic Transcription Pathway R-HSA-212436
Disease R-HSA-1643685
Adaptive Immune System R-HSA-1280218
MyD88-independent TLR4 cascade R-HSA-166166
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Death Receptor Signaling R-HSA-73887
Interleukin-1 family signaling R-HSA-446652
SARS-CoV-1-host interactions R-HSA-9692914
Cellular responses to stress R-HSA-2262752
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Developmental Biology R-HSA-1266738
Cytokine Signaling in Immune system R-HSA-1280215
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Downstream TCR signaling R-HSA-202424
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Signaling by Interleukins R-HSA-449147
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
HCMV Early Events R-HSA-9609690
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
IkBA variant leads to EDA-ID R-HSA-5603029
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Inflammasomes R-HSA-622312
CLEC7A/inflammasome pathway R-HSA-5660668
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FCERI mediated NF-kB activation R-HSA-2871837
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll-like Receptor Cascades R-HSA-168898
NF-kB is activated and signals survival R-HSA-209560
The NLRP3 inflammasome R-HSA-844456
TCR signaling R-HSA-202403
Transcriptional Regulation by VENTX R-HSA-8853884
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Signal Transduction R-HSA-162582
CLEC7A (Dectin-1) signaling R-HSA-5607764
CD209 (DC-SIGN) signaling R-HSA-5621575
PKMTs methylate histone lysines R-HSA-3214841
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Leishmania infection R-HSA-9658195
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MAP kinase activation R-HSA-450294
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
SARS-CoV Infections R-HSA-9679506
Regulated proteolysis of p75NTR R-HSA-193692
Infectious disease R-HSA-5663205
p75NTR signals via NF-kB R-HSA-193639
TRAF6 mediated NF-kB activation R-HSA-933542
MyD88 cascade initiated on plasma membrane R-HSA-975871
SARS-CoV-1 Infection R-HSA-9678108
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Chromatin organization R-HSA-4839726
Interleukin-1 processing R-HSA-448706
Neutrophil degranulation R-HSA-6798695
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
C-type lectin receptors (CLRs) R-HSA-5621481
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cellular responses to stimuli R-HSA-8953897
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
HCMV Infection R-HSA-9609646
p75 NTR receptor-mediated signalling R-HSA-193704
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin modifying enzymes R-HSA-3247509
Diseases of Immune System R-HSA-5260271
Infectious disease R-HSA-5663205
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
CLEC7A/inflammasome pathway R-HSA-5660668
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
RNA Polymerase II Transcription R-HSA-73857
Cytokine Signaling in Immune system R-HSA-1280215
Purinergic signaling in leishmaniasis infection R-HSA-9660826
MyD88-independent TLR4 cascade R-HSA-166166
Immune System R-HSA-168256
Cellular Senescence R-HSA-2559583
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Chromatin organization R-HSA-4839726
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
SARS-CoV-1 Infection R-HSA-9678108
C-type lectin receptors (CLRs) R-HSA-5621481
Interleukin-1 processing R-HSA-448706
Innate Immune System R-HSA-168249
Inflammasomes R-HSA-622312
Generic Transcription Pathway R-HSA-212436
p75 NTR receptor-mediated signalling R-HSA-193704
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 signaling R-HSA-9020702
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
SARS-CoV Infections R-HSA-9679506
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Disease R-HSA-1643685
CD209 (DC-SIGN) signaling R-HSA-5621575
Cellular responses to stress R-HSA-2262752
Regulated proteolysis of p75NTR R-HSA-193692
Chromatin modifying enzymes R-HSA-3247509
Leishmania infection R-HSA-9658195
Diseases associated with the TLR signaling cascade R-HSA-5602358
MAP kinase activation R-HSA-450294
Adaptive Immune System R-HSA-1280218
IkBA variant leads to EDA-ID R-HSA-5603029
Developmental Biology R-HSA-1266738
Death Receptor Signaling R-HSA-73887
p75NTR signals via NF-kB R-HSA-193639
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Downstream TCR signaling R-HSA-202424
Activation of NF-kappaB in B cells R-HSA-1169091
Diseases of Immune System R-HSA-5260271
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PKMTs methylate histone lysines R-HSA-3214841
SARS-CoV-1-host interactions R-HSA-9692914
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
The NLRP3 inflammasome R-HSA-844456
HCMV Early Events R-HSA-9609690
Signaling by Interleukins R-HSA-449147
TCR signaling R-HSA-202403
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Transcriptional Regulation by VENTX R-HSA-8853884
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Toll-like Receptor Cascades R-HSA-168898
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
NF-kB is activated and signals survival R-HSA-209560
Gene expression (Transcription) R-HSA-74160
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
Cell recruitment (pro-inflammatory response) R-HSA-9664424
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAF6 mediated NF-kB activation R-HSA-933542
Cellular responses to stimuli R-HSA-8953897
HCMV Infection R-HSA-9609646
Neutrophil degranulation R-HSA-6798695
Interleukin-17 signaling R-HSA-448424
Interleukin-1 family signaling R-HSA-446652
Signal Transduction R-HSA-162582
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
MyD88 cascade initiated on plasma membrane R-HSA-975871
FCERI mediated NF-kB activation R-HSA-2871837
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
HCMV Early Events R-HSA-9609690
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Transcriptional Regulation by VENTX R-HSA-8853884
Inflammasomes R-HSA-622312
Innate Immune System R-HSA-168249
Generic Transcription Pathway R-HSA-212436
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 processing R-HSA-448706
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Immune System R-HSA-168256
Cytokine Signaling in Immune system R-HSA-1280215
Gene expression (Transcription) R-HSA-74160
Activation of NF-kappaB in B cells R-HSA-1169091
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
Neutrophil degranulation R-HSA-6798695
Diseases associated with the TLR signaling cascade R-HSA-5602358
TCR signaling R-HSA-202403
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
HCMV Infection R-HSA-9609646
NF-kB is activated and signals survival R-HSA-209560
Toll-like Receptor Cascades R-HSA-168898
p75NTR signals via NF-kB R-HSA-193639
Infectious disease R-HSA-5663205
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Downstream TCR signaling R-HSA-202424
SARS-CoV-1 Infection R-HSA-9678108
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Adaptive Immune System R-HSA-1280218
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Chromatin organization R-HSA-4839726
Developmental Biology R-HSA-1266738
RNA Polymerase II Transcription R-HSA-73857
FCERI mediated NF-kB activation R-HSA-2871837
SARS-CoV Infections R-HSA-9679506
Signal Transduction R-HSA-162582
Diseases of Immune System R-HSA-5260271
SARS-CoV-1-host interactions R-HSA-9692914
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
TRAF6 mediated NF-kB activation R-HSA-933542
MAP kinase activation R-HSA-450294
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stimuli R-HSA-8953897
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88 cascade initiated on plasma membrane R-HSA-975871
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Regulated proteolysis of p75NTR R-HSA-193692
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
C-type lectin receptors (CLRs) R-HSA-5621481
CD209 (DC-SIGN) signaling R-HSA-5621575
Signaling by Interleukins R-HSA-449147
Chromatin modifying enzymes R-HSA-3247509
Leishmania infection R-HSA-9658195
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Death Receptor Signaling R-HSA-73887
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
Cellular responses to stress R-HSA-2262752
MyD88-independent TLR4 cascade R-HSA-166166
Cell recruitment (pro-inflammatory response) R-HSA-9664424
p75 NTR receptor-mediated signalling R-HSA-193704
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-17 signaling R-HSA-448424
CLEC7A/inflammasome pathway R-HSA-5660668
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
The NLRP3 inflammasome R-HSA-844456
PKMTs methylate histone lysines R-HSA-3214841
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cellular Senescence R-HSA-2559583
Disease R-HSA-1643685
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Interleukin-1 family signaling R-HSA-446652
Interleukin-1 signaling R-HSA-9020702
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll-like Receptor Cascades R-HSA-168898
SARS-CoV-1 Infection R-HSA-9678108
Purinergic signaling in leishmaniasis infection R-HSA-9660826
MyD88 cascade initiated on plasma membrane R-HSA-975871
Leishmania infection R-HSA-9658195
IkBA variant leads to EDA-ID R-HSA-5603029
p75 NTR receptor-mediated signalling R-HSA-193704
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
SARS-CoV Infections R-HSA-9679506
Disease R-HSA-1643685
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 processing R-HSA-448706
HCMV Infection R-HSA-9609646
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Cellular responses to stress R-HSA-2262752
MyD88 dependent cascade initiated on endosome R-HSA-975155
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Interleukin-17 signaling R-HSA-448424
CLEC7A/inflammasome pathway R-HSA-5660668
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Transcriptional regulation of white adipocyte differentiation R-HSA-381340
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Chromatin modifying enzymes R-HSA-3247509
PKMTs methylate histone lysines R-HSA-3214841
Death Receptor Signaling R-HSA-73887
CD209 (DC-SIGN) signaling R-HSA-5621575
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
Adaptive Immune System R-HSA-1280218
Inflammasomes R-HSA-622312
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Cytokine Signaling in Immune system R-HSA-1280215
Chromatin organization R-HSA-4839726
Neutrophil degranulation R-HSA-6798695
Developmental Biology R-HSA-1266738
The NLRP3 inflammasome R-HSA-844456
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Gene expression (Transcription) R-HSA-74160
CLEC7A (Dectin-1) signaling R-HSA-5607764
MAP kinase activation R-HSA-450294
Downstream TCR signaling R-HSA-202424
TRAF6 mediated NF-kB activation R-HSA-933542
p75NTR signals via NF-kB R-HSA-193639
Interleukin-1 signaling R-HSA-9020702
RNA Polymerase II Transcription R-HSA-73857
Cell recruitment (pro-inflammatory response) R-HSA-9664424
NF-kB is activated and signals survival R-HSA-209560
Cellular Senescence R-HSA-2559583
Signaling by Interleukins R-HSA-449147
Interleukin-1 family signaling R-HSA-446652
FCERI mediated NF-kB activation R-HSA-2871837
Infectious disease R-HSA-5663205
SARS-CoV-1-host interactions R-HSA-9692914
TCR signaling R-HSA-202403
C-type lectin receptors (CLRs) R-HSA-5621481
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Transcriptional Regulation by VENTX R-HSA-8853884
HCMV Early Events R-HSA-9609690
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916
Regulated proteolysis of p75NTR R-HSA-193692
Activation of NF-kappaB in B cells R-HSA-1169091
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Diseases of Immune System R-HSA-5260271
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Generic Transcription Pathway R-HSA-212436
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Diseases associated with the TLR signaling cascade R-HSA-5602358
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061

Expression Atlas ENSG00000109320
LRG display in Ensembl gene LRG_1316
NCBI gene (formerly Entrezgene) 4790
GeneCards 7794
HGNC Symbol HGNC:7794
MIM gene 164011
MIM morbid 616576
UniProtKB Gene Name P19838
WikiGene 4790
Gene: MDM2
Ensembl ID : ENSG00000135679
Description: MDM2 proto-oncogene
Gene Synonyms: HDM2,MGC5370
3 APIs:
257 Possible Orthologues:

SUMOylation R-HSA-2990846
Regulation of TP53 Activity through Methylation R-HSA-6804760
Transcriptional Regulation by TP53 R-HSA-3700989
Oxidative Stress Induced Senescence R-HSA-2559580
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
Disease R-HSA-1643685
Neuronal System R-HSA-112316
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Regulation of RUNX3 expression and activity R-HSA-8941858
Stabilization of p53 R-HSA-69541
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Regulation of TP53 Expression and Degradation R-HSA-6806003
Oncogene Induced Senescence R-HSA-2559585
PI3K/AKT Signaling in Cancer R-HSA-2219528
Metabolism of proteins R-HSA-392499
RNA Polymerase II Transcription R-HSA-73857
Trafficking of AMPA receptors R-HSA-399719
Regulation of TP53 Activity R-HSA-5633007
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional Regulation by NPAS4 R-HSA-9634815
p53-Dependent G1 DNA Damage Response R-HSA-69563
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Gene expression (Transcription) R-HSA-74160
G1/S DNA Damage Checkpoints R-HSA-69615
Cell Cycle Checkpoints R-HSA-69620
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Generic Transcription Pathway R-HSA-212436
Cellular Senescence R-HSA-2559583
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NPAS4 regulates expression of target genes R-HSA-9768919
Cell Cycle R-HSA-1640170
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Signal Transduction R-HSA-162582
Deubiquitination R-HSA-5688426
SUMOylation of transcription factors R-HSA-3232118
Transmission across Chemical Synapses R-HSA-112315
Regulation of TP53 Degradation R-HSA-6804757
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Intracellular signaling by second messengers R-HSA-9006925
Cellular responses to stress R-HSA-2262752
AKT phosphorylates targets in the cytosol R-HSA-198323
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular Senescence R-HSA-2559583
SUMOylation R-HSA-2990846
RNA Polymerase II Transcription R-HSA-73857
Regulation of RUNX3 expression and activity R-HSA-8941858
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Metabolism of proteins R-HSA-392499
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Generic Transcription Pathway R-HSA-212436
SUMOylation of transcription factors R-HSA-3232118
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of TP53 Activity R-HSA-5633007
Cellular responses to stimuli R-HSA-8953897
p53-Dependent G1 DNA Damage Response R-HSA-69563
PIP3 activates AKT signaling R-HSA-1257604
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Expression and Degradation R-HSA-6806003
Transcriptional Regulation by NPAS4 R-HSA-9634815
Transcriptional Regulation by TP53 R-HSA-3700989
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
G1/S DNA Damage Checkpoints R-HSA-69615
Oxidative Stress Induced Senescence R-HSA-2559580
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
NPAS4 regulates expression of target genes R-HSA-9768919
Cell Cycle Checkpoints R-HSA-69620
Gene expression (Transcription) R-HSA-74160
Stabilization of p53 R-HSA-69541
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Neuronal System R-HSA-112316
Transmission across Chemical Synapses R-HSA-112315
Intracellular signaling by second messengers R-HSA-9006925
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Degradation R-HSA-6804757
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the cytosol R-HSA-198323
Oncogene Induced Senescence R-HSA-2559585
Cellular responses to stress R-HSA-2262752
Transcriptional regulation by RUNX3 R-HSA-8878159
Transcriptional regulation by RUNX3 R-HSA-8878159
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular responses to stress R-HSA-2262752
Intracellular signaling by second messengers R-HSA-9006925
NPAS4 regulates expression of target genes R-HSA-9768919
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Neuronal System R-HSA-112316
Deubiquitination R-HSA-5688426
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Transmission across Chemical Synapses R-HSA-112315
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the cytosol R-HSA-198323
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of TP53 Activity R-HSA-5633007
Regulation of TP53 Degradation R-HSA-6804757
Oxidative Stress Induced Senescence R-HSA-2559580
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMOylation of transcription factors R-HSA-3232118
Generic Transcription Pathway R-HSA-212436
Transcriptional Regulation by NPAS4 R-HSA-9634815
SUMOylation R-HSA-2990846
Cellular responses to stimuli R-HSA-8953897
Metabolism of proteins R-HSA-392499
Stabilization of p53 R-HSA-69541
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Dependent G1 DNA Damage Response R-HSA-69563
Gene expression (Transcription) R-HSA-74160
RNA Polymerase II Transcription R-HSA-73857
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
Trafficking of AMPA receptors R-HSA-399719
Signal Transduction R-HSA-162582
Post-translational protein modification R-HSA-597592
Cellular Senescence R-HSA-2559583
PI3K/AKT Signaling in Cancer R-HSA-2219528
G1/S DNA Damage Checkpoints R-HSA-69615
PIP3 activates AKT signaling R-HSA-1257604
Cell Cycle Checkpoints R-HSA-69620
Oncogene Induced Senescence R-HSA-2559585
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
AKT phosphorylates targets in the cytosol R-HSA-198323
Transcriptional Regulation by NPAS4 R-HSA-9634815
Trafficking of AMPA receptors R-HSA-399719
Gene expression (Transcription) R-HSA-74160
Metabolism of proteins R-HSA-392499
Regulation of TP53 Degradation R-HSA-6804757
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional Regulation by TP53 R-HSA-3700989
Transmission across Chemical Synapses R-HSA-112315
Cellular responses to stress R-HSA-2262752
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of TP53 Expression and Degradation R-HSA-6806003
RNA Polymerase II Transcription R-HSA-73857
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX3 expression and activity R-HSA-8941858
SUMOylation of transcription factors R-HSA-3232118
Cellular responses to stimuli R-HSA-8953897
Oxidative Stress Induced Senescence R-HSA-2559580
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Signal Transduction R-HSA-162582
Stabilization of p53 R-HSA-69541
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
PI3K/AKT Signaling in Cancer R-HSA-2219528
G1/S DNA Damage Checkpoints R-HSA-69615
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Post-translational protein modification R-HSA-597592
Regulation of TP53 Activity through Methylation R-HSA-6804760
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Deubiquitination R-HSA-5688426
p53-Dependent G1 DNA Damage Response R-HSA-69563
SUMOylation R-HSA-2990846
Oncogene Induced Senescence R-HSA-2559585
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Cell Cycle R-HSA-1640170
Ub-specific processing proteases R-HSA-5689880
Intracellular signaling by second messengers R-HSA-9006925
Cellular Senescence R-HSA-2559583
Neuronal System R-HSA-112316
NPAS4 regulates expression of target genes R-HSA-9768919
Regulation of TP53 Activity R-HSA-5633007
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Disease R-HSA-1643685
AKT phosphorylates targets in the cytosol R-HSA-198323
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transcriptional Regulation by NPAS4 R-HSA-9634815
Oncogene Induced Senescence R-HSA-2559585
Post-translational protein modification R-HSA-597592
Cellular responses to stress R-HSA-2262752
Transcriptional Regulation by TP53 R-HSA-3700989
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Signal Transduction R-HSA-162582
Trafficking of AMPA receptors R-HSA-399719
Cell Cycle R-HSA-1640170
Disease R-HSA-1643685
Regulation of TP53 Activity through Methylation R-HSA-6804760
Regulation of RUNX3 expression and activity R-HSA-8941858
Transmission across Chemical Synapses R-HSA-112315
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Stabilization of p53 R-HSA-69541
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SUMOylation R-HSA-2990846
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle Checkpoints R-HSA-69620
Neuronal System R-HSA-112316
SUMOylation of transcription factors R-HSA-3232118
Ub-specific processing proteases R-HSA-5689880
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
Intracellular signaling by second messengers R-HSA-9006925
Oxidative Stress Induced Senescence R-HSA-2559580
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
PI3K/AKT Signaling in Cancer R-HSA-2219528
NPAS4 regulates expression of target genes R-HSA-9768919
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Metabolism of proteins R-HSA-392499
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
G1/S DNA Damage Checkpoints R-HSA-69615
Cellular Senescence R-HSA-2559583
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of TP53 Degradation R-HSA-6804757
Transcriptional Regulation by TP53 R-HSA-3700989
Cell Cycle R-HSA-1640170
Trafficking of AMPA receptors R-HSA-399719
Transcriptional Regulation by NPAS4 R-HSA-9634815
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Cellular Senescence R-HSA-2559583
Stabilization of p53 R-HSA-69541
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
PI3K/AKT Signaling in Cancer R-HSA-2219528
AKT phosphorylates targets in the cytosol R-HSA-198323
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ub-specific processing proteases R-HSA-5689880
Cellular responses to stress R-HSA-2262752
Neuronal System R-HSA-112316
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Regulation of TP53 Activity through Methylation R-HSA-6804760
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PIP3 activates AKT signaling R-HSA-1257604
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
SUMOylation R-HSA-2990846
Disease R-HSA-1643685
Transcriptional regulation by RUNX3 R-HSA-8878159
RNA Polymerase II Transcription R-HSA-73857
NPAS4 regulates expression of target genes R-HSA-9768919
Oncogene Induced Senescence R-HSA-2559585
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
G1/S DNA Damage Checkpoints R-HSA-69615
Transmission across Chemical Synapses R-HSA-112315
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Oxidative Stress Induced Senescence R-HSA-2559580
Deubiquitination R-HSA-5688426
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity R-HSA-5633007
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
SUMOylation of transcription factors R-HSA-3232118
NPAS4 regulates expression of target genes R-HSA-9768919
PIP3 activates AKT signaling R-HSA-1257604
Metabolism of proteins R-HSA-392499
Regulation of TP53 Activity through Methylation R-HSA-6804760
Transmission across Chemical Synapses R-HSA-112315
Transcriptional Regulation by NPAS4 R-HSA-9634815
RNA Polymerase II Transcription R-HSA-73857
SUMOylation R-HSA-2990846
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Degradation R-HSA-6804757
PI3K/AKT Signaling in Cancer R-HSA-2219528
Neuronal System R-HSA-112316
Disease R-HSA-1643685
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
SUMOylation of transcription factors R-HSA-3232118
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Oxidative Stress Induced Senescence R-HSA-2559580
Stabilization of p53 R-HSA-69541
Regulation of TP53 Expression and Degradation R-HSA-6806003
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Regulation of TP53 Activity R-HSA-5633007
Trafficking of AMPA receptors R-HSA-399719
Oncogene Induced Senescence R-HSA-2559585
Cellular responses to stress R-HSA-2262752
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
Transcriptional Regulation by TP53 R-HSA-3700989
Deubiquitination R-HSA-5688426
G1/S DNA Damage Checkpoints R-HSA-69615
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Cell Cycle R-HSA-1640170
AKT phosphorylates targets in the cytosol R-HSA-198323
Intracellular signaling by second messengers R-HSA-9006925
Post-translational protein modification R-HSA-597592
Generic Transcription Pathway R-HSA-212436
Transcriptional regulation by RUNX3 R-HSA-8878159
Ub-specific processing proteases R-HSA-5689880
Cellular Senescence R-HSA-2559583
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Signal Transduction R-HSA-162582
Cellular responses to stimuli R-HSA-8953897
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Transcriptional regulation by RUNX3 R-HSA-8878159
Neuronal System R-HSA-112316
Generic Transcription Pathway R-HSA-212436
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Regulation of RUNX3 expression and activity R-HSA-8941858
Metabolism of proteins R-HSA-392499
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
NPAS4 regulates expression of target genes R-HSA-9768919
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transmission across Chemical Synapses R-HSA-112315
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
p53-Dependent G1 DNA Damage Response R-HSA-69563
Stabilization of p53 R-HSA-69541
Post-translational protein modification R-HSA-597592
G1/S DNA Damage Checkpoints R-HSA-69615
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Disease R-HSA-1643685
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Regulation of TP53 Activity R-HSA-5633007
Deubiquitination R-HSA-5688426
AKT phosphorylates targets in the cytosol R-HSA-198323
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
SUMOylation R-HSA-2990846
Ub-specific processing proteases R-HSA-5689880
Regulation of TP53 Activity through Methylation R-HSA-6804760
PIP3 activates AKT signaling R-HSA-1257604
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Oxidative Stress Induced Senescence R-HSA-2559580
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
SUMOylation of transcription factors R-HSA-3232118
Oncogene Induced Senescence R-HSA-2559585
Regulation of TP53 Expression and Degradation R-HSA-6806003
Cell Cycle Checkpoints R-HSA-69620
Cellular Senescence R-HSA-2559583
Regulation of TP53 Degradation R-HSA-6804757
Transcriptional Regulation by TP53 R-HSA-3700989
Trafficking of AMPA receptors R-HSA-399719
Intracellular signaling by second messengers R-HSA-9006925
RNA Polymerase II Transcription R-HSA-73857
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
PI3K/AKT Signaling in Cancer R-HSA-2219528
Regulation of TP53 Activity R-HSA-5633007
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Trafficking of AMPA receptors R-HSA-399719
Stabilization of p53 R-HSA-69541
Transmission across Chemical Synapses R-HSA-112315
G1/S DNA Damage Checkpoints R-HSA-69615
Signal Transduction R-HSA-162582
Transcriptional Regulation by NPAS4 R-HSA-9634815
Regulation of RUNX3 expression and activity R-HSA-8941858
Cellular responses to stimuli R-HSA-8953897
Neuronal System R-HSA-112316
SUMOylation R-HSA-2990846
AKT phosphorylates targets in the cytosol R-HSA-198323
Regulation of TP53 Expression and Degradation R-HSA-6806003
Intracellular signaling by second messengers R-HSA-9006925
p53-Dependent G1 DNA Damage Response R-HSA-69563
Post-translational protein modification R-HSA-597592
PIP3 activates AKT signaling R-HSA-1257604
NPAS4 regulates expression of target genes R-HSA-9768919
PI3K/AKT Signaling in Cancer R-HSA-2219528
Ub-specific processing proteases R-HSA-5689880
Transcriptional Regulation by TP53 R-HSA-3700989
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
Disease R-HSA-1643685
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Activity through Methylation R-HSA-6804760
SUMOylation of transcription factors R-HSA-3232118
Metabolism of proteins R-HSA-392499
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Regulation of TP53 Degradation R-HSA-6804757
Cell Cycle R-HSA-1640170
Oncogene Induced Senescence R-HSA-2559585
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Cellular responses to stress R-HSA-2262752
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Oxidative Stress Induced Senescence R-HSA-2559580
Cellular Senescence R-HSA-2559583
Deubiquitination R-HSA-5688426
Cell Cycle R-HSA-1640170
SUMOylation R-HSA-2990846
p53-Dependent G1 DNA Damage Response R-HSA-69563
Cellular responses to stress R-HSA-2262752
Transmission across Chemical Synapses R-HSA-112315
G1/S DNA Damage Checkpoints R-HSA-69615
Transcriptional Regulation by NPAS4 R-HSA-9634815
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400
Trafficking of AMPA receptors R-HSA-399719
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
AKT phosphorylates targets in the cytosol R-HSA-198323
Post-translational protein modification R-HSA-597592
Ub-specific processing proteases R-HSA-5689880
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional Regulation by TP53 R-HSA-3700989
SUMOylation of ubiquitinylation proteins R-HSA-3232142
Stabilization of p53 R-HSA-69541
Intracellular signaling by second messengers R-HSA-9006925
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cellular Senescence R-HSA-2559583
Oncogene Induced Senescence R-HSA-2559585
SUMOylation of transcription factors R-HSA-3232118
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Regulation of RUNX3 expression and activity R-HSA-8941858
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
Neuronal System R-HSA-112316
NPAS4 regulates expression of target genes R-HSA-9768919
Regulation of TP53 Expression and Degradation R-HSA-6806003
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signal Transduction R-HSA-162582
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756
Cellular responses to stimuli R-HSA-8953897
Regulation of TP53 Activity R-HSA-5633007
Transcriptional regulation by RUNX3 R-HSA-8878159
Oxidative Stress Induced Senescence R-HSA-2559580
Disease R-HSA-1643685
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721
Regulation of TP53 Degradation R-HSA-6804757
Regulation of TP53 Activity through Methylation R-HSA-6804760

Expression Atlas ENSG00000135679
NCBI gene (formerly Entrezgene) 4193
GeneCards 6973
HGNC Symbol HGNC:6973
MIM gene 164785
MIM morbid 618681
UniProtKB Gene Name Q9H4C5
WikiGene 4193
Gene: NFKB2
Ensembl ID : ENSG00000077150
Description: nuclear factor kappa B subunit 2
Gene Synonyms: LYT-10,NF-KB2,P105,P49/P100,P52
1 APIs:
124 Possible Orthologues:

MyD88 dependent cascade initiated on endosome R-HSA-975155
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Diseases of Immune System R-HSA-5260271
Interleukin-1 family signaling R-HSA-446652
Inflammasomes R-HSA-622312
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Infectious disease R-HSA-5663205
The NLRP3 inflammasome R-HSA-844456
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
CLEC7A (Dectin-1) signaling R-HSA-5607764
Post-translational protein modification R-HSA-597592
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
SUMOylation of immune response proteins R-HSA-4755510
TRAF6 mediated NF-kB activation R-HSA-933542
Diseases associated with the TLR signaling cascade R-HSA-5602358
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Chromatin modifying enzymes R-HSA-3247509
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
MyD88-independent TLR4 cascade R-HSA-166166
SUMOylation R-HSA-2990846
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
IkBA variant leads to EDA-ID R-HSA-5603029
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
PKMTs methylate histone lysines R-HSA-3214841
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll-like Receptor Cascades R-HSA-168898
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cell recruitment (pro-inflammatory response) R-HSA-9664424
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Interleukin-1 processing R-HSA-448706
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Purinergic signaling in leishmaniasis infection R-HSA-9660826
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Chromatin organization R-HSA-4839726
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Innate Immune System R-HSA-168249
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Leishmania infection R-HSA-9658195
SUMOylation of immune response proteins R-HSA-4755510
Infectious disease R-HSA-5663205
The NLRP3 inflammasome R-HSA-844456
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Immune System R-HSA-168256
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Post-translational protein modification R-HSA-597592
Chromatin organization R-HSA-4839726
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 signaling R-HSA-9020702
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
C-type lectin receptors (CLRs) R-HSA-5621481
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Chromatin modifying enzymes R-HSA-3247509
SUMOylation R-HSA-2990846
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRAF6 mediated NF-kB activation R-HSA-933542
Leishmania infection R-HSA-9658195
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Inflammasomes R-HSA-622312
Disease R-HSA-1643685
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 processing R-HSA-448706
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Innate Immune System R-HSA-168249
Signaling by Interleukins R-HSA-449147
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
MyD88 cascade initiated on plasma membrane R-HSA-975871
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Cytokine Signaling in Immune system R-HSA-1280215
Diseases associated with the TLR signaling cascade R-HSA-5602358
Diseases of Immune System R-HSA-5260271
IkBA variant leads to EDA-ID R-HSA-5603029
Metabolism of proteins R-HSA-392499
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
PKMTs methylate histone lysines R-HSA-3214841
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Metabolism of proteins R-HSA-392499
PKMTs methylate histone lysines R-HSA-3214841
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MyD88 cascade initiated on plasma membrane R-HSA-975871
Post-translational protein modification R-HSA-597592
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by Interleukins R-HSA-449147
The NLRP3 inflammasome R-HSA-844456
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Interleukin-1 signaling R-HSA-9020702
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll-like Receptor Cascades R-HSA-168898
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
SUMOylation R-HSA-2990846
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Disease R-HSA-1643685
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Infectious disease R-HSA-5663205
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
CLEC7A (Dectin-1) signaling R-HSA-5607764
Diseases of Immune System R-HSA-5260271
TRAF6 mediated NF-kB activation R-HSA-933542
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Chromatin organization R-HSA-4839726
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Immune System R-HSA-168256
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
SUMOylation of immune response proteins R-HSA-4755510
Inflammasomes R-HSA-622312
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Leishmania infection R-HSA-9658195
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Chromatin modifying enzymes R-HSA-3247509
Interleukin-1 processing R-HSA-448706
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Diseases associated with the TLR signaling cascade R-HSA-5602358
Cytokine Signaling in Immune system R-HSA-1280215
MyD88-independent TLR4 cascade R-HSA-166166
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
IkBA variant leads to EDA-ID R-HSA-5603029
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
SUMOylation R-HSA-2990846
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Diseases of Immune System R-HSA-5260271
Diseases associated with the TLR signaling cascade R-HSA-5602358
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
PKMTs methylate histone lysines R-HSA-3214841
Post-translational protein modification R-HSA-597592
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Signaling by Interleukins R-HSA-449147
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Chromatin modifying enzymes R-HSA-3247509
CLEC7A (Dectin-1) signaling R-HSA-5607764
The NLRP3 inflammasome R-HSA-844456
MyD88 cascade initiated on plasma membrane R-HSA-975871
Cell recruitment (pro-inflammatory response) R-HSA-9664424
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Disease R-HSA-1643685
Cytokine Signaling in Immune system R-HSA-1280215
Inflammasomes R-HSA-622312
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Innate Immune System R-HSA-168249
NIK-->noncanonical NF-kB signaling R-HSA-5676590
IkBA variant leads to EDA-ID R-HSA-5603029
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Interleukin-1 signaling R-HSA-9020702
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
C-type lectin receptors (CLRs) R-HSA-5621481
SUMOylation of immune response proteins R-HSA-4755510
Infectious disease R-HSA-5663205
Immune System R-HSA-168256
Chromatin organization R-HSA-4839726
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Interleukin-1 processing R-HSA-448706
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Leishmania infection R-HSA-9658195
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 family signaling R-HSA-446652
Metabolism of proteins R-HSA-392499
MyD88-independent TLR4 cascade R-HSA-166166
TRAF6 mediated NF-kB activation R-HSA-933542
Diseases of Immune System R-HSA-5260271
Chromatin modifying enzymes R-HSA-3247509
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Diseases associated with the TLR signaling cascade R-HSA-5602358
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Interleukin-1 processing R-HSA-448706
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Disease R-HSA-1643685
SUMOylation R-HSA-2990846
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Chromatin organization R-HSA-4839726
IkBA variant leads to EDA-ID R-HSA-5603029
Inflammasomes R-HSA-622312
Innate Immune System R-HSA-168249
CLEC7A (Dectin-1) signaling R-HSA-5607764
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Signaling by Interleukins R-HSA-449147
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Infectious disease R-HSA-5663205
Post-translational protein modification R-HSA-597592
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Leishmania infection R-HSA-9658195
PKMTs methylate histone lysines R-HSA-3214841
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MyD88 cascade initiated on plasma membrane R-HSA-975871
Metabolism of proteins R-HSA-392499
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
SUMOylation of immune response proteins R-HSA-4755510
Immune System R-HSA-168256
MyD88 dependent cascade initiated on endosome R-HSA-975155
Purinergic signaling in leishmaniasis infection R-HSA-9660826
NIK-->noncanonical NF-kB signaling R-HSA-5676590
The NLRP3 inflammasome R-HSA-844456
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Metabolism of proteins R-HSA-392499
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
IkBA variant leads to EDA-ID R-HSA-5603029
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 family signaling R-HSA-446652
Post-translational protein modification R-HSA-597592
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Toll-like Receptor Cascades R-HSA-168898
Infectious disease R-HSA-5663205
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Inflammasomes R-HSA-622312
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Diseases associated with the TLR signaling cascade R-HSA-5602358
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Purinergic signaling in leishmaniasis infection R-HSA-9660826
SUMOylation of immune response proteins R-HSA-4755510
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Leishmania infection R-HSA-9658195
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 cascade initiated on plasma membrane R-HSA-975871
Interleukin-1 signaling R-HSA-9020702
MyD88-independent TLR4 cascade R-HSA-166166
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Chromatin organization R-HSA-4839726
C-type lectin receptors (CLRs) R-HSA-5621481
Chromatin modifying enzymes R-HSA-3247509
TRAF6 mediated NF-kB activation R-HSA-933542
PKMTs methylate histone lysines R-HSA-3214841
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
The NLRP3 inflammasome R-HSA-844456
SUMOylation R-HSA-2990846
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MyD88 dependent cascade initiated on endosome R-HSA-975155
Diseases of Immune System R-HSA-5260271
Immune System R-HSA-168256
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Innate Immune System R-HSA-168249
Interleukin-1 processing R-HSA-448706
C-type lectin receptors (CLRs) R-HSA-5621481
Interleukin-1 family signaling R-HSA-446652
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
PKMTs methylate histone lysines R-HSA-3214841
TRAF6 mediated NF-kB activation R-HSA-933542
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Post-translational protein modification R-HSA-597592
Inflammasomes R-HSA-622312
Diseases of Immune System R-HSA-5260271
Chromatin modifying enzymes R-HSA-3247509
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll-like Receptor Cascades R-HSA-168898
Infectious disease R-HSA-5663205
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
SUMOylation of immune response proteins R-HSA-4755510
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Purinergic signaling in leishmaniasis infection R-HSA-9660826
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
MyD88 dependent cascade initiated on endosome R-HSA-975155
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Diseases associated with the TLR signaling cascade R-HSA-5602358
NIK-->noncanonical NF-kB signaling R-HSA-5676590
SUMOylation R-HSA-2990846
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Chromatin organization R-HSA-4839726
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Interleukins R-HSA-449147
Immune System R-HSA-168256
MyD88-independent TLR4 cascade R-HSA-166166
Cell recruitment (pro-inflammatory response) R-HSA-9664424
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Leishmania infection R-HSA-9658195
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
IkBA variant leads to EDA-ID R-HSA-5603029
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Disease R-HSA-1643685
Interleukin-1 processing R-HSA-448706
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
The NLRP3 inflammasome R-HSA-844456
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88-independent TLR4 cascade R-HSA-166166
Chromatin organization R-HSA-4839726
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Leishmania infection R-HSA-9658195
Innate Immune System R-HSA-168249
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Immune System R-HSA-168256
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-1 signaling R-HSA-9020702
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
Diseases of Immune System R-HSA-5260271
Toll-like Receptor Cascades R-HSA-168898
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases associated with the TLR signaling cascade R-HSA-5602358
The NLRP3 inflammasome R-HSA-844456
Disease R-HSA-1643685
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Chromatin modifying enzymes R-HSA-3247509
Interleukin-1 processing R-HSA-448706
Infectious disease R-HSA-5663205
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
SUMOylation R-HSA-2990846
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
PKMTs methylate histone lysines R-HSA-3214841
MyD88 dependent cascade initiated on endosome R-HSA-975155
Post-translational protein modification R-HSA-597592
SUMOylation of immune response proteins R-HSA-4755510
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Inflammasomes R-HSA-622312
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
Metabolism of proteins R-HSA-392499
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRAF6 mediated NF-kB activation R-HSA-933542
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Interleukin-1 family signaling R-HSA-446652
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Chromatin modifying enzymes R-HSA-3247509
The NLRP3 inflammasome R-HSA-844456
Immune System R-HSA-168256
Chromatin organization R-HSA-4839726
Cell recruitment (pro-inflammatory response) R-HSA-9664424
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Infectious disease R-HSA-5663205
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
MyD88-independent TLR4 cascade R-HSA-166166
MyD88 cascade initiated on plasma membrane R-HSA-975871
Interleukin-1 processing R-HSA-448706
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Leishmania infection R-HSA-9658195
CLEC7A (Dectin-1) signaling R-HSA-5607764
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476
PKMTs methylate histone lysines R-HSA-3214841
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Diseases associated with the TLR signaling cascade R-HSA-5602358
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Diseases of Immune System R-HSA-5260271
Toll-like Receptor Cascades R-HSA-168898
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NIK-->noncanonical NF-kB signaling R-HSA-5676590
TRAF6 mediated NF-kB activation R-HSA-933542
Post-translational protein modification R-HSA-597592
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
IkBA variant leads to EDA-ID R-HSA-5603029
Interleukin-1 signaling R-HSA-9020702
Purinergic signaling in leishmaniasis infection R-HSA-9660826
Innate Immune System R-HSA-168249
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
SUMOylation R-HSA-2990846
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963
SUMOylation of immune response proteins R-HSA-4755510
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Signaling by Interleukins R-HSA-449147
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Inflammasomes R-HSA-622312
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Metabolism of proteins R-HSA-392499
SUMO E3 ligases SUMOylate target proteins R-HSA-3108232
C-type lectin receptors (CLRs) R-HSA-5621481
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989

Expression Atlas ENSG00000077150
LRG display in Ensembl gene LRG_1347
NCBI gene (formerly Entrezgene) 4791
GeneCards 7795
HGNC Symbol HGNC:7795
MIM gene 164012
MIM morbid 615577
UniProtKB Gene Name Q00653
WikiGene 4791
Gene: EPAS1
Ensembl ID : ENSG00000116016
Description: endothelial PAS domain protein 1
Gene Synonyms: BHLHE73,HIF2A,HLF,MOP2,PASD2
1 APIs:
225 Possible Orthologues:

Pexophagy R-HSA-9664873
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular responses to stress R-HSA-2262752
Autophagy R-HSA-9612973
Post-translational protein modification R-HSA-597592
Macroautophagy R-HSA-1632852
Developmental Biology R-HSA-1266738
PTK6 Expression R-HSA-8849473
Cellular response to hypoxia R-HSA-1234174
Signaling by PTK6 R-HSA-8848021
Selective autophagy R-HSA-9663891
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Autophagy R-HSA-9612973
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Neddylation R-HSA-8951664
Macroautophagy R-HSA-1632852
Developmental Biology R-HSA-1266738
Pexophagy R-HSA-9664873
PTK6 Expression R-HSA-8849473
Cellular response to hypoxia R-HSA-1234174
Signaling by PTK6 R-HSA-8848021
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Selective autophagy R-HSA-9663891
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Post-translational protein modification R-HSA-597592
Metabolism of proteins R-HSA-392499
Selective autophagy R-HSA-9663891
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
PTK6 Expression R-HSA-8849473
Developmental Biology R-HSA-1266738
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
Signal Transduction R-HSA-162582
Signaling by PTK6 R-HSA-8848021
Pexophagy R-HSA-9664873
Neddylation R-HSA-8951664
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular responses to stress R-HSA-2262752
Macroautophagy R-HSA-1632852
Autophagy R-HSA-9612973
Cellular responses to stimuli R-HSA-8953897
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Macroautophagy R-HSA-1632852
Metabolism of proteins R-HSA-392499
Signal Transduction R-HSA-162582
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Pexophagy R-HSA-9664873
Cellular responses to stimuli R-HSA-8953897
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Autophagy R-HSA-9612973
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Selective autophagy R-HSA-9663891
Post-translational protein modification R-HSA-597592
Signaling by PTK6 R-HSA-8848021
Cellular response to hypoxia R-HSA-1234174
PTK6 Expression R-HSA-8849473
Neddylation R-HSA-8951664
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Pexophagy R-HSA-9664873
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Signaling by PTK6 R-HSA-8848021
Neddylation R-HSA-8951664
Cellular response to hypoxia R-HSA-1234174
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Macroautophagy R-HSA-1632852
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Signal Transduction R-HSA-162582
PTK6 Expression R-HSA-8849473
Autophagy R-HSA-9612973
Cellular responses to stimuli R-HSA-8953897
Selective autophagy R-HSA-9663891
Macroautophagy R-HSA-1632852
Neddylation R-HSA-8951664
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Signaling by PTK6 R-HSA-8848021
Cellular responses to stimuli R-HSA-8953897
Cellular responses to stress R-HSA-2262752
Selective autophagy R-HSA-9663891
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
PTK6 Expression R-HSA-8849473
Autophagy R-HSA-9612973
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Pexophagy R-HSA-9664873
Signal Transduction R-HSA-162582
PTK6 Expression R-HSA-8849473
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Post-translational protein modification R-HSA-597592
Selective autophagy R-HSA-9663891
Signaling by PTK6 R-HSA-8848021
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Cellular responses to stimuli R-HSA-8953897
Pexophagy R-HSA-9664873
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Cellular response to hypoxia R-HSA-1234174
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Autophagy R-HSA-9612973
Developmental Biology R-HSA-1266738
Cellular responses to stress R-HSA-2262752
Macroautophagy R-HSA-1632852
Neddylation R-HSA-8951664
PTK6 Expression R-HSA-8849473
Autophagy R-HSA-9612973
Cellular response to hypoxia R-HSA-1234174
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Pexophagy R-HSA-9664873
Cellular responses to stimuli R-HSA-8953897
Macroautophagy R-HSA-1632852
Signal Transduction R-HSA-162582
Metabolism of proteins R-HSA-392499
Signaling by PTK6 R-HSA-8848021
Selective autophagy R-HSA-9663891
Cellular responses to stress R-HSA-2262752
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Neddylation R-HSA-8951664
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Post-translational protein modification R-HSA-597592
Developmental Biology R-HSA-1266738
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Cellular responses to stress R-HSA-2262752
Macroautophagy R-HSA-1632852
Signaling by PTK6 R-HSA-8848021
Post-translational protein modification R-HSA-597592
Cellular responses to stimuli R-HSA-8953897
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Selective autophagy R-HSA-9663891
Metabolism of proteins R-HSA-392499
Cellular response to hypoxia R-HSA-1234174
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
PTK6 Expression R-HSA-8849473
Pexophagy R-HSA-9664873
Neddylation R-HSA-8951664
Signal Transduction R-HSA-162582
Developmental Biology R-HSA-1266738
Autophagy R-HSA-9612973
Autophagy R-HSA-9612973
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158
Macroautophagy R-HSA-1632852
Cellular responses to stimuli R-HSA-8953897
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Developmental Biology R-HSA-1266738
Signaling by PTK6 R-HSA-8848021
PTK6 Expression R-HSA-8849473
Post-translational protein modification R-HSA-597592
Selective autophagy R-HSA-9663891
Metabolism of proteins R-HSA-392499
Transcriptional regulation of pluripotent stem cells R-HSA-452723
Signal Transduction R-HSA-162582
Cellular response to hypoxia R-HSA-1234174
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927
Neddylation R-HSA-8951664
Pexophagy R-HSA-9664873
Cellular responses to stress R-HSA-2262752

Expression Atlas ENSG00000116016
NCBI gene (formerly Entrezgene) 2034
GeneCards 3374
HGNC Symbol HGNC:3374
MIM gene 603349
MIM morbid 611783
UniProtKB Gene Name Q99814
WikiGene 2034