Gene: AOC3
Ensembl ID : ENSG00000131471
Description: amine oxidase copper containing 3
Gene Synonyms: HPAO,VAP-1,VAP1
1 APIs:
317 Possible Orthologues:

Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Biological oxidations R-HSA-211859
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Phase I - Functionalization of compounds R-HSA-211945
Metabolism R-HSA-1430728
Biological oxidations R-HSA-211859

Expression Atlas ENSG00000131471
NCBI gene (formerly Entrezgene) 8639
GeneCards 550
HGNC Symbol HGNC:550
MIM gene 603735
UniProtKB Gene Name Q16853
WikiGene 8639
Gene: PIK3R1
Ensembl ID : ENSG00000145675
Description: phosphoinositide-3-kinase regulatory subunit 1
Gene Synonyms: GRB1,P85,P85-ALPHA,P85ALPHA
26 APIs:
259 Possible Orthologues:

Signaling by FGFR1 R-HSA-5654736
Disease R-HSA-1643685
Role of phospholipids in phagocytosis R-HSA-2029485
PI-3K cascade:FGFR3 R-HSA-5654710
RHO GTPase cycle R-HSA-9012999
Downstream signaling of activated FGFR2 R-HSA-5654696
Disease R-HSA-1643685
DAP12 interactions R-HSA-2172127
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by GPCR R-HSA-372790
Signaling by FGFR in disease R-HSA-1226099
RHOA GTPase cycle R-HSA-8980692
Cell-Cell communication R-HSA-1500931
Signaling by Nuclear Receptors R-HSA-9006931
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by EGFR R-HSA-177929
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RHOV GTPase cycle R-HSA-9013424
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by ERBB2 KD Mutants R-HSA-9664565
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by Erythropoietin R-HSA-9006335
Signaling by ERBB4 R-HSA-1236394
Signaling by EGFR in Cancer R-HSA-1643713
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by NTRK1 (TRKA) R-HSA-187037
Intracellular signaling by second messengers R-HSA-9006925
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RHOJ GTPase cycle R-HSA-9013409
Insulin receptor signalling cascade R-HSA-74751
Nervous system development R-HSA-9675108
PI-3K cascade:FGFR1 R-HSA-5654689
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
RND2 GTPase cycle R-HSA-9696270
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ESR-mediated signaling R-HSA-8939211
Nephrin family interactions R-HSA-373753
Signal Transduction R-HSA-162582
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Adaptive Immune System R-HSA-1280218
Phospholipid metabolism R-HSA-1483257
Signaling by VEGF R-HSA-194138
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PIP3 activates AKT signaling R-HSA-1257604
Metabolism R-HSA-1430728
Cytokine Signaling in Immune system R-HSA-1280215
RAF/MAP kinase cascade R-HSA-5673001
Signaling by SCF-KIT R-HSA-1433557
RHOU GTPase cycle R-HSA-9013420
Extra-nuclear estrogen signaling R-HSA-9009391
Hemostasis R-HSA-109582
Interleukin receptor SHC signaling R-HSA-912526
RHOF GTPase cycle R-HSA-9035034
CD28 co-stimulation R-HSA-389356
RAC1 GTPase cycle R-HSA-9013149
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Regulation of signaling by CBL R-HSA-912631
Signaling by NTRKs R-HSA-166520
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by KIT in disease R-HSA-9669938
Interleukin-7 signaling R-HSA-1266695
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by FGFR3 R-HSA-5654741
Platelet activation, signaling and aggregation R-HSA-76002
G alpha (q) signalling events R-HSA-416476
Downstream TCR signaling R-HSA-202424
RHOB GTPase cycle R-HSA-9013026
GPCR downstream signalling R-HSA-388396
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by EGFRvIII in Cancer R-HSA-5637812
PI Metabolism R-HSA-1483255
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Insulin receptor R-HSA-74752
Signaling by FGFR1 in disease R-HSA-5655302
GAB1 signalosome R-HSA-180292
Immune System R-HSA-168256
CD28 dependent PI3K/Akt signaling R-HSA-389357
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Metabolism of lipids R-HSA-556833
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by FLT3 fusion proteins R-HSA-9703465
Downstream signal transduction R-HSA-186763
Interleukin-2 family signaling R-HSA-451927
Signaling by ALK fusions and activated point mutants R-HSA-9725370
IGF1R signaling cascade R-HSA-2428924
PI3K/AKT Signaling in Cancer R-HSA-2219528
Costimulation by the CD28 family R-HSA-388841
Signaling by FGFR1 R-HSA-5654736
Activated NTRK3 signals through PI3K R-HSA-9603381
MAPK1/MAPK3 signaling R-HSA-5684996
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by FGFR4 R-HSA-5654743
RND3 GTPase cycle R-HSA-9696264
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Downstream signaling of activated FGFR3 R-HSA-5654708
RET signaling R-HSA-8853659
Tie2 Signaling R-HSA-210993
Signaling by ERBB2 R-HSA-1227986
RHOC GTPase cycle R-HSA-9013106
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
IRS-mediated signalling R-HSA-112399
RND1 GTPase cycle R-HSA-9696273
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RHOD GTPase cycle R-HSA-9013405
CDC42 GTPase cycle R-HSA-9013148
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by Interleukins R-HSA-449147
FLT3 signaling in disease R-HSA-9682385
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by NTRK3 (TRKC) R-HSA-9034015
Constitutive Signaling by EGFRvIII R-HSA-5637810
GPVI-mediated activation cascade R-HSA-114604
Signaling by FGFR2 R-HSA-5654738
Signaling by ALK R-HSA-201556
PI3K events in ERBB2 signaling R-HSA-1963642
Axon guidance R-HSA-422475
DAP12 signaling R-HSA-2424491
FLT3 Signaling R-HSA-9607240
Downstream signaling of activated FGFR1 R-HSA-5654687
PI-3K cascade:FGFR4 R-HSA-5654720
TCR signaling R-HSA-202403
Signaling by MET R-HSA-6806834
Signaling by PDGFR in disease R-HSA-9671555
MET activates PI3K/AKT signaling R-HSA-8851907
Negative regulation of the PI3K/AKT network R-HSA-199418
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RAC3 GTPase cycle R-HSA-9013423
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by PDGF R-HSA-186797
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GP1b-IX-V activation signalling R-HSA-430116
Signaling by ERBB2 ECD mutants R-HSA-9665348
RAC2 GTPase cycle R-HSA-9013404
Signaling by Rho GTPases R-HSA-194315
RHOG GTPase cycle R-HSA-9013408
MAPK family signaling cascades R-HSA-5683057
PI3K/AKT activation R-HSA-198203
Developmental Biology R-HSA-1266738
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by ALK in cancer R-HSA-9700206
Signaling by FGFR R-HSA-190236
Signaling by NTRK2 (TRKB) R-HSA-9006115
PI3K Cascade R-HSA-109704
Innate Immune System R-HSA-168249
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PI-3K cascade:FGFR2 R-HSA-5654695
RND3 GTPase cycle R-HSA-9696264
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Rho GTPases R-HSA-194315
Signaling by Erythropoietin R-HSA-9006335
RHOA GTPase cycle R-HSA-8980692
Signal Transduction R-HSA-162582
RAC2 GTPase cycle R-HSA-9013404
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
RHOC GTPase cycle R-HSA-9013106
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Metabolism R-HSA-1430728
Insulin receptor signalling cascade R-HSA-74751
Downstream signal transduction R-HSA-186763
Activated NTRK3 signals through PI3K R-HSA-9603381
RHOB GTPase cycle R-HSA-9013026
Signaling by FGFR1 in disease R-HSA-5655302
G alpha (q) signalling events R-HSA-416476
Signaling by FGFR in disease R-HSA-1226099
Regulation of signaling by CBL R-HSA-912631
Signaling by ALK in cancer R-HSA-9700206
Interleukin receptor SHC signaling R-HSA-912526
Signaling by NTRKs R-HSA-166520
Costimulation by the CD28 family R-HSA-388841
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by ERBB2 R-HSA-1227986
RHOD GTPase cycle R-HSA-9013405
Signaling by MET R-HSA-6806834
Developmental Biology R-HSA-1266738
Signaling by FLT3 fusion proteins R-HSA-9703465
Synthesis of PIPs at the plasma membrane R-HSA-1660499
RHOV GTPase cycle R-HSA-9013424
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by ERBB2 KD Mutants R-HSA-9664565
Downstream TCR signaling R-HSA-202424
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by EGFR R-HSA-177929
Signaling by FGFR4 R-HSA-5654743
Signaling by EGFRvIII in Cancer R-HSA-5637812
RAF/MAP kinase cascade R-HSA-5673001
ESR-mediated signaling R-HSA-8939211
Adaptive Immune System R-HSA-1280218
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by KIT in disease R-HSA-9669938
PI3K events in ERBB4 signaling R-HSA-1250342
MET activates PI3K/AKT signaling R-HSA-8851907
Signaling by VEGF R-HSA-194138
PI3K events in ERBB2 signaling R-HSA-1963642
DAP12 signaling R-HSA-2424491
CD28 co-stimulation R-HSA-389356
CDC42 GTPase cycle R-HSA-9013148
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by FGFR4 in disease R-HSA-5655291
RHOU GTPase cycle R-HSA-9013420
Signaling by FGFR3 R-HSA-5654741
PI-3K cascade:FGFR1 R-HSA-5654689
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by FGFR3 in disease R-HSA-5655332
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by PDGFR in disease R-HSA-9671555
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FLT3 Signaling R-HSA-9607240
PI3K/AKT activation R-HSA-198203
Signaling by ERBB4 R-HSA-1236394
RHOF GTPase cycle R-HSA-9035034
IRS-mediated signalling R-HSA-112399
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
MAPK family signaling cascades R-HSA-5683057
Interleukin-2 family signaling R-HSA-451927
MAPK1/MAPK3 signaling R-HSA-5684996
Cell-Cell communication R-HSA-1500931
Cytokine Signaling in Immune system R-HSA-1280215
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
VEGFA-VEGFR2 Pathway R-HSA-4420097
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHOG GTPase cycle R-HSA-9013408
PI3K Cascade R-HSA-109704
RAC3 GTPase cycle R-HSA-9013423
RHO GTPase cycle R-HSA-9012999
Tie2 Signaling R-HSA-210993
RAC1 GTPase cycle R-HSA-9013149
Interleukin-7 signaling R-HSA-1266695
CD28 dependent PI3K/Akt signaling R-HSA-389357
IRS-related events triggered by IGF1R R-HSA-2428928
Axon guidance R-HSA-422475
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by SCF-KIT R-HSA-1433557
RET signaling R-HSA-8853659
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
GP1b-IX-V activation signalling R-HSA-430116
Signaling by FGFR2 R-HSA-5654738
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by GPCR R-HSA-372790
RND1 GTPase cycle R-HSA-9696273
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by Insulin receptor R-HSA-74752
Negative regulation of the PI3K/AKT network R-HSA-199418
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR1 R-HSA-5654736
PI3K/AKT Signaling in Cancer R-HSA-2219528
GAB1 signalosome R-HSA-180292
Signaling by FGFR R-HSA-190236
GPVI-mediated activation cascade R-HSA-114604
Signaling by ERBB2 ECD mutants R-HSA-9665348
TCR signaling R-HSA-202403
Signaling by ALK R-HSA-201556
FLT3 signaling in disease R-HSA-9682385
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by NTRK3 (TRKC) R-HSA-9034015
Signaling by FGFR2 in disease R-HSA-5655253
PI Metabolism R-HSA-1483255
Disease R-HSA-1643685
Signaling by ERBB2 in Cancer R-HSA-1227990
GPCR downstream signalling R-HSA-388396
DAP12 interactions R-HSA-2172127
Signaling by Interleukins R-HSA-449147
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Cell surface interactions at the vascular wall R-HSA-202733
Hemostasis R-HSA-109582
IGF1R signaling cascade R-HSA-2428924
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by PDGF R-HSA-186797
RHOJ GTPase cycle R-HSA-9013409
Immune System R-HSA-168256
Nephrin family interactions R-HSA-373753
RND2 GTPase cycle R-HSA-9696270
Metabolism of lipids R-HSA-556833
Downstream signaling of activated FGFR1 R-HSA-5654687
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Nervous system development R-HSA-9675108
Innate Immune System R-HSA-168249
Activated NTRK2 signals through PI3K R-HSA-9028335
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by NTRK1 (TRKA) R-HSA-187037
Intracellular signaling by second messengers R-HSA-9006925
Phospholipid metabolism R-HSA-1483257
Extra-nuclear estrogen signaling R-HSA-9009391
Downstream signaling of activated FGFR4 R-HSA-5654716
PI3K Cascade R-HSA-109704
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RAC1 GTPase cycle R-HSA-9013149
CD28 dependent PI3K/Akt signaling R-HSA-389357
Downstream signal transduction R-HSA-186763
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by FGFR in disease R-HSA-1226099
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
CD28 co-stimulation R-HSA-389356
PI Metabolism R-HSA-1483255
Cytokine Signaling in Immune system R-HSA-1280215
RHOD GTPase cycle R-HSA-9013405
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by Rho GTPases R-HSA-194315
PI3K/AKT Signaling in Cancer R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
RHOV GTPase cycle R-HSA-9013424
Constitutive Signaling by EGFRvIII R-HSA-5637810
Metabolism of lipids R-HSA-556833
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signal Transduction R-HSA-162582
RHOG GTPase cycle R-HSA-9013408
Costimulation by the CD28 family R-HSA-388841
Signaling by SCF-KIT R-HSA-1433557
RND3 GTPase cycle R-HSA-9696264
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by FLT3 fusion proteins R-HSA-9703465
RHOU GTPase cycle R-HSA-9013420
Regulation of signaling by CBL R-HSA-912631
Innate Immune System R-HSA-168249
Platelet activation, signaling and aggregation R-HSA-76002
MAPK family signaling cascades R-HSA-5683057
Nephrin family interactions R-HSA-373753
Signaling by ERBB2 in Cancer R-HSA-1227990
PI-3K cascade:FGFR4 R-HSA-5654720
RAF/MAP kinase cascade R-HSA-5673001
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
IRS-mediated signalling R-HSA-112399
PI-3K cascade:FGFR1 R-HSA-5654689
Developmental Biology R-HSA-1266738
Signaling by NTRK1 (TRKA) R-HSA-187037
IGF1R signaling cascade R-HSA-2428924
Signaling by EGFRvIII in Cancer R-HSA-5637812
Immune System R-HSA-168256
G alpha (q) signalling events R-HSA-416476
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by ALK R-HSA-201556
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by NTRKs R-HSA-166520
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by NTRK3 (TRKC) R-HSA-9034015
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by FGFR3 R-HSA-5654741
RAC2 GTPase cycle R-HSA-9013404
Signaling by GPCR R-HSA-372790
FLT3 Signaling R-HSA-9607240
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RET signaling R-HSA-8853659
RHOA GTPase cycle R-HSA-8980692
RHO GTPase cycle R-HSA-9012999
Intracellular signaling by second messengers R-HSA-9006925
Signaling by ERBB2 R-HSA-1227986
PI-3K cascade:FGFR3 R-HSA-5654710
Interleukin receptor SHC signaling R-HSA-912526
Signaling by ERBB4 R-HSA-1236394
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by FGFR2 R-HSA-5654738
Disease R-HSA-1643685
RHOF GTPase cycle R-HSA-9035034
TCR signaling R-HSA-202403
Signaling by Insulin receptor R-HSA-74752
Metabolism R-HSA-1430728
Signaling by FGFR R-HSA-190236
Signaling by KIT in disease R-HSA-9669938
Signaling by EGFR R-HSA-177929
Adaptive Immune System R-HSA-1280218
PI3K events in ERBB4 signaling R-HSA-1250342
Phospholipid metabolism R-HSA-1483257
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
FLT3 signaling in disease R-HSA-9682385
Signaling by FGFR4 R-HSA-5654743
PI3K/AKT activation R-HSA-198203
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
RND1 GTPase cycle R-HSA-9696273
CDC42 GTPase cycle R-HSA-9013148
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
PI-3K cascade:FGFR2 R-HSA-5654695
Role of phospholipids in phagocytosis R-HSA-2029485
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Activated NTRK2 signals through PI3K R-HSA-9028335
Hemostasis R-HSA-109582
Insulin receptor signalling cascade R-HSA-74751
Signaling by Interleukins R-HSA-449147
Downstream signaling of activated FGFR3 R-HSA-5654708
ESR-mediated signaling R-HSA-8939211
Signaling by PDGFR in disease R-HSA-9671555
GPVI-mediated activation cascade R-HSA-114604
GPCR downstream signalling R-HSA-388396
RAC3 GTPase cycle R-HSA-9013423
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Activated NTRK3 signals through PI3K R-HSA-9603381
RHOB GTPase cycle R-HSA-9013026
DAP12 interactions R-HSA-2172127
Interleukin-7 signaling R-HSA-1266695
RND2 GTPase cycle R-HSA-9696270
RHOC GTPase cycle R-HSA-9013106
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by MET R-HSA-6806834
Signaling by VEGF R-HSA-194138
VEGFA-VEGFR2 Pathway R-HSA-4420097
DAP12 signaling R-HSA-2424491
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-2 family signaling R-HSA-451927
Axon guidance R-HSA-422475
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by the B Cell Receptor (BCR) R-HSA-983705
RHOJ GTPase cycle R-HSA-9013409
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by PDGF R-HSA-186797
Nervous system development R-HSA-9675108
Cell-Cell communication R-HSA-1500931
GP1b-IX-V activation signalling R-HSA-430116
Downstream TCR signaling R-HSA-202424
Signaling by ERBB2 ECD mutants R-HSA-9665348
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Tie2 Signaling R-HSA-210993
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by Erythropoietin R-HSA-9006335
Signaling by Nuclear Receptors R-HSA-9006931
PIP3 activates AKT signaling R-HSA-1257604
Extra-nuclear estrogen signaling R-HSA-9009391
GAB1 signalosome R-HSA-180292
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ALK in cancer R-HSA-9700206
MET activates PI3K/AKT signaling R-HSA-8851907
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Intracellular signaling by second messengers R-HSA-9006925
Downstream signaling of activated FGFR2 R-HSA-5654696
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by ERBB2 R-HSA-1227986
Signaling by FGFR1 R-HSA-5654736
Signaling by FLT3 fusion proteins R-HSA-9703465
Extra-nuclear estrogen signaling R-HSA-9009391
PI-3K cascade:FGFR1 R-HSA-5654689
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR4 R-HSA-5654720
Costimulation by the CD28 family R-HSA-388841
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
ESR-mediated signaling R-HSA-8939211
RHOG GTPase cycle R-HSA-9013408
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ALK in cancer R-HSA-9700206
MAPK1/MAPK3 signaling R-HSA-5684996
RHOU GTPase cycle R-HSA-9013420
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
RET signaling R-HSA-8853659
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Downstream signaling of activated FGFR1 R-HSA-5654687
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
IRS-related events triggered by IGF1R R-HSA-2428928
GPVI-mediated activation cascade R-HSA-114604
Signaling by Nuclear Receptors R-HSA-9006931
Immune System R-HSA-168256
GPCR downstream signalling R-HSA-388396
PI3K Cascade R-HSA-109704
Insulin receptor signalling cascade R-HSA-74751
Signaling by EGFRvIII in Cancer R-HSA-5637812
FGFR1 mutant receptor activation R-HSA-1839124
Cell surface interactions at the vascular wall R-HSA-202733
RHOJ GTPase cycle R-HSA-9013409
Axon guidance R-HSA-422475
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by FGFR2 R-HSA-5654738
G alpha (q) signalling events R-HSA-416476
RHOD GTPase cycle R-HSA-9013405
Signaling by NTRK3 (TRKC) R-HSA-9034015
PI Metabolism R-HSA-1483255
Signaling by FGFR3 R-HSA-5654741
PIP3 activates AKT signaling R-HSA-1257604
Signal Transduction R-HSA-162582
Signaling by PDGF R-HSA-186797
Signaling by Insulin receptor R-HSA-74752
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Developmental Biology R-HSA-1266738
Constitutive Signaling by EGFRvIII R-HSA-5637810
RAC2 GTPase cycle R-HSA-9013404
Downstream signaling of activated FGFR3 R-HSA-5654708
PI3K events in ERBB4 signaling R-HSA-1250342
RAC3 GTPase cycle R-HSA-9013423
PI-3K cascade:FGFR3 R-HSA-5654710
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Nephrin family interactions R-HSA-373753
PI3K/AKT activation R-HSA-198203
Signaling by EGFR R-HSA-177929
FLT3 Signaling R-HSA-9607240
Regulation of signaling by CBL R-HSA-912631
Negative regulation of the PI3K/AKT network R-HSA-199418
Downstream TCR signaling R-HSA-202424
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by NTRKs R-HSA-166520
FLT3 signaling in disease R-HSA-9682385
Innate Immune System R-HSA-168249
Cytokine Signaling in Immune system R-HSA-1280215
IRS-mediated signalling R-HSA-112399
Hemostasis R-HSA-109582
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Tie2 Signaling R-HSA-210993
GAB1 signalosome R-HSA-180292
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by GPCR R-HSA-372790
Signaling by FGFR R-HSA-190236
Nervous system development R-HSA-9675108
Signaling by FGFR in disease R-HSA-1226099
Phospholipid metabolism R-HSA-1483257
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by KIT in disease R-HSA-9669938
Metabolism of lipids R-HSA-556833
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by Interleukins R-HSA-449147
Signaling by NTRK2 (TRKB) R-HSA-9006115
Interleukin-2 family signaling R-HSA-451927
RHOC GTPase cycle R-HSA-9013106
Adaptive Immune System R-HSA-1280218
CDC42 GTPase cycle R-HSA-9013148
DAP12 interactions R-HSA-2172127
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
GP1b-IX-V activation signalling R-HSA-430116
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by PDGFR in disease R-HSA-9671555
MET activates PI3K/AKT signaling R-HSA-8851907
CD28 dependent PI3K/Akt signaling R-HSA-389357
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RHOV GTPase cycle R-HSA-9013424
RAC1 GTPase cycle R-HSA-9013149
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
RND3 GTPase cycle R-HSA-9696264
Signaling by NTRK1 (TRKA) R-HSA-187037
RND1 GTPase cycle R-HSA-9696273
RHO GTPase cycle R-HSA-9012999
Downstream signal transduction R-HSA-186763
Signaling by ERBB2 KD Mutants R-HSA-9664565
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by FGFR4 R-HSA-5654743
TCR signaling R-HSA-202403
Signaling by SCF-KIT R-HSA-1433557
Signaling by Erythropoietin R-HSA-9006335
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Synthesis of PIPs at the plasma membrane R-HSA-1660499
MAPK family signaling cascades R-HSA-5683057
Interleukin receptor SHC signaling R-HSA-912526
RHOB GTPase cycle R-HSA-9013026
RND2 GTPase cycle R-HSA-9696270
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Cell-Cell communication R-HSA-1500931
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Interleukin-7 signaling R-HSA-1266695
Signaling by MET R-HSA-6806834
RAF/MAP kinase cascade R-HSA-5673001
RHOA GTPase cycle R-HSA-8980692
DAP12 signaling R-HSA-2424491
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by FGFR4 in disease R-HSA-5655291
PI3K/AKT Signaling in Cancer R-HSA-2219528
Disease R-HSA-1643685
Signaling by FGFR3 in disease R-HSA-5655332
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases R-HSA-194315
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by VEGF R-HSA-194138
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by ERBB4 R-HSA-1236394
CD28 co-stimulation R-HSA-389356
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by ALK R-HSA-201556
Metabolism R-HSA-1430728
RHOF GTPase cycle R-HSA-9035034
Signaling by PDGF R-HSA-186797
Signaling by ERBB2 R-HSA-1227986
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by PDGFR in disease R-HSA-9671555
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by NTRKs R-HSA-166520
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Disease R-HSA-1643685
Platelet activation, signaling and aggregation R-HSA-76002
Hemostasis R-HSA-109582
IRS-related events triggered by IGF1R R-HSA-2428928
RHOJ GTPase cycle R-HSA-9013409
PIP3 activates AKT signaling R-HSA-1257604
Signaling by FGFR1 in disease R-HSA-5655302
GAB1 signalosome R-HSA-180292
Role of phospholipids in phagocytosis R-HSA-2029485
Downstream signaling of activated FGFR1 R-HSA-5654687
RHOU GTPase cycle R-HSA-9013420
GP1b-IX-V activation signalling R-HSA-430116
Signaling by EGFR R-HSA-177929
Tie2 Signaling R-HSA-210993
PI3K events in ERBB2 signaling R-HSA-1963642
DAP12 interactions R-HSA-2172127
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
GPCR downstream signalling R-HSA-388396
RAC2 GTPase cycle R-HSA-9013404
IGF1R signaling cascade R-HSA-2428924
RND2 GTPase cycle R-HSA-9696270
PI-3K cascade:FGFR4 R-HSA-5654720
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RHOC GTPase cycle R-HSA-9013106
Nervous system development R-HSA-9675108
PI3K Cascade R-HSA-109704
Signaling by VEGF R-HSA-194138
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Activated NTRK3 signals through PI3K R-HSA-9603381
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Downstream signaling of activated FGFR3 R-HSA-5654708
Interleukin receptor SHC signaling R-HSA-912526
Axon guidance R-HSA-422475
Signaling by FGFR R-HSA-190236
PI Metabolism R-HSA-1483255
RHOD GTPase cycle R-HSA-9013405
Signaling by the B Cell Receptor (BCR) R-HSA-983705
MAPK family signaling cascades R-HSA-5683057
RAC1 GTPase cycle R-HSA-9013149
Signaling by FGFR4 R-HSA-5654743
Downstream signal transduction R-HSA-186763
Signaling by NTRK1 (TRKA) R-HSA-187037
IRS-mediated signalling R-HSA-112399
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
Signaling by Erythropoietin R-HSA-9006335
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by GPCR R-HSA-372790
Signaling by FGFR2 R-HSA-5654738
TCR signaling R-HSA-202403
Intracellular signaling by second messengers R-HSA-9006925
Insulin receptor signalling cascade R-HSA-74751
Signaling by FLT3 fusion proteins R-HSA-9703465
CDC42 GTPase cycle R-HSA-9013148
Immune System R-HSA-168256
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by FGFR3 R-HSA-5654741
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by KIT in disease R-HSA-9669938
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Nephrin family interactions R-HSA-373753
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
RHOG GTPase cycle R-HSA-9013408
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by ERBB2 ECD mutants R-HSA-9665348
Developmental Biology R-HSA-1266738
FLT3 signaling in disease R-HSA-9682385
Signaling by ALK R-HSA-201556
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-7 signaling R-HSA-1266695
RHOA GTPase cycle R-HSA-8980692
Downstream TCR signaling R-HSA-202424
Innate Immune System R-HSA-168249
GPVI-mediated activation cascade R-HSA-114604
Costimulation by the CD28 family R-HSA-388841
RAC3 GTPase cycle R-HSA-9013423
DAP12 signaling R-HSA-2424491
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Rho GTPases R-HSA-194315
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by FGFR1 R-HSA-5654736
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by ERBB4 R-HSA-1236394
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downstream signaling of activated FGFR2 R-HSA-5654696
ESR-mediated signaling R-HSA-8939211
Metabolism of lipids R-HSA-556833
Signaling by FGFR2 in disease R-HSA-5655253
Regulation of signaling by CBL R-HSA-912631
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Extra-nuclear estrogen signaling R-HSA-9009391
Cytokine Signaling in Immune system R-HSA-1280215
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by Insulin receptor R-HSA-74752
Cell-Cell communication R-HSA-1500931
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Interleukin-2 family signaling R-HSA-451927
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by MET R-HSA-6806834
Constitutive Signaling by EGFRvIII R-HSA-5637810
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Activated NTRK2 signals through PI3K R-HSA-9028335
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by FGFR in disease R-HSA-1226099
Signaling by NTRK3 (TRKC) R-HSA-9034015
PI3K/AKT activation R-HSA-198203
Adaptive Immune System R-HSA-1280218
RND3 GTPase cycle R-HSA-9696264
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by ERBB2 KD Mutants R-HSA-9664565
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by ALK in cancer R-HSA-9700206
RET signaling R-HSA-8853659
Phospholipid metabolism R-HSA-1483257
RHO GTPase cycle R-HSA-9012999
Signaling by Interleukins R-HSA-449147
G alpha (q) signalling events R-HSA-416476
Signal Transduction R-HSA-162582
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by FGFR3 in disease R-HSA-5655332
FLT3 Signaling R-HSA-9607240
CD28 co-stimulation R-HSA-389356
RHOV GTPase cycle R-HSA-9013424
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
VEGFA-VEGFR2 Pathway R-HSA-4420097
Metabolism R-HSA-1430728
RAF/MAP kinase cascade R-HSA-5673001
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by NTRK2 (TRKB) R-HSA-9006115
RHOB GTPase cycle R-HSA-9013026
RHOF GTPase cycle R-HSA-9035034
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
RND1 GTPase cycle R-HSA-9696273
MET activates PI3K/AKT signaling R-HSA-8851907
Hemostasis R-HSA-109582
Signaling by Erythropoietin R-HSA-9006335
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by MET R-HSA-6806834
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by FLT3 fusion proteins R-HSA-9703465
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 KD Mutants R-HSA-9664565
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI-3K cascade:FGFR2 R-HSA-5654695
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
RHO GTPase cycle R-HSA-9012999
MET activates PI3K/AKT signaling R-HSA-8851907
Insulin receptor signalling cascade R-HSA-74751
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
CD28 co-stimulation R-HSA-389356
Signaling by FGFR3 in disease R-HSA-5655332
Immune System R-HSA-168256
Signaling by NTRKs R-HSA-166520
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin receptor SHC signaling R-HSA-912526
PI3K/AKT activation R-HSA-198203
Metabolism R-HSA-1430728
Signaling by ERBB2 R-HSA-1227986
DAP12 signaling R-HSA-2424491
RHOB GTPase cycle R-HSA-9013026
RHOG GTPase cycle R-HSA-9013408
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PIP3 activates AKT signaling R-HSA-1257604
DAP12 interactions R-HSA-2172127
Signaling by Rho GTPases R-HSA-194315
RAC1 GTPase cycle R-HSA-9013149
RHOV GTPase cycle R-HSA-9013424
Nephrin family interactions R-HSA-373753
IRS-related events triggered by IGF1R R-HSA-2428928
Innate Immune System R-HSA-168249
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
RHOF GTPase cycle R-HSA-9035034
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by Insulin receptor R-HSA-74752
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Costimulation by the CD28 family R-HSA-388841
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
PI3K/AKT Signaling in Cancer R-HSA-2219528
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by PDGFR in disease R-HSA-9671555
PI3K events in ERBB2 signaling R-HSA-1963642
Cytokine Signaling in Immune system R-HSA-1280215
Cell surface interactions at the vascular wall R-HSA-202733
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by KIT in disease R-HSA-9669938
Signaling by FGFR4 R-HSA-5654743
Signaling by Interleukins R-HSA-449147
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by NTRK3 (TRKC) R-HSA-9034015
Developmental Biology R-HSA-1266738
Adaptive Immune System R-HSA-1280218
PI Metabolism R-HSA-1483255
TCR signaling R-HSA-202403
Signaling by GPCR R-HSA-372790
RHOA GTPase cycle R-HSA-8980692
Downstream signal transduction R-HSA-186763
Constitutive Signaling by EGFRvIII R-HSA-5637810
Signaling by FGFR3 R-HSA-5654741
RHOD GTPase cycle R-HSA-9013405
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
MAPK family signaling cascades R-HSA-5683057
RAC2 GTPase cycle R-HSA-9013404
Phospholipid metabolism R-HSA-1483257
RND2 GTPase cycle R-HSA-9696270
CDC42 GTPase cycle R-HSA-9013148
Signaling by SCF-KIT R-HSA-1433557
ESR-mediated signaling R-HSA-8939211
Signaling by NTRK1 (TRKA) R-HSA-187037
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Axon guidance R-HSA-422475
Signaling by EGFR in Cancer R-HSA-1643713
PI3K Cascade R-HSA-109704
Signaling by FGFR R-HSA-190236
Extra-nuclear estrogen signaling R-HSA-9009391
Disease R-HSA-1643685
Interleukin-7 signaling R-HSA-1266695
Negative regulation of the PI3K/AKT network R-HSA-199418
Metabolism of lipids R-HSA-556833
Interleukin-2 family signaling R-HSA-451927
IGF1R signaling cascade R-HSA-2428924
Signal Transduction R-HSA-162582
Regulation of signaling by CBL R-HSA-912631
Platelet activation, signaling and aggregation R-HSA-76002
Intracellular signaling by second messengers R-HSA-9006925
Nervous system development R-HSA-9675108
RHOC GTPase cycle R-HSA-9013106
Signaling by ALK in cancer R-HSA-9700206
Downstream signaling of activated FGFR2 R-HSA-5654696
PI-3K cascade:FGFR4 R-HSA-5654720
Signaling by EGFRvIII in Cancer R-HSA-5637812
Cell-Cell communication R-HSA-1500931
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
FLT3 signaling in disease R-HSA-9682385
VEGFA-VEGFR2 Pathway R-HSA-4420097
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
G alpha (q) signalling events R-HSA-416476
Signaling by PDGF R-HSA-186797
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by FGFR2 in disease R-HSA-5655253
RND3 GTPase cycle R-HSA-9696264
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
CD28 dependent PI3K/Akt signaling R-HSA-389357
FLT3 Signaling R-HSA-9607240
Signaling by ALK R-HSA-201556
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by FGFR2 R-HSA-5654738
RET signaling R-HSA-8853659
RHOU GTPase cycle R-HSA-9013420
Downstream TCR signaling R-HSA-202424
PI-3K cascade:FGFR1 R-HSA-5654689
RHOJ GTPase cycle R-HSA-9013409
Role of phospholipids in phagocytosis R-HSA-2029485
GPCR downstream signalling R-HSA-388396
Signaling by Nuclear Receptors R-HSA-9006931
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by EGFR R-HSA-177929
IRS-mediated signalling R-HSA-112399
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
RAC3 GTPase cycle R-HSA-9013423
Signaling by FGFR1 R-HSA-5654736
Signaling by FGFR in disease R-HSA-1226099
Signaling by ERBB4 R-HSA-1236394
PI3K events in ERBB4 signaling R-HSA-1250342
RND1 GTPase cycle R-HSA-9696273
Activated NTRK2 signals through PI3K R-HSA-9028335
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Downstream signaling of activated FGFR1 R-HSA-5654687
GAB1 signalosome R-HSA-180292
Signaling by VEGF R-HSA-194138
Tie2 Signaling R-HSA-210993
GP1b-IX-V activation signalling R-HSA-430116
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by ERBB2 ECD mutants R-HSA-9665348
IRS-mediated signalling R-HSA-112399
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Interleukins R-HSA-449147
Axon guidance R-HSA-422475
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Platelet activation, signaling and aggregation R-HSA-76002
PI3K events in ERBB4 signaling R-HSA-1250342
Signaling by FGFR in disease R-HSA-1226099
Signaling by VEGF R-HSA-194138
FGFR1 mutant receptor activation R-HSA-1839124
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by SCF-KIT R-HSA-1433557
Downstream TCR signaling R-HSA-202424
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by FGFR4 R-HSA-5654743
RHOJ GTPase cycle R-HSA-9013409
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by FGFR4 in disease R-HSA-5655291
CD28 dependent PI3K/Akt signaling R-HSA-389357
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by EGFR in Cancer R-HSA-1643713
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by NTRK3 (TRKC) R-HSA-9034015
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI-3K cascade:FGFR2 R-HSA-5654695
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
TCR signaling R-HSA-202403
Downstream signaling of activated FGFR4 R-HSA-5654716
PI-3K cascade:FGFR3 R-HSA-5654710
Activated NTRK3 signals through PI3K R-HSA-9603381
RHOG GTPase cycle R-HSA-9013408
Metabolism of lipids R-HSA-556833
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Metabolism R-HSA-1430728
Signaling by KIT in disease R-HSA-9669938
Signaling by FLT3 fusion proteins R-HSA-9703465
RHOB GTPase cycle R-HSA-9013026
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by FGFR1 R-HSA-5654736
Signaling by PDGFR in disease R-HSA-9671555
DAP12 interactions R-HSA-2172127
Nephrin family interactions R-HSA-373753
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by GPCR R-HSA-372790
Signaling by EGFRvIII in Cancer R-HSA-5637812
RHOF GTPase cycle R-HSA-9035034
Signaling by FGFR3 R-HSA-5654741
Regulation of signaling by CBL R-HSA-912631
Signaling by FGFR1 in disease R-HSA-5655302
PI-3K cascade:FGFR4 R-HSA-5654720
Intracellular signaling by second messengers R-HSA-9006925
Role of phospholipids in phagocytosis R-HSA-2029485
Signaling by ERBB2 KD Mutants R-HSA-9664565
RND3 GTPase cycle R-HSA-9696264
Developmental Biology R-HSA-1266738
GP1b-IX-V activation signalling R-HSA-430116
RHOV GTPase cycle R-HSA-9013424
Downstream signaling of activated FGFR1 R-HSA-5654687
MET activates PI3K/AKT signaling R-HSA-8851907
RHOU GTPase cycle R-HSA-9013420
G alpha (q) signalling events R-HSA-416476
GPVI-mediated activation cascade R-HSA-114604
Constitutive Signaling by EGFRvIII R-HSA-5637810
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RAC3 GTPase cycle R-HSA-9013423
Interleukin-7 signaling R-HSA-1266695
RHOA GTPase cycle R-HSA-8980692
GPCR downstream signalling R-HSA-388396
Signaling by FGFR2 in disease R-HSA-5655253
PI3K Cascade R-HSA-109704
PI3K/AKT activation R-HSA-198203
Insulin receptor signalling cascade R-HSA-74751
Nervous system development R-HSA-9675108
Signaling by Erythropoietin R-HSA-9006335
Signaling by Insulin receptor R-HSA-74752
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
FLT3 Signaling R-HSA-9607240
Signaling by ERBB2 R-HSA-1227986
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Signaling by Nuclear Receptors R-HSA-9006931
DAP12 signaling R-HSA-2424491
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
GAB1 signalosome R-HSA-180292
IGF1R signaling cascade R-HSA-2428924
CD28 co-stimulation R-HSA-389356
Phospholipid metabolism R-HSA-1483257
Signaling by FGFR R-HSA-190236
Adaptive Immune System R-HSA-1280218
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Rho GTPases R-HSA-194315
Signaling by EGFR R-HSA-177929
Cell surface interactions at the vascular wall R-HSA-202733
Extra-nuclear estrogen signaling R-HSA-9009391
RAC1 GTPase cycle R-HSA-9013149
CDC42 GTPase cycle R-HSA-9013148
Signaling by ERBB4 R-HSA-1236394
Signaling by ALK fusions and activated point mutants R-HSA-9725370
RND1 GTPase cycle R-HSA-9696273
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Activated NTRK2 signals through PI3K R-HSA-9028335
RND2 GTPase cycle R-HSA-9696270
PIP3 activates AKT signaling R-HSA-1257604
Signaling by NTRKs R-HSA-166520
VEGFA-VEGFR2 Pathway R-HSA-4420097
Immune System R-HSA-168256
Signaling by MET R-HSA-6806834
RHOD GTPase cycle R-HSA-9013405
Costimulation by the CD28 family R-HSA-388841
PI3K events in ERBB2 signaling R-HSA-1963642
RHOC GTPase cycle R-HSA-9013106
RET signaling R-HSA-8853659
Innate Immune System R-HSA-168249
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Downstream signal transduction R-HSA-186763
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Signaling by PDGF R-HSA-186797
MAPK family signaling cascades R-HSA-5683057
RAC2 GTPase cycle R-HSA-9013404
Signaling by ALK R-HSA-201556
Tie2 Signaling R-HSA-210993
Downstream signaling of activated FGFR3 R-HSA-5654708
FLT3 signaling in disease R-HSA-9682385
Signaling by ALK in cancer R-HSA-9700206
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by FGFR2 R-HSA-5654738
Interleukin receptor SHC signaling R-HSA-912526
Signal Transduction R-HSA-162582
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
RHO GTPase cycle R-HSA-9012999
Signaling by NTRK2 (TRKB) R-HSA-9006115
Hemostasis R-HSA-109582
PI Metabolism R-HSA-1483255
PI-3K cascade:FGFR1 R-HSA-5654689
ESR-mediated signaling R-HSA-8939211
Signaling by ERBB2 in Cancer R-HSA-1227990
Cell-Cell communication R-HSA-1500931
Disease R-HSA-1643685
Interleukin-2 family signaling R-HSA-451927
Signaling by FGFR3 in disease R-HSA-5655332
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Downstream signal transduction R-HSA-186763
MAPK family signaling cascades R-HSA-5683057
Innate Immune System R-HSA-168249
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
RAF/MAP kinase cascade R-HSA-5673001
Downstream signaling of activated FGFR4 R-HSA-5654716
Signaling by ERBB2 KD Mutants R-HSA-9664565
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Signaling by Rho GTPases R-HSA-194315
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by PDGF R-HSA-186797
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by VEGF R-HSA-194138
MET activates PI3K/AKT signaling R-HSA-8851907
CDC42 GTPase cycle R-HSA-9013148
PI-3K cascade:FGFR2 R-HSA-5654695
RHOJ GTPase cycle R-HSA-9013409
RHOG GTPase cycle R-HSA-9013408
Signaling by Erythropoietin R-HSA-9006335
Signaling by GPCR R-HSA-372790
Signaling by ERBB2 R-HSA-1227986
RAC2 GTPase cycle R-HSA-9013404
Signaling by ERBB2 ECD mutants R-HSA-9665348
Phospholipid metabolism R-HSA-1483257
RHOV GTPase cycle R-HSA-9013424
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Costimulation by the CD28 family R-HSA-388841
Signaling by ERBB2 in Cancer R-HSA-1227990
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signal Transduction R-HSA-162582
Insulin receptor signalling cascade R-HSA-74751
PI Metabolism R-HSA-1483255
Signaling by PDGFR in disease R-HSA-9671555
PI-3K cascade:FGFR4 R-HSA-5654720
Hemostasis R-HSA-109582
Negative regulation of the PI3K/AKT network R-HSA-199418
Signaling by NTRK3 (TRKC) R-HSA-9034015
Platelet activation, signaling and aggregation R-HSA-76002
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by FGFR2 in disease R-HSA-5655253
RHOB GTPase cycle R-HSA-9013026
TCR signaling R-HSA-202403
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by NTRK2 (TRKB) R-HSA-9006115
IGF1R signaling cascade R-HSA-2428924
PI-3K cascade:FGFR3 R-HSA-5654710
Signaling by ALK R-HSA-201556
Signaling by FGFR R-HSA-190236
Signaling by FGFR1 R-HSA-5654736
Interleukin-7 signaling R-HSA-1266695
RAC3 GTPase cycle R-HSA-9013423
Regulation of signaling by CBL R-HSA-912631
Signaling by Nuclear Receptors R-HSA-9006931
Extra-nuclear estrogen signaling R-HSA-9009391
RHOF GTPase cycle R-HSA-9035034
IRS-related events triggered by IGF1R R-HSA-2428928
G alpha (q) signalling events R-HSA-416476
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
Signaling by KIT in disease R-HSA-9669938
ESR-mediated signaling R-HSA-8939211
GPVI-mediated activation cascade R-HSA-114604
Interleukin-2 family signaling R-HSA-451927
PI3K events in ERBB2 signaling R-HSA-1963642
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
Signaling by ALK in cancer R-HSA-9700206
RHOC GTPase cycle R-HSA-9013106
DAP12 interactions R-HSA-2172127
Signaling by FGFR3 R-HSA-5654741
Signaling by EGFR R-HSA-177929
VEGFA-VEGFR2 Pathway R-HSA-4420097
FLT3 Signaling R-HSA-9607240
RAC1 GTPase cycle R-HSA-9013149
Tie2 Signaling R-HSA-210993
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Signaling by FLT3 fusion proteins R-HSA-9703465
PIP3 activates AKT signaling R-HSA-1257604
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by EGFR in Cancer R-HSA-1643713
PI3K Cascade R-HSA-109704
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by the B Cell Receptor (BCR) R-HSA-983705
FGFR1 mutant receptor activation R-HSA-1839124
Immune System R-HSA-168256
Metabolism R-HSA-1430728
IRS-mediated signalling R-HSA-112399
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
RND1 GTPase cycle R-HSA-9696273
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Interleukin receptor SHC signaling R-HSA-912526
Signaling by NTRKs R-HSA-166520
Nephrin family interactions R-HSA-373753
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Role of phospholipids in phagocytosis R-HSA-2029485
CD28 co-stimulation R-HSA-389356
MAPK1/MAPK3 signaling R-HSA-5684996
RND3 GTPase cycle R-HSA-9696264
Signaling by FGFR in disease R-HSA-1226099
Signaling by SCF-KIT R-HSA-1433557
PI3K events in ERBB4 signaling R-HSA-1250342
RHOD GTPase cycle R-HSA-9013405
GP1b-IX-V activation signalling R-HSA-430116
RHO GTPase cycle R-HSA-9012999
PI-3K cascade:FGFR1 R-HSA-5654689
Activated NTRK3 signals through PI3K R-HSA-9603381
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Cell surface interactions at the vascular wall R-HSA-202733
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by Interleukins R-HSA-449147
Cytokine Signaling in Immune system R-HSA-1280215
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
PI3K/AKT activation R-HSA-198203
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by MET R-HSA-6806834
Constitutive Signaling by EGFRvIII R-HSA-5637810
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Axon guidance R-HSA-422475
Signaling by FGFR4 in disease R-HSA-5655291
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by FGFR4 R-HSA-5654743
RHOA GTPase cycle R-HSA-8980692
RHOU GTPase cycle R-HSA-9013420
Activated NTRK2 signals through PI3K R-HSA-9028335
RET signaling R-HSA-8853659
Nervous system development R-HSA-9675108
Cell-Cell communication R-HSA-1500931
Intracellular signaling by second messengers R-HSA-9006925
Metabolism of lipids R-HSA-556833
FLT3 signaling in disease R-HSA-9682385
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by FGFR2 R-HSA-5654738
Adaptive Immune System R-HSA-1280218
GPCR downstream signalling R-HSA-388396
Downstream TCR signaling R-HSA-202424
GAB1 signalosome R-HSA-180292
DAP12 signaling R-HSA-2424491
RND2 GTPase cycle R-HSA-9696270
Signaling by FGFR1 in disease R-HSA-5655302
Signaling by Insulin receptor R-HSA-74752
Signaling by ERBB4 R-HSA-1236394
Signaling by FGFR3 in disease R-HSA-5655332
Developmental Biology R-HSA-1266738
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FLT3 fusion proteins R-HSA-9703465
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
PI3K/AKT Signaling in Cancer R-HSA-2219528
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Metabolism R-HSA-1430728
Signaling by ERBB2 KD Mutants R-HSA-9664565
Axon guidance R-HSA-422475
Nephrin family interactions R-HSA-373753
Immune System R-HSA-168256
Costimulation by the CD28 family R-HSA-388841
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
PI-3K cascade:FGFR3 R-HSA-5654710
Disease R-HSA-1643685
TCR signaling R-HSA-202403
VEGFA-VEGFR2 Pathway R-HSA-4420097
Interleukin-7 signaling R-HSA-1266695
Phospholipid metabolism R-HSA-1483257
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by PDGFR in disease R-HSA-9671555
Downstream signaling of activated FGFR2 R-HSA-5654696
DAP12 interactions R-HSA-2172127
Developmental Biology R-HSA-1266738
Constitutive Signaling by EGFRvIII R-HSA-5637810
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Signaling by KIT in disease R-HSA-9669938
Adaptive Immune System R-HSA-1280218
Signaling by FGFR1 in disease R-HSA-5655302
Cell-Cell communication R-HSA-1500931
ESR-mediated signaling R-HSA-8939211
PI3K Cascade R-HSA-109704
Interleukin-2 family signaling R-HSA-451927
RHOV GTPase cycle R-HSA-9013424
RHOU GTPase cycle R-HSA-9013420
Negative regulation of the PI3K/AKT network R-HSA-199418
IGF1R signaling cascade R-HSA-2428924
Signaling by FGFR3 R-HSA-5654741
Extra-nuclear estrogen signaling R-HSA-9009391
RHOA GTPase cycle R-HSA-8980692
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
CDC42 GTPase cycle R-HSA-9013148
Signaling by MET R-HSA-6806834
FLT3 Signaling R-HSA-9607240
RAC2 GTPase cycle R-HSA-9013404
PIP3 activates AKT signaling R-HSA-1257604
G alpha (q) signalling events R-HSA-416476
Downstream signaling of activated FGFR3 R-HSA-5654708
PI3K events in ERBB4 signaling R-HSA-1250342
Metabolism of lipids R-HSA-556833
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Signaling by NTRK3 (TRKC) R-HSA-9034015
Interleukin receptor SHC signaling R-HSA-912526
IRS-related events triggered by IGF1R R-HSA-2428928
Signaling by the B Cell Receptor (BCR) R-HSA-983705
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by PDGF R-HSA-186797
DAP12 signaling R-HSA-2424491
Signaling by EGFR R-HSA-177929
Cytokine Signaling in Immune system R-HSA-1280215
RHOF GTPase cycle R-HSA-9035034
Signaling by EGFRvIII in Cancer R-HSA-5637812
Downstream signaling of activated FGFR1 R-HSA-5654687
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
Signaling by NTRKs R-HSA-166520
RND3 GTPase cycle R-HSA-9696264
Activated NTRK2 signals through PI3K R-HSA-9028335
CD28 co-stimulation R-HSA-389356
Signaling by Insulin receptor R-HSA-74752
Signaling by NTRK2 (TRKB) R-HSA-9006115
Downstream signaling of activated FGFR4 R-HSA-5654716
RAC3 GTPase cycle R-HSA-9013423
Signaling by FGFR in disease R-HSA-1226099
Regulation of signaling by CBL R-HSA-912631
Signaling by ERBB2 ECD mutants R-HSA-9665348
Role of phospholipids in phagocytosis R-HSA-2029485
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
CD28 dependent PI3K/Akt signaling R-HSA-389357
Signaling by ALK fusions and activated point mutants R-HSA-9725370
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
Signaling by FGFR4 in disease R-HSA-5655291
Tie2 Signaling R-HSA-210993
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
PI3K events in ERBB2 signaling R-HSA-1963642
RET signaling R-HSA-8853659
MAPK family signaling cascades R-HSA-5683057
RHOC GTPase cycle R-HSA-9013106
Signaling by FGFR R-HSA-190236
Signaling by ERBB2 in Cancer R-HSA-1227990
Signaling by ALK R-HSA-201556
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by FGFR2 R-HSA-5654738
Signaling by ERBB2 R-HSA-1227986
Signaling by Interleukins R-HSA-449147
Innate Immune System R-HSA-168249
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
FLT3 signaling in disease R-HSA-9682385
GPCR downstream signalling R-HSA-388396
MAPK1/MAPK3 signaling R-HSA-5684996
RHOJ GTPase cycle R-HSA-9013409
Signaling by Nuclear Receptors R-HSA-9006931
Signaling by FGFR3 in disease R-HSA-5655332
Platelet activation, signaling and aggregation R-HSA-76002
RHOB GTPase cycle R-HSA-9013026
Hemostasis R-HSA-109582
PI Metabolism R-HSA-1483255
Signaling by SCF-KIT R-HSA-1433557
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Signaling by ALK in cancer R-HSA-9700206
PI3K/AKT activation R-HSA-198203
RAC1 GTPase cycle R-HSA-9013149
Downstream TCR signaling R-HSA-202424
RHO GTPase cycle R-HSA-9012999
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
GP1b-IX-V activation signalling R-HSA-430116
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by ERBB4 R-HSA-1236394
RND2 GTPase cycle R-HSA-9696270
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR2 in disease R-HSA-5655253
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
RHOG GTPase cycle R-HSA-9013408
Signaling by GPCR R-HSA-372790
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Nervous system development R-HSA-9675108
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
MET activates PI3K/AKT signaling R-HSA-8851907
Insulin receptor signalling cascade R-HSA-74751
RHOD GTPase cycle R-HSA-9013405
Signaling by FGFR1 R-HSA-5654736
Synthesis of PIPs at the plasma membrane R-HSA-1660499
PI-3K cascade:FGFR1 R-HSA-5654689
Signal Transduction R-HSA-162582
RND1 GTPase cycle R-HSA-9696273
Cell surface interactions at the vascular wall R-HSA-202733
RAF/MAP kinase cascade R-HSA-5673001
Downstream signal transduction R-HSA-186763
PI-3K cascade:FGFR2 R-HSA-5654695
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
PI-3K cascade:FGFR4 R-HSA-5654720
FGFR1 mutant receptor activation R-HSA-1839124
Signaling by VEGF R-HSA-194138
Signaling by Erythropoietin R-HSA-9006335
IRS-mediated signalling R-HSA-112399
Signaling by Rho GTPases R-HSA-194315
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
GPVI-mediated activation cascade R-HSA-114604
GAB1 signalosome R-HSA-180292
Intracellular signaling by second messengers R-HSA-9006925
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Constitutive Signaling by EGFRvIII R-HSA-5637810
RHOJ GTPase cycle R-HSA-9013409
Axon guidance R-HSA-422475
Signaling by PDGFR in disease R-HSA-9671555
RHOG GTPase cycle R-HSA-9013408
PI-3K cascade:FGFR3 R-HSA-5654710
Interleukin receptor SHC signaling R-HSA-912526
Innate Immune System R-HSA-168249
Signaling by ERBB2 KD Mutants R-HSA-9664565
Signaling by ALK R-HSA-201556
GP1b-IX-V activation signalling R-HSA-430116
RHOD GTPase cycle R-HSA-9013405
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905
Insulin receptor signalling cascade R-HSA-74751
Signaling by KIT in disease R-HSA-9669938
Disease R-HSA-1643685
RHOB GTPase cycle R-HSA-9013026
Downstream signaling of activated FGFR3 R-HSA-5654708
Signaling by FGFR2 R-HSA-5654738
RAC3 GTPase cycle R-HSA-9013423
G alpha (q) signalling events R-HSA-416476
Signaling by NTRK1 (TRKA) R-HSA-187037
Signaling by Interleukins R-HSA-449147
Costimulation by the CD28 family R-HSA-388841
Signaling by FGFR3 R-HSA-5654741
Interleukin-2 family signaling R-HSA-451927
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439
FLT3 signaling in disease R-HSA-9682385
Adaptive Immune System R-HSA-1280218
DAP12 signaling R-HSA-2424491
Signaling by Nuclear Receptors R-HSA-9006931
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530
Signaling by ALK fusions and activated point mutants R-HSA-9725370
PI-3K cascade:FGFR4 R-HSA-5654720
FLT3 Signaling R-HSA-9607240
RND1 GTPase cycle R-HSA-9696273
Nephrin family interactions R-HSA-373753
Activated NTRK2 signals through PI3K R-HSA-9028335
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 R-HSA-9716542
Downstream signaling of activated FGFR2 R-HSA-5654696
Signaling by Rho GTPases R-HSA-194315
Signaling by ERBB4 R-HSA-1236394
IGF1R signaling cascade R-HSA-2428924
RHOA GTPase cycle R-HSA-8980692
PI3K events in ERBB4 signaling R-HSA-1250342
ESR-mediated signaling R-HSA-8939211
Cell surface interactions at the vascular wall R-HSA-202733
RAC2 GTPase cycle R-HSA-9013404
GPCR downstream signalling R-HSA-388396
Signaling by Insulin receptor R-HSA-74752
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767
PI Metabolism R-HSA-1483255
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480
RAC1 GTPase cycle R-HSA-9013149
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling of activated FGFR4 R-HSA-5654716
Tie2 Signaling R-HSA-210993
Signaling by GPCR R-HSA-372790
Metabolism of lipids R-HSA-556833
Signaling by FLT3 fusion proteins R-HSA-9703465
Signaling by FGFR R-HSA-190236
Signaling by PDGF R-HSA-186797
Developmental Biology R-HSA-1266738
Interleukin-7 signaling R-HSA-1266695
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Signaling by FGFR4 R-HSA-5654743
Signaling by FGFR1 R-HSA-5654736
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770
PI3K/AKT activation R-HSA-198203
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Signaling by ERBB2 ECD mutants R-HSA-9665348
Signaling by FGFR3 in disease R-HSA-5655332
Phospholipid metabolism R-HSA-1483257
Signaling by FGFR4 in disease R-HSA-5655291
PI3K/AKT Signaling in Cancer R-HSA-2219528
Downstream signaling of activated FGFR1 R-HSA-5654687
Negative regulation of the PI3K/AKT network R-HSA-199418
CD28 dependent PI3K/Akt signaling R-HSA-389357
Intracellular signaling by second messengers R-HSA-9006925
GPVI-mediated activation cascade R-HSA-114604
Signaling by MET R-HSA-6806834
RHOV GTPase cycle R-HSA-9013424
PI-3K cascade:FGFR2 R-HSA-5654695
Signaling by FGFR2 in disease R-HSA-5655253
Downstream TCR signaling R-HSA-202424
Cell-Cell communication R-HSA-1500931
Signaling by ERBB2 R-HSA-1227986
RHOF GTPase cycle R-HSA-9035034
Signaling by SCF-KIT R-HSA-1433557
Immune System R-HSA-168256
Metabolism R-HSA-1430728
TCR signaling R-HSA-202403
DAP12 interactions R-HSA-2172127
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276
IRS-mediated signalling R-HSA-112399
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by EGFR in Cancer R-HSA-1643713
Signaling by Erythropoietin R-HSA-9006335
RND3 GTPase cycle R-HSA-9696264
Signaling by FGFR in disease R-HSA-1226099
VEGFA-VEGFR2 Pathway R-HSA-4420097
Role of phospholipids in phagocytosis R-HSA-2029485
PI3K Cascade R-HSA-109704
RHO GTPase cycle R-HSA-9012999
Signaling by EGFRvIII in Cancer R-HSA-5637812
Signaling by NTRK3 (TRKC) R-HSA-9034015
MAPK family signaling cascades R-HSA-5683057
RHOU GTPase cycle R-HSA-9013420
FGFR1 mutant receptor activation R-HSA-1839124
Hemostasis R-HSA-109582
Signaling by ERBB2 in Cancer R-HSA-1227990
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695
Signaling by EGFR R-HSA-177929
Extra-nuclear estrogen signaling R-HSA-9009391
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by NTRKs R-HSA-166520
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648
GAB1 signalosome R-HSA-180292
MET activates PI3K/AKT signaling R-HSA-8851907
RHOC GTPase cycle R-HSA-9013106
Regulation of signaling by CBL R-HSA-912631
RND2 GTPase cycle R-HSA-9696270
MAPK1/MAPK3 signaling R-HSA-5684996
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382
Synthesis of PIPs at the plasma membrane R-HSA-1660499
Cytokine Signaling in Immune system R-HSA-1280215
PI3K events in ERBB2 signaling R-HSA-1963642
Nervous system development R-HSA-9675108
CD28 co-stimulation R-HSA-389356
IRS-related events triggered by IGF1R R-HSA-2428928
Downstream signal transduction R-HSA-186763
Signaling by ALK in cancer R-HSA-9700206
RET signaling R-HSA-8853659
PI-3K cascade:FGFR1 R-HSA-5654689
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350
Activated NTRK3 signals through PI3K R-HSA-9603381
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815
Signaling by NTRK2 (TRKB) R-HSA-9006115
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117
Signaling by FGFR1 in disease R-HSA-5655302
CDC42 GTPase cycle R-HSA-9013148
Signaling by VEGF R-HSA-194138
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192
Signaling by Receptor Tyrosine Kinases R-HSA-9006934
Platelet activation, signaling and aggregation R-HSA-76002

Expression Atlas ENSG00000145675
LRG display in Ensembl gene LRG_453
NCBI gene (formerly Entrezgene) 5295
GeneCards 8979
HGNC Symbol HGNC:8979
MIM gene 171833
MIM morbid 616005
UniProtKB Gene Name P27986
WikiGene 5295
Gene: PRKDC
Ensembl ID : ENSG00000253729
Description: protein kinase, DNA-activated, catalytic subunit
Gene Synonyms: DNA-PKC,DNA-PKCS,DNAPK,DNAPKC,DNPK1,HYRC,HYRC1,P350,P460,XRCC7
1 APIs:
187 Possible Orthologues:

Immune System R-HSA-168256
Protein ubiquitination R-HSA-8852135
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Repair R-HSA-73894
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
IRF3-mediated induction of type I IFN R-HSA-3270619
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
Metabolism of proteins R-HSA-392499
STING mediated induction of host immune responses R-HSA-1834941
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Innate Immune System R-HSA-168249
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
IRF3-mediated induction of type I IFN R-HSA-3270619
Metabolism of proteins R-HSA-392499
DNA Double-Strand Break Repair R-HSA-5693532
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Post-translational protein modification R-HSA-597592
DNA Repair R-HSA-73894
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
STING mediated induction of host immune responses R-HSA-1834941
Metabolism of proteins R-HSA-392499
Post-translational protein modification R-HSA-597592
Innate Immune System R-HSA-168249
IRF3-mediated induction of type I IFN R-HSA-3270619
STING mediated induction of host immune responses R-HSA-1834941
DNA Repair R-HSA-73894
Immune System R-HSA-168256
DNA Double-Strand Break Repair R-HSA-5693532
Innate Immune System R-HSA-168249
Post-translational protein modification R-HSA-597592
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
DNA Repair R-HSA-73894
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
IRF3-mediated induction of type I IFN R-HSA-3270619
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
DNA Double-Strand Break Repair R-HSA-5693532
Innate Immune System R-HSA-168249
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
STING mediated induction of host immune responses R-HSA-1834941
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Post-translational protein modification R-HSA-597592
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
STING mediated induction of host immune responses R-HSA-1834941
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
DNA Repair R-HSA-73894
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Innate Immune System R-HSA-168249
DNA Double-Strand Break Repair R-HSA-5693532
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
STING mediated induction of host immune responses R-HSA-1834941
DNA Double-Strand Break Repair R-HSA-5693532
IRF3-mediated induction of type I IFN R-HSA-3270619
Immune System R-HSA-168256
DNA Repair R-HSA-73894
Innate Immune System R-HSA-168249
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
IRF3-mediated induction of type I IFN R-HSA-3270619
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Repair R-HSA-73894
DNA Double-Strand Break Repair R-HSA-5693532
Metabolism of proteins R-HSA-392499
Innate Immune System R-HSA-168249
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135
Post-translational protein modification R-HSA-597592
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Post-translational protein modification R-HSA-597592
STING mediated induction of host immune responses R-HSA-1834941
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
Immune System R-HSA-168256
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
DNA Double-Strand Break Repair R-HSA-5693532
DNA Repair R-HSA-73894
IRF3-mediated induction of type I IFN R-HSA-3270619
Protein ubiquitination R-HSA-8852135
Metabolism of proteins R-HSA-392499
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Innate Immune System R-HSA-168249
DNA Repair R-HSA-73894
Immune System R-HSA-168256
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654
Innate Immune System R-HSA-168249
Metabolism of proteins R-HSA-392499
IRF3-mediated induction of type I IFN R-HSA-3270619
Nonhomologous End-Joining (NHEJ) R-HSA-5693571
Post-translational protein modification R-HSA-597592
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949
DNA Double-Strand Break Repair R-HSA-5693532
STING mediated induction of host immune responses R-HSA-1834941
Protein ubiquitination R-HSA-8852135

Expression Atlas ENSG00000253729
LRG display in Ensembl gene LRG_162
NCBI gene (formerly Entrezgene) 5591
GeneCards 9413
HGNC Symbol HGNC:9413
MIM gene 600899
MIM morbid 615966
UniProtKB Gene Name P78527
WikiGene 5591
Gene: JAK1
Ensembl ID : ENSG00000162434
Description: Janus kinase 1
Gene Synonyms: JAK1A,JAK1B,JTK3
19 APIs:
238 Possible Orthologues:

Disease R-HSA-1643685
Interferon gamma signaling R-HSA-877300
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-21 signaling R-HSA-9020958
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 signaling R-HSA-9020558
Interleukin-9 signaling R-HSA-8985947
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Regulation of IFNA/IFNB signaling R-HSA-912694
Other interleukin signaling R-HSA-449836
Immune System R-HSA-168256
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-2 family signaling R-HSA-451927
Interleukin-12 signaling R-HSA-9020591
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-35 Signalling R-HSA-8984722
MAPK3 (ERK1) activation R-HSA-110056
Signal Transduction R-HSA-162582
Interleukin-27 signaling R-HSA-9020956
Interleukin-7 signaling R-HSA-1266695
Interleukin-10 signaling R-HSA-6783783
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
MAPK family signaling cascades R-HSA-5683057
Infectious disease R-HSA-5663205
Interleukin-6 signaling R-HSA-1059683
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-15 signaling R-HSA-8983432
Regulation of IFNG signaling R-HSA-877312
Interleukin receptor SHC signaling R-HSA-912526
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-2 Infection R-HSA-9694516
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
SARS-CoV-2-host interactions R-HSA-9705683
Interferon Signaling R-HSA-913531
Interferon alpha/beta signaling R-HSA-909733
Signaling by Interleukins R-HSA-449147
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interleukin-12 family signaling R-HSA-447115
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interleukin-6 family signaling R-HSA-6783589
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-20 family signaling R-HSA-8854691
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-12 signaling R-HSA-9020591
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Regulation of IFNG signaling R-HSA-877312
Interferon gamma signaling R-HSA-877300
Disease R-HSA-1643685
Interleukin-7 signaling R-HSA-1266695
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
MAPK1 (ERK2) activation R-HSA-112411
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Other interleukin signaling R-HSA-449836
Immune System R-HSA-168256
ISG15 antiviral mechanism R-HSA-1169408
MAPK family signaling cascades R-HSA-5683057
SARS-CoV-2 Infection R-HSA-9694516
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-2 family signaling R-HSA-451927
Interleukin-6 signaling R-HSA-1059683
RAF-independent MAPK1/3 activation R-HSA-112409
SARS-CoV-2-host interactions R-HSA-9705683
Signaling by Interleukins R-HSA-449147
Interleukin-21 signaling R-HSA-9020958
Interleukin-12 family signaling R-HSA-447115
Interferon Signaling R-HSA-913531
Interleukin-35 Signalling R-HSA-8984722
Interleukin-6 family signaling R-HSA-6783589
Interleukin-27 signaling R-HSA-9020956
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
SARS-CoV Infections R-HSA-9679506
Interleukin-9 signaling R-HSA-8985947
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-2 signaling R-HSA-9020558
MAPK3 (ERK1) activation R-HSA-110056
Regulation of IFNA/IFNB signaling R-HSA-912694
Interleukin receptor SHC signaling R-HSA-912526
Signal Transduction R-HSA-162582
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-15 signaling R-HSA-8983432
Interleukin-10 signaling R-HSA-6783783
Infectious disease R-HSA-5663205
Potential therapeutics for SARS R-HSA-9679191
Interleukin-20 family signaling R-HSA-8854691
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interferon alpha/beta signaling R-HSA-909733
Interferon gamma signaling R-HSA-877300
Interleukin-10 signaling R-HSA-6783783
MAPK1/MAPK3 signaling R-HSA-5684996
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Potential therapeutics for SARS R-HSA-9679191
MAPK3 (ERK1) activation R-HSA-110056
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interferon Signaling R-HSA-913531
Interleukin-35 Signalling R-HSA-8984722
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Signal Transduction R-HSA-162582
Regulation of IFNA/IFNB signaling R-HSA-912694
ISG15 antiviral mechanism R-HSA-1169408
Infectious disease R-HSA-5663205
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
SARS-CoV-2-host interactions R-HSA-9705683
Interleukin-15 signaling R-HSA-8983432
Interferon alpha/beta signaling R-HSA-909733
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-7 signaling R-HSA-1266695
Signaling by Interleukins R-HSA-449147
Interleukin-12 signaling R-HSA-9020591
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Signaling by CSF3 (G-CSF) R-HSA-9674555
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-6 family signaling R-HSA-6783589
Interleukin-9 signaling R-HSA-8985947
Immune System R-HSA-168256
Interleukin-21 signaling R-HSA-9020958
Disease R-HSA-1643685
Interleukin-6 signaling R-HSA-1059683
Regulation of IFNG signaling R-HSA-877312
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
SARS-CoV Infections R-HSA-9679506
MAPK family signaling cascades R-HSA-5683057
Interleukin-20 family signaling R-HSA-8854691
Interleukin-12 family signaling R-HSA-447115
Interleukin-2 signaling R-HSA-9020558
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-27 signaling R-HSA-9020956
Interleukin-2 family signaling R-HSA-451927
MAPK1 (ERK2) activation R-HSA-112411
Other interleukin signaling R-HSA-449836
Interleukin-35 Signalling R-HSA-8984722
Signaling by CSF3 (G-CSF) R-HSA-9674555
Immune System R-HSA-168256
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
ISG15 antiviral mechanism R-HSA-1169408
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-20 family signaling R-HSA-8854691
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-15 signaling R-HSA-8983432
Interleukin-6 family signaling R-HSA-6783589
Potential therapeutics for SARS R-HSA-9679191
Interleukin-21 signaling R-HSA-9020958
Regulation of IFNA/IFNB signaling R-HSA-912694
Infectious disease R-HSA-5663205
RAF-independent MAPK1/3 activation R-HSA-112409
SARS-CoV Infections R-HSA-9679506
Interleukin-27 signaling R-HSA-9020956
Interleukin-12 family signaling R-HSA-447115
Interleukin-6 signaling R-HSA-1059683
Signal Transduction R-HSA-162582
Interleukin-2 signaling R-HSA-9020558
Interferon alpha/beta signaling R-HSA-909733
Interleukin-10 signaling R-HSA-6783783
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Regulation of IFNG signaling R-HSA-877312
MAPK1/MAPK3 signaling R-HSA-5684996
Cytokine Signaling in Immune system R-HSA-1280215
SARS-CoV-2-host interactions R-HSA-9705683
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Disease R-HSA-1643685
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-7 signaling R-HSA-1266695
MAPK family signaling cascades R-HSA-5683057
Signaling by Interleukins R-HSA-449147
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-12 signaling R-HSA-9020591
Interleukin receptor SHC signaling R-HSA-912526
Other interleukin signaling R-HSA-449836
Interleukin-9 signaling R-HSA-8985947
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-2 family signaling R-HSA-451927
Interferon Signaling R-HSA-913531
Interferon gamma signaling R-HSA-877300
Interleukin-15 signaling R-HSA-8983432
Infectious disease R-HSA-5663205
Interleukin-7 signaling R-HSA-1266695
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-6 signaling R-HSA-1059683
RAF/MAP kinase cascade R-HSA-5673001
Interferon gamma signaling R-HSA-877300
Interleukin-12 family signaling R-HSA-447115
Regulation of IFNG signaling R-HSA-877312
SARS-CoV-2-host interactions R-HSA-9705683
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interferon Signaling R-HSA-913531
Interleukin-2 signaling R-HSA-9020558
Regulation of IFNA/IFNB signaling R-HSA-912694
Other interleukin signaling R-HSA-449836
Interleukin-21 signaling R-HSA-9020958
Signaling by Interleukins R-HSA-449147
Disease R-HSA-1643685
Interleukin-10 signaling R-HSA-6783783
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interleukin-20 family signaling R-HSA-8854691
Interleukin-6 family signaling R-HSA-6783589
SARS-CoV Infections R-HSA-9679506
Immune System R-HSA-168256
Interleukin-9 signaling R-HSA-8985947
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin receptor SHC signaling R-HSA-912526
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-27 signaling R-HSA-9020956
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Interleukin-12 signaling R-HSA-9020591
MAPK3 (ERK1) activation R-HSA-110056
Potential therapeutics for SARS R-HSA-9679191
Interleukin-2 family signaling R-HSA-451927
Interleukin-35 Signalling R-HSA-8984722
Signal Transduction R-HSA-162582
MAPK1 (ERK2) activation R-HSA-112411
MAPK family signaling cascades R-HSA-5683057
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
ISG15 antiviral mechanism R-HSA-1169408
Interferon alpha/beta signaling R-HSA-909733
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interferon alpha/beta signaling R-HSA-909733
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Regulation of IFNG signaling R-HSA-877312
Immune System R-HSA-168256
Regulation of IFNA/IFNB signaling R-HSA-912694
Interferon gamma signaling R-HSA-877300
Disease R-HSA-1643685
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-2 family signaling R-HSA-451927
Signal Transduction R-HSA-162582
MAPK1 (ERK2) activation R-HSA-112411
Interferon Signaling R-HSA-913531
SARS-CoV-2 Infection R-HSA-9694516
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-6 signaling R-HSA-1059683
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-10 signaling R-HSA-6783783
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interleukin-15 signaling R-HSA-8983432
Interleukin-35 Signalling R-HSA-8984722
Interleukin-12 signaling R-HSA-9020591
MAPK family signaling cascades R-HSA-5683057
Interleukin-6 family signaling R-HSA-6783589
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-12 family signaling R-HSA-447115
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Interleukin-21 signaling R-HSA-9020958
Interleukin-9 signaling R-HSA-8985947
SARS-CoV-2-host interactions R-HSA-9705683
MAPK1/MAPK3 signaling R-HSA-5684996
Interleukin-20 family signaling R-HSA-8854691
Interleukin receptor SHC signaling R-HSA-912526
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Potential therapeutics for SARS R-HSA-9679191
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Signaling by Interleukins R-HSA-449147
RAF/MAP kinase cascade R-HSA-5673001
Infectious disease R-HSA-5663205
Other interleukin signaling R-HSA-449836
Interleukin-27 signaling R-HSA-9020956
Interleukin-2 signaling R-HSA-9020558
Interleukin-7 signaling R-HSA-1266695
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interleukin-20 family signaling R-HSA-8854691
Signaling by CSF3 (G-CSF) R-HSA-9674555
SARS-CoV-2 Infection R-HSA-9694516
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Interferon alpha/beta signaling R-HSA-909733
MAPK family signaling cascades R-HSA-5683057
Interleukin-2 family signaling R-HSA-451927
SARS-CoV-2-host interactions R-HSA-9705683
Signal Transduction R-HSA-162582
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-7 signaling R-HSA-1266695
Interleukin-10 signaling R-HSA-6783783
Interleukin-21 signaling R-HSA-9020958
Interleukin receptor SHC signaling R-HSA-912526
MAPK1/MAPK3 signaling R-HSA-5684996
Disease R-HSA-1643685
Regulation of IFNG signaling R-HSA-877312
Interleukin-15 signaling R-HSA-8983432
Other interleukin signaling R-HSA-449836
Signaling by Interleukins R-HSA-449147
Interleukin-2 signaling R-HSA-9020558
Interferon Signaling R-HSA-913531
MAPK3 (ERK1) activation R-HSA-110056
SARS-CoV Infections R-HSA-9679506
Interleukin-9 signaling R-HSA-8985947
Interleukin-12 signaling R-HSA-9020591
Interferon gamma signaling R-HSA-877300
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interleukin-6 family signaling R-HSA-6783589
Infectious disease R-HSA-5663205
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-35 Signalling R-HSA-8984722
Immune System R-HSA-168256
Regulation of IFNA/IFNB signaling R-HSA-912694
MAPK1 (ERK2) activation R-HSA-112411
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
RAF/MAP kinase cascade R-HSA-5673001
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-6 signaling R-HSA-1059683
Potential therapeutics for SARS R-HSA-9679191
Interleukin-12 family signaling R-HSA-447115
Interleukin-27 signaling R-HSA-9020956
Cytokine Signaling in Immune system R-HSA-1280215
Cytokine Signaling in Immune system R-HSA-1280215
Interleukin-21 signaling R-HSA-9020958
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
Interleukin-2 family signaling R-HSA-451927
Interleukin-7 signaling R-HSA-1266695
Signaling by CSF3 (G-CSF) R-HSA-9674555
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Interleukin-35 Signalling R-HSA-8984722
MAPK1/MAPK3 signaling R-HSA-5684996
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Immune System R-HSA-168256
Interleukin-20 family signaling R-HSA-8854691
Regulation of IFNG signaling R-HSA-877312
SARS-CoV-2 Infection R-HSA-9694516
MAPK3 (ERK1) activation R-HSA-110056
RAF-independent MAPK1/3 activation R-HSA-112409
Interleukin-9 signaling R-HSA-8985947
Other interleukin signaling R-HSA-449836
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interleukin-6 family signaling R-HSA-6783589
MAPK family signaling cascades R-HSA-5683057
MAPK1 (ERK2) activation R-HSA-112411
Interleukin receptor SHC signaling R-HSA-912526
Signaling by Interleukins R-HSA-449147
Signal Transduction R-HSA-162582
SARS-CoV Infections R-HSA-9679506
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-12 family signaling R-HSA-447115
Disease R-HSA-1643685
Interferon gamma signaling R-HSA-877300
Infectious disease R-HSA-5663205
Interferon Signaling R-HSA-913531
Interleukin-12 signaling R-HSA-9020591
Potential therapeutics for SARS R-HSA-9679191
Interleukin-27 signaling R-HSA-9020956
Regulation of IFNA/IFNB signaling R-HSA-912694
Interferon alpha/beta signaling R-HSA-909733
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-10 signaling R-HSA-6783783
RAF/MAP kinase cascade R-HSA-5673001
Interleukin-6 signaling R-HSA-1059683
Interleukin-2 signaling R-HSA-9020558
SARS-CoV-2-host interactions R-HSA-9705683
Interleukin-15 signaling R-HSA-8983432
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-7 signaling R-HSA-1266695
Immune System R-HSA-168256
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
RAF/MAP kinase cascade R-HSA-5673001
MAPK1/MAPK3 signaling R-HSA-5684996
SARS-CoV-2-host interactions R-HSA-9705683
Potential therapeutics for SARS R-HSA-9679191
Interleukin-27 signaling R-HSA-9020956
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
Interleukin-20 family signaling R-HSA-8854691
Interleukin-15 signaling R-HSA-8983432
Interleukin-2 family signaling R-HSA-451927
Interleukin-10 signaling R-HSA-6783783
SARS-CoV Infections R-HSA-9679506
Interleukin-2 signaling R-HSA-9020558
Interleukin-35 Signalling R-HSA-8984722
Regulation of IFNG signaling R-HSA-877312
Signal Transduction R-HSA-162582
Interleukin-21 signaling R-HSA-9020958
Disease R-HSA-1643685
Interleukin-6 family signaling R-HSA-6783589
Interferon Signaling R-HSA-913531
RAF-independent MAPK1/3 activation R-HSA-112409
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
MAPK1 (ERK2) activation R-HSA-112411
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of IFNA/IFNB signaling R-HSA-912694
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
SARS-CoV-2 Infection R-HSA-9694516
Interleukin-6 signaling R-HSA-1059683
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
MAPK family signaling cascades R-HSA-5683057
Interferon alpha/beta signaling R-HSA-909733
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin receptor SHC signaling R-HSA-912526
Infectious disease R-HSA-5663205
Interleukin-12 signaling R-HSA-9020591
MAPK3 (ERK1) activation R-HSA-110056
Interleukin-12 family signaling R-HSA-447115
Interleukin-9 signaling R-HSA-8985947
Signaling by Interleukins R-HSA-449147
Other interleukin signaling R-HSA-449836
Interferon gamma signaling R-HSA-877300
Infectious disease R-HSA-5663205
Interleukin-9 signaling R-HSA-8985947
Interferon Signaling R-HSA-913531
Disease R-HSA-1643685
Interleukin-6 signaling R-HSA-1059683
MAPK1 (ERK2) activation R-HSA-112411
RAF-independent MAPK1/3 activation R-HSA-112409
Other interleukin signaling R-HSA-449836
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807
RAF/MAP kinase cascade R-HSA-5673001
Signaling by CSF3 (G-CSF) R-HSA-9674555
Interleukin-12 family signaling R-HSA-447115
MAPK family signaling cascades R-HSA-5683057
Immune System R-HSA-168256
Interleukin receptor SHC signaling R-HSA-912526
SARS-CoV-2-host interactions R-HSA-9705683
Regulation of IFNG signaling R-HSA-877312
Interleukin-2 family signaling R-HSA-451927
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671
Regulation of IFNA/IFNB signaling R-HSA-912694
Interleukin-10 signaling R-HSA-6783783
MAPK1/MAPK3 signaling R-HSA-5684996
Interferon gamma signaling R-HSA-877300
Interleukin-20 family signaling R-HSA-8854691
Signaling by Interleukins R-HSA-449147
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462
Interleukin-27 signaling R-HSA-9020956
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410
Interferon alpha/beta signaling R-HSA-909733
Interleukin-15 signaling R-HSA-8983432
Interleukin-2 signaling R-HSA-9020558
Interleukin-21 signaling R-HSA-9020958
MAPK3 (ERK1) activation R-HSA-110056
Cytokine Signaling in Immune system R-HSA-1280215
IL-6-type cytokine receptor ligand interactions R-HSA-6788467
ISG15 antiviral mechanism R-HSA-1169408
Interleukin-7 signaling R-HSA-1266695
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988
SARS-CoV Infections R-HSA-9679506
Interleukin-35 Signalling R-HSA-8984722
Potential therapeutics for SARS R-HSA-9679191
SARS-CoV-2 Infection R-HSA-9694516
Signal Transduction R-HSA-162582
Interleukin-6 family signaling R-HSA-6783589
Interleukin-12 signaling R-HSA-9020591

Expression Atlas ENSG00000162434
LRG display in Ensembl gene LRG_1398
NCBI gene (formerly Entrezgene) 3716
GeneCards 6190
HGNC Symbol HGNC:6190
MIM gene 147795
MIM morbid 618999
UniProtKB Gene Name P23458
WikiGene 3716
Gene: CDC7
Ensembl ID : ENSG00000097046
Description: cell division cycle 7
Gene Synonyms: CDC7L1,HSCDC7,HSK1,HUCDC7
4 APIs:
209 Possible Orthologues:

DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Activation of ATR in response to replication stress R-HSA-176187
Transcriptional Regulation by E2F6 R-HSA-8953750
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
G2/M Checkpoints R-HSA-69481
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
Cell Cycle, Mitotic R-HSA-69278
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle, Mitotic R-HSA-69278
Transcriptional Regulation by E2F6 R-HSA-8953750
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
G1/S Transition R-HSA-69206
Generic Transcription Pathway R-HSA-212436
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
DNA Replication R-HSA-69306
Transcriptional Regulation by E2F6 R-HSA-8953750
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Mitotic G1 phase and G1/S transition R-HSA-453279
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional Regulation by E2F6 R-HSA-8953750
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Cell Cycle Checkpoints R-HSA-69620
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Cell Cycle R-HSA-1640170
Transcriptional Regulation by E2F6 R-HSA-8953750
Cell Cycle Checkpoints R-HSA-69620
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Activation of the pre-replicative complex R-HSA-68962
Activation of ATR in response to replication stress R-HSA-176187
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Generic Transcription Pathway R-HSA-212436
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
Activation of ATR in response to replication stress R-HSA-176187
DNA Replication R-HSA-69306
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
Transcriptional Regulation by E2F6 R-HSA-8953750
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
Mitotic G1 phase and G1/S transition R-HSA-453279
Generic Transcription Pathway R-HSA-212436
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
G2/M Checkpoints R-HSA-69481
DNA Replication Pre-Initiation R-HSA-69002
Activation of ATR in response to replication stress R-HSA-176187
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
Cell Cycle, Mitotic R-HSA-69278
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by E2F6 R-HSA-8953750
Gene expression (Transcription) R-HSA-74160
Cell Cycle Checkpoints R-HSA-69620
G2/M Checkpoints R-HSA-69481
Transcriptional Regulation by E2F6 R-HSA-8953750
Activation of ATR in response to replication stress R-HSA-176187
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
DNA Replication R-HSA-69306
Cell Cycle Checkpoints R-HSA-69620
G1/S Transition R-HSA-69206
Cell Cycle, Mitotic R-HSA-69278
Activation of the pre-replicative complex R-HSA-68962
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle R-HSA-1640170
Gene expression (Transcription) R-HSA-74160
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle, Mitotic R-HSA-69278
Activation of ATR in response to replication stress R-HSA-176187
DNA Replication R-HSA-69306
Activation of the pre-replicative complex R-HSA-68962
Cell Cycle Checkpoints R-HSA-69620
RNA Polymerase II Transcription R-HSA-73857
G2/M Checkpoints R-HSA-69481
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle R-HSA-1640170
DNA Replication Pre-Initiation R-HSA-69002
Transcriptional Regulation by E2F6 R-HSA-8953750
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
G1/S Transition R-HSA-69206
Cell Cycle R-HSA-1640170
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
RNA Polymerase II Transcription R-HSA-73857
Transcriptional Regulation by E2F6 R-HSA-8953750
Activation of the pre-replicative complex R-HSA-68962
G1/S Transition R-HSA-69206
Mitotic G1 phase and G1/S transition R-HSA-453279
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Gene expression (Transcription) R-HSA-74160
Cell Cycle, Mitotic R-HSA-69278
G2/M Checkpoints R-HSA-69481
Activation of ATR in response to replication stress R-HSA-176187
Mitotic G1 phase and G1/S transition R-HSA-453279
G1/S Transition R-HSA-69206
Transcriptional Regulation by E2F6 R-HSA-8953750
DNA Replication R-HSA-69306
DNA Replication Pre-Initiation R-HSA-69002
Cell Cycle, Mitotic R-HSA-69278
Cell Cycle Checkpoints R-HSA-69620
Generic Transcription Pathway R-HSA-212436
Cell Cycle R-HSA-1640170
Activation of ATR in response to replication stress R-HSA-176187
Activation of the pre-replicative complex R-HSA-68962
G2/M Checkpoints R-HSA-69481
RNA Polymerase II Transcription R-HSA-73857
Gene expression (Transcription) R-HSA-74160

Expression Atlas ENSG00000097046
NCBI gene (formerly Entrezgene) 8317
GeneCards 1745
HGNC Symbol HGNC:1745
MIM gene 603311
UniProtKB Gene Name O00311
WikiGene 8317
Gene: PSMC5
Ensembl ID : ENSG00000087191
Description: proteasome 26S subunit, ATPase 5
Gene Synonyms: P45,P45/SUG,RPT6,S8,SUG-1,SUG1,TBP10,TRIP1
5 APIs:
219 Possible Orthologues:

G1/S Transition R-HSA-69206
G2/M Checkpoints R-HSA-69481
Hedgehog 'on' state R-HSA-5632684
S Phase R-HSA-69242
Degradation of DVL R-HSA-4641258
Signaling by NOTCH R-HSA-157118
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
TCR signaling R-HSA-202403
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
MAPK family signaling cascades R-HSA-5683057
UCH proteinases R-HSA-5689603
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Deubiquitination R-HSA-5688426
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Metabolism of amino acids and derivatives R-HSA-71291
Nervous system development R-HSA-9675108
Signal Transduction R-HSA-162582
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular responses to stimuli R-HSA-8953897
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
ABC-family proteins mediated transport R-HSA-382556
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle, Mitotic R-HSA-69278
Cytokine Signaling in Immune system R-HSA-1280215
Generic Transcription Pathway R-HSA-212436
Degradation of DVL R-HSA-4641258
Post-translational protein modification R-HSA-597592
Cellular response to hypoxia R-HSA-1234174
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Neddylation R-HSA-8951664
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Degradation of GLI1 by the proteasome R-HSA-5610780
G2/M Transition R-HSA-69275
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Regulation of Apoptosis R-HSA-169911
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
MAPK6/MAPK4 signaling R-HSA-5687128
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH4 R-HSA-9013694
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Regulation of PTEN stability and activity R-HSA-8948751
Interleukin-1 family signaling R-HSA-446652
Cell Cycle R-HSA-1640170
Programmed Cell Death R-HSA-5357801
Regulation of RAS by GAPs R-HSA-5658442
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hedgehog 'on' state R-HSA-5632684
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Signaling by ROBO receptors R-HSA-376176
Mitotic Anaphase R-HSA-68882
Regulation of RUNX3 expression and activity R-HSA-8941858
Negative regulation of NOTCH4 signaling R-HSA-9604323
DNA Replication R-HSA-69306
Degradation of AXIN R-HSA-4641257
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX3 R-HSA-8878159
Regulation of RUNX2 expression and activity R-HSA-8939902
Beta-catenin independent WNT signaling R-HSA-3858494
Apoptosis R-HSA-109581
p53-Independent DNA Damage Response R-HSA-69610
Degradation of beta-catenin by the destruction complex R-HSA-195253
Gene expression (Transcription) R-HSA-74160
Signaling by Hedgehog R-HSA-5358351
Cyclin E associated events during G1/S transition R-HSA-69202
Assembly of the pre-replicative complex R-HSA-68867
Interleukin-1 signaling R-HSA-9020702
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Hedgehog ligand biogenesis R-HSA-5358346
Signaling by the B Cell Receptor (BCR) R-HSA-983705
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Cellular response to chemical stress R-HSA-9711123
Orc1 removal from chromatin R-HSA-68949
Metabolism of RNA R-HSA-8953854
Transcriptional regulation by RUNX2 R-HSA-8878166
PIP3 activates AKT signaling R-HSA-1257604
Hh mutants are degraded by ERAD R-HSA-5362768
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
ABC transporter disorders R-HSA-5619084
ER-Phagosome pathway R-HSA-1236974
MAPK1/MAPK3 signaling R-HSA-5684996
Host Interactions of HIV factors R-HSA-162909
Axon guidance R-HSA-422475
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Checkpoints R-HSA-69481
Vif-mediated degradation of APOBEC3G R-HSA-180585
Cellular responses to stress R-HSA-2262752
HIV Infection R-HSA-162906
Degradation of GLI2 by the proteasome R-HSA-5610783
Signaling by NOTCH R-HSA-157118
Stabilization of p53 R-HSA-69541
Immune System R-HSA-168256
Metabolism of proteins R-HSA-392499
Developmental Biology R-HSA-1266738
Innate Immune System R-HSA-168249
Synthesis of DNA R-HSA-69239
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants abrogate ligand secretion R-HSA-5387390
S Phase R-HSA-69242
KEAP1-NFE2L2 pathway R-HSA-9755511
Defective CFTR causes cystic fibrosis R-HSA-5678895
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Antigen processing-Cross presentation R-HSA-1236975
Cell Cycle Checkpoints R-HSA-69620
Adaptive Immune System R-HSA-1280218
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
Switching of origins to a post-replicative state R-HSA-69052
G1/S DNA Damage Checkpoints R-HSA-69615
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Asymmetric localization of PCP proteins R-HSA-4608870
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
DNA Replication Pre-Initiation R-HSA-69002
Infectious disease R-HSA-5663205
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
Activation of NF-kappaB in B cells R-HSA-1169091
Intracellular signaling by second messengers R-HSA-9006925
RAF/MAP kinase cascade R-HSA-5673001
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Nuclear events mediated by NFE2L2 R-HSA-9759194
Vpu mediated degradation of CD4 R-HSA-180534
Mitotic G1 phase and G1/S transition R-HSA-453279
Transport of small molecules R-HSA-382551
Downstream TCR signaling R-HSA-202424
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Metabolism of polyamines R-HSA-351202
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ub-specific processing proteases R-HSA-5689880
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
CLEC7A (Dectin-1) signaling R-HSA-5607764
Signaling by Interleukins R-HSA-449147
RNA Polymerase II Transcription R-HSA-73857
Separation of Sister Chromatids R-HSA-2467813
Mitotic G2-G2/M phases R-HSA-453274
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Hedgehog 'off' state R-HSA-5610787
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Class I MHC mediated antigen processing & presentation R-HSA-983169
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Deubiquitination R-HSA-5688426
Programmed Cell Death R-HSA-5357801
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Degradation of GLI2 by the proteasome R-HSA-5610783
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Signaling by Interleukins R-HSA-449147
HIV Infection R-HSA-162906
Regulation of RUNX2 expression and activity R-HSA-8939902
Metabolism R-HSA-1430728
Ub-specific processing proteases R-HSA-5689880
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Hedgehog 'off' state R-HSA-5610787
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cell Cycle R-HSA-1640170
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Defective CFTR causes cystic fibrosis R-HSA-5678895
C-type lectin receptors (CLRs) R-HSA-5621481
Hedgehog ligand biogenesis R-HSA-5358346
Transport of small molecules R-HSA-382551
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Cyclin E associated events during G1/S transition R-HSA-69202
Vpu mediated degradation of CD4 R-HSA-180534
Hh mutants abrogate ligand secretion R-HSA-5387390
Downstream TCR signaling R-HSA-202424
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Transcriptional regulation by RUNX1 R-HSA-8878171
TCR signaling R-HSA-202403
Synthesis of DNA R-HSA-69239
Signaling by NOTCH R-HSA-157118
Cellular responses to stress R-HSA-2262752
FCERI mediated NF-kB activation R-HSA-2871837
Beta-catenin independent WNT signaling R-HSA-3858494
Neddylation R-HSA-8951664
CLEC7A (Dectin-1) signaling R-HSA-5607764
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Transcriptional regulation by RUNX3 R-HSA-8878159
Gene expression (Transcription) R-HSA-74160
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Post-translational protein modification R-HSA-597592
p53-Dependent G1 DNA Damage Response R-HSA-69563
PCP/CE pathway R-HSA-4086400
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
DNA Replication R-HSA-69306
G2/M Transition R-HSA-69275
Stabilization of p53 R-HSA-69541
Signaling by WNT R-HSA-195721
Asymmetric localization of PCP proteins R-HSA-4608870
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Assembly of the pre-replicative complex R-HSA-68867
Antigen processing-Cross presentation R-HSA-1236975
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of AXIN R-HSA-4641257
Disorders of transmembrane transporters R-HSA-5619115
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Separation of Sister Chromatids R-HSA-2467813
Metabolism of amino acids and derivatives R-HSA-71291
G2/M Checkpoints R-HSA-69481
G1/S DNA Damage Checkpoints R-HSA-69615
Intracellular signaling by second messengers R-HSA-9006925
Regulation of expression of SLITs and ROBOs R-HSA-9010553
MAPK family signaling cascades R-HSA-5683057
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of mitotic cell cycle R-HSA-453276
M Phase R-HSA-68886
RAF/MAP kinase cascade R-HSA-5673001
Signaling by Hedgehog R-HSA-5358351
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Degradation of GLI1 by the proteasome R-HSA-5610780
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Disease R-HSA-1643685
KEAP1-NFE2L2 pathway R-HSA-9755511
Orc1 removal from chromatin R-HSA-68949
UCH proteinases R-HSA-5689603
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
MAPK6/MAPK4 signaling R-HSA-5687128
Metabolism of RNA R-HSA-8953854
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Cellular response to hypoxia R-HSA-1234174
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Hedgehog 'on' state R-HSA-5632684
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
ABC-family proteins mediated transport R-HSA-382556
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
Activation of NF-kappaB in B cells R-HSA-1169091
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Cellular responses to stimuli R-HSA-8953897
ER-Phagosome pathway R-HSA-1236974
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Switching of origins to a post-replicative state R-HSA-69052
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Mitotic Anaphase R-HSA-68882
RNA Polymerase II Transcription R-HSA-73857
Interleukin-1 family signaling R-HSA-446652
Mitotic Metaphase and Anaphase R-HSA-2555396
Cell Cycle Checkpoints R-HSA-69620
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Adaptive Immune System R-HSA-1280218
Vif-mediated degradation of APOBEC3G R-HSA-180585
Apoptosis R-HSA-109581
G1/S Transition R-HSA-69206
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Signaling by ROBO receptors R-HSA-376176
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of Apoptosis R-HSA-169911
Regulation of RUNX3 expression and activity R-HSA-8941858
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Cellular response to chemical stress R-HSA-9711123
Interleukin-1 signaling R-HSA-9020702
ABC transporter disorders R-HSA-5619084
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of PTEN stability and activity R-HSA-8948751
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by NOTCH4 R-HSA-9013694
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Axon guidance R-HSA-422475
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Developmental Biology R-HSA-1266738
Host Interactions of HIV factors R-HSA-162909
Mitotic G2-G2/M phases R-HSA-453274
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Mitotic G1 phase and G1/S transition R-HSA-453279
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
PIP3 activates AKT signaling R-HSA-1257604
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Degradation of DVL R-HSA-4641258
Nervous system development R-HSA-9675108
p53-Independent DNA Damage Response R-HSA-69610
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
ABC-family proteins mediated transport R-HSA-382556
Infectious disease R-HSA-5663205
Metabolism R-HSA-1430728
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Regulation of RUNX3 expression and activity R-HSA-8941858
Disease R-HSA-1643685
Transport of small molecules R-HSA-382551
Mitotic Metaphase and Anaphase R-HSA-2555396
ABC transporter disorders R-HSA-5619084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Innate Immune System R-HSA-168249
G2/M Checkpoints R-HSA-69481
Hh mutants are degraded by ERAD R-HSA-5362768
Cellular response to chemical stress R-HSA-9711123
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Regulation of RAS by GAPs R-HSA-5658442
RAF/MAP kinase cascade R-HSA-5673001
p53-Dependent G1 DNA Damage Response R-HSA-69563
Signaling by WNT R-HSA-195721
Stabilization of p53 R-HSA-69541
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Activation of NF-kappaB in B cells R-HSA-1169091
Axon guidance R-HSA-422475
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Hedgehog ligand biogenesis R-HSA-5358346
Cytokine Signaling in Immune system R-HSA-1280215
Vpu mediated degradation of CD4 R-HSA-180534
Cell Cycle R-HSA-1640170
Signaling by NOTCH4 R-HSA-9013694
Transcriptional regulation by RUNX2 R-HSA-8878166
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
RNA Polymerase II Transcription R-HSA-73857
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
CLEC7A (Dectin-1) signaling R-HSA-5607764
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G1/S DNA Damage Checkpoints R-HSA-69615
MAPK1/MAPK3 signaling R-HSA-5684996
Downstream TCR signaling R-HSA-202424
Immune System R-HSA-168256
Degradation of beta-catenin by the destruction complex R-HSA-195253
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
MAPK family signaling cascades R-HSA-5683057
Nervous system development R-HSA-9675108
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cyclin E associated events during G1/S transition R-HSA-69202
Disorders of transmembrane transporters R-HSA-5619115
Regulation of mitotic cell cycle R-HSA-453276
Developmental Biology R-HSA-1266738
Hedgehog 'off' state R-HSA-5610787
Adaptive Immune System R-HSA-1280218
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
PCP/CE pathway R-HSA-4086400
Assembly of the pre-replicative complex R-HSA-68867
Signaling by Interleukins R-HSA-449147
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog 'on' state R-HSA-5632684
UCH proteinases R-HSA-5689603
MAPK6/MAPK4 signaling R-HSA-5687128
p53-Independent DNA Damage Response R-HSA-69610
TCR signaling R-HSA-202403
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Generic Transcription Pathway R-HSA-212436
Deubiquitination R-HSA-5688426
Cellular responses to stress R-HSA-2262752
Beta-catenin independent WNT signaling R-HSA-3858494
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Transcriptional regulation by RUNX3 R-HSA-8878159
HIV Infection R-HSA-162906
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Metabolism of polyamines R-HSA-351202
Cell Cycle Checkpoints R-HSA-69620
Defective CFTR causes cystic fibrosis R-HSA-5678895
Neddylation R-HSA-8951664
Signaling by NOTCH R-HSA-157118
Degradation of AXIN R-HSA-4641257
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Metabolism of RNA R-HSA-8953854
Signaling by Hedgehog R-HSA-5358351
Separation of Sister Chromatids R-HSA-2467813
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Programmed Cell Death R-HSA-5357801
Regulation of PTEN stability and activity R-HSA-8948751
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
Negative regulation of NOTCH4 signaling R-HSA-9604323
G1/S Transition R-HSA-69206
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Synthesis of DNA R-HSA-69239
KEAP1-NFE2L2 pathway R-HSA-9755511
Mitotic G2-G2/M phases R-HSA-453274
PTEN Regulation R-HSA-6807070
Regulation of Apoptosis R-HSA-169911
Hh mutants abrogate ligand secretion R-HSA-5387390
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Metabolism of proteins R-HSA-392499
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
DNA Replication R-HSA-69306
Ub-specific processing proteases R-HSA-5689880
Degradation of GLI2 by the proteasome R-HSA-5610783
Vif-mediated degradation of APOBEC3G R-HSA-180585
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Nuclear events mediated by NFE2L2 R-HSA-9759194
Gene expression (Transcription) R-HSA-74160
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cellular responses to stimuli R-HSA-8953897
Interleukin-1 family signaling R-HSA-446652
Regulation of RUNX2 expression and activity R-HSA-8939902
G2/M Transition R-HSA-69275
Signaling by ROBO receptors R-HSA-376176
Mitotic G1 phase and G1/S transition R-HSA-453279
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Metabolism of amino acids and derivatives R-HSA-71291
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Orc1 removal from chromatin R-HSA-68949
Transcriptional regulation by RUNX1 R-HSA-8878171
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Antigen processing-Cross presentation R-HSA-1236975
TCF dependent signaling in response to WNT R-HSA-201681
M Phase R-HSA-68886
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of GLI1 by the proteasome R-HSA-5610780
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Cellular response to hypoxia R-HSA-1234174
Intracellular signaling by second messengers R-HSA-9006925
Cell Cycle, Mitotic R-HSA-69278
PIP3 activates AKT signaling R-HSA-1257604
Host Interactions of HIV factors R-HSA-162909
FCERI mediated NF-kB activation R-HSA-2871837
Interleukin-1 signaling R-HSA-9020702
Signal Transduction R-HSA-162582
Disorders of transmembrane transporters R-HSA-5619115
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Developmental Biology R-HSA-1266738
Axon guidance R-HSA-422475
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Transcriptional regulation by RUNX3 R-HSA-8878159
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Metabolism of polyamines R-HSA-351202
Assembly of the pre-replicative complex R-HSA-68867
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Orc1 removal from chromatin R-HSA-68949
MAPK family signaling cascades R-HSA-5683057
ER-Phagosome pathway R-HSA-1236974
Gene expression (Transcription) R-HSA-74160
UCH proteinases R-HSA-5689603
Neddylation R-HSA-8951664
Degradation of AXIN R-HSA-4641257
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
Cellular responses to stress R-HSA-2262752
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hedgehog 'on' state R-HSA-5632684
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Asymmetric localization of PCP proteins R-HSA-4608870
Synthesis of DNA R-HSA-69239
Degradation of DVL R-HSA-4641258
Hh mutants abrogate ligand secretion R-HSA-5387390
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Immune System R-HSA-168256
Signaling by NOTCH R-HSA-157118
Mitotic G2-G2/M phases R-HSA-453274
Metabolism R-HSA-1430728
MAPK1/MAPK3 signaling R-HSA-5684996
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Regulation of RUNX2 expression and activity R-HSA-8939902
Cell Cycle R-HSA-1640170
RAF/MAP kinase cascade R-HSA-5673001
Cellular response to hypoxia R-HSA-1234174
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Signaling by NOTCH4 R-HSA-9013694
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signal Transduction R-HSA-162582
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of mitotic cell cycle R-HSA-453276
ABC transporter disorders R-HSA-5619084
Defective CFTR causes cystic fibrosis R-HSA-5678895
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCR signaling R-HSA-202403
Regulation of Apoptosis R-HSA-169911
S Phase R-HSA-69242
Signaling by Interleukins R-HSA-449147
DNA Replication R-HSA-69306
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Metabolism of proteins R-HSA-392499
Cyclin E associated events during G1/S transition R-HSA-69202
Negative regulation of NOTCH4 signaling R-HSA-9604323
Disease R-HSA-1643685
Signaling by Hedgehog R-HSA-5358351
Mitotic Metaphase and Anaphase R-HSA-2555396
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
HIV Infection R-HSA-162906
Degradation of GLI1 by the proteasome R-HSA-5610780
Programmed Cell Death R-HSA-5357801
Metabolism of RNA R-HSA-8953854
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Degradation of beta-catenin by the destruction complex R-HSA-195253
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Transcriptional regulation by RUNX1 R-HSA-8878171
Post-translational protein modification R-HSA-597592
Regulation of RAS by GAPs R-HSA-5658442
Deubiquitination R-HSA-5688426
Adaptive Immune System R-HSA-1280218
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ub-specific processing proteases R-HSA-5689880
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
Signaling by ROBO receptors R-HSA-376176
Cell Cycle, Mitotic R-HSA-69278
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Infectious disease R-HSA-5663205
Generic Transcription Pathway R-HSA-212436
Interleukin-1 family signaling R-HSA-446652
M Phase R-HSA-68886
Hh mutants are degraded by ERAD R-HSA-5362768
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Cellular responses to stimuli R-HSA-8953897
Cell Cycle Checkpoints R-HSA-69620
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI2 by the proteasome R-HSA-5610783
Regulation of RUNX3 expression and activity R-HSA-8941858
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Signaling by WNT R-HSA-195721
PCP/CE pathway R-HSA-4086400
PIP3 activates AKT signaling R-HSA-1257604
Cellular response to chemical stress R-HSA-9711123
Vpu mediated degradation of CD4 R-HSA-180534
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of PTEN stability and activity R-HSA-8948751
Stabilization of p53 R-HSA-69541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
NIK-->noncanonical NF-kB signaling R-HSA-5676590
p53-Independent DNA Damage Response R-HSA-69610
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of amino acids and derivatives R-HSA-71291
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Mitotic Anaphase R-HSA-68882
Downstream TCR signaling R-HSA-202424
Host Interactions of HIV factors R-HSA-162909
Intracellular signaling by second messengers R-HSA-9006925
Hedgehog 'off' state R-HSA-5610787
CLEC7A (Dectin-1) signaling R-HSA-5607764
Antigen processing-Cross presentation R-HSA-1236975
FCERI mediated NF-kB activation R-HSA-2871837
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
KEAP1-NFE2L2 pathway R-HSA-9755511
Cytokine Signaling in Immune system R-HSA-1280215
Hedgehog ligand biogenesis R-HSA-5358346
C-type lectin receptors (CLRs) R-HSA-5621481
Switching of origins to a post-replicative state R-HSA-69052
Apoptosis R-HSA-109581
Transport of small molecules R-HSA-382551
G1/S Transition R-HSA-69206
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Transcriptional regulation by RUNX2 R-HSA-8878166
Interleukin-1 signaling R-HSA-9020702
Innate Immune System R-HSA-168249
DNA Replication Pre-Initiation R-HSA-69002
PTEN Regulation R-HSA-6807070
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
G1/S DNA Damage Checkpoints R-HSA-69615
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Nervous system development R-HSA-9675108
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
M Phase R-HSA-68886
Degradation of GLI1 by the proteasome R-HSA-5610780
Apoptosis R-HSA-109581
PCP/CE pathway R-HSA-4086400
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
DNA Replication Pre-Initiation R-HSA-69002
Degradation of DVL R-HSA-4641258
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
p53-Dependent G1 DNA Damage Response R-HSA-69563
Axon guidance R-HSA-422475
ABC transporter disorders R-HSA-5619084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Generic Transcription Pathway R-HSA-212436
Cell Cycle Checkpoints R-HSA-69620
PTEN Regulation R-HSA-6807070
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
p53-Independent DNA Damage Response R-HSA-69610
Asymmetric localization of PCP proteins R-HSA-4608870
Hh mutants abrogate ligand secretion R-HSA-5387390
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Stabilization of p53 R-HSA-69541
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
ABC-family proteins mediated transport R-HSA-382556
G2/M Transition R-HSA-69275
PIP3 activates AKT signaling R-HSA-1257604
Signaling by Hedgehog R-HSA-5358351
Hedgehog 'on' state R-HSA-5632684
Immune System R-HSA-168256
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Regulation of PTEN stability and activity R-HSA-8948751
RAF/MAP kinase cascade R-HSA-5673001
Mitotic Metaphase and Anaphase R-HSA-2555396
Degradation of AXIN R-HSA-4641257
Metabolism of amino acids and derivatives R-HSA-71291
TCF dependent signaling in response to WNT R-HSA-201681
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
CLEC7A (Dectin-1) signaling R-HSA-5607764
Vpu mediated degradation of CD4 R-HSA-180534
G1/S DNA Damage Checkpoints R-HSA-69615
RNA Polymerase II Transcription R-HSA-73857
Cellular response to chemical stress R-HSA-9711123
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
Signaling by the B Cell Receptor (BCR) R-HSA-983705
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Regulation of mitotic cell cycle R-HSA-453276
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Class I MHC mediated antigen processing & presentation R-HSA-983169
Programmed Cell Death R-HSA-5357801
Separation of Sister Chromatids R-HSA-2467813
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Nuclear events mediated by NFE2L2 R-HSA-9759194
Interleukin-1 signaling R-HSA-9020702
G2/M Checkpoints R-HSA-69481
Metabolism of proteins R-HSA-392499
Orc1 removal from chromatin R-HSA-68949
Defective CFTR causes cystic fibrosis R-HSA-5678895
HIV Infection R-HSA-162906
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Post-translational protein modification R-HSA-597592
UCH proteinases R-HSA-5689603
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of Apoptosis R-HSA-169911
Adaptive Immune System R-HSA-1280218
Disorders of transmembrane transporters R-HSA-5619115
Activation of NF-kappaB in B cells R-HSA-1169091
Signaling by ROBO receptors R-HSA-376176
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Assembly of the pre-replicative complex R-HSA-68867
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Innate Immune System R-HSA-168249
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Synthesis of DNA R-HSA-69239
Switching of origins to a post-replicative state R-HSA-69052
Infectious disease R-HSA-5663205
Transcriptional regulation by RUNX1 R-HSA-8878171
KEAP1-NFE2L2 pathway R-HSA-9755511
Ub-specific processing proteases R-HSA-5689880
Signaling by Interleukins R-HSA-449147
MAPK6/MAPK4 signaling R-HSA-5687128
DNA Replication R-HSA-69306
Hedgehog ligand biogenesis R-HSA-5358346
Cellular responses to stress R-HSA-2262752
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Signaling by NOTCH4 R-HSA-9013694
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Disease R-HSA-1643685
Deubiquitination R-HSA-5688426
Hh mutants are degraded by ERAD R-HSA-5362768
Regulation of RUNX3 expression and activity R-HSA-8941858
MAPK family signaling cascades R-HSA-5683057
Intracellular signaling by second messengers R-HSA-9006925
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Negative regulation of NOTCH4 signaling R-HSA-9604323
Antigen processing-Cross presentation R-HSA-1236975
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic G2-G2/M phases R-HSA-453274
ER-Phagosome pathway R-HSA-1236974
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Signal Transduction R-HSA-162582
Gene expression (Transcription) R-HSA-74160
Host Interactions of HIV factors R-HSA-162909
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Cellular response to hypoxia R-HSA-1234174
Cell Cycle R-HSA-1640170
Hedgehog 'off' state R-HSA-5610787
Cellular responses to stimuli R-HSA-8953897
Developmental Biology R-HSA-1266738
S Phase R-HSA-69242
Degradation of beta-catenin by the destruction complex R-HSA-195253
Degradation of GLI2 by the proteasome R-HSA-5610783
Cytokine Signaling in Immune system R-HSA-1280215
Vif-mediated degradation of APOBEC3G R-HSA-180585
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism of RNA R-HSA-8953854
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Regulation of RAS by GAPs R-HSA-5658442
Transcriptional regulation by RUNX2 R-HSA-8878166
G1/S Transition R-HSA-69206
Metabolism R-HSA-1430728
Transport of small molecules R-HSA-382551
Interleukin-1 family signaling R-HSA-446652
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Mitotic Anaphase R-HSA-68882
Signaling by WNT R-HSA-195721
Transcriptional regulation by RUNX1 R-HSA-8878171
G2/M Checkpoints R-HSA-69481
Downstream TCR signaling R-HSA-202424
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
MAPK6/MAPK4 signaling R-HSA-5687128
Beta-catenin independent WNT signaling R-HSA-3858494
PTEN Regulation R-HSA-6807070
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Hh mutants are degraded by ERAD R-HSA-5362768
Orc1 removal from chromatin R-HSA-68949
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Generic Transcription Pathway R-HSA-212436
S Phase R-HSA-69242
Ub-specific processing proteases R-HSA-5689880
Negative regulation of NOTCH4 signaling R-HSA-9604323
Stabilization of p53 R-HSA-69541
Regulation of Apoptosis R-HSA-169911
Cell Cycle Checkpoints R-HSA-69620
Regulation of mitotic cell cycle R-HSA-453276
Metabolism of proteins R-HSA-392499
Nervous system development R-HSA-9675108
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
FCERI mediated NF-kB activation R-HSA-2871837
Nuclear events mediated by NFE2L2 R-HSA-9759194
PCP/CE pathway R-HSA-4086400
DNA Replication Pre-Initiation R-HSA-69002
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
UCH proteinases R-HSA-5689603
Cellular responses to stimuli R-HSA-8953897
Neddylation R-HSA-8951664
M Phase R-HSA-68886
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
KEAP1-NFE2L2 pathway R-HSA-9755511
Innate Immune System R-HSA-168249
Infectious disease R-HSA-5663205
Cell Cycle R-HSA-1640170
RNA Polymerase II Transcription R-HSA-73857
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Vpu mediated degradation of CD4 R-HSA-180534
Antigen processing-Cross presentation R-HSA-1236975
Vif-mediated degradation of APOBEC3G R-HSA-180585
Transcriptional regulation by RUNX2 R-HSA-8878166
Degradation of AXIN R-HSA-4641257
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of RAS by GAPs R-HSA-5658442
Immune System R-HSA-168256
DNA Replication R-HSA-69306
Axon guidance R-HSA-422475
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Signal Transduction R-HSA-162582
Mitotic G1 phase and G1/S transition R-HSA-453279
Degradation of DVL R-HSA-4641258
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
ER-Phagosome pathway R-HSA-1236974
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Intracellular signaling by second messengers R-HSA-9006925
HIV Infection R-HSA-162906
Cell Cycle, Mitotic R-HSA-69278
RAF/MAP kinase cascade R-HSA-5673001
Disease R-HSA-1643685
Signaling by Interleukins R-HSA-449147
Metabolism of RNA R-HSA-8953854
G1/S Transition R-HSA-69206
G2/M Transition R-HSA-69275
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Defective CFTR causes cystic fibrosis R-HSA-5678895
Metabolism of polyamines R-HSA-351202
Hedgehog 'off' state R-HSA-5610787
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
TCF dependent signaling in response to WNT R-HSA-201681
C-type lectin receptors (CLRs) R-HSA-5621481
ABC transporter disorders R-HSA-5619084
Disorders of transmembrane transporters R-HSA-5619115
Signaling by NOTCH R-HSA-157118
Cyclin E associated events during G1/S transition R-HSA-69202
G1/S DNA Damage Checkpoints R-HSA-69615
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Separation of Sister Chromatids R-HSA-2467813
Metabolism R-HSA-1430728
p53-Dependent G1 DNA Damage Response R-HSA-69563
Regulation of RUNX3 expression and activity R-HSA-8941858
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Signaling by ROBO receptors R-HSA-376176
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Interleukin-1 signaling R-HSA-9020702
Mitotic Anaphase R-HSA-68882
ABC-family proteins mediated transport R-HSA-382556
Programmed Cell Death R-HSA-5357801
MAPK family signaling cascades R-HSA-5683057
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Regulation of PTEN stability and activity R-HSA-8948751
Cellular response to chemical stress R-HSA-9711123
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by NOTCH4 R-HSA-9013694
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
p53-Independent DNA Damage Response R-HSA-69610
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stress R-HSA-2262752
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transport of small molecules R-HSA-382551
MAPK1/MAPK3 signaling R-HSA-5684996
Signaling by Hedgehog R-HSA-5358351
Metabolism of amino acids and derivatives R-HSA-71291
Transcriptional regulation by RUNX3 R-HSA-8878159
Mitotic G2-G2/M phases R-HSA-453274
Asymmetric localization of PCP proteins R-HSA-4608870
Switching of origins to a post-replicative state R-HSA-69052
Cellular response to hypoxia R-HSA-1234174
Developmental Biology R-HSA-1266738
Regulation of RUNX2 expression and activity R-HSA-8939902
Adaptive Immune System R-HSA-1280218
Post-translational protein modification R-HSA-597592
Apoptosis R-HSA-109581
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Hedgehog ligand biogenesis R-HSA-5358346
Gene expression (Transcription) R-HSA-74160
TCR signaling R-HSA-202403
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Hh mutants abrogate ligand secretion R-HSA-5387390
Activation of NF-kappaB in B cells R-HSA-1169091
Class I MHC mediated antigen processing & presentation R-HSA-983169
Interleukin-1 family signaling R-HSA-446652
Degradation of GLI2 by the proteasome R-HSA-5610783
Deubiquitination R-HSA-5688426
PIP3 activates AKT signaling R-HSA-1257604
Innate Immune System R-HSA-168249
HIV Infection R-HSA-162906
Vif-mediated degradation of APOBEC3G R-HSA-180585
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism of polyamines R-HSA-351202
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Class I MHC mediated antigen processing & presentation R-HSA-983169
ABC-family proteins mediated transport R-HSA-382556
Metabolism R-HSA-1430728
PCP/CE pathway R-HSA-4086400
FCERI mediated NF-kB activation R-HSA-2871837
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Gene expression (Transcription) R-HSA-74160
NIK-->noncanonical NF-kB signaling R-HSA-5676590
MAPK6/MAPK4 signaling R-HSA-5687128
G2/M Transition R-HSA-69275
Transport of small molecules R-HSA-382551
Cell Cycle Checkpoints R-HSA-69620
Stabilization of p53 R-HSA-69541
Orc1 removal from chromatin R-HSA-68949
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Ub-specific processing proteases R-HSA-5689880
Degradation of AXIN R-HSA-4641257
Developmental Biology R-HSA-1266738
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Mitotic G2-G2/M phases R-HSA-453274
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Hedgehog 'on' state R-HSA-5632684
Degradation of DVL R-HSA-4641258
Cell Cycle R-HSA-1640170
Cellular responses to stimuli R-HSA-8953897
Post-translational protein modification R-HSA-597592
Vpu mediated degradation of CD4 R-HSA-180534
MAPK1/MAPK3 signaling R-HSA-5684996
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
UCH proteinases R-HSA-5689603
Metabolism of amino acids and derivatives R-HSA-71291
Disease R-HSA-1643685
Interleukin-1 signaling R-HSA-9020702
Signaling by Interleukins R-HSA-449147
Negative regulation of NOTCH4 signaling R-HSA-9604323
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
KEAP1-NFE2L2 pathway R-HSA-9755511
Neddylation R-HSA-8951664
Regulation of RUNX2 expression and activity R-HSA-8939902
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Metabolism of proteins R-HSA-392499
Infectious disease R-HSA-5663205
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Disorders of transmembrane transporters R-HSA-5619115
Synthesis of DNA R-HSA-69239
Regulation of PTEN stability and activity R-HSA-8948751
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Host Interactions of HIV factors R-HSA-162909
Hh mutants are degraded by ERAD R-HSA-5362768
ABC transporter disorders R-HSA-5619084
Signaling by ROBO receptors R-HSA-376176
Axon guidance R-HSA-422475
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of mitotic cell cycle R-HSA-453276
TCR signaling R-HSA-202403
Mitotic Metaphase and Anaphase R-HSA-2555396
p53-Independent DNA Damage Response R-HSA-69610
Cellular responses to stress R-HSA-2262752
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Deubiquitination R-HSA-5688426
Separation of Sister Chromatids R-HSA-2467813
M Phase R-HSA-68886
Hedgehog 'off' state R-HSA-5610787
PTEN Regulation R-HSA-6807070
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Signaling by Hedgehog R-HSA-5358351
Transcriptional regulation by RUNX3 R-HSA-8878159
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
RAF/MAP kinase cascade R-HSA-5673001
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Hh mutants abrogate ligand secretion R-HSA-5387390
Regulation of expression of SLITs and ROBOs R-HSA-9010553
C-type lectin receptors (CLRs) R-HSA-5621481
Apoptosis R-HSA-109581
Adaptive Immune System R-HSA-1280218
DNA Replication R-HSA-69306
G1/S DNA Damage Checkpoints R-HSA-69615
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Cellular response to hypoxia R-HSA-1234174
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
Downstream TCR signaling R-HSA-202424
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Generic Transcription Pathway R-HSA-212436
RNA Polymerase II Transcription R-HSA-73857
Intracellular signaling by second messengers R-HSA-9006925
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
PIP3 activates AKT signaling R-HSA-1257604
Transcriptional regulation by RUNX2 R-HSA-8878166
Antigen processing-Cross presentation R-HSA-1236975
Cellular response to chemical stress R-HSA-9711123
Nervous system development R-HSA-9675108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Degradation of beta-catenin by the destruction complex R-HSA-195253
Asymmetric localization of PCP proteins R-HSA-4608870
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Activation of NF-kappaB in B cells R-HSA-1169091
Degradation of GLI1 by the proteasome R-HSA-5610780
Signaling by WNT R-HSA-195721
Regulation of RUNX3 expression and activity R-HSA-8941858
Immune System R-HSA-168256
G1/S Transition R-HSA-69206
p53-Dependent G1 DNA Damage Response R-HSA-69563
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
MAPK family signaling cascades R-HSA-5683057
DNA Replication Pre-Initiation R-HSA-69002
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ER-Phagosome pathway R-HSA-1236974
Regulation of RAS by GAPs R-HSA-5658442
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Interleukin-1 family signaling R-HSA-446652
Signaling by NOTCH R-HSA-157118
Signaling by NOTCH4 R-HSA-9013694
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Switching of origins to a post-replicative state R-HSA-69052
Assembly of the pre-replicative complex R-HSA-68867
G2/M Checkpoints R-HSA-69481
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Defective CFTR causes cystic fibrosis R-HSA-5678895
Transcriptional regulation by RUNX1 R-HSA-8878171
Hedgehog ligand biogenesis R-HSA-5358346
Cell Cycle, Mitotic R-HSA-69278
Regulation of Apoptosis R-HSA-169911
Beta-catenin independent WNT signaling R-HSA-3858494
Nuclear events mediated by NFE2L2 R-HSA-9759194
Programmed Cell Death R-HSA-5357801
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic G1 phase and G1/S transition R-HSA-453279
Signal Transduction R-HSA-162582
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Degradation of GLI2 by the proteasome R-HSA-5610783
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
Cellular responses to stimuli R-HSA-8953897
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Interleukin-1 signaling R-HSA-9020702
Hedgehog 'off' state R-HSA-5610787
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Infectious disease R-HSA-5663205
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Degradation of beta-catenin by the destruction complex R-HSA-195253
Post-translational protein modification R-HSA-597592
Cellular response to chemical stress R-HSA-9711123
M Phase R-HSA-68886
p53-Independent DNA Damage Response R-HSA-69610
G2/M Checkpoints R-HSA-69481
Regulation of Apoptosis R-HSA-169911
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Transcriptional regulation by RUNX2 R-HSA-8878166
Signaling by ROBO receptors R-HSA-376176
Cytokine Signaling in Immune system R-HSA-1280215
G2/M Transition R-HSA-69275
FCERI mediated NF-kB activation R-HSA-2871837
Asymmetric localization of PCP proteins R-HSA-4608870
UCH proteinases R-HSA-5689603
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Nuclear events mediated by NFE2L2 R-HSA-9759194
Hh mutants abrogate ligand secretion R-HSA-5387390
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Activation of NF-kappaB in B cells R-HSA-1169091
C-type lectin receptors (CLRs) R-HSA-5621481
Signaling by NOTCH R-HSA-157118
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Innate Immune System R-HSA-168249
Defective CFTR causes cystic fibrosis R-HSA-5678895
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Hedgehog ligand biogenesis R-HSA-5358346
Adaptive Immune System R-HSA-1280218
Signaling by the B Cell Receptor (BCR) R-HSA-983705
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Beta-catenin independent WNT signaling R-HSA-3858494
Metabolism R-HSA-1430728
PTEN Regulation R-HSA-6807070
MAPK family signaling cascades R-HSA-5683057
Antigen processing-Cross presentation R-HSA-1236975
Metabolism of RNA R-HSA-8953854
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Negative regulation of NOTCH4 signaling R-HSA-9604323
Hedgehog 'on' state R-HSA-5632684
Transcriptional regulation by RUNX3 R-HSA-8878159
Axon guidance R-HSA-422475
Assembly of the pre-replicative complex R-HSA-68867
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Apoptosis R-HSA-109581
Signaling by WNT R-HSA-195721
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Regulation of PTEN stability and activity R-HSA-8948751
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
G1/S DNA Damage Checkpoints R-HSA-69615
TCF dependent signaling in response to WNT R-HSA-201681
Transcriptional regulation by RUNX1 R-HSA-8878171
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Class I MHC mediated antigen processing & presentation R-HSA-983169
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
KEAP1-NFE2L2 pathway R-HSA-9755511
Cellular responses to stress R-HSA-2262752
TCR signaling R-HSA-202403
DNA Replication R-HSA-69306
Cellular response to hypoxia R-HSA-1234174
Metabolism of proteins R-HSA-392499
HIV Infection R-HSA-162906
Signaling by Hedgehog R-HSA-5358351
Cell Cycle Checkpoints R-HSA-69620
Vif-mediated degradation of APOBEC3G R-HSA-180585
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Switching of origins to a post-replicative state R-HSA-69052
S Phase R-HSA-69242
Programmed Cell Death R-HSA-5357801
Mitotic G2-G2/M phases R-HSA-453274
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Interleukin-1 family signaling R-HSA-446652
Degradation of AXIN R-HSA-4641257
RNA Polymerase II Transcription R-HSA-73857
Deubiquitination R-HSA-5688426
RAF/MAP kinase cascade R-HSA-5673001
Transport of small molecules R-HSA-382551
Signaling by Interleukins R-HSA-449147
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Metabolism of amino acids and derivatives R-HSA-71291
ABC transporter disorders R-HSA-5619084
PCP/CE pathway R-HSA-4086400
Degradation of GLI1 by the proteasome R-HSA-5610780
Stabilization of p53 R-HSA-69541
PIP3 activates AKT signaling R-HSA-1257604
Regulation of RUNX2 expression and activity R-HSA-8939902
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Synthesis of DNA R-HSA-69239
Intracellular signaling by second messengers R-HSA-9006925
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Developmental Biology R-HSA-1266738
Cyclin E associated events during G1/S transition R-HSA-69202
Regulation of RAS by GAPs R-HSA-5658442
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Ub-specific processing proteases R-HSA-5689880
Signal Transduction R-HSA-162582
ABC-family proteins mediated transport R-HSA-382556
DNA Replication Pre-Initiation R-HSA-69002
Disease R-HSA-1643685
Separation of Sister Chromatids R-HSA-2467813
Disorders of transmembrane transporters R-HSA-5619115
Mitotic G1 phase and G1/S transition R-HSA-453279
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants are degraded by ERAD R-HSA-5362768
Host Interactions of HIV factors R-HSA-162909
Regulation of mitotic cell cycle R-HSA-453276
MAPK1/MAPK3 signaling R-HSA-5684996
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Neddylation R-HSA-8951664
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
MAPK6/MAPK4 signaling R-HSA-5687128
Regulation of RUNX3 expression and activity R-HSA-8941858
Mitotic Anaphase R-HSA-68882
G1/S Transition R-HSA-69206
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Mitotic Metaphase and Anaphase R-HSA-2555396
Nervous system development R-HSA-9675108
Cell Cycle, Mitotic R-HSA-69278
ER-Phagosome pathway R-HSA-1236974
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Orc1 removal from chromatin R-HSA-68949
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Immune System R-HSA-168256
Vpu mediated degradation of CD4 R-HSA-180534
Metabolism of polyamines R-HSA-351202
PTEN Regulation R-HSA-6807070
Metabolism R-HSA-1430728
Infectious disease R-HSA-5663205
C-type lectin receptors (CLRs) R-HSA-5621481
Disease R-HSA-1643685
Mitotic Anaphase R-HSA-68882
Signaling by ROBO receptors R-HSA-376176
Immune System R-HSA-168256
Assembly of the pre-replicative complex R-HSA-68867
Vif-mediated degradation of APOBEC3G R-HSA-180585
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Cellular response to hypoxia R-HSA-1234174
Ub-specific processing proteases R-HSA-5689880
Programmed Cell Death R-HSA-5357801
Transcriptional regulation by RUNX3 R-HSA-8878159
Degradation of AXIN R-HSA-4641257
Apoptosis R-HSA-109581
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Degradation of beta-catenin by the destruction complex R-HSA-195253
Signaling by NOTCH4 R-HSA-9013694
Regulation of Apoptosis R-HSA-169911
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Axon guidance R-HSA-422475
Metabolism of amino acids and derivatives R-HSA-71291
FCERI mediated NF-kB activation R-HSA-2871837
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
Interleukin-1 signaling R-HSA-9020702
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Transcriptional regulation by RUNX2 R-HSA-8878166
Deubiquitination R-HSA-5688426
Cell Cycle Checkpoints R-HSA-69620
Interleukin-1 family signaling R-HSA-446652
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
ABC transporter disorders R-HSA-5619084
Signal Transduction R-HSA-162582
Cellular response to chemical stress R-HSA-9711123
Switching of origins to a post-replicative state R-HSA-69052
TCF dependent signaling in response to WNT R-HSA-201681
Cytokine Signaling in Immune system R-HSA-1280215
S Phase R-HSA-69242
Degradation of GLI2 by the proteasome R-HSA-5610783
G2/M Transition R-HSA-69275
Metabolism of RNA R-HSA-8953854
Synthesis of DNA R-HSA-69239
Hedgehog 'on' state R-HSA-5632684
DNA Replication R-HSA-69306
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
G1/S DNA Damage Checkpoints R-HSA-69615
Signaling by Interleukins R-HSA-449147
Cellular responses to stress R-HSA-2262752
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
ABC-family proteins mediated transport R-HSA-382556
Metabolism of proteins R-HSA-392499
MAPK6/MAPK4 signaling R-HSA-5687128
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Negative regulation of NOTCH4 signaling R-HSA-9604323
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
CLEC7A (Dectin-1) signaling R-HSA-5607764
Orc1 removal from chromatin R-HSA-68949
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Transcriptional regulation by RUNX1 R-HSA-8878171
Antigen processing-Cross presentation R-HSA-1236975
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Beta-catenin independent WNT signaling R-HSA-3858494
RAF/MAP kinase cascade R-HSA-5673001
Nervous system development R-HSA-9675108
Transport of small molecules R-HSA-382551
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Disorders of transmembrane transporters R-HSA-5619115
Signaling by Hedgehog R-HSA-5358351
MAPK family signaling cascades R-HSA-5683057
Hedgehog ligand biogenesis R-HSA-5358346
Stabilization of p53 R-HSA-69541
HIV Infection R-HSA-162906
Developmental Biology R-HSA-1266738
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
G1/S Transition R-HSA-69206
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of RAS by GAPs R-HSA-5658442
Cell Cycle R-HSA-1640170
Mitotic G2-G2/M phases R-HSA-453274
Hedgehog 'off' state R-HSA-5610787
ER-Phagosome pathway R-HSA-1236974
Separation of Sister Chromatids R-HSA-2467813
Mitotic G1 phase and G1/S transition R-HSA-453279
TCR signaling R-HSA-202403
G2/M Checkpoints R-HSA-69481
M Phase R-HSA-68886
Neddylation R-HSA-8951664
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Nuclear events mediated by NFE2L2 R-HSA-9759194
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Intracellular signaling by second messengers R-HSA-9006925
PIP3 activates AKT signaling R-HSA-1257604
Degradation of GLI1 by the proteasome R-HSA-5610780
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Vpu mediated degradation of CD4 R-HSA-180534
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Hh mutants are degraded by ERAD R-HSA-5362768
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Hh mutants abrogate ligand secretion R-HSA-5387390
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism of polyamines R-HSA-351202
Defective CFTR causes cystic fibrosis R-HSA-5678895
PCP/CE pathway R-HSA-4086400
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
MAPK1/MAPK3 signaling R-HSA-5684996
Cell Cycle, Mitotic R-HSA-69278
Adaptive Immune System R-HSA-1280218
Activation of NF-kappaB in B cells R-HSA-1169091
DNA Replication Pre-Initiation R-HSA-69002
p53-Dependent G1 DNA Damage Response R-HSA-69563
UCH proteinases R-HSA-5689603
p53-Independent DNA Damage Response R-HSA-69610
Generic Transcription Pathway R-HSA-212436
Class I MHC mediated antigen processing & presentation R-HSA-983169
Cyclin E associated events during G1/S transition R-HSA-69202
Mitotic Metaphase and Anaphase R-HSA-2555396
Downstream TCR signaling R-HSA-202424
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Innate Immune System R-HSA-168249
Regulation of mitotic cell cycle R-HSA-453276
Signaling by WNT R-HSA-195721
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Gene expression (Transcription) R-HSA-74160
Post-translational protein modification R-HSA-597592
Host Interactions of HIV factors R-HSA-162909
Cellular responses to stimuli R-HSA-8953897
Regulation of PTEN stability and activity R-HSA-8948751
Signaling by NOTCH R-HSA-157118
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
Asymmetric localization of PCP proteins R-HSA-4608870
Programmed Cell Death R-HSA-5357801
Metabolism of proteins R-HSA-392499
Disease R-HSA-1643685
Regulation of RUNX3 expression and activity R-HSA-8941858
RNA Polymerase II Transcription R-HSA-73857
Hedgehog ligand biogenesis R-HSA-5358346
ER-Phagosome pathway R-HSA-1236974
Signal Transduction R-HSA-162582
Signaling by NOTCH4 R-HSA-9013694
Stabilization of p53 R-HSA-69541
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of polyamines R-HSA-351202
Cyclin E associated events during G1/S transition R-HSA-69202
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
Assembly of the pre-replicative complex R-HSA-68867
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Degradation of GLI2 by the proteasome R-HSA-5610783
C-type lectin receptors (CLRs) R-HSA-5621481
Intracellular signaling by second messengers R-HSA-9006925
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
MAPK1/MAPK3 signaling R-HSA-5684996
Transcriptional regulation by RUNX3 R-HSA-8878159
Signaling by Interleukins R-HSA-449147
MAPK family signaling cascades R-HSA-5683057
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
RAF/MAP kinase cascade R-HSA-5673001
Transcriptional regulation by RUNX1 R-HSA-8878171
p53-Independent DNA Damage Response R-HSA-69610
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
Mitotic Metaphase and Anaphase R-HSA-2555396
FCERI mediated NF-kB activation R-HSA-2871837
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Separation of Sister Chromatids R-HSA-2467813
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Ub-specific processing proteases R-HSA-5689880
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Metabolism R-HSA-1430728
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Activation of NF-kappaB in B cells R-HSA-1169091
Defective CFTR causes cystic fibrosis R-HSA-5678895
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
Synthesis of DNA R-HSA-69239
Metabolism of amino acids and derivatives R-HSA-71291
PIP3 activates AKT signaling R-HSA-1257604
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Signaling by Hedgehog R-HSA-5358351
Gene expression (Transcription) R-HSA-74160
Regulation of mitotic cell cycle R-HSA-453276
Nuclear events mediated by NFE2L2 R-HSA-9759194
Asymmetric localization of PCP proteins R-HSA-4608870
Hedgehog 'off' state R-HSA-5610787
Metabolism of RNA R-HSA-8953854
KEAP1-NFE2L2 pathway R-HSA-9755511
Negative regulation of NOTCH4 signaling R-HSA-9604323
Signaling by WNT R-HSA-195721
Cellular response to chemical stress R-HSA-9711123
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
Innate Immune System R-HSA-168249
Transport of small molecules R-HSA-382551
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
PCP/CE pathway R-HSA-4086400
Regulation of expression of SLITs and ROBOs R-HSA-9010553
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Cell Cycle Checkpoints R-HSA-69620
Degradation of AXIN R-HSA-4641257
PTEN Regulation R-HSA-6807070
Neddylation R-HSA-8951664
Downstream TCR signaling R-HSA-202424
Switching of origins to a post-replicative state R-HSA-69052
DNA Replication Pre-Initiation R-HSA-69002
Beta-catenin independent WNT signaling R-HSA-3858494
MAPK6/MAPK4 signaling R-HSA-5687128
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
ABC transporter disorders R-HSA-5619084
NIK-->noncanonical NF-kB signaling R-HSA-5676590
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Disorders of transmembrane transporters R-HSA-5619115
Immune System R-HSA-168256
Apoptosis R-HSA-109581
Regulation of Apoptosis R-HSA-169911
G1/S DNA Damage Checkpoints R-HSA-69615
Hh mutants are degraded by ERAD R-HSA-5362768
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
Adaptive Immune System R-HSA-1280218
Degradation of beta-catenin by the destruction complex R-HSA-195253
Transcriptional regulation by RUNX2 R-HSA-8878166
Orc1 removal from chromatin R-HSA-68949
Infectious disease R-HSA-5663205
ABC-family proteins mediated transport R-HSA-382556
DNA Replication R-HSA-69306
Post-translational protein modification R-HSA-597592
Interleukin-1 signaling R-HSA-9020702
Degradation of GLI1 by the proteasome R-HSA-5610780
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
Mitotic G1 phase and G1/S transition R-HSA-453279
Mitotic G2-G2/M phases R-HSA-453274
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
Cell Cycle R-HSA-1640170
Generic Transcription Pathway R-HSA-212436
Vif-mediated degradation of APOBEC3G R-HSA-180585
TCF dependent signaling in response to WNT R-HSA-201681
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Nervous system development R-HSA-9675108
Interleukin-1 family signaling R-HSA-446652
G2/M Checkpoints R-HSA-69481
Cellular response to hypoxia R-HSA-1234174
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
p53-Dependent G1 DNA Damage Response R-HSA-69563
Hh mutants abrogate ligand secretion R-HSA-5387390
CLEC7A (Dectin-1) signaling R-HSA-5607764
G1/S Transition R-HSA-69206
Regulation of RAS by GAPs R-HSA-5658442
Class I MHC mediated antigen processing & presentation R-HSA-983169
UCH proteinases R-HSA-5689603
TCR signaling R-HSA-202403
Cell Cycle, Mitotic R-HSA-69278
Regulation of RUNX2 expression and activity R-HSA-8939902
Degradation of DVL R-HSA-4641258
Mitotic Anaphase R-HSA-68882
Axon guidance R-HSA-422475
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Signaling by ROBO receptors R-HSA-376176
Cellular responses to stress R-HSA-2262752
Developmental Biology R-HSA-1266738
Antigen processing-Cross presentation R-HSA-1236975
S Phase R-HSA-69242
Vpu mediated degradation of CD4 R-HSA-180534
Hedgehog 'on' state R-HSA-5632684
HIV Infection R-HSA-162906
Deubiquitination R-HSA-5688426
Host Interactions of HIV factors R-HSA-162909
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
G2/M Transition R-HSA-69275
M Phase R-HSA-68886
Cellular responses to stimuli R-HSA-8953897
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
Regulation of PTEN stability and activity R-HSA-8948751
Class I MHC mediated antigen processing & presentation R-HSA-983169
DNA Replication R-HSA-69306
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761
TCF dependent signaling in response to WNT R-HSA-201681
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815
S Phase R-HSA-69242
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184
Signaling by NOTCH4 R-HSA-9013694
Downstream TCR signaling R-HSA-202424
Cyclin E associated events during G1/S transition R-HSA-69202
Intracellular signaling by second messengers R-HSA-9006925
Defective CFTR causes cystic fibrosis R-HSA-5678895
ABC-family proteins mediated transport R-HSA-382556
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733
p53-Dependent G1 DNA Damage Response R-HSA-69563
Synthesis of DNA R-HSA-69239
Cellular responses to stimuli R-HSA-8953897
Transcriptional regulation by RUNX3 R-HSA-8878159
Infectious disease R-HSA-5663205
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178
Vpu mediated degradation of CD4 R-HSA-180534
Degradation of GLI1 by the proteasome R-HSA-5610780
Generic Transcription Pathway R-HSA-212436
DNA Replication Pre-Initiation R-HSA-69002
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601
ER-Phagosome pathway R-HSA-1236974
Immune System R-HSA-168256
Hedgehog 'on' state R-HSA-5632684
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785
Cellular response to chemical stress R-HSA-9711123
NIK-->noncanonical NF-kB signaling R-HSA-5676590
Asymmetric localization of PCP proteins R-HSA-4608870
Cytokine Signaling in Immune system R-HSA-1280215
Metabolism of RNA R-HSA-8953854
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408
Assembly of the pre-replicative complex R-HSA-68867
Mitotic Metaphase and Anaphase R-HSA-2555396
Hh mutants abrogate ligand secretion R-HSA-5387390
HIV Infection R-HSA-162906
Signaling by ROBO receptors R-HSA-376176
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168
Adaptive Immune System R-HSA-1280218
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176
M Phase R-HSA-68886
Transport of small molecules R-HSA-382551
TNFR2 non-canonical NF-kB pathway R-HSA-5668541
Neddylation R-HSA-8951664
Activation of NF-kappaB in B cells R-HSA-1169091
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580
MAPK family signaling cascades R-HSA-5683057
Regulation of mitotic cell cycle R-HSA-453276
Mitotic G1 phase and G1/S transition R-HSA-453279
Deubiquitination R-HSA-5688426
Mitotic Anaphase R-HSA-68882
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154
Programmed Cell Death R-HSA-5357801
Hedgehog 'off' state R-HSA-5610787
Interleukin-1 family signaling R-HSA-446652
Developmental Biology R-HSA-1266738
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814
UCH proteinases R-HSA-5689603
Stabilization of p53 R-HSA-69541
Degradation of beta-catenin by the destruction complex R-HSA-195253
Metabolism of proteins R-HSA-392499
Apoptosis R-HSA-109581
Regulation of ornithine decarboxylase (ODC) R-HSA-350562
RNA Polymerase II Transcription R-HSA-73857
Nervous system development R-HSA-9675108
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419
Hh mutants are degraded by ERAD R-HSA-5362768
Axon guidance R-HSA-422475
Disorders of transmembrane transporters R-HSA-5619115
Fc epsilon receptor (FCERI) signaling R-HSA-2454202
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113
Cellular responses to stress R-HSA-2262752
Disease R-HSA-1643685
Signaling by WNT R-HSA-195721
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978
TCR signaling R-HSA-202403
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236
Regulation of RAS by GAPs R-HSA-5658442
Regulation of expression of SLITs and ROBOs R-HSA-9010553
Metabolism of polyamines R-HSA-351202
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372
Negative regulation of NOTCH4 signaling R-HSA-9604323
Nuclear events mediated by NFE2L2 R-HSA-9759194
Cellular response to hypoxia R-HSA-1234174
G2/M Checkpoints R-HSA-69481
Ub-specific processing proteases R-HSA-5689880
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531
Signaling by Hedgehog R-HSA-5358351
PCP/CE pathway R-HSA-4086400
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409
Signaling by the B Cell Receptor (BCR) R-HSA-983705
Degradation of AXIN R-HSA-4641257
Mitotic G2-G2/M phases R-HSA-453274
Regulation of Apoptosis R-HSA-169911
p53-Independent DNA Damage Response R-HSA-69610
PIP3 activates AKT signaling R-HSA-1257604
Hedgehog ligand biogenesis R-HSA-5358346
Transcriptional regulation by RUNX2 R-HSA-8878166
Regulation of RUNX3 expression and activity R-HSA-8941858
Degradation of GLI2 by the proteasome R-HSA-5610783
Metabolism R-HSA-1430728
G1/S Transition R-HSA-69206
CLEC7A (Dectin-1) signaling R-HSA-5607764
APC/C-mediated degradation of cell cycle proteins R-HSA-174143
Signaling by Interleukins R-HSA-449147
Metabolism of amino acids and derivatives R-HSA-71291
Cell Cycle R-HSA-1640170
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084
PTEN Regulation R-HSA-6807070
G2/M Transition R-HSA-69275
C-type lectin receptors (CLRs) R-HSA-5621481
MAPK1/MAPK3 signaling R-HSA-5684996
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114
Separation of Sister Chromatids R-HSA-2467813
Vif-mediated degradation of APOBEC3G R-HSA-180585
Gene expression (Transcription) R-HSA-74160
p53-Independent G1/S DNA damage checkpoint R-HSA-69613
FCERI mediated NF-kB activation R-HSA-2871837
MAPK6/MAPK4 signaling R-HSA-5687128
G1/S DNA Damage Checkpoints R-HSA-69615
Interleukin-1 signaling R-HSA-9020702
Antigen processing-Cross presentation R-HSA-1236975
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577
Cell Cycle, Mitotic R-HSA-69278
Orc1 removal from chromatin R-HSA-68949
Host Interactions of HIV factors R-HSA-162909
Regulation of RUNX2 expression and activity R-HSA-8939902
Post-translational protein modification R-HSA-597592
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017
Degradation of DVL R-HSA-4641258
Switching of origins to a post-replicative state R-HSA-69052
ABC transporter disorders R-HSA-5619084
Signaling by NOTCH R-HSA-157118
Beta-catenin independent WNT signaling R-HSA-3858494
Transcriptional regulation by RUNX1 R-HSA-8878171
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425
Innate Immune System R-HSA-168249
Cell Cycle Checkpoints R-HSA-69620
RAF/MAP kinase cascade R-HSA-5673001
KEAP1-NFE2L2 pathway R-HSA-9755511
Regulation of PTEN stability and activity R-HSA-8948751
Signal Transduction R-HSA-162582

Expression Atlas ENSG00000087191
NCBI gene (formerly Entrezgene) 5705
GeneCards 9552
HGNC Symbol HGNC:9552
MIM gene 601681
UniProtKB Gene Name P62195
WikiGene 5705
Gene: FDPS
Ensembl ID : ENSG00000160752
Description: farnesyl diphosphate synthase
Gene Synonyms:
6 APIs:
208 Possible Orthologues:

Cholesterol biosynthesis R-HSA-191273
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Cholesterol biosynthesis R-HSA-191273
Metabolism of lipids R-HSA-556833
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism R-HSA-1430728
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Metabolism of steroids R-HSA-8957322
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Cholesterol biosynthesis R-HSA-191273
Metabolism of lipids R-HSA-556833
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of steroids R-HSA-8957322
Cholesterol biosynthesis R-HSA-191273
Metabolism of lipids R-HSA-556833
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism R-HSA-1430728
Cholesterol biosynthesis R-HSA-191273
Metabolism of steroids R-HSA-8957322
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of lipids R-HSA-556833
Metabolism R-HSA-1430728
Cholesterol biosynthesis R-HSA-191273
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Metabolism of steroids R-HSA-8957322
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Metabolism R-HSA-1430728
Metabolism of lipids R-HSA-556833
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Cholesterol biosynthesis R-HSA-191273
Metabolism of steroids R-HSA-8957322
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of lipids R-HSA-556833
Cholesterol biosynthesis R-HSA-191273
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Activation of gene expression by SREBF (SREBP) R-HSA-2426168
Cholesterol biosynthesis R-HSA-191273
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829
Metabolism of lipids R-HSA-556833
Metabolism of steroids R-HSA-8957322
Metabolism R-HSA-1430728

Expression Atlas ENSG00000160752
NCBI gene (formerly Entrezgene) 2224
GeneCards 3631
HGNC Symbol HGNC:3631
MIM gene 134629
MIM morbid 616631
UniProtKB Gene Name P14324
WikiGene 2224
Gene: CASP8
Ensembl ID : ENSG00000064012
Description: caspase 8
Gene Synonyms: CASP-8,FLICE,MACH,MCH5
1 APIs:
132 Possible Orthologues:

CLEC7A/inflammasome pathway R-HSA-5660668
Diseases of programmed cell death R-HSA-9645723
NOD1/2 Signaling Pathway R-HSA-168638
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulation of necroptotic cell death R-HSA-5675482
TRAIL signaling R-HSA-75158
Programmed Cell Death R-HSA-5357801
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signal Transduction R-HSA-162582
MyD88 cascade initiated on plasma membrane R-HSA-975871
Death Receptor Signaling R-HSA-73887
TRIF-mediated programmed cell death R-HSA-2562578
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TNF signaling R-HSA-75893
FasL/ CD95L signaling R-HSA-75157
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Regulated Necrosis R-HSA-5218859
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signaling by Interleukins R-HSA-449147
Toll-like Receptor Cascades R-HSA-168898
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of TNFR1 signaling R-HSA-5357905
CASP8 activity is inhibited R-HSA-5218900
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TNFR1-induced proapoptotic signaling R-HSA-5357786
Dimerization of procaspase-8 R-HSA-69416
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
MyD88 dependent cascade initiated on endosome R-HSA-975155
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 family signaling R-HSA-446652
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
C-type lectin receptors (CLRs) R-HSA-5621481
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation by c-FLIP R-HSA-3371378
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Regulation of TNFR1 signaling R-HSA-5357905
Diseases of programmed cell death R-HSA-9645723
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
CASP8 activity is inhibited R-HSA-5218900
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Innate Immune System R-HSA-168249
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Immune System R-HSA-168256
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptotic execution phase R-HSA-75153
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Cytokine Signaling in Immune system R-HSA-1280215
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 family signaling R-HSA-446652
Apoptotic cleavage of cellular proteins R-HSA-111465
NOD1/2 Signaling Pathway R-HSA-168638
Signal Transduction R-HSA-162582
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Interleukin-1 signaling R-HSA-9020702
TNFR1-induced proapoptotic signaling R-HSA-5357786
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
MyD88 cascade initiated on plasma membrane R-HSA-975871
Regulated Necrosis R-HSA-5218859
Apoptosis R-HSA-109581
Signaling by Interleukins R-HSA-449147
Regulation of necroptotic cell death R-HSA-5675482
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
RIPK1-mediated regulated necrosis R-HSA-5213460
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TNF signaling R-HSA-75893
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TRAIL signaling R-HSA-75158
Intrinsic Pathway for Apoptosis R-HSA-109606
Programmed Cell Death R-HSA-5357801
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Dimerization of procaspase-8 R-HSA-69416
Disease R-HSA-1643685
FasL/ CD95L signaling R-HSA-75157
TNFR1-induced proapoptotic signaling R-HSA-5357786
C-type lectin receptors (CLRs) R-HSA-5621481
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 dependent cascade initiated on endosome R-HSA-975155
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Innate Immune System R-HSA-168249
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
RIPK1-mediated regulated necrosis R-HSA-5213460
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TNF signaling R-HSA-75893
CLEC7A (Dectin-1) signaling R-HSA-5607764
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Regulation by c-FLIP R-HSA-3371378
Immune System R-HSA-168256
Diseases of programmed cell death R-HSA-9645723
Apoptotic execution phase R-HSA-75153
Regulation of NF-kappa B signaling R-HSA-9758274
Programmed Cell Death R-HSA-5357801
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
TRIF-mediated programmed cell death R-HSA-2562578
CLEC7A/inflammasome pathway R-HSA-5660668
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Disease R-HSA-1643685
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAIL signaling R-HSA-75158
Regulated Necrosis R-HSA-5218859
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Cytokine Signaling in Immune system R-HSA-1280215
Signal Transduction R-HSA-162582
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Apoptotic cleavage of cellular proteins R-HSA-111465
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Regulation of necroptotic cell death R-HSA-5675482
NOD1/2 Signaling Pathway R-HSA-168638
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88-independent TLR4 cascade R-HSA-166166
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
CLEC7A (Dectin-1) signaling R-HSA-5607764
TRIF-mediated programmed cell death R-HSA-2562578
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Apoptotic cleavage of cellular proteins R-HSA-111465
TNFR1-induced proapoptotic signaling R-HSA-5357786
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Regulation by c-FLIP R-HSA-3371378
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
C-type lectin receptors (CLRs) R-HSA-5621481
TRAIL signaling R-HSA-75158
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TNF signaling R-HSA-75893
Interleukin-1 family signaling R-HSA-446652
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Disease R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Death Receptor Signaling R-HSA-73887
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic execution phase R-HSA-75153
Regulation of TNFR1 signaling R-HSA-5357905
MyD88 cascade initiated on plasma membrane R-HSA-975871
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll-like Receptor Cascades R-HSA-168898
Dimerization of procaspase-8 R-HSA-69416
NOD1/2 Signaling Pathway R-HSA-168638
Immune System R-HSA-168256
Signaling by Interleukins R-HSA-449147
Regulation of NF-kappa B signaling R-HSA-9758274
Intrinsic Pathway for Apoptosis R-HSA-109606
Regulated Necrosis R-HSA-5218859
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Regulation of necroptotic cell death R-HSA-5675482
MyD88-independent TLR4 cascade R-HSA-166166
FasL/ CD95L signaling R-HSA-75157
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
CLEC7A/inflammasome pathway R-HSA-5660668
Apoptosis R-HSA-109581
C-type lectin receptors (CLRs) R-HSA-5621481
Death Receptor Signaling R-HSA-73887
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNFR1-induced proapoptotic signaling R-HSA-5357786
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
CLEC7A (Dectin-1) signaling R-HSA-5607764
MyD88 dependent cascade initiated on endosome R-HSA-975155
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic cleavage of cellular proteins R-HSA-111465
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Immune System R-HSA-168256
Programmed Cell Death R-HSA-5357801
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NOD1/2 Signaling Pathway R-HSA-168638
Cytokine Signaling in Immune system R-HSA-1280215
Disease R-HSA-1643685
Signal Transduction R-HSA-162582
Interleukin-1 family signaling R-HSA-446652
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
CLEC7A/inflammasome pathway R-HSA-5660668
MyD88-independent TLR4 cascade R-HSA-166166
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
CASP8 activity is inhibited R-HSA-5218900
Apoptotic execution phase R-HSA-75153
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Innate Immune System R-HSA-168249
Regulation of necroptotic cell death R-HSA-5675482
Regulation of NF-kappa B signaling R-HSA-9758274
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Dimerization of procaspase-8 R-HSA-69416
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Apoptosis R-HSA-109581
FasL/ CD95L signaling R-HSA-75157
TRAIL signaling R-HSA-75158
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Toll-like Receptor Cascades R-HSA-168898
MyD88 cascade initiated on plasma membrane R-HSA-975871
TRIF-mediated programmed cell death R-HSA-2562578
Signaling by Interleukins R-HSA-449147
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Interleukin-1 signaling R-HSA-9020702
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Diseases of programmed cell death R-HSA-9645723
Regulation of TNFR1 signaling R-HSA-5357905
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
CLEC7A/inflammasome pathway R-HSA-5660668
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulation of NF-kappa B signaling R-HSA-9758274
CLEC7A (Dectin-1) signaling R-HSA-5607764
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
TRIF-mediated programmed cell death R-HSA-2562578
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
MyD88 cascade initiated on plasma membrane R-HSA-975871
MyD88-independent TLR4 cascade R-HSA-166166
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Regulation by c-FLIP R-HSA-3371378
Signal Transduction R-HSA-162582
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
RIPK1-mediated regulated necrosis R-HSA-5213460
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
TNF signaling R-HSA-75893
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88 dependent cascade initiated on endosome R-HSA-975155
Disease R-HSA-1643685
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Apoptosis R-HSA-109581
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Toll-like Receptor Cascades R-HSA-168898
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Regulation of necroptotic cell death R-HSA-5675482
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Apoptotic execution phase R-HSA-75153
Programmed Cell Death R-HSA-5357801
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TRAIL signaling R-HSA-75158
FasL/ CD95L signaling R-HSA-75157
CASP8 activity is inhibited R-HSA-5218900
Innate Immune System R-HSA-168249
Dimerization of procaspase-8 R-HSA-69416
Death Receptor Signaling R-HSA-73887
Interleukin-1 signaling R-HSA-9020702
Diseases of programmed cell death R-HSA-9645723
Immune System R-HSA-168256
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Cytokine Signaling in Immune system R-HSA-1280215
Apoptotic cleavage of cellular proteins R-HSA-111465
Regulated Necrosis R-HSA-5218859
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
C-type lectin receptors (CLRs) R-HSA-5621481
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
TNFR1-induced proapoptotic signaling R-HSA-5357786
MyD88-independent TLR4 cascade R-HSA-166166
Regulation by c-FLIP R-HSA-3371378
Regulated Necrosis R-HSA-5218859
FasL/ CD95L signaling R-HSA-75157
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Signal Transduction R-HSA-162582
Cytokine Signaling in Immune system R-HSA-1280215
Regulation of NF-kappa B signaling R-HSA-9758274
Diseases of programmed cell death R-HSA-9645723
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Immune System R-HSA-168256
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Interleukin-1 family signaling R-HSA-446652
CASP8 activity is inhibited R-HSA-5218900
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Apoptosis R-HSA-109581
Regulation of necroptotic cell death R-HSA-5675482
Programmed Cell Death R-HSA-5357801
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Interleukin-1 signaling R-HSA-9020702
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Innate Immune System R-HSA-168249
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
CLEC7A (Dectin-1) signaling R-HSA-5607764
Disease R-HSA-1643685
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Apoptotic execution phase R-HSA-75153
NOD1/2 Signaling Pathway R-HSA-168638
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
CLEC7A/inflammasome pathway R-HSA-5660668
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
RIPK1-mediated regulated necrosis R-HSA-5213460
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 cascade initiated on plasma membrane R-HSA-975871
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
TRAIL signaling R-HSA-75158
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
MyD88 dependent cascade initiated on endosome R-HSA-975155
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Intrinsic Pathway for Apoptosis R-HSA-109606
Signaling by Interleukins R-HSA-449147
Dimerization of procaspase-8 R-HSA-69416
TRIF-mediated programmed cell death R-HSA-2562578
C-type lectin receptors (CLRs) R-HSA-5621481
Toll-like Receptor Cascades R-HSA-168898
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
MyD88 dependent cascade initiated on endosome R-HSA-975155
Immune System R-HSA-168256
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRAIL signaling R-HSA-75158
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Signal Transduction R-HSA-162582
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Signaling by Interleukins R-HSA-449147
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Innate Immune System R-HSA-168249
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
RIPK1-mediated regulated necrosis R-HSA-5213460
Cytokine Signaling in Immune system R-HSA-1280215
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88-independent TLR4 cascade R-HSA-166166
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Disease R-HSA-1643685
Regulated Necrosis R-HSA-5218859
TNFR1-induced proapoptotic signaling R-HSA-5357786
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Regulation of NF-kappa B signaling R-HSA-9758274
Apoptotic execution phase R-HSA-75153
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Dimerization of procaspase-8 R-HSA-69416
Regulation of necroptotic cell death R-HSA-5675482
Regulation of TNFR1 signaling R-HSA-5357905
Interleukin-1 signaling R-HSA-9020702
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
C-type lectin receptors (CLRs) R-HSA-5621481
TNF signaling R-HSA-75893
Regulation by c-FLIP R-HSA-3371378
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
NOD1/2 Signaling Pathway R-HSA-168638
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
CASP8 activity is inhibited R-HSA-5218900
Apoptosis R-HSA-109581
Intrinsic Pathway for Apoptosis R-HSA-109606
CLEC7A/inflammasome pathway R-HSA-5660668
Death Receptor Signaling R-HSA-73887
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Diseases of programmed cell death R-HSA-9645723
Interleukin-1 family signaling R-HSA-446652
TRIF-mediated programmed cell death R-HSA-2562578
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
Programmed Cell Death R-HSA-5357801
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
Regulated Necrosis R-HSA-5218859
Dimerization of procaspase-8 R-HSA-69416
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll-like Receptor Cascades R-HSA-168898
FasL/ CD95L signaling R-HSA-75157
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Regulation of TNFR1 signaling R-HSA-5357905
Disease R-HSA-1643685
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
TNF signaling R-HSA-75893
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Signal Transduction R-HSA-162582
MyD88-independent TLR4 cascade R-HSA-166166
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061
TRIF-mediated programmed cell death R-HSA-2562578
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
Regulation of NF-kappa B signaling R-HSA-9758274
CASP8 activity is inhibited R-HSA-5218900
NOD1/2 Signaling Pathway R-HSA-168638
Death Receptor Signaling R-HSA-73887
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Regulation by c-FLIP R-HSA-3371378
TRAIL signaling R-HSA-75158
MyD88 dependent cascade initiated on endosome R-HSA-975155
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
Cytokine Signaling in Immune system R-HSA-1280215
Immune System R-HSA-168256
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
MyD88 cascade initiated on plasma membrane R-HSA-975871
Apoptotic cleavage of cellular proteins R-HSA-111465
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Signaling by Interleukins R-HSA-449147
Intrinsic Pathway for Apoptosis R-HSA-109606
Interleukin-1 family signaling R-HSA-446652
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
Programmed Cell Death R-HSA-5357801
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Apoptotic execution phase R-HSA-75153
RIPK1-mediated regulated necrosis R-HSA-5213460
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
Apoptosis R-HSA-109581
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
Regulation of necroptotic cell death R-HSA-5675482
CLEC7A (Dectin-1) signaling R-HSA-5607764
Interleukin-1 signaling R-HSA-9020702
CLEC7A/inflammasome pathway R-HSA-5660668
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Innate Immune System R-HSA-168249
C-type lectin receptors (CLRs) R-HSA-5621481
Diseases of programmed cell death R-HSA-9645723
TNFR1-induced proapoptotic signaling R-HSA-5357786
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176
Regulation by c-FLIP R-HSA-3371378
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179
Dimerization of procaspase-8 R-HSA-69416
Diseases of programmed cell death R-HSA-9645723
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181
C-type lectin receptors (CLRs) R-HSA-5621481
Regulated Necrosis R-HSA-5218859
Interleukin-1 family signaling R-HSA-446652
Programmed Cell Death R-HSA-5357801
Death Receptor Signaling R-HSA-73887
MyD88 cascade initiated on plasma membrane R-HSA-975871
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928
RIPK1-mediated regulated necrosis R-HSA-5213460
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534
Innate Immune System R-HSA-168249
Signal Transduction R-HSA-162582
Regulation of TNFR1 signaling R-HSA-5357905
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016
Signaling by Interleukins R-HSA-449147
Apoptotic execution phase R-HSA-75153
Cytokine Signaling in Immune system R-HSA-1280215
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138
NOD1/2 Signaling Pathway R-HSA-168638
Apoptotic cleavage of cellular proteins R-HSA-111465
MyD88 dependent cascade initiated on endosome R-HSA-975155
TRAIL signaling R-HSA-75158
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643
Interleukin-1 signaling R-HSA-9020702
Intrinsic Pathway for Apoptosis R-HSA-109606
Toll-like Receptor Cascades R-HSA-168898
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164
Immune System R-HSA-168256
CASP8 activity is inhibited R-HSA-5218900
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870
Defective RIPK1-mediated regulated necrosis R-HSA-9693928
FasL/ CD95L signaling R-HSA-75157
CLEC7A/inflammasome pathway R-HSA-5660668
TNFR1-induced proapoptotic signaling R-HSA-5357786
Disease R-HSA-1643685
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138
TRIF-mediated programmed cell death R-HSA-2562578
TNF signaling R-HSA-75893
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108
CLEC7A (Dectin-1) signaling R-HSA-5607764
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543
Regulation of NF-kappa B signaling R-HSA-9758274
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347
MyD88-independent TLR4 cascade R-HSA-166166
Regulation of necroptotic cell death R-HSA-5675482
Apoptosis R-HSA-109581
TRIF(TICAM1)-mediated TLR4 signaling R-HSA-937061

Expression Atlas ENSG00000064012
LRG display in Ensembl gene LRG_34
NCBI gene (formerly Entrezgene) 841
GeneCards 1509
HGNC Symbol HGNC:1509
MIM gene 601763
MIM morbid 607271
UniProtKB Gene Name Q14790
WikiGene 841