(E)-2-METHOXYIMINO-N-METHYL-2-(2-PHENOXYPHENYL)-ACETAMIDE

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UNII 6OH8UHE3ZA
Source Gaulton A, Kale N, van Westen GJ, Bellis LJ, Bento AP, Davies M, Hersey A, Papadatos G, Forster M, Wege P, Overington JP. A large-scale crop protection bioassay data set. Sci Data. 2015 Jul 7;2:150032. Read more ...

Structure

InChI Key HIIRDDUVRXCDBN-SDXDJHTJSA-N
Smiles CNC(=O)\C(=N/OC)\c1ccccc1Oc2ccccc2
InChI
InChI=1S/C16H16N2O3/c1-17-16(19)15(18-20-2)13-10-6-7-11-14(13)21-12-8-4-3-5-9-12/h3-11H,1-2H3,(H,17,19)/b18-15-

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H16N2O3
Molecular Weight 284.31
AlogP 2.59
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 59.92
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 21.0
Assay Description Organism Bioactivity Reference
Drug level in Oryza sativa (rice) plant leaf at 18 g/a after 10 days Oryza sativa 20.0 ppm
Drug level in Oryza sativa (rice) plant leaf at 18 g/a up to 42 days Oryza sativa 2.0 ppm
Drug level in Oryza sativa (rice) plant root at 18 g/a up to 42 days Oryza sativa 2.0 ppm
Antifungal activity against Magnaporthe oryzae in fourth-leaf stage of rice plant assessed as appressorial formation at 9 g/a after 24 hr (Rvb = 90.4 +/- 5.6%) Magnaporthe oryzae 92.2 %
Antifungal activity against Magnaporthe oryzae in fourth-leaf stage of rice plant assessed as appressorial formation at 18 g/a after 24 hr (Rvb = 90.4 +/- 5.6%) Magnaporthe oryzae 91.2 %
Antifungal activity against Magnaporthe oryzae in fourth-leaf stage of rice plant assessed as appressorial formation at 36 g/a after 24 hr (Rvb = 90.4 +/- 5.6%) Magnaporthe oryzae 91.9 %
Antifungal activity against Magnaporthe oryzae in fourth-leaf stage of rice plant assessed as spore germination at 9 g/a after 24 hr (Rvb = 97.2 +/- 2.7%) Magnaporthe oryzae 97.1 %
Antifungal activity against Magnaporthe oryzae in fourth-leaf stage of rice plant assessed as spore germination at 18 g/a after 24 hr (Rvb = 97.2 +/- 2.7%) Magnaporthe oryzae 96.5 %
Antifungal activity against Magnaporthe oryzae in fourth-leaf stage of rice plant assessed as spore germination at 36 g/a after 24 hr (Rvb = 97.2 +/- 2.7%) Magnaporthe oryzae 96.4 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 125 ppm foliar application 24 hr before inoculation on upper surface of leaf by preventive manner Pseudoperonospora cubensis 70.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 31.3 ppm foliar application 24 hr before inoculation on upper surface of leaf by preventive manner Pseudoperonospora cubensis 0.0 %
Fungicidal activity against Pseudoperonospora cubensis assessed as cucumber downy mildew disease control at 7.8 ppm foliar application 24 hr before inoculation on upper surface of leaf by preventive manner Pseudoperonospora cubensis 0.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 125 ppm foliar application 24 hr before inoculation at 22 +/- 2 degC measured after 3 days by preventive manner Botryotinia fuckeliana 44.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 31.3 ppm foliar application 24 hr before inoculation at 22 +/- 2 degC measured after 3 days by preventive manner Botryotinia fuckeliana 36.0 %
Fungicidal activity against Botryotinia fuckeliana assessed as cucumber gray mold disease control at 7.8 ppm foliar application 24 hr before inoculation at 22 +/- 2 degC measured after 3 days by preventive manner Botryotinia fuckeliana 18.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 125 ppm foliar application 24 hr before inoculation on upper surface of leaf at 23 +/- 2 degC by preventive manner Podosphaera fuliginea 100.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 31.3 ppm foliar application 24 hr before inoculation on upper surface of leaf at 23 +/- 2 degC by preventive manner Podosphaera fuliginea 100.0 %
Fungicidal activity against Podosphaera fuliginea assessed as cucumber powdery mildew control under greenhouse at 7.8 ppm foliar application 24 hr before inoculation on upper surface of leaf at 23 +/- 2 degC by preventive manner Podosphaera fuliginea 40.0 %
Fungicidal activity against Thanatephorus cucumeris assessed as rice sheath blight disease control at 125 ppm foliar application for 24 hr before inoculation at 26 +- 2 measured after 5 days by preventive manner Thanatephorus cucumeris 50.0 %
Fungicidal activity against Thanatephorus cucumeris assessed as rice sheath blight disease control at 31.3 ppm foliar application for 24 hr before inoculation at 26 +- 2 measured after 5 days by preventive manner Thanatephorus cucumeris 0.0 %
Fungicidal activity against Thanatephorus cucumeris assessed as rice sheath blight disease control at 7.8 ppm foliar application for 24 hr before inoculation at 26 +- 2 measured after 5 days by preventive manner Thanatephorus cucumeris 0.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 125 ppm foliar application for 24 hr before inoculation at 27 +/- 2 degC measured after 5 days by preventive manner Magnaporthe oryzae 50.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 31.3 ppm foliar application for 24 hr before inoculation at 27 +/- 2 degC measured after 5 days by preventive manner Magnaporthe oryzae 30.0 %
Fungicidal activity against Magnaporthe oryzae assessed as rice blast disease control at 7.8 ppm foliar application for 24 hr before inoculation at 27 +/- 2 degC measured after 5 days by preventive manner Magnaporthe oryzae 0.0 %
Fungicidal activity against Cladosporium herbarum assessed as inhibition of mycelial growth by agar dilution method Cladosporium herbarum 41.8 ppm
Fungicidal activity against Magnaporthe oryzae assessed as inhibition of mycelial growth by agar dilution method Magnaporthe oryzae 49.1 ppm
Fungicidal activity against Colletotrichum lagenaria assessed as inhibition of mycelial growth by agar dilution method Colletotrichum lagenaria 61.8 ppm
Fungicidal activity against Fusarium oxysporum assessed as inhibition of mycelial growth by agar dilution method Fusarium oxysporum 58.1 ppm
Fungicidal activity against Alternaria alternata apple pathotype assessed as inhibition of mycelial growth by agar dilution method Alternaria alternata 64.0 ppm
Fungicidal activity against Botryotinia fuckeliana assessed as inhibition of mycelial growth by agar dilution method Botryotinia fuckeliana 1.7 ppm
Fungicidal activity against Athelia rolfsii assessed as inhibition of mycelial growth by agar dilution method Athelia rolfsii 41.1 ppm
Fungicidal activity against Glomerella cingulata assessed as inhibition of mycelial growth by agar dilution method Glomerella cingulata 16.2 ppm
Fungicidal activity against Sclerotinia sclerotiorum assessed as inhibition of mycelial growth by agar dilution method Sclerotinia sclerotiorum 11.9 ppm
Fungicidal activity against Pythium aphanidermatum assessed as inhibition of mycelial growth by agar dilution method Pythium aphanidermatum 28.1 ppm

Cross References

Resources Reference
ChEMBL CHEMBL2286642
FDA SRS 6OH8UHE3ZA
PubChem 9576038
SureChEMBL SCHEMBL912965
ZINC ZINC38810687
CONTENTS