PHOSPHINE

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UNII FW6947296I
Source Gaulton A, Kale N, van Westen GJ, Bellis LJ, Bento AP, Davies M, Hersey A, Papadatos G, Forster M, Wege P, Overington JP. A large-scale crop protection bioassay data set. Sci Data. 2015 Jul 7;2:150032. Read more ...

Structure

InChI Key XYFCBTPGUUZFHI-UHFFFAOYSA-N
Smiles P
InChI
InChI=1S/H3P/h1H3

Physicochemical Descriptors

Property Name Value
Molecular Formula H3P
Molecular Weight 34.0
AlogP -0.31
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 0.0
Polar Surface Area 33.0
Molecular species None
Aromatic Rings 0.0
Heavy Atoms 1.0
Assay Description Organism Bioactivity Reference
Insecticidal activity against third-instar larval stage of Tribolium confusum (confused flour beetle) assessed as change in the integument colour to dark in the middle area with slight effect toward both ends at 5 mg/ml applied as fumes measured after 24 hr by light microscopic analysis Tribolium confusum None
Insecticidal activity against third-instar larval stage of Tribolium confusum (confused flour beetle) assessed as vacuolization of the mitochondrial matrix in regenerative nidi cells of the midgut at 5 mg/l applied as fumes measured after 24 hr by electron microscopic analysis Tribolium confusum None
Insecticidal activity against third-instar larval stage of Tribolium confusum (confused flour beetle) assessed as vacuolization of the mitochondrial matrix in columnar cells of the midgut at 5 mg/l applied as fumes measured after 24 hr by electron microscopic analysis Tribolium confusum None
Insecticidal activity against third-instar larval stage of Tribolium confusum (confused flour beetle) assessed as mitochondria with reduced quantity of cristae, lower electron dense matrix, vacuolization and rarefaction of mitochondrial matrix in the epithelial cells of epidermal layer in the integument at 5 mg/l applied as fumes measured after 24 hr by electron microscopic analysis Tribolium confusum None
Insecticidal activity against third-instar larval stage of Tribolium confusum (confused flour beetle) assessed as changes in posterior and middle regions of midgut with attatched malphigian tubules at 5 mg/l applied as fumes measured after 24 hr by light microscopy Tribolium confusum None
Insecticidal activity against larvae of Tribolium confusum (confused flour beetle) in broken wheat assessed as mortality at 5 mg/l applied as fumes for 72 hr measured after 14 days by fumigation bioassay Tribolium confusum 100.0 %
Insecticidal activity against adult Tribolium confusum (confused flour beetle) in broken wheat assessed as mortality at 5 mg/l applied as fumes for 72 hr measured after 14 days by fumigation bioassay Tribolium confusum 100.0 %
Insecticidal activity against adult Sitophilus oryzae (rice weevil) in wheat grain assessed as mortality at 5 mg/l applied as fumes for 72 hr measured after 7 days by fumigation bioassay Sitophilus oryzae 100.0 %
Insecticidal activity against adult Sitophilus zeamais assessed as mortality after 24 hr by fumigation assay Sitophilus zeamais 0.006 ug.mL-1
Resistance index, ratio of LT99.9 for phosphine-strongly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR to LT99.9 for phosphine-weakly resistant rusty grain beetle Lab-WR Cryptolestes ferrugineus 79.0
Resistance index, ratio of LT99.9 for phosphine-strongly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR to LT99.9 for rusty grain beetle Lab-S Cryptolestes ferrugineus 1630.0
Resistance index, ratio of LT99.9 for phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR to LT99.9 for rusty grain beetle Lab-S Cryptolestes ferrugineus 21.0
Insecticidal activity against phosphine-strongly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR at 2 mg/L by time-to-knock down bioassay Cryptolestes ferrugineus 22783.0 min
Insecticidal activity against phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR at 2 mg/L by time-to-knock down bioassay Cryptolestes ferrugineus 809.6 min
Insecticidal activity against Cryptolestes ferrugineus (rusty grain beetle) Lab-S at 2 mg/L by time-to-knock down bioassay Cryptolestes ferrugineus 14.65 min
Resistance index, ratio of LC50 for phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR to LC50 for rusty grain beetle Lab-S after 72 hr Cryptolestes ferrugineus 1457.8
Resistance index, ratio of LC50 for phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR to LC50 for rusty grain beetle Lab-S after 48 hr Cryptolestes ferrugineus 1341.2
Resistance index, ratio of LC50 for phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 7.3
Resistance index, ratio of LC50 for phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR to LC50 for rusty grain beetle Lab-S after 72 hr Cryptolestes ferrugineus 8.8
Insecticidal activity against phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR after 72 hr by FAO method Cryptolestes ferrugineus 30.07 mg/L Insecticidal activity against phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR after 72 hr by FAO method Cryptolestes ferrugineus 6.37 ug.mL-1
Insecticidal activity against phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR after 48 hr by FAO method Cryptolestes ferrugineus 37.68 mg/L Insecticidal activity against phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR after 48 hr by FAO method Cryptolestes ferrugineus 6.57 ug.mL-1
Resistance index, ratio of LC50 for phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR to LC50 for rusty grain beetle Lab-S after 48 hr Cryptolestes ferrugineus 11.4
Insecticidal activity against phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR after 144 hr by FAO method Cryptolestes ferrugineus 0.06 mg/L Insecticidal activity against phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR after 144 hr by FAO method Cryptolestes ferrugineus 0.022 ug.mL-1
Insecticidal activity against phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR after 72 hr by FAO method Cryptolestes ferrugineus 0.15 mg/L Insecticidal activity against phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR after 72 hr by FAO method Cryptolestes ferrugineus 0.037 ug.mL-1
Insecticidal activity against phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR after 48 hr by FAO method Cryptolestes ferrugineus 0.26 mg/L Insecticidal activity against phosphine-weakly resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-WR after 48 hr by FAO method Cryptolestes ferrugineus 0.056 ug.mL-1
Insecticidal activity against Cryptolestes ferrugineus (rusty grain beetle) Lab-S after 72 hr by FAO method Cryptolestes ferrugineus 0.008 mg/L Insecticidal activity against Cryptolestes ferrugineus (rusty grain beetle) Lab-S after 72 hr by FAO method Cryptolestes ferrugineus 0.004 ug.mL-1
Insecticidal activity against Cryptolestes ferrugineus (rusty grain beetle) Lab-S after 48 hr by FAO method Cryptolestes ferrugineus 0.009 mg/L Insecticidal activity against Cryptolestes ferrugineus (rusty grain beetle) Lab-S after 48 hr by FAO method Cryptolestes ferrugineus 0.005 ug.mL-1
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QQCF691 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 447.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF134 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 407.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF130 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 473.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF129 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 500.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF122 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 587.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF110 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 326.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF104 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 403.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF102 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 436.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF101 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 373.0
Resistance index, ratio of LC50 for strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF83 to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 433.0
Resistance index, ratio of LC50 for phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR to LC50 for rusty grain beetle Lab-S after 144 hr Cryptolestes ferrugineus 560.0
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QQCF691 after 144 hr by FAO method Cryptolestes ferrugineus 2.9 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QQCF691 after 144 hr by FAO method Cryptolestes ferrugineus 1.34 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF134 after 144 hr by FAO method Cryptolestes ferrugineus 2.93 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF134 after 144 hr by FAO method Cryptolestes ferrugineus 1.22 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF130 after 144 hr by FAO method Cryptolestes ferrugineus 3.42 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF130 after 144 hr by FAO method Cryptolestes ferrugineus 1.42 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF129 after 144 hr by FAO method Cryptolestes ferrugineus 3.82 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF129 after 144 hr by FAO method Cryptolestes ferrugineus 1.5 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF122 after 144 hr by FAO method Cryptolestes ferrugineus 3.92 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF122 after 144 hr by FAO method Cryptolestes ferrugineus 1.77 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF110 after 144 hr by FAO method Cryptolestes ferrugineus 2.95 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF110 after 144 hr by FAO method Cryptolestes ferrugineus 0.97 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF104 after 144 hr by FAO method Cryptolestes ferrugineus 3.75 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF104 after 144 hr by FAO method Cryptolestes ferrugineus 1.21 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF102 after 144 hr by FAO method Cryptolestes ferrugineus 3.08 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF102 after 144 hr by FAO method Cryptolestes ferrugineus 1.31 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF101 after 144 hr by FAO method Cryptolestes ferrugineus 3.46 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF101 after 144 hr by FAO method Cryptolestes ferrugineus 1.12 ug.mL-1
Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF83 after 144 hr by FAO method Cryptolestes ferrugineus 3.25 mg/L Insecticidal activity against strongly phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) QNCF83 after 144 hr by FAO method Cryptolestes ferrugineus 1.3 ug.mL-1
Insecticidal activity against phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR after 144 hr by FAO method Cryptolestes ferrugineus 3.62 mg/L Insecticidal activity against phosphine-resistant Cryptolestes ferrugineus (rusty grain beetle) Lab-StR after 144 hr by FAO method Cryptolestes ferrugineus 1.66 ug.mL-1
Insecticidal activity against Cryptolestes ferrugineus (rusty grain beetle) Lab-S after 144 hr by FAO method Cryptolestes ferrugineus 0.01 mg/L Insecticidal activity against Cryptolestes ferrugineus (rusty grain beetle) Lab-S after 144 hr by FAO method Cryptolestes ferrugineus 0.003 ug.mL-1

Cross References

Resources Reference
ChEMBL CHEMBL2227836
FDA SRS FW6947296I
PubChem 24404
SureChEMBL SCHEMBL68
CONTENTS