Selectivity ratio of relative toxicity against po dosed rat to relative efficacy against Gibberella zeae
|
None
|
0.0
|
|
Toxicity in po dosed Rattus norvegicus (rat) relative to metconazole
|
Rattus norvegicus
|
0.19
|
|
Antifungal activity against Fusarium graminearum after 8 hr by microscopic analysis relative to prothioconazole
|
Fusarium graminearum
|
0.0
|
|
Growth inhibition of Fusarium graminearum isolate 74B at 10'-4 M after 14 days
|
Fusarium graminearum
|
95.7
%
|
|
Growth inhibition of Fusarium graminearum isolate 137 at 10'-4 M after 14 days
|
Fusarium graminearum
|
99.6
%
|
|
Growth inhibition of Fusarium graminearum isolate 4527b at 10'-4 M after 14 days
|
Fusarium graminearum
|
98.0
%
|
|
Growth inhibition of Fusarium graminearum isolate 123 at 10'-4 M after 14 days
|
Fusarium graminearum
|
95.9
%
|
|
Growth inhibition of Fusarium graminearum isolate 102 at 10'-4 M after 14 days
|
Fusarium graminearum
|
97.1
%
|
|
Growth inhibition of Fusarium graminearum isolate 106 at 10'-4 M after 14 days
|
Fusarium graminearum
|
95.4
%
|
|
Growth inhibition of Fusarium graminearum isolate 37 at 10'-4 M after 14 days
|
Fusarium graminearum
|
98.7
%
|
|
Antifungal activity against Fusarium graminearum isolate 137 after 8 hr by microscopic analysis
|
Fusarium graminearum
|
10800000.0
nM
|
|
Antifungal activity against Fusarium graminearum isolate 106 after 8 hr by microscopic analysis
|
Fusarium graminearum
|
10800000.0
nM
|
|
Antifungal activity against Fusarium graminearum isolate 123 after 8 hr by microscopic analysis
|
Fusarium graminearum
|
10800000.0
nM
|
|
Antifungal activity against Fusarium graminearum isolate 102 after 8 hr by microscopic analysis
|
Fusarium graminearum
|
10800000.0
nM
|
|
Antifungal activity against Fusarium graminearum isolate 37 after 8 hr by microscopic analysis
|
Fusarium graminearum
|
10800000.0
nM
|
|
Toxicity in po dosed Rattus norvegicus (rat)
|
Rattus norvegicus
|
3160.0
mg.kg-1
|
|
Aqueous solubility of the compound assessed per 100 g
|
None
|
0.7
mg
|
|
Resistance index, ratio of EC50 for prochloraz-resistant Oculimacula yallundae isolate ProR2 to EC50 for prochloraz-susceptible Oculimacula yallundae isolate ProS by germ tube elongation inhibition assay
|
Oculimacula yallundae
|
3.0
|
|
Resistance index, ratio of EC50 for prochloraz-resistant Oculimacula yallundae isolate ProR1 to EC50 for prochloraz-susceptible Oculimacula yallundae isolate ProS by germ tube elongation inhibition assay
|
Oculimacula yallundae
|
2.0
|
|
Resistance index, ratio of EC50 for prochloraz-resistant Oculimacula yallundae isolate ProR2 to EC50 for prochloraz-susceptible Oculimacula yallundae isolate ProS by mycelial growth inhibition assay
|
Oculimacula yallundae
|
5.0
|
|
Resistance index, ratio of EC50 for prochloraz-resistant Oculimacula yallundae isolate ProR1 to EC50 for prochloraz-susceptible Oculimacula yallundae isolate ProS by mycelial growth inhibition assay
|
Oculimacula yallundae
|
3.3
|
|
Fungicidal activity against prochloraz-susceptible Oculimacula yallundae isolate ProS assessed as inhibition of germ tube elongation incubated at 19 degC in dark for 48 hr
|
Oculimacula yallundae
|
0.3
ug.mL-1
|
|
Fungicidal activity against prochloraz-susceptible Oculimacula yallundae isolate ProS assessed as inhibition of mycelial growth in presence of 10 g glucose incubated at 19 degC in dark for 4 weeks
|
Oculimacula yallundae
|
0.3
ug.mL-1
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae MDR to EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 by germ tube elongation assay
|
Oculimacula yallundae
|
5.0
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae MDR to EC50 for wild type Oculimacula yallundae TriS by germ tube elongation assay
|
Oculimacula yallundae
|
150.0
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR2 to EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 by germ tube elongation assay
|
Oculimacula yallundae
|
2.0
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR2 to EC50 for wild type Oculimacula yallundae TriS by germ tube elongation assay
|
Oculimacula yallundae
|
60.0
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 to EC50 for wild type Oculimacula yallundae TriS by germ tube elongation assay
|
Oculimacula yallundae
|
30.0
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae MDR to EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 by mycelial growth inhibition assay
|
Oculimacula yallundae
|
2.0
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 to EC50 for wild type Oculimacula yallundae TriS by mycelial growth inhibition assay
|
Oculimacula yallundae
|
3.3
|
|
Selectivity index, ratio of EC50 for Oculimacula acuformis to EC50 for Oculimacula yallundae in presence of 10 g glucose by mycelial growth inhibition assay
|
None
|
2.0
|
|
Fungicidal activity against Oculimacula yallundae assessed as inhibition of mycelial growth in presence of 10 g glucose incubated at 19 degC in dark for 4 weeks
|
Oculimacula yallundae
|
0.15
ug.mL-1
|
|
Fungicidal activity against Oculimacula acuformis assessed as inhibition of mycelial growth in presence of 10 g glucose incubated at 19 degC in dark for 4 weeks
|
Oculimacula acuformis
|
0.3
ug.mL-1
|
|
Selectivity index, ratio of EC50 for Oculimacula acuformis to EC50 for Oculimacula yallundae by germ tube elongation inhibition assay
|
None
|
15.0
|
|
Fungicidal activity against Oculimacula yallundae assessed as inhibition of germ tube elongation incubated at 19 degC in dark for 48 hr
|
Oculimacula yallundae
|
0.02
ug.mL-1
|
|
Fungicidal activity against Oculimacula acuformis assessed as inhibition of germ tube elongation incubated at 19 degC in dark for 48 hr
|
Oculimacula acuformis
|
0.3
ug.mL-1
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR2 to EC50 for wild type Oculimacula yallundae TriS by mycelial growth inhibition assay
|
Oculimacula yallundae
|
3.3
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR2 to EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 by mycelial growth inhibition assay
|
Oculimacula yallundae
|
1.0
|
|
Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae MDR to EC50 for wild type Oculimacula yallundae TriS by mycelial growth inhibition assay
|
Oculimacula yallundae
|
6.7
|
|
Fungicidal activity against Zymoseptoria tritici isolate TAG74-3 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as fungal DNA level at doses > 1/16 recommended field rate measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
None
|
|
Fungicidal activity against Zymoseptoria tritici isolate OP7 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as fungal DNA level at doses > 1/16 recommended field rate measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
None
|
|
Fungicidal activity against Zymoseptoria tritici isolate TAG74-3 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as pycnidia formation at doses > 1/16 recommended field rate measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
None
|
|
Fungicidal activity against Zymoseptoria tritici isolate OP7 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as pycnidia formation at doses > 1/16 recommended field rate measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
None
|
|
Fungicidal activity against Zymoseptoria tritici isolate TAG74-3 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as pycnidia formation at 39.06 ppm measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
None
|
|
Fungicidal activity against Zymoseptoria tritici isolate OP7 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as pycnidia formation at 39.06 ppm measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
None
|
|
Fungicidal activity against Zymoseptoria tritici isolate R10-13 without 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as fungal DNA level at 39.06 ppm measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
400.0
pg
|
|
Fungicidal activity against Zymoseptoria tritici isolate OP6 without 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as fungal DNA level at 39.06 ppm measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
14.0
pg
|
|
Fungicidal activity against Zymoseptoria tritici isolate TAG74-3 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as fungal DNA level at 39.06 ppm measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
9284.0
pg
|
|
Fungicidal activity against Zymoseptoria tritici isolate OP7 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations inoculated on compound pre-treated wheat cultivar Riband seedlings assessed as fungal DNA level at 39.06 ppm measured 21 days post fungal inoculation
|
Zymoseptoria tritici
|
1600.0
pg
|
|
Fungicidal activity against Zymoseptoria tritici isolate TAG74-3 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
1.41
ug.mL-1
|
|
Fungicidal activity against Zymoseptoria tritici isolate OP7 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
0.819
ug.mL-1
|
|
Fungicidal activity against Zymoseptoria tritici isolate TAG1-18 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
0.911
ug.mL-1
|
|
Fungicidal activity against Zymoseptoria tritici isolate V18 with 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
0.759
ug.mL-1
|
|
Fungicidal activity against Zymoseptoria tritici isolate OP6 without 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
0.085
ug.mL-1
|
|
Fungicidal activity against Zymoseptoria tritici isolate R10-13 without 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
0.091
ug.mL-1
|
|
Fungicidal activity against Zymoseptoria tritici isolate R03-54 without 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
0.092
ug.mL-1
|
|
Fungicidal activity against Zymoseptoria tritici isolate R03-29 without 120 bp insertion expressing CYP51 variant with combination of L50S, S188N, I381V, deltaY459/G460 and N513K mutations assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
0.067
ug.mL-1
|
|
Fungicidal activity against Zymoseptoria tritici isolate IPO323 without 120 bp insertion expressing wild type CYP51 assessed as fungal growth inhibition
|
Zymoseptoria tritici
|
0.0015
ug.mL-1
|
|