CAMPHOR

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Synonyms
UNII N20HL7Q941
Source Gaulton A, Kale N, van Westen GJ, Bellis LJ, Bento AP, Davies M, Hersey A, Papadatos G, Forster M, Wege P, Overington JP. A large-scale crop protection bioassay data set. Sci Data. 2015 Jul 7;2:150032. Read more ...

Structure

InChI Key DSSYKIVIOFKYAU-XCBNKYQSSA-N
Smiles CC1(C)[C@@H]2CC[C@@]1(C)C(=O)C2
InChI
InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H16O
Molecular Weight 152.23
AlogP 2.08
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 0.0
Polar Surface Area 17.07
Molecular species None
Aromatic Rings 0.0
Heavy Atoms 11.0
Assay Description Organism Bioactivity Reference
Antitussive activity against crtric acid-induced cough in Cavia porcellus (guinea pig) model assessed as reduction in cough response at 250 to 500 ug/ml for 5 min through aerosol prior to exposure of aerosolized citric acid for 10 min Cavia porcellus None
Antitussive activity against crtric acid-induced cough in Cavia porcellus (guinea pig) model assessed as increase in cough latency at 500 ug/ml for 5 min through aerosol prior to exposure of aerosolized citric acid for 10 min Cavia porcellus None
Antitussive activity against crtric acid-induced cough in Cavia porcellus (guinea pig) model assessed as cough response at 125 ug/ml for 5 min through aerosol prior to exposure of aerosolized citric acid for 10 min Cavia porcellus None
Antitussive activity against crtric acid-induced cough in Cavia porcellus (guinea pig) model assessed as cough latency at 125 to 250 ug/ml for 5 min through aerosol prior to exposure of aerosolized citric acid for 10 min Cavia porcellus None
Antifungal activity against Colletotrichum gloeosporioides assessed as growth inhibition at 4 uL in 2 mM acetone by direct bioautography Colletotrichum gloeosporioides 0.0 mm
Antifungal activity against Colletotrichum fragariae assessed as growth inhibition at 4 uL in 2 mM acetone by direct bioautography Colletotrichum fragariae 0.0 mm
Antifungal activity against Colletotrichum acutatum assessed as growth inhibition at 4 uL in 2 mM acetone by direct bioautography Colletotrichum acutatum 0.0 mm
Insecticidal activity against adult Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 96 hr relative to control Leptinotarsa decemlineata 93.3 %
Antifeedant activity against Spodoptera littoralis fed on compound treated artificial diet assessed as food ingested by choice feeding assay relative to control Spodoptera littoralis 83.0 %
Antifeedant activity against Spodoptera littoralis fed on compound treated artificial diet assessed as larval weight gain by choice feeding assay relative to control Spodoptera littoralis 97.0 %
Antifeedant activity against apterous adult Myzus persicae (green peach aphid) fed on on compound treated bell pepper assessed as settling on leaf by choice feeding assay (Rvb = 52 to 70%) Myzus persicae 40.0 %
Insecticidal activity against adult Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 48 hr relative to control Leptinotarsa decemlineata 43.3 %
Insecticidal activity against adult Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 24 hr relative to control Leptinotarsa decemlineata 13.3 %
Insecticidal activity against adult Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 12 hr relative to control Leptinotarsa decemlineata 6.7 %
Insecticidal activity against adult Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 96 hr relative to control Leptinotarsa decemlineata 56.7 %
Insecticidal activity against adult Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 48 hr relative to control Leptinotarsa decemlineata 36.7 %
Insecticidal activity against adult Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 24 hr relative to control Leptinotarsa decemlineata 0.0 %
Insecticidal activity against adult Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 12 hr relative to control Leptinotarsa decemlineata 0.0 %
Insecticidal activity against third-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 96 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 36.7 %
Insecticidal activity against third-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 48 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 33.3 %
Insecticidal activity against third-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 24 hr relative to control Leptinotarsa decemlineata 30.0 %
Insecticidal activity against third-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 12 hr relative to control Leptinotarsa decemlineata 26.7 %
Insecticidal activity against third-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 96 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 6.7 %
Insecticidal activity against third-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 48 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 6.7 %
Insecticidal activity against third-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 24 hr relative to control Leptinotarsa decemlineata 0.0 %
Insecticidal activity against third-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 12 hr relative to control Leptinotarsa decemlineata 0.0 %
Insecticidal activity against second-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 96 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 86.7 %
Insecticidal activity against second-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 48 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 86.7 %
Insecticidal activity against second-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 24 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 83.3 %
Insecticidal activity against second-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 12 hr relative to control Leptinotarsa decemlineata 36.7 %
Insecticidal activity against second-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 96 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 70.0 %
Insecticidal activity against second-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 48 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 63.3 %
Insecticidal activity against second-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 24 hr (Rvb = 3.3 +/- 3.3%) Leptinotarsa decemlineata 46.7 %
Insecticidal activity against second-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 12 hr relative to control Leptinotarsa decemlineata 13.3 %
Insecticidal activity against first-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 48 hr relative to control Leptinotarsa decemlineata 23.3 %
Insecticidal activity against first-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 96 hr relative to control Leptinotarsa decemlineata 86.7 %
Insecticidal activity against first-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 48 hr relative to control Leptinotarsa decemlineata 86.7 %
Insecticidal activity against first-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 24 hr relative to control Leptinotarsa decemlineata 53.3 %
Insecticidal activity against first-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 20 mg after 12 hr relative to control Leptinotarsa decemlineata 30.0 %
Insecticidal activity against first-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 96 hr relative to control Leptinotarsa decemlineata 76.7 %
Insecticidal activity against first-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 24 hr relative to control Leptinotarsa decemlineata 0.0 %
Insecticidal activity against first-instar larval stage of Leptinotarsa decemlineata infested potato leaves assessed as mortality at 10 mg after 12 hr relative to control Leptinotarsa decemlineata 0.0 %
Mixed type inhibition of Electrophorus electricus (electric eel) acetylcholinesteraseAChE using acetylthiocholine iodide substrate by Ellman method based colorimetry Electrophorus electricus None
Reversible inhibition of Electrophorus electricus (electric eel)acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry Electrophorus electricus None
Inhibition of Electrophorus electricus (electric eel) acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry Electrophorus electricus 50000.0 nM
Induction of growth of Fusarium graminearum after 4 to 12 days Fusarium graminearum None
Antimicrobial activity against Candida albicans ATCC 14053 assessed as growth inhibition after 24 hr by broth microdilution method Candida albicans 900.0 uL/ml
Antimicrobial activity against Pseudomonas aeruginosa ATCC 9027 assessed as growth inhibition after 24 hr by broth microdilution method Pseudomonas aeruginosa 900.0 uL/ml
Antimicrobial activity against Escherichia coli ATCC 8739 assessed as growth inhibition after 24 hr by broth microdilution method Escherichia coli ATCC 8739 900.0 uL/ml
Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 assessed as growth inhibition after 24 hr by broth microdilution method Staphylococcus epidermidis ATCC 12228 900.0 uL/ml
Antimicrobial activity against Staphylococcus aureus ATCC 6538 assessed as growth inhibition after 24 hr by broth microdilution method Staphylococcus aureus 900.0 uL/ml
Antifungal activity against Rhizoctonia solani assessed as mycelial growth inhibition after 4 to 12 days Rhizoctonia solani None
Antifungal activity against Fusarium culmorum assessed as mycelial growth inhibition after 4 to 12 days Fusarium culmorum None
Antifungal activity against Fusarium graminearum assessed as mycelial growth inhibition after 4 to 12 days Fusarium graminearum None
Antifungal activity against Fusarium oxysporum f. sp. lycopersici assessed as mycelial growth inhibition after 4 to 12 days Fusarium oxysporum f. sp. lycopersici None
Antifungal activity against Botryotinia fuckeliana assessed as mycelial growth inhibition after 4 to 12 days Botryotinia fuckeliana None
Contact insecticidal activity against cotton leafworm Spodoptera littoralis third-instar larvae exposed to 1 mg/larva compound application through dorsum of larvae followed by feeding on fresh castor bean leaves assessed as insect mortality after 24 hr Spodoptera littoralis None
Fumigant insecticidal activity against cotton leafworm Spodoptera littoralis third-instar larvae fed on fresh castor bean leaves assessed as insect mortality after 24 hr Spodoptera littoralis 5.61 ug.mL-1
Fumigant molluscicidal activity against Theba pisana (white garden snail) assessed as snail mortality after 24 hr Theba pisana 7.98 ug.mL-1
Contact molluscicidal activity against Theba pisana (white garden snail ) exposed to compound throgh application to surface of snail body inside shell assessed as compound level per snail causing snail mortality after 24 hr Theba pisana 89.15 ug
Toxicity to Musca domestica (house fly) applied to pronotum assessed as compound level per fly causing insect mortality measured after 24 hr Musca domestica 149.5 ug
Displacement of [3H]TBOB binding to GABA receptor in Musca domestica (house fly) heads homogenates assessed as [3H]TBOB binding at 500 uM incubated for 90 min by scintillation counting method Musca domestica 70.0 %
Antimicrobial activity against Corticium sp. assessed as inhibition of mycelial growth on potato dextrose agar at 1000 ppm at 27 degC measured after 4 days Corticium 22.1 %
Antimicrobial activity against Corticium sp. assessed as inhibition of mycelial growth on potato dextrose agar at 100 ppm at 27 degC measured after 4 days Corticium 0.4 %
Antimicrobial activity against Pythium sp. assessed as inhibition of mycelial growth on potato dextrose agar at 1000 ppm at 27 degC measured after 4 days Pythium 9.3 %
Antimicrobial activity against Pythium sp. assessed as inhibition of mycelial growth on potato dextrose agar at 100 ppm at 27 degC measured after 4 days Pythium 0.0 %

Cross References

Resources Reference
ChEMBL CHEMBL504760
FDA SRS N20HL7Q941
PDB CAM
PubChem 159055
SureChEMBL SCHEMBL16069
ZINC ZINC00967520
CONTENTS