|
Nematotoxic activity against freshly hatched Meloidogyne incognita J2 (root-knot nematode) isolated from tomato roots assessed as induction of nematode paralysis measured 24 hr after immersion in compound test solutions
|
Meloidogyne incognita
|
1000.0
ug.mL-1
|
|
Journal : J Agric Food Chem
Title : Nematotoxic phenolic compounds from Melia azedarach against Meloidogyne incognita.
Year : 2012
Volume : 60
Issue : 47
First Page : 11675
Last Page : 11680
Authors : Aoudia H, Ntalli N, Aissani N, Yahiaoui-Zaidi R, Caboni P.
Abstract : In the present study, evaluated was the paralysis activity of whole Italian and Algerian Melia azedarach, commonly known as chinaberry, fruits and parts (seeds, wood, and kernels) against Meloidogyne incognita second stage juveniles (J(2)). The paralysis activity was evaluated in vitro after 1 h and 1 day immersion periods of nematodes in test solutions. Phenolic constituent components of the extracts were identified and quantified by high-performance liquid chromatography-mass spectrometry, while confirmation was performed by high-performance liquid chromatography-diode array. The water extract of the Italian M. azedarach fruit pulp (IPWE) showed significant nematicidal activity (EC(50/48h) = 955 μg/mL) and among its active ingredient components were p-coumaric acid and p-hydroxybenzoic acid (EC(50/48h) = 840 and 871 μg/mL, respectively). This is the first report of the nematicidal activity of M. azedarach pulp water extract and phenolic acids against the root knot nematode M. incognita.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 1% under light conditions measured 48 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
100.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.125% under dark conditions measured 72 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
70.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.25% under dark conditions measured 72 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
70.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.5% under light conditions measured 48 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
100.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.125% under dark conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.25% under dark conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.5% under dark conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 1% under dark conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 2% under dark conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 5% under dark conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.125% under light conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.25% under light conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.5% under light conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 1% under light conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 2% under light conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 5% under light conditions measured 5 to 60 min post dose by stereoscopic microscopy
|
Heterodera zeae
|
None
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.125% under dark conditions measured 48 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
70.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.25% under dark conditions measured 48 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
70.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.125% under dark conditions measured 24 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
0.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.25% under dark conditions measured 24 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
0.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.5% under dark conditions measured 24 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
100.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 1% under dark conditions measured 24 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
100.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.125% under light conditions measured 48 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
100.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.25% under light conditions measured 48 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
100.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.125% under light conditions measured 24 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
0.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.25% under light conditions measured 24 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
0.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 0.5% under light conditions measured 24 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
100.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Nematicidal activity against Heterodera zeae infective stage larvae assessed as nematode mortality at 1% under light conditions measured 24 hr post dose by stereoscopic microscopy
|
Heterodera zeae
|
100.0
%
|
|
Journal : J Agric Food Chem
Title : Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae.
Year : 2011
Volume : 59
Issue : 17
First Page : 9080
Last Page : 9093
Authors : Faizi S, Fayyaz S, Bano S, Iqbal EY, Lubna, Siddiqi H, Naz A.
Abstract : Bioassay-guided isolation studies on the extracts of yellow flowers of Tagetes patula L. against the Heterodera zeae were carried out to identify phytochemicals lethal to this economically important cyst nematode. In vitro investigation of a polar extract and fractions showing activity led to the isolation of phenolic compounds (flavonoids and phenolic acids). In the nonpolar extract, a few fatty acids, their methyl esters, and thiophenes (including α-terthienyl) were detected. In studies of compounds obtained commercially, α-terthienyl and gallic and linoleic acids showed 100% mortality at concentrations of 0.125% after 24 h. Assessment of structure-activity relationships revealed that an increase in the number of hydroxyl groups in phenolic acids increased the activity; with fatty acids, activity depended on chain length and the number and position of double bonds. Crude extracts of the flowers of different colors also have promising activity.
|
Antioxidant activity assessed as hydroxyl radical scavenging activity at 200 ug/ml
|
None
|
32.0
%
|
|
Journal : Med Chem Res
Title : Lipid lowering and antioxidant activity of flavones in triton treated hyperlipidemic rats
Year : 2011
Volume : 20
Issue : 9
First Page : 1622
Last Page : 1626
Authors : Bhatia G, Khanna AK, Sonkar R, Mishra SK, Srivastava S, Lakshmi V
|
Antioxidant activity assessed as hydroxyl radical scavenging activity at 100 ug/ml
|
None
|
21.0
%
|
|
Journal : Med Chem Res
Title : Lipid lowering and antioxidant activity of flavones in triton treated hyperlipidemic rats
Year : 2011
Volume : 20
Issue : 9
First Page : 1622
Last Page : 1626
Authors : Bhatia G, Khanna AK, Sonkar R, Mishra SK, Srivastava S, Lakshmi V
|
Antihyperlipidemic activity in Rattus norvegicus Charles Foster (rat) trition WR-1339-induced hyperlipidimic model assessed as reduction of total triglyceride level in plasma at 200 mg/kg, po
|
Rattus norvegicus
|
11.0
%
|
|
Journal : Med Chem Res
Title : Lipid lowering and antioxidant activity of flavones in triton treated hyperlipidemic rats
Year : 2011
Volume : 20
Issue : 9
First Page : 1622
Last Page : 1626
Authors : Bhatia G, Khanna AK, Sonkar R, Mishra SK, Srivastava S, Lakshmi V
|
Antihyperlipidemic activity in Rattus norvegicus Charles Foster (rat) trition WR-1339-induced hyperlipidimic model assessed as reduction of total phospholipid level in plasma at 200 mg/kg, po
|
Rattus norvegicus
|
10.0
%
|
|
Journal : Med Chem Res
Title : Lipid lowering and antioxidant activity of flavones in triton treated hyperlipidemic rats
Year : 2011
Volume : 20
Issue : 9
First Page : 1622
Last Page : 1626
Authors : Bhatia G, Khanna AK, Sonkar R, Mishra SK, Srivastava S, Lakshmi V
|
Antihyperlipidemic activity in Rattus norvegicus Charles Foster (rat) trition WR-1339-induced hyperlipidimic model assessed as reduction of total cholesterol level in plasma at 200 mg/kg, po
|
Rattus norvegicus
|
8.0
%
|
|
Journal : Med Chem Res
Title : Lipid lowering and antioxidant activity of flavones in triton treated hyperlipidemic rats
Year : 2011
Volume : 20
Issue : 9
First Page : 1622
Last Page : 1626
Authors : Bhatia G, Khanna AK, Sonkar R, Mishra SK, Srivastava S, Lakshmi V
|
Antifungal activity against Candida albicans PC31 at 0.06 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 0.15 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 0.30 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 0.40 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 0.50 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 0.60 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 1.25 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 1.30 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 1.60 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 1.90 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 2.10 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 2.50 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antifungal activity against Candida albicans PC31 at 2.20 mg/ml after 48 hr
|
Candida albicans
|
None
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
1-octanol-water partition coefficient, log P of the compound
|
None
|
0.31
|
|
Journal : Med Chem Res
Title : Antifungal activity of a novel quercetin derivative bearing a trifluoromethyl group on Candida albicans
Year : 2012
Volume : 21
Issue : 9
First Page : 2217
Last Page : 2222
Authors : Tempesti TC, Alvarez MG, de Araujo MF, Catunda Junior FEA, de Carvalho MG, Durantini EN
|
Antioxidant activity in high cholesterol diet fed Mus musculus KM (mouse) assessed as MDA level in liver at 70 mg/kg, ig for 10 days (Rvb = 9.95 +/- 0.15 nmol/ml)
|
Mus musculus
|
5.1
nmol/ml
|
|
Journal : Med Chem Res
Title : In vitro antioxidant properties and in vivo lowering blood lipid of Forsythia suspense leaves
Year : 2010
Volume : 19
Issue : 7
First Page : 617
Last Page : 628
Authors : Kang W, Wang J
|
Hypolipidemic activity in high cholesterol diet fed Mus musculus KM (mouse) assessed as high density lipoprotein cholesterol at 70 mg/kg, ig for 10 days (Rvb = 1.028 +/- 0.139 mmol/l)
|
Mus musculus
|
1.42
mmol/L
|
|
Journal : Med Chem Res
Title : In vitro antioxidant properties and in vivo lowering blood lipid of Forsythia suspense leaves
Year : 2010
Volume : 19
Issue : 7
First Page : 617
Last Page : 628
Authors : Kang W, Wang J
|
Hypolipidemic activity in high cholesterol diet fed Mus musculus KM (mouse) assessed as low density lipoprotein cholesterol at 70 mg/kg, ig for 10 days (Rvb = 3.386 +/- 0.958 mmol/l)
|
Mus musculus
|
2.64
mmol/L
|
|
Journal : Med Chem Res
Title : In vitro antioxidant properties and in vivo lowering blood lipid of Forsythia suspense leaves
Year : 2010
Volume : 19
Issue : 7
First Page : 617
Last Page : 628
Authors : Kang W, Wang J
|
Hypolipidemic activity in high cholesterol diet fed Mus musculus KM (mouse) assessed as triglyceride level at 70 mg/kg, ig for 10 days (Rvb = 1.391 +/- 0.351 mmol/l)
|
Mus musculus
|
0.828
mmol/L
|
|
Journal : Med Chem Res
Title : In vitro antioxidant properties and in vivo lowering blood lipid of Forsythia suspense leaves
Year : 2010
Volume : 19
Issue : 7
First Page : 617
Last Page : 628
Authors : Kang W, Wang J
|
Hypolipidemic activity in high cholesterol diet fed Mus musculus KM (mouse) assessed as total cholesterol level at 70 mg/kg, ig for 10 days (Rvb = 4.402 +/- 0.8 mmol/l)
|
Mus musculus
|
3.12
mmol/L
|
|
Journal : Med Chem Res
Title : In vitro antioxidant properties and in vivo lowering blood lipid of Forsythia suspense leaves
Year : 2010
Volume : 19
Issue : 7
First Page : 617
Last Page : 628
Authors : Kang W, Wang J
|
Antioxidant activity assessed as ferric ion reducing activity measured as trolox equivalents by FRAP assay
|
None
|
None
|
|
Journal : Med Chem Res
Title : In vitro antioxidant properties and in vivo lowering blood lipid of Forsythia suspense leaves
Year : 2010
Volume : 19
Issue : 7
First Page : 617
Last Page : 628
Authors : Kang W, Wang J
|
Antibacterial activity against Ralstonia solanacearum grown on potato semi-synthetic agar medium at 5 umol/disk by paper disk method
|
Ralstonia solanacearum
|
None
|
|
Journal : J Pesticide Sci
Title : Antibacterial activity of alkyl gallates and related compounds against Ralstonia solanacearum
Year : 2011
Volume : 36
Issue : 2
First Page : 240
Last Page : 242
Authors : Ooshiro A, Kaji M, Katoh Y, Kawaide H, Natsume M
|
Antibacterial activity against Ralstonia solanacearum grown on potato semi-synthetic agar medium at 0.5 umol/disk by paper disk method
|
Ralstonia solanacearum
|
None
|
|
Journal : J Pesticide Sci
Title : Antibacterial activity of alkyl gallates and related compounds against Ralstonia solanacearum
Year : 2011
Volume : 36
Issue : 2
First Page : 240
Last Page : 242
Authors : Ooshiro A, Kaji M, Katoh Y, Kawaide H, Natsume M
|
Anti-inflammatory activity in Mus musculus (mouse) RAW264.7 cells assessed as inhibition of PMA-induced macrophages respiratory burst measured up to 30 min by chemiluminescence method
|
Mus musculus
|
15070.0
nM
|
|
Journal : Med Chem Res
Title : Phenolic and iridoid glycosides from the rhizomes of Cyperus rotundus L.
Year : 2013
Volume : 22
Issue : 10
First Page : 4830
Last Page : 4835
Authors : Zhou Z, Zhang H
|
Non-competitive inhibition of trypsin (unknown origin) using BApNA as substrate by Lineweaver-Burk/Dixon plot analysis
|
Homo sapiens
|
17500.0
nM
|
|
Journal : Med Chem Res
Title : Trypsin inhibitory potential and microbial transformation of rutin isolated from Citrus sinensis
Year : 2013
Volume : 22
Issue : 8
First Page : 3698
Last Page : 3702
Authors : Raza MA, Shahwar D
|
Inhibition of trypsin (unknown origin) using BApNA as substrate incubated for 15 min prior to substrate addition measured after 30 min by UV/VIS spectrophotometric analysis
|
Homo sapiens
|
16000.0
nM
|
|
Journal : Med Chem Res
Title : Trypsin inhibitory potential and microbial transformation of rutin isolated from Citrus sinensis
Year : 2013
Volume : 22
Issue : 8
First Page : 3698
Last Page : 3702
Authors : Raza MA, Shahwar D
|
Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 at 100 ug/ml measured every 24 hr by BACTEC 460 radiometric assay
|
Mycobacterium tuberculosis H37Rv
|
None
|
|
Journal : Med Chem Res
Title : Screening of flavonoids for antitubercular activity and their structureactivity relationships
Year : 2013
Volume : 22
Issue : 6
First Page : 2706
Last Page : 2716
Authors : Yadav AK, Thakur J, Prakash O, Khan F, Saikia D, Gupta MM
