|
Bactericidal activity against Erwinia amylovora 295/93 assessed as growth inhibition applied as spray solution
|
Erwinia amylovora
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 assessed as colony growth inhibition at 25 uM at pH 4.5 by plating assay in presence of 0.5 mg/l mushroom tyrosinase
|
Erwinia amylovora
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Activity of Agaricus bisporus (mushroom) tyrosinase assessed as drug oxidation by photometric analysis
|
Agaricus bisporus
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 assessed as colony growth inhibition at 25 uM at pH 7.2 by plating assay in presence of 0.5 mg/l mushroom tyrosinase
|
Erwinia amylovora
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 assessed as growth inhibition at 10 uM preincubated for 1 hr with visible light by suspension culture assay
|
Erwinia amylovora
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 assessed as growth inhibition at 10 uM preincubated for 1 hr with UV/visible light by suspension culture assay
|
Erwinia amylovora
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against mixture of two strains of Erwinia amylovora 295/93 and 763 inoculated in Malus x domestica cv. Gala flowers assessed as prevention of infection at 0.01 mM applied two times at 2 hr after bacterial exposure measured after 8 to 10 days by In vitro flower inoculation assay
|
Erwinia amylovora
|
67.0
%
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against 2x10'8 CFU/mL Erwinia amylovora 295/93 cells assessed as late restarting of growth from surviving cells at <10 uM by suspension culture assay
|
Erwinia amylovora
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 at 10 uM after 30 min
|
Erwinia amylovora
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Escherichia coli assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Escherichia coli
|
1000000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Pseudomonas fluorescens A506 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Pseudomonas fluorescens A506
|
1000000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Bacillus subtilis NCTC 10315 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Bacillus subtilis
|
50000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Pectobacterium carotovorum NCPB 312 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Pectobacterium carotovorum
|
500000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia piriflorinigrans 5888 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia piriflorinigrans
|
500000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Pantoea agglomerans 599 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Pantoea agglomerans
|
500000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia billingiae 6830 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia billingiae
|
1000000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia tasmaniensis 37/10 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia tasmaniensis
|
500000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia pyrifoliae 4171 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia pyrifoliae
|
20000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 894 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 893 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 872 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
20000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 871 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 846 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
20000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 797 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
20000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 793 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 792 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 782 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 657 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 627 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
20000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 562 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 513 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 385R assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 363 assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
20000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 237R assessed as growth inhibition at pH 7.2 by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 assessed as inhibition of bacterial growth under infection conditions in hrp gene expression inducing medium at pH 7.0 after overnight incubation by suspension culture assay
|
Erwinia amylovora
|
5000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 assessed as growth inhibition at pH 4.5 after overnight incubation by suspension culture assay
|
Erwinia amylovora
|
2500.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 assessed as growth inhibition at 2.5 uM at pH 4.0 to 8.0 by suspension culture assay
|
Erwinia amylovora
|
None
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Bactericidal activity against Erwinia amylovora 295/93 assessed as growth inhibition in King's B full medium measured at pH 7.2 after overnight incubation by suspension culture assay
|
Erwinia amylovora
|
10000.0
nM
|
|
Journal : J Agric Food Chem
Title : Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Year : 2012
Volume : 60
Issue : 49
First Page : 12074
Last Page : 12081
Authors : Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K.
Abstract : A screening of plant quinones for inhibiting effects on the bacterial fire blight pathogen Erwinia amylovora was performed. The most active compound, juglone from walnuts, has a potent and specific bactericidal effect on E. amylovora and minimal inhibitory concentrations of only 2.5-10 μM, with stronger effects at lower, but still physiological, pH values. In vitro tests with juglone and inoculated flowers of apple (Malus domestica) showed an efficacy of 67% in preventing infection. In two years of field tests juglone had variable degrees of efficacy ranging from 40 to 82%, seemingly due to environmental conditions. A phytotoxic reaction to juglone, which is known for its allelopathic effect on plants, was restricted to browning of petals; later fruit russeting was not observed. Juglone is a promising candidate for the development of a new environmentally friendly plant protectant to replace the antibiotic streptomycin currently used in fire blight control.
|
Protection of intact cabbage plants from Trichoplusia ni (cabbage looper) measured as reduction in weight of larvae by lopper in green house for 10 days (Rvb = 33.8 mg)
|
Trichoplusia ni
|
8.1
mg
|
|
Journal : Crop Protection
Title : Antifeedant and toxic effects of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni
Year : 2012
Volume : 31
Issue : 1
First Page : 8
Last Page : 14
Authors : Akhtar Y, Isman MB, Niehaus LA, Lee CH, Lee HS.
Abstract : We investigated the feeding deterrent effects and toxicity of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni. Feeding deterrent effects were determined via a leaf disc choice bioassay. Based on DC₅₀ values, 1,4-naphthoquinone was the most active antifeedant (DC₅₀ = 1.8 μg/cm²) followed by juglone (DC₅₀ = 2.1 μg/cm²), 2-methoxy-1,4-naphthoquinone (DC₅₀ = 2.6 μg/cm²), plumbagin (DC₅₀ = 3.3 μg/cm²), and 2,3-dimethoxy-5-mehtyl-1,4-benzoquinone (DC₅₀ = 4.2 μg/cm²) in third instar cabbage looper larvae. 2-Bromo-1,4-naphthoquinone, 2-chloro-3-morpholino-1,4-naphthoquinone, 1,8-dihydroxy-anthraquinone, 2-methyl-1,4-naphthoquinone and naphthazarin had DC₅₀ values ranging from 8.4 to 10.1 μg/cm². Juglone and plumbagin were able to provide protection to intact cabbage plants in a greenhouse experiment. Cabbage looper larvae consumed less leaf area and weighed less on cabbage plants treated with either of these naturally occurring quinones. Most of the quinones demonstrated levels of antifeedant activity greater than neem, a positive control, in laboratory bioassays. The level of activity for juglone was comparable to neem in the greenhouse experiment. There was also a reduction in the number of larvae on treated plants compared with the negative control. Structure-activity relationships suggest that the antifeedant effects of the tested quinones depend on the number and position of hydroxyl and methoxyl substituents of quinones. Most of the quinones were of medium-low toxicity to third instar cabbage looper larvae via topical administration. Some of these quinones could have potential for development as commercial insect control agents targeting the feeding behavior of insects with minimal toxicity, provided that their impacts on non-target organisms and environment are minimal.
|
Protection of intact cabbage plants from Trichoplusia ni (cabbage looper) measured as leaf area consumed by lopper in green house for 10 days (Rvb = 8.5 cm'2)
|
Trichoplusia ni
|
1.7
cm2
|
|
Journal : Crop Protection
Title : Antifeedant and toxic effects of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni
Year : 2012
Volume : 31
Issue : 1
First Page : 8
Last Page : 14
Authors : Akhtar Y, Isman MB, Niehaus LA, Lee CH, Lee HS.
Abstract : We investigated the feeding deterrent effects and toxicity of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni. Feeding deterrent effects were determined via a leaf disc choice bioassay. Based on DC₅₀ values, 1,4-naphthoquinone was the most active antifeedant (DC₅₀ = 1.8 μg/cm²) followed by juglone (DC₅₀ = 2.1 μg/cm²), 2-methoxy-1,4-naphthoquinone (DC₅₀ = 2.6 μg/cm²), plumbagin (DC₅₀ = 3.3 μg/cm²), and 2,3-dimethoxy-5-mehtyl-1,4-benzoquinone (DC₅₀ = 4.2 μg/cm²) in third instar cabbage looper larvae. 2-Bromo-1,4-naphthoquinone, 2-chloro-3-morpholino-1,4-naphthoquinone, 1,8-dihydroxy-anthraquinone, 2-methyl-1,4-naphthoquinone and naphthazarin had DC₅₀ values ranging from 8.4 to 10.1 μg/cm². Juglone and plumbagin were able to provide protection to intact cabbage plants in a greenhouse experiment. Cabbage looper larvae consumed less leaf area and weighed less on cabbage plants treated with either of these naturally occurring quinones. Most of the quinones demonstrated levels of antifeedant activity greater than neem, a positive control, in laboratory bioassays. The level of activity for juglone was comparable to neem in the greenhouse experiment. There was also a reduction in the number of larvae on treated plants compared with the negative control. Structure-activity relationships suggest that the antifeedant effects of the tested quinones depend on the number and position of hydroxyl and methoxyl substituents of quinones. Most of the quinones were of medium-low toxicity to third instar cabbage looper larvae via topical administration. Some of these quinones could have potential for development as commercial insect control agents targeting the feeding behavior of insects with minimal toxicity, provided that their impacts on non-target organisms and environment are minimal.
|
Toxicity against Trichoplusia ni (cabbage looper) third-instar larvae stage assessed as mortality at 10 ug/ml for 24 hr by topical application
|
Trichoplusia ni
|
5.0
%
|
|
Journal : Crop Protection
Title : Antifeedant and toxic effects of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni
Year : 2012
Volume : 31
Issue : 1
First Page : 8
Last Page : 14
Authors : Akhtar Y, Isman MB, Niehaus LA, Lee CH, Lee HS.
Abstract : We investigated the feeding deterrent effects and toxicity of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni. Feeding deterrent effects were determined via a leaf disc choice bioassay. Based on DC₅₀ values, 1,4-naphthoquinone was the most active antifeedant (DC₅₀ = 1.8 μg/cm²) followed by juglone (DC₅₀ = 2.1 μg/cm²), 2-methoxy-1,4-naphthoquinone (DC₅₀ = 2.6 μg/cm²), plumbagin (DC₅₀ = 3.3 μg/cm²), and 2,3-dimethoxy-5-mehtyl-1,4-benzoquinone (DC₅₀ = 4.2 μg/cm²) in third instar cabbage looper larvae. 2-Bromo-1,4-naphthoquinone, 2-chloro-3-morpholino-1,4-naphthoquinone, 1,8-dihydroxy-anthraquinone, 2-methyl-1,4-naphthoquinone and naphthazarin had DC₅₀ values ranging from 8.4 to 10.1 μg/cm². Juglone and plumbagin were able to provide protection to intact cabbage plants in a greenhouse experiment. Cabbage looper larvae consumed less leaf area and weighed less on cabbage plants treated with either of these naturally occurring quinones. Most of the quinones demonstrated levels of antifeedant activity greater than neem, a positive control, in laboratory bioassays. The level of activity for juglone was comparable to neem in the greenhouse experiment. There was also a reduction in the number of larvae on treated plants compared with the negative control. Structure-activity relationships suggest that the antifeedant effects of the tested quinones depend on the number and position of hydroxyl and methoxyl substituents of quinones. Most of the quinones were of medium-low toxicity to third instar cabbage looper larvae via topical administration. Some of these quinones could have potential for development as commercial insect control agents targeting the feeding behavior of insects with minimal toxicity, provided that their impacts on non-target organisms and environment are minimal.
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Antifeedant activity against Trichoplusia ni (cabbage looper) third-instar larvae stage assessed as concentrations causing 50% feeding deterrence by feeding deterrent bioassay
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Trichoplusia ni
|
2.1
microg/cm2
|
|
Journal : Crop Protection
Title : Antifeedant and toxic effects of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni
Year : 2012
Volume : 31
Issue : 1
First Page : 8
Last Page : 14
Authors : Akhtar Y, Isman MB, Niehaus LA, Lee CH, Lee HS.
Abstract : We investigated the feeding deterrent effects and toxicity of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni. Feeding deterrent effects were determined via a leaf disc choice bioassay. Based on DC₅₀ values, 1,4-naphthoquinone was the most active antifeedant (DC₅₀ = 1.8 μg/cm²) followed by juglone (DC₅₀ = 2.1 μg/cm²), 2-methoxy-1,4-naphthoquinone (DC₅₀ = 2.6 μg/cm²), plumbagin (DC₅₀ = 3.3 μg/cm²), and 2,3-dimethoxy-5-mehtyl-1,4-benzoquinone (DC₅₀ = 4.2 μg/cm²) in third instar cabbage looper larvae. 2-Bromo-1,4-naphthoquinone, 2-chloro-3-morpholino-1,4-naphthoquinone, 1,8-dihydroxy-anthraquinone, 2-methyl-1,4-naphthoquinone and naphthazarin had DC₅₀ values ranging from 8.4 to 10.1 μg/cm². Juglone and plumbagin were able to provide protection to intact cabbage plants in a greenhouse experiment. Cabbage looper larvae consumed less leaf area and weighed less on cabbage plants treated with either of these naturally occurring quinones. Most of the quinones demonstrated levels of antifeedant activity greater than neem, a positive control, in laboratory bioassays. The level of activity for juglone was comparable to neem in the greenhouse experiment. There was also a reduction in the number of larvae on treated plants compared with the negative control. Structure-activity relationships suggest that the antifeedant effects of the tested quinones depend on the number and position of hydroxyl and methoxyl substituents of quinones. Most of the quinones were of medium-low toxicity to third instar cabbage looper larvae via topical administration. Some of these quinones could have potential for development as commercial insect control agents targeting the feeding behavior of insects with minimal toxicity, provided that their impacts on non-target organisms and environment are minimal.
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Antifeedant activity against Trichoplusia ni (cabbage looper) third-instar larvae stage assessed as feeding deterrence index at 50 microg/cm'2 by feeding deterrent bioassay
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Trichoplusia ni
|
100.0
%
|
|
Journal : Crop Protection
Title : Antifeedant and toxic effects of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni
Year : 2012
Volume : 31
Issue : 1
First Page : 8
Last Page : 14
Authors : Akhtar Y, Isman MB, Niehaus LA, Lee CH, Lee HS.
Abstract : We investigated the feeding deterrent effects and toxicity of naturally occurring and synthetic quinones to the cabbage looper, Trichoplusia ni. Feeding deterrent effects were determined via a leaf disc choice bioassay. Based on DC₅₀ values, 1,4-naphthoquinone was the most active antifeedant (DC₅₀ = 1.8 μg/cm²) followed by juglone (DC₅₀ = 2.1 μg/cm²), 2-methoxy-1,4-naphthoquinone (DC₅₀ = 2.6 μg/cm²), plumbagin (DC₅₀ = 3.3 μg/cm²), and 2,3-dimethoxy-5-mehtyl-1,4-benzoquinone (DC₅₀ = 4.2 μg/cm²) in third instar cabbage looper larvae. 2-Bromo-1,4-naphthoquinone, 2-chloro-3-morpholino-1,4-naphthoquinone, 1,8-dihydroxy-anthraquinone, 2-methyl-1,4-naphthoquinone and naphthazarin had DC₅₀ values ranging from 8.4 to 10.1 μg/cm². Juglone and plumbagin were able to provide protection to intact cabbage plants in a greenhouse experiment. Cabbage looper larvae consumed less leaf area and weighed less on cabbage plants treated with either of these naturally occurring quinones. Most of the quinones demonstrated levels of antifeedant activity greater than neem, a positive control, in laboratory bioassays. The level of activity for juglone was comparable to neem in the greenhouse experiment. There was also a reduction in the number of larvae on treated plants compared with the negative control. Structure-activity relationships suggest that the antifeedant effects of the tested quinones depend on the number and position of hydroxyl and methoxyl substituents of quinones. Most of the quinones were of medium-low toxicity to third instar cabbage looper larvae via topical administration. Some of these quinones could have potential for development as commercial insect control agents targeting the feeding behavior of insects with minimal toxicity, provided that their impacts on non-target organisms and environment are minimal.
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Antitubercular activity against Mycobacterium tuberculosis H37Rv by BACTEC method
|
Mycobacterium tuberculosis H37Rv
|
833489244.53
nM
|
|
Antitubercular activity against Mycobacterium tuberculosis H37Rv by BACTEC method
|
Mycobacterium tuberculosis H37Rv
|
1.2
nM
|
|
Journal : Med Chem Res
Year : 2012
Volume : 21
Issue : 8
First Page : 2006
Last Page : 2011
