BORIC ACID


Synonyms	Boric Acid E284
UNII	R57ZHV85D4
Source	Gaulton A, Kale N, van Westen GJ, Bellis LJ, Bento AP, Davies M, Hersey A, Papadatos G, Forster M, Wege P, Overington JP. A large-scale crop protection bioassay data set. Sci Data. 2015 Jul 7;2:150032. Read more ...


Active Pharmaceutical Ingredients Bioactive chemicals	Exact Similarity SubStructure	Threshold (%) >= 70

Structure


InChI Key	KGBXLFKZBHKPEV-UHFFFAOYSA-N
Smiles	OB(O)O
InChI	InChI=1S/BH3O3/c2-1(3)4/h2-4H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	BH3O3
Molecular Weight	61.83
AlogP	None
Hydrogen Bond Acceptor	None
Hydrogen Bond Donor	None
Number of Rotational Bond	None
Polar Surface Area	None
Molecular species	None
Aromatic Rings	None
Heavy Atoms	None

Reference

Journal : Crop Protection

Title : Seed and leaf treatments with natural compounds to induce resistance against Peronospora parasitica in Brassica oleracea

DOI : 10.1016/j.cropro.2012.01.008

Year : 2012

Volume : 35

First Page : 78

Last Page : 84

Authors : van der Wolf JM, Michta A, van der Zouwen PS, de Boer WJ, Davelaar E, Stevens LH.

Abstract : Seed and leaf treatments with natural compounds having a low risk profile (LRP) were evaluated for their potential to induce resistance in cabbage plants (Brassica oleracea) against Peronospora parasitica, causal organism of downy mildew. The selection of 34 LRP compounds comprised micronutrients, organic compounds such as proline, riboflavin, oligogalacturonides, aminolignosulfonates, bacterial lipopolysaccharides, and bacterial and fungal extracts. Treatments with the synthetic chemical inducers 2,6-dichloroisonicotinic acid (INA), d,l-β-aminobutyric acid, salicylic acid, benzothiadiazole and the fungicide Previcur™ were included as controls. After seed treatment a maximum reduction of 27% diseased leaf area was found with an extract of a Lysobacter strain, compared to a reduction of 99% for INA, the most effective synthetic inducer. Seed treatments with extracts of Pectobacterium carotovorum subsp. carotovorum, Bacillus macerans, Pseudomonas syringae, Streptomyces and Xanthomonas campestris strains also reduced downy mildew infection significantly. After leaf treatment, a maximum reduction of 85% was again found with the Lysobacter extract, compared to a reduction of 99% for INA, the most effective synthetic inducer. Leaf treatments with CuSO4 (≥1 mM), MnCl2 (≥10 mM), K2HPO4 (100 mM), and extracts of P. syringae, P. carotovorum subsp. carotovorum, Streptomyces, X. campestris and B. macerans strains also reduced the diseased leaf area, but CuSO4 was highly phytotoxic. For seed and leaf treatments with Lysobacter extract, proline, MnCl2 and INA the effect on the induction of chitinase and glucanase activity was tested, using two pathogenesis-related proteins as markers for induced resistance. For seed treatments only INA and for leaf treatments INA, proline and MnCl2 treatments resulted in increased activity of both enzymes. The rate of enzyme activity induced by INA was dependent on the time seeds were exposed to the compound.

Reference

Journal : Crop Protection

Title : Seed and leaf treatments with natural compounds to induce resistance against Peronospora parasitica in Brassica oleracea

DOI : 10.1016/j.cropro.2012.01.008

Year : 2012

Volume : 35

First Page : 78

Last Page : 84

Authors : van der Wolf JM, Michta A, van der Zouwen PS, de Boer WJ, Davelaar E, Stevens LH.

Reference

Journal : Crop Protection

Title : Seed and leaf treatments with natural compounds to induce resistance against Peronospora parasitica in Brassica oleracea

DOI : 10.1016/j.cropro.2012.01.008

Year : 2012

Volume : 35

First Page : 78

Last Page : 84

Authors : van der Wolf JM, Michta A, van der Zouwen PS, de Boer WJ, Davelaar E, Stevens LH.

Assay Description	Organism	Bioactivity
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 20 mM sprayed on leaves of one week old seedlings relative to untreated control	Hyaloperonospora parasitica	77.0 %
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 10 mM sprayed on leaves of one week old seedlings relative to untreated control	Hyaloperonospora parasitica	71.0 %
Induction of systemic acquired resistance against Hyaloperonospora parasitica-induced downy mildew disease in white cabbage assessed as infected leaf area at 5 mM sprayed on leaves of one week old seedlings relative to untreated control	Hyaloperonospora parasitica	96.4 %

Cross References

Resources	Reference
ChEMBL	CHEMBL42403
FDA SRS	R57ZHV85D4
PDB	BO3
PubChem	7628
SureChEMBL	SCHEMBL3736

CONTENTS

Structure
Chemical and Physical Properties