|
Antifungal activity against Diplodia seriata BoF98-1 assessed as growth inhibition measured after 1 to 10 days
|
Diplodia seriata
|
24.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Diplodia seriata BoF99-1 assessed as growth inhibition measured after 1 to 10 days
|
Diplodia seriata
|
24.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Diplodia seriata LAT28 assessed as growth inhibition measured after 1 to 10 days
|
Diplodia seriata
|
24.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Lasiodiplodia theobromae CBS116460 assessed as growth inhibition measured after 1 to 10 days
|
Lasiodiplodia theobromae
|
24.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Diplodia seriata PLU03 assessed as growth inhibition measured after 1 to 10 days
|
Diplodia seriata
|
24.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Diplodia mutila BRA08 assessed as growth inhibition measured after 1 to 10 days
|
Diplodia mutila
|
24.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Neofusicoccum luteum CBS110299 assessed as growth inhibition measured after 1 to 10 days
|
Neofusicoccum luteum
|
14.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Neofusicoccum parvum PER20 assessed as growth inhibition measured after 1 to 10 days
|
Neofusicoccum parvum
|
14.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Neofusicoccum parvum Bp0014 assessed as growth inhibition measured after 1 to 10 days
|
Neofusicoccum parvum
|
14.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Botryosphaeria dothidea OGE14 assessed as growth inhibition measured after 1 to 10 days relative to control
|
Botryosphaeria dothidea
|
14.0
%
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Eutypa lata BX1-10 assessed as growth inhibition at 500 uM measured after 1 to 10 days relative to control
|
Eutypa lata
|
None
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Antifungal activity against Togninia minima SO21 assessed as susceptibility at 500 uM measured after 1 to 10 days
|
Togninia minima
|
None
|
|
Journal : J Agric Food Chem
Title : Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
Year : 2012
Volume : 60
Issue : 48
First Page : 11859
Last Page : 11868
Authors : Lambert C, Bisson J, Waffo-Téguo P, Papastamoulis Y, Richard T, Corio-Costet MF, Mérillon JM, Cluzet S.
Abstract : The interaction between Vitis vinifera and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
|
Stimulation of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 30 mg/mL
|
Cydia pomonella
|
None
|
|
Journal : J Agric Food Chem
Title : Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
Year : 2011
Volume : 59
Issue : 20
First Page : 10879
Last Page : 10886
Authors : Pszczolkowski MA, Durden K, Sellars S, Cowell B, Brown JJ.
Abstract : Codling moth, Cydia pomonella (L.), is a cosmopolitan pest of apple, potentially causing severe damage to the fruit. Currently used methods of combating this insect do not warrant full success or are harmful to the environment. The use of plant-derived semiochemicals for manipulation with fruit-infesting behavior is one of the new avenues for controlling this pest. Here, we explore the potential of Ginkgo biloba and its synthetic metabolites for preventing apple feeding and infestation by neonate larvae of C. pomonella. Experiments with crude extracts indicated that deterrent constituents of ginkgo are present among alkylphenols, terpene trilactones, and flavonol glycosides. Further experiments with ginkgo synthetic metabolites of medical importance, ginkgolic acids, kaempferol, quercetin, isorhamnetin, ginkgolides, and bilobalide, indicated that three out of these chemicals have feeding deterrent properties. Ginkgolic acid 15:0 prevented fruit infestation at concentrations as low as 1 mg/mL, bilobalide had deterrent effects at 0.1 mg/mL and higher concentrations, and ginkgolide B at 10 mg/mL. On the other hand, kaempferol and quercetin promoted fruit infestation by codling moth neonates. Ginkgolic acids 13:0, 15:1, and 17:1, isorhamnetin, and ginkgolides A and C had no effects on fruit infestation-related behavior. Our research is the first report showing that ginkgo constituents influence fruit infestation behavior and have potential applications in fruit protection.
|
Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 30 mg/mL
|
Cydia pomonella
|
None
|
|
Journal : J Agric Food Chem
Title : Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
Year : 2011
Volume : 59
Issue : 20
First Page : 10879
Last Page : 10886
Authors : Pszczolkowski MA, Durden K, Sellars S, Cowell B, Brown JJ.
Abstract : Codling moth, Cydia pomonella (L.), is a cosmopolitan pest of apple, potentially causing severe damage to the fruit. Currently used methods of combating this insect do not warrant full success or are harmful to the environment. The use of plant-derived semiochemicals for manipulation with fruit-infesting behavior is one of the new avenues for controlling this pest. Here, we explore the potential of Ginkgo biloba and its synthetic metabolites for preventing apple feeding and infestation by neonate larvae of C. pomonella. Experiments with crude extracts indicated that deterrent constituents of ginkgo are present among alkylphenols, terpene trilactones, and flavonol glycosides. Further experiments with ginkgo synthetic metabolites of medical importance, ginkgolic acids, kaempferol, quercetin, isorhamnetin, ginkgolides, and bilobalide, indicated that three out of these chemicals have feeding deterrent properties. Ginkgolic acid 15:0 prevented fruit infestation at concentrations as low as 1 mg/mL, bilobalide had deterrent effects at 0.1 mg/mL and higher concentrations, and ginkgolide B at 10 mg/mL. On the other hand, kaempferol and quercetin promoted fruit infestation by codling moth neonates. Ginkgolic acids 13:0, 15:1, and 17:1, isorhamnetin, and ginkgolides A and C had no effects on fruit infestation-related behavior. Our research is the first report showing that ginkgo constituents influence fruit infestation behavior and have potential applications in fruit protection.
|
Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 60 mg/mL
|
Cydia pomonella
|
None
|
|
Journal : J Agric Food Chem
Title : Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
Year : 2011
Volume : 59
Issue : 20
First Page : 10879
Last Page : 10886
Authors : Pszczolkowski MA, Durden K, Sellars S, Cowell B, Brown JJ.
Abstract : Codling moth, Cydia pomonella (L.), is a cosmopolitan pest of apple, potentially causing severe damage to the fruit. Currently used methods of combating this insect do not warrant full success or are harmful to the environment. The use of plant-derived semiochemicals for manipulation with fruit-infesting behavior is one of the new avenues for controlling this pest. Here, we explore the potential of Ginkgo biloba and its synthetic metabolites for preventing apple feeding and infestation by neonate larvae of C. pomonella. Experiments with crude extracts indicated that deterrent constituents of ginkgo are present among alkylphenols, terpene trilactones, and flavonol glycosides. Further experiments with ginkgo synthetic metabolites of medical importance, ginkgolic acids, kaempferol, quercetin, isorhamnetin, ginkgolides, and bilobalide, indicated that three out of these chemicals have feeding deterrent properties. Ginkgolic acid 15:0 prevented fruit infestation at concentrations as low as 1 mg/mL, bilobalide had deterrent effects at 0.1 mg/mL and higher concentrations, and ginkgolide B at 10 mg/mL. On the other hand, kaempferol and quercetin promoted fruit infestation by codling moth neonates. Ginkgolic acids 13:0, 15:1, and 17:1, isorhamnetin, and ginkgolides A and C had no effects on fruit infestation-related behavior. Our research is the first report showing that ginkgo constituents influence fruit infestation behavior and have potential applications in fruit protection.
|
Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 0.1 mg/mL
|
Cydia pomonella
|
None
|
|
Journal : J Agric Food Chem
Title : Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
Year : 2011
Volume : 59
Issue : 20
First Page : 10879
Last Page : 10886
Authors : Pszczolkowski MA, Durden K, Sellars S, Cowell B, Brown JJ.
Abstract : Codling moth, Cydia pomonella (L.), is a cosmopolitan pest of apple, potentially causing severe damage to the fruit. Currently used methods of combating this insect do not warrant full success or are harmful to the environment. The use of plant-derived semiochemicals for manipulation with fruit-infesting behavior is one of the new avenues for controlling this pest. Here, we explore the potential of Ginkgo biloba and its synthetic metabolites for preventing apple feeding and infestation by neonate larvae of C. pomonella. Experiments with crude extracts indicated that deterrent constituents of ginkgo are present among alkylphenols, terpene trilactones, and flavonol glycosides. Further experiments with ginkgo synthetic metabolites of medical importance, ginkgolic acids, kaempferol, quercetin, isorhamnetin, ginkgolides, and bilobalide, indicated that three out of these chemicals have feeding deterrent properties. Ginkgolic acid 15:0 prevented fruit infestation at concentrations as low as 1 mg/mL, bilobalide had deterrent effects at 0.1 mg/mL and higher concentrations, and ginkgolide B at 10 mg/mL. On the other hand, kaempferol and quercetin promoted fruit infestation by codling moth neonates. Ginkgolic acids 13:0, 15:1, and 17:1, isorhamnetin, and ginkgolides A and C had no effects on fruit infestation-related behavior. Our research is the first report showing that ginkgo constituents influence fruit infestation behavior and have potential applications in fruit protection.
|
Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 1 mg/mL
|
Cydia pomonella
|
25.0
%
|
|
Journal : J Agric Food Chem
Title : Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
Year : 2011
Volume : 59
Issue : 20
First Page : 10879
Last Page : 10886
Authors : Pszczolkowski MA, Durden K, Sellars S, Cowell B, Brown JJ.
Abstract : Codling moth, Cydia pomonella (L.), is a cosmopolitan pest of apple, potentially causing severe damage to the fruit. Currently used methods of combating this insect do not warrant full success or are harmful to the environment. The use of plant-derived semiochemicals for manipulation with fruit-infesting behavior is one of the new avenues for controlling this pest. Here, we explore the potential of Ginkgo biloba and its synthetic metabolites for preventing apple feeding and infestation by neonate larvae of C. pomonella. Experiments with crude extracts indicated that deterrent constituents of ginkgo are present among alkylphenols, terpene trilactones, and flavonol glycosides. Further experiments with ginkgo synthetic metabolites of medical importance, ginkgolic acids, kaempferol, quercetin, isorhamnetin, ginkgolides, and bilobalide, indicated that three out of these chemicals have feeding deterrent properties. Ginkgolic acid 15:0 prevented fruit infestation at concentrations as low as 1 mg/mL, bilobalide had deterrent effects at 0.1 mg/mL and higher concentrations, and ginkgolide B at 10 mg/mL. On the other hand, kaempferol and quercetin promoted fruit infestation by codling moth neonates. Ginkgolic acids 13:0, 15:1, and 17:1, isorhamnetin, and ginkgolides A and C had no effects on fruit infestation-related behavior. Our research is the first report showing that ginkgo constituents influence fruit infestation behavior and have potential applications in fruit protection.
|
Inhibition of fruit-infesting behavior of Cydia pomonella (codling moth) neonates infested in apple fruit plugs assessed as feeding deterrence index at 10 mg/mL
|
Cydia pomonella
|
None
|
|
Journal : J Agric Food Chem
Title : Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
Year : 2011
Volume : 59
Issue : 20
First Page : 10879
Last Page : 10886
Authors : Pszczolkowski MA, Durden K, Sellars S, Cowell B, Brown JJ.
Abstract : Codling moth, Cydia pomonella (L.), is a cosmopolitan pest of apple, potentially causing severe damage to the fruit. Currently used methods of combating this insect do not warrant full success or are harmful to the environment. The use of plant-derived semiochemicals for manipulation with fruit-infesting behavior is one of the new avenues for controlling this pest. Here, we explore the potential of Ginkgo biloba and its synthetic metabolites for preventing apple feeding and infestation by neonate larvae of C. pomonella. Experiments with crude extracts indicated that deterrent constituents of ginkgo are present among alkylphenols, terpene trilactones, and flavonol glycosides. Further experiments with ginkgo synthetic metabolites of medical importance, ginkgolic acids, kaempferol, quercetin, isorhamnetin, ginkgolides, and bilobalide, indicated that three out of these chemicals have feeding deterrent properties. Ginkgolic acid 15:0 prevented fruit infestation at concentrations as low as 1 mg/mL, bilobalide had deterrent effects at 0.1 mg/mL and higher concentrations, and ginkgolide B at 10 mg/mL. On the other hand, kaempferol and quercetin promoted fruit infestation by codling moth neonates. Ginkgolic acids 13:0, 15:1, and 17:1, isorhamnetin, and ginkgolides A and C had no effects on fruit infestation-related behavior. Our research is the first report showing that ginkgo constituents influence fruit infestation behavior and have potential applications in fruit protection.
|
Inhibition of Avian myeloblastosis virus reverse transcriptase
|
Avian myeloblastosis virus
|
72.6
%
|
|
Journal : Med Chem Res
Title : 3D-QSAR studies of natural flavonoid compounds as reverse transcriptase inhibitors
Year : 2012
Volume : 21
Issue : 5
First Page : 559
Last Page : 567
Authors : Phosrithong N, Samee W, Ungwitayatorn J
|
Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by spectrophotometry
|
Saccharomyces cerevisiae
|
1.08
|
|
Journal : Med Chem Res
Title : Two-dimensional quantitative structureactivity relationship study on polyphenols as inhibitors of -glucosidase
Year : 2012
Volume : 21
Issue : 12
First Page : 3984
Last Page : 3993
Authors : Rastija V, Beslo D, Nikolic S
|
Inhibition of Homo sapiens (human) cyclin-dependent kinase 6
|
Homo sapiens
|
22000.0
nM
|
|
Journal : Med Chem Res
Title : Molecular docking study on anticancer activity of plant-derived natural products
Year : 2010
Volume : 19
Issue : 8
First Page : 817
Last Page : 835
Authors : Phosrithong N, Ungwitayatorn J
|
Antioxidant activity assessed as inhibition of DPPH radical production after 30 min by spectrophotometric analysis
|
None
|
2.51
ug.mL-1
|
|
Journal : Med Chem Res
Title : Antioxidant phenolic compounds and flavonoids of Mitragyna rotundifolia (Roxb.) Kuntze in vitro
Year : 2010
Volume : 19
Issue : 9
First Page : 1222
Last Page : 1232
Authors : Kang W, Li C, Liu Y
|
Antioxidant activity assessed as inhibition of ABTS radical production after 10 min by spectrophotometric analysis
|
None
|
1.03
ug.mL-1
|
|
Journal : Med Chem Res
Title : Antioxidant phenolic compounds and flavonoids of Mitragyna rotundifolia (Roxb.) Kuntze in vitro
Year : 2010
Volume : 19
Issue : 9
First Page : 1222
Last Page : 1232
Authors : Kang W, Li C, Liu Y
|
Antioxidant activity assessed as inhibition of DPPH radical production after 30 min by microplate assay
|
None
|
14.78
ug.mL-1
|
|
Journal : Med Chem Res
Title : -Glucosidase inhibitory and antioxidant properties and antidiabetic activity of Hypericum ascyron L.
Year : 2011
Volume : 20
Issue : 7
First Page : 809
Last Page : 816
Authors : Kang W, Song Y, Zhang L
|
Antioxidant activity assessed as inhibition of DPPH radical production at 54.05 ug/ml after 30 min by microplate assay
|
None
|
90.1
%
|
|
Journal : Med Chem Res
Title : -Glucosidase inhibitory and antioxidant properties and antidiabetic activity of Hypericum ascyron L.
Year : 2011
Volume : 20
Issue : 7
First Page : 809
Last Page : 816
Authors : Kang W, Song Y, Zhang L
|
Inhibition ofRattus norvegicus alpha-glucosidase isolated from intestine using PNPG as substrate incubated for 15 min prior to substrate addition measured after 15 min by spectrophotometric analysis
|
Rattus norvegicus
|
59540.0
nM
|
|
Journal : Med Chem Res
Title : -Glucosidase inhibitory and antioxidant properties and antidiabetic activity of Hypericum ascyron L.
Year : 2011
Volume : 20
Issue : 7
First Page : 809
Last Page : 816
Authors : Kang W, Song Y, Zhang L
|
Inhibition ofRattus norvegicus alpha-glucosidase isolated from intestine using PNPG as substrate at 0.03 uM incubated for 15 min prior to substrate addition measured after 15 min by spectrophotometric analysis
|
Rattus norvegicus
|
99.34
%
|
|
Journal : Med Chem Res
Title : -Glucosidase inhibitory and antioxidant properties and antidiabetic activity of Hypericum ascyron L.
Year : 2011
Volume : 20
Issue : 7
First Page : 809
Last Page : 816
Authors : Kang W, Song Y, Zhang L
|
Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate incubated for 15 min prior to substrate addition measured after 15 min by spectrophotometric analysis
|
Homo sapiens
|
61830.0
nM
|
|
Journal : Med Chem Res
Title : -Glucosidase inhibitory and antioxidant properties and antidiabetic activity of Hypericum ascyron L.
Year : 2011
Volume : 20
Issue : 7
First Page : 809
Last Page : 816
Authors : Kang W, Song Y, Zhang L
|
Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate at 0.03 uM incubated for 15 min prior to substrate addition measured after 15 min by spectrophotometric analysis
|
Homo sapiens
|
51.47
%
|
|
Journal : Med Chem Res
Title : -Glucosidase inhibitory and antioxidant properties and antidiabetic activity of Hypericum ascyron L.
Year : 2011
Volume : 20
Issue : 7
First Page : 809
Last Page : 816
Authors : Kang W, Song Y, Zhang L
|
Antioxidant activity assessed as inhibition of DPPH radical production at 33 uM after 5 min by spectrophotometric analysis
|
None
|
93.5
%
|
|
Journal : Med Chem Res
Title : Quantum chemical QSAR study of flavones and their radical-scavenging activity
Year : 2007
Volume : 16
Issue : 7
First Page : 408
Last Page : 417
Authors : Pasha FA, Cho SJ, Beg Y, Tripathi YB
|
Antiamoebic activity against Entamoeba histolytica
|
Entamoeba histolytica
|
7.93
ug.mL-1
|
|
Journal : Med Chem Res
Title : Exploring QSAR of antiamoebic agents of isolated natural products by MLR, ANN, and RTO
Year : 2012
Volume : 21
Issue : 9
First Page : 2501
Last Page : 2516
Authors : Ramirez-Galicia G, Martinez-Pacheco H, Garduno-Juarez R, Deeb O
|
Phytotoxicity in Solanum lycopersicum (tomato) assessed as inhibition of seed germination at 250 ug/mL measured on day 14 relative to untreated control
|
Solanum lycopersicum
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Triticum aestivum (wheat) assessed as inhibition of seed germination at 250 ug/mL measured on day 14 relative to untreated control
|
Triticum aestivum
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Linaria genistifolia subsp. dalmatica assessed as inhibition of seed germination at 250 ug/mL measured on day 14 relative to untreated control
|
Linaria genistifolia subsp. dalmatica
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Centaurea diffusa assessed as inhibition of seed germination at 250 ug/mL measured on day 14 relative to untreated control
|
Centaurea diffusa
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Arabidopsis thaliana assessed as inhibition of seed germination at 250 ug/mL measured on day 14 relative to untreated control
|
Arabidopsis thaliana
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Bassia scoparia assessed as inhibition of seed germination at 250 ug/mL measured on day 14 relative to untreated control
|
Bassia scoparia
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Centaurea maculosa assessed as inhibition of seed germination at 250 ug/mL measured on day 14 relative to untreated control
|
Centaurea maculosa
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Solanum lycopersicum (tomato) assessed as increase in mortality at 250 ug/mL measured on day 14 relative to untreated control
|
Solanum lycopersicum
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Triticum aestivum (wheat) assessed as increase in mortality at 250 ug/mL measured on day 14 relative to untreated control
|
Triticum aestivum
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Arabidopsis thaliana assessed as increase in mortality at 250 ug/mL measured on day 14 relative to untreated control
|
Arabidopsis thaliana
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Bassia scoparia assessed as increase in mortality at 250 ug/mL measured on day 14 relative to untreated control
|
Bassia scoparia
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Linaria genistifolia subsp. dalmatica assessed as increase in mortality at 250 ug/mL measured on day 14 relative to untreated control
|
Linaria genistifolia subsp. dalmatica
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Centaurea diffusa assessed as increase in mortality at 250 ug/mL measured on day 14 relative to untreated control
|
Centaurea diffusa
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
Phytotoxicity in Centaurea maculosa assessed as increase in mortality at 250 ug/mL measured on day 14 relative to untreated control
|
Centaurea maculosa
|
None
|
|
Journal : J Agric Food Chem
Title : Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Year : 2003
Volume : 51
Issue : 4
First Page : 897
Last Page : 901
Authors : Bais HP, Walker TS, Kennan AJ, Stermitz FR, Vivanco JM.
Abstract : Invasive plants are believed to succeed in part by secretion of allelochemicals, thus displacing competing plant species. Centaurea maculosa (spotted knapweed) provides a classic example of this process. We have previously reported that spotted knapweed roots secrete (+/-)-catechin and that (-)-catechin, but not (+)-catechin, is phytotoxic and hence may be a major contributor to C. maculosa's invasive behavior in the rhizosphere. In this communication, we explore both structure/activity relationships for flavonoid phytotoxicity and possible biosynthetic pathways for root production of (+/-)-catechin. Kaempferol and dihydroquercetin were shown to be phytotoxic, while quercetin was not. Kaempferol was converted to dihydroquercetin and (+/-)-catechin when treated with total root protein extracts from C. maculosa, but quercetin was not. This finding suggests an alteration in the standard flavonoid biosynthetic pathway in C. maculosa roots, whereby kaempferol is not a dead-end product but serves as a precursor to dihydroquercetin, which in turn leads to (+/-)-catechin production.
|
inhibition of Influenza A virus H3N2 neuraminidase
|
Influenza A virus H3N2
|
38100.0
nM
|
|
Journal : Med Chem Res
Title : Discovery of a series of novel compounds with moderate anti-avian H5N1 influenza virus activity in chick embryo
Year : 2013
Volume : 22
Issue : 7
First Page : 3485
Last Page : 3496
Authors : Xie Y, Huang B, Yu K, Shi F, Xu W
|
Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 at 100 ug/ml measured every 24 hr by BACTEC 460 radiometric assay
|
Mycobacterium tuberculosis H37Rv
|
None
|
|
Journal : Med Chem Res
Title : Screening of flavonoids for antitubercular activity and their structureactivity relationships
Year : 2013
Volume : 22
Issue : 6
First Page : 2706
Last Page : 2716
Authors : Yadav AK, Thakur J, Prakash O, Khan F, Saikia D, Gupta MM
|
Inhibition of NADPH oxidase in Homo sapiens (human) HUVEC cells
|
Homo sapiens
|
10000.0
nM
|
|
Journal : Med Chem Res
Title : Flavonoids as lead compounds modulating the enzyme targets in Alzheimers disease
Year : 2013
Volume : 22
Issue : 7
First Page : 3061
Last Page : 3075
Authors : Anand P, Singh B
|
Inhibition of BACE1 (unknown origin)
|
Homo sapiens
|
14700.0
nM
|
|
Journal : Med Chem Res
Title : Flavonoids as lead compounds modulating the enzyme targets in Alzheimers disease
Year : 2013
Volume : 22
Issue : 7
First Page : 3061
Last Page : 3075
Authors : Anand P, Singh B
