|
Growth inhibitory activity against po dosed fourth-instar larvae of Spodoptera frugiperda (fall armyworm) assessed as proportion of prothetely appearance of precocious pupal structure in larvae after 48 to 72 hr
|
Spodoptera frugiperda
|
30.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against po dosed Spodoptera frugiperda (fall armyworm) larvae assessed as promotion of apolysis to fifth instar with ecdysis inhibition at 5 to 20 ug/ml
|
Spodoptera frugiperda
|
None
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against Drosophila melanogaster larvae fed with compound incorporated diet assessed as mortality after 72 hr by not choice test
|
Drosophila melanogaster
|
16.1
ug.mL-1
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as relative growth index at 50 ug/ml (Rvb = 1.0 no_unit)
|
Spodoptera frugiperda
|
0.71
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as relative growth index at 35 ug/ml (Rvb = 1.0 no_unit)
|
Spodoptera frugiperda
|
0.75
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as relative growth index at 20 ug/ml (Rvb = 1.0 no_unit)
|
Spodoptera frugiperda
|
0.96
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as relative growth index at 10 ug/ml (Rvb = 1.0 no_unit)
|
Spodoptera frugiperda
|
0.98
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as relative growth index at 5 ug/ml (Rvb = 1.0 no_unit)
|
Spodoptera frugiperda
|
0.99
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as growth index at 50 ug/ml (Rvb = 0.95 +/-0.02 no_unit)
|
Spodoptera frugiperda
|
0.54
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as growth index at 35 ug/ml (Rvb = 0.95 +/-0.02 no_unit)
|
Spodoptera frugiperda
|
0.71
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as growth index at 20 ug/ml (Rvb = 0.95 +/-0.02 no_unit)
|
Spodoptera frugiperda
|
0.91
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as growth index at 10 ug/ml (Rvb = 0.95 +/-0.02 no_unit)
|
Spodoptera frugiperda
|
0.93
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as growth index at 5 ug/ml (Rvb = 0.95 +/-0.02 no_unit)
|
Spodoptera frugiperda
|
0.97
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as reduction in adult emergence at 35 ug/ml
|
Spodoptera frugiperda
|
0.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as reduction in adult emergence at 20 ug/ml
|
Spodoptera frugiperda
|
0.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as reduction in pupae weight at 25 ug/ml
|
Spodoptera frugiperda
|
None
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against Spodoptera frugiperda (fall armyworm) larvae fed with compound containing diet assessed as reduction in survival pupation at >35 ug/ml
|
Spodoptera frugiperda
|
0.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against Drosophila melanogaster larvae fed with compound incorporated diet assessed as mortality at 100 ug/ml after 72 hr by not choice test (Rvb = 0%)
|
Drosophila melanogaster
|
82.9
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against Drosophila melanogaster larvae fed with compound incorporated diet assessed as mortality at 50 ug/ml after 72 hr by not choice test (Rvb = 0%)
|
Drosophila melanogaster
|
77.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against Drosophila melanogaster larvae fed with compound incorporated diet assessed as mortality at 20 ug/ml after 72 hr by not choice test (Rvb = 0%)
|
Drosophila melanogaster
|
67.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against Drosophila melanogaster larvae fed with compound incorporated diet assessed as mortality at 10 ug/ml after 72 hr by not choice test (Rvb = 0%)
|
Drosophila melanogaster
|
13.3
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Acute toxicity against last larval stage of Spodoptera frugiperda (fall armyworm) assessed as mortality applied topically onto abdomen measured after 7 days
|
Spodoptera frugiperda
|
17.5
ug ml-1
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Acute toxicity against last larval stage of Spodoptera frugiperda (fall armyworm) assessed as survival at 70 ug/ml applied topically onto abdomen measured after 24 hr (Rvb = 98.8 +/-3.5%)
|
Spodoptera frugiperda
|
0.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Acute toxicity against last larval stage of Spodoptera frugiperda (fall armyworm) assessed as survival at 50 ug/ml applied topically onto abdomen measured after 24 hr (Rvb = 98.8 +/-3.5%)
|
Spodoptera frugiperda
|
3.9
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Acute toxicity against last larval stage of Spodoptera frugiperda (fall armyworm) assessed as survival at 35 ug/ml applied topically onto abdomen measured after 24 hr (Rvb = 98.8 +/-3.5%)
|
Spodoptera frugiperda
|
6.9
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Acute toxicity against last larval stage of Spodoptera frugiperda (fall armyworm) assessed as survival at 20 ug/ml applied topically onto abdomen measured after 24 hr (Rvb = 98.8 +/-3.5%)
|
Spodoptera frugiperda
|
51.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Acute toxicity against last larval stage of Spodoptera frugiperda (fall armyworm) assessed as survival at 10 ug/ml applied topically onto abdomen measured after 24 hr (Rvb = 98.8 +/-3.5%)
|
Spodoptera frugiperda
|
69.1
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Acute toxicity against last larval stage of Spodoptera frugiperda (fall armyworm) assessed as survival at 5 ug/ml applied topically onto abdomen measured after 24 hr (Rvb = 98.8 +/-3.5%)
|
Spodoptera frugiperda
|
75.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 50 ug/ml after 21 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
44.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 35 ug/ml after 21 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
25.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 20 ug/ml after 21 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
15.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 10 ug/ml after 21 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
5.6
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 5 ug/ml after 21 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
4.16
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 50 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
37.4
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 35 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
37.4
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 20 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
41.8
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 10 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
59.4
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 5 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
85.6
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 50 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
33.6
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 35 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
38.2
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 20 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
50.6
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 10 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
65.8
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 5 ug/ml after 21 days (Rvb = 100%)
|
Spodoptera frugiperda
|
93.5
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 50 ug/ml after 7 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
83.3
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 20 ug/ml after 7 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
46.8
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 35 ug/ml after 7 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
63.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 10 ug/ml after 7 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
41.7
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Insecticidal activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as mortality at 5 ug/ml after 7 days (Rvb = 5.6%)
|
Spodoptera frugiperda
|
33.3
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 35 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
42.5
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 50 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
33.3
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 20 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
64.2
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 10 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
79.0
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as length gained at 5 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
88.3
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 50 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
41.3
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 35 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
42.3
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 20 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
56.2
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 10 ug/ml after 7 days (Rvb = 100%)
|
Spodoptera frugiperda
|
81.3
%
|
|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
|
Growth inhibitory activity against first-instar larval stage of Spodoptera frugiperda (fall armyworm) fed with compound incorporated diet assessed as weight gained at 5 ug/ml after 7 days (Rvb = 100%)
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Spodoptera frugiperda
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89.5
%
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|
Journal : Ind Crops Prod
Title : Insect growth regulatory effects by diterpenes from Calceolaria talcana Grau & Ehrhart (Calceolariaceae: Scrophulariaceae) against Spodoptera frugiperda and Drosophila melanogaster
Year : 2013
Volume : 45
First Page : 283
Last Page : 292
Authors : Muñoz E, Carlos L. Céspedes, Daniela Escalona, Juan R. Salazar, Julio Alarcon.
Abstract : The n-hexane extract from aerial parts of Calceolaria talcana (Calceolariaceae, formerly Scrophulariaceae) afforded 1,10-α-cyclopropyl-4,13-dimethyl-19-α-hydroxy-9-epi-ent-7,15-isopimaradiene (1,10-cyclopropyl-9-epi-ent-isopimarol) 1, and 19α-hydroxy-8,11,13-abietatriene 2 together with other known triterpenes and naphthoquinones. These natural products together with n-hexane extract and several fractions showed insecticidal and insect growth regulatory activity against fall armyworm (Spodoptera frugiperda, Lepidoptera: Noctuidae), and fruit fly (Drosophila melanogaster, Diptera: Drosophilidae), insect pests of corn and fruits, respectively. The most active samples were a mixture (M1) of the diterpenes 1+2 (6:4) that showed insecticidal activity between 10 and 20ppm. Additionally, a mixture of triterpenes 3–5 (M2), fraction 5 (F-5), a mixture of two naphthoquinones 6, 7 (M3), and the n-hexane extract, which had significant effects between 20.0 and 35.0μg/mL in diets. Almost all samples were insecticidal with lethal doses between 35 and 50μg/mL. Our results indicate that these compounds at low concentrations appear to have selective effects on the pre-emergence metabolism of the insect. The results were fully comparable to known natural insect growth inhibitors such as gedunin, MeOH-Cedrela and MeOH-Yucca extracts, suggesting a possible role as natural insecticidal agents.
