EcoDrugPlus


Synonyms	Viloxazin Viloxazine
Status
Molecule Category	Free-form
ATC	N06AX09
UNII	5I5Y2789ZF
EPA CompTox	DTXSID6057900


InChI Key	YWPHCCPCQOJSGZ-UHFFFAOYSA-N
Smiles	CCOc1ccccc1OCC1CNCCO1
InChI	InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3

Property Name	Value
Molecular Formula	C13H19NO3
Molecular Weight	237.3
AlogP	1.45
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	5.0
Polar Surface Area	39.72
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	17.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family	-	-	155-155	170	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Sus scrofa	-	220	-	-	-

Resources	Reference
ChEBI	94405
ChEMBL	CHEMBL306700
DrugBank	DB09185
DrugCentral	2820
FDA SRS	5I5Y2789ZF
PubChem	5666
SureChEMBL	SCHEMBL34168

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

VILOXAZINE

Structure

Physicochemical Descriptors

Pharmacology

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