| Synonyms | |
| Status | |
| Molecule Category | UNKNOWN |
| UNII | 5H681S8O3S |
Structure
| InChI Key | CVASBKDYSQKLSO-UHFFFAOYSA-N |
|---|---|
| Smiles | |
| InChI |
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Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C18H21NS |
| Molecular Weight | 283.44 |
| AlogP | 4.61 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 3.0 |
| Polar Surface Area | 12.03 |
| Molecular species | BASE |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 20.0 |
Bioactivity
| Mechanism of Action | Action | Reference |
|---|---|---|
| Alpha-1a adrenergic receptor antagonist | ANTAGONIST | Other Wikipedia Other |
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Protein: Serotonin 3 (5-HT3) receptor Description: 5-hydroxytryptamine receptor 3E Organism : Homo sapiens A5X5Y0 ENSG00000186038 |
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Protein: Serotonin 3 (5-HT3) receptor Description: 5-hydroxytryptamine receptor 3B Organism : Homo sapiens O95264 ENSG00000149305 |
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Protein: Norepinephrine transporter Description: Sodium-dependent noradrenaline transporter Organism : Homo sapiens P23975 ENSG00000103546 |
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Protein: Serotonin 2a (5-HT2a) receptor Description: 5-hydroxytryptamine receptor 2A Organism : Homo sapiens P28223 ENSG00000102468 |
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Protein: Serotonin 2c (5-HT2c) receptor Description: 5-hydroxytryptamine receptor 2C Organism : Homo sapiens P28335 ENSG00000147246 |
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Protein: Serotonin transporter Description: Sodium-dependent serotonin transporter Organism : Homo sapiens P31645 ENSG00000108576 |
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Protein: Alpha-1a adrenergic receptor Description: Alpha-1A adrenergic receptor Organism : Homo sapiens P35348 ENSG00000120907 |
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Protein: Serotonin 3 (5-HT3) receptor Description: 5-hydroxytryptamine receptor 3A Organism : Homo sapiens P46098 ENSG00000166736 |
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Protein: Dopamine transporter Description: Sodium-dependent dopamine transporter Organism : Homo sapiens Q01959 ENSG00000142319 |
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Protein: Serotonin 3 (5-HT3) receptor Description: 5-hydroxytryptamine receptor 3D Organism : Homo sapiens Q70Z44 ENSG00000186090 |
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Protein: Serotonin 3 (5-HT3) receptor Description: 5-hydroxytryptamine receptor 3C Organism : Homo sapiens Q8WXA8 ENSG00000178084 |
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Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL2104986 |
| DrugBank | DB12641 |
| FDA SRS | 5H681S8O3S |
| PubChem | 9878913 |
| SureChEMBL | SCHEMBL547653 |
| ZINC | ZINC000034003654 |
CONTENTS