EcoDrugPlus


Synonyms	(-)-praziquantel (r)-(-)-praziquantel (r)-praziquantel Arpraziquantel L-praziquantel L-pzq MSC-2499550A MSC2499550A Msc2499550a Praziquantel, (-)- Praziquantel, (r)-
Status
Molecule Category	Free-form
UNII	WF15T5925V

Synonyms

(-)-praziquantel

(r)-(-)-praziquantel

(r)-praziquantel

Arpraziquantel

L-praziquantel

L-pzq

MSC-2499550A

MSC2499550A

Msc2499550a

Praziquantel, (-)-

Praziquantel, (r)-

Status

Molecule Category

Free-form

UNII

WF15T5925V


InChI Key	FSVJFNAIGNNGKK-KRWDZBQOSA-N
Smiles	O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3[C@@H]2C1
InChI	InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2/t17-/m0/s1

InChI Key

FSVJFNAIGNNGKK-KRWDZBQOSA-N

Smiles

O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3[C@@H]2C1

InChI

InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2/t17-/m0/s1

Property Name	Value
Molecular Formula	C19H24N2O2
Molecular Weight	312.41
AlogP	2.53
Hydrogen Bond Acceptor	2.0
Number of Rotational Bond	1.0
Polar Surface Area	40.62
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	23.0

Property Name

Value

Molecular Formula

C19H24N2O2

Molecular Weight

312.41

AlogP

2.53

Hydrogen Bond Acceptor

2.0

Number of Rotational Bond

1.0

Polar Surface Area

40.62

Molecular species

NEUTRAL

Aromatic Rings

1.0

Heavy Atoms

23.0

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Schistosoma mansoni	500	-	-	-	-

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Schistosoma mansoni

500

Resources	Reference
ChEMBL	CHEMBL1235551
DrugBank	DB11749
FDA SRS	WF15T5925V
PDB	PZQ
SureChEMBL	SCHEMBL16019898
ZINC	ZINC000000000655

Resources

Reference

ChEMBL

DrugBank

FDA SRS

PDB

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

PRAZIQUANTEL, (R)-

Structure

Physicochemical Descriptors

Pharmacology

Cross References