|
Inhibition of diphenolase activity of mushroom tyrosinase at 0.055 mM
|
Agaricus bisporus
|
12.65
%
|
|
|
Inhibition of guinea pig classical complement system assessed as hemolysis of sensitized sheep erythrocytes at 1000 uM
|
Cavia porcellus
|
54.4
%
|
|
|
Inhibition of human plasma alternative complement system assessed as hemolysis of non-sensitized rabbit erythrocytes at 1000 uM
|
Homo sapiens
|
18.0
%
|
|
|
Toxicity in Salmonella Typhimurium T98 at 600 ug/plate after 72 hrs by Ames assay in presence of Ames S-9 fraction
|
Salmonella enterica subsp. enterica serovar Typhimurium
|
20.0
%
|
|
|
Toxicity in Salmonella Typhimurium T98 at 300 ug/plate after 72 hrs by Ames assay in presence of Ames S-9 fraction
|
Salmonella enterica subsp. enterica serovar Typhimurium
|
20.0
%
|
|
|
Antimutagenic activity in Salmonella Typhimurium T98 assessed as inhibition of 2-aminoanthracene-induced mutation at 600 ug/plate after 72 hrs in presence of Ames S-9 fraction
|
Salmonella enterica subsp. enterica serovar Typhimurium
|
0.0
%
|
|
|
Inhibition of COX2 at 100 uM by scintillation proximity assay
|
None
|
30.0
%
|
|
|
Inhibition of Saccharomyces cerevisiae fatty acid synthase
|
Saccharomyces cerevisiae
|
50.0
ug.mL-1
|
|
|
Antifungal activity against Candida albicans ATCC 90028
|
Candida albicans
|
50.0
ug.mL-1
|
|
|
Antifungal activity against Cryptococcus neoformans ATCC 90113
|
Cryptococcus neoformans
|
30.0
ug.mL-1
|
|
|
Antiprotozoal activity against Entamoeba histolytica HM-1:IMSS trophozoites after 48 hrs by MTT/PMS assay
|
Entamoeba histolytica HM-1:IMSS
|
119.7
ug.mL-1
|
|
|
Antiprotozoal activity against Giardia lamblia IMSS:0989:1 after 48 hrs by MTT/PMS assay
|
Giardia intestinalis
|
178.7
ug.mL-1
|
|
|
Inhibition of TPA-induced EBV-early antigen activation in human Raji cells relative to TPA
|
Human herpesvirus 4
|
578.0
molar ratio
|
|
|
Antioxidant activity assessed as DPPH radical scavenging activity after 20 mins by UV-visible spectrophotometry
|
None
|
4.8
ug
|
|
|
Inhibition of theophylline-stimulated melanogenesis in mouse B16-4A5 cells at 30 uM after 72 hrs
|
Mus musculus
|
5.2
%
|
|
|
Inhibition of theophylline-stimulated melanogenesis in mouse B16-4A5 cells at 10 uM after 72 hrs
|
Mus musculus
|
4.3
%
|
|
|
Inhibition of theophylline-stimulated melanogenesis in mouse B16-4A5 cells at 3 uM after 72 hrs
|
Mus musculus
|
3.1
%
|
|
|
Inhibition of theophylline-stimulated melanogenesis in mouse B16-4A5 cells at 1 uM after 72 hrs
|
Mus musculus
|
4.5
%
|
|
|
Toxicity in mouse B16-4A5 cells assessed as inhibition of cell proliferation at 30 uM in presence of 1 mM theophylline after 72 hrs by WST8 dye reduction assay
|
Mus musculus
|
8.8
%
|
|
|
Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assay
|
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
|
31.14
ug.mL-1
|
|
|
Antioxidant activity assessed as DPPH free radical scavenging activity
|
None
|
15.5
ug
|
|
|
Inhibition of bovine kidney LMW-PTPase at 400 uM using pNPP substrate
|
Bos taurus
|
14.0
%
|
|
|
Inhibition of electric eel AChE at 2 mg/ml by Ellman's method
|
Electrophorus electricus
|
-0.25
%
|
|
|
Inhibition of horse BChE at 2 mg/ml by Ellman's method
|
Equus caballus
|
4.32
%
|
|
|
Antioxidant activity assessed as inhibition of xanthine-xanthine oxidase generated superoxide anion radical production at 200 ug/ml after 30 min by NBT reduction assay
|
None
|
35.0
%
|
|
|
Antioxidant activity assessed as inhibition of xanthine-xanthine oxidase generated superoxide anion radical production at 100 ug/ml after 30 min by NBT reduction assay
|
None
|
18.0
%
|
|
|
Antifungal activity against Verticillium dahliae assessed as inhibition of mycelial radial growth measured after 350 hr
|
Verticillium dahliae
|
80.0
ug.mL-1
|
|
|
Antioxidant activity assessed as ABTS radical scavenging activity
|
None
|
4.65
ug.mL-1
|
|
|
Antioxidant activity assessed as DPPH radical scavenging activity after 30 min
|
None
|
1.83
ug.mL-1
|
|
|
Antiamoebic activity against Entamoeba histolytica
|
Entamoeba histolytica
|
120.7
ug.mL-1
|
|
|
Inhibition of trypsin (unknown origin) using BApNA as substrate at 2 mg/ml incubated for 15 min prior to substrate addition measured after 30 min by UV/VIS spectrophotometric analysis
|
Homo sapiens
|
75.2
%
|
|
|
Inhibition of AChE (unknown origin)
|
Homo sapiens
|
12.0
nM
|
|
|
Inhibition of TRAP activity in RANKL-induced Balb/c mouse RAW264.7 cells at 10 uM after 1 hr by ELISA relative to control
|
Mus musculus
|
71.68
%
|
|
|
Inhibition of TRAP activity in Balb/c mouse RAW264.7 cells at 10 uM after 1 hr by ELISA relative to control
|
Mus musculus
|
145.67
%
|
|
|
Inhibition of TRAP activity in RANKL-induced Balb/c mouse RAW264.7 cells at 1 uM after 1 hr by ELISA relative to control
|
Mus musculus
|
78.02
%
|
|
|
Inhibition of TRAP activity in Balb/c mouse RAW264.7 cells at 1 uM after 1 hr by ELISA relative to control
|
Mus musculus
|
158.55
%
|
|
|
Inhibition of sEH (unknown origin) assessed as substrate PHOME hydrolysis at 25 uM after 1 hr by fluorescence method
|
Homo sapiens
|
40.0
%
|
|
|
Inhibition of alpha-amylase (unknown origin) relative to control
|
Homo sapiens
|
20.1
%
|
|
|
Inhibition of Mycobacterium tuberculosis MTCC 300 DAH7PS expressed in Escherichia coli BL21 (DE3) using 25 to 125 uM PEP/100 uM E4P as substrate at 10 uM by spectrophotometric analysis relative to control
|
Mycobacterium tuberculosis
|
17.0
%
|
|
|
Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020); MIC in CAMBH media, using NBS plates, by OD(600)
|
Staphylococcus aureus subsp. aureus
|
17.86
%
|
|
|
Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CAMBH media using NBS plates, by OD(600)
|
Escherichia coli
|
2.05
%
|
|
|
Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); MIC in CAMBH media using NBS plates, by OD(600)
|
Klebsiella pneumoniae
|
10.13
%
|
|
|
Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 (CO-ADD:GN_042); MIC in CAMBH media using NBS plates, by OD(600)
|
Pseudomonas aeruginosa
|
17.85
%
|
|
|
Antibacterial activity against Acinetobacter baumannii ATCC 19606 (CO-ADD:GN_034); MIC in CAMBH media using NBS plates, by OD600
|
Acinetobacter baumannii
|
25.94
%
|
|
|
Antifungal activity against Candida albicans ATCC 90028 (CO-ADD:FG_001); MIC in YNB media using NBS plates, by OD630
|
Candida albicans
|
3.37
%
|
|
|
Antifungal activity against Cryptococcus neoformans H99 ATCC 208821 (CO-ADD:FG_002); MIC in YNB media using NBS plates, by Resazurin OD(600-570)
|
Cryptococcus neoformans
|
-5.7
%
|
|
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
|
Homo sapiens
|
40.82
%
|
|
|
Inhibition of Enterobacter cloacae beta-lactamase at 500 uM incubated for 10 mins followed by nitrocefin substrate challenge and measured for 5 mins by spectrophotometric analysis relative to control
|
Enterobacter cloacae
|
15.0
%
|
|
|
Anti-colitis activity in ICR mouse model of DSS-induced colitis assessed as inhibition of DSS-induced colorectum shortening at 6 mg, po for 14 days relative to control
|
Mus musculus
|
73.0
%
|
|
|
Inhibition of F1F0-ATP synthase in Escherichia coli after 60 mins relative to control
|
Escherichia coli
|
40.0
%
|
|
|
SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate
|
Severe acute respiratory syndrome coronavirus 2
|
12.75
%
|
|
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
|
Chlorocebus sabaeus
|
-0.08
%
|
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
|
Chlorocebus sabaeus
|
-0.08
%
|
|
|
Inhibition of human liver FBP1 at 200 uM incubated for 5 mins by fluorescence method relative to control
|
Homo sapiens
|
20.0
%
|
|
|
Inhibition of cytochrome c (unknown origin) assessed as reduction in cyt c-CL complex formation at 10 uM incubated for 15 mins in presence of cardiolipin by Trp-59 fluorescence assay relative to control
|
Homo sapiens
|
66.0
%
|
|
|
Inhibition of cytochrome c (unknown origin) assessed as reduction in cyt c-CL peroxidase activity at 10 uM up to 20 mins in presence of cardiolipin by Amplex red staining based fluorescence assay relative to control
|
Homo sapiens
|
28.0
%
|
|
|
Inhibition of cytochrome c (unknown origin) assessed as reduction reduction of cyt c from its ferric state to ferrous state at 10 uM incubated for 20 mins in presence of cardiolipin by UV-vis Spectrophotometric assay relative to control
|
Homo sapiens
|
19.0
%
|
|
