EcoDrugPlus


Synonyms	CPHPC Cphpc GSK-2315698 GSK2315698 Gsk2315698 Miridesap RO-638695 Ro 63-8695
Status
Molecule Category	Free-form
UNII	WO97N24A47
EPA CompTox	DTXSID00176996

Datasets:

Active Pharmaceutical Ingredients

Bioactive chemicals

Agrochemicals

Human Metabolites

Search:

Exact

Similarity

SubStructure

Threshold (%) >= 70


InChI Key	HZLAWYIBLZNRFZ-VXGBXAGGSA-N
Smiles	O=C(O)[C@H]1CCCN1C(=O)CCCCC(=O)N1CCC[C@@H]1C(=O)O
InChI	InChI=1S/C16H24N2O6/c19-13(17-9-3-5-11(17)15(21)22)7-1-2-8-14(20)18-10-4-6-12(18)16(23)24/h11-12H,1-10H2,(H,21,22)(H,23,24)/t11-,12-/m1/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C16H24N2O6
Molecular Weight	340.38
AlogP	0.7
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	7.0
Polar Surface Area	115.22
Molecular species	ACID
Aromatic Rings	0.0
Heavy Atoms	24.0

Mechanism of Action	Action	Reference
Serum amyloid P-component cross-linking agent	CROSS-LINKING AGENT	PubMed

Target Conservation


Protein: Serum amyloid P-component Description: Serum amyloid P-component Organism : Homo sapiens P02743 ENSG00000132703

Cross References

Resources	Reference
ChEMBL	CHEMBL25263
DrugBank	DB13087
FDA SRS	WO97N24A47
Guide to Pharmacology	8256
PDB	GHE
PubChem	125516
SureChEMBL	SCHEMBL1537496
ZINC	ZINC000003972138

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

MIRIDESAP

Structure

Physicochemical Descriptors

Pharmacology

Target Conservation

Related Entries

Cross References