EcoDrugPlus


Synonyms	L-serine NSC-118365 Serine
Status
Molecule Category	Free-form
UNII	452VLY9402
EPA CompTox	DTXSID60883230

Synonyms

L-serine

NSC-118365

Serine

Status

Molecule Category

Free-form

UNII

452VLY9402

EPA CompTox

DTXSID60883230


InChI Key	MTCFGRXMJLQNBG-REOHCLBHSA-N
Smiles	N[C@@H](CO)C(=O)O
InChI	InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI Key

MTCFGRXMJLQNBG-REOHCLBHSA-N

Smiles

N[C@@H](CO)C(=O)O

InChI

InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

Property Name	Value
Molecular Formula	C3H7NO3
Molecular Weight	105.09
AlogP	-1.61
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	3.0
Number of Rotational Bond	2.0
Polar Surface Area	83.55
Molecular species	ZWITTERION
Aromatic Rings	0.0
Heavy Atoms	7.0

Property Name

Value

Molecular Formula

C3H7NO3

Molecular Weight

105.09

AlogP

-1.61

Hydrogen Bond Acceptor

3.0

Hydrogen Bond Donor

3.0

Number of Rotational Bond

2.0

Polar Surface Area

83.55

Molecular species

ZWITTERION

Aromatic Rings

0.0

Heavy Atoms

7.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Hydrolase	-	15-16	-	-	-

Targets

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Enzyme Hydrolase

15-16

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Electrophorus electricus	-	15	-	-	-
Equus caballus	-	16	-	-	-

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Electrophorus electricus

Equus caballus

Resources	Reference
ChEBI	33384
ChEMBL	CHEMBL11298
DrugBank	DB00133
DrugCentral	4127
FDA SRS	452VLY9402
Human Metabolome Database	HMDB0000187
Guide to Pharmacology	726
KEGG	C00065
PDB	SER
PharmGKB	PA451330
PubChem	5951
SureChEMBL	SCHEMBL1775
ZINC	ZINC000000895034

Resources

Reference

ChEBI

ChEMBL

DrugBank

DrugCentral

FDA SRS

Human Metabolome Database

HMDB0000187

Guide to Pharmacology

KEGG

PDB

PharmGKB

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

SERINE

Structure

Physicochemical Descriptors

Pharmacology

Cross References