RAZUPROTAFIB

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Synonyms
Status
Molecule Category Free-form
UNII 0WAX4UT396

Structure

InChI Key KWJDHELCGJFUHW-SFTDATJTSA-N
Smiles COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(=O)(=O)O)cc1)c1csc(-c2cccs2)n1
InChI
InChI=1S/C26H26N4O6S3/c1-36-26(32)29-21(15-17-6-3-2-4-7-17)24(31)27-20(22-16-38-25(28-22)23-8-5-13-37-23)14-18-9-11-19(12-10-18)30-39(33,34)35/h2-13,16,20-21,30H,14-15H2,1H3,(H,27,31)(H,29,32)(H,33,34,35)/t20-,21-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C26H26N4O6S3
Molecular Weight 586.72
AlogP 4.45
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 11.0
Polar Surface Area 146.72
Molecular species ACID
Aromatic Rings 4.0
Heavy Atoms 39.0

Pharmacology

Mechanism of Action Action Reference
Receptor-type tyrosine-protein phosphatase beta inhibitor INHIBITOR PubMed PubMed

Target Conservation

Protein: Receptor-type tyrosine-protein phosphatase beta
Description: Receptor-type tyrosine-protein phosphatase beta
Organism : Homo sapiens
P23467 ENSG00000127329

Cross References

Resources Reference
ChEMBL CHEMBL3931971
DrugBank DB16353
FDA SRS 0WAX4UT396
PubChem 46700782
SureChEMBL SCHEMBL679459
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