LY2828360

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Synonyms
Status
Molecule Category Free-form
UNII O12H7VFU6P

Structure

InChI Key UCMNDPDJRSEZPL-UHFFFAOYSA-N
Smiles Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n(C3CCOCC3)c2n1
InChI
InChI=1S/C22H27ClN6O/c1-15-24-21(28-11-9-27(2)10-12-28)19-22(25-15)29(16-7-13-30-14-8-16)20(26-19)17-5-3-4-6-18(17)23/h3-6,16H,7-14H2,1-2H3

Pharmacology

Mechanism of Action Action Reference
Cannabinoid CB2 receptor agonist AGONIST Other
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Lipid-like ligand receptor (family A GPCR) Cannabinoid receptor
20-20.1 - - 37-40 -
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Homo sapiens
20-20.1 - - 37-40 -
Rattus norvegicus
- - - 37-40 85

Target Conservation

Protein: Cannabinoid CB2 receptor
Description: Cannabinoid receptor 2
Organism : Homo sapiens
P34972 ENSG00000188822

Cross References

Resources Reference
ChEMBL CHEMBL3545033
FDA SRS O12H7VFU6P
CONTENTS