Inhibitory activity derived from Anastatica hierochuntica on D-Gal-induced cytotoxicity in primary cultured mouse hepatocytes at a concentration of 0 uM
|
Mus musculus
|
0.0
%
|
|
Inhibitory activity derived from Anastatica hierochuntica on D-Gal-induced cytotoxicity in primary cultured mouse hepatocytes at a concentration of 10 uM
|
Mus musculus
|
7.7
%
|
|
Inhibitory activity derived from Anastatica hierochuntica on D-Gal-induced cytotoxicity in primary cultured mouse hepatocytes at a concentration of 3 uM
|
Mus musculus
|
4.8
%
|
|
Inhibitory activity derived from Anastatica hierochuntica on D-Gal-induced cytotoxicity in primary cultured mouse hepatocytes at a concentration of 30 uM
|
Mus musculus
|
45.2
%
|
|
Hepatoprotective activity against D-galactosamine/TNFalpha-induced cell death in primary cultured mouse hepatocytes at 100 uM treated for 30 mins before TNFalpha challenge measured after 18 hrs by MTT assay relative to control
|
Mus musculus
|
129.0
%
|
|
Hepatoprotective activity against D-galactosamine/TNFalpha-induced cell death in primary cultured mouse hepatocytes at 50 uM treated for 30 mins before TNFalpha challenge measured after 18 hrs by MTT assay relative to control
|
Mus musculus
|
68.2
%
|
|
Hepatoprotective activity against D-galactosamine/TNFalpha-induced cell death in primary cultured mouse hepatocytes at 25 uM treated for 30 mins before TNFalpha challenge measured after 18 hrs by MTT assay relative to control
|
Mus musculus
|
44.9
%
|
|
Hepatoprotective activity in mouse hepatocytes assessed inhibition of D-galactosamine/TNFalpha-induced cell death at 12.5 uM administered before 30 mins of TNFalpha challenge measured after 18 hrs
|
Mus musculus
|
43.4
%
|
|
Hepatoprotective activity in mouse hepatocytes assessed inhibition of D-galactosamine/TNFalpha-induced cell death at 25 uM administered before 30 mins of TNFalpha challenge measured after 18 hrs
|
Mus musculus
|
99.7
%
|
|
Hepatoprotective activity in mouse hepatocytes assessed inhibition of D-galactosamine/TNFalpha-induced cell death at 50 uM administered before 30 mins of TNFalpha challenge measured after 18 hrs
|
Mus musculus
|
149.7
%
|
|
Hepatoprotective activity against mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cell death at 25 uM after 18 hrs by MTT assay
|
Mus musculus
|
38.1
%
|
|
Hepatoprotective activity against mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cell death at 50 uM after 18 hrs by MTT assay
|
Mus musculus
|
61.2
%
|
|
Hepatoprotective activity against mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cell death at 100 uM after 18 hrs by MTT assay
|
Mus musculus
|
96.5
%
|
|
Hepatoprotective activity against mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cell death at 200 uM after 18 hrs by MTT assay
|
Mus musculus
|
70.8
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 3 uM after 44 hrs by MTT assay relative to control
|
Mus musculus
|
4.8
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 10 uM after 44 hrs by MTT assay relative to control
|
Mus musculus
|
7.7
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 30 uM after 44 hrs by MTT assay relative to control
|
Mus musculus
|
45.2
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 100 uM after 44 hrs by MTT assay relative to control
|
Mus musculus
|
77.0
%
|
|
Inhibition of bovine xanthine oxidase assessed as reduction in xanthine turnover at 10 uM
|
Bos taurus
|
50.0
%
|
|
Inhibition of bovine xanthine oxidase assessed as reduction in xanthine turnover at 25 uM
|
Bos taurus
|
50.0
%
|
|
Inhibition of bovine xanthine oxidase assessed as reduction in xanthine turnover at 50 uM
|
Bos taurus
|
50.0
%
|
|
Inhibition of bovine xanthine oxidase assessed as decrease in production of superoxide at 50 uM relative to control
|
Bos taurus
|
20.0
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 3 uM after 44 hrs by MTT assay relative to untreated control
|
Mus musculus
|
5.0
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 10 uM after 44 hrs by MTT assay relative to untreated control
|
Mus musculus
|
8.0
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 30 uM after 44 hrs by MTT assay relative to untreated control
|
Mus musculus
|
45.0
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 100 uM after 44 hrs by MTT assay relative to untreated control
|
Mus musculus
|
77.0
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity at 1 uM after 20 hrs by MTT assay relative to untreated control
|
Mus musculus
|
11.0
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity at 3 uM after 20 hrs by MTT assay relative to untreated control
|
Mus musculus
|
19.0
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity at 10 uM after 20 hrs by MTT assay relative to untreated control
|
Mus musculus
|
37.0
%
|
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity at 30 uM after 20 hrs by MTT assay relative to untreated control
|
Mus musculus
|
93.0
%
|
|
Hepatoprotective activity in ddY mouse primary cultured hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 3 ug/mL after 44 hrs by MTT assay
|
Mus musculus
|
4.8
%
|
|
Hepatoprotective activity in ddY mouse primary cultured hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 10 ug/mL after 44 hrs by MTT assay
|
Mus musculus
|
7.7
%
|
|
Hepatoprotective activity in ddY mouse primary cultured hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 30 ug/mL after 44 hrs by MTT assay
|
Mus musculus
|
45.2
%
|
|
Hepatoprotective activity in ddY mouse primary cultured hepatocytes assessed as inhibition of D-galactosamine-induced cytotoxicity at 100 ug/mL after 44 hrs by MTT assay
|
Mus musculus
|
77.0
%
|
|
Cytoprotective activity in mouse L929 cells assessed as inhibition of TNF-alpha-induced cytotoxicity at 3 ug/mL after 44 hrs by MTT assay
|
Mus musculus
|
5.3
%
|
|
Cytoprotective activity in mouse L929 cells assessed as inhibition of TNF-alpha-induced cytotoxicity at 10 ug/mL after 44 hrs by MTT assay
|
Mus musculus
|
22.0
%
|
|
Cytoprotective activity in mouse L929 cells assessed as inhibition of TNF-alpha-induced cytotoxicity at 30 ug/mL after 44 hrs by MTT assay
|
Mus musculus
|
48.0
%
|
|
Cytoprotective activity in mouse L929 cells assessed as inhibition of TNF-alpha-induced cytotoxicity at 100 ug/mL after 44 hrs by MTT assay
|
Mus musculus
|
50.8
%
|
|
Cytoprotective activity in mouse L929 cells assessed as inhibition of TNF-alpha-induced cytotoxicity after 44 hrs by MTT assay
|
Mus musculus
|
60.4
ug.mL-1
|
|
Cytoprotective activity in human embryo L02 cells assessed as inhibition of D-galactosamine-induced cytotoxicity at 6.25 ug/ml treated for 1 hr prior to D-galactosamine challenge measured after 48 hrs by MTT assay relative to control
|
Homo sapiens
|
28.2
%
|
|
Cytoprotective activity in human embryo L02 cells assessed as inhibition of D-galactosamine-induced cytotoxicity at 3.13 ug/ml treated for 1 hr prior to D-galactosamine challenge measured after 48 hrs by MTT assay relative to control
|
Homo sapiens
|
33.4
%
|
|
Cytoprotective activity in human embryo L02 cells assessed as inhibition of D-galactosamine-induced cytotoxicity at 1.56 ug/ml treated for 1 hr prior to D-galactosamine challenge measured after 48 hrs by MTT assay relative to control
|
Homo sapiens
|
10.1
%
|
|
Inhibition of electric eel AChE at 2 mg/ml by Ellman's method
|
Electrophorus electricus
|
7.08
%
|
|
Inhibition of horse BChE at 2 mg/ml by Ellman's method
|
Equus caballus
|
-7.94
%
|
|
Inhibition of electric eel AChE at 100 uM by colorimetric Ellman assay
|
Electrophorus electricus
|
5.5
%
|
|
Inhibition of horse AChE at 100 uM by colorimetric Ellman assay
|
Equus caballus
|
3.1
%
|
|
Inhibition of human thrombin assessed as decrease in platelet aggregation at 1000 uM preincubated for 10 mins measured for 10 mins by dual channel chrono-log aggregometric analysis relative to control
|
Homo sapiens
|
43.0
%
|
|
Inhibition of Wnt/beta-catenin signaling pathway in human HEK293 cells at 20 uM after 24 hrs by dual luciferase reporter gene assay relative to vehicle-treated control
|
Homo sapiens
|
8.3
%
|
|
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
|
Cricetulus griseus
|
54.77
%
|
|
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
|
Cricetulus griseus
|
46.89
%
|
|
Inhibition of biofilm formation in Staphylococcus aureus 8325-4 after 24 hrs by microtiter plate assay
|
Staphylococcus aureus
|
64.0
ug.mL-1
|
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production at 1 uM after 24 hrs by ELISA relative to control
|
Mus musculus
|
10.3
%
|
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production at 10 uM after 24 hrs by ELISA relative to control
|
Mus musculus
|
27.0
%
|
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production at 50 uM after 24 hrs by ELISA relative to control
|
Mus musculus
|
47.0
%
|
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production at 100 uM after 24 hrs by ELISA relative to control
|
Mus musculus
|
53.8
%
|
|
Inhibition of amyloid beta 42 (unknown origin) expressed in Escherichia coli BL21 (DE3) aggregation at 10 uM incubated for overnight by Th-S fluorescence staining based UV-Vis spectrophotometer (Rvb = 0 +/- 1%)
|
Homo sapiens
|
4.8
%
|
|
Inhibition of amyloid beta 42 (unknown origin) expressed in Escherichia coli BL21 (DE3) aggregation at 100 uM incubated for overnight by Th-S fluorescence staining based UV-Vis spectrophotometer (Rvb = 0 +/- 4.4%)
|
Homo sapiens
|
16.0
%
|
|
Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli (DE3) at 10 uM incubated for overnight by Th-S fluorescence staining based UV-Vis spectrophotometer (Rvb = 0.0 +/- 1.4%)
|
Homo sapiens
|
2.0
%
|
|
Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli (DE3) at 100 uM incubated for overnight by Th-S fluorescence staining based UV-Vis spectrophotometer (Rvb = 0.0 +/- 2.4%)
|
Homo sapiens
|
10.1
%
|
|
Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectrophotometry based Dixon plot analysis
|
Agaricus bisporus
|
700.0
nM
|
|
Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectrophotometry
|
Agaricus bisporus
|
700.0
nM
|
|
Inhibition of F1F0-ATP synthase in Escherichia coli after 60 mins relative to control
|
Escherichia coli
|
100.0
%
|
|