RAVIDASVIR

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Synonyms
C5
Status
Molecule Category Free-form
UNII AL3G001BI8

Structure

InChI Key LCHMHYPWGWYXEL-ZYADHFCISA-N
Smiles COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc3cc(-c4ccc5[nH]c([C@@H]6CCCN6C(=O)[C@@H](NC(=O)OC)C(C)C)nc5c4)ccc3c2)c[nH]1)C(C)C
InChI
InChI=1S/C42H50N8O6/c1-23(2)35(47-41(53)55-5)39(51)49-17-7-9-33(49)37-43-22-32(46-37)29-14-13-25-19-26(11-12-27(25)20-29)28-15-16-30-31(21-28)45-38(44-30)34-10-8-18-50(34)40(52)36(24(3)4)48-42(54)56-6/h11-16,19-24,33-36H,7-10,17-18H2,1-6H3,(H,43,46)(H,44,45)(H,47,53)(H,48,54)/t33-,34-,35-,36-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C42H50N8O6
Molecular Weight 762.91
AlogP 6.86
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 10.0
Polar Surface Area 174.64
Molecular species NEUTRAL
Aromatic Rings 5.0
Heavy Atoms 56.0

Pharmacology

Mechanism of Action Action Reference
Nonstructural protein 5A inhibitor INHIBITOR PubMed PubMed
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Hepatitis C virus (isolate Con1)
0.007 - - - -
Hepatitis C virus (isolate H77)
0.071 - - - -

Related Entries

Cross References

Resources Reference
ChEMBL CHEMBL3121849
DrugBank DB15652
FDA SRS AL3G001BI8
PubChem 52918888
SureChEMBL SCHEMBL7603463
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