None is not found in the database.

PIRACETAM


Synonyms	CL-871 Gabacet Myocalm NSC-758191 Nootrop Nootrop 1200 Nootrop 400 Nootrop 800 Nootropil Piracetam
Status
Molecule Category	Free-form
ATC	N06BX03
UNII	ZH516LNZ10
EPA CompTox	DTXSID5044491

Structure


InChI Key	GMZVRMREEHBGGF-UHFFFAOYSA-N
Smiles	NC(=O)CN1CCCC1=O
InChI	InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C6H10N2O2
Molecular Weight	142.16
AlogP	-0.91
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	2.0
Polar Surface Area	63.4
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	10.0

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Isomerase	-	-	-	-	29-129
Membrane receptor	-	-	-	-	29-129
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	88.77-103.12

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cricetulus griseus	-	-	-	-	88.77-103.12
Mus musculus	-	-	-	-	29-129

Cross References

Resources	Reference
ChEBI	32010
ChEMBL	CHEMBL36715
DrugBank	DB09210
DrugCentral	2197
FDA SRS	ZH516LNZ10
Guide to Pharmacology	4288
PDB	PZI
PubChem	4843
SureChEMBL	SCHEMBL20172
ZINC	ZINC000003812874

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025