Synonyms | |
Status | |
Molecule Category | Free-form |
UNII | MCN858TCP0 |
InChI Key | DMNOVGJWPASQDL-OAQYLSRUSA-N | |
---|---|---|
Smiles | ||
InChI |
|
Property Name | Value | |
---|---|---|
Molecular Formula | C22H30N2O2S | |
Molecular Weight | 386.56 | |
AlogP | 4.69 | |
Hydrogen Bond Acceptor | 5.0 | |
Hydrogen Bond Donor | 1.0 | |
Number of Rotational Bond | 7.0 | |
Polar Surface Area | 43.38 | |
Molecular species | BASE | |
Aromatic Rings | 2.0 | |
Heavy Atoms | 27.0 |
Mechanism of Action | Action | Reference | |
---|---|---|---|
Mu opioid receptor agonist | AGONIST | PubMed |
Protein: Mu opioid receptor Description: Mu-type opioid receptor Organism : Homo sapiens P35372 ENSG00000112038 |
||||
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | ||
---|---|---|---|---|---|---|---|
Ion channel
Voltage-gated ion channel
Potassium channels
Voltage-gated potassium channel
|
- | 6200 | - | - | - | ||
Ion channel
Voltage-gated ion channel
Voltage-gated calcium channel
|
- | 36000 | - | - | - | ||
Ion channel
Voltage-gated ion channel
Voltage-gated sodium channel
|
- | 4700-16500 | - | - | - | ||
Membrane receptor
Family A G protein-coupled receptor
Peptide receptor (family A GPCR)
Short peptide receptor (family A GPCR)
Opioid receptor
|
8-50 | - | - | 6 | - |
Resources | Reference | |
---|---|---|
ChEMBL | CHEMBL2443262 | |
DrugBank | DB14881 | |
FDA SRS | MCN858TCP0 | |
Guide to Pharmacology | 7334 | |
PubChem | 66553195 | |
SureChEMBL | SCHEMBL12542370 | |
ZINC | ZINC000096940334 |