NONIVAMIDE


Synonyms	AH-23491X FEMA NO. 2787 Hansaplast Hydroxymethoxybenzyl pelargonamide N-vanillylnonamide NSC-172795 Nonivamide Nonylic acid vanillyamide Pseudocapsaicin
Status
Molecule Category	Free-form
UNII	S846B891OR
EPA CompTox	DTXSID1034769


InChI Key	RGOVYLWUIBMPGK-UHFFFAOYSA-N
Smiles	CCCCCCCCC(=O)NCc1ccc(O)c(OC)c1
InChI	InChI=1S/C17H27NO3/c1-3-4-5-6-7-8-9-17(20)18-13-14-10-11-15(19)16(12-14)21-2/h10-12,19H,3-9,13H2,1-2H3,(H,18,20)

Property Name	Value
Molecular Formula	C17H27NO3
Molecular Weight	293.41
AlogP	3.77
Hydrogen Bond Acceptor	3.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	10.0
Polar Surface Area	58.56
Molecular species	NEUTRAL
Aromatic Rings	1.0
Heavy Atoms	21.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Ion channel Voltage-gated ion channel Transient receptor potential channel	223-550	-	-	-	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Cavia porcellus	400-400	-	-	-	-
Mus musculus	-	-	-	-	72.3
Rattus norvegicus	223-550	-	-	-	-

Header

Compound Name

Maximum Phase

Compound Structure

Smile

Inchi

InchiKey

Compound Properties

Molecular Formula

Molecular Weight

ALogP

PSA

Resources	Reference
ChEBI	46936
ChEMBL	CHEMBL75124
DrugBank	DB11324
FDA SRS	S846B891OR
Human Metabolome Database	HMDB0029846
PubChem	2998
SureChEMBL	SCHEMBL81939
ZINC	ZINC000001697652

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

NONIVAMIDE

Structure

Physicochemical Descriptors

Pharmacology

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