EcoDrugPlus


Synonyms	1263-W-94 1263W94 Maribavir
Status
Molecule Category	Free-form
ATC	J05AX10
UNII	PTB4X93HE1
EPA CompTox	DTXSID60170091

Synonyms

1263-W-94

1263W94

Maribavir

Status

Molecule Category

Free-form

ATC

J05AX10

UNII

PTB4X93HE1

EPA CompTox

DTXSID60170091


InChI Key	KJFBVJALEQWJBS-XUXIUFHCSA-N
Smiles	CC(C)Nc1nc2cc(Cl)c(Cl)cc2n1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O
InChI	InChI=1S/C15H19Cl2N3O4/c1-6(2)18-15-19-9-3-7(16)8(17)4-10(9)20(15)14-13(23)12(22)11(5-21)24-14/h3-4,6,11-14,21-23H,5H2,1-2H3,(H,18,19)/t11-,12-,13-,14-/m0/s1

InChI Key

KJFBVJALEQWJBS-XUXIUFHCSA-N

Smiles

CC(C)Nc1nc2cc(Cl)c(Cl)cc2n1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O

InChI

InChI=1S/C15H19Cl2N3O4/c1-6(2)18-15-19-9-3-7(16)8(17)4-10(9)20(15)14-13(23)12(22)11(5-21)24-14/h3-4,6,11-14,21-23H,5H2,1-2H3,(H,18,19)/t11-,12-,13-,14-/m0/s1

Property Name	Value
Molecular Formula	C15H19Cl2N3O4
Molecular Weight	376.24
AlogP	1.77
Hydrogen Bond Acceptor	7.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	4.0
Polar Surface Area	99.77
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	24.0

Property Name

Value

Molecular Formula

C15H19Cl2N3O4

Molecular Weight

376.24

AlogP

1.77

Hydrogen Bond Acceptor

7.0

Hydrogen Bond Donor

4.0

Number of Rotational Bond

4.0

Polar Surface Area

99.77

Molecular species

NEUTRAL

Aromatic Rings

2.0

Heavy Atoms

24.0

Mechanism of Action	Action	Reference
Phosphotransferase pUL97 inhibitor	INHIBITOR	PubMed PubMed PubMed PubMed

Mechanism of Action

Action

Reference

Phosphotransferase pUL97 inhibitor

INHIBITOR

PubMed PubMed PubMed PubMed

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Human herpesvirus 5	84-290	-	-	-	-

EC50(nM)

IC50(nM)

Kd(nM)

Ki(nM)

Inhibition(%)

Human herpesvirus 5

84-290

Resources	Reference
ChEMBL	CHEMBL515408
DrugBank	DB06234
FDA SRS	PTB4X93HE1
PubChem	471161
SureChEMBL	SCHEMBL791309
ZINC	ZINC000003824412

Resources

Reference

ChEMBL

DrugBank

FDA SRS

PubChem

SureChEMBL

ZINC

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

MARIBAVIR

Structure

Physicochemical Descriptors

Pharmacology

Cross References