EcoDrugPlus


Synonyms	Dilaudid Dilaudid-HP Dimorphone Hydromorphon Hydromorphone IDS-NH-004 Jurnista N02AA03 NSC-19046 Novolaudon Palladone
Status
Molecule Category	Free-form
ATC	N02AA03
UNII	Q812464R06
EPA CompTox	DTXSID8023133


InChI Key	WVLOADHCBXTIJK-YNHQPCIGSA-N
Smiles	CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@H]3[C@H]1C5
InChI	InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,16,19H,3,5-8H2,1H3/t10-,11+,16-,17-/m0/s1

Property Name	Value
Molecular Formula	C17H19NO3
Molecular Weight	285.34
AlogP	1.63
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	1.0
Polar Surface Area	49.77
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	21.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) Opioid receptor	2.6-11	-	-	0.28-38	-

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	2.6-11	-	-	0.28-38	-

Resources	Reference
ChEBI	5790
ChEMBL	CHEMBL398707
DrugBank	DB00327
DrugCentral	1393
FDA SRS	Q812464R06
Human Metabolome Database	HMDB0014472
Guide to Pharmacology	7082
KEGG	C07042
PharmGKB	PA449918
PubChem	5284570
SureChEMBL	SCHEMBL2255
ZINC	ZINC000000402954

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

This work is licensed under Creative Commons Attribution-ShareAlike 4.0 International License

Last update: Monday, 3 November 2025

HYDROMORPHONE

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