None is not found in the database.

GALANTAMINE


Synonyms	(-)-galantamine (-)-galanthamine Acumor xl Consion xl Elmino xl Galantamine Galanthamine Galsya xl Galzemic xl Gatalin xl Gazylan xl Lotprosin xl Luventa xl NSC-100058 Razadyne
Status
Molecule Category	Free-form
ATC	N06DA04
UNII	1T835Z585R
EPA CompTox	DTXSID2045606

Structure


InChI Key	ASUTZQLVASHGKV-JDFRZJQESA-N
Smiles	COc1ccc2c3c1O[C@H]1C[C@@H](O)C=C[C@@]31CCN(C)C2
InChI	InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C17H21NO3
Molecular Weight	287.36
AlogP	1.85
Hydrogen Bond Acceptor	4.0
Hydrogen Bond Donor	1.0
Number of Rotational Bond	1.0
Polar Surface Area	41.93
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	21.0

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Hydrolase	-	100-980	-	61.9-440	0.6-100

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Electrophorus electricus	-	250-665	-	428-440	0.6-100
Equus caballus	-	-	-	-	11.13-96.98
Homo sapiens	-	170-800	-	61.9-250	17.9-98.89
Mus musculus	-	-	-	-	91.94
Rattus norvegicus	-	920	-	-	-
Torpedo californica	-	360-652	-	-	-

Cross References

Resources	Reference
ChEBI	42944
ChEMBL	CHEMBL659
DrugBank	DB00674
DrugCentral	1272
FDA SRS	1T835Z585R
Human Metabolome Database	HMDB0014812
Guide to Pharmacology	6693
KEGG	C08526
PDB	GNT
PharmGKB	PA449726
PubChem	9651
SureChEMBL	SCHEMBL2577
ZINC	ZINC000000491073

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025