CYSTEAMINE

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Search structure


Synonyms	Cystagon Cysteamine L-1573 MEA Mercaptamine NSC-647528 Procysbi
Status
Molecule Category	Free-form
UNII	5UX2SD1KE2
EPA CompTox	DTXSID3022875

Structure


InChI Key	UFULAYFCSOUIOV-UHFFFAOYSA-N
Smiles	NCCS
InChI	InChI=1S/C2H7NS/c3-1-2-4/h4H,1-3H2

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C2H7NS
Molecular Weight	77.15
AlogP	-0.13
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	1.0
Polar Surface Area	26.02
Molecular species	BASE
Aromatic Rings	0.0
Heavy Atoms	4.0

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC22 family of organic cation and anion transporters	-	-	-	-	2.4

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	-	-	-	2.4
Rattus norvegicus	-	-	-	-	37

Cross References

Resources	Reference
ChEBI	17141
ChEMBL	CHEMBL602
DrugBank	DB00847
DrugCentral	768
FDA SRS	5UX2SD1KE2
Human Metabolome Database	HMDB0002991
Guide to Pharmacology	7440
KEGG	C01678
PDB	DHL
PharmGKB	PA449171
PubChem	6058
SureChEMBL	SCHEMBL16369
ZINC	ZINC000008034121

CONTENTS

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025