None is not found in the database.

CLIOQUINOL


Synonyms	4-stearylamino-phenyl-trimethylam. metilsulf. Clioquinol Domeform-hc Iodochlorhydroxyquin Iodochlorhydroxyquinolone NSC-3531 NSC-74938 Oralcer Quin-o-creme Vioform
Status
Molecule Category	Free-form
ATC	D08AH30 D09AA10 G01AC02 P01AA02 S02AA05
UNII	7BHQ856EJ5
EPA CompTox	DTXSID7022837


InChI Key	QCDFBFJGMNKBDO-UHFFFAOYSA-N
Smiles	Oc1c(I)cc(Cl)c2cccnc12
InChI	InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

Property Name	Value
Molecular Formula	C9H5ClINO
Molecular Weight	305.5
AlogP	3.2
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	1.0
Polar Surface Area	33.12
Molecular species	NEUTRAL
Aromatic Rings	2.0
Heavy Atoms	13.0

Mechanism of Action	Action	Reference
Copper chelating agent	CHELATING AGENT	PubMed PubMed

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Hydrolase	-	-	-	-	11.5
Membrane receptor	-	-	-	-	1.9-75
Unclassified protein	-	-	-	-	0-54.7

	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Homo sapiens	-	-	-	-	1.9-75
Mus musculus	-	-	-	-	0
Saccharomyces cerevisiae	-	-	-	-	0-54.7

Header

Compound Name

Maximum Phase

Compound Structure

Smile

Inchi

InchiKey

Compound Properties

Molecular Formula

Molecular Weight

ALogP

PSA

Resources	Reference
ChEBI	74460
ChEMBL	CHEMBL497
DrugBank	DB04815
DrugCentral	681
FDA SRS	7BHQ856EJ5
PDB	CQL
PubChem	2788
SureChEMBL	SCHEMBL3967
ZINC	ZINC000006409735

EcoDrug+ was developed under the PREMIER Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 875508. The JU receives support from the EU’s Horizon 2020 research and innovation programme and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The views reflect only the authors’ perspective and the JU is not responsible for any use that may be made of the information EcoDrug+ contains.

Elements of EcoDrug+ were developed under the Biocenter Finland Drug Discovery and Chemical Biology network. CSC-IT Center for Science Ltd is thanked for providing computational resources. Credit is given to Ensembl for collecting species images (provided under public domain licences such as Wikimedia and NHGRI).

Content of EcoDrug+ is provided without guarantee for correctness.

Cite Us:

Ashenafi Legehar, Siobhán Monaghan, Mael Briand, Akseli Niemelä, Leo Ghemtio, Ziaurrehman Tanoli, A Ross Brown, Charles R Tyler, Henri Xhaard, EcoDrug PLUS: an advanced database for drug target conservation analysis and environmental risk assessment, Nucleic Acids Research, 2025, gkaf1251 Read...

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Last update: Monday, 3 November 2025

CLIOQUINOL

Structure

Physicochemical Descriptors

Pharmacology

Related Entries

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