TESTOSTERONE

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Trade Names
Synonyms
Status
Molecule Category Free-form
ATC G03BA03
UNII 3XMK78S47O
EPA CompTox DTXSID8022371

Structure

InChI Key MUMGGOZAMZWBJJ-DYKIIFRCSA-N
Smiles C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O
InChI
InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H28O2
Molecular Weight 288.43
AlogP 3.88
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 1.0
Polar Surface Area 37.3
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 21.0

Pharmacology

Mechanism of Action Action Reference
Androgen Receptor agonist AGONIST Wikipedia FDA
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Cytochrome P450 Cytochrome P450 family 19 Cytochrome P450 family 19A Cytochrome P450 19A1
- - - 600 -
Enzyme Cytochrome P450 Cytochrome P450 family 3 Cytochrome P450 family 3A Cytochrome P450 3A4
- - - - 4.38-103
Enzyme Oxidoreductase
- - - - 7.5
Ion channel Voltage-gated ion channel Voltage-gated calcium channel
- 34-38.4 - - -
Ion channel Voltage-gated ion channel Voltage-gated sodium channel
- - - - 21.7
Secreted protein
- 14 0.631 190.55 -
Transcription factor Nuclear receptor Nuclear hormone receptor subfamily 3 Nuclear hormone receptor subfamily 3 group C Nuclear hormone receptor subfamily 3 group C member 4
1.1-3.162 2.7-30 - 1.4-29 0.1-100
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - -175.1-92.19
EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Cavia porcellus
- - - - 21.7
Cricetulus griseus
- - - - 79.99-92.19
Homo sapiens
1.1-3.162 2.7-38.4 0.631 600 -175.1-103
Mus musculus
1.995 - - - -
Rattus norvegicus
- 6.5 - 1.4-4.9 2

Target Conservation

Protein: Androgen Receptor
Description: Androgen receptor
Organism : Homo sapiens
P10275 ENSG00000169083

Related Entries

Environmental Exposure

Environmental Exposure Map
Countries
Malaysia
Vietnam

Cross References

Resources Reference
ChEBI 17347
ChEMBL CHEMBL386630
DrugBank DB00624
DrugCentral 2607
FDA SRS 3XMK78S47O
Guide to Pharmacology 2858
KEGG C00535
PDB TES
PharmGKB PA451627
PubChem 6013
SureChEMBL SCHEMBL8452
ZINC ZINC000118912393
CONTENTS