| Trade Names | |
| Synonyms | |
| Status | |
| Molecule Category | Mixture |
| ATC | J05AH03 |
| UNII | QW7Y7ZR15U |
| EPA CompTox | DTXSID60146317 |
Structure
| InChI Key | XRQDFNLINLXZLB-CKIKVBCHSA-N |
|---|---|
| Smiles | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C15H34N4O7 |
| Molecular Weight | 382.46 |
| AlogP | -0.14 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 6.0 |
| Number of Rotational Bond | 7.0 |
| Polar Surface Area | 148.53 |
| Molecular species | ZWITTERION |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 23.0 |
Pharmacology
| Mechanism of Action | Action | Reference |
|---|---|---|
| Neuraminidase inhibitor | INHIBITOR | FDA |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Hydrolase
|
- | 0.07-451 | - | 0.83 | - | |
|
Enzyme
|
- | 0.07-451 | - | 0.83 | - |
Influenza A virus
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Influenza A virus (A/Brevig Mission/1/1918(H1N1))
).png)
Influenza A virus (A/Brisbane/10/2007(H3N2))
).png)
Influenza A virus (A/Brisbane/59/2007(H1N1))
).png)
Influenza A virus (A/Chicken/Laos/Xaythiani 26/2006(H5N1))
).png)
Influenza A virus (A/New Caledonia/20/1999(H1N1))
).png)
Influenza A virus (A/Shanghai/01/2014(H7N9))
).png)
Influenza A virus (A/Texas/12/2007(H3N2))
).png)
Influenza A virus (A/Vietnam/1194/2004(H5N1))
).png)
Influenza A virus (A/WSN/1933(H1N1))
).png)
Influenza A virus (A/Washington/01/2007(H3N2))
).png)
Influenza A virus (A/environment/Viet Nam/1203/2004(H5N1))
Influenza B virus
.png)
Influenza B virus (B/Perth/211/2001)
unidentified adenovirus
unidentified influenza virus
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3989402 |
| FDA SRS | QW7Y7ZR15U |
| PubChem | 11954371 |
| ChEBI | 85202 |
| ChEMBL | CHEMBL139367 |
| DrugBank | DB06614 |
| DrugCentral | 4823 |
| FDA SRS | IDL9Q29886 |
| PDB | BCZ |
| PubChem | 11954371 |
| SureChEMBL | SCHEMBL744373 |
| ZINC | ZINC000003981610 |
CONTENTS
